Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 40254949
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40254949 erythrocyte membrane protein band 4.1 like 5 [Homo
sapiens]
(733 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40254949 erythrocyte membrane protein band 4.1 like 5 [Homo s... 1459 0.0
gi|110624790 erythrocyte membrane protein band 4.1 like 4B isofo... 580 e-165
gi|110624794 erythrocyte membrane protein band 4.1 like 4B isofo... 553 e-157
gi|207113199 erythrocyte membrane protein band 4.1-like 2 isofor... 292 9e-79
gi|207113195 erythrocyte membrane protein band 4.1-like 2 isofor... 292 9e-79
gi|4503579 erythrocyte membrane protein band 4.1-like 2 isoform ... 292 9e-79
gi|87042275 erythrocyte protein band 4.1-like 4 [Homo sapiens] 288 2e-77
gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform... 282 9e-76
gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform... 280 4e-75
gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo s... 278 1e-74
gi|42716291 erythrocyte membrane protein band 4.1 (elliptocytosi... 274 2e-73
gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis... 274 2e-73
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho... 269 8e-72
gi|94721308 FERM domain containing 5 isoform 2 [Homo sapiens] 256 5e-68
gi|117500790 FERM domain containing 3 [Homo sapiens] 255 9e-68
gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosi... 230 3e-60
gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform... 229 7e-60
gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo sa... 213 7e-55
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i... 212 1e-54
gi|223941876 protein tyrosine phosphatase, non-receptor type 3 i... 207 4e-53
gi|34916000 FERM domain containing 7 [Homo sapiens] 189 8e-48
gi|239754880 PREDICTED: similar to hCG2040198 [Homo sapiens] 170 4e-42
gi|239749418 PREDICTED: similar to hCG2040198 [Homo sapiens] 170 4e-42
gi|239743554 PREDICTED: similar to hCG2040198 [Homo sapiens] 170 4e-42
gi|150418005 protein tyrosine phosphatase, non-receptor type 21 ... 139 1e-32
gi|161702986 ezrin [Homo sapiens] 132 9e-31
gi|21614499 ezrin [Homo sapiens] 132 9e-31
gi|34328899 protein tyrosine phosphatase, non-receptor type 14 [... 132 9e-31
gi|4506467 radixin [Homo sapiens] 132 1e-30
gi|38788243 myosin regulatory light chain interacting protein [H... 127 3e-29
>gi|40254949 erythrocyte membrane protein band 4.1 like 5 [Homo
sapiens]
Length = 733
Score = 1459 bits (3776), Expect = 0.0
Identities = 733/733 (100%), Positives = 733/733 (100%)
Query: 1 MLSFFRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDSKSIITCRVSLLDGTDVSVDLP 60
MLSFFRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDSKSIITCRVSLLDGTDVSVDLP
Sbjct: 1 MLSFFRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDSKSIITCRVSLLDGTDVSVDLP 60
Query: 61 KKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRV 120
KKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRV
Sbjct: 61 KKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRV 120
Query: 121 KFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAAYNLQAELGDYDLAEHS 180
KFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAAYNLQAELGDYDLAEHS
Sbjct: 121 KFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAAYNLQAELGDYDLAEHS 180
Query: 181 PELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKAR 240
PELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKAR
Sbjct: 181 PELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKAR 240
Query: 241 DGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFV 300
DGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFV
Sbjct: 241 DGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFV 300
Query: 301 FRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNK 360
FRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNK
Sbjct: 301 FRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNK 360
Query: 361 ARRSTSFERRPSKRYSRRTLQMKACATKPEELSVHNNVSTQSNGSQQAWGMRSALPVSPS 420
ARRSTSFERRPSKRYSRRTLQMKACATKPEELSVHNNVSTQSNGSQQAWGMRSALPVSPS
Sbjct: 361 ARRSTSFERRPSKRYSRRTLQMKACATKPEELSVHNNVSTQSNGSQQAWGMRSALPVSPS 420
Query: 421 ISSAPVPVEIENLPQSPGTDQHDRKCIPLNIDLLNSPDLLEATIGDVIGASDTMETSQAL 480
ISSAPVPVEIENLPQSPGTDQHDRKCIPLNIDLLNSPDLLEATIGDVIGASDTMETSQAL
Sbjct: 421 ISSAPVPVEIENLPQSPGTDQHDRKCIPLNIDLLNSPDLLEATIGDVIGASDTMETSQAL 480
Query: 481 NDVNVATRLPGLGEPEVEYETLKDTSEKLKQLEMENSPLLSPRSNIDVNINSQEEVVKLT 540
NDVNVATRLPGLGEPEVEYETLKDTSEKLKQLEMENSPLLSPRSNIDVNINSQEEVVKLT
Sbjct: 481 NDVNVATRLPGLGEPEVEYETLKDTSEKLKQLEMENSPLLSPRSNIDVNINSQEEVVKLT 540
Query: 541 EKCLNNVIESPGLNVMRVPPDFKSNILKAQVEAVHKVTKEDSLLSHKNANVQDAATNSAV 600
EKCLNNVIESPGLNVMRVPPDFKSNILKAQVEAVHKVTKEDSLLSHKNANVQDAATNSAV
Sbjct: 541 EKCLNNVIESPGLNVMRVPPDFKSNILKAQVEAVHKVTKEDSLLSHKNANVQDAATNSAV 600
Query: 601 LNENNVPLPKESLETLMLITPADSGSVLKEATDELDALLASLTENLIDHTVAPQVSSTSM 660
LNENNVPLPKESLETLMLITPADSGSVLKEATDELDALLASLTENLIDHTVAPQVSSTSM
Sbjct: 601 LNENNVPLPKESLETLMLITPADSGSVLKEATDELDALLASLTENLIDHTVAPQVSSTSM 660
Query: 661 ITPRWIVPQSGAMSNGLAGCEMLLTGKEGHGNKDGISLISPPAPFLVDAVTSSGPILAEE 720
ITPRWIVPQSGAMSNGLAGCEMLLTGKEGHGNKDGISLISPPAPFLVDAVTSSGPILAEE
Sbjct: 661 ITPRWIVPQSGAMSNGLAGCEMLLTGKEGHGNKDGISLISPPAPFLVDAVTSSGPILAEE 720
Query: 721 AVLKQKCLLTTEL 733
AVLKQKCLLTTEL
Sbjct: 721 AVLKQKCLLTTEL 733
>gi|110624790 erythrocyte membrane protein band 4.1 like 4B isoform
2 [Homo sapiens]
Length = 900
Score = 580 bits (1495), Expect = e-165
Identities = 341/675 (50%), Positives = 422/675 (62%), Gaps = 98/675 (14%)
Query: 1 MLSFFRRTLGRRSMRKHAEKERLREAQR-------------------------------- 28
ML F RRT GRRSM+++A R A
Sbjct: 1 MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFP 60
Query: 29 ----------AATHIPAAGDSKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDL 78
AA HI AAG +K+ + CRV LLDGT+VSVDLPK AKGQ+LFDQI+YHLDL
Sbjct: 61 AGGGPLLTGGAAVHISAAGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDL 120
Query: 79 IESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYL 138
+E+DYFGL+F+DSAQVAHWLD K IKKQ+KIG Y LH RVK+YSSEPNNLREE TRYL
Sbjct: 121 VETDYFGLQFLDSAQVAHWLDHAKPIKKQMKIGPAYALHFRVKYYSSEPNNLREEFTRYL 180
Query: 139 FVLQLKQDILSGKLDCPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEME 198
FVLQL+ DILSGKL CP++TAV+LAA LQAELG+ +L EH+PELVSEFRF+P QTE ME
Sbjct: 181 FVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAME 240
Query: 199 LAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFE 258
IF++WKE RG++PAQAE +YLNKAKWLEMYGVDMHVV+ RDG +YSLGLTPTG+L+FE
Sbjct: 241 FDIFQRWKECRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFE 300
Query: 259 GDTKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVE 318
G KIGLFFWPKIT++DFKK+KLTLVVVEDDDQG+EQEHTFVFRLD + CKHLWKCAVE
Sbjct: 301 GANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVE 360
Query: 319 HHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRY-SR 377
HHAFFRLR P S+RS FIRLGSRFR+SG+TEYQ T ++ RR+++FER+PSKRY SR
Sbjct: 361 HHAFFRLRTPGNSKSNRSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSR 420
Query: 378 RTLQMKA---------CA-TKPEELSVHNNVSTQSNGSQQAWGMRSALPVSPSISSAPVP 427
R KA C+ T PE + + SQ W P SP++S P+P
Sbjct: 421 RHSTFKASNPVIAAQLCSKTNPEVHNYQPQYHPNIHPSQPRWH-----PHSPNVSY-PLP 474
Query: 428 VEIENLPQSPGTDQHDRKCIPLNIDLLNSPDLLEATIGDVIGASDTMETSQALNDVNVAT 487
SP DR +P I+ L A G Q ++ +++
Sbjct: 475 --------SPVLSSSDR--LPFGIEENGGTPFLTAASGRHHHQHQHQHQHQHHSNYSLSL 524
Query: 488 RLPG----LGEPEVEYETL-----------KDTSEKLKQLEMENSPLLSPRSNIDVNINS 532
L L P ++L + + LK+LE+E P + +NIN
Sbjct: 525 TLENKEGPLRSPNSSSKSLTKLSPGTPALFSEAAAHLKKLELETVKAAGPWPPLHININK 584
Query: 533 QEEVVKLTEKCLNN-VIESPGLNVMRVPPDFKSNILKAQVEAVHKVT----KEDS--LLS 585
EE K++EK L ++ SP V K NILKAQ+E +V KE+S +
Sbjct: 585 AEEK-KVSEKTLQTPLLPSP------VADHVKCNILKAQLENASRVNIQGGKEESPFVNI 637
Query: 586 HKNANVQDAATNSAV 600
+K +++QDA+ S +
Sbjct: 638 NKKSSLQDASVRSPI 652
>gi|110624794 erythrocyte membrane protein band 4.1 like 4B isoform
1 [Homo sapiens]
Length = 518
Score = 553 bits (1426), Expect = e-157
Identities = 289/474 (60%), Positives = 340/474 (71%), Gaps = 58/474 (12%)
Query: 1 MLSFFRRTLGRRSMRKHAEKERLREAQR-------------------------------- 28
ML F RRT GRRSM+++A R A
Sbjct: 1 MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFP 60
Query: 29 ----------AATHIPAAGDSKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDL 78
AA HI AAG +K+ + CRV LLDGT+VSVDLPK AKGQ+LFDQI+YHLDL
Sbjct: 61 AGGGPLLTGGAAVHISAAGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDL 120
Query: 79 IESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYL 138
+E+DYFGL+F+DSAQVAHWLD K IKKQ+KIG Y LH RVK+YSSEPNNLREE TRYL
Sbjct: 121 VETDYFGLQFLDSAQVAHWLDHAKPIKKQMKIGPAYALHFRVKYYSSEPNNLREEFTRYL 180
Query: 139 FVLQLKQDILSGKLDCPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEME 198
FVLQL+ DILSGKL CP++TAV+LAA LQAELG+ +L EH+PELVSEFRF+P QTE ME
Sbjct: 181 FVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAME 240
Query: 199 LAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFE 258
IF++WKE RG++PAQAE +YLNKAKWLEMYGVDMHVV+ RDG +YSLGLTPTG+L+FE
Sbjct: 241 FDIFQRWKECRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFE 300
Query: 259 GDTKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVE 318
G KIGLFFWPKIT++DFKK+KLTLVVVEDDDQG+EQEHTFVFRLD + CKHLWKCAVE
Sbjct: 301 GANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVE 360
Query: 319 HHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRY-SR 377
HHAFFRLR P S+RS FIRLGSRFR+SG+TEYQ T ++ RR+++FER+PSKRY SR
Sbjct: 361 HHAFFRLRTPGNSKSNRSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSR 420
Query: 378 RTLQMKA---------CA-TKPEELSVHNNVSTQSNGSQQAWGMRSALPVSPSI 421
R KA C+ T PE + + SQ W P SP++
Sbjct: 421 RHSTFKASNPVIAAQLCSKTNPEVHNYQPQYHPNIHPSQPRWH-----PHSPNV 469
>gi|207113199 erythrocyte membrane protein band 4.1-like 2 isoform b
[Homo sapiens]
Length = 673
Score = 292 bits (747), Expect = 9e-79
Identities = 153/337 (45%), Positives = 215/337 (63%), Gaps = 7/337 (2%)
Query: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTK 102
+ C+V+LLDGT+ S DL K AKGQ LFD++ HL+L+E DYFGL F +S + +WLD K
Sbjct: 218 VQCKVTLLDGTEYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKNWLDPAK 277
Query: 103 SIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQL 162
IK+Q++ P+ VKFY +P+ L E++TRY LQL+QDI SG+L C F T L
Sbjct: 278 EIKRQLR-NLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALL 336
Query: 163 AAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLN 222
+Y LQAELGDYD EH +SEF+F P QT+E+E + E K +RG +PAQA++ +L
Sbjct: 337 GSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKELEEKVAELHKTHRGLSPAQADSQFLE 396
Query: 223 KAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLT 282
AK L MYGVD+H K +G D LG+ G+L+++ +I F WPKI ++ +K++
Sbjct: 397 NAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFY 456
Query: 283 LVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLG 342
+ V + ++ E T F+L + +A K LWK VEHH F+RL P Q ++ F+ LG
Sbjct: 457 IKV--RPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPP--KAKFLTLG 512
Query: 343 SRFRYSGKTEYQTTKTNKA--RRSTSFERRPSKRYSR 377
S+FRYSG+T+ QT + + R + FER SKR SR
Sbjct: 513 SKFRYSGRTQAQTRQASTLIDRPAPHFERTSSKRVSR 549
>gi|207113195 erythrocyte membrane protein band 4.1-like 2 isoform b
[Homo sapiens]
Length = 673
Score = 292 bits (747), Expect = 9e-79
Identities = 153/337 (45%), Positives = 215/337 (63%), Gaps = 7/337 (2%)
Query: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTK 102
+ C+V+LLDGT+ S DL K AKGQ LFD++ HL+L+E DYFGL F +S + +WLD K
Sbjct: 218 VQCKVTLLDGTEYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKNWLDPAK 277
Query: 103 SIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQL 162
IK+Q++ P+ VKFY +P+ L E++TRY LQL+QDI SG+L C F T L
Sbjct: 278 EIKRQLR-NLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALL 336
Query: 163 AAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLN 222
+Y LQAELGDYD EH +SEF+F P QT+E+E + E K +RG +PAQA++ +L
Sbjct: 337 GSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKELEEKVAELHKTHRGLSPAQADSQFLE 396
Query: 223 KAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLT 282
AK L MYGVD+H K +G D LG+ G+L+++ +I F WPKI ++ +K++
Sbjct: 397 NAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFY 456
Query: 283 LVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLG 342
+ V + ++ E T F+L + +A K LWK VEHH F+RL P Q ++ F+ LG
Sbjct: 457 IKV--RPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPP--KAKFLTLG 512
Query: 343 SRFRYSGKTEYQTTKTNKA--RRSTSFERRPSKRYSR 377
S+FRYSG+T+ QT + + R + FER SKR SR
Sbjct: 513 SKFRYSGRTQAQTRQASTLIDRPAPHFERTSSKRVSR 549
>gi|4503579 erythrocyte membrane protein band 4.1-like 2 isoform a
[Homo sapiens]
Length = 1005
Score = 292 bits (747), Expect = 9e-79
Identities = 153/337 (45%), Positives = 215/337 (63%), Gaps = 7/337 (2%)
Query: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTK 102
+ C+V+LLDGT+ S DL K AKGQ LFD++ HL+L+E DYFGL F +S + +WLD K
Sbjct: 218 VQCKVTLLDGTEYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKNWLDPAK 277
Query: 103 SIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQL 162
IK+Q++ P+ VKFY +P+ L E++TRY LQL+QDI SG+L C F T L
Sbjct: 278 EIKRQLR-NLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALL 336
Query: 163 AAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLN 222
+Y LQAELGDYD EH +SEF+F P QT+E+E + E K +RG +PAQA++ +L
Sbjct: 337 GSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKELEEKVAELHKTHRGLSPAQADSQFLE 396
Query: 223 KAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLT 282
AK L MYGVD+H K +G D LG+ G+L+++ +I F WPKI ++ +K++
Sbjct: 397 NAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFY 456
Query: 283 LVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLG 342
+ V + ++ E T F+L + +A K LWK VEHH F+RL P Q ++ F+ LG
Sbjct: 457 IKV--RPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPP--KAKFLTLG 512
Query: 343 SRFRYSGKTEYQTTKTNKA--RRSTSFERRPSKRYSR 377
S+FRYSG+T+ QT + + R + FER SKR SR
Sbjct: 513 SKFRYSGRTQAQTRQASTLIDRPAPHFERTSSKRVSR 549
>gi|87042275 erythrocyte protein band 4.1-like 4 [Homo sapiens]
Length = 686
Score = 288 bits (736), Expect = 2e-77
Identities = 163/412 (39%), Positives = 236/412 (57%), Gaps = 27/412 (6%)
Query: 45 CRVSLLDGTDVSVD-----LPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLD 99
C V LLD + +++ + K KG + D + +H++L+E DYFGLR+ D + +WLD
Sbjct: 13 CEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLD 72
Query: 100 GTKSI---KKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPF 156
K++ K+ + G PY L+ +KFY+ +P L+EE+TRY F LQ+KQD+L G+L CP
Sbjct: 73 PAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCPV 132
Query: 157 DTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQA 216
+TA QL AY +Q+ELGDYD +H+ VSE+RFVP Q EE+E AI K GQ P++A
Sbjct: 133 NTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIPSEA 192
Query: 217 ETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDF 276
E NYL AK LEMYGVD+H V + ++Y LGLTP GV+V++ ++G +FWP+IT++ F
Sbjct: 193 ELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVHF 252
Query: 277 KKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHR- 335
K+ + L V+ D E +F F ACKHLWKC+VEHH FFR+ S R
Sbjct: 253 KETQFELRVLGKDC----NETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSLSRK 308
Query: 336 -SGFIRLGSRFRYSGKTEYQTTK---TNKARRSTSFERRPSKRYSRRTLQMKACATKP-E 390
S F + + RYSG+T Q ++ R + R SK Y +R Q T+P E
Sbjct: 309 LSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQ-----TQPAE 363
Query: 391 ELSVHNNVSTQSNGSQQAWGMRSALPVSPSISSAPVPVEIENLPQSPGTDQH 442
S+ + NG + + ++PS + + EN P + + H
Sbjct: 364 SNSISRITANMENGENEG----TIKIIAPSPVKSFKKAKNENSPDTQRSKSH 411
>gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform a
[Homo sapiens]
Length = 881
Score = 282 bits (721), Expect = 9e-76
Identities = 167/443 (37%), Positives = 248/443 (55%), Gaps = 19/443 (4%)
Query: 18 AEKERLREAQRAATHIPAAGDSKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLD 77
+E+ +AQ++ I A KS I CRV+LLD ++ ++ K +GQ LFD + HL+
Sbjct: 75 SERTTPSKAQKSPQKI--AKKYKSAI-CRVTLLDASEYECEVEKHGRGQVLFDLVCEHLN 131
Query: 78 LIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRY 137
L+E DYFGL F D+ +WLD +K IKKQ++ SP+ VKFY +P L E++TRY
Sbjct: 132 LLEKDYFGLTFCDADSQKNWLDPSKEIKKQIR-SSPWNFAFTVKFYPPDPAQLTEDITRY 190
Query: 138 LFVLQLKQDILSGKLDCPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEM 197
LQL+ DI++G+L C F T L +Y +QAELGDYD EH VSE RF P QT E+
Sbjct: 191 YLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTREL 250
Query: 198 ELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVF 257
E I E K YRG TP +AE ++L AK L MYGVD+H K +G D LG+ G+L++
Sbjct: 251 EERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIY 310
Query: 258 EGDTKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAV 317
+I F WPKI ++ +K++ + + + ++ E T F+L + ++ K LWK +
Sbjct: 311 RDRLRINRFAWPKILKISYKRSNFYIKI--RPGEYEQFESTIGFKLPNHRSAKRLWKVCI 368
Query: 318 EHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKA--RRSTSFERRPSKRY 375
EHH FFRL P GF+ +GS+FRYSG+T+ QT + + R + FER SKRY
Sbjct: 369 EHHTFFRLVSP---EPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRY 425
Query: 376 SRRTLQMKACATKPEELSVHNNVSTQSNGSQ---QAWGMRSALPVSPSISSAPVPVEIEN 432
+ A ++P +S +++ + ++ G RS P +I+
Sbjct: 426 TMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRS----EAEEGEVRTPTKIKE 481
Query: 433 L-PQSPGTDQHDRKCIPLNIDLL 454
L P+ T +H ++ + D+L
Sbjct: 482 LKPEQETTPRHKQEFLDKPEDVL 504
>gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform b
[Homo sapiens]
Length = 779
Score = 280 bits (715), Expect = 4e-75
Identities = 156/382 (40%), Positives = 226/382 (59%), Gaps = 11/382 (2%)
Query: 18 AEKERLREAQRAATHIPAAGDSKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLD 77
+E+ +AQ++ I A KS I CRV+LLD ++ ++ K +GQ LFD + HL+
Sbjct: 13 SERTTPSKAQKSPQKI--AKKYKSAI-CRVTLLDASEYECEVEKHGRGQVLFDLVCEHLN 69
Query: 78 LIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRY 137
L+E DYFGL F D+ +WLD +K IKKQ++ SP+ VKFY +P L E++TRY
Sbjct: 70 LLEKDYFGLTFCDADSQKNWLDPSKEIKKQIR-SSPWNFAFTVKFYPPDPAQLTEDITRY 128
Query: 138 LFVLQLKQDILSGKLDCPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEM 197
LQL+ DI++G+L C F T L +Y +QAELGDYD EH VSE RF P QT E+
Sbjct: 129 YLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTREL 188
Query: 198 ELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVF 257
E I E K YRG TP +AE ++L AK L MYGVD+H K +G D LG+ G+L++
Sbjct: 189 EERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIY 248
Query: 258 EGDTKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAV 317
+I F WPKI ++ +K++ + + + ++ E T F+L + ++ K LWK +
Sbjct: 249 RDRLRINRFAWPKILKISYKRSNFYIKI--RPGEYEQFESTIGFKLPNHRSAKRLWKVCI 306
Query: 318 EHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKA--RRSTSFERRPSKRY 375
EHH FFRL P GF+ +GS+FRYSG+T+ QT + + R + FER SKRY
Sbjct: 307 EHHTFFRLVSP---EPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRY 363
Query: 376 SRRTLQMKACATKPEELSVHNN 397
+ A ++P +S +++
Sbjct: 364 TMSRSLDGAEFSRPASVSENHD 385
>gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo
sapiens]
Length = 1087
Score = 278 bits (712), Expect = 1e-74
Identities = 143/334 (42%), Positives = 210/334 (62%), Gaps = 8/334 (2%)
Query: 45 CRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSI 104
C+V LLDG++ + D+ K+++GQ LFD++ HL+L+E DYFGL + D+ +WLD K I
Sbjct: 112 CKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEI 171
Query: 105 KKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAA 164
KKQV+ G+ + VKFY +P L E++TRY LQL+ DI+SG+L C F T L +
Sbjct: 172 KKQVRSGA-WHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGS 230
Query: 165 YNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKA 224
Y +Q+ELGDYD E + +SEFRF P T+E+E + E K +RG TPA+AE ++L A
Sbjct: 231 YTVQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENA 290
Query: 225 KWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLTLV 284
K L MYGVD+H K +G + LG+ +G+L++ +I F WPK+ ++ +K+N +
Sbjct: 291 KKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIK 350
Query: 285 VVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSR 344
+ + ++ E T F+L + +A K LWK VEHH FFRL P + F+ LGS+
Sbjct: 351 I--RPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLP---EAPPKKFLTLGSK 405
Query: 345 FRYSGKTEYQTTKTNKA--RRSTSFERRPSKRYS 376
FRYSG+T+ QT + + R + FER SKRY+
Sbjct: 406 FRYSGRTQAQTRRASALIDRPAPYFERSSSKRYT 439
>gi|42716291 erythrocyte membrane protein band 4.1 (elliptocytosis
1, RH-linked) isoform 2 [Homo sapiens]
Length = 641
Score = 274 bits (701), Expect = 2e-73
Identities = 146/335 (43%), Positives = 204/335 (60%), Gaps = 7/335 (2%)
Query: 45 CRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSI 104
C+VSLLD T + K AKGQ+L ++ HL+L+E DYFGL D+A WLD K I
Sbjct: 3 CKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEI 62
Query: 105 KKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAA 164
KKQV+ G P+ VKFY +P L E++TRY LQL+QDI++G+L C F T L +
Sbjct: 63 KKQVR-GVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGS 121
Query: 165 YNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKA 224
Y +Q+ELGDYD H + VS+F+ P QT+E+E + E K YR TPAQA+ +L A
Sbjct: 122 YTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENA 181
Query: 225 KWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLTLV 284
K L MYGVD+H K +G D LG+ +G+LV++ +I F WPK+ ++ +K++ +
Sbjct: 182 KKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIK 241
Query: 285 VVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSR 344
+ + + + E T F+L +A K LWK VEHH FFRL + +S F+ LGS+
Sbjct: 242 IRPGEQE--QYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTS--TDTIPKSKFLALGSK 297
Query: 345 FRYSGKTEYQTTKTNKA--RRSTSFERRPSKRYSR 377
FRYSG+T+ QT + + R + FER SKR SR
Sbjct: 298 FRYSGRTQAQTRQASALIDRPAPHFERTASKRASR 332
>gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis 1,
RH-linked) isoform 3 [Homo sapiens]
Length = 588
Score = 274 bits (701), Expect = 2e-73
Identities = 146/335 (43%), Positives = 204/335 (60%), Gaps = 7/335 (2%)
Query: 45 CRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSI 104
C+VSLLD T + K AKGQ+L ++ HL+L+E DYFGL D+A WLD K I
Sbjct: 3 CKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEI 62
Query: 105 KKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAA 164
KKQV+ G P+ VKFY +P L E++TRY LQL+QDI++G+L C F T L +
Sbjct: 63 KKQVR-GVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGS 121
Query: 165 YNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKA 224
Y +Q+ELGDYD H + VS+F+ P QT+E+E + E K YR TPAQA+ +L A
Sbjct: 122 YTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENA 181
Query: 225 KWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLTLV 284
K L MYGVD+H K +G D LG+ +G+LV++ +I F WPK+ ++ +K++ +
Sbjct: 182 KKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIK 241
Query: 285 VVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSR 344
+ + + + E T F+L +A K LWK VEHH FFRL + +S F+ LGS+
Sbjct: 242 IRPGEQE--QYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTS--TDTIPKSKFLALGSK 297
Query: 345 FRYSGKTEYQTTKTNKA--RRSTSFERRPSKRYSR 377
FRYSG+T+ QT + + R + FER SKR SR
Sbjct: 298 FRYSGRTQAQTRQASALIDRPAPHFERTASKRASR 332
>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
sapiens]
Length = 926
Score = 269 bits (687), Expect = 8e-72
Identities = 138/342 (40%), Positives = 214/342 (62%), Gaps = 6/342 (1%)
Query: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMD-SAQVAHWLDGT 101
+ C + LLD T + + K +GQ L D + HLDL E DYFGL+ D S WLD
Sbjct: 29 VVCNILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADDSTDNPRWLDPN 88
Query: 102 KSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQ 161
K I+KQ+K GSPY L+ RVKF+ S+PN L+EE TRY + LQ+KQDIL+G+L CP +TA
Sbjct: 89 KPIRKQLKRGSPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLPCPSNTAAL 148
Query: 162 LAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYL 221
LA++ +Q+ELGDYD +E+ +S++ F+P Q ++ E I + +++ G +PA+AE NYL
Sbjct: 149 LASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQDFEKEIAKLHQQHIGLSPAEAEFNYL 208
Query: 222 NKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKL 281
N A+ LE+YGV+ H + + N+ +G+ G+L+++ ++ F W KI ++ FK +
Sbjct: 209 NTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKNRVRMNTFPWLKIVKISFKCKQF 268
Query: 282 TLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPV-QKSSHRSGFIR 340
+ + ++ + +E F + + +ACK+LWK VEHH FFRL P+ + + + +
Sbjct: 269 FIQLRKELHESRET--LLGFNMVNYRACKNLWKACVEHHTFFRLDRPLPPQKNFFAHYFT 326
Query: 341 LGSRFRYSGKTEYQTTK--TNKARRSTSFERRPSKRYSRRTL 380
LGS+FRY G+TE Q+ + KA + F R PSK +R+ +
Sbjct: 327 LGSKFRYCGRTEVQSVQYGKEKANKDRVFARSPSKPLARKLM 368
>gi|94721308 FERM domain containing 5 isoform 2 [Homo sapiens]
Length = 570
Score = 256 bits (654), Expect = 5e-68
Identities = 140/355 (39%), Positives = 210/355 (59%), Gaps = 14/355 (3%)
Query: 36 AGDSKSI---ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSA 92
+G S+S+ +C V LLD ++ + + + AKGQ LFD + +HL+L+E DYFG+RF+D
Sbjct: 7 SGSSRSLEREYSCTVRLLDDSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIRFVDPD 66
Query: 93 QVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKL 152
+ HWL+ TKS+ KQ++ P+ + RVKFY ++P L+EE+TRYL LQ+K+D+ G+L
Sbjct: 67 KQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRL 126
Query: 153 DCPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWK-EYRGQ 211
C A LAAY LQAE+GDYD +H S+F+F P +E++E I E K E GQ
Sbjct: 127 LCKTSDAALLAAYILQAEIGDYDSGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQ 186
Query: 212 TPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKI 271
TPA +E N+L KA+ LE YGVD H K GN L TP G +V +G+ ++ W ++
Sbjct: 187 TPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKWNEV 246
Query: 272 TRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQ- 330
T+L F+ L V Q +E++ + P+ACKHLWKC +E+ AF++L Q
Sbjct: 247 TKLKFEGKTFYLYV----SQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQV 302
Query: 331 KSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKAC 385
++ S GSRFRYSG+ + ++ S +R P + + + ++C
Sbjct: 303 RTVSSSNLFFKGSRFRYSGRVAKEVMES-----SAKIKREPPEIHRAGMVPSRSC 352
>gi|117500790 FERM domain containing 3 [Homo sapiens]
Length = 597
Score = 255 bits (652), Expect = 9e-68
Identities = 163/439 (37%), Positives = 229/439 (52%), Gaps = 29/439 (6%)
Query: 45 CRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSI 104
C + LLD +++S + ++ KGQ L D I + L+E DYFG+R++D + HWL+ KSI
Sbjct: 34 CTIRLLDDSEISCHIQRETKGQFLIDHICNYYSLLEKDYFGIRYVDPEKQRHWLEPNKSI 93
Query: 105 KKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAA 164
KQ+K PY + RVKFY EP ++EELTRYL LQ+K+DI G+L C F A L A
Sbjct: 94 FKQMKTHPPYTMCFRVKFYPHEPLKIKEELTRYLLYLQIKRDIFHGRLLCSFSDAAYLGA 153
Query: 165 YNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWK-EYRGQTPAQAETNYLNK 223
+QAELGDYD EH +SEF P Q++++E I E K E RGQ+P AE N L K
Sbjct: 154 CIVQAELGDYDPDEHPENYISEFEIFPKQSQKLERKIVEIHKNELRGQSPPVAEFNLLLK 213
Query: 224 AKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLTL 283
A LE YGVD H K G LG T G +VF+G+ +I L WP + +L F+ +
Sbjct: 214 AHTLETYGVDPHPCKDSTGTTTFLGFTAAGFVVFQGNKRIHLIKWPDVCKLKFEGKTFYV 273
Query: 284 VVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQ-KSSHRSGFIRLG 342
+ + KE++ F P ACKHLWKC VE+ AF++ Q K+ S G
Sbjct: 274 IGTQ-----KEKKAMLAFHTSTPAACKHLWKCGVENQAFYKYAKSSQIKTVSSSKIFFKG 328
Query: 343 SRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKACATKPEELSVHNN----- 397
SRFRYSGK + + S+ +R P + + Q ++ + ++L ++
Sbjct: 329 SRFRYSGKVAKEVVEA-----SSKIQREPPEVHRANITQSRSSHSLNKQLIINMEPLQPL 383
Query: 398 -VSTQSNGSQQAWGMRSALP-----VSPSISSAPVPVEIENLPQSPGTDQHDR-KCIPLN 450
S + G LP +P ISS+PV E + P +++ D+ K PL
Sbjct: 384 LPSPSEQEEELPLGEGVPLPKEENISAPLISSSPVKAAREY--EDPPSEEEDKIKEEPLT 441
Query: 451 IDLL---NSPDLLEATIGD 466
I L S LL + D
Sbjct: 442 ISELVYNPSASLLPTPVDD 460
>gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosis
1, RH-linked) isoform 1 [Homo sapiens]
Length = 775
Score = 230 bits (587), Expect = 3e-60
Identities = 123/286 (43%), Positives = 173/286 (60%), Gaps = 7/286 (2%)
Query: 94 VAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLD 153
V WLD K IKKQV+ G P+ VKFY +P L E++TRY LQL+QDI++G+L
Sbjct: 226 VETWLDSAKEIKKQVR-GVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLP 284
Query: 154 CPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTP 213
C F T L +Y +Q+ELGDYD H + VS+F+ P QT+E+E + E K YR TP
Sbjct: 285 CSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTP 344
Query: 214 AQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITR 273
AQA+ +L AK L MYGVD+H K +G D LG+ +G+LV++ +I F WPK+ +
Sbjct: 345 AQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLK 404
Query: 274 LDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSS 333
+ +K++ + + + + + E T F+L +A K LWK VEHH FFRL +
Sbjct: 405 ISYKRSSFFIKIRPGEQE--QYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTS--TDTI 460
Query: 334 HRSGFIRLGSRFRYSGKTEYQTTKTNKA--RRSTSFERRPSKRYSR 377
+S F+ LGS+FRYSG+T+ QT + + R + FER SKR SR
Sbjct: 461 PKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASR 506
>gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform 1
[Homo sapiens]
Length = 1045
Score = 229 bits (584), Expect = 7e-60
Identities = 139/394 (35%), Positives = 211/394 (53%), Gaps = 9/394 (2%)
Query: 34 PAAGDSKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQ 93
P S +++ ++ +LD T + ++P++A G+ L D + HL+L+E DYFGL F D +
Sbjct: 31 PPPTPSGKLVSIKIQMLDDTQEAFEVPQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKK 90
Query: 94 VAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLD 153
+ WLD K I KQ++ + VKF+ + L+EELTRYLF LQ+KQD+ G+L
Sbjct: 91 ITVWLDLLKPIVKQIRRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLT 150
Query: 154 CPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTP 213
C +A L ++ +Q+E+GD+D A L +++P Q + +E I E + GQTP
Sbjct: 151 CNDTSAALLISHIVQSEIGDFDEALDREHLAKN-KYIP-QQDALEDKIVEFHHNHIGQTP 208
Query: 214 AQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITR 273
A+++ L A+ LEMYG+ +H K R+G +L + TG+LVF+G TKI F W K+ +
Sbjct: 209 AESDFQLLEIARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRK 268
Query: 274 LDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSS 333
L FK+ + L+ + D Q+ T F + CK WK VEHHAFFRL +
Sbjct: 269 LSFKRKRF-LIKLRPDANSAYQD-TLEFLMASRDFCKSFWKICVEHHAFFRLFEEPKPKP 326
Query: 334 HRSGFIRLGSRFRYSGKTEYQTTKTNK--ARRSTSFERRPSKRYSRRTLQMKACATKPE- 390
F R GS FR+SG+T+ Q K + FER+ SK +S R+L + E
Sbjct: 327 KPVLFSR-GSSFRFSGRTQKQVLDYVKEGGHKKVQFERKHSKIHSIRSLASQPTELNSEV 385
Query: 391 -ELSVHNNVSTQSNGSQQAWGMRSALPVSPSISS 423
E S + T G++ G P +S+
Sbjct: 386 LEQSQQSTSLTFGEGAESPGGQSCRRGKEPKVSA 419
>gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo
sapiens]
Length = 1054
Score = 213 bits (541), Expect = 7e-55
Identities = 129/334 (38%), Positives = 186/334 (55%), Gaps = 9/334 (2%)
Query: 46 RVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIK 105
RV LLD T D+ K GQ L Q+ L+L+E DYFG+ F ++ WL+ K I
Sbjct: 47 RVKLLDNTMEIFDIEPKCDGQVLLTQVWKRLNLVECDYFGMEFQNTQSYWIWLEPMKPII 106
Query: 106 KQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAAY 165
+Q++ L L VKF+ +P L+EE TRYLF LQLK+D+L +L C TA L ++
Sbjct: 107 RQIRRPKNVVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCADTTAALLTSH 166
Query: 166 NLQAELGDYDLAEHSPEL-VSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKA 224
LQ+E+GDYD L V+E ++P Q +E I E +++ GQTPA+++ L A
Sbjct: 167 LLQSEIGDYDETLDREHLKVNE--YLPGQQHCLE-KILEFHQKHVGQTPAESDFQVLEIA 223
Query: 225 KWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLTLV 284
+ LEMYG+ H+ R+G L ++ GVLVF+G TKI F W K+ +L FK+ + L+
Sbjct: 224 RKLEMYGIRFHMASDREGTKIQLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRF-LI 282
Query: 285 VVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSR 344
+ + G Q+ T F L CK+ WK VE+H FFRL K ++ F GS
Sbjct: 283 KLHPEVHGPYQD-TLEFLLGSRDECKNFWKICVEYHTFFRLLDQ-PKPKAKAVFFSRGSS 340
Query: 345 FRYSGKTEYQTTK--TNKARRSTSFERRPSKRYS 376
FRYSG+T+ Q + + +ERR SK ++
Sbjct: 341 FRYSGRTQKQLVDYFKDSGMKRIPYERRHSKTHT 374
>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
isoform 2 [Homo sapiens]
Length = 868
Score = 212 bits (539), Expect = 1e-54
Identities = 127/416 (30%), Positives = 216/416 (51%), Gaps = 15/416 (3%)
Query: 39 SKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMD-SAQVAHW 97
++S + C + LDG + + K+ GQ L D + HL + E +YFGL+ D S W
Sbjct: 25 TRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRW 84
Query: 98 LDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFD 157
L+ +K+I+KQ+K G P LH RV+F+ +PN L++E TR+L+ LQLK DI G+L CP +
Sbjct: 85 LEASKAIRKQLKGGFPCTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLN 144
Query: 158 TAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAE 217
+AV LA+Y +Q+ GDY+ + H P +S+ F+P Q E+ + +++ G ++AE
Sbjct: 145 SAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAE 204
Query: 218 TNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFK 277
+ Y+N A+ L+ YGV++H + D +G+ GV V+ + W I ++ FK
Sbjct: 205 SCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFYPWVNILKISFK 264
Query: 278 KNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPV-QKSSHRS 336
+ K + + Q + +EH F + + ++CK+LWK VEHH FF+ + + Q+ + S
Sbjct: 265 RKK--FFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLS 322
Query: 337 GFIRLGS--------RFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRR--TLQMKACA 386
+ +GS R R+ + ++ N A T Y+ + + +
Sbjct: 323 QYWTMGSRNTKKRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDS 382
Query: 387 TKPEELSVHNNVSTQSNGSQQAWGMRSALPVSPSISSAPVPVEIENLPQSPGTDQH 442
+ S H +++N +Q +S+ VSPS S+AP + + Q D H
Sbjct: 383 EVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPS-SNAPGSCSPDGVDQQLLDDFH 437
>gi|223941876 protein tyrosine phosphatase, non-receptor type 3
isoform 1 [Homo sapiens]
Length = 913
Score = 207 bits (526), Expect = 4e-53
Identities = 107/308 (34%), Positives = 178/308 (57%), Gaps = 4/308 (1%)
Query: 39 SKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMD-SAQVAHW 97
++S + C + LDG + + K+ GQ L D + HL + E +YFGL+ D S W
Sbjct: 25 TRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRW 84
Query: 98 LDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFD 157
L+ +K+I+KQ+K G P LH RV+F+ +PN L++E TR+L+ LQLK DI G+L CP +
Sbjct: 85 LEASKAIRKQLKGGFPCTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLN 144
Query: 158 TAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAE 217
+AV LA+Y +Q+ GDY+ + H P +S+ F+P Q E+ + +++ G ++AE
Sbjct: 145 SAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAE 204
Query: 218 TNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFK 277
+ Y+N A+ L+ YGV++H + D +G+ GV V+ + W I ++ FK
Sbjct: 205 SCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFYPWVNILKISFK 264
Query: 278 KNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPV-QKSSHRS 336
+ K + + Q + +EH F + + ++CK+LWK VEHH FF+ + + Q+ + S
Sbjct: 265 RKK--FFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLS 322
Query: 337 GFIRLGSR 344
+ +GSR
Sbjct: 323 QYWTMGSR 330
>gi|34916000 FERM domain containing 7 [Homo sapiens]
Length = 714
Score = 189 bits (480), Expect = 8e-48
Identities = 130/376 (34%), Positives = 198/376 (52%), Gaps = 32/376 (8%)
Query: 46 RVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIK 105
+V LD + + +K+ G+ LF+ HL+L E +YFGL F + WL+ K I
Sbjct: 5 KVQFLDDSQKIFVVDQKSSGKALFNLSCSHLNLAEKEYFGLEFCSHSGNNVWLELLKPIT 64
Query: 106 KQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAAY 165
KQVK VKF+ +P +LREELTRYLF LQ+K+D+ G+L C + + ++
Sbjct: 65 KQVKNPKEIVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSH 124
Query: 166 NLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAK 225
LQ+ELGD+ E + +++ R++P Q + +E I +++ G++PA+++ L+ A+
Sbjct: 125 ILQSELGDFH-EETDRKHLAQTRYLPNQ-DCLEGKIMHFHQKHIGRSPAESDILLLDIAR 182
Query: 226 WLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKL---- 281
L+MYG+ H +G L + GVLV G+TKI F W KI +L FK+
Sbjct: 183 KLDMYGIRPHPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKL 242
Query: 282 ---TLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGF 338
LV+ +D T F + ACK WK VE+HAFFRL KS ++
Sbjct: 243 HANILVLCKD---------TLEFTMASRDACKAFWKTCVEYHAFFRL-SEEPKSKPKTLL 292
Query: 339 IRLGSRFRYSGKTEYQTTKTNKARR--STSFERR--PSKRYSRRTLQMKACATKPEELSV 394
GS FRYSG+T+ Q + + R S FER+ PS+ + R+ C + P+ LS
Sbjct: 293 CSKGSSFRYSGRTQRQLLEYGRKGRLKSLPFERKHYPSQYHERQ------CRSSPDLLS- 345
Query: 395 HNNVSTQSNGSQQAWG 410
+VS Q + A+G
Sbjct: 346 --DVSKQVEDLRLAYG 359
>gi|239754880 PREDICTED: similar to hCG2040198 [Homo sapiens]
Length = 169
Score = 170 bits (431), Expect = 4e-42
Identities = 87/95 (91%), Positives = 89/95 (93%)
Query: 1 MLSFFRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDSKSIITCRVSLLDGTDVSVDLP 60
MLSFFRRTLG RSM KHAEKERLREAQ AATHIPA GDS+SIITC+VSLLDGTDVSVDLP
Sbjct: 72 MLSFFRRTLGSRSMGKHAEKERLREAQCAATHIPAPGDSRSIITCQVSLLDGTDVSVDLP 131
Query: 61 KKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVA 95
KKAKGQELFDQIMYHLDLIES YF LRFMDSAQVA
Sbjct: 132 KKAKGQELFDQIMYHLDLIESGYFDLRFMDSAQVA 166
>gi|239749418 PREDICTED: similar to hCG2040198 [Homo sapiens]
Length = 169
Score = 170 bits (431), Expect = 4e-42
Identities = 87/95 (91%), Positives = 89/95 (93%)
Query: 1 MLSFFRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDSKSIITCRVSLLDGTDVSVDLP 60
MLSFFRRTLG RSM KHAEKERLREAQ AATHIPA GDS+SIITC+VSLLDGTDVSVDLP
Sbjct: 72 MLSFFRRTLGSRSMGKHAEKERLREAQCAATHIPAPGDSRSIITCQVSLLDGTDVSVDLP 131
Query: 61 KKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVA 95
KKAKGQELFDQIMYHLDLIES YF LRFMDSAQVA
Sbjct: 132 KKAKGQELFDQIMYHLDLIESGYFDLRFMDSAQVA 166
>gi|239743554 PREDICTED: similar to hCG2040198 [Homo sapiens]
Length = 169
Score = 170 bits (431), Expect = 4e-42
Identities = 87/95 (91%), Positives = 89/95 (93%)
Query: 1 MLSFFRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDSKSIITCRVSLLDGTDVSVDLP 60
MLSFFRRTLG RSM KHAEKERLREAQ AATHIPA GDS+SIITC+VSLLDGTDVSVDLP
Sbjct: 72 MLSFFRRTLGSRSMGKHAEKERLREAQCAATHIPAPGDSRSIITCQVSLLDGTDVSVDLP 131
Query: 61 KKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVA 95
KKAKGQELFDQIMYHLDLIES YF LRFMDSAQVA
Sbjct: 132 KKAKGQELFDQIMYHLDLIESGYFDLRFMDSAQVA 166
>gi|150418005 protein tyrosine phosphatase, non-receptor type 21
[Homo sapiens]
Length = 1174
Score = 139 bits (349), Expect = 1e-32
Identities = 87/296 (29%), Positives = 145/296 (48%), Gaps = 17/296 (5%)
Query: 39 SKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWL 98
SKS + R+ LL+ V L ++ GQE + + L+L E YF L + + W+
Sbjct: 19 SKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELREVTYFSLWYYNKQNQRRWV 78
Query: 99 DGTKSIKKQV-KIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFD 157
D K +KKQ+ K ++ V FY + L++E+TRY + LQLK+DIL G + C +
Sbjct: 79 DLEKPLKKQLDKYALEPTVYFGVVFYVPSVSQLQQEITRYQYYLQLKKDILEGSIPCTLE 138
Query: 158 TAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPI-------QTEEMELAIFEKWKEYRG 210
A+QLA +QA+ GD+D E S + + +F P+ EE + ++YRG
Sbjct: 139 QAIQLAGLAVQADFGDFDQYE-SQDFLQKFALFPVGWLQDEKVLEEATQKVALLHQKYRG 197
Query: 211 QTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFF-WP 269
T AE Y+ + + ++ YG + + K G+D S+G G+ V + + + F W
Sbjct: 198 LTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEGIFVKHKNGRHPVVFRWH 257
Query: 270 KITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRL 325
I + K+ L + +E T F+ + + K++W+ V H F+RL
Sbjct: 258 DIANMSHNKSFFALELA-------NKEETIQFQTEDMETAKYIWRLCVARHKFYRL 306
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 132 bits (333), Expect = 9e-31
Identities = 100/360 (27%), Positives = 169/360 (46%), Gaps = 33/360 (9%)
Query: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTK 102
I RV+ +D ++ + G++LFDQ++ + L E YFGL ++D+ WL K
Sbjct: 5 INVRVTTMDA-ELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDK 63
Query: 103 SIKKQ-VKIGSPYCLHLRVKFYSSE-PNNLREELTRYLFVLQLKQDILSGKLDCPFDTAV 160
+ Q V+ +P R KFY + L +++T+ LF LQ+K+ ILS ++ CP +TAV
Sbjct: 64 KVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAV 123
Query: 161 QLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWK--------EYRGQT 212
L +Y +QA+ GDY+ H +S R +P + + ++W+ E+RG
Sbjct: 124 LLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGML 183
Query: 213 PAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGD----TKIGLFFW 268
A YL A+ LEMYG++ +K + G D LG+ G+ ++E D KIG F W
Sbjct: 184 KDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIG-FPW 242
Query: 269 PKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWK-CAVEHHAFFRLRG 327
+I + F K + ++ ++ FVF + K + + C H + R R
Sbjct: 243 SEIRNISFNDKKFVIKPID------KKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRK 296
Query: 328 P----VQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMK 383
P VQ+ ++ ++ + E Q +T K RR T + + L ++
Sbjct: 297 PDTIEVQQMKAQA------REEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLR 350
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 132 bits (333), Expect = 9e-31
Identities = 100/360 (27%), Positives = 169/360 (46%), Gaps = 33/360 (9%)
Query: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTK 102
I RV+ +D ++ + G++LFDQ++ + L E YFGL ++D+ WL K
Sbjct: 5 INVRVTTMDA-ELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDK 63
Query: 103 SIKKQ-VKIGSPYCLHLRVKFYSSE-PNNLREELTRYLFVLQLKQDILSGKLDCPFDTAV 160
+ Q V+ +P R KFY + L +++T+ LF LQ+K+ ILS ++ CP +TAV
Sbjct: 64 KVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAV 123
Query: 161 QLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWK--------EYRGQT 212
L +Y +QA+ GDY+ H +S R +P + + ++W+ E+RG
Sbjct: 124 LLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGML 183
Query: 213 PAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGD----TKIGLFFW 268
A YL A+ LEMYG++ +K + G D LG+ G+ ++E D KIG F W
Sbjct: 184 KDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIG-FPW 242
Query: 269 PKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWK-CAVEHHAFFRLRG 327
+I + F K + ++ ++ FVF + K + + C H + R R
Sbjct: 243 SEIRNISFNDKKFVIKPID------KKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRK 296
Query: 328 P----VQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMK 383
P VQ+ ++ ++ + E Q +T K RR T + + L ++
Sbjct: 297 PDTIEVQQMKAQA------REEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLR 350
>gi|34328899 protein tyrosine phosphatase, non-receptor type 14
[Homo sapiens]
Length = 1187
Score = 132 bits (333), Expect = 9e-31
Identities = 84/298 (28%), Positives = 151/298 (50%), Gaps = 23/298 (7%)
Query: 39 SKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWL 98
SK+ R+ LLD + L ++ GQE + + L+L E+ YFGL F+ +Q A W+
Sbjct: 17 SKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWV 76
Query: 99 DGTKSIKKQV-KIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFD 157
+ K +KK + K + L V FY + L++E TRY + LQ+K+D+L G+L C D
Sbjct: 77 ELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCTLD 136
Query: 158 TAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQ-------TEEMELAIFEKWKEYRG 210
++LA +QA+ GDY+ + S + + E+ P+ EE+ + ++ K + G
Sbjct: 137 QVIRLAGLAVQADFGDYNQFD-SQDFLREYVLFPMDLALEEAVLEELTQKVAQEHKAHSG 195
Query: 211 QTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIG----LF 266
PA+AE Y+N+ + L+ +G ++ VK GN LG+ G+ V +IG ++
Sbjct: 196 ILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMGIFV---RNRIGRQAVIY 252
Query: 267 FWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFR 324
W + + K+ + + ++ +E T +F D + K++ + H F++
Sbjct: 253 RWNDMGNITHNKSTILVELI-------NKEETALFHTDDIENAKYISRLFATRHKFYK 303
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 132 bits (332), Expect = 1e-30
Identities = 146/614 (23%), Positives = 254/614 (41%), Gaps = 53/614 (8%)
Query: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTK 102
I RV+ +D ++ + G++LFDQ++ + L E +FGL+++DS + WL K
Sbjct: 5 INVRVTTMDA-ELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNK 63
Query: 103 SIKKQ-VKIGSPYCLHLRVKFYSSEPNN-LREELTRYLFVLQLKQDILSGKLDCPFDTAV 160
+ +Q VK +P R KF+ + + L +E+T+ LF LQ+K+ IL+ ++ CP +TAV
Sbjct: 64 KVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAV 123
Query: 161 QLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKW--------KEYRGQT 212
LA+Y +QA+ GDY+ H P ++ R +P + E E+W +E+RG
Sbjct: 124 LLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGML 183
Query: 213 PAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGD----TKIGLFFW 268
+ YL A+ LEMYGV+ +K + G + LG+ G+ ++E D KIG F W
Sbjct: 184 REDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIG-FPW 242
Query: 269 PKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKH-LWKCAVEHHAFFRLRG 327
+I + F K + ++ ++ FVF + K L C H + R R
Sbjct: 243 SEIRNISFNDKKFVIKPID------KKAPDFVFYAPRLRINKRILALCMGNHELYMRRRK 296
Query: 328 PVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKACAT 387
P + K + + K K E KR + +
Sbjct: 297 PDTIEVQQM-------------KAQAREEKHQKQLERAQLENEKKKREIAEKEKERIERE 343
Query: 388 KPEELSVHNNVSTQSNGSQQAWGMRSALPVSPSISSAPVPVEIENLPQSPGTDQHDRKCI 447
K E + + Q+ +Q+ ++ + E E L + + + I
Sbjct: 344 KEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAI 403
Query: 448 PLN-IDLLNSPDLLEATIGDVIGASDTMETSQALNDVNVATRLPGLGEPEVEYETLKDTS 506
D + + + L A + + +E ++ + + E L+ T
Sbjct: 404 AKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEAT---EWQHKAFAAQEDLEKTK 460
Query: 507 EKLKQLEMENSPLLSPRSNIDVNINSQEEVVKLTEKCLNNVIESPGLNVMRVPPDFKSNI 566
E+LK + M P P I N +E + NN S L+ V
Sbjct: 461 EELKTV-MSAPPPPPPPPVIPPTENEHDEHDE------NNAEASAELSNEGVMNHRSEEE 513
Query: 567 LKAQVEAVHKVTKEDSLLSHKNANVQDAA--TNSAVLNENNVPLPKESLETLMLITPADS 624
+ + +V K+ LS + A +D T + VL+ NV ++ +TL I ++
Sbjct: 514 RVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNT 573
Query: 625 GSVLKEATDELDAL 638
K+ DE +A+
Sbjct: 574 ----KQRIDEFEAM 583
>gi|38788243 myosin regulatory light chain interacting protein [Homo
sapiens]
Length = 445
Score = 127 bits (320), Expect = 3e-29
Identities = 83/285 (29%), Positives = 145/285 (50%), Gaps = 16/285 (5%)
Query: 45 CRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSI 104
C V+ D + V++ KA G++ +Q+ L +IE DYFGL+F S + WL+ I
Sbjct: 3 CYVTRPDAVLMEVEVEAKANGEDCLNQVCRRLGIIEVDYFGLQFTGSKGESLWLNLRNRI 62
Query: 105 KKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAA 164
+Q+ +PY L LRVKF+ EP+ + +E TR++F L +K+ +L+G L C + AV+L+A
Sbjct: 63 SQQMDGLAPYRLKLRVKFF-VEPHLILQEQTRHIFFLHIKEALLAGHLLCSPEQAVELSA 121
Query: 165 YNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELA----IFEKWKEYRGQTPAQAETNY 220
Q + GDY+ + +++ + + +E+ A I K KE G + A AE
Sbjct: 122 LLAQTKFGDYN------QNTAKYNYEELCAKELSSATLNSIVAKHKELEGTSQASAEYQV 175
Query: 221 LNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGD-TKIGLFFWPKITRLDFKKN 279
L +E YG++ H V+ +G +G+ P G+ + + D + I +P +
Sbjct: 176 LQIVSAMENYGIEWHSVRDSEGQKLLIGVGPEGISICKDDFSPINRIAYPVVQMATQSGK 235
Query: 280 KLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFR 324
+ L V ++ +F++ +A L++ E HAF+R
Sbjct: 236 NVYLTVTKESG----NSIVLLFKMISTRAASGLYRAITETHAFYR 276
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,152,375
Number of Sequences: 37866
Number of extensions: 1205868
Number of successful extensions: 4043
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 3848
Number of HSP's gapped (non-prelim): 142
length of query: 733
length of database: 18,247,518
effective HSP length: 110
effective length of query: 623
effective length of database: 14,082,258
effective search space: 8773246734
effective search space used: 8773246734
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.