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Search of human proteins with 40538728
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40538728 pleckstrin homology domain containing, family M
(with RUN domain) member 1 [Homo sapiens]
(1056 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40538728 pleckstrin homology domain containing, family M (wit... 2135 0.0
gi|239756837 PREDICTED: similar to pleckstrin homology domain co... 1094 0.0
gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo ... 1033 0.0
gi|122937347 pleckstrin homology domain containing, family M, me... 264 4e-70
gi|46447820 differentially expressed in FDCP 8 isoform 1 [Homo s... 161 3e-39
gi|156151402 hypothetical protein LOC80183 [Homo sapiens] 155 2e-37
gi|224548938 hypothetical protein LOC9711 isoform 1 [Homo sapiens] 129 1e-29
gi|150456467 hypothetical protein LOC9711 isoform 2 [Homo sapiens] 129 1e-29
gi|116292170 RUN domain containing 2A [Homo sapiens] 94 5e-19
gi|221139728 pleckstrin homology domain containing, family M (wi... 69 2e-11
gi|7662352 RUN and FYVE domain containing 3 isoform 2 [Homo sapi... 58 4e-08
gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo sap... 58 4e-08
gi|195220720 RUN and FYVE domain containing 3 isoform 3 [Homo sa... 58 4e-08
gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] 56 2e-07
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 55 5e-07
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 55 5e-07
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 55 5e-07
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 50 1e-05
gi|44889475 RAB6 interacting protein 1 [Homo sapiens] 47 1e-04
gi|197304746 RUN domain containing 3B isoform c [Homo sapiens] 43 0.002
gi|19923090 RUN domain containing 3B isoform a [Homo sapiens] 42 0.002
gi|197304744 RUN domain containing 3B isoform b [Homo sapiens] 42 0.004
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 40 0.015
gi|55741677 SET domain containing 1A [Homo sapiens] 39 0.020
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 39 0.020
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 39 0.026
gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 38 0.044
gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 38 0.044
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 38 0.044
gi|17149830 G protein-coupled receptor kinase interacting ArfGAP... 38 0.044
>gi|40538728 pleckstrin homology domain containing, family M (with RUN
domain) member 1 [Homo sapiens]
Length = 1056
Score = 2135 bits (5532), Expect = 0.0
Identities = 1056/1056 (100%), Positives = 1056/1056 (100%)
Query: 1 MLSVVENGLDPQAAIPVIKKKLVGSVKALQKQYVSLDTVVTSEDGDANTMCSALEAVFIH 60
MLSVVENGLDPQAAIPVIKKKLVGSVKALQKQYVSLDTVVTSEDGDANTMCSALEAVFIH
Sbjct: 1 MLSVVENGLDPQAAIPVIKKKLVGSVKALQKQYVSLDTVVTSEDGDANTMCSALEAVFIH 60
Query: 61 GLHAKHIRAEAGGKRKKSAHQKPLPQPVFWPLLKAVTHKHIISELEHLTFVNTDVGRCRA 120
GLHAKHIRAEAGGKRKKSAHQKPLPQPVFWPLLKAVTHKHIISELEHLTFVNTDVGRCRA
Sbjct: 61 GLHAKHIRAEAGGKRKKSAHQKPLPQPVFWPLLKAVTHKHIISELEHLTFVNTDVGRCRA 120
Query: 121 WLRLALNDGLMECYLKLLLQEQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSY 180
WLRLALNDGLMECYLKLLLQEQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSY
Sbjct: 121 WLRLALNDGLMECYLKLLLQEQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSY 180
Query: 181 KSAILNEWTLTPLALSGLCPLSELDPLSTSGAELQRKESLDSISHSSGSEDIEVHHSGHK 240
KSAILNEWTLTPLALSGLCPLSELDPLSTSGAELQRKESLDSISHSSGSEDIEVHHSGHK
Sbjct: 181 KSAILNEWTLTPLALSGLCPLSELDPLSTSGAELQRKESLDSISHSSGSEDIEVHHSGHK 240
Query: 241 IRRNQKLTASSLSLDTASSSQLSCSLNSDSCLLQENGSKSPDHCEEPMSCDSDLGTANAE 300
IRRNQKLTASSLSLDTASSSQLSCSLNSDSCLLQENGSKSPDHCEEPMSCDSDLGTANAE
Sbjct: 241 IRRNQKLTASSLSLDTASSSQLSCSLNSDSCLLQENGSKSPDHCEEPMSCDSDLGTANAE 300
Query: 301 DSDRSLQEVLLEFSKAQVNSVPTNGLSQETEIPTPQASLSLHGLNTSTYLHCEAPAEPLP 360
DSDRSLQEVLLEFSKAQVNSVPTNGLSQETEIPTPQASLSLHGLNTSTYLHCEAPAEPLP
Sbjct: 301 DSDRSLQEVLLEFSKAQVNSVPTNGLSQETEIPTPQASLSLHGLNTSTYLHCEAPAEPLP 360
Query: 361 AQAASGTQDGVHVQEPRPQAPSPLDLQQPVESTSGQQPSSTVSETAREVGQGNGLQKAQA 420
AQAASGTQDGVHVQEPRPQAPSPLDLQQPVESTSGQQPSSTVSETAREVGQGNGLQKAQA
Sbjct: 361 AQAASGTQDGVHVQEPRPQAPSPLDLQQPVESTSGQQPSSTVSETAREVGQGNGLQKAQA 420
Query: 421 HDGAGLKLVVSSPTSPKNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRH 480
HDGAGLKLVVSSPTSPKNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRH
Sbjct: 421 HDGAGLKLVVSSPTSPKNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRH 480
Query: 481 FSQEPRKNCSLGALDQACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGT 540
FSQEPRKNCSLGALDQACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGT
Sbjct: 481 FSQEPRKNCSLGALDQACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGT 540
Query: 541 VERRGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSG 600
VERRGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSG
Sbjct: 541 VERRGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSG 600
Query: 601 KKLALRASSQDEAEDWLDRVREALQKVRPQQEDEWVNVQYPDQPEEPPEAPQGCLSPSDL 660
KKLALRASSQDEAEDWLDRVREALQKVRPQQEDEWVNVQYPDQPEEPPEAPQGCLSPSDL
Sbjct: 601 KKLALRASSQDEAEDWLDRVREALQKVRPQQEDEWVNVQYPDQPEEPPEAPQGCLSPSDL 660
Query: 661 LSEPAALQGTQFDWSSAQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEK 720
LSEPAALQGTQFDWSSAQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEK
Sbjct: 661 LSEPAALQGTQFDWSSAQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEK 720
Query: 721 MLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYL 780
MLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYL
Sbjct: 721 MLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYL 780
Query: 781 ETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGF 840
ETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGF
Sbjct: 781 ETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGF 840
Query: 841 SFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLIN 900
SFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLIN
Sbjct: 841 SFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLIN 900
Query: 901 LQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKRLNHRNYLLESPHRF 960
LQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKRLNHRNYLLESPHRF
Sbjct: 901 LQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKRLNHRNYLLESPHRF 960
Query: 961 SVADLQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICQHHDIIFPFEFDTTVR 1020
SVADLQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICQHHDIIFPFEFDTTVR
Sbjct: 961 SVADLQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICQHHDIIFPFEFDTTVR 1020
Query: 1021 CAECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA 1056
CAECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA
Sbjct: 1021 CAECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA 1056
>gi|239756837 PREDICTED: similar to pleckstrin homology domain
containing, family M (with RUN domain) member 1, partial
[Homo sapiens]
Length = 623
Score = 1094 bits (2829), Expect = 0.0
Identities = 557/635 (87%), Positives = 566/635 (89%), Gaps = 29/635 (4%)
Query: 437 KNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRHFSQEPRKNCSLGALDQ 496
KNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRHFSQEPRKNCSLGALDQ
Sbjct: 3 KNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRHFSQEPRKNCSLGALDQ 62
Query: 497 ACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGTVERRGAMGIWKELFCE 556
ACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGTVERRGAMGIWKELFCE
Sbjct: 63 ACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGTVERRGAMGIWKELFCE 122
Query: 557 LSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDW 616
LSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDW
Sbjct: 123 LSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDW 182
Query: 617 LDRVREALQKVRPQQEDEWVNVQYPDQPEEPPEAPQGCLSPSDLLSEPAALQGTQFDWSS 676
LD VREALQKVRPQQEDEWVNVQY DQPEEPPEAPQGCLSPSDLLSEPAALQGTQ DWSS
Sbjct: 183 LDLVREALQKVRPQQEDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSS 242
Query: 677 AQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILP 736
AQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILP
Sbjct: 243 AQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILP 302
Query: 737 DTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLDEN 796
DTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLDEN
Sbjct: 303 DTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLDEN 362
Query: 797 CQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYC 856
CQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYC
Sbjct: 363 CQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYC 422
Query: 857 DICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMH 916
DICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMH
Sbjct: 423 DICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMH 482
Query: 917 LIGRRREQLKLLGDYLGLCRSGALKELSKRLNHRNYLLESPHRFSVA------------D 964
LIGRRREQLKLLGDYLGLCRSGALKELSKR + L++ A
Sbjct: 483 LIGRRREQLKLLGDYLGLCRSGALKELSKRAGPESASLKTASSILAAVLPEPGLLRARVC 542
Query: 965 LQQIADGVYEGFLKALIE---FASQHVYHCDLCTQRGFICQICQHHDIIFPFEFDTTVRC 1021
L+Q+ G +G +K+L + V CT Q C V C
Sbjct: 543 LEQVPRG-SQGVVKSLGSGGALSPSLVKEPGTCTG----MQTCVD---------QMPVGC 588
Query: 1022 AECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA 1056
AECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA
Sbjct: 589 AECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA 623
>gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo
sapiens]
Length = 528
Score = 1033 bits (2671), Expect = 0.0
Identities = 505/519 (97%), Positives = 509/519 (98%)
Query: 527 GLSNPFRGLMKLGTVERRGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG 586
GLSNPF+GLMKLGTVER+GAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG
Sbjct: 10 GLSNPFQGLMKLGTVERQGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG 69
Query: 587 PAHSDGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVRPQQEDEWVNVQYPDQPEE 646
PAHSDGRFELVFSGKKLALRASSQDEAEDWLD VREALQKVRPQQEDEWVNVQY DQPEE
Sbjct: 70 PAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQEDEWVNVQYSDQPEE 129
Query: 647 PPEAPQGCLSPSDLLSEPAALQGTQFDWSSAQVPEPDAIKESLLYLYMDRTWMPYIFSLS 706
PPEAPQGCLSPSDLLSEPAALQGTQ DWSSAQVPE DAIKESLLYLYMDRTWMPYIFSL
Sbjct: 130 PPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPELDAIKESLLYLYMDRTWMPYIFSLP 189
Query: 707 LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA 766
LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA
Sbjct: 190 LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA 249
Query: 767 LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS 826
LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS
Sbjct: 250 LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS 309
Query: 827 QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA 886
QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA
Sbjct: 310 QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA 369
Query: 887 LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKR 946
LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGR REQLKLLGDYLGLCRSGALKELSKR
Sbjct: 370 LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELSKR 429
Query: 947 LNHRNYLLESPHRFSVADLQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICQH 1006
LNHRNYLLESPHRF VADL+QIAD VYEGFLKALIEFASQHVYHCDLCTQR FICQICQH
Sbjct: 430 LNHRNYLLESPHRFRVADLRQIADEVYEGFLKALIEFASQHVYHCDLCTQRSFICQICQH 489
Query: 1007 HDIIFPFEFDTTVRCAECKTVFHQSCQAVVKKGCPRCAR 1045
HDIIFP EFDTTVRCA+CKTVFHQSCQAVVKKGCPRCAR
Sbjct: 490 HDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR 528
>gi|122937347 pleckstrin homology domain containing, family M, member
3 [Homo sapiens]
Length = 761
Score = 264 bits (674), Expect = 4e-70
Identities = 176/545 (32%), Positives = 275/545 (50%), Gaps = 37/545 (6%)
Query: 532 FRGLMKLGTVE-RRGAMGIWKELFCELSPLEFRLYL--SNEEHTCVENCSLLRCESVGP- 587
F ++K G +E R+ W+ + ELSP Y S+ L +S+
Sbjct: 209 FPNILKKGYLEIRKDHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVL 268
Query: 588 AHSDGRF--ELVFSGKKLALRASSQDEAEDWLDRVREALQKVRP----QQEDEWVNV--- 638
+ + R +++ +L L+A S EA DW ++ E + P +Q + ++
Sbjct: 269 GNLEARMVDTVLYDNTQLQLKAESPWEALDWGQKLWEVVHAAVPGYMGRQNELTISPGLG 328
Query: 639 QYPD--QPEEPPEAPQGCLSPSDLLSEPAALQGTQFDWSSAQVPEPDAIKESLLY-LYMD 695
+ D Q + G L PS +L Q + +K LY L +
Sbjct: 329 HHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQ--------------NILKSGTLYRLTVQ 374
Query: 696 RTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVL 755
W + F LS L F+ ++ S+ V+ + D G S F++I + VL
Sbjct: 375 NNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVL 434
Query: 756 KLQAGNAEEAALWRDLVRKVLASYLETAEE--AVTLGGS-LDENCQEVLKFATREN--GF 810
+L+A + A W + + K+ A+ ++E+ VTL D+ L+ R++
Sbjct: 435 RLRAETRQRAQEWMEAL-KIAANVARSSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTS 493
Query: 811 LLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPAR 870
L L + +E+GL +Q CAGC R IG S + K+C +SG YYC CH DD+ +IPAR
Sbjct: 494 FLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPAR 553
Query: 871 IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGD 930
I+HNWD +K + +QA +FL + +PLI++Q NA LY H E + + R R++LK L
Sbjct: 554 IVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRA 613
Query: 931 YLGLCRSGALKELSKRLNHRNYLLESPHRFSVADLQQIADGVYEGFLKALIEFASQHVYH 990
YL CR+ ++L +R+ R YLL+ H +S+ADLQQ+ +G FL +I+FA+ HVY
Sbjct: 614 YLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYS 673
Query: 991 CDLCTQRGFICQICQHHDIIFPFEFDTTVRCAECKTVFHQSCQAVVKKGCPRCARRRKYQ 1050
C LC+Q+GFIC+IC + +I++PFE +T RC C VFH C+ CPRC RR +
Sbjct: 674 CSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKE-KSVPCPRCVRRELQK 732
Query: 1051 EQNIF 1055
+Q F
Sbjct: 733 KQKSF 737
>gi|46447820 differentially expressed in FDCP 8 isoform 1 [Homo
sapiens]
Length = 512
Score = 161 bits (407), Expect = 3e-39
Identities = 82/246 (33%), Positives = 137/246 (55%), Gaps = 5/246 (2%)
Query: 813 QYLVAIPMEKGLDSQGCFCAGCSRQIGFSFV--RPKLCAFSGLYYCDICHQDDASVIPAR 870
+Y + I E GLDSQ CA C I V + C ++G YYC CH +D +VIPAR
Sbjct: 260 EYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPAR 319
Query: 871 IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGD 930
++HNWD R + R ++++L + ++P++ L+ +N L+ +VE + I + R+ + L+
Sbjct: 320 VVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKP 379
Query: 931 YLGLCRSGALKELSKRLNHRNYLLESPHRFSVADLQQIADGVYEGFLKALIEFASQHV-Y 989
Y CR L +L R + +E+ +SV DL + G L + ++H+
Sbjct: 380 YFITCREAMEARLLLQLQDRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKL 439
Query: 990 HCDLCTQRGFICQICQHHDIIFPFEFDTTVRCAECKTVFHQSCQAVVKKGCPRCARRRKY 1049
C+ C +GF+C++C+ D++FPF+ T+V CA+C VFH+ C CP+CA R
Sbjct: 440 DCERCQAKGFVCELCREGDVLFPFDSHTSV-CADCSAVFHRDCYYDNSTTCPKCA-RLSL 497
Query: 1050 QEQNIF 1055
++Q++F
Sbjct: 498 RKQSLF 503
>gi|156151402 hypothetical protein LOC80183 [Homo sapiens]
Length = 662
Score = 155 bits (391), Expect = 2e-37
Identities = 98/284 (34%), Positives = 142/284 (50%), Gaps = 21/284 (7%)
Query: 784 EEAVTLGGSLDENCQEVLKFATRENG--------FLLQYLVAIPMEKGL--DSQGCFCAG 833
EE V N + +KF +R G F + + + P+++ L +Q FCAG
Sbjct: 377 EECVRKDFESSMNVVQEIKFKSRIRGTEDWAPPRFQIIFNIHPPLKRDLVVAAQNFFCAG 436
Query: 834 CSRQIGFSFV-RPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQ 892
C + FV R + C + G Y+CD CH S IPARI+ WD K + + + L
Sbjct: 437 CGTPVEPKFVKRLRYCEYLGKYFCDCCHSYAESCIPARILMMWDFKKYYVSNFSKQLLDS 496
Query: 893 IRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCR--SGALKELSKRLNHR 950
I QP+ NL + SLY + + + +EQL + L CR + ALKE + H
Sbjct: 497 IWHQPIFNLLSIGQSLYAKAKELDRVKEIQEQLFHIKKLLKTCRFANSALKEFEQVPGH- 555
Query: 951 NYLLESPHRFSVADLQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICQHHDII 1010
L + H FS+ DL +I G+ LK +++ + HV C+LC +GFIC+ CQ+ +I
Sbjct: 556 --LTDELHLFSLEDLVRIKKGLLAPLLKDILKASLAHVAGCELCQGKGFICEFCQNTTVI 613
Query: 1011 FPFEFDTTVRCAECKTVFHQSCQAVVKKGCPRCAR---RRKYQE 1051
FPF+ T RC+ C+ FH+ C CPRCAR RRK E
Sbjct: 614 FPFQTATCRRCSACRACFHKQC--FQSSECPRCARITARRKLLE 655
>gi|224548938 hypothetical protein LOC9711 isoform 1 [Homo sapiens]
Length = 927
Score = 129 bits (324), Expect = 1e-29
Identities = 76/225 (33%), Positives = 114/225 (50%), Gaps = 9/225 (4%)
Query: 831 CAGCSRQIGFSFV-RPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKF 889
CAGC + ++ R + C + G Y+C CH++ IP+R++ WD +K + +
Sbjct: 676 CAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDL 735
Query: 890 LTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKRLNH 949
L +I PL N+Q +N++LY V+ ++ + R QL + + CR KEL +
Sbjct: 736 LIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCR--LAKELLDSFDT 793
Query: 950 -RNYLLESPHRFSVADLQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICQHH- 1007
+L E H +S+ DL G L L + HV C LC +GFIC+ CQ+
Sbjct: 794 VPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNED 853
Query: 1008 DIIFPFEFDTTVRCAECKTVFHQSCQAVVKKG-CPRCARRRKYQE 1051
DIIFPFE C ECK +H++C K G CPRC R + +E
Sbjct: 854 DIIFPFELHKCRTCEECKACYHKAC---FKSGSCPRCERLQARRE 895
>gi|150456467 hypothetical protein LOC9711 isoform 2 [Homo sapiens]
Length = 972
Score = 129 bits (324), Expect = 1e-29
Identities = 76/225 (33%), Positives = 114/225 (50%), Gaps = 9/225 (4%)
Query: 831 CAGCSRQIGFSFV-RPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKF 889
CAGC + ++ R + C + G Y+C CH++ IP+R++ WD +K + +
Sbjct: 721 CAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDL 780
Query: 890 LTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKRLNH 949
L +I PL N+Q +N++LY V+ ++ + R QL + + CR KEL +
Sbjct: 781 LIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCR--LAKELLDSFDT 838
Query: 950 -RNYLLESPHRFSVADLQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICQHH- 1007
+L E H +S+ DL G L L + HV C LC +GFIC+ CQ+
Sbjct: 839 VPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNED 898
Query: 1008 DIIFPFEFDTTVRCAECKTVFHQSCQAVVKKG-CPRCARRRKYQE 1051
DIIFPFE C ECK +H++C K G CPRC R + +E
Sbjct: 899 DIIFPFELHKCRTCEECKACYHKAC---FKSGSCPRCERLQARRE 940
>gi|116292170 RUN domain containing 2A [Homo sapiens]
Length = 375
Score = 94.4 bits (233), Expect = 5e-19
Identities = 64/208 (30%), Positives = 99/208 (47%), Gaps = 10/208 (4%)
Query: 20 KKLVGSVKALQKQYVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKHIRAEAGGKRKKSA 79
++L+ +VK Q ++ + + D +C+ EAV HGL A K++A
Sbjct: 15 ERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLKRSRGLALTAAAIKQAA 74
Query: 80 H--QKPLPQPVFWPLLKAVTHKHIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKL 137
K +PVFW +K V +KH + L + +DVGR RAWLR ALN+ +E YL +
Sbjct: 75 GFASKTETEPVFWYYVKEVLNKHELQRFYSLRHIASDVGRGRAWLRCALNEHSLERYLHM 134
Query: 138 LLQEQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYKSAILNEWTLTPLALSG 197
LL ++ RL +Y+ + + D E L + GL S+ F ++ + LN S
Sbjct: 135 LLADRCRLSTFYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNKDLN-------GQSK 187
Query: 198 LCP-LSELDPLSTSGAELQRKESLDSIS 224
P +S+L ST KES +S
Sbjct: 188 FAPTVSDLLKESTQNVTSLLKESTQGVS 215
>gi|221139728 pleckstrin homology domain containing, family M (with
RUN domain) member 2 [Homo sapiens]
Length = 1019
Score = 69.3 bits (168), Expect = 2e-11
Identities = 56/211 (26%), Positives = 92/211 (43%), Gaps = 31/211 (14%)
Query: 25 SVKALQKQYVSLDT---VVTSEDGDANTMCSALEAVFIHGLHAKHIRAEAGGKRKKSAHQ 81
SVK LQ + + + + + D +C L+ ++GL +G
Sbjct: 17 SVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQD----LSSG--------- 63
Query: 82 KPLPQPVFWPLLKAVTHKHIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQE 141
+W L+ T + I ++E L V T++GR RAWL LALN+ +E YL+L +
Sbjct: 64 -------YWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQEN 116
Query: 142 QARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYKSAILNEWTLTPLALSGLCPL 201
LH+YY AL+ + L+ + GL + FEL + L+ L P P
Sbjct: 117 LGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLD---LAPYMPDYYKPQ 173
Query: 202 SELD-----PLSTSGAELQRKESLDSISHSS 227
LD P S G++ S +S++ ++
Sbjct: 174 YLLDFEDRLPSSVHGSDSLSLNSFNSVTSTN 204
>gi|7662352 RUN and FYVE domain containing 3 isoform 2 [Homo
sapiens]
Length = 469
Score = 58.2 bits (139), Expect = 4e-08
Identities = 48/167 (28%), Positives = 73/167 (43%), Gaps = 20/167 (11%)
Query: 25 SVKALQKQYVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKHIRAEAGGKRKKSAHQKPL 84
S+K L + ++L + S+ +E HGL AK G+ K
Sbjct: 79 SIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFL---GQNKS------- 128
Query: 85 PQPVFWPLLKAVTH-----KHIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLL 139
FW L+ V I + ++ L + T VGR RAWLRLAL + Y+K L+
Sbjct: 129 ----FWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALI 184
Query: 140 QEQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYKSAILN 186
++ L E+Y+P AL+ + EEG + L GL + K L+
Sbjct: 185 NKKELLSEFYEPNALMME-EEGAIIAGLLVGLNVIDANFCMKGEDLD 230
>gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 620
Score = 58.2 bits (139), Expect = 4e-08
Identities = 48/167 (28%), Positives = 73/167 (43%), Gaps = 20/167 (11%)
Query: 25 SVKALQKQYVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKHIRAEAGGKRKKSAHQKPL 84
S+K L + ++L + S+ +E HGL AK G+ K
Sbjct: 79 SIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFL---GQNKS------- 128
Query: 85 PQPVFWPLLKAVTH-----KHIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLL 139
FW L+ V I + ++ L + T VGR RAWLRLAL + Y+K L+
Sbjct: 129 ----FWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALI 184
Query: 140 QEQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYKSAILN 186
++ L E+Y+P AL+ + EEG + L GL + K L+
Sbjct: 185 NKKELLSEFYEPNALMME-EEGAIIAGLLVGLNVIDANFCMKGEDLD 230
>gi|195220720 RUN and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 58.2 bits (139), Expect = 4e-08
Identities = 48/167 (28%), Positives = 73/167 (43%), Gaps = 20/167 (11%)
Query: 25 SVKALQKQYVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKHIRAEAGGKRKKSAHQKPL 84
S+K L + ++L + S+ +E HGL AK G+ K
Sbjct: 139 SIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFL---GQNKS------- 188
Query: 85 PQPVFWPLLKAVTH-----KHIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLL 139
FW L+ V I + ++ L + T VGR RAWLRLAL + Y+K L+
Sbjct: 189 ----FWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALI 244
Query: 140 QEQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYKSAILN 186
++ L E+Y+P AL+ + EEG + L GL + K L+
Sbjct: 245 NKKELLSEFYEPNALMME-EEGAIIAGLLVGLNVIDANFCMKGEDLD 290
>gi|122891862 DENN/MADD domain containing 5B [Homo sapiens]
Length = 1274
Score = 56.2 bits (134), Expect = 2e-07
Identities = 41/146 (28%), Positives = 68/146 (46%), Gaps = 19/146 (13%)
Query: 49 TMCSALEAVFIHGLHAKHIRA-------EAGGKRKKSAHQKPLP-----------QPVFW 90
++C LE ++ HGL K ++ + + +K H P V
Sbjct: 780 SLCDLLERIWSHGLQVKQGKSALWSHLIQFQDREEKQEHLAESPVALGPERRKSDSGVML 839
Query: 91 PLLKAVTHKHIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQEQARLHEYYQ 150
P L+ V+ + +++++ + TDVGR RAW+RL+L L+ +LK LL Q + Y+
Sbjct: 840 PTLR-VSLIQDMRHIQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYK 898
Query: 151 PTALLRDAEEGEFLLSFLQGLTSLSF 176
A LR EE E L L L ++ +
Sbjct: 899 RYAFLRCEEEREQFLYHLLSLNAVDY 924
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 54.7 bits (130), Expect = 5e-07
Identities = 55/192 (28%), Positives = 87/192 (45%), Gaps = 14/192 (7%)
Query: 101 IISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQEQARLHEYYQPTALLRDAEE 160
I + + +L + T VGR RAWL LAL + YLK+L+ + L E+Y+P AL+ + EE
Sbjct: 82 IATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMME-EE 140
Query: 161 GEFLLSFLQGLTSLSFELSYKSAILNEWTLTPLALSGLCPLSELDPLSTSGAELQRKESL 220
G ++ L GL L L K L+ L + +LD G E +R
Sbjct: 141 GMVIVGLLVGLNVLDANLCLKGEDLDSQVGVIDFSLYLKDVQDLD----GGKEHER--IT 194
Query: 221 DSISHSSGSEDIEVHHS------GHKIRRNQKLTASSLSLDTASSSQLSCSLNSDSCLLQ 274
D + + E++ H S KI +K T S L + ++++ CSL + L+
Sbjct: 195 DVLDQKNYVEELNRHLSCTVGDLQTKIDGLEK-TNSKLQEELSAATDRICSLQEEQQQLR 253
Query: 275 ENGSKSPDHCEE 286
E + E+
Sbjct: 254 EQNELIRERSEK 265
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 54.7 bits (130), Expect = 5e-07
Identities = 55/192 (28%), Positives = 87/192 (45%), Gaps = 14/192 (7%)
Query: 101 IISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQEQARLHEYYQPTALLRDAEE 160
I + + +L + T VGR RAWL LAL + YLK+L+ + L E+Y+P AL+ + EE
Sbjct: 82 IATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMME-EE 140
Query: 161 GEFLLSFLQGLTSLSFELSYKSAILNEWTLTPLALSGLCPLSELDPLSTSGAELQRKESL 220
G ++ L GL L L K L+ L + +LD G E +R
Sbjct: 141 GMVIVGLLVGLNVLDANLCLKGEDLDSQVGVIDFSLYLKDVQDLD----GGKEHER--IT 194
Query: 221 DSISHSSGSEDIEVHHS------GHKIRRNQKLTASSLSLDTASSSQLSCSLNSDSCLLQ 274
D + + E++ H S KI +K T S L + ++++ CSL + L+
Sbjct: 195 DVLDQKNYVEELNRHLSCTVGDLQTKIDGLEK-TNSKLQEELSAATDRICSLQEEQQQLR 253
Query: 275 ENGSKSPDHCEE 286
E + E+
Sbjct: 254 EQNELIRERSEK 265
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 54.7 bits (130), Expect = 5e-07
Identities = 55/192 (28%), Positives = 87/192 (45%), Gaps = 14/192 (7%)
Query: 101 IISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQEQARLHEYYQPTALLRDAEE 160
I + + +L + T VGR RAWL LAL + YLK+L+ + L E+Y+P AL+ + EE
Sbjct: 190 IATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMME-EE 248
Query: 161 GEFLLSFLQGLTSLSFELSYKSAILNEWTLTPLALSGLCPLSELDPLSTSGAELQRKESL 220
G ++ L GL L L K L+ L + +LD G E +R
Sbjct: 249 GMVIVGLLVGLNVLDANLCLKGEDLDSQVGVIDFSLYLKDVQDLD----GGKEHER--IT 302
Query: 221 DSISHSSGSEDIEVHHS------GHKIRRNQKLTASSLSLDTASSSQLSCSLNSDSCLLQ 274
D + + E++ H S KI +K T S L + ++++ CSL + L+
Sbjct: 303 DVLDQKNYVEELNRHLSCTVGDLQTKIDGLEK-TNSKLQEELSAATDRICSLQEEQQQLR 361
Query: 275 ENGSKSPDHCEE 286
E + E+
Sbjct: 362 EQNELIRERSEK 373
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 50.1 bits (118), Expect = 1e-05
Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 99 KHIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQEQARLHEYYQPTALLRDA 158
+ I + + L + T +GR RAWLRLAL M YL+ L+ ++ L E+Y+ AL+ +
Sbjct: 121 EEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMME- 179
Query: 159 EEGEFLLSFLQGLTSLSFELSYKSAILN 186
EEG ++ L GL + L K L+
Sbjct: 180 EEGAVIVGLLVGLNVIDANLCVKGEDLD 207
>gi|44889475 RAB6 interacting protein 1 [Homo sapiens]
Length = 1287
Score = 46.6 bits (109), Expect = 1e-04
Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 35/148 (23%)
Query: 49 TMCSALEAVFIHGLHAKHIRAE---------------------------AGGKRKKSAHQ 81
++C LE ++ HGL K ++ +R+KS
Sbjct: 795 SLCDLLERIWSHGLQVKQGKSALWSHLLHYQDNRQRKLTSGSLSTSGILLDSERRKSDAS 854
Query: 82 KPLPQPVFWPLLKAVTHKHIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQE 141
+P P+ L++ + H I E + TDVG+ RAW+RL++ L+ +LK LL +
Sbjct: 855 SLMP-PLRISLIQDMRHIQNIGE------IKTDVGKARAWVRLSMEKKLLSRHLKQLLSD 907
Query: 142 QARLHEYYQPTALLR-DAEEGEFLLSFL 168
+ Y+ A LR D E+ +FL L
Sbjct: 908 HELTKKLYKRYAFLRCDDEKEQFLYHLL 935
>gi|197304746 RUN domain containing 3B isoform c [Homo sapiens]
Length = 407
Score = 42.7 bits (99), Expect = 0.002
Identities = 53/257 (20%), Positives = 105/257 (40%), Gaps = 19/257 (7%)
Query: 89 FWPLLKAVTHK---HIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQEQARL 145
FW ++ K + I +E++ V++ + RAW+R+AL + + Y+ L++
Sbjct: 93 FWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTT 152
Query: 146 HEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYKS--------AILNEWTLTPLALSG 197
+Y+ A++ EE L L GL ++ F K A+++ S
Sbjct: 153 RRFYEDGAIVL-GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSS 211
Query: 198 LCPLSELDPLSTSGAELQRKESLDSISHSSGSEDIEVHHSGHKIRRNQKLTASSL----S 253
S+ + L T G+ + +++ ++ + ++++ +LT
Sbjct: 212 DSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEE 271
Query: 254 LDTASSSQLSCSLNSDSCLLQENGSKSPDHCEEPMSCDSDLGTANAE-DSDRSLQEVLLE 312
L +QLS S++ + LLQ H E + + + S +SL ++ E
Sbjct: 272 LLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAE 331
Query: 313 FSKAQVNSVPTNGLSQE 329
S +Q + P G SQE
Sbjct: 332 VSLSQTSLDP--GQSQE 346
>gi|19923090 RUN domain containing 3B isoform a [Homo sapiens]
Length = 473
Score = 42.4 bits (98), Expect = 0.002
Identities = 37/178 (20%), Positives = 73/178 (41%), Gaps = 17/178 (9%)
Query: 17 VIKKKLVGSVKALQKQYVSLDTVVTSEDG--DANTMCSALEAVFIHGLHA--------KH 66
V ++ L+ + K + T +D + N + LE + H L H
Sbjct: 31 VERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKEISQSCRWLAH 90
Query: 67 IRAEAGGKRKKSAHQKPLPQPVFWPLLKAVTHK---HIISELEHLTFVNTDVGRCRAWLR 123
++ G+ ++ P FW ++ K + I +E++ V++ + RAW+R
Sbjct: 91 LQIPLQGQVTWFGYESPRS---FWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIR 147
Query: 124 LALNDGLMECYLKLLLQEQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYK 181
+AL + + Y+ L++ +Y+ A++ EE L L GL ++ F K
Sbjct: 148 VALMEKHLSEYISTALRDFKTTRRFYEDGAIVL-GEEANMLAGMLLGLNAIDFSFCLK 204
>gi|197304744 RUN domain containing 3B isoform b [Homo sapiens]
Length = 456
Score = 41.6 bits (96), Expect = 0.004
Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 4/96 (4%)
Query: 89 FWPLLKAVTHK---HIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQEQARL 145
FW ++ K + I +E++ V++ + RAW+R+AL + + Y+ L++
Sbjct: 93 FWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTT 152
Query: 146 HEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYK 181
+Y+ A++ EE L L GL ++ F K
Sbjct: 153 RRFYEDGAIVL-GEEANMLAGMLLGLNAIDFSFCLK 187
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 39.7 bits (91), Expect = 0.015
Identities = 40/158 (25%), Positives = 59/158 (37%), Gaps = 17/158 (10%)
Query: 222 SISHSSGSEDIEVHHSGHKIRRNQKLTASSLSLDTASSSQLSCSLNSDSCLLQENGSKSP 281
S + SS S S + ++SS S ++SSS S S +S S + S S
Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670
Query: 282 DHCEEPMSCDSDLGTANAEDSDRSLQEVLLEFSKAQVNSVPTNGLSQETEIPTPQASLSL 341
+E SC SD A A + S Q L + Q + S + P PQ
Sbjct: 2671 STTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAP- 2729
Query: 342 HGLNTSTYLHCEAPAEPLPAQAASGT------QDGVHV 373
P +PL +A +G ++GVH+
Sbjct: 2730 ----------PPQPTQPLQPKAQAGAKSRPKKREGVHL 2757
Score = 38.1 bits (87), Expect = 0.044
Identities = 45/187 (24%), Positives = 66/187 (35%), Gaps = 9/187 (4%)
Query: 202 SELDPLSTSGAELQRKESLDSISHSSGSEDIEVHHSGHKIRRNQKLT-ASSLSLDTASSS 260
SE S+SG+ S S S + G E+ + + G + + ASS + ASSS
Sbjct: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616
Query: 261 QLSCSLNSDSCLLQENGSKSPDHCEEPMSCDSDLGTANAEDSDRSLQEVLLEFSKAQVNS 320
S S +S S + S S S S ++++ S S S +
Sbjct: 2617 SSSSSSSSSSS--SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD 2674
Query: 321 VPTNGLSQETEIPTPQASLSLHGLNTSTYLHCEAPAEPLPAQAASGTQDGVHVQEPRPQA 380
++ S + P P A S + A P S G P+PQA
Sbjct: 2675 EDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARP------SAHSPGKKTPAPQPQA 2728
Query: 381 PSPLDLQ 387
P P Q
Sbjct: 2729 PPPQPTQ 2735
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 39.3 bits (90), Expect = 0.020
Identities = 72/324 (22%), Positives = 108/324 (33%), Gaps = 29/324 (8%)
Query: 207 LSTSGAELQRKESLDSISHSSGSEDIEVHHSGHKIRRNQKLTASSLSLDTASSSQLSCSL 266
L + G E ++ S + ED E + +K T S D S S CSL
Sbjct: 961 LDSEGEEASQESSSEK-DEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSL 1019
Query: 267 NSDSCLLQENGSKSPDHCEEPMSCDSDLGTANAEDSDRSLQEVLLEFSKAQVNSVPTNGL 326
+DS EN S S S S ++++ S S E E + +
Sbjct: 1020 YADSD--GENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSA 1077
Query: 327 S---QETEIPTPQASLSLHGLNTSTYLHCEAPAEPLPAQAASGTQDGVHVQE-------- 375
S +E +PTP A + + +P PLP Q AS + +E
Sbjct: 1078 SPPPREVPVPTP-APVEV----PVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLR 1132
Query: 376 -PRPQAPSPLDLQQPVESTSGQQPSSTVSETAREVGQGNGLQKAQAHDGAGLKLVVSSPT 434
P P A P +P E S P + R+ + ++ A + +
Sbjct: 1133 PPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFP 1192
Query: 435 SPKNKSWISEDDFYRPSREQPLESAS------DHPIASYRGTPGSRPGLHRHFSQEPRKN 488
P ++ + R R PL+ AS + R G R L EP
Sbjct: 1193 GPASRK--APRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTE 1250
Query: 489 CSLGALDQACVPSPGRRQAQAAPS 512
L L + +P RR A P+
Sbjct: 1251 VDLAVLADLAL-TPARRGLPALPA 1273
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 39.3 bits (90), Expect = 0.020
Identities = 55/223 (24%), Positives = 76/223 (34%), Gaps = 28/223 (12%)
Query: 307 QEVLLEFSKAQVNSVPTNGLSQETEIPTPQASLSLHGLNTSTYLHCEAPAEPL-PAQAAS 365
+EV A + S P N +E E +A + + H E+ + L P +
Sbjct: 408 EEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGIT 467
Query: 366 GTQDGVHVQEPRPQAPSPLDLQQPVESTSGQQPSSTVSETAREVGQGNGLQKAQAHDGAG 425
T + P P+APS L S +P S A V L A AG
Sbjct: 468 PTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSV---ESLSSESASQTAG 524
Query: 426 LKLV-------------VSSPTSPKNKSWISEDDFYRPSREQPLESASDHPIASYRGTPG 472
+L+ V +P +P N +S + S E P AS PG
Sbjct: 525 AELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQAS----PG 580
Query: 473 SRPGLHRHFSQEPRKNCS-------LGALDQACVPSPGRRQAQ 508
P +P K CS L D++ VPSPG Q
Sbjct: 581 LAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQ 623
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 38.9 bits (89), Expect = 0.026
Identities = 44/171 (25%), Positives = 63/171 (36%), Gaps = 17/171 (9%)
Query: 357 EPLPAQAASGTQDGVHVQEPRPQAPS------PLDLQQPVESTSGQQPSSTVSETAREVG 410
+P AA+G V +P PQAP PL LQQP QQP + A
Sbjct: 604 QPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQP----QAQQPPQAPTPQAAAPP 659
Query: 411 QGNGLQKAQAHDGAGLKLVVSSPTSPKNKSWISEDDFY----RPSREQPLESASDHPIAS 466
Q Q + + K+V+ P S + +++D + +QPL + H
Sbjct: 660 QATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP 719
Query: 467 YRGTPGSRPGLHRHFSQEP-RKNCSLG--ALDQACVPSPGRRQAQAAPSQG 514
+ P P K LG A D P+P + AAP +G
Sbjct: 720 ASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKG 770
>gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform d [Homo sapiens]
Length = 1133
Score = 38.1 bits (87), Expect = 0.044
Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
Query: 527 GLSNPFRGLMKLGTVERRGAMG--IWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCES 584
G S P ++K G +++ G I+++ + L R + SN++ S+ C S
Sbjct: 75 GGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVA-CIS 133
Query: 585 VGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVR 628
A D +FE++ + + A RA S E ++W+ +++A+ + R
Sbjct: 134 HVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQR 177
>gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform a [Homo sapiens]
Length = 1205
Score = 38.1 bits (87), Expect = 0.044
Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
Query: 527 GLSNPFRGLMKLGTVERRGAMG--IWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCES 584
G S P ++K G +++ G I+++ + L R + SN++ S+ C S
Sbjct: 75 GGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVA-CIS 133
Query: 585 VGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVR 628
A D +FE++ + + A RA S E ++W+ +++A+ + R
Sbjct: 134 HVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQR 177
>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
1 isoform c [Homo sapiens]
Length = 1450
Score = 38.1 bits (87), Expect = 0.044
Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
Query: 527 GLSNPFRGLMKLGTVERRGAMG--IWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCES 584
G S P ++K G +++ G I+++ + L R + SN++ S+ C S
Sbjct: 320 GGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVA-CIS 378
Query: 585 VGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVR 628
A D +FE++ + + A RA S E ++W+ +++A+ + R
Sbjct: 379 HVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQR 422
>gi|17149830 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 1 [Homo sapiens]
Length = 759
Score = 38.1 bits (87), Expect = 0.044
Identities = 49/191 (25%), Positives = 74/191 (38%), Gaps = 17/191 (8%)
Query: 289 SCDSDL--GTANAEDSDRSLQEVLLEFSKAQVNSVPTNGLSQETEIPTPQASLSLHGLNT 346
S DSDL G ++ ++ +K Q N LS E I + +L N+
Sbjct: 415 SLDSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQKKLQ-TLQSENS 473
Query: 347 STYLHCEAPAEPLPAQAASGTQDGVH----VQEPRPQAPSPLDLQQPVESTSGQQPSSTV 402
+ L +A Q S D + + P + P+ + E+ SGQ+P +
Sbjct: 474 N--LRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMY---ETGSGQKPYLPM 528
Query: 403 SETAREVGQGNGLQKAQAHDGAGLKLVVSS--PTSPKNKSWISEDDFYRPSREQPLESAS 460
E +R LQ AH G + SS P+ P SW ++ R SR LE +
Sbjct: 529 GEASRPEESRMRLQPFPAHIGRSALVTSSSSLPSFPSTLSWSRDESARRASR---LEKQN 585
Query: 461 DHPIASYRGTP 471
P + Y TP
Sbjct: 586 STPESDYDNTP 596
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,139,558
Number of Sequences: 37866
Number of extensions: 2159530
Number of successful extensions: 8338
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 156
Number of HSP's that attempted gapping in prelim test: 8113
Number of HSP's gapped (non-prelim): 390
length of query: 1056
length of database: 18,247,518
effective HSP length: 113
effective length of query: 943
effective length of database: 13,968,660
effective search space: 13172446380
effective search space used: 13172446380
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.