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Search of human proteins with 40255180
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40255180 coiled-coil domain containing 83 [Homo sapiens]
(444 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40255180 coiled-coil domain containing 83 [Homo sapiens] 892 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 60 3e-09
gi|166295204 hypothetical protein LOC80127 [Homo sapiens] 55 1e-07
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 54 2e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 49 7e-06
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 49 7e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 49 9e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 49 1e-05
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 49 1e-05
gi|45505178 cancer antigen 1 [Homo sapiens] 48 2e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 47 3e-05
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 47 3e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 47 3e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 47 3e-05
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 47 5e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 46 8e-05
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 46 8e-05
gi|100814339 coiled-coil domain containing 146 [Homo sapiens] 46 8e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 1e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 45 1e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 45 1e-04
gi|4758646 kinesin family member 3B [Homo sapiens] 45 2e-04
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 44 2e-04
gi|81295809 pericentrin [Homo sapiens] 44 3e-04
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 44 4e-04
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 44 4e-04
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 44 4e-04
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 43 5e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 43 5e-04
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 43 7e-04
>gi|40255180 coiled-coil domain containing 83 [Homo sapiens]
Length = 444
Score = 892 bits (2306), Expect = 0.0
Identities = 444/444 (100%), Positives = 444/444 (100%)
Query: 1 MENSGKANKKDTHDGPPKEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHER 60
MENSGKANKKDTHDGPPKEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHER
Sbjct: 1 MENSGKANKKDTHDGPPKEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHER 60
Query: 61 NSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQI 120
NSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQI
Sbjct: 61 NSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQI 120
Query: 121 SNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDT 180
SNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDT
Sbjct: 121 SNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDT 180
Query: 181 RKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIH 240
RKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIH
Sbjct: 181 RKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIH 240
Query: 241 ELEAENLVLIDQLSNCRLVDLKIPRYPVLHSCPTSNPRHLLLLPLESCLISARRCWRLYL 300
ELEAENLVLIDQLSNCRLVDLKIPRYPVLHSCPTSNPRHLLLLPLESCLISARRCWRLYL
Sbjct: 241 ELEAENLVLIDQLSNCRLVDLKIPRYPVLHSCPTSNPRHLLLLPLESCLISARRCWRLYL 300
Query: 301 TQAAGLEVPPEEMSLELPETHIEEKSELQPTEVESRDLMSSSDESTILHLSHENSIEDLQ 360
TQAAGLEVPPEEMSLELPETHIEEKSELQPTEVESRDLMSSSDESTILHLSHENSIEDLQ
Sbjct: 301 TQAAGLEVPPEEMSLELPETHIEEKSELQPTEVESRDLMSSSDESTILHLSHENSIEDLQ 360
Query: 361 YVKIDKEENSGTEFGDTDMKYLLYEDEKDFKDYVNLGPLGVKLMSVESKKMPIHFQEKEI 420
YVKIDKEENSGTEFGDTDMKYLLYEDEKDFKDYVNLGPLGVKLMSVESKKMPIHFQEKEI
Sbjct: 361 YVKIDKEENSGTEFGDTDMKYLLYEDEKDFKDYVNLGPLGVKLMSVESKKMPIHFQEKEI 420
Query: 421 PVKLYKDVRSPESHITYKMMKSFL 444
PVKLYKDVRSPESHITYKMMKSFL
Sbjct: 421 PVKLYKDVRSPESHITYKMMKSFL 444
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 60.5 bits (145), Expect = 3e-09
Identities = 109/434 (25%), Positives = 193/434 (44%), Gaps = 73/434 (16%)
Query: 38 DAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSE-EKAEGLPVVTREDVE 96
+A E+ + Q++TLR++N+ E S L E+ I K L E EK + L + D++
Sbjct: 1490 NAYEEVVDQLETLRRENKNLQEEISDLTEQ----IAETGKNLQEAEKTKKLVEQEKSDLQ 1545
Query: 97 EAMKE-KWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSL 155
A++E + E ++ K LR +++++S + K+ EK+ E S+R A+ + S+
Sbjct: 1546 VALEEVEGSLEHEESKILR-VQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSV 1604
Query: 156 -------QNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLID 208
+ND +K+ E +I L + +++ + QK Q +K D
Sbjct: 1605 LDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAE------TQKHLRTVQGQLK--D 1656
Query: 209 KGSYLE--IWENDWLKKEVAIHRK-------EVEELKNAIHELEAENLVLIDQLSNCRLV 259
+L+ + N+ LK+++AI + E+EE+K A+ + E +LS L+
Sbjct: 1657 SQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTR-----RLSEQELL 1711
Query: 260 DLKIPRYPVLHSCPTS--NPRHLLLLPLESCLI----------SARRCWRLYLTQAAGLE 307
D R +LHS TS N + L + C +A + +T AA
Sbjct: 1712 DAS-DRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAA--- 1767
Query: 308 VPPEEMSLEL-PETHIEE-KSELQPTEVESRDLMSSSDESTILHLSH--------ENSIE 357
+ EE+ E H+E K L+ T +DL DE+ L L EN +
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRLDEAEQLALKGGKKQIQKLENRVR 1824
Query: 358 DLQYVKIDKEENSGTEF------GDTDMKYLLYEDEKDFKDYVNLGPLGVKLMS-VESKK 410
+L+ ++D E+ G E + +K + Y+ E+D K+ + L L KL + V+S K
Sbjct: 1825 ELEN-ELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYK 1883
Query: 411 MPIHFQEKEIPVKL 424
E++ +L
Sbjct: 1884 RQAEEAEEQANTQL 1897
>gi|166295204 hypothetical protein LOC80127 [Homo sapiens]
Length = 529
Score = 55.1 bits (131), Expect = 1e-07
Identities = 63/273 (23%), Positives = 120/273 (43%), Gaps = 31/273 (11%)
Query: 1 MENSGKANKKDTHDGPPKEIKLPTSEALLD--------YQCQIKEDAVEQFMFQ--IKTL 50
M + GK KK G + + T E+++D ++ +++ + + ++ + L
Sbjct: 1 MPSKGKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRIL 60
Query: 51 RKKNQKYHERNSRLKEEQIWHIRHLLKELSEEK---AEGLPVVTREDVEEAMKEKWKFER 107
K N+ ++ ++ E+ I + LK+ +EK E L E E+A +EK K E+
Sbjct: 61 AKSNEDLKKKQCKM-EKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQ 119
Query: 108 DQEKNLRDMRMQISNAEKLFLEKLSE-KEYWEEYKNVGSERHAKLITSLQNDINTVKENA 166
+ QI+ E F +K E E K V + K+ ++ +++ +KEN
Sbjct: 120 KYTR-------QINELEGQFHQKAKEIGMIHTELKAVRQFQKRKI--QVERELDDLKENL 170
Query: 167 EKMSEHYKITLEDTRKKIIKET--LLQLDQKK-----EWATQNAVKLIDKGSYLEIWEND 219
++ TL + +E L Q +KK E A A+ ++ END
Sbjct: 171 RNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKEND 230
Query: 220 WLKKEVAIHRKEVEELKNAIHELEAENLVLIDQ 252
+L+K +A H KE + L+ +L+ + +L+ Q
Sbjct: 231 YLQKALAYHLKETDALQKNSQKLQESHTLLLHQ 263
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 54.3 bits (129), Expect = 2e-07
Identities = 51/204 (25%), Positives = 97/204 (47%), Gaps = 17/204 (8%)
Query: 49 TLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERD 108
TL KNQ+ N++ +EE++ L+E + L V E ++ + K K ++
Sbjct: 538 TLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKS 597
Query: 109 QEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKL----ITSLQNDINTVKE 164
+E N ++R Q+ N K ++E+L ++ + K + + + L+ ++ + K+
Sbjct: 598 EE-NCNNLRKQVENKNK-YIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQ 655
Query: 165 NAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKL---IDKGSYLEIWENDWL 221
++++ Y+ +ED KKI +E LL+ +K + AVKL IDK +I E
Sbjct: 656 KFGEITDTYQKEIED--KKISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAE---- 709
Query: 222 KKEVAIHRKEVEELKNAIHELEAE 245
VA+ K + I E ++E
Sbjct: 710 --MVALMEKHKHQYDKIIEERDSE 731
Score = 37.7 bits (86), Expect = 0.021
Identities = 64/270 (23%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 1 MENSGKANKKDTHDGPPKEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHER 60
ME S KA + E + + E LL + Q E +Q L+KK+ + E
Sbjct: 363 MEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEM 422
Query: 61 NSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMK----EKWKFERDQEKNLRDM 116
+++ + L K L E++ E + E +K E + +EK + D+
Sbjct: 423 TKLTNNKEV-ELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDL 481
Query: 117 RMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLI--TSLQNDINTVK-ENAEKMSEHY 173
+Q++ SE+ Y +E K++ +E + + T L + N + EN E E
Sbjct: 482 EIQLTAITT------SEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETS 535
Query: 174 KITLE--------DTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWEN------D 219
+TLE + KK + L Q++ +E TQ +L L+ + D
Sbjct: 536 DMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLD 595
Query: 220 WLKKEVAIHRKEVEELKNAIHELEAENLVL 249
++ RK+VE I EL+ EN L
Sbjct: 596 KSEENCNNLRKQVENKNKYIEELQQENKAL 625
Score = 36.6 bits (83), Expect = 0.047
Identities = 41/144 (28%), Positives = 71/144 (49%), Gaps = 12/144 (8%)
Query: 29 LDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRL-----KEEQIWHIRHLLK-ELSEE 82
+D +CQ K E K + ++ ER+S L KE++ +R L+ ELS
Sbjct: 699 IDKRCQHK--IAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNL 756
Query: 83 KAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWE-EYK 141
KAE L V + ++E KEK K R+ ++N ++ + + FL + E YW+ + K
Sbjct: 757 KAELLSVKKQLEIEREEKEKLK--REAKENTATLKEKKDKKTQTFLLETPE-IYWKLDSK 813
Query: 142 NVGSERHAKLITSLQNDINTVKEN 165
V S+ ++ TS+ + I+ K +
Sbjct: 814 AVPSQTVSRNFTSVDHGISKDKRD 837
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 49.3 bits (116), Expect = 7e-06
Identities = 42/169 (24%), Positives = 81/169 (47%), Gaps = 17/169 (10%)
Query: 81 EEKAEGLPVVTREDVEEAMKEKWKFER---DQEKNLRDMRMQISNAEKLFLEKLSEKEYW 137
E+K + L V +E+ KE+ + ++ ++E + MR ++ +KLS KE
Sbjct: 878 EQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKE-- 935
Query: 138 EEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKE---TLLQLDQ 194
+ ++ +E + + + + VK+ A++M E K L D K+ KE T L+L Q
Sbjct: 936 -DSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ 994
Query: 195 KK--------EWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEEL 235
K+ E A N+ + D S LE + + ++ +HR+E+ ++
Sbjct: 995 KEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDV 1043
Score = 37.4 bits (85), Expect = 0.028
Identities = 54/259 (20%), Positives = 112/259 (43%), Gaps = 46/259 (17%)
Query: 34 QIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIW--------HIRHLLK-ELSEEKA 84
++K++ V+ + K QK HE+ KE+++ + +K L + ++
Sbjct: 461 RVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQS 520
Query: 85 EGLPVVTREDVEEAMK------EKWKFERDQEKNLRDMRMQI-----------SNAEKLF 127
E L + ++ +E++ +K + E LRD++ + S+ EK
Sbjct: 521 EYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSL 580
Query: 128 LEKLSEKEYWEEYKNVGSERHAKLITSL----QNDINTVK--------ENAEKMSEHYKI 175
E ++ + + +H K IT + + ++ ++K E + + + Y+
Sbjct: 581 QENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQT 640
Query: 176 TLEDTRKKI--IKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVE 233
+E R+K KETLL + KE Q ++ +++ + ++ D + E+ E+
Sbjct: 641 EMEKLREKCEQEKETLL---KDKEIIFQAHIEEMNEKTLEKL---DVKQTELESLSSELS 694
Query: 234 ELKNAIHELEAENLVLIDQ 252
E+ A H+LE E VL DQ
Sbjct: 695 EVLKARHKLEEELSVLKDQ 713
Score = 35.4 bits (80), Expect = 0.10
Identities = 60/308 (19%), Positives = 138/308 (44%), Gaps = 39/308 (12%)
Query: 85 EGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQ---ISNAEKLFLEKLSEK-EYWEEY 140
+G V T E +++ +K + + ++ ++ + Q +++ ++ E+L E+ + E+
Sbjct: 274 DGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKI 333
Query: 141 KNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIK------ETLLQLDQ 194
K++ KLIT L++ N + E++ + + + +T++++ + E + QL
Sbjct: 334 KDLHMAEKTKLITQLRDAKNLI----EQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRS 389
Query: 195 KKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVE-----------ELKNAIHELE 243
+ + T +L ++ E + L+K ++ +K E ++K E
Sbjct: 390 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSE 449
Query: 244 AENLVLIDQLSNCR--LVDL-------KIPRYPVLHSCPTSNPRHLLLLPLESCLISARR 294
E + L +LS + +VD+ +I + LH + L L++ +
Sbjct: 450 EERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQE 509
Query: 295 CWRLYL--TQAAGLEVPPE---EMSLELPETHIEEKSELQPTEVESRDLMSSSDESTILH 349
++ L +Q+ L++ E + SL L E +++K+ L +E + RDL ++
Sbjct: 510 QMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRI 569
Query: 350 LSHENSIE 357
L E+S+E
Sbjct: 570 LELESSLE 577
Score = 35.4 bits (80), Expect = 0.10
Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 11/192 (5%)
Query: 64 LKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQIS-N 122
LKE+++ I L K+L++ + ++ + E A+ K +++ L D +S
Sbjct: 1362 LKEKKV-EISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFK 1420
Query: 123 AEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLE-DTR 181
+ L EK+S E +++ N SE K + NTVKE ++ K E D +
Sbjct: 1421 VDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQ 1480
Query: 182 KKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIH- 240
++KE +LDQ+ + ++ D S +E E++ L+ E+ + EL++ I
Sbjct: 1481 INLLKE---ELDQQNKRFDCLKGEMEDDKSKMEKKESN-LETELKSQTARIMELEDHITQ 1536
Query: 241 ---ELEAENLVL 249
E+E+ N VL
Sbjct: 1537 KTIEIESLNEVL 1548
Score = 33.1 bits (74), Expect = 0.52
Identities = 58/239 (24%), Positives = 98/239 (41%), Gaps = 48/239 (20%)
Query: 34 QIKEDAVEQFMFQIKTLRKKN-------QKYHERNSRLKEEQIWHIRHLLKELSEEKAEG 86
Q K++ F KTL++K QK E +S L ++ H R ++EL+ K E
Sbjct: 1826 QAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVH-RVEMEELTS-KYEK 1883
Query: 87 LPVVTRED--------VEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWE 138
L + + D +EE +EK K Q K L +M Q ++ E
Sbjct: 1884 LQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLE-------------- 1929
Query: 139 EYKNVGSERH----AKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQ 194
+K G+ER K I LQ D+ +++ ++ E K + R++ IK+ L+
Sbjct: 1930 -FKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLEL 1988
Query: 195 K-----KEWATQNAVKLIDKGSYLEIWENDWLKKEVAI-------HRKEVEELKNAIHE 241
K K+ + +L K LE+ + + K + H++E +L I E
Sbjct: 1989 KHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAE 2047
Score = 32.3 bits (72), Expect = 0.89
Identities = 52/247 (21%), Positives = 104/247 (42%), Gaps = 39/247 (15%)
Query: 38 DAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIR--HLLKELSEEKAEGLPVVTREDV 95
D V+ F++ TL K E+ S L++ W + K+ + V +
Sbjct: 1412 DQVQDLSFKVDTLSK------EKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQI 1465
Query: 96 EEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSL 155
+ +K K +E+D++ NL ++ ++ K F E E + K+ ++ + L T L
Sbjct: 1466 QLELKSKEAYEKDEQINL--LKEELDQQNKRFDCLKGEME---DDKSKMEKKESNLETEL 1520
Query: 156 QNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLI-------- 207
++ + E + +H IT + + + E L +Q+K+ + V+ +
Sbjct: 1521 KSQTARIME----LEDH--ITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE 1574
Query: 208 DKGSYLEIWENDWL---------KKEVAIHRKEVEELKNAIHELEAENLVLIDQL---SN 255
+K + ++ E L K E+ +KE+E + ++ E E L D+L S
Sbjct: 1575 EKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA 1634
Query: 256 CRLVDLK 262
+L +LK
Sbjct: 1635 AKLAELK 1641
Score = 30.0 bits (66), Expect = 4.4
Identities = 33/143 (23%), Positives = 63/143 (44%), Gaps = 17/143 (11%)
Query: 49 TLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTR-EDVEEAMKEKWKFER 107
T+++ K E + L E LLK+++E+ + R E++ +A +E
Sbjct: 2015 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREE------ 2068
Query: 108 DQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHA--KLITSLQNDINTVKEN 165
+ +RD++ Q+ +K + +KL ++E N G++ +L T L + ++
Sbjct: 2069 EMTAKVRDLQTQLEELQKKYQQKLEQEE------NPGNDNVTIMELQTQLAQKTTLISDS 2122
Query: 166 AEKMSEHYK--ITLEDTRKKIIK 186
K E + LED KK K
Sbjct: 2123 KLKEQEFREQIHNLEDRLKKYEK 2145
Score = 29.3 bits (64), Expect = 7.5
Identities = 48/220 (21%), Positives = 93/220 (42%), Gaps = 27/220 (12%)
Query: 52 KKNQKYH--ERNSRL--KEEQIWHIRHLLKELSEEKAEGLPV------VTREDVEEAMKE 101
KK + H E N++L +E ++ + LK + ++E L V V +E
Sbjct: 1667 KKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADS 1726
Query: 102 KWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWE----EYKNVGSERHAKLITSL-- 155
+ ++ E+ + ++ ++ EKL EKE E + ER KL +
Sbjct: 1727 QGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAK 1786
Query: 156 ----QNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLI-DKG 210
Q+ I ++E E+ ++ Y + + +K + +Q Q E + K + +K
Sbjct: 1787 QHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKE 1846
Query: 211 SYLEIWE------NDWLKKEVAIHRKEVEELKNAIHELEA 244
+I E + L ++ +HR E+EEL + +L+A
Sbjct: 1847 LTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQA 1886
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 49.3 bits (116), Expect = 7e-06
Identities = 104/452 (23%), Positives = 186/452 (41%), Gaps = 96/452 (21%)
Query: 26 EALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAE 85
E L CQ+K+ E + + + LR + K+ S H++H+ E+KA
Sbjct: 507 EELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKS--------HLKHIY----EKKAH 554
Query: 86 GLPVVTREDVEEAMKEKWKFE---RDQEKNLRDM----RMQISNAE------KLFLEKLS 132
L + E+ K+ KFE +++E+ L + R+Q A+ K +E S
Sbjct: 555 DLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNS 614
Query: 133 EKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKI---IKETL 189
EK Y E + + ++ D+ K EK S+ + LED R++ I E
Sbjct: 615 EKVYAEMKEQ---------MEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVELK 665
Query: 190 LQLDQKKEWATQ--NAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIH--ELEAE 245
L+ +Q+K Q NA E D L ++ H +E+E L+ + +E E
Sbjct: 666 LEHEQEKTHLLQQHNA-------------EKDSLVRD---HEREIENLEKQLRAANMEHE 709
Query: 246 NLVLIDQLSNCRLV-DLKIPRYPVLHSCPTSNPRHLLLLPLESCLI---SARRCWRLYLT 301
N + + + +++ D++ + + N + L +E L+ +R R +
Sbjct: 710 NQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQL-VELGLLREEEKQRATREHEI 768
Query: 302 QAAGLEVPPEEMSLELPETHIEE--------KSELQPTEVESRDLMSSSD------ESTI 347
L+ E+M +EL +TH E S+L+ E E ++ S ++TI
Sbjct: 769 VVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQTTI 828
Query: 348 LHLSHENSIEDLQYVKIDKEENSGTEFGDTDMKYLLYEDEKDFKDYVNLGPLGVKLM--S 405
L ENS + L + D K +EDEK K + +K++
Sbjct: 829 SSLKEENSQQQLA---------AERRLQDVRQK---FEDEK--KQLIRDNDQAIKVLQDE 874
Query: 406 VESKKMPIHFQEKEIPVKLYKDVRSPESHITY 437
+E++ + EK++ +K++ S E ITY
Sbjct: 875 LENRSNQVRCAEKKLQ---HKELESQE-QITY 902
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 48.9 bits (115), Expect = 9e-06
Identities = 48/230 (20%), Positives = 107/230 (46%), Gaps = 24/230 (10%)
Query: 26 EALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAE 85
E L + + +++E E+ Q K LR++ ++ E+ L+E++ + + EEK
Sbjct: 300 ERLREQEGKMREQE-EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358
Query: 86 GLPVVTREDVEEAMKEK---WKFE---RDQEKNLRDMRMQISNAEKLFLEK----LSEKE 135
RE E+ +++ W+ E R+QE+ +RD ++ ++ EK +++
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 418
Query: 136 YWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQK 195
WE+ + + E+ +Q ++ EKM E +I + + + +ET+ + ++K
Sbjct: 419 MWEQVEKMREEK------KMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK 472
Query: 196 KEWATQNAVKLIDKGSYLEIWENDWL--KKEVAIHRKEVEELKNAIHELE 243
+ +N + +K W+ L +KE +++++E + I E E
Sbjct: 473 MQKQEENMWEQEEKE-----WQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517
Score = 47.8 bits (112), Expect = 2e-05
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 14/191 (7%)
Query: 52 KKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEK 111
+K + + + + +EE+IW +++ E + + +E + E + W +QE+
Sbjct: 496 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW----EQEE 551
Query: 112 NLRDMRMQISNAEKLFLEKLSEKEY--WE-EYKNVGSERHAKLITSLQNDINTVKENAEK 168
+RD ++ + E+ +K E+E W+ E K ER + ++ + ++E EK
Sbjct: 552 KMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 611
Query: 169 MSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWL---KKEV 225
M E + E K +E +Q ++K W + + ++ ++WE L K+++
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE----KMWEQQRLPEQKEKL 667
Query: 226 AIHRKEVEELK 236
H K E+ K
Sbjct: 668 WEHEKMQEQEK 678
Score = 45.8 bits (107), Expect = 8e-05
Identities = 47/243 (19%), Positives = 109/243 (44%), Gaps = 28/243 (11%)
Query: 1 MENSGKANKKDTHDGPPK---EIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKY 57
ME + +K T D K E ++ E + + ++ + E+ Q + ++++ +K
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626
Query: 58 HERNSRLKE--EQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRD 115
E+ +++E E++W + E E+ E ++ + E ++ W+ E+ QE+
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWE------QQRLPEQKEKLWEHEKMQEQE--- 677
Query: 116 MRMQISNAEKLFLEKL-------SEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEK 168
+MQ EK++ ++ EK+ W++ K E + ++ + ++E EK
Sbjct: 678 -KMQ-EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEK 735
Query: 169 MSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIH 228
M E + E + +E + ++K W Q + +K +WE++ ++++ I
Sbjct: 736 MQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK-----LWEHEKMQEQEKIW 790
Query: 229 RKE 231
+E
Sbjct: 791 EQE 793
Score = 40.4 bits (93), Expect = 0.003
Identities = 36/167 (21%), Positives = 84/167 (50%), Gaps = 12/167 (7%)
Query: 34 QIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTRE 93
Q++ + +++ M++ +++ + E+ R +EE++W L+E + E + R+
Sbjct: 264 QVQTNTLQEEMWR----QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQ 319
Query: 94 DVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNV--GSERHAKL 151
E+ ++E+ K R+QEK LR+ + ++ E+ E+ E++ WE+ + + E+ +
Sbjct: 320 --EKRLREQEKELREQEKELREQK-ELREQEEQMQEQ--EEKMWEQEEKMREQEEKMWRQ 374
Query: 152 ITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEW 198
L ++E +KM + + E + KE ++ +Q+K W
Sbjct: 375 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR-EQEKMW 420
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 48.5 bits (114), Expect = 1e-05
Identities = 45/208 (21%), Positives = 92/208 (44%), Gaps = 35/208 (16%)
Query: 46 QIKTLRKKNQKYHERNSRLKEEQ--IWHIRHLLKELSEEKAEGLPVVTRED--------- 94
Q + + ++ +K HE+ +++E++ +W ++E E+ E + R++
Sbjct: 323 QEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEK 382
Query: 95 VEEAMKEKWK--------FERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSE 146
++E +E W+ E+ QEK R + EK+ + E+E W + E
Sbjct: 383 IQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKI---REQEEEMWRQ-----EE 434
Query: 147 RHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKL 206
+ +L +Q+ ++E EKM E + E K +E +Q ++K W + +K
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Query: 207 IDKGSYLEIWEND---WLKKEVAIHRKE 231
+K IWE + W ++E ++E
Sbjct: 495 EEK-----IWEQEEKMWRQEEKMWEQEE 517
Score = 33.9 bits (76), Expect = 0.31
Identities = 44/229 (19%), Positives = 93/229 (40%), Gaps = 35/229 (15%)
Query: 41 EQFMFQIKTLRKKNQKYHER-NSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAM 99
+Q + L K+ Q + ++++E ++W+ LL + EEK +E E+
Sbjct: 258 QQLQVEADRLGKELQSVSAKLQAQVEENELWN---LLNQQQEEKMWRQEEKIQEQEEKMC 314
Query: 100 KEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDI 159
+++ K +EK R EK+ + E + W + + + +
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKI---REQEDKMWRQEEKIREQE------------ 359
Query: 160 NTVKENAEKM-SEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWEN 218
++E EKM + KI +D + +Q +++ W + ++ ++ ++W
Sbjct: 360 EKIREQEEKMWRQEEKIREQDEK--------IQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 219 DWLKKEVAIHRKEVEE----LKNAIHELEAENLVLIDQLSNCRLVDLKI 263
+ +E +E EE + I ELE ++ DQ R V+ K+
Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEE---MMQDQEEKLREVEEKM 457
Score = 32.0 bits (71), Expect = 1.2
Identities = 35/168 (20%), Positives = 78/168 (46%), Gaps = 14/168 (8%)
Query: 18 KEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLK--------EEQI 69
+E KL E + + + ++ E+ Q + ++++ +K + LK EE++
Sbjct: 446 QEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
Query: 70 WHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLE 129
W + E E+ E + R+ EE M+E+ QE+ +++ +++ E+ L
Sbjct: 506 WRQEEKMWEQEEKMQEQEEKMQRQ--EEKMREQEVRLWQQEEKMQEQEVRLQELEER-LG 562
Query: 130 KLSEKE--YWEEYKNVGSERHAKLITSLQNDINTVK-ENAEKMSEHYK 174
KL +K + GS+R L LQ ++ + + ++ ++ +HY+
Sbjct: 563 KLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 48.5 bits (114), Expect = 1e-05
Identities = 45/208 (21%), Positives = 92/208 (44%), Gaps = 35/208 (16%)
Query: 46 QIKTLRKKNQKYHERNSRLKEEQ--IWHIRHLLKELSEEKAEGLPVVTRED--------- 94
Q + + ++ +K HE+ +++E++ +W ++E E+ E + R++
Sbjct: 323 QEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEK 382
Query: 95 VEEAMKEKWK--------FERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSE 146
++E +E W+ E+ QEK R + EK+ + E+E W + E
Sbjct: 383 IQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKI---REQEEEMWRQ-----EE 434
Query: 147 RHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKL 206
+ +L +Q+ ++E EKM E + E K +E +Q ++K W + +K
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Query: 207 IDKGSYLEIWEND---WLKKEVAIHRKE 231
+K IWE + W ++E ++E
Sbjct: 495 EEK-----IWEQEEKMWRQEEKMWEQEE 517
Score = 33.9 bits (76), Expect = 0.31
Identities = 44/229 (19%), Positives = 93/229 (40%), Gaps = 35/229 (15%)
Query: 41 EQFMFQIKTLRKKNQKYHER-NSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAM 99
+Q + L K+ Q + ++++E ++W+ LL + EEK +E E+
Sbjct: 258 QQLQVEADRLGKELQSVSAKLQAQVEENELWN---LLNQQQEEKMWRQEEKIQEQEEKMC 314
Query: 100 KEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDI 159
+++ K +EK R EK+ + E + W + + + +
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKI---REQEDKMWRQEEKIREQE------------ 359
Query: 160 NTVKENAEKM-SEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWEN 218
++E EKM + KI +D + +Q +++ W + ++ ++ ++W
Sbjct: 360 EKIREQEEKMWRQEEKIREQDEK--------IQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 219 DWLKKEVAIHRKEVEE----LKNAIHELEAENLVLIDQLSNCRLVDLKI 263
+ +E +E EE + I ELE ++ DQ R V+ K+
Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEE---MMQDQEEKLREVEEKM 457
Score = 32.0 bits (71), Expect = 1.2
Identities = 35/168 (20%), Positives = 78/168 (46%), Gaps = 14/168 (8%)
Query: 18 KEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLK--------EEQI 69
+E KL E + + + ++ E+ Q + ++++ +K + LK EE++
Sbjct: 446 QEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
Query: 70 WHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLE 129
W + E E+ E + R+ EE M+E+ QE+ +++ +++ E+ L
Sbjct: 506 WRQEEKMWEQEEKMQEQEEKMQRQ--EEKMREQEVRLWQQEEKMQEQEVRLQELEER-LG 562
Query: 130 KLSEKE--YWEEYKNVGSERHAKLITSLQNDINTVK-ENAEKMSEHYK 174
KL +K + GS+R L LQ ++ + + ++ ++ +HY+
Sbjct: 563 KLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
>gi|45505178 cancer antigen 1 [Homo sapiens]
Length = 641
Score = 47.8 bits (112), Expect = 2e-05
Identities = 41/174 (23%), Positives = 87/174 (50%), Gaps = 7/174 (4%)
Query: 41 EQFMFQIKTLRKKNQKYHERNSRL--KEEQIWHIRHLLKELSEEKAEGLPVVTRE---DV 95
E++M +++ K +Y E + L KEE++ ++ L KEL + A L ++ RE
Sbjct: 286 ERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQE 345
Query: 96 EEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSL 155
+E + + +F++ +++NL + + S EKL L ++ ++ E + + + + I +
Sbjct: 346 QEFLSLQEEFQKLEKENLEERQKLKSRLEKL-LTQVRNLQFMSENERTKNIKLQQQINEV 404
Query: 156 QNDINTVKENAEKMSE-HYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLID 208
+N+ +K+ + E +Y E + K E +L+ D K+ T ++ L D
Sbjct: 405 KNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPD 458
Score = 46.6 bits (109), Expect = 5e-05
Identities = 44/210 (20%), Positives = 104/210 (49%), Gaps = 28/210 (13%)
Query: 47 IKTLRKKNQKYHERNSRLKEEQIW---HIRHLLKELSEEKAEGLPVVTR--EDVEEAMKE 101
++ L+ N+K R L+ ++ ++ L ++++++ + V+ + E+VEE +++
Sbjct: 173 LQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVF-IDVINKLKENVEELIED 231
Query: 102 KWKF---ERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWE-EYKNVGSERHAKLITSLQN 157
K+K + D +K L+++ ++N +K E ++KE + ++K + A + +
Sbjct: 232 KYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKI----KANYVCLQER 287
Query: 158 DINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWE 217
+ +++ + +S++ ++ ++K+ E L QL ++ E AT +A+
Sbjct: 288 YMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASAL------------- 334
Query: 218 NDWLKKEVAIHRKEVEELKNAIHELEAENL 247
D LK+E +E L+ +LE ENL
Sbjct: 335 -DLLKREKEAQEQEFLSLQEEFQKLEKENL 363
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 47.4 bits (111), Expect = 3e-05
Identities = 51/248 (20%), Positives = 111/248 (44%), Gaps = 33/248 (13%)
Query: 26 EALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSE---- 81
E + + + +I+E E+ M++ + + +K E R ++E++W ++E E
Sbjct: 423 EKIREQEEKIREQ--EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 480
Query: 82 -EKAEGLPVVTRE------------DVEEAMKEK----WKFE---RDQEKNLRDMRMQIS 121
EK + ++ D EE ++E+ W+ E R+QE+ +R+ +I
Sbjct: 481 KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Query: 122 NAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTR 181
E++ E+ EK +E K E+ + ++ ++E EK+ E + E
Sbjct: 541 EQEEMMQEQ-EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
Query: 182 KKIIKETLLQLDQKKEWATQNAV-----KLIDKGSYLEIWENDWLKKEVAIHRKEVEELK 236
K +E ++Q ++K W + + K+ ++ + E ++EV + ++E E+++
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE-EKMQ 658
Query: 237 NAIHELEA 244
LEA
Sbjct: 659 EHQEHLEA 666
Score = 42.0 bits (97), Expect = 0.001
Identities = 47/224 (20%), Positives = 93/224 (41%), Gaps = 28/224 (12%)
Query: 18 KEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERN------SRLKEEQIWH 71
KE+K A L Q + + +++++ K Q E N ++ +EE++W
Sbjct: 245 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 304
Query: 72 IRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKL 131
++E E+ +E E+ +++ K +EK R M EK+ +
Sbjct: 305 QEEKIQEWEEK--------IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM---RR 353
Query: 132 SEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRK----KIIKE 187
E+ WE+ E+ +L + ++E EKM E KI ++ ++ KI ++
Sbjct: 354 QEEMMWEK-----EEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 188 TLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKE 231
Q + K W + K+ ++ + E ++E IH +E
Sbjct: 409 EKRQEQEAKMWRQEE--KIREQEEKIREQEKKMWRQEEKIHEQE 450
Score = 39.3 bits (90), Expect = 0.007
Identities = 36/198 (18%), Positives = 90/198 (45%), Gaps = 9/198 (4%)
Query: 50 LRKKNQKYHERNSRLK--EEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFER 107
+R++ + E+ +++ EE +W ++EL E+ E + +E+ + ++ + E+
Sbjct: 351 MRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 410
Query: 108 DQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAE 167
QE+ + R + E+ + EK+ W + + + + + Q ++ E
Sbjct: 411 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE-E 469
Query: 168 KMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAI 227
K+ E +I + ++K+ ++ ++ ++K W + K+ D+ + E ++E I
Sbjct: 470 KIREQEEIWRQ--KEKMHEQEKIRKQEEKVWRQEE--KMHDQEEKIREQEEKMWRQEEKI 525
Query: 228 HRKE--VEELKNAIHELE 243
+E + E + I E E
Sbjct: 526 REQEEKIREQEEKIREQE 543
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 47.4 bits (111), Expect = 3e-05
Identities = 61/253 (24%), Positives = 118/253 (46%), Gaps = 28/253 (11%)
Query: 29 LDYQCQIKEDAVEQFMFQIKTLRKKNQKYHE--RNSRLKEEQIWHIRHLLKELSEEKA-- 84
++ QC + + ++Q +++ L ++ + +N L+ EQ + R LL+ + +A
Sbjct: 737 IEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFE 796
Query: 85 ----EGLPVVTREDVEEAMKEKWKFE----------RDQEKNLRDMRMQISNAEKLF--L 128
+GL ++++ ++ K E R E +R+++ Q+ AE+ F L
Sbjct: 797 ADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLE-AEQYFSTL 855
Query: 129 EKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKET 188
K KE EE + E + K I LQN+ T+ + K E + +++E
Sbjct: 856 YKTQVKELKEEIEEKNRE-NLKKIQELQNEKETLATQLDLAET--KAESEQLARGLLEEQ 912
Query: 189 LLQLDQK-KEWATQNAVKLIDKGSYLEIWE--NDWLKKEVAIHRKEVEELKNAIHELEAE 245
+L Q+ K+ A++N ++ DK + E N L K++ I R+E EEL + + E E
Sbjct: 913 YFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEE 972
Query: 246 -NLVLIDQLSNCR 257
L +++SN +
Sbjct: 973 YKLEKEEEISNLK 985
Score = 37.0 bits (84), Expect = 0.036
Identities = 52/226 (23%), Positives = 98/226 (43%), Gaps = 27/226 (11%)
Query: 51 RKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTR-EDVEEA-------MKEK 102
++KN + N +LK Q + L +E++E K + + + +EEA M++K
Sbjct: 664 KEKNNLEIDLNYKLKSLQ----QRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKK 719
Query: 103 WKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSL------Q 156
K ER+ + + +QI + L + + E+ ER + +L +
Sbjct: 720 LKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQE 779
Query: 157 NDINTVKENAEKMSEHYKITLEDTRKKIIKE--TLLQLDQKKEWATQNAVKLI--DKGSY 212
++ + +N K L+ K++ +E TLL+ + E+ K ++G
Sbjct: 780 SNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQM 839
Query: 213 LEIWENDWLKKEV---AIHRKEVEELKNAIHELEAENLVLIDQLSN 255
E+ D L+ E +++ +V+ELK I E ENL I +L N
Sbjct: 840 REL--QDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQN 883
Score = 32.7 bits (73), Expect = 0.68
Identities = 47/233 (20%), Positives = 98/233 (42%), Gaps = 29/233 (12%)
Query: 37 EDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTR---- 92
E+ V Q++ L+K +Q NS+L E++ ++ L+E ++ R
Sbjct: 513 ENEVSTLKDQLEDLKKVSQ-----NSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKS 567
Query: 93 -EDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKL 151
++ +++ + R+ ++ R + S +K + + + E + SE L
Sbjct: 568 HTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDL 627
Query: 152 ---ITSLQNDINTVKENAEKM-------------SEHYKITLEDTRKKIIKETLLQLDQK 195
ITSLQ ++ +K N EK+ SE K LE +K +L+Q+
Sbjct: 628 QARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQE 687
Query: 196 KEWATQNAVKLIDKGSYLEIWEN---DWLKKEVAIHRKEVEELKNAIHELEAE 245
+L DK +E ++ ++K++ R+ E+ +N + ++E +
Sbjct: 688 VNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQ 740
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 47.0 bits (110), Expect = 3e-05
Identities = 37/174 (21%), Positives = 77/174 (44%), Gaps = 11/174 (6%)
Query: 59 ERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRM 118
E R +EE++W ++E E+ R++ EE M ++ + R+QE+ +++
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEK---------RQEQEEKMWKQEEKIREQEEKIQEQEE 626
Query: 119 QISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLE 178
+I E+ E+ + EE E+ + +Q T+ EK+ E K E
Sbjct: 627 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686
Query: 179 DTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEV 232
K +E ++Q ++K W + K+ ++ ++ E ++E + +EV
Sbjct: 687 QEEKIREQEEMMQEQEEKMWEQEE--KMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Score = 41.2 bits (95), Expect = 0.002
Identities = 35/171 (20%), Positives = 81/171 (47%), Gaps = 18/171 (10%)
Query: 18 KEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKE--EQIWHIRHL 75
+E K+ E + Q + +++ E+ Q + +R++ +K E+ +++E E+I +
Sbjct: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641
Query: 76 LKELSEEKAEGLPVVTRED--VEEAMKEKWKFE---RDQEKNLRDMRMQISNAEKLFLEK 130
+E E+ E + ++ ++E + W+ E R+QEK +R+ +I E++ E+
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ 701
Query: 131 LSEKEYWEEYKNV---------GSERHAKLITSLQNDINTVKENAEKMSEH 172
E++ WE+ + + E+ + + +++ EKM EH
Sbjct: 702 --EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 39.3 bits (90), Expect = 0.007
Identities = 41/229 (17%), Positives = 101/229 (44%), Gaps = 7/229 (3%)
Query: 18 KEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKY---HERNSRLKEEQIWHIRH 74
+E K+ E ++ ++ + K E+ M++ + ++ ++ E R +EE +W
Sbjct: 333 QEEKMRRQEEMM-WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
Query: 75 LLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEK 134
++EL E+ E + +E+ + ++ + E+ QE+ + R + E+ + EK
Sbjct: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
Query: 135 EYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQ 194
+ W + + + + + Q ++ EK+ E +I K +E ++ +
Sbjct: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQE-EKIHEQEEI-WRQKEKMHEQEEKIRKQE 509
Query: 195 KKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIHELE 243
+K W + ++ ++ E E W ++E ++E+ + +HE E
Sbjct: 510 EKVWRQEEKIREQEE-KIREQEEKMWRQEEKIREQEEMWREEEKMHEQE 557
Score = 37.4 bits (85), Expect = 0.028
Identities = 46/230 (20%), Positives = 93/230 (40%), Gaps = 26/230 (11%)
Query: 18 KEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERN------SRLKEEQIWH 71
KE+K A L Q + + +++++ K Q E N ++ +EE++W
Sbjct: 245 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 304
Query: 72 IRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRM------QISNAEK 125
++E E+ +E E+ +++ K +EK R M ++ E+
Sbjct: 305 QEEKIQEWEEK--------IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 356
Query: 126 LFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRK--- 182
+ EK + EE E+ + + ++E EKM E KI ++ ++
Sbjct: 357 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 416
Query: 183 -KIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKE 231
KI ++ Q + K W + K+ ++ + E ++E IH +E
Sbjct: 417 EKIREQEKRQEQEAKMWRQEE--KIREQEEKIREQEKKMWRQEEKIHEQE 464
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 47.0 bits (110), Expect = 3e-05
Identities = 43/200 (21%), Positives = 89/200 (44%), Gaps = 24/200 (12%)
Query: 52 KKNQKYHERNSRLK--EEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQ 109
++ +K HE+ +++ EE++W EEK RE E+ +++ K R+Q
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWR--------QEEKMHDQEEKIREQEEKVWRQEEKI-REQ 590
Query: 110 EKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKM 169
E+ +R+ +I E++ E+ EE E+ + +Q ++ EK+
Sbjct: 591 EEKIREQEEKIREQEEMTQEQ-------EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 170 SEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAV-----KLIDKGSYLEIWENDWLKKE 224
E K E K +E ++Q ++K W + + K+ ++ + E ++E
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Query: 225 VAIHRKEVEELKNAIHELEA 244
V + ++E E+++ LEA
Sbjct: 704 VRLRQQE-EKMQEHQEHLEA 722
Score = 40.0 bits (92), Expect = 0.004
Identities = 47/224 (20%), Positives = 95/224 (42%), Gaps = 28/224 (12%)
Query: 18 KEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERN------SRLKEEQIWH 71
KE+K A L Q + + +++++ K Q E N ++ +EE++W
Sbjct: 306 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 365
Query: 72 IRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKL 131
++E E+ +E E+ +++ K +EK R M EK+ +
Sbjct: 366 QEEKIQEWEEK--------IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM---RR 414
Query: 132 SEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRK----KIIKE 187
E+ WE+ + + R +++ + I +E EKM E KI ++ ++ KI ++
Sbjct: 415 QEEMMWEKEEKM--RRQEEMMWEKEEKI---RELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 188 TLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKE 231
Q + K W + K+ ++ + E ++E IH +E
Sbjct: 470 EKRQEQEAKMWRQEE--KIREQEEKIREQEEKMWRQEEKIHEQE 511
Score = 35.0 bits (79), Expect = 0.14
Identities = 44/229 (19%), Positives = 101/229 (44%), Gaps = 13/229 (5%)
Query: 18 KEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLK 77
+E K+ E + Q ++ + E+ Q + + +K +K R +EE +W ++
Sbjct: 387 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM-----RRQEEMMWEKEEKIR 441
Query: 78 ELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYW 137
EL E+ E + +E+ + ++ + E+ QE+ + R + E+ + E++ W
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Query: 138 EEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKI-IKETLLQLDQKK 196
+ + + + + Q ++ EK+ E +I + ++KI +E ++ ++K
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQE-EKIREQEEIWRQ--KEKIHEQEEKIRKQEEK 558
Query: 197 EWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKE--VEELKNAIHELE 243
W + K+ D+ + E ++E I +E + E + I E E
Sbjct: 559 MWRQEE--KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE 605
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 46.6 bits (109), Expect = 5e-05
Identities = 38/203 (18%), Positives = 95/203 (46%), Gaps = 11/203 (5%)
Query: 2 ENSGKANKKDTHDGPPKEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERN 61
E + K++ G +E E + + + Q+++ EQ Q + +RK+ ++ E+
Sbjct: 210 EQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE-EQVQKQEEQMRKQEEQMREQE 268
Query: 62 SRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQIS 121
+++E++ ++ ++ +E+ G + EE M+E+ + R+QE+ +R+ Q+
Sbjct: 269 EQMREQEEQMLKQK-EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMG 327
Query: 122 NAEKLFLEKLSE-----KEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKIT 176
E+ E+ + ++ W++ + +G + + + + + +E K E +
Sbjct: 328 KQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE--EQMQKQEEQVRKQEEQMRKQEEQMRKQ 385
Query: 177 LEDTRK--KIIKETLLQLDQKKE 197
E RK + + E Q+ ++KE
Sbjct: 386 EEQMRKQEEQMGEQKEQMGEQKE 408
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 45.8 bits (107), Expect = 8e-05
Identities = 49/224 (21%), Positives = 100/224 (44%), Gaps = 16/224 (7%)
Query: 18 KEIKLPTSEALLDYQCQIKE-DAVEQFMFQIKTLRKKNQKY-----HERNSRLKEEQIWH 71
KE K+ E + Q +I+E + Q +I+ K+ ++ E R +EE+I
Sbjct: 342 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 401
Query: 72 IRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKL 131
+++E E+ E + + EE M+E+ + R QE+ +R+ +I E+ E
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQ--EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE-- 457
Query: 132 SEKEYWEEYKNVGSERHAKLI---TSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKET 188
++E +E + E+ K+ +Q ++ EK+ E K E K +E
Sbjct: 458 -QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Query: 189 LLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEV 232
++Q ++K W + K+ ++ ++ E ++E + +EV
Sbjct: 517 MMQEQEEKMWEQEE--KMCEQEEKMQEQEEKMRRQEEKMREQEV 558
Score = 43.1 bits (100), Expect = 5e-04
Identities = 43/214 (20%), Positives = 95/214 (44%), Gaps = 10/214 (4%)
Query: 37 EDAVEQFMFQIKTLRKKNQKYHERNSRLK--EEQIWHIRHLLKELSEEKAEGLPVVTRED 94
++ E+ Q + +R++ + E+ +++ EE +W ++EL E+ E + +E+
Sbjct: 305 QEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 364
Query: 95 ---VEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKL 151
EE ++E+ K ++QE + +I E+ E+ + EE E+ +
Sbjct: 365 KRQEEEKIREQEK-RQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQ 423
Query: 152 ITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGS 211
+Q ++ EK+ E K E K I+E + +++E + K+ ++ +
Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQEEK--IREQEEMMQEQEEKMGEQEGKMCEQEA 481
Query: 212 YLEIWENDWLKKEVAI--HRKEVEELKNAIHELE 243
++ E ++E I K++ E + I E E
Sbjct: 482 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 515
Score = 42.0 bits (97), Expect = 0.001
Identities = 31/148 (20%), Positives = 71/148 (47%), Gaps = 18/148 (12%)
Query: 41 EQFMFQIKTLRKKNQKYHERNSRLKE--EQIWHIRHLLKELSEEKAEGLPVVTREDV--- 95
E+ Q + +R++ +K E+ +++E E+I +++E E+ E + ++
Sbjct: 425 EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQ 484
Query: 96 --EEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNV---------G 144
EE M+ + + R+QEK +R+ +I E++ E+ E++ WE+ + +
Sbjct: 485 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ--EEKMWEQEEKMCEQEEKMQEQ 542
Query: 145 SERHAKLITSLQNDINTVKENAEKMSEH 172
E+ + ++ +++ EKM EH
Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 35.0 bits (79), Expect = 0.14
Identities = 45/234 (19%), Positives = 100/234 (42%), Gaps = 22/234 (9%)
Query: 18 KEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERN------SRLKEEQIWH 71
KE+K A L Q + + +++++ K Q E N ++ +EE++W
Sbjct: 233 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 292
Query: 72 IRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKL 131
++E EEK + RE E+ +++ +EK R M EK + +L
Sbjct: 293 QEEKIQE-REEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK--IREL 349
Query: 132 SEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQ 191
EK + +E E+ + + ++E ++ + K+ ++ + I+E +
Sbjct: 350 EEKMHEQEKIREQEEK--------RQEEEKIREQEKRQEQEAKMWRQEEK---IREQEEK 398
Query: 192 LDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKE--VEELKNAIHELE 243
+ +++E + K+ ++ + E + ++E + R+E + E + I E E
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQE 452
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 45.8 bits (107), Expect = 8e-05
Identities = 55/219 (25%), Positives = 100/219 (45%), Gaps = 43/219 (19%)
Query: 36 KEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDV 95
K +E+ QI+ L+ + + Y + N+RLKE++ + LLKE +E +
Sbjct: 1034 KSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKE-------------KETL 1080
Query: 96 EEAMKEKWKFERDQEKNLR-DMRMQ-----------ISNAEKLFLEKLSEKEYWEEYKNV 143
+ +KE+ QEKN+ D+++Q ++ + K+ E E E + V
Sbjct: 1081 IQQLKEEL-----QEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKV 1135
Query: 144 GSERHAKL---ITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWAT 200
AKL I ++ I ++ N ++ EH + ++++T+ +KE L KE T
Sbjct: 1136 ECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKL-----KEEIT 1190
Query: 201 QNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAI 239
Q L D L++ E +E +R+E E+LK +
Sbjct: 1191 QLTNNLQDMKHLLQLKE-----EEEETNRQETEKLKEEL 1224
Score = 43.9 bits (102), Expect = 3e-04
Identities = 51/207 (24%), Positives = 96/207 (46%), Gaps = 16/207 (7%)
Query: 67 EQIWHIRHLLKELSEEKAEGLPVVTR---EDVEEAMKEKWKFERDQEKN-----LRDMRM 118
E + L++EL E E V T+ ED+++ ++E F +EK + D++
Sbjct: 527 EDLMEDEDLVEEL-ENAEETQNVETKLLDEDLDKTLEENKAFISHEEKRKLLDLIEDLKK 585
Query: 119 QISNA--EKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYK-- 174
++ N EKL LE +E +E+ ++R A +L + ++ENAE+ +K
Sbjct: 586 KLINEKKEKLTLEFKIREEVTQEFTQYWAQREADFKETLLQEREILEENAERRLAIFKDL 645
Query: 175 ITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEE 234
+ DTR++ K+ + +E +K + L + + +K + + ++E E
Sbjct: 646 VGKCDTREEAAKDICATKVETEEATACLELKFNQIKAELAKTKGELIKTKEELKKRE-NE 704
Query: 235 LKNAIHELEAENLVLIDQLSNCRLVDL 261
+ I ELE N +I Q N R+ +L
Sbjct: 705 SDSLIQELETSNKKIITQ--NQRIKEL 729
Score = 29.3 bits (64), Expect = 7.5
Identities = 57/284 (20%), Positives = 105/284 (36%), Gaps = 35/284 (12%)
Query: 111 KNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMS 170
K +++ R+Q N E F + + WEE K + K + + I +++ EK+
Sbjct: 997 KQVKEYRIQEPNRENSFHSSI--EAIWEECKEI-----VKASSKKSHQIEELEQQIEKLQ 1049
Query: 171 EHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVA--IH 228
K ++ + KE Q D KE K + ++ + + +K V +
Sbjct: 1050 AEVKGYKDENNRLKEKEHKNQDDLLKE-----------KETLIQQLKEELQEKNVTLDVQ 1098
Query: 229 RKEVEELKNAIHELEAENLVLIDQLSNCRLVDLKIPRYPVLHSCPTSNPRHLLLLPLESC 288
+ V E K A+ EL ++ + L+ + HS +L ES
Sbjct: 1099 IQHVVEGKRALSELTQGVTCYKAKIKELETI-LETQKVECSHSAKLEQD----ILEKESI 1153
Query: 289 LISARRCWRLYLTQAAGLEVPPEEMSLELPETHIEEKSELQPTEVESRDLMSSSDESTIL 348
++ R L+ E + + T EL+ E ++ + D +L
Sbjct: 1154 ILKLER----------NLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLL 1203
Query: 349 HLSHENSIEDLQYVKIDKEENSGTEFGDTDMKYLLYEDEKDFKD 392
L E + Q + KEE S + ++K L E+D+ D
Sbjct: 1204 QLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYAD 1247
>gi|100814339 coiled-coil domain containing 146 [Homo sapiens]
Length = 955
Score = 45.8 bits (107), Expect = 8e-05
Identities = 92/461 (19%), Positives = 188/461 (40%), Gaps = 78/461 (16%)
Query: 31 YQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVV 90
+ Q ++ E F ++ +R++ KY + +KE + +H ++ L L EEK +
Sbjct: 104 FHLQQADNFPEAFSTEVSKMREQLLKYQNEYNAVKERE-FHNQYRLNSLKEEKIIIVKEF 162
Query: 91 TREDVEEAMKEKWKFERDQEKNLR-----------DMRMQISNAEKLFLEKLSEKEYWEE 139
+ M++K K R+ + LR ++R +++ +K L++ E E
Sbjct: 163 EKITKPGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLG 222
Query: 140 YKNVGSER---HAKLITSLQNDINTVKENAEKMSEHYKI------TLEDTRKKIIKETLL 190
++ V + H + + +I + +M + + TL D+ KK+ +
Sbjct: 223 HQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSA 282
Query: 191 QLDQKKEWATQNAVKLID-KGSYLEIWE---NDWLKK-EVAIHRKEVEELKNAIHELEAE 245
+D+K +N +K ++ K + LEI E N +K E+A + + I +L
Sbjct: 283 IVDEK-----ENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNLR 337
Query: 246 NLVLI-----DQLS-----------NCRLVDLKIP-RYPVLHSCPTSNPRHLL---LLPL 285
N ++ D+LS N R ++L + + L + R LL +P
Sbjct: 338 NSLIDKQNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPK 397
Query: 286 ESCLISARRCWRLYLTQAAGLEVPPE----EMSLELPETHIEEKSELQPTEVESRDLMSS 341
+ +S RR + A + + EM +L E + E+++L + ++L+ +
Sbjct: 398 DDSTLSERRRELHKEVEVAKRNLAQQKIISEMESKLVEQQLAEENKLLKEQENMKELVVN 457
Query: 342 SDESTILHLSHENSIEDLQYVKIDKEENSGTEFGDTDMKYLLYEDEKDFKDYVNLGPLGV 401
+L ++ +KID++E +F KY E KD +
Sbjct: 458 -----LLRMTQ---------IKIDEKEQKSKDFLKAQQKYTNIVKEMKAKD--------L 495
Query: 402 KLMSVESKKMPIHFQEKEIPVKLYKDVRSPESHITYKMMKS 442
++ + KK I+ + +E KLY +R+ + + K+
Sbjct: 496 EIRIHKKKKCEIYRRLREF-AKLYDTIRNERNKFVNLLHKA 535
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/209 (20%), Positives = 93/209 (44%), Gaps = 29/209 (13%)
Query: 26 EALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAE 85
E L + + +++E E+ Q K LR++ ++ E+ L+E++ + + EEK
Sbjct: 262 ERLREQEGKMREQE-EKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMW 320
Query: 86 GLPVVTREDVEEAMKEK---WKFE---RDQEKNLRDMRMQISNAEKLFLEK----LSEKE 135
RE E+ +++ W+ E R+QE+ +RD ++ ++ EK +++
Sbjct: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 380
Query: 136 YWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQK 195
WE+ + + E ++E +KM E + E K +E + ++
Sbjct: 381 MWEQEEKMQEEER-------------IREREKKMREEEETMREQEEKMQKQEENMWEQEE 427
Query: 196 KEWATQNAVKLIDKGSYLEIWENDWLKKE 224
KEW Q + +K +WE + ++++
Sbjct: 428 KEWQQQRLPEQKEK-----LWEQEKMQEQ 451
Score = 42.0 bits (97), Expect = 0.001
Identities = 37/191 (19%), Positives = 90/191 (47%), Gaps = 10/191 (5%)
Query: 51 RKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTRED---VEEAMKEKWKFER 107
++K + E+ R +EE++W L+E E E + +E+ EE ++E+ K R
Sbjct: 343 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMR 402
Query: 108 DQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAE 167
++E+ +R+ ++ E+ E+ E++ W++ + + +Q + E E
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQ--EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Query: 168 KMSEHYKITLEDT---RKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKE 224
K+ + ++ ++ R++ ++E Q+ +++E K+ D+ +WE D +E
Sbjct: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE--RMWEQDERLRE 518
Query: 225 VAIHRKEVEEL 235
+E +++
Sbjct: 519 KEERMREQKKM 529
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/210 (19%), Positives = 92/210 (43%), Gaps = 30/210 (14%)
Query: 34 QIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTRE 93
Q++ + +++ M++ +++ + E+ R +EE++W L+E + E
Sbjct: 226 QVQTNTLQEEMWR----QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ------- 274
Query: 94 DVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLIT 153
EE M+ + K R+QEK LR+ ++ +KL ++E +E + E+ K+
Sbjct: 275 --EEKMRRQEKRLREQEKELREQEKELREQKKL----REQEEQMQEQEEKMWEQEEKM-- 326
Query: 154 SLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYL 213
+E EKM + E ++ +E ++ +++ W + +L +K +
Sbjct: 327 ---------REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW--EQDERLREKEERM 375
Query: 214 EIWENDWLKKEVAIHRKEVEELKNAIHELE 243
E W ++E + + E + + E E
Sbjct: 376 REQEKMWEQEEKMQEEERIREREKKMREEE 405
Score = 41.2 bits (95), Expect = 0.002
Identities = 44/244 (18%), Positives = 107/244 (43%), Gaps = 38/244 (15%)
Query: 2 ENSGKANKKDTHDGPPKEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERN 61
E + +K T D +E K+ E + + + +++E+ + +R++ +K E+
Sbjct: 539 EKKTQEQEKKTWD---QEEKMREEERMREREKKMREEE--------EMMREQEEKMQEQE 587
Query: 62 SRLK--EEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQ 119
+++ EE++W ++E E+ E + ++ E+ M+E+ + +QE+ +++ +
Sbjct: 588 EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Query: 120 ISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLED 179
+ E EK+ E+E E+ + +Q ++E EKM + E
Sbjct: 648 MWEQE----EKMREQE----------EKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693
Query: 180 TRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAI 239
K +E + ++K W G ++W + ++++ R + E+++ +
Sbjct: 694 EEKMRGQEEKMWGQEEKMW-----------GQEEKMWGQEEMREKEERIRDQKEKMQERL 742
Query: 240 HELE 243
E E
Sbjct: 743 PEHE 746
Score = 39.7 bits (91), Expect = 0.006
Identities = 37/179 (20%), Positives = 83/179 (46%), Gaps = 8/179 (4%)
Query: 18 KEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLK 77
+E K+ E + Q + + E+ Q K +++ + E+ ++ +E++ W ++
Sbjct: 498 QEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMR 557
Query: 78 ELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYW 137
E EE+ RE+ EE M+E+ + ++QE+ +R+ ++ E+ E+ E++ W
Sbjct: 558 E--EERMREREKKMREE-EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ--EEKMW 612
Query: 138 EEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKK 196
E+ + + + +Q + E EKM E + E K +E ++ ++K
Sbjct: 613 EQEEKMWEQEEE---DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Score = 39.7 bits (91), Expect = 0.006
Identities = 42/211 (19%), Positives = 100/211 (47%), Gaps = 20/211 (9%)
Query: 41 EQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMK 100
E+ M + K +++ +K ++ +++EE+ +R K++ EE+ + RE EE M+
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEE--RMREREKKMREEEE-----MMREQ-EEKMQ 584
Query: 101 EKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLI----TSLQ 156
E+ + R+QE+ + + ++ E+ E+ E++ WE+ + + +++ +Q
Sbjct: 585 EQEEKMREQEEKMWEQEEKMQEQEEKMWEQ--EEKMWEQEEEDKMQEQEEMMWEQEEKMQ 642
Query: 157 NDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLID---KGSYL 213
+ E EKM E + E K +E ++ ++K + ++ + +G
Sbjct: 643 EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEE 702
Query: 214 EIW---ENDWLKKEVAIHRKEVEELKNAIHE 241
++W E W ++E ++E+ E + I +
Sbjct: 703 KMWGQEEKMWGQEEKMWGQEEMREKEERIRD 733
Score = 38.9 bits (89), Expect = 0.009
Identities = 49/215 (22%), Positives = 90/215 (41%), Gaps = 21/215 (9%)
Query: 50 LRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFE--- 106
L+KKN + E+ RL E + I+ +KEL + ++ + +E W+ E
Sbjct: 185 LKKKNAELQEK-LRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 243
Query: 107 RDQEKNLRDMRMQISNAEKLFLE------------KLSEKEYWEEYKNV-GSERHAKLIT 153
R+QEK +R ++ E+ E + EK E+ K + E+ +
Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK 303
Query: 154 SLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYL 213
L+ ++E EKM E + E K +E L +Q+K+ Q K+ D+
Sbjct: 304 KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL-WEQEKQMREQEQ-KMRDQEE-- 359
Query: 214 EIWENDWLKKEVAIHRKEVEELKNAIHELEAENLV 248
+WE D +E +E E++ +++ E +
Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 45.1 bits (105), Expect = 1e-04
Identities = 54/228 (23%), Positives = 104/228 (45%), Gaps = 31/228 (13%)
Query: 60 RNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTR---EDVEEAMKEKWKFERDQEKNLR-- 114
R S L E + H + EL+ + L + + + VEE E + K L+
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497
Query: 115 -DMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHY 173
+ + E L E + EK+ + +N+ + K L+ I T++EN+E+
Sbjct: 498 KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDL-MKEKAQLEKTIETLRENSER----- 551
Query: 174 KITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKG---------------SYLEIWEN 218
+I + + + + +T+ L Q+ + + + VK I+K S +E +E
Sbjct: 552 QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIE-FEK 610
Query: 219 DWLKKEVAIHRKE---VEELKNAIHELEAENLVLIDQLSNCRLVDLKI 263
+KKE+ ++++ EEL+N +H LE EN +L +++N ++ KI
Sbjct: 611 RQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKI 658
Score = 42.7 bits (99), Expect = 7e-04
Identities = 53/238 (22%), Positives = 106/238 (44%), Gaps = 42/238 (17%)
Query: 35 IKEDA--VEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKE--LSEEKAEGLPVV 90
IKE + + + F+ + ++K+ + Y E+ R +E + + HL KE L ++K L +
Sbjct: 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELEN-ELHHLEKENELLQKKITNLKI- 653
Query: 91 TREDVEEAMKEKWKFERDQEK------NLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVG 144
T E +E +E + ER+ K + +++ Q+ + EK ++E E +NV
Sbjct: 654 TCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE--NSQLDEENLELRRNVE 711
Query: 145 SERHAKL-ITSLQ---NDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWAT 200
S + A + + LQ ++ + KE +K E K + + T + + L +
Sbjct: 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI-------- 763
Query: 201 QNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIHELEAENLVLIDQLSNCRL 258
EN L+K + K++++L++ + +LE EN L L ++
Sbjct: 764 ----------------ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKI 805
Score = 41.2 bits (95), Expect = 0.002
Identities = 57/261 (21%), Positives = 110/261 (42%), Gaps = 27/261 (10%)
Query: 1 MENSGKANKKDTHDGPPKEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHER 60
+E K+ +++T + +L L Q +IK+ +E+ +I L K+N+ +
Sbjct: 813 LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Query: 61 NSRLKEEQIWHIRHLLKELSEEKAEGLP---------VVTREDVEEAMKEKWKFERDQEK 111
KE + LKEL +E E + V RED+ + + D EK
Sbjct: 873 IGIYKESCV-----RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEK 927
Query: 112 NLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSL---QNDINTVKENAEK 168
++ N E+L ++ S + YK + S+ + L SL + I ++ E+
Sbjct: 928 LTHELEKIGLNKERLLHDEQSTDD--SRYKLLESKLESTLKKSLEIKEEKIAALEARLEE 985
Query: 169 MSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIH 228
S +Y L K +K+ L Q+ Q+ +++ + +N W ++E
Sbjct: 986 -STNYNQQLRQ-ELKTVKKNYEALKQR-----QDEERMVQSSPPISGEDNKW-ERESQET 1037
Query: 229 RKEVEELKNAIHELEAENLVL 249
+E+ ++K+ + E+E N L
Sbjct: 1038 TRELLKVKDRLIEVERNNATL 1058
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 45.1 bits (105), Expect = 1e-04
Identities = 54/228 (23%), Positives = 104/228 (45%), Gaps = 31/228 (13%)
Query: 60 RNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTR---EDVEEAMKEKWKFERDQEKNLR-- 114
R S L E + H + EL+ + L + + + VEE E + K L+
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497
Query: 115 -DMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHY 173
+ + E L E + EK+ + +N+ + K L+ I T++EN+E+
Sbjct: 498 KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDL-MKEKAQLEKTIETLRENSER----- 551
Query: 174 KITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKG---------------SYLEIWEN 218
+I + + + + +T+ L Q+ + + + VK I+K S +E +E
Sbjct: 552 QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIE-FEK 610
Query: 219 DWLKKEVAIHRKE---VEELKNAIHELEAENLVLIDQLSNCRLVDLKI 263
+KKE+ ++++ EEL+N +H LE EN +L +++N ++ KI
Sbjct: 611 RQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKI 658
Score = 42.7 bits (99), Expect = 7e-04
Identities = 53/238 (22%), Positives = 106/238 (44%), Gaps = 42/238 (17%)
Query: 35 IKEDA--VEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKE--LSEEKAEGLPVV 90
IKE + + + F+ + ++K+ + Y E+ R +E + + HL KE L ++K L +
Sbjct: 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELEN-ELHHLEKENELLQKKITNLKI- 653
Query: 91 TREDVEEAMKEKWKFERDQEK------NLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVG 144
T E +E +E + ER+ K + +++ Q+ + EK ++E E +NV
Sbjct: 654 TCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE--NSQLDEENLELRRNVE 711
Query: 145 SERHAKL-ITSLQ---NDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWAT 200
S + A + + LQ ++ + KE +K E K + + T + + L +
Sbjct: 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI-------- 763
Query: 201 QNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIHELEAENLVLIDQLSNCRL 258
EN L+K + K++++L++ + +LE EN L L ++
Sbjct: 764 ----------------ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKI 805
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/261 (21%), Positives = 110/261 (42%), Gaps = 28/261 (10%)
Query: 1 MENSGKANKKDTHDGPPKEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHER 60
+E K+ +++T + +L L Q +IK+ +E+ +I L K+N+ +
Sbjct: 813 LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Query: 61 NSRLKEEQIWHIRHLLKELSEEKAEGLP---------VVTREDVEEAMKEKWKFERDQEK 111
KE + LKEL +E E + V RED+ + + D EK
Sbjct: 873 IGIYKESCV-----RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEK 927
Query: 112 NLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSL---QNDINTVKENAEK 168
++ N E+L ++ S + YK + S+ + L SL + I ++ E+
Sbjct: 928 LTHELEKIGLNKERLLHDEQSTD---DRYKLLESKLESTLKKSLEIKEEKIAALEARLEE 984
Query: 169 MSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIH 228
S +Y L K +K+ L Q+ Q+ +++ + +N W ++E
Sbjct: 985 -STNYNQQLRQ-ELKTVKKNYEALKQR-----QDEERMVQSSPPISGEDNKW-ERESQET 1036
Query: 229 RKEVEELKNAIHELEAENLVL 249
+E+ ++K+ + E+E N L
Sbjct: 1037 TRELLKVKDRLIEVERNNATL 1057
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 44.7 bits (104), Expect = 2e-04
Identities = 43/175 (24%), Positives = 87/175 (49%), Gaps = 10/175 (5%)
Query: 82 EKAEGLPVVTREDVEE---AMKEKWKFERDQEKNLRDMRMQISNAEKLFLE-KLSEKEYW 137
E+ E L + R VE+ +EK + +++EK + D+R + AE L + K E +
Sbjct: 416 EQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLL 475
Query: 138 EEYKNV--GSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQK 195
KN+ + K++ + +I K ++ + + E+T + +KET L Q+
Sbjct: 476 VGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLE--LKETYSSLQQE 533
Query: 196 KEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAI-HELEAENLVL 249
+ T+ KL K ++ +D L++E R+E+E+ +N + EL+ ++L++
Sbjct: 534 VDIKTKKLKKLFSKLQAVKAEIHD-LQEEHIKERQELEQTQNELTRELKLKHLII 587
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 44.3 bits (103), Expect = 2e-04
Identities = 51/236 (21%), Positives = 102/236 (43%), Gaps = 43/236 (18%)
Query: 36 KEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKEL--SEEKAEGLP---VV 90
+ED +E+F + + L++ N + + N L E + L K+L +EEKA+ L ++
Sbjct: 831 QEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLM 890
Query: 91 TREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAK 150
T++ + +A +EK + E + + R ++ AE + S +++ + SER K
Sbjct: 891 TKQKLIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEK 950
Query: 151 LITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKG 210
T+ + +I +++ + + ++ R K I T LD+ +
Sbjct: 951 QQTANKVEIEKIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTD------------- 997
Query: 211 SYLEIWENDWLKKEVAIHRKEVEELKNAIHELEAE----NLVLIDQLSNCRLVDLK 262
+E E LKN + E+E E L L++ + C++ DL+
Sbjct: 998 -------------------EEKETLKNQLREMELELAQTKLQLVE--AECKIQDLE 1032
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 43.9 bits (102), Expect = 3e-04
Identities = 50/239 (20%), Positives = 108/239 (45%), Gaps = 31/239 (12%)
Query: 36 KEDAVEQFMFQIKTLRKKNQKYHERNSRLKEE--QIWHIRHLLKELSEEKAEGLPVVTRE 93
KED+ + + ++++LR++ Q+ + + L+EE ++W E + AE R+
Sbjct: 1354 KEDSEHRLVLELESLRRQLQQAAQEQAALREECTRLWS----RGEATATDAEAREAALRK 1409
Query: 94 DVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLIT 153
+VE+ KE+ + + EK+ + Q+ E E+LS+ G + A+ +T
Sbjct: 1410 EVEDLTKEQSETRKQAEKDRSALLSQMKILESELEEQLSQHR--------GCAKQAEAVT 1461
Query: 154 SLQNDINTVKE---NAEKMSEHYKITLEDTRKKIIKE------TLLQLDQKKEWATQNAV 204
+L+ + ++ + N + + E R++ +E L Q + + W +++
Sbjct: 1462 ALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEGQLRQAAKPQPWGPRDSQ 1521
Query: 205 KLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIHELEAENLVLIDQLSNCRLVDLKI 263
+ G E + L++++ E EL AI + A+ VL+ + RL ++ I
Sbjct: 1522 QAPLDG------EVELLQQKLREKLDEFNEL--AIQKESADRQVLMQEEEIKRLEEMNI 1572
Score = 29.3 bits (64), Expect = 7.5
Identities = 44/177 (24%), Positives = 79/177 (44%), Gaps = 16/177 (9%)
Query: 73 RHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLS 132
+H L+ L E+ A V +EA + K K + + EKN + ++ + E S
Sbjct: 300 QHELELLREQHAREKEEVVLRCGQEAAELKEKLQSEMEKNAQIVKTLKEDWE-------S 352
Query: 133 EKEY-WEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQ 191
EK+ E + S +H + LQN KE AE+ +E KI + K + L
Sbjct: 353 EKDLCLENLRKELSAKHQSEMEDLQNQFQ--KELAEQRAELEKIFQD---KNQAERALRN 407
Query: 192 LDQKKEWATQNAVKLI--DKGSYLEIWENDWLKKEVAIHRKEVEELKNAIHELEAEN 246
L+ + A + + + + G LE E + + E + E+E L+ + +L+A++
Sbjct: 408 LESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKE-KQLELENLQASYEDLKAQS 463
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/239 (22%), Positives = 104/239 (43%), Gaps = 41/239 (17%)
Query: 51 RKKNQKYH---------ERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVT----REDVEE 97
++K +K H E N +L ++Q I+HL +E K+E L + T R+ +EE
Sbjct: 691 QEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEE 750
Query: 98 AMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQN 157
E + + ++D + Q+S E + EKE KN ++ Q+
Sbjct: 751 QTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNK-------IAQD 803
Query: 158 DINTVKENAEKM--------------SEHYKITLEDTRKKIIKETLLQLDQKKEWATQNA 203
+N +KE + + + YK E K+I + L + ++ KE ++
Sbjct: 804 KLNDIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQ-LSECEKHKEKINED- 861
Query: 204 VKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIHELEAENLVLIDQLSNCRLVDLK 262
++L+ + + + WL+ + + RK EELK E+E E + ++ +++ +K
Sbjct: 862 MRLMRQDIDTQKIQERWLQDNLTL-RKRNEELK----EVEEERKQHLKEMGQMQVLQMK 915
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/239 (22%), Positives = 104/239 (43%), Gaps = 41/239 (17%)
Query: 51 RKKNQKYH---------ERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVT----REDVEE 97
++K +K H E N +L ++Q I+HL +E K+E L + T R+ +EE
Sbjct: 830 QEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEE 889
Query: 98 AMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQN 157
E + + ++D + Q+S E + EKE KN ++ Q+
Sbjct: 890 QTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNK-------IAQD 942
Query: 158 DINTVKENAEKM--------------SEHYKITLEDTRKKIIKETLLQLDQKKEWATQNA 203
+N +KE + + + YK E K+I + L + ++ KE ++
Sbjct: 943 KLNDIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQ-LSECEKHKEKINED- 1000
Query: 204 VKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIHELEAENLVLIDQLSNCRLVDLK 262
++L+ + + + WL+ + + RK EELK E+E E + ++ +++ +K
Sbjct: 1001 MRLMRQDIDTQKIQERWLQDNLTL-RKRNEELK----EVEEERKQHLKEMGQMQVLQMK 1054
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 43.5 bits (101), Expect = 4e-04
Identities = 74/368 (20%), Positives = 160/368 (43%), Gaps = 59/368 (16%)
Query: 37 EDAVEQFMFQIKTLRKKNQKYHERNSRLKEE------QIWHIRHLLKELSEEKAEGLPVV 90
++A E+ + ++TL+++N+ + S L E+ I + + K+L EK+E
Sbjct: 1489 KNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSE----- 1543
Query: 91 TREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAK 150
+ +EEA + E ++ K LR ++++++ + K++EK+ EE + H +
Sbjct: 1544 LQTSLEEA---EASLEHEEGKILR-IQLELNQVKSEIDRKIAEKD--EELDQL-KRNHLR 1596
Query: 151 LITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKG 210
++ S+Q+ + +AE S + + ++ + + E +QL+ A + L +
Sbjct: 1597 VVESMQSTL-----DAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQ 1651
Query: 211 SYLE---------IWENDWLKKEVAIHRKEVEELKNAIHELEA--ENLVLIDQLSNCRLV 259
L+ I D LK+++A+ + ++ + EL A E +++ L+
Sbjct: 1652 GILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELL 1711
Query: 260 DLKIPRYPVLHSCPTSNPRHLLLLPLESCLISARRCWRLYLTQAAGLEVPPEEMSLELPE 319
D R +LH+ TS LI+ ++ ++Q G E +
Sbjct: 1712 DAS-ERVQLLHTQNTS-------------LINTKKKLETDISQIQG-----EMEDIVQEA 1752
Query: 320 THIEEKSELQPTEVESRDLMSSSDESTILHLSH-----ENSIEDLQYVKIDKEENSGTEF 374
+ EEK++ T+ ++ T HL E +++DLQ +++D+ E +
Sbjct: 1753 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ-LRLDEAEQLALKG 1811
Query: 375 GDTDMKYL 382
G ++ L
Sbjct: 1812 GKKQIQKL 1819
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 43.1 bits (100), Expect = 5e-04
Identities = 60/247 (24%), Positives = 120/247 (48%), Gaps = 35/247 (14%)
Query: 25 SEALLDYQCQIKE------DAVEQFMFQIKTLR--KKNQKYHERNSRLKEEQIWHIRHLL 76
SE + Q Q++E + EQ FQ + KK Q+ E+ EEQI +++ L
Sbjct: 146 SEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQL 205
Query: 77 KELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEY 136
++EK E V +++ EA + + +KN+ ++ ++ + + E++ KE
Sbjct: 206 DATTDEKKE--TVTQLQNIIEANSQHY------QKNINSLQEELLQLKAIHQEEV--KEL 255
Query: 137 WEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKK 196
+ + E A++ N +N +KEN K E + K I K+ +L+ +
Sbjct: 256 MCQIEASAKEHEAEI-----NKLNELKENLVKQCEA-------SEKNIQKKYECELENLR 303
Query: 197 EWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIHELEAENLVLIDQLSNC 256
+ AT NA + S L + EN ++++ V ++V+ L++ + ELE+++ +L D+++
Sbjct: 304 K-ATSNANQDNQICSIL-LQENTFVEQVV---NEKVKHLEDTLKELESQHSILKDEVTYM 358
Query: 257 RLVDLKI 263
+ LK+
Sbjct: 359 NNLKLKL 365
Score = 40.0 bits (92), Expect = 0.004
Identities = 41/225 (18%), Positives = 98/225 (43%), Gaps = 19/225 (8%)
Query: 29 LDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLP 88
L+ + +I++ E +I +L+ Q+Y E+N+++K+ LL + +E A
Sbjct: 1186 LEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQ--------LLVKTKKELA---- 1233
Query: 89 VVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERH 148
D ++A + + + L + Q+ + E SEK E+ +E+H
Sbjct: 1234 -----DSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQH 1288
Query: 149 AKLITSLQNDINTVKENAE-KMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLI 207
+ +++ Q + ++E +E +T E K+ +L+ + K +
Sbjct: 1289 QRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAK 1348
Query: 208 DKGSYLEIWENDWLKKEVAIHRKEVEELKNAIHELEAENLVLIDQ 252
+ +LE+ D LK ++ + ++ + + L++E+ L+++
Sbjct: 1349 QEREHLEML-IDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLER 1392
Score = 39.3 bits (90), Expect = 0.007
Identities = 51/248 (20%), Positives = 101/248 (40%), Gaps = 16/248 (6%)
Query: 9 KKDTHDGPPKEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHE-------RN 61
KK+ D E +A L + + + VE + Q+ + + K HE ++
Sbjct: 1229 KKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQH 1288
Query: 62 SRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQIS 121
R + L +E KAE VT E ++ ++ + K++ + +
Sbjct: 1289 QRTLSAYQQRVTALQEECRAAKAEQA-TVTSEFESYKVRVHNVLKQQKNKSMSQAETEGA 1347
Query: 122 NAEKLFLEKLSEKEYWEEYKNVGSERHAKL----ITSLQNDINTVKENAEKMSEHYKITL 177
E+ LE L ++ + K S+ + ++ + +LQ++ +T+ E KM +
Sbjct: 1348 KQEREHLEMLIDQL---KIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKE 1404
Query: 178 EDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKN 237
+ R+K+ + K E TQ +L + L D ++ HRK VE L+
Sbjct: 1405 AELREKLCSIQSENMMMKSEH-TQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQ 1463
Query: 238 AIHELEAE 245
+ ++EA+
Sbjct: 1464 QLSKMEAQ 1471
Score = 36.6 bits (83), Expect = 0.047
Identities = 54/235 (22%), Positives = 98/235 (41%), Gaps = 48/235 (20%)
Query: 41 EQFMFQIKTLRKKNQKYH---ERNSRL------KEEQIWHIRHLLKELSEEKAEGLPVVT 91
+ F+ ++K ++ +H ER RL K EQ L++ E GL
Sbjct: 597 DDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGL---- 652
Query: 92 REDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKL 151
EE +KEK + ++ EK + M++ + E L E K +EE + SE+
Sbjct: 653 ----EETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEV---KSLYEENNKLSSEK---- 701
Query: 152 ITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQ---NAVKLID 208
+++S ++ L I+KE + QL++K + + N KL++
Sbjct: 702 ---------------KQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLE 746
Query: 209 KGSYLEIWENDWL---KKEVAIHRKEVEELKNAIHELEA--ENLVLIDQLSNCRL 258
+++ L KE+ E E K+ ++ L+A E+L I++ C L
Sbjct: 747 NEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINE-EKCNL 800
Score = 34.3 bits (77), Expect = 0.23
Identities = 46/208 (22%), Positives = 88/208 (42%), Gaps = 36/208 (17%)
Query: 64 LKEE---QIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERD------------ 108
L+EE Q ++ LL++ +EK V+ R+++EE EK + D
Sbjct: 818 LQEESVVQCEELKSLLRDYEQEK-----VLLRKELEEIQSEKEALQSDLLEMKNANEKTR 872
Query: 109 -QEKNLRDMRMQISNA-EKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENA 166
+ +NL ++S K + EK + +E++N+ K + + ++ +K++
Sbjct: 873 LENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSL 932
Query: 167 EKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVA 226
K L ++ K L+ + K++ N +KL+ + KKE+
Sbjct: 933 AKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKA----------KKELD 982
Query: 227 IHRKEVEELKNAIHELEAENLVLIDQLS 254
RKE + +K + L +E DQLS
Sbjct: 983 SSRKETQTVKEELESLRSEK----DQLS 1006
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 43.1 bits (100), Expect = 5e-04
Identities = 72/355 (20%), Positives = 140/355 (39%), Gaps = 23/355 (6%)
Query: 46 QIKTLRKKNQKYHERNSRLKEEQIWH---IRHLLKELSEEKAEGLPVVTREDVEEAMKEK 102
+++T +K K E + +EE + + + SEEKAE P +D E K+K
Sbjct: 258 ELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE-TPTAAEDDNEGDKKKK 316
Query: 103 WKFERDQEKNLRDMRMQISNAE---KLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDI 159
K ++ EK ++ + ++ K E L++ + EE + E K + L+
Sbjct: 317 DKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKR 376
Query: 160 NTVKENAEKMSEHYKITLEDTRKKIIKE-TLLQLDQKKEWATQNAVKLIDKGSYLEIWEN 218
+ ++ E K ++ ++++ KE LL Q++ A A + + +E+
Sbjct: 377 KEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSK 436
Query: 219 DWLKKEVAIHRKEVEELKNAIHELEAENLVLIDQLSNCRLVDLKIPRYPVLHSCPTS-NP 277
D L K+ I+ E ++ K +LE++ + + + C V++ P P P
Sbjct: 437 DSLPKKRPIY--EDKKRKKIPQQLESKEVS--ESMELCAAVEVMEQGVPEKEETPPPVEP 492
Query: 278 RHLLLLPLESCLISARRCWRLYLTQAAGLEVPPEEMSLELPETHIEEKSELQPTEVESRD 337
E + W + +V ++ +E+ E EE+ E + E +
Sbjct: 493 EEE-----EDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEES 547
Query: 338 LMSSSDESTILHLSHENSIEDLQYVKIDKEENSGTEFGDTDMKYLLYEDEKDFKD 392
+E E S D + K+ E++SG K + + E D D
Sbjct: 548 EEEEEEEG-----ESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDD 597
Score = 38.9 bits (89), Expect = 0.009
Identities = 84/386 (21%), Positives = 155/386 (40%), Gaps = 39/386 (10%)
Query: 38 DAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTRE-DVE 96
D ++F+ Q + +KKNQK + + +K ++++KAE ++ D E
Sbjct: 188 DESDEFL-QSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEE 246
Query: 97 EAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQ 156
+A K K + + E +D Q + K E + K + SE A+ T+ +
Sbjct: 247 KAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAE 306
Query: 157 NDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIW 216
+D K+ +K +KK KE + +KK+ ++ VK + +
Sbjct: 307 DDNEGDKKKKDKK-----------KKKGEKEE--KEKEKKKGPSKATVKAMQEALAK--- 350
Query: 217 ENDWLKKEVAIHRKEVEELKNAIHELEAENLV--LIDQLSNCRLVDLKIPRYPVLHSCPT 274
LK+E ++E EE + ELEA+ ++Q R + R L
Sbjct: 351 ----LKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLK---- 402
Query: 275 SNPRHLLLLPLESCLISARRCWRLYLTQAAGLEVPPEEMSLELPETHIEEKSELQPTEVE 334
+ LL AR L L QA G+EVP ++ + + ++K + P ++E
Sbjct: 403 ---KEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLE 459
Query: 335 SRDLMSSSDESTILHLSHENSIEDLQY-VKIDKEENSGTEFGDTDMKYLLYEDEKDFKDY 393
S+++ S + + + + E + ++ EE TE D + DE+ K
Sbjct: 460 SKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVE 519
Query: 394 VNLGPLGVKLMSVESKKMPIHFQEKE 419
N + +E K+ P +E+E
Sbjct: 520 GN-------KVHIEVKENPEEEEEEE 538
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 42.7 bits (99), Expect = 7e-04
Identities = 107/451 (23%), Positives = 190/451 (42%), Gaps = 88/451 (19%)
Query: 34 QIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKE---LSEEKAE-GLPV 89
Q DA + M ++ +L + N E N +LK I L KE LS+EK E + +
Sbjct: 392 QALSDAENEIM-RLSSLNQDNS-LAEDNLKLK----MRIEVLEKEKSLLSQEKEELQMSL 445
Query: 90 VTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYW----EEY--KNV 143
+ + E +K + + L D+R+ + E+ + +SEKE EE +N
Sbjct: 446 LKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQ 505
Query: 144 GSERHAKLI----TSLQND----INTVKE--NAEKMSEHYKITLEDTRKKIIKETLLQLD 193
+ +H LI + QN+ I+ +K+ N EK H LED + I KE +Q +
Sbjct: 506 EATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVH---QLEDDKMDITKELDVQKE 562
Query: 194 ----------------QKKEWATQNAVKLIDKGSYLEI---WENDWLKKEVAIHRKEVEE 234
QK E +N V ++K + EN LK+ + + +E+
Sbjct: 563 KLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSR 622
Query: 235 LKN-----------------AIHELEAE------NLVLIDQLS-NCRLV--DLKIPRYPV 268
++N + E EAE NL ++QL+ N + V D+K+ +
Sbjct: 623 IRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKL 682
Query: 269 LHSCPTSNPRHLLLLPLESCLISARRCWRLYLTQAAGLEVPPEEMSLEL---PETHIEEK 325
+ +C + RH LE CL + T L++ E+ EL + +EE
Sbjct: 683 VLAC--EDVRH----QLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEA 736
Query: 326 SELQPTEVE---SRDLMSSSDESTILHLSHENSIEDLQYVKIDKE-ENSGTEFGDT-DMK 380
++ + T E +R+L +S+ + HL N +D++ ++ K E T+ +T D+
Sbjct: 737 NKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVL 796
Query: 381 YLLYEDEKDFKDYVNLGPLGVKLMSVESKKM 411
E++K +N + ++ + S K+
Sbjct: 797 SSSLEEQKQLTQLINKKEIFIEKLKERSSKL 827
Score = 37.4 bits (85), Expect = 0.028
Identities = 42/194 (21%), Positives = 89/194 (45%), Gaps = 37/194 (19%)
Query: 55 QKYHERNSRLKEE-----QIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQ 109
+K ER+S+L+EE Q +L++ EEK L +MKE+ +++
Sbjct: 818 EKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLG---------SMKEENNHLQEE 868
Query: 110 EKNLRDMRMQISN-AEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEK 168
+ LR+ + + + A+ L+ ++E + S + +NT+KE+ E+
Sbjct: 869 LERLREEQSRTAPVADPKTLDSVTE------------------LASEVSQLNTIKEHLEE 910
Query: 169 MSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIW-ENDWLKKEVAI 227
+H++ +ED + ++ +QKKE ++ +++ E D +E+
Sbjct: 911 EIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKD---EEIKS 967
Query: 228 HRKEVEELKNAIHE 241
+K +E++K +HE
Sbjct: 968 LQKTIEQIKTQLHE 981
Score = 35.8 bits (81), Expect = 0.080
Identities = 61/267 (22%), Positives = 107/267 (40%), Gaps = 47/267 (17%)
Query: 8 NKKDTHDGPPKEIKLPTSEALLDYQCQIKED-----AVEQFMFQIKTLRKKNQKYHERNS 62
NKK+ KE E L Y ++++ +E+ + +++++N E
Sbjct: 811 NKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELE 870
Query: 63 RLKEEQ-----------IWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEK 111
RL+EEQ + + L E+S+ +E +EE +K K DQ +
Sbjct: 871 RLREEQSRTAPVADPKTLDSVTELASEVSQLN------TIKEHLEEEIKHHQKIIEDQNQ 924
Query: 112 NLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSE 171
+ +MQ+ + + +++ E Y E N H +L +I ++ +K E
Sbjct: 925 S----KMQLLQSLQEQKKEMDEFRYQHEQMNA---THTQLFLEKDEEIKSL----QKTIE 973
Query: 172 HYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKL-IDKGSYLEIWENDWLKKEVAIHRK 230
K L + R+ I Q D + L I+ GS ++D K E K
Sbjct: 974 QIKTQLHEERQDI------QTDNSDIFQETKVQSLNIENGSE----KHDLSKAETERLVK 1023
Query: 231 EVEELKNAIHELEAENLVL---IDQLS 254
++E + I L +N+ L IDQLS
Sbjct: 1024 GIKERELEIKLLNEKNISLTKQIDQLS 1050
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,353,344
Number of Sequences: 37866
Number of extensions: 814806
Number of successful extensions: 3969
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 487
Number of HSP's that attempted gapping in prelim test: 3242
Number of HSP's gapped (non-prelim): 1091
length of query: 444
length of database: 18,247,518
effective HSP length: 105
effective length of query: 339
effective length of database: 14,271,588
effective search space: 4838068332
effective search space used: 4838068332
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.