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Search of human proteins with 40353738
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40353738 c-Mpl binding protein isoform a [Homo sapiens]
(724 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40353738 c-Mpl binding protein isoform a [Homo sapiens] 1466 0.0
gi|40353740 c-Mpl binding protein isoform b [Homo sapiens] 1458 0.0
gi|40353736 c-Mpl binding protein isoform c [Homo sapiens] 778 0.0
gi|57634536 La ribonucleoprotein domain family, member 4B [Homo ... 421 e-117
gi|61102725 la related protein isoform 2 [Homo sapiens] 74 6e-13
gi|39725634 la related protein isoform 1 [Homo sapiens] 74 6e-13
gi|30061565 La ribonucleoprotein domain family member 2 isoform ... 69 2e-11
gi|30061569 La ribonucleoprotein domain family member 2 isoform ... 69 2e-11
gi|30061567 La ribonucleoprotein domain family member 2 isoform ... 69 2e-11
gi|109809739 La ribonucleoprotein domain family, member 7 [Homo ... 54 5e-07
gi|109809741 La ribonucleoprotein domain family, member 7 [Homo ... 54 5e-07
gi|239753842 PREDICTED: similar to hCG2040199 [Homo sapiens] 54 7e-07
gi|169166778 PREDICTED: similar to hCG2040199 [Homo sapiens] 54 7e-07
gi|169166363 PREDICTED: similar to hCG2040199 [Homo sapiens] 54 7e-07
gi|37537710 La ribonucleoprotein domain family, member 6 isoform... 45 2e-04
gi|21536423 amphiphysin isoform 2 [Homo sapiens] 45 2e-04
gi|4502081 amphiphysin isoform 1 [Homo sapiens] 45 2e-04
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 45 2e-04
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 45 2e-04
gi|10835067 autoantigen La [Homo sapiens] 40 0.006
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ... 40 0.006
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ... 40 0.006
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ... 40 0.006
gi|47578107 delangin isoform B [Homo sapiens] 37 0.049
gi|47578105 delangin isoform A [Homo sapiens] 37 0.049
gi|149944526 additional sex combs like 3 [Homo sapiens] 37 0.084
gi|4758216 dishevelled 2 [Homo sapiens] 36 0.14
gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sap... 36 0.14
gi|87162461 fragile X mental retardation 2 [Homo sapiens] 35 0.19
gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sap... 35 0.19
>gi|40353738 c-Mpl binding protein isoform a [Homo sapiens]
Length = 724
Score = 1466 bits (3795), Expect = 0.0
Identities = 724/724 (100%), Positives = 724/724 (100%)
Query: 1 MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAEL 60
MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAEL
Sbjct: 1 MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAEL 60
Query: 61 SEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLK 120
SEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLK
Sbjct: 61 SEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLK 120
Query: 121 ECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSS 180
ECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSS
Sbjct: 121 ECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSS 180
Query: 181 PMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYI 240
PMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYI
Sbjct: 181 PMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYI 240
Query: 241 TFQSDTDAQQAFKYLREEVKTFQGKPIMVRIKAINTFFAKNGYRLMDSSIYSHPIQTQAQ 300
TFQSDTDAQQAFKYLREEVKTFQGKPIMVRIKAINTFFAKNGYRLMDSSIYSHPIQTQAQ
Sbjct: 241 TFQSDTDAQQAFKYLREEVKTFQGKPIMVRIKAINTFFAKNGYRLMDSSIYSHPIQTQAQ 300
Query: 301 YASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGSFVNGFNSPGSYKTN 360
YASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGSFVNGFNSPGSYKTN
Sbjct: 301 YASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGSFVNGFNSPGSYKTN 360
Query: 361 AAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHNPTVTGH 420
AAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHNPTVTGH
Sbjct: 361 AAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHNPTVTGH 420
Query: 421 QEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLL 480
QEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLL
Sbjct: 421 QEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLL 480
Query: 481 ASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTECTSAQQL 540
ASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTECTSAQQL
Sbjct: 481 ASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTECTSAQQL 540
Query: 541 NMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRASTASPCN 600
NMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRASTASPCN
Sbjct: 541 NMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRASTASPCN 600
Query: 601 NNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTKNEDNGAPENS 660
NNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTKNEDNGAPENS
Sbjct: 601 NNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTKNEDNGAPENS 660
Query: 661 VEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFSHRAIPQGVTRRNGKEQYVPP 720
VEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFSHRAIPQGVTRRNGKEQYVPP
Sbjct: 661 VEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFSHRAIPQGVTRRNGKEQYVPP 720
Query: 721 RSPK 724
RSPK
Sbjct: 721 RSPK 724
>gi|40353740 c-Mpl binding protein isoform b [Homo sapiens]
Length = 730
Score = 1458 bits (3774), Expect = 0.0
Identities = 723/730 (99%), Positives = 723/730 (99%), Gaps = 6/730 (0%)
Query: 1 MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPE----- 55
MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPE
Sbjct: 1 MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEVSVFN 60
Query: 56 -GNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAV 114
GNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAV
Sbjct: 61 TGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAV 120
Query: 115 STEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLIL 174
STEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLIL
Sbjct: 121 STEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLIL 180
Query: 175 EVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAH 234
EVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAH
Sbjct: 181 EVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAH 240
Query: 235 NSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMVRIKAINTFFAKNGYRLMDSSIYSHP 294
NSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIM RIKAINTFFAKNGYRLMDSSIYSHP
Sbjct: 241 NSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTFFAKNGYRLMDSSIYSHP 300
Query: 295 IQTQAQYASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGSFVNGFNSP 354
IQTQAQYASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGSFVNGFNSP
Sbjct: 301 IQTQAQYASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGSFVNGFNSP 360
Query: 355 GSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHN 414
GSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHN
Sbjct: 361 GSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHN 420
Query: 415 PTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPT 474
PTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPT
Sbjct: 421 PTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPT 480
Query: 475 PKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTEC 534
PKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTEC
Sbjct: 481 PKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTEC 540
Query: 535 TSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRAS 594
TSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRAS
Sbjct: 541 TSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRAS 600
Query: 595 TASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTKNEDN 654
TASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTKNEDN
Sbjct: 601 TASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTKNEDN 660
Query: 655 GAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFSHRAIPQGVTRRNGK 714
GAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFSHRAIPQGVTRRNGK
Sbjct: 661 GAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFSHRAIPQGVTRRNGK 720
Query: 715 EQYVPPRSPK 724
EQYVPPRSPK
Sbjct: 721 EQYVPPRSPK 730
>gi|40353736 c-Mpl binding protein isoform c [Homo sapiens]
Length = 653
Score = 778 bits (2009), Expect = 0.0
Identities = 385/386 (99%), Positives = 386/386 (100%)
Query: 339 LAPFPNGSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDG 398
+APFPNGSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDG
Sbjct: 268 MAPFPNGSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDG 327
Query: 399 QLNRYSSRNFPAERHNPTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDD 458
QLNRYSSRNFPAERHNPTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDD
Sbjct: 328 QLNRYSSRNFPAERHNPTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDD 387
Query: 459 RISRPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNE 518
RISRPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNE
Sbjct: 388 RISRPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNE 447
Query: 519 ELTISCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQT 578
ELTISCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQT
Sbjct: 448 ELTISCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQT 507
Query: 579 TIPVSPPSTTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPL 638
TIPVSPPSTTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPL
Sbjct: 508 TIPVSPPSTTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPL 567
Query: 639 RELRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQ 698
RELRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQ
Sbjct: 568 RELRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQ 627
Query: 699 FSHRAIPQGVTRRNGKEQYVPPRSPK 724
FSHRAIPQGVTRRNGKEQYVPPRSPK
Sbjct: 628 FSHRAIPQGVTRRNGKEQYVPPRSPK 653
Score = 545 bits (1404), Expect = e-155
Identities = 271/287 (94%), Positives = 274/287 (95%), Gaps = 3/287 (1%)
Query: 1 MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAEL 60
MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAEL
Sbjct: 1 MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAEL 60
Query: 61 SEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLK 120
SEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLK
Sbjct: 61 SEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLK 120
Query: 121 ECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSS 180
ECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSS
Sbjct: 121 ECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSS 180
Query: 181 PMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYI 240
PMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYI
Sbjct: 181 PMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYI 240
Query: 241 TFQSDTDAQQAFKYLREEVKTFQGKPIMVRI---KAINTFFAKNGYR 284
TFQSDTDAQQAFKYLREEVKTFQGKPIM +N F + Y+
Sbjct: 241 TFQSDTDAQQAFKYLREEVKTFQGKPIMAPFPNGSFVNGFNSPGSYK 287
>gi|57634536 La ribonucleoprotein domain family, member 4B [Homo
sapiens]
Length = 738
Score = 421 bits (1081), Expect = e-117
Identities = 282/744 (37%), Positives = 404/744 (54%), Gaps = 83/744 (11%)
Query: 9 ASKGTGLNPNAKVWQEIAPG-NTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKE 67
A+K + LNPNA+VW AP + +A+ G ++W E+A ++ + D +
Sbjct: 50 ATKVSELNPNAEVWG--APVLHLEASSAADGVSAAWEEVAGHHADRGPQGSDANGDGDQG 107
Query: 68 YEVMYSSSCETTRNTTGIEESTDGMILGPEDLSY--QIYDVSGESNSAVSTEDLKECLKK 125
+E +++ + + + + + LGP + + + G + S ED +E LKK
Sbjct: 108 HE---NAALPDPQESDPAD--MNALALGPSEYDSLPENSETGGNESQPDSQEDPREVLKK 162
Query: 126 QLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSSPMVQV 185
LEFC SRENL+ D+YLISQMDSDQ++PI TVAN++ IKKL+TD DLI+EVLRS P+VQV
Sbjct: 163 TLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQV 222
Query: 186 DEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYITFQSD 245
DEKGEKVRP+ RCIVILREI E+TP+EEV+ LFK +N PK I+CEFA+N NW+ITF+++
Sbjct: 223 DEKGEKVRPNQNRCIVILREISESTPVEEVEALFKGDNLPKFINCEFAYNDNWFITFETE 282
Query: 246 TDAQQAFKYLREEVKTFQGKPIMVRIK----AINTFFAKNGYRLMDSSIYSHPIQTQAQY 301
DAQQA+KYLREEVKTFQGKPI RIK AINTF KNG+R +D S+Y+ Q +Y
Sbjct: 283 ADAQQAYKYLREEVKTFQGKPIKARIKAKAIAINTFLPKNGFRPLDVSLYA-----QQRY 337
Query: 302 ASPVFMQPVYNPHQQYSVYSIV-PQSWSPNPTPYFETPL-APFPNGSFVNGFNSPGSYKT 359
A+ + P+Y+P QQ+ +YS++ PQ+WS + Y + PL PFPN F+NGF SP ++K
Sbjct: 338 ATSFYFPPMYSPQQQFPLYSLITPQTWSATHS-YLDPPLVTPFPNTGFINGFTSP-AFKP 395
Query: 360 NAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAER-----HN 414
A+ + R + P S H+ S G G L S NF A+R +
Sbjct: 396 AASPLTSLRQYPPRSRNP---SKSHLRHAIP-SAERGPGLLESPSIFNFTADRLINGVRS 451
Query: 415 P-TVTGHQEQTYLQKETSTLQ------------VEQNGDYGRGRRTLFRGRRRREDDRIS 461
P T Q +T +Q ++ + +E + GRGR+ F R++RE+ S
Sbjct: 452 PQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKREEKFTS 511
Query: 462 RPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELT 521
S K P+P F+L S+FPPLPG++ + E + ENR+S ++ G KE+ T
Sbjct: 512 SQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKER-----T 566
Query: 522 ISCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIP 581
+S + S + S + CA T + L +D V + ++
Sbjct: 567 LSADASVNTLPVVVSREP---SVPASCAVSAT-YERSPSPAHLPDDPKVAEKQRETHSVD 622
Query: 582 VSPPSTTKPSRASTASPCNN-NINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRE 640
P A TA+ C + +N A E RK SYAE+CQ+ KEP S +QP +E
Sbjct: 623 RLP-------SALTATACKSVQVNGAAT----ELRKPSYAEICQRTSKEPPSSPLQPQKE 671
Query: 641 LRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFS 700
+ N V K E A E+ E P +++ G R+QRR
Sbjct: 672 QKPNTVGCGKEEKKLA--EPAERYREPPALKST---------------PGAPRDQRRPAG 714
Query: 701 HRAIPQGVTRRNGKEQYVPPRSPK 724
R P + +R +EQ PP+SP+
Sbjct: 715 GRPSPSAMGKRLSREQSTPPKSPQ 738
>gi|61102725 la related protein isoform 2 [Homo sapiens]
Length = 1096
Score = 73.6 bits (179), Expect = 6e-13
Identities = 44/136 (32%), Positives = 76/136 (55%), Gaps = 16/136 (11%)
Query: 98 DLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTV 157
+++Y +VS +V E LK+ +K+Q+E+ FS +NL +D +L +MD+D F+PI +
Sbjct: 382 NITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLI 441
Query: 158 ANMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKG 217
A+ ++ LTTD LI L+ S +V++ + EKVR RE PE P+ +
Sbjct: 442 ASFHRVQALTTDISLIFAALKDSKVVEIVD--EKVR---------RREEPEKWPLPPIVD 490
Query: 218 LFKSE-----NCPKVI 228
+++ NCP+ +
Sbjct: 491 YSQTDFSQLLNCPEFV 506
>gi|39725634 la related protein isoform 1 [Homo sapiens]
Length = 1019
Score = 73.6 bits (179), Expect = 6e-13
Identities = 44/136 (32%), Positives = 76/136 (55%), Gaps = 16/136 (11%)
Query: 98 DLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTV 157
+++Y +VS +V E LK+ +K+Q+E+ FS +NL +D +L +MD+D F+PI +
Sbjct: 305 NITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLI 364
Query: 158 ANMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKG 217
A+ ++ LTTD LI L+ S +V++ + EKVR RE PE P+ +
Sbjct: 365 ASFHRVQALTTDISLIFAALKDSKVVEIVD--EKVR---------RREEPEKWPLPPIVD 413
Query: 218 LFKSE-----NCPKVI 228
+++ NCP+ +
Sbjct: 414 YSQTDFSQLLNCPEFV 429
>gi|30061565 La ribonucleoprotein domain family member 2 isoform 2
[Homo sapiens]
Length = 522
Score = 68.6 bits (166), Expect = 2e-11
Identities = 48/137 (35%), Positives = 68/137 (49%), Gaps = 13/137 (9%)
Query: 56 GNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVS 115
GN L+ D Y Y E T E +T M + Q+Y V
Sbjct: 164 GNPRLNFD----YSYGYQEHGERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEAL----- 214
Query: 116 TEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILE 175
LKE +K+Q+E+ FS ENL +D +L +MD F+PI +A + ++ LTT+ +LILE
Sbjct: 215 ---LKEYIKRQIEYYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILE 271
Query: 176 VLRSSPMVQ-VDEKGEK 191
L+ S V+ VDEK K
Sbjct: 272 ALKDSTEVEIVDEKMRK 288
>gi|30061569 La ribonucleoprotein domain family member 2 isoform 3
[Homo sapiens]
Length = 358
Score = 68.6 bits (166), Expect = 2e-11
Identities = 48/137 (35%), Positives = 68/137 (49%), Gaps = 13/137 (9%)
Query: 56 GNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVS 115
GN L+ D Y Y E T E +T M + Q+Y V
Sbjct: 164 GNPRLNFD----YSYGYQEHGERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEAL----- 214
Query: 116 TEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILE 175
LKE +K+Q+E+ FS ENL +D +L +MD F+PI +A + ++ LTT+ +LILE
Sbjct: 215 ---LKEYIKRQIEYYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILE 271
Query: 176 VLRSSPMVQ-VDEKGEK 191
L+ S V+ VDEK K
Sbjct: 272 ALKDSTEVEIVDEKMRK 288
>gi|30061567 La ribonucleoprotein domain family member 2 isoform 1
[Homo sapiens]
Length = 914
Score = 68.6 bits (166), Expect = 2e-11
Identities = 48/137 (35%), Positives = 68/137 (49%), Gaps = 13/137 (9%)
Query: 56 GNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVS 115
GN L+ D Y Y E T E +T M + Q+Y V
Sbjct: 164 GNPRLNFD----YSYGYQEHGERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEAL----- 214
Query: 116 TEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILE 175
LKE +K+Q+E+ FS ENL +D +L +MD F+PI +A + ++ LTT+ +LILE
Sbjct: 215 ---LKEYIKRQIEYYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILE 271
Query: 176 VLRSSPMVQ-VDEKGEK 191
L+ S V+ VDEK K
Sbjct: 272 ALKDSTEVEIVDEKMRK 288
>gi|109809739 La ribonucleoprotein domain family, member 7 [Homo
sapiens]
Length = 582
Score = 53.9 bits (128), Expect = 5e-07
Identities = 28/73 (38%), Positives = 46/73 (63%), Gaps = 2/73 (2%)
Query: 123 LKKQLEFCFSRENLSKDLYLISQMDS--DQFIPIWTVANMEEIKKLTTDPDLILEVLRSS 180
+ KQ++F F NL KD +L Q++ D ++ I + + ++KKLTTD LI LRSS
Sbjct: 38 IAKQVDFWFGDANLHKDRFLREQIEKSRDGYVDISLLVSFNKMKKLTTDGKLIARALRSS 97
Query: 181 PMVQVDEKGEKVR 193
+V++D +G ++R
Sbjct: 98 AVVELDLEGTRIR 110
>gi|109809741 La ribonucleoprotein domain family, member 7 [Homo
sapiens]
Length = 582
Score = 53.9 bits (128), Expect = 5e-07
Identities = 28/73 (38%), Positives = 46/73 (63%), Gaps = 2/73 (2%)
Query: 123 LKKQLEFCFSRENLSKDLYLISQMDS--DQFIPIWTVANMEEIKKLTTDPDLILEVLRSS 180
+ KQ++F F NL KD +L Q++ D ++ I + + ++KKLTTD LI LRSS
Sbjct: 38 IAKQVDFWFGDANLHKDRFLREQIEKSRDGYVDISLLVSFNKMKKLTTDGKLIARALRSS 97
Query: 181 PMVQVDEKGEKVR 193
+V++D +G ++R
Sbjct: 98 AVVELDLEGTRIR 110
>gi|239753842 PREDICTED: similar to hCG2040199 [Homo sapiens]
Length = 315
Score = 53.5 bits (127), Expect = 7e-07
Identities = 31/100 (31%), Positives = 54/100 (54%), Gaps = 4/100 (4%)
Query: 99 LSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVA 158
+ Y D +G V LKEC+K+Q+E F+ EN +D +L + +PI+ +A
Sbjct: 201 MMYYYDDGTGVQVYRVEEALLKECIKRQIEHYFNAENSERDYFLRGKRGEQDSLPIFLIA 260
Query: 159 NMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKR 198
+ ++ LTT +LI E L+ S V++ EK+R +++
Sbjct: 261 GFQRVQALTT--NLITEALKDSTEVEI--MNEKMRKKNQK 296
>gi|169166778 PREDICTED: similar to hCG2040199 [Homo sapiens]
Length = 315
Score = 53.5 bits (127), Expect = 7e-07
Identities = 31/100 (31%), Positives = 54/100 (54%), Gaps = 4/100 (4%)
Query: 99 LSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVA 158
+ Y D +G V LKEC+K+Q+E F+ EN +D +L + +PI+ +A
Sbjct: 201 MMYYYDDGTGVQVYRVEEALLKECIKRQIEHYFNAENSERDYFLRGKRGEQDSLPIFLIA 260
Query: 159 NMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKR 198
+ ++ LTT +LI E L+ S V++ EK+R +++
Sbjct: 261 GFQRVQALTT--NLITEALKDSTEVEI--MNEKMRKKNQK 296
>gi|169166363 PREDICTED: similar to hCG2040199 [Homo sapiens]
Length = 315
Score = 53.5 bits (127), Expect = 7e-07
Identities = 31/100 (31%), Positives = 54/100 (54%), Gaps = 4/100 (4%)
Query: 99 LSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVA 158
+ Y D +G V LKEC+K+Q+E F+ EN +D +L + +PI+ +A
Sbjct: 201 MMYYYDDGTGVQVYRVEEALLKECIKRQIEHYFNAENSERDYFLRGKRGEQDSLPIFLIA 260
Query: 159 NMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKR 198
+ ++ LTT +LI E L+ S V++ EK+R +++
Sbjct: 261 GFQRVQALTT--NLITEALKDSTEVEI--MNEKMRKKNQK 296
>gi|37537710 La ribonucleoprotein domain family, member 6 isoform 1
[Homo sapiens]
Length = 491
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 20/111 (18%)
Query: 117 EDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQ--FIPIWTVANMEEIKKLTTDPDLIL 174
E+L + L Q+EF FS ENL KD +L+ + ++ ++ + + + +++K LT D
Sbjct: 90 EELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTA 149
Query: 175 EVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCP 225
L+ S +++++E KVR TTP+ LF +EN P
Sbjct: 150 HALKYSVVLELNEDHRKVR--------------RTTPVP----LFPNENLP 182
>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
Length = 653
Score = 45.4 bits (106), Expect = 2e-04
Identities = 40/116 (34%), Positives = 55/116 (47%), Gaps = 15/116 (12%)
Query: 583 SPPSTTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELR 642
SPP P + TASP N+ A + A PR S +K P P V P +EL+
Sbjct: 262 SPPEEPSPLPSPTASP--NHTLAPASPAPARPRSPSQT---RKGPPVPPLPKVTPTKELQ 316
Query: 643 S-NVVSPTKNEDNGAPENSVEKP--HEKPEARASK-----DYSGFRGNIIPRGAAG 690
N++S EDN PE SV P +E PE + + D+ F+ + P G+AG
Sbjct: 317 QENIISFF--EDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAG 370
>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
Length = 695
Score = 45.4 bits (106), Expect = 2e-04
Identities = 40/116 (34%), Positives = 55/116 (47%), Gaps = 15/116 (12%)
Query: 583 SPPSTTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELR 642
SPP P + TASP N+ A + A PR S +K P P V P +EL+
Sbjct: 262 SPPEEPSPLPSPTASP--NHTLAPASPAPARPRSPSQT---RKGPPVPPLPKVTPTKELQ 316
Query: 643 S-NVVSPTKNEDNGAPENSVEKP--HEKPEARASK-----DYSGFRGNIIPRGAAG 690
N++S EDN PE SV P +E PE + + D+ F+ + P G+AG
Sbjct: 317 QENIISFF--EDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAG 370
>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
Length = 2087
Score = 45.1 bits (105), Expect = 2e-04
Identities = 63/281 (22%), Positives = 107/281 (38%), Gaps = 41/281 (14%)
Query: 370 FQKNRVKPQFR----SSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHNPT-VTGHQ-EQ 423
FQ +R QF + G +H + + GD +S+ E+H+ +TG+Q Q
Sbjct: 1098 FQTDRPAEQFHLQNNAPGNCDHPLPETTATGDPT---HSNTTESGEQHHQVDLTGNQPHQ 1154
Query: 424 TYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLLASN 483
YL +GD + R T + DD +S P + ++ PT F L
Sbjct: 1155 AYL-----------SGDPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSF-LDQDQ 1202
Query: 484 FPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCP-----VPADEQTECTSAQ 538
PP S + P L D + + D + P P+ E TS
Sbjct: 1203 SPPRFYSGDQPPSYL---GASVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTA 1259
Query: 539 QLNMSTSSPCAAELTALSTTQQEKDLIED------SSVQKDGLNQTTIPVSPPSTTKPSR 592
+ T++P A+ +ST + D+ E ++ ++T P+ PP + R
Sbjct: 1260 TMTYMTTTPATAQ---MSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPPPS---QR 1313
Query: 593 ASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSV 633
++ P + AAT + L K+ + P EP ++
Sbjct: 1314 SAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPERPPEPRAM 1354
>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
Length = 1738
Score = 45.1 bits (105), Expect = 2e-04
Identities = 63/281 (22%), Positives = 107/281 (38%), Gaps = 41/281 (14%)
Query: 370 FQKNRVKPQFR----SSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHNPT-VTGHQ-EQ 423
FQ +R QF + G +H + + GD +S+ E+H+ +TG+Q Q
Sbjct: 749 FQTDRPAEQFHLQNNAPGNCDHPLPETTATGDPT---HSNTTESGEQHHQVDLTGNQPHQ 805
Query: 424 TYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLLASN 483
YL +GD + R T + DD +S P + ++ PT F L
Sbjct: 806 AYL-----------SGDPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSF-LDQDQ 853
Query: 484 FPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCP-----VPADEQTECTSAQ 538
PP S + P L D + + D + P P+ E TS
Sbjct: 854 SPPRFYSGDQPPSYL---GASVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTA 910
Query: 539 QLNMSTSSPCAAELTALSTTQQEKDLIED------SSVQKDGLNQTTIPVSPPSTTKPSR 592
+ T++P A+ +ST + D+ E ++ ++T P+ PP + R
Sbjct: 911 TMTYMTTTPATAQ---MSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPPPS---QR 964
Query: 593 ASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSV 633
++ P + AAT + L K+ + P EP ++
Sbjct: 965 SAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPERPPEPRAM 1005
>gi|10835067 autoantigen La [Homo sapiens]
Length = 408
Score = 40.4 bits (93), Expect = 0.006
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 11/103 (10%)
Query: 111 NSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQ-FIPIWTVANMEEIKKLTTD 169
N ++ + K C Q+E+ F NL +D +L Q+ D+ ++P+ + + +LTTD
Sbjct: 7 NEKMAALEAKIC--HQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTD 64
Query: 170 PDLILEVLRSS--PMVQVDEKGEKVRPSHKRCIVILREIPETT 210
++I+E L S ++++ E K+R S + +PE T
Sbjct: 65 FNVIVEALSKSKAELMEISEDKTKIRRSPS------KPLPEVT 101
>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
sapiens]
Length = 1135
Score = 40.4 bits (93), Expect = 0.006
Identities = 36/145 (24%), Positives = 60/145 (41%), Gaps = 5/145 (3%)
Query: 469 ESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMS---DVVKGVYKEKDNEELTISCP 525
E K P+PK D++ PP S P E + R S + +T++ P
Sbjct: 727 EPKEPSPKQDVVGKT-PPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAP 785
Query: 526 VPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPP 585
PA + + L ++P + S+T Q+K++ + S L T+ SP
Sbjct: 786 APAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITL-VTSTQSSPL 844
Query: 586 STTKPSRASTASPCNNNINAATAVA 610
T+ S ++ S N ++ ATA A
Sbjct: 845 VTSSGSMSTLVSSVNADLPIATASA 869
>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
sapiens]
Length = 1188
Score = 40.4 bits (93), Expect = 0.006
Identities = 36/145 (24%), Positives = 60/145 (41%), Gaps = 5/145 (3%)
Query: 469 ESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMS---DVVKGVYKEKDNEELTISCP 525
E K P+PK D++ PP S P E + R S + +T++ P
Sbjct: 752 EPKEPSPKQDVVGKT-PPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAP 810
Query: 526 VPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPP 585
PA + + L ++P + S+T Q+K++ + S L T+ SP
Sbjct: 811 APAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITL-VTSTQSSPL 869
Query: 586 STTKPSRASTASPCNNNINAATAVA 610
T+ S ++ S N ++ ATA A
Sbjct: 870 VTSSGSMSTLVSSVNADLPIATASA 894
>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
sapiens]
Length = 1160
Score = 40.4 bits (93), Expect = 0.006
Identities = 36/145 (24%), Positives = 60/145 (41%), Gaps = 5/145 (3%)
Query: 469 ESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMS---DVVKGVYKEKDNEELTISCP 525
E K P+PK D++ PP S P E + R S + +T++ P
Sbjct: 752 EPKEPSPKQDVVGKT-PPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAP 810
Query: 526 VPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPP 585
PA + + L ++P + S+T Q+K++ + S L T+ SP
Sbjct: 811 APAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITL-VTSTQSSPL 869
Query: 586 STTKPSRASTASPCNNNINAATAVA 610
T+ S ++ S N ++ ATA A
Sbjct: 870 VTSSGSMSTLVSSVNADLPIATASA 894
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 37.4 bits (85), Expect = 0.049
Identities = 81/369 (21%), Positives = 148/369 (40%), Gaps = 69/369 (18%)
Query: 266 PIMVRIKAINTFFAKNG-----YRLMDSSIYSHPIQTQAQYASPVFMQPV--YNPHQQYS 318
P + R K++ + ++G Y+L +S++S P + Q + + P + P Q S
Sbjct: 104 PNVFREKSMQNRYVQSGMMMSQYKLSQNSMHSSPASSNYQQTT-ISHSPSSRFVPPQTSS 162
Query: 319 VYSIVPQSWSPNPTPYF-ETPLAPFPNGSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKP 377
+PQ SP P+PY ++P P ++ P SY T+ P
Sbjct: 163 GNRFMPQQNSPVPSPYAPQSPAGYMP-------YSHPSSYTTH----------------P 199
Query: 378 QFRSSGGSEHSTEGSV-SLGDGQLNRYSSRNFPAERH--NPTVTGHQEQTYLQKETSTLQ 434
Q + + S G + ++ D +++ S N A H NP ++ ++ S+
Sbjct: 200 QMQQASVSSPIVAGGLRNIHDNKVSGPLSGN-SANHHADNPRHGSSEDYLHMVHRLSS-- 256
Query: 435 VEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLLASNFPPLPGSSSR- 493
+GD R R + P S K P L + + LP SS R
Sbjct: 257 --DDGDSSTMRNA--ASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQS---LPCSSPRD 309
Query: 494 MPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTECTSAQQLNMSTSSPCAAELT 553
+P +++L++ + K ++ + EQ+E + + +S+ S + +LT
Sbjct: 310 VPPDILLDSP---------ERKQKKQKKMKLGKDEKEQSEKAAMYDI-ISSPSKDSTKLT 359
Query: 554 ------ALSTTQQEKDLIEDSSVQKDGLNQTTIPVS---PPSTTKPSRASTASPCNNNIN 604
S Q++D+I S V+ +++ IP + P T+K T N +N
Sbjct: 360 LRLSRVRSSDMDQQEDMI--SGVENSNVSENDIPFNVQYPGQTSK--TPITPQDINRPLN 415
Query: 605 AATAVALQE 613
AA ++ QE
Sbjct: 416 AAQCLSQQE 424
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 37.4 bits (85), Expect = 0.049
Identities = 81/369 (21%), Positives = 148/369 (40%), Gaps = 69/369 (18%)
Query: 266 PIMVRIKAINTFFAKNG-----YRLMDSSIYSHPIQTQAQYASPVFMQPV--YNPHQQYS 318
P + R K++ + ++G Y+L +S++S P + Q + + P + P Q S
Sbjct: 104 PNVFREKSMQNRYVQSGMMMSQYKLSQNSMHSSPASSNYQQTT-ISHSPSSRFVPPQTSS 162
Query: 319 VYSIVPQSWSPNPTPYF-ETPLAPFPNGSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKP 377
+PQ SP P+PY ++P P ++ P SY T+ P
Sbjct: 163 GNRFMPQQNSPVPSPYAPQSPAGYMP-------YSHPSSYTTH----------------P 199
Query: 378 QFRSSGGSEHSTEGSV-SLGDGQLNRYSSRNFPAERH--NPTVTGHQEQTYLQKETSTLQ 434
Q + + S G + ++ D +++ S N A H NP ++ ++ S+
Sbjct: 200 QMQQASVSSPIVAGGLRNIHDNKVSGPLSGN-SANHHADNPRHGSSEDYLHMVHRLSS-- 256
Query: 435 VEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLLASNFPPLPGSSSR- 493
+GD R R + P S K P L + + LP SS R
Sbjct: 257 --DDGDSSTMRNA--ASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQS---LPCSSPRD 309
Query: 494 MPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTECTSAQQLNMSTSSPCAAELT 553
+P +++L++ + K ++ + EQ+E + + +S+ S + +LT
Sbjct: 310 VPPDILLDSP---------ERKQKKQKKMKLGKDEKEQSEKAAMYDI-ISSPSKDSTKLT 359
Query: 554 ------ALSTTQQEKDLIEDSSVQKDGLNQTTIPVS---PPSTTKPSRASTASPCNNNIN 604
S Q++D+I S V+ +++ IP + P T+K T N +N
Sbjct: 360 LRLSRVRSSDMDQQEDMI--SGVENSNVSENDIPFNVQYPGQTSK--TPITPQDINRPLN 415
Query: 605 AATAVALQE 613
AA ++ QE
Sbjct: 416 AAQCLSQQE 424
>gi|149944526 additional sex combs like 3 [Homo sapiens]
Length = 2248
Score = 36.6 bits (83), Expect = 0.084
Identities = 45/149 (30%), Positives = 63/149 (42%), Gaps = 12/149 (8%)
Query: 530 EQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDL---IEDSSVQKDGLNQTTIPVSPPS 586
E +E + L +++ + + L S T DL E SSV L T VS S
Sbjct: 688 EISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVS--S 745
Query: 587 TTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVV 646
PS S S N++IN +A Q+ + S +E P K+ SS +PL E N+
Sbjct: 746 LPLPSETSPIS--NSSINER--MAHQQRKSPSVSEEPLSPQKDESSATAKPLGE---NLT 798
Query: 647 SPTKNEDNGAPENSVEKPHEKPEARASKD 675
S KN N + PEA S+D
Sbjct: 799 SQQKNLSNTPEPIIMSSSSIAPEAFPSED 827
>gi|4758216 dishevelled 2 [Homo sapiens]
Length = 736
Score = 35.8 bits (81), Expect = 0.14
Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 9/95 (9%)
Query: 324 PQSWSPNPTPYFETPLAPFPNGS----FVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQF 379
P +SP P PY E + GS G S GS +++ A GRP ++ P+
Sbjct: 558 PHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEER---APES 614
Query: 380 RSSGGSEH--STEGSVSLGDGQLNRYSSRNFPAER 412
+S GSE S+ G G+ + S P R
Sbjct: 615 KSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSR 649
>gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo
sapiens]
Length = 1268
Score = 35.8 bits (81), Expect = 0.14
Identities = 66/324 (20%), Positives = 111/324 (34%), Gaps = 66/324 (20%)
Query: 343 PNGSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNR 402
P SFVN +NSP Y +++ + G P S+ + S+ GD
Sbjct: 151 PYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQM 210
Query: 403 YSSRNFPAER---------------------HNPTVTGHQEQT----------------- 424
++S+N P R P+ HQ+Q+
Sbjct: 211 FTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPST 270
Query: 425 ---YLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPST------AESKAPTP 475
++ T +L V N +L + S P ST S TP
Sbjct: 271 QDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTP 330
Query: 476 KFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGV-YKEKDNEELTISCPVPADEQTEC 534
+N P P +S P EL+ + KGV Y E N + + S P P ++
Sbjct: 331 P----TANHPVEPVTSVTQPSELLQQ-------KGVQYGEYVNNQAS-SAPTPLSSTSDD 378
Query: 535 TSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRAS 594
++ + ++ ++ S D +E S D L+ + +P +P AS
Sbjct: 379 EEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGS-YPDMLSSSASSPAPDPAPEPDPAS 437
Query: 595 TASPCNNNINAATAVALQEPRKLS 618
+P +A A + +P K++
Sbjct: 438 APAPA-----SAPAPVVPQPSKMA 456
Score = 32.0 bits (71), Expect = 2.1
Identities = 50/210 (23%), Positives = 73/210 (34%), Gaps = 27/210 (12%)
Query: 297 TQAQYASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGSFVNGFNSPGS 356
T + SP+ P HQQ S+ +WS P + L GS N+P
Sbjct: 232 TAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNP-- 289
Query: 357 YKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHNPT 416
T A ++ P +N P+ ST S S G + N P E P
Sbjct: 290 --TITVADSLSCPVMQNVQPPK----SSPVVSTVLSGSSGSSSTRTPPTANHPVE---PV 340
Query: 417 VTGHQEQTYLQKETSTLQVEQNGDYGRGR---------RTLFRGRRRREDDRISRPHPST 467
+ Q LQ++ Q G+Y + T ED+ ST
Sbjct: 341 TSVTQPSELLQQKG-----VQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSST 395
Query: 468 AESKAPTP-KFDLL-ASNFPPLPGSSSRMP 495
S +P P +D L ++P + SS+ P
Sbjct: 396 TSSASPMPNSYDALEGGSYPDMLSSSASSP 425
>gi|87162461 fragile X mental retardation 2 [Homo sapiens]
Length = 1311
Score = 35.4 bits (80), Expect = 0.19
Identities = 47/202 (23%), Positives = 72/202 (35%), Gaps = 11/202 (5%)
Query: 465 PSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMS--DVVKGVYKEKDNEELTI 522
PS A SK PKF +L ++ LP S + E++ E S + ++ +E+ T
Sbjct: 328 PSAASSKTKLPKFTILQTSEVSLPSDPSCVE-EILREMTHSWPTPLTSMHTAGHSEQSTF 386
Query: 523 SCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPV 582
S +P E T L A ++S +D ++ SS + D T+
Sbjct: 387 S--IPGQESQHLTPGFTLQKWNDPTTRASTKSVSFKSMLEDDLKLSSDEDDLEPVKTLTT 444
Query: 583 SPPSTTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELR 642
+T A P NN +N A P + E SS
Sbjct: 445 QCTATELYQAVEKAKPRNNPVNPPLATPQPPPAVQASGGSGSSSESESSS------ESDS 498
Query: 643 SNVVSPTKNEDNGAPENSVEKP 664
S T +E N AP + +P
Sbjct: 499 DTESSTTDSESNEAPRVATPEP 520
>gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo
sapiens]
Length = 1233
Score = 35.4 bits (80), Expect = 0.19
Identities = 57/285 (20%), Positives = 95/285 (33%), Gaps = 23/285 (8%)
Query: 343 PNGSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNR 402
P SFVN +NSP Y +++ + G P S+ + S+ GD
Sbjct: 151 PYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQM 210
Query: 403 YSSRNFPAER------HNPTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRRE 456
++S+N P R + T + L S +Q G T
Sbjct: 211 FTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPST 270
Query: 457 DDRISRPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKD 516
D + R H + P + S P+ + V + S VV V
Sbjct: 271 QDNLIRNHTGSLAVANNNPTITVADSLSCPVM--------QNVQPPKSSPVVSTVLSGSS 322
Query: 517 NEELTISCPV---PADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKD 573
T + P P + T T +L ++ ++ S D +E S D
Sbjct: 323 GSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVDSSSTTSSASPMPNSYDALEGGS-YPD 381
Query: 574 GLNQTTIPVSPPSTTKPSRASTASPCNNNINAATAVALQEPRKLS 618
L+ + +P +P AS +P +A A + +P K++
Sbjct: 382 MLSSSASSPAPDPAPEPDPASAPAPA-----SAPAPVVPQPSKMA 421
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,912,045
Number of Sequences: 37866
Number of extensions: 1579712
Number of successful extensions: 4644
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 4445
Number of HSP's gapped (non-prelim): 294
length of query: 724
length of database: 18,247,518
effective HSP length: 110
effective length of query: 614
effective length of database: 14,082,258
effective search space: 8646506412
effective search space used: 8646506412
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.