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Search of human proteins with 40788011
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40788011 claudin 8 [Homo sapiens]
(225 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40788011 claudin 8 [Homo sapiens] 456 e-129
gi|6912316 claudin 17 [Homo sapiens] 271 3e-73
gi|4502875 claudin 3 [Homo sapiens] 206 2e-53
gi|11141861 claudin 9 [Homo sapiens] 201 3e-52
gi|153792768 claudin 6 [Homo sapiens] 197 8e-51
gi|4502877 claudin 4 [Homo sapiens] 193 9e-50
gi|195947374 claudin 5 [Homo sapiens] 186 2e-47
gi|195947372 claudin 5 [Homo sapiens] 186 2e-47
gi|153792186 claudin 7 [Homo sapiens] 184 7e-47
gi|10863887 claudin 1 [Homo sapiens] 171 4e-43
gi|225703142 claudin 14 [Homo sapiens] 162 2e-40
gi|21536294 claudin 14 [Homo sapiens] 162 2e-40
gi|225703138 claudin 14 [Homo sapiens] 162 2e-40
gi|6912314 claudin 14 [Homo sapiens] 162 2e-40
gi|225703140 claudin 14 [Homo sapiens] 162 2e-40
gi|183979973 claudin 19 isoform a [Homo sapiens] 161 5e-40
gi|183979975 claudin 19 isoform b [Homo sapiens] 161 5e-40
gi|9966781 claudin 2 [Homo sapiens] 146 2e-35
gi|5921465 claudin 10 isoform b [Homo sapiens] 133 1e-31
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 126 1e-29
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 126 1e-29
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 126 2e-29
gi|33598916 claudin 10 isoform a [Homo sapiens] 126 2e-29
gi|7656981 claudin 15 [Homo sapiens] 125 2e-29
gi|47716519 claudin 20 [Homo sapiens] 123 1e-28
gi|162417973 claudin 22 [Homo sapiens] 120 1e-27
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 114 9e-26
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 113 1e-25
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 113 1e-25
gi|157820127 claudin-like [Homo sapiens] 100 8e-22
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 456 bits (1172), Expect = e-129
Identities = 225/225 (100%), Positives = 225/225 (100%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI
Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL
Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
Query: 181 LFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV 225
LFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV
Sbjct: 181 LFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV 225
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 271 bits (693), Expect = 3e-73
Identities = 124/214 (57%), Positives = 159/214 (74%), Gaps = 4/214 (1%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA + L+IAGL LG +GMVGT+A T++PQWRVSAF+ +NI+VFE WEGLWMNC+RQA +
Sbjct: 1 MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
R+QCK Y SLLAL P L+ AR LMC A +S +A ++ I GMK +CTG NE+ KA++L
Sbjct: 61 RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLG 120
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
T+G++FI+TG+ VLIPVSW AN IIRDFYN +++ QKRELG AL+LGW +A VL +GG
Sbjct: 121 TSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGG 180
Query: 181 LFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKK 214
L C CCN K YRY +P +R HT K+
Sbjct: 181 LLCGFCCCNRKKQGYRYPVPGYRVP----HTDKR 210
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 206 bits (523), Expect = 2e-53
Identities = 104/223 (46%), Positives = 140/223 (62%), Gaps = 10/223 (4%)
Query: 6 LEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCK 65
LEI G L +G +GT+ +P WRVSAFI +NI+ +N WEGLWMNCV Q+ +MQCK
Sbjct: 5 LEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCK 64
Query: 66 IYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGII 125
+YDSLLAL DLQAAR L+ A +++ ++A++G +CT C D + KA I + AG++
Sbjct: 65 VYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQD-DTAKAKITIVAGVL 123
Query: 126 FIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGALFCCV 185
F++ ++ L+PVSW AN IIRDFYN +V AQKRE+G LY+GW A + ++GGAL CC
Sbjct: 124 FLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCCS 183
Query: 186 FCCNEK---SSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV 225
EK ++ YS P S TG Y R YV
Sbjct: 184 CPPREKKYTATKVVYSAPRSTGPGASLGTG------YDRKDYV 220
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 201 bits (512), Expect = 3e-52
Identities = 104/207 (50%), Positives = 139/207 (67%), Gaps = 9/207 (4%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA+ LE+ G+ L +G +GT+ +P W+V+AFI N+IVV + WEGLWM+CV Q+
Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
+MQCK+YDSLLAL DLQAAR L A +++ L ++AI G +CT C D E KA I+L
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVED-EGAKARIVL 119
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
TAG+I ++ G++VLIPV W A+AII+DFYN +V A KRELG +LYLGW A +L++GG
Sbjct: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG 179
Query: 181 LFCCVFCC------NEKSSSYRYSIPS 201
L CC C + YSIPS
Sbjct: 180 LLCCT--CPPPQVERPRGPRLGYSIPS 204
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 197 bits (500), Expect = 8e-51
Identities = 101/225 (44%), Positives = 145/225 (64%), Gaps = 5/225 (2%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA+ ++I G+ L +G V + +P W+V+AFI N+IVV + WEGLWM+CV Q+
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
+MQCK+YDSLLAL DLQAAR L A +++ ++ + G KCT C + + KA ++L
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDS-KARLVL 119
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
T+GI+F+I+G++ LIPV W A+AIIRDFYN +V AQKRELG +LYLGW + +L++GG
Sbjct: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG 179
Query: 181 LFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV 225
L CC C + S + + + T+ + G PS Y YV
Sbjct: 180 LLCCT-CPSGGSQGPSHYMARYSTSAPAISRG---PSEYPTKNYV 220
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 193 bits (491), Expect = 9e-50
Identities = 86/184 (46%), Positives = 130/184 (70%), Gaps = 1/184 (0%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA+ L++ G+ L +G + + +P WRV+AFI +NIV + WEGLWMNCV Q+
Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
+MQCK+YDSLLAL DLQAAR L+ + +++ L +++++G KCT C D E KA ++
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLED-ESAKAKTMI 119
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
AG++F++ G++V++PVSW A+ II+DFYN +V QKRE+G +LY+GW + +L++GG
Sbjct: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG 179
Query: 181 LFCC 184
L CC
Sbjct: 180 LLCC 183
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 186 bits (471), Expect = 2e-47
Identities = 90/213 (42%), Positives = 134/213 (62%), Gaps = 5/213 (2%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
M + ALEI GL L VG G + +P W+V+AF+++NIV + W+GLWM+CV Q+
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
MQCK+YDS+LALS ++QAAR L +A +++F+A + + G +CT C KA + L
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPG-PAKARVAL 204
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
T G++++ G++ L+P+ W AN ++R+FY+ V V+QK ELG ALY+GW +L+VGG
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
Query: 181 LFCC-VFCCN---EKSSSYRYSIPSHRTTQKSY 209
L CC + C + S +YS P T Y
Sbjct: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDY 297
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 186 bits (471), Expect = 2e-47
Identities = 90/213 (42%), Positives = 134/213 (62%), Gaps = 5/213 (2%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
M + ALEI GL L VG G + +P W+V+AF+++NIV + W+GLWM+CV Q+
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
MQCK+YDS+LALS ++QAAR L +A +++F+A + + G +CT C KA + L
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPG-PAKARVAL 204
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
T G++++ G++ L+P+ W AN ++R+FY+ V V+QK ELG ALY+GW +L+VGG
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
Query: 181 LFCC-VFCCN---EKSSSYRYSIPSHRTTQKSY 209
L CC + C + S +YS P T Y
Sbjct: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDY 297
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 184 bits (466), Expect = 7e-47
Identities = 86/196 (43%), Positives = 126/196 (64%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA L++ G + +G VG VA T +PQW++S++ +NI+ + ++GLWM+CV Q+
Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
M CK+YDS+LALS LQA R LM + V+ FLA +A +GMKCTRC GD++ KA I +
Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
GIIFI+ G+ L+ SW + I+ DFYN ++ K E G A+++GW + ++I+GGA
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
Query: 181 LFCCVFCCNEKSSSYR 196
L C NE + YR
Sbjct: 181 LLSCSCPGNESKAGYR 196
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 171 bits (434), Expect = 4e-43
Identities = 76/195 (38%), Positives = 122/195 (62%), Gaps = 2/195 (1%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA L++ G L +G +G + T +PQWR+ ++ +NIV + +EGLWM+CV Q+
Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
++QCK++DSLL LS LQA R LM ++ +A +A +GMKC +C D+E K + +
Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
G IF++ G+ +L+ +W N I+++FY+ + V + E G+AL+ GW A + ++GGA
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
Query: 181 LFCCVFCCNEKSSSY 195
L CC C K++SY
Sbjct: 181 LLCC--SCPRKTTSY 193
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 162 bits (411), Expect = 2e-40
Identities = 79/205 (38%), Positives = 125/205 (60%), Gaps = 3/205 (1%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA+ A+++ G L +GMVGT+ T++P WR +A + NI+ ++ +GLWM CV +
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
QC+IY SLLAL DLQAAR LM + ++S +A A++GMKCTRC K +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
G +FI+ G++ ++ VSW N ++++FYN ++ K E+G+ALYLG+ ++ + ++GG
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 LFCCVFCCNEKSSSYRYSIPSHRTT 205
L C C +++ Y P TT
Sbjct: 180 LLC--LSCQDEAPYRPYQAPPRATT 202
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 162 bits (411), Expect = 2e-40
Identities = 79/205 (38%), Positives = 125/205 (60%), Gaps = 3/205 (1%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA+ A+++ G L +GMVGT+ T++P WR +A + NI+ ++ +GLWM CV +
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
QC+IY SLLAL DLQAAR LM + ++S +A A++GMKCTRC K +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
G +FI+ G++ ++ VSW N ++++FYN ++ K E+G+ALYLG+ ++ + ++GG
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 LFCCVFCCNEKSSSYRYSIPSHRTT 205
L C C +++ Y P TT
Sbjct: 180 LLC--LSCQDEAPYRPYQAPPRATT 202
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 162 bits (411), Expect = 2e-40
Identities = 79/205 (38%), Positives = 125/205 (60%), Gaps = 3/205 (1%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA+ A+++ G L +GMVGT+ T++P WR +A + NI+ ++ +GLWM CV +
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
QC+IY SLLAL DLQAAR LM + ++S +A A++GMKCTRC K +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
G +FI+ G++ ++ VSW N ++++FYN ++ K E+G+ALYLG+ ++ + ++GG
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 LFCCVFCCNEKSSSYRYSIPSHRTT 205
L C C +++ Y P TT
Sbjct: 180 LLC--LSCQDEAPYRPYQAPPRATT 202
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 162 bits (411), Expect = 2e-40
Identities = 79/205 (38%), Positives = 125/205 (60%), Gaps = 3/205 (1%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA+ A+++ G L +GMVGT+ T++P WR +A + NI+ ++ +GLWM CV +
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
QC+IY SLLAL DLQAAR LM + ++S +A A++GMKCTRC K +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
G +FI+ G++ ++ VSW N ++++FYN ++ K E+G+ALYLG+ ++ + ++GG
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 LFCCVFCCNEKSSSYRYSIPSHRTT 205
L C C +++ Y P TT
Sbjct: 180 LLC--LSCQDEAPYRPYQAPPRATT 202
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 162 bits (411), Expect = 2e-40
Identities = 79/205 (38%), Positives = 125/205 (60%), Gaps = 3/205 (1%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA+ A+++ G L +GMVGT+ T++P WR +A + NI+ ++ +GLWM CV +
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
QC+IY SLLAL DLQAAR LM + ++S +A A++GMKCTRC K +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
G +FI+ G++ ++ VSW N ++++FYN ++ K E+G+ALYLG+ ++ + ++GG
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 LFCCVFCCNEKSSSYRYSIPSHRTT 205
L C C +++ Y P TT
Sbjct: 180 LLC--LSCQDEAPYRPYQAPPRATT 202
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 161 bits (407), Expect = 5e-40
Identities = 72/184 (39%), Positives = 114/184 (61%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA L++ G FL G VG +A T +PQW+ S++ + I+ +EGLWM+C Q+
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
++QCK+YDSLLAL +Q+AR LM A ++ F+A +++++GMKCTR N K + +
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
G +FI+ G+ L VSW A + ++F+N V + E G AL++GW +A + ++GG+
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 181 LFCC 184
CC
Sbjct: 181 FLCC 184
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 161 bits (407), Expect = 5e-40
Identities = 72/184 (39%), Positives = 114/184 (61%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA L++ G FL G VG +A T +PQW+ S++ + I+ +EGLWM+C Q+
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
++QCK+YDSLLAL +Q+AR LM A ++ F+A +++++GMKCTR N K + +
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
G +FI+ G+ L VSW A + ++F+N V + E G AL++GW +A + ++GG+
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 181 LFCC 184
CC
Sbjct: 181 FLCC 184
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 146 bits (368), Expect = 2e-35
Identities = 70/197 (35%), Positives = 122/197 (61%), Gaps = 3/197 (1%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA+ L++ G LG +G++GT+ ++P W+ S+++ +IV F +GLWM C +
Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
QC IY +LL L D+QAA+ +M +S +S LA +++++GM+CT ++ + K + +
Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQES-RAKDRVAV 119
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
G+ FI+ G++ IPV+W + I+RDFY+ +V + K E+GEALYLG ++L ++ G
Sbjct: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGI 179
Query: 181 LFCCVFCCNEKSSSYRY 197
+ C F C+ + + Y
Sbjct: 180 ILC--FSCSSQRNRSNY 194
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 133 bits (335), Expect = 1e-31
Identities = 78/225 (34%), Positives = 118/225 (52%), Gaps = 4/225 (1%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA+ A EI + G V + W+VS I+ ++ +W LW CV +
Sbjct: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVST-IDGTVITTATYWANLWKACVTDSTG 59
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
CK + S+LAL +QA RGLM AA + F + A+ GMKCT+ G ++K KA I
Sbjct: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTK-VGGSDKAKAKIAC 118
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
AGI+FI++G+ + S AN I +F++ + V QK ELG AL++GW A + I+GG
Sbjct: 119 LAGIVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGV 177
Query: 181 LFCCVFCCNEKSSSYRYS-IPSHRTTQKSYHTGKKSPSVYSRSQY 224
+FC N K+ Y Y+ S +++ YH G+ + Q+
Sbjct: 178 IFCFSISDNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQF 222
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 126 bits (317), Expect = 1e-29
Identities = 69/216 (31%), Positives = 115/216 (53%), Gaps = 5/216 (2%)
Query: 5 ALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQC 64
A++ GL L +G + ++ T +P W+ N + EN+ GLW CV Q + MQC
Sbjct: 8 AMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEM---ENWTMGLWQTCVIQEEVGMQC 64
Query: 65 KIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGI 124
K +DS LAL +L+ +R LM ++ + FL +++ G+ C R +K +L+ GI
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 125 IFIITGMVVLIPVSWVANAIIRDFYN-SIVNVAQKRELGEALYLGWTTALVLIVGGALFC 183
+ +G+ L+PVSWVA+ +++F++ ++ + + E GEAL+LGW L L++GG L
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184
Query: 184 CVFCCNEKSSSYRYSIPSHRTTQKSY-HTGKKSPSV 218
C C + + + + TQ Y G P V
Sbjct: 185 CAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV 220
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 126 bits (317), Expect = 1e-29
Identities = 69/216 (31%), Positives = 115/216 (53%), Gaps = 5/216 (2%)
Query: 5 ALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQC 64
A++ GL L +G + ++ T +P W+ N + EN+ GLW CV Q + MQC
Sbjct: 8 AMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEM---ENWTMGLWQTCVIQEEVGMQC 64
Query: 65 KIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGI 124
K +DS LAL +L+ +R LM ++ + FL +++ G+ C R +K +L+ GI
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 125 IFIITGMVVLIPVSWVANAIIRDFYN-SIVNVAQKRELGEALYLGWTTALVLIVGGALFC 183
+ +G+ L+PVSWVA+ +++F++ ++ + + E GEAL+LGW L L++GG L
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184
Query: 184 CVFCCNEKSSSYRYSIPSHRTTQKSY-HTGKKSPSV 218
C C + + + + TQ Y G P V
Sbjct: 185 CAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV 220
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 126 bits (316), Expect = 2e-29
Identities = 69/216 (31%), Positives = 115/216 (53%), Gaps = 5/216 (2%)
Query: 5 ALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQC 64
A++ GL L +G + ++ T +P W+ N + EN+ GLW CV Q + MQC
Sbjct: 8 AMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEM---ENWTMGLWQTCVIQEEVGMQC 64
Query: 65 KIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGI 124
K +DS LAL +L+ +R LM ++ + FL +++ G+ C R +K +L+ GI
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 125 IFIITGMVVLIPVSWVANAIIRDFYN-SIVNVAQKRELGEALYLGWTTALVLIVGGALFC 183
+ +G+ L+PVSWVA+ +++F++ ++ + + E GEAL+LGW L L++GG L
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184
Query: 184 CVFCCNEKSSSYRYSIPSHRTTQKSY-HTGKKSPSV 218
C C + + + + TQ Y G P V
Sbjct: 185 CAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV 220
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 126 bits (316), Expect = 2e-29
Identities = 73/214 (34%), Positives = 118/214 (55%), Gaps = 5/214 (2%)
Query: 13 LGGVGMVGT-VAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCKIYDSLL 71
+ GVG G VA T +W+V+ ++++ ++GLWMNC A C+ + ++
Sbjct: 10 VSGVGGFGALVAATTSNEWKVTTRA-SSVITATWVYQGLWMNCAGNALGSFHCRPHFTIF 68
Query: 72 ALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGIIFIITGM 131
++ +QA RGLM AA + F + A+ GMKCT+ G ++K KA I AGI+FI++G+
Sbjct: 69 KVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTK-VGGSDKAKAKIACLAGIVFILSGL 127
Query: 132 VVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGALFCCVFCCNEK 191
+ S AN I +F++ + V QK ELG AL++GW A + I+GG +FC N K
Sbjct: 128 CSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNK 186
Query: 192 SSSYRYS-IPSHRTTQKSYHTGKKSPSVYSRSQY 224
+ Y Y+ S +++ YH G+ + Q+
Sbjct: 187 TPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQF 220
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 125 bits (315), Expect = 2e-29
Identities = 76/227 (33%), Positives = 111/227 (48%), Gaps = 8/227 (3%)
Query: 5 ALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQC 64
A+E G F+ VG++ WRVS + N++ +E LW +C + C
Sbjct: 4 AVETFGFFMATVGLLMLGVTLPNSYWRVST-VHGNVITTNTIFENLWFSCATDSLGVYNC 62
Query: 65 KIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGI 124
+ S+LALS +QA R LM A ++ FL ++ I G++CT G KA + TAG
Sbjct: 63 WEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGA 122
Query: 125 IFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGALFCC 184
+ I+ G+ ++ +SW A I RDF++ + K ELG ALYLGW+ +L+ I+GG C
Sbjct: 123 LHILAGICGMVAISWYAFNITRDFFDPLY-PGTKYELGPALYLGWSASLISILGGLCLCS 181
Query: 185 VFCCNE-----KSSSYRYSIP-SHRTTQKSYHTGKKSPSVYSRSQYV 225
CC S+ Y P S S G S Y R+ YV
Sbjct: 182 ACCCGSDEDPAASARRPYQAPVSVMPVATSDQEGDSSFGKYGRNAYV 228
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 123 bits (308), Expect = 1e-28
Identities = 71/225 (31%), Positives = 116/225 (51%), Gaps = 6/225 (2%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA+ L++ L G+ G + T++P W+V+ +++NI+ GLWM+C +
Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
C + S+L+L +QAAR M A V+S L + +GMKCTR GD E K+H
Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRE-TKSHASF 119
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
G+ F+ G+ LI W II +F + V + K E G A+Y+G+ +A++L + G
Sbjct: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179
Query: 181 LFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV 225
+FC C +++ R P T Q +T ++ S ++ YV
Sbjct: 180 IFCT--SCIKRNPEARLDPP---TQQPISNTQLENNSTHNLKDYV 219
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 120 bits (300), Expect = 1e-27
Identities = 62/182 (34%), Positives = 103/182 (56%), Gaps = 4/182 (2%)
Query: 7 EIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCKI 66
++AG+ L +G V + +P W+ N + EN+ GLW CV Q + MQCK
Sbjct: 10 QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEM---ENWTMGLWQTCVIQEEVGMQCKD 66
Query: 67 YDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGIIF 126
+DS LAL +L+ +R LM ++ + FL +++ G+ C R +K +L+ GI+
Sbjct: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
Query: 127 IITGMVVLIPVSWVANAIIRDFYN-SIVNVAQKRELGEALYLGWTTALVLIVGGALFCCV 185
+G+ L+PVSWVA+ +++F++ ++ + + E GEAL+LGW L L++GG L C
Sbjct: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
Query: 186 FC 187
C
Sbjct: 187 AC 188
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 114 bits (284), Expect = 9e-26
Identities = 60/194 (30%), Positives = 101/194 (52%), Gaps = 12/194 (6%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
MA A + G + +G+ G +A T M QW N + N+ +GLW +CVR+++
Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNY-QGLWRSCVRESSG 59
Query: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
+C+ Y +LL L LQA R LM V+ + +++I +KC R + KA++ L
Sbjct: 60 FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVN-----------VAQKRELGEALYLGW 169
T+GI+FI++G+ + VS AN ++ +F+ S N V + G AL++GW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 170 TTALVLIVGGALFC 183
+ ++GG + C
Sbjct: 180 VAGGLTLIGGVMMC 193
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 113 bits (283), Expect = 1e-25
Identities = 71/214 (33%), Positives = 110/214 (51%), Gaps = 24/214 (11%)
Query: 13 LGGVGMVGT-VAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCKIYDSLL 71
+ GVG G VA T +W+V+ ++++ ++GLWMNC
Sbjct: 10 VSGVGGFGALVAATTSNEWKVTTRA-SSVITATWVYQGLWMNCAGY-------------- 54
Query: 72 ALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGIIFIITGM 131
+QA RGLM AA + F + A+ GMKCT+ G ++K KA I AGI+FI++G+
Sbjct: 55 -----IQACRGLMIAAVSLGFFGSIFALFGMKCTK-VGGSDKAKAKIACLAGIVFILSGL 108
Query: 132 VVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGALFCCVFCCNEK 191
+ S AN I +F++ + V QK ELG AL++GW A + I+GG +FC N K
Sbjct: 109 CSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNK 167
Query: 192 SSSYRYS-IPSHRTTQKSYHTGKKSPSVYSRSQY 224
+ Y Y+ S +++ YH G+ + Q+
Sbjct: 168 TPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQF 201
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 113 bits (283), Expect = 1e-25
Identities = 60/195 (30%), Positives = 103/195 (52%), Gaps = 14/195 (7%)
Query: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIV-VFENFWEGLWMNCVRQAN 59
M+T ++ L +G+ G +A T M W +N + VF+ +EGLW +CVRQ++
Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQ--YEGLWRSCVRQSS 58
Query: 60 IRMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHIL 119
+C+ Y ++L L LQA R LM V+ + +++I +KC R + KA++
Sbjct: 59 GFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMT 118
Query: 120 LTAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVN-----------VAQKRELGEALYLG 168
LT+GI+FI++G+ + VS AN ++ +F+ S N V + G AL++G
Sbjct: 119 LTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVG 178
Query: 169 WTTALVLIVGGALFC 183
W + ++GG + C
Sbjct: 179 WVAGGLTLIGGVMMC 193
>gi|157820127 claudin-like [Homo sapiens]
Length = 229
Score = 100 bits (250), Expect = 8e-22
Identities = 58/187 (31%), Positives = 95/187 (50%), Gaps = 4/187 (2%)
Query: 6 LEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCK 65
+++ GL L +G V + T++PQW+ N + E + G+W CV + + CK
Sbjct: 9 VQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEM---ETWIMGIWEVCVDREEVATVCK 65
Query: 66 IYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGII 125
++S L+L +LQ AR LM A+ + L ++ G +C + K + L +
Sbjct: 66 AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
Query: 126 FIITGMVVLIPVSWVANAIIRDFY-NSIVNVAQKRELGEALYLGWTTALVLIVGGALFCC 184
L+PVSWVA+A I+DF+ +SI ++ + E G ALYLGW + L +GG L
Sbjct: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
Query: 185 VFCCNEK 191
C ++
Sbjct: 186 SACLGKE 192
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.136 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,453,382
Number of Sequences: 37866
Number of extensions: 276081
Number of successful extensions: 1182
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1113
Number of HSP's gapped (non-prelim): 56
length of query: 225
length of database: 18,247,518
effective HSP length: 99
effective length of query: 126
effective length of database: 14,498,784
effective search space: 1826846784
effective search space used: 1826846784
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.