Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 40254808
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40254808 perforin 1 precursor [Homo sapiens]
(555 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|133908621 perforin 1 precursor [Homo sapiens] 1162 0.0
gi|40254808 perforin 1 precursor [Homo sapiens] 1162 0.0
gi|189242612 complement component 6 precursor [Homo sapiens] 87 5e-17
gi|169636415 complement component 6 precursor [Homo sapiens] 87 5e-17
gi|4557389 complement component 8, alpha polypeptide precursor [... 67 6e-11
gi|45580688 complement component 7 precursor [Homo sapiens] 62 2e-09
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo... 47 5e-05
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom... 47 5e-05
gi|4759026 RAS protein activator like 1 [Homo sapiens] 46 1e-04
gi|4502511 complement component 9 precursor [Homo sapiens] 42 0.001
gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Hom... 42 0.002
gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Hom... 42 0.002
gi|103472031 family with sequence similarity 62 (C2 domain conta... 41 0.003
gi|116174754 phospholipase A2, group IVD [Homo sapiens] 40 0.006
gi|122937514 unc-13 homolog C [Homo sapiens] 40 0.006
gi|122937247 unc-13 homolog A [Homo sapiens] 40 0.006
gi|4557391 complement component 8, beta polypeptide preproprotei... 39 0.016
gi|110611226 UNC13 (C. elegans)-like [Homo sapiens] 38 0.021
gi|34740331 otoferlin isoform a [Homo sapiens] 37 0.036
gi|14149680 extended synaptotagmin-like protein 1 [Homo sapiens] 37 0.047
gi|119120884 fer-1-like 6 [Homo sapiens] 36 0.11
gi|27477109 itchy homolog E3 ubiquitin protein ligase [Homo sapi... 34 0.40
gi|227496504 multiple C2 domains, transmembrane 2 isoform 3 [Hom... 33 0.52
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 33 0.89
gi|19718759 myoferlin isoform b [Homo sapiens] 33 0.89
gi|7305053 myoferlin isoform a [Homo sapiens] 33 0.89
gi|148529000 deleted in bladder cancer 1 [Homo sapiens] 32 1.5
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 32 1.5
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 32 1.5
gi|134031945 SCO-spondin [Homo sapiens] 32 2.0
>gi|133908621 perforin 1 precursor [Homo sapiens]
Length = 555
Score = 1162 bits (3007), Expect = 0.0
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MAARLLLLGILLLLLPLPVPAPCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFP 60
MAARLLLLGILLLLLPLPVPAPCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFP
Sbjct: 1 MAARLLLLGILLLLLPLPVPAPCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFP 60
Query: 61 VDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARD 120
VDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARD
Sbjct: 61 VDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARD 120
Query: 121 AARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYS 180
AARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYS
Sbjct: 121 AARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYS 180
Query: 181 FHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALR 240
FHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALR
Sbjct: 181 FHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALR 240
Query: 241 TCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERH 300
TCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERH
Sbjct: 241 TCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERH 300
Query: 301 SEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREAL 360
SEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREAL
Sbjct: 301 SEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREAL 360
Query: 361 RRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVT 420
RRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVT
Sbjct: 361 RRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVT 420
Query: 421 FIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRL 480
FIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRL
Sbjct: 421 FIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRL 480
Query: 481 QVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQ 540
QVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQ
Sbjct: 481 QVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQ 540
Query: 541 MLLGEPPGNRSGAVW 555
MLLGEPPGNRSGAVW
Sbjct: 541 MLLGEPPGNRSGAVW 555
>gi|40254808 perforin 1 precursor [Homo sapiens]
Length = 555
Score = 1162 bits (3007), Expect = 0.0
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MAARLLLLGILLLLLPLPVPAPCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFP 60
MAARLLLLGILLLLLPLPVPAPCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFP
Sbjct: 1 MAARLLLLGILLLLLPLPVPAPCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFP 60
Query: 61 VDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARD 120
VDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARD
Sbjct: 61 VDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARD 120
Query: 121 AARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYS 180
AARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYS
Sbjct: 121 AARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYS 180
Query: 181 FHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALR 240
FHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALR
Sbjct: 181 FHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALR 240
Query: 241 TCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERH 300
TCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERH
Sbjct: 241 TCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERH 300
Query: 301 SEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREAL 360
SEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREAL
Sbjct: 301 SEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREAL 360
Query: 361 RRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVT 420
RRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVT
Sbjct: 361 RRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVT 420
Query: 421 FIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRL 480
FIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRL
Sbjct: 421 FIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRL 480
Query: 481 QVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQ 540
QVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQ
Sbjct: 481 QVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQ 540
Query: 541 MLLGEPPGNRSGAVW 555
MLLGEPPGNRSGAVW
Sbjct: 541 MLLGEPPGNRSGAVW 555
>gi|189242612 complement component 6 precursor [Homo sapiens]
Length = 934
Score = 86.7 bits (213), Expect = 5e-17
Identities = 81/299 (27%), Positives = 126/299 (42%), Gaps = 21/299 (7%)
Query: 150 SHSQAANFAAQKTHQDQYSFSTDTVECRFYSFHVVHTPPLHPD--FKRALGDLPHHFNAS 207
+H+ A A Q +H+ SF + +F LH F +AL LP +N++
Sbjct: 294 NHNSAFKQAIQASHKKDSSFIRIHKVMKVLNF-TTKAKDLHLSDVFLKALNHLPLEYNSA 352
Query: 208 TQPAYLRLISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDCLTVEAQVNIG 267
Y R+ ++GTH+ + LGG L + EL GLT+ E + C+ +E + +
Sbjct: 353 L---YSRIFDDFGTHYFTSGSLGGVYDLLYQFSSEELKNSGLTEEEAKHCVRIETKKRVL 409
Query: 268 IHGSISAEAKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSINDLLFGI-QAGPEQ-- 324
E + C K K SF Q + S + GG L + +G E+
Sbjct: 410 FAKKTKVEHR-CTTNKLSEKHEGSFIQGAEKSISLIRGGRSEYGAALAWEKGSSGLEEKT 468
Query: 325 YSAWVNSLPGSPGLVDYTLEPLHVL---LDSQDPRREALRRALSQYLTDRARWRDCS-RP 380
+S W+ S+ +P ++D+ L P+ L + +R LR+AL +Y A++ C P
Sbjct: 469 FSEWLESVKENPAVIDFELAPIVDLVRNIPCAVTKRNNLRKALQEY---AAKFDPCQCAP 525
Query: 381 CP-PGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVTFIQAWGLWGDWFTATDAY 438
CP GR C CVC T + C +Q + Q WG W W T Y
Sbjct: 526 CPNNGRPTLSGTECLCVCQSG--TYGENCEKQSPDYKSNAVDGQ-WGCWSSWSTCDATY 581
>gi|169636415 complement component 6 precursor [Homo sapiens]
Length = 934
Score = 86.7 bits (213), Expect = 5e-17
Identities = 81/299 (27%), Positives = 126/299 (42%), Gaps = 21/299 (7%)
Query: 150 SHSQAANFAAQKTHQDQYSFSTDTVECRFYSFHVVHTPPLHPD--FKRALGDLPHHFNAS 207
+H+ A A Q +H+ SF + +F LH F +AL LP +N++
Sbjct: 294 NHNSAFKQAIQASHKKDSSFIRIHKVMKVLNF-TTKAKDLHLSDVFLKALNHLPLEYNSA 352
Query: 208 TQPAYLRLISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDCLTVEAQVNIG 267
Y R+ ++GTH+ + LGG L + EL GLT+ E + C+ +E + +
Sbjct: 353 L---YSRIFDDFGTHYFTSGSLGGVYDLLYQFSSEELKNSGLTEEEAKHCVRIETKKRVL 409
Query: 268 IHGSISAEAKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSINDLLFGI-QAGPEQ-- 324
E + C K K SF Q + S + GG L + +G E+
Sbjct: 410 FAKKTKVEHR-CTTNKLSEKHEGSFIQGAEKSISLIRGGRSEYGAALAWEKGSSGLEEKT 468
Query: 325 YSAWVNSLPGSPGLVDYTLEPLHVL---LDSQDPRREALRRALSQYLTDRARWRDCS-RP 380
+S W+ S+ +P ++D+ L P+ L + +R LR+AL +Y A++ C P
Sbjct: 469 FSEWLESVKENPAVIDFELAPIVDLVRNIPCAVTKRNNLRKALQEY---AAKFDPCQCAP 525
Query: 381 CP-PGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVTFIQAWGLWGDWFTATDAY 438
CP GR C CVC T + C +Q + Q WG W W T Y
Sbjct: 526 CPNNGRPTLSGTECLCVCQSG--TYGENCEKQSPDYKSNAVDGQ-WGCWSSWSTCDATY 581
>gi|4557389 complement component 8, alpha polypeptide precursor
[Homo sapiens]
Length = 584
Score = 66.6 bits (161), Expect = 6e-11
Identities = 68/305 (22%), Positives = 121/305 (39%), Gaps = 37/305 (12%)
Query: 145 VSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYSFHVVHTPP---LHPDFKRALGDLP 201
V V SHSQ +F + ++ F + + + H L ++L +LP
Sbjct: 263 VGVGVSHSQDTSFLNELNKYNEKKFIFTRIFTKVQTAHFKMRKDDIMLDEGMLQSLMELP 322
Query: 202 HHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDC---- 257
+N Y + I++YGTH+I + +GG + + ++ G+T ++ C
Sbjct: 323 DQYNYGM---YAKFINDYGTHYITSGSMGGIYEYILVIDKAKMESLGITSRDITTCFGGS 379
Query: 258 LTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSINDLLFG 317
L ++ + I + G +S + H +T R R + V + + G
Sbjct: 380 LGIQYEDKINVGGGLSGD----------HCKKFGGGKTERARKAMAVEDIISRVRGGSSG 429
Query: 318 IQAGPEQ------YSAWVNSLPGSPGLVDYTLEPLHVL-----LDSQDPRREALRRALSQ 366
G Q Y +W SL +P ++D+ ++P+H + L + +R+ LRRAL Q
Sbjct: 430 WSGGLAQNRSTITYRSWGRSLKYNPVVIDFEMQPIHEVLRHTSLGPLEAKRQNLRRALDQ 489
Query: 367 YLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVTFIQAWG 426
YL + R C G C+C C ++ C Q A+ + +W
Sbjct: 490 YLMEFNACR-CGPCFNNGVPILEGTSCRCQCRLGSLGAA-CEQTQTEGAKAD----GSWS 543
Query: 427 LWGDW 431
W W
Sbjct: 544 CWSSW 548
>gi|45580688 complement component 7 precursor [Homo sapiens]
Length = 843
Score = 61.6 bits (148), Expect = 2e-09
Identities = 59/247 (23%), Positives = 96/247 (38%), Gaps = 21/247 (8%)
Query: 193 FKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALRTCELALEGLTDN 252
F + L LP ++ S AY RLI YGTH++++ LGG L + + +L
Sbjct: 276 FWKELSHLPSLYDYS---AYRRLIDQYGTHYLQSGSLGGEYRVLFYVDSEKLKQNDFNSV 332
Query: 253 EVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSIN 312
E + C + G H + + C+E + K + + GG I+
Sbjct: 333 EEKKC------KSSGWHFVVKFSSHGCKELENALKAASGTQNNVLRGEPFIRGGGAGFIS 386
Query: 313 DLLFGIQAGP----EQYSAWVNSLPGSPGLVDYTLEPLHVLLDS---QDPRREALRRALS 365
L + P +YSAW S+ P ++ L PL+ L+ ++ L+ AL
Sbjct: 387 GLSYLELDNPAGNKRRYSAWAESVTNLPQVIKQKLTPLYELVKEVPCASVKKLYLKWALE 446
Query: 366 QYLTDRARWRDC-SRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVTFIQA 424
+YL + + C RPC G + + C+CH T C + +
Sbjct: 447 EYLDE---FDPCHCRPCQNGGLATV-EGTHCLCHCKPYTFGAACEQGVLVGNQAGGVDGG 502
Query: 425 WGLWGDW 431
W W W
Sbjct: 503 WSCWSSW 509
>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
sapiens]
Length = 778
Score = 47.0 bits (110), Expect = 5e-05
Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 12/153 (7%)
Query: 374 WRDCSRPCPPG----RQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQ--LEVTFIQAWGL 427
WR C RP P R + C+ V + R+ L + + +T I+ L
Sbjct: 202 WRTCGRPALPVLGFCRAELQNPYCKNVQFQTQSLRLSDLHRKSHLWRGIVSITLIEGRDL 261
Query: 428 WG-DWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQD 486
D +D YVK G Q+ ++ + NP W + DF + GG + + WD+D
Sbjct: 262 KAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKD 320
Query: 487 SGRDDDLLGTC----DQAPKSGSHEVRCNLNHG 515
+G+ DD +G C + +H++ L G
Sbjct: 321 AGKRDDFIGRCQVDLSALSREQTHKLELQLEEG 353
Score = 40.8 bits (94), Expect = 0.003
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Query: 413 GLAQLEVTFIQAWGLWG-DWFTATDAYVKLFFGGQEL-RTSTVWDNNNPIWSVRLDFGDV 470
G+ QL++T + L D +D YVK GG+E+ R+ + N NP+W + +
Sbjct: 38 GMYQLDITLRRGQSLAARDRGGTSDPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--L 95
Query: 471 LLATGGPLRLQVWDQDSGRDDDLLGT 496
+ PL ++V+D D G DD +G+
Sbjct: 96 VDHLREPLYIKVFDYDFGLQDDFMGS 121
Score = 33.5 bits (75), Expect = 0.52
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 417 LEVTFIQAWGLWGDWFTA-TDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATG 475
L+V I+A GL T +D + + L T TV+ N NP W+ F +
Sbjct: 407 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFN--IKDIH 464
Query: 476 GPLRLQVWDQDSGRDDDLLG 495
L + V+D+D R D LG
Sbjct: 465 SVLEVTVYDEDRDRSADFLG 484
>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
sapiens]
Length = 999
Score = 47.0 bits (110), Expect = 5e-05
Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 12/153 (7%)
Query: 374 WRDCSRPCPPG----RQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQ--LEVTFIQAWGL 427
WR C RP P R + C+ V + R+ L + + +T I+ L
Sbjct: 423 WRTCGRPALPVLGFCRAELQNPYCKNVQFQTQSLRLSDLHRKSHLWRGIVSITLIEGRDL 482
Query: 428 WG-DWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQD 486
D +D YVK G Q+ ++ + NP W + DF + GG + + WD+D
Sbjct: 483 KAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKD 541
Query: 487 SGRDDDLLGTC----DQAPKSGSHEVRCNLNHG 515
+G+ DD +G C + +H++ L G
Sbjct: 542 AGKRDDFIGRCQVDLSALSREQTHKLELQLEEG 574
Score = 40.8 bits (94), Expect = 0.003
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Query: 413 GLAQLEVTFIQAWGLWG-DWFTATDAYVKLFFGGQEL-RTSTVWDNNNPIWSVRLDFGDV 470
G+ QL++T + L D +D YVK GG+E+ R+ + N NP+W + +
Sbjct: 259 GMYQLDITLRRGQSLAARDRGGTSDPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--L 316
Query: 471 LLATGGPLRLQVWDQDSGRDDDLLGT 496
+ PL ++V+D D G DD +G+
Sbjct: 317 VDHLREPLYIKVFDYDFGLQDDFMGS 342
Score = 33.5 bits (75), Expect = 0.52
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 417 LEVTFIQAWGLWGDWFTA-TDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATG 475
L+V I+A GL T +D + + L T TV+ N NP W+ F +
Sbjct: 628 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFN--IKDIH 685
Query: 476 GPLRLQVWDQDSGRDDDLLG 495
L + V+D+D R D LG
Sbjct: 686 SVLEVTVYDEDRDRSADFLG 705
>gi|4759026 RAS protein activator like 1 [Homo sapiens]
Length = 804
Score = 45.8 bits (107), Expect = 1e-04
Identities = 23/69 (33%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 435 TDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQDSGRDDDLL 494
+D + ++F+G Q L TST+ P W L+ ++ A PLR+++WD D +D L
Sbjct: 154 SDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGAPS-PLRVELWDWDMVGKNDFL 212
Query: 495 GTCDQAPKS 503
G + +PK+
Sbjct: 213 GMVEFSPKT 221
>gi|4502511 complement component 9 precursor [Homo sapiens]
Length = 559
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/198 (21%), Positives = 78/198 (39%), Gaps = 14/198 (7%)
Query: 212 YLRLISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDCLTVEAQVNIGIHG- 270
Y + YGTH+ + LGG + L + +G+ +++ CL V++
Sbjct: 335 YFAFLETYGTHYSSSGSLGGLYELIYVLDKASMKRKGVELKDIKRCLGYHLDVSLAFSEI 394
Query: 271 SISAEAKA--CEEKKKKHKMTASFHQTYRERHSEVVGGHHTSI----NDLLFGIQAGPEQ 324
S+ AE C ++ + + + + S + GG LL G
Sbjct: 395 SVGAEFNKDDCVKRGEGRAVNITSENLIDDVVSLIRGGTRKYAFELKEKLLRGTVIDVTD 454
Query: 325 YSAWVNSLPGSPGLVDYTLEPLH----VLLDSQDPRREALRRALSQYLTDRARWRDCSRP 380
+ W +S+ +P L+ L P++ V + + +++ L RA+ Y+ + + R C
Sbjct: 455 FVNWASSINDAPVLISQKLSPIYNLVPVKMKNAHLKKQNLERAIEDYINEFS-VRKC-HT 512
Query: 381 CPPGRQKSPRD-PCQCVC 397
C G D C C C
Sbjct: 513 CQNGGTVILMDGKCLCAC 530
>gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Homo
sapiens]
Length = 823
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/81 (27%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Query: 417 LEVTFIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGG 476
+ +T ++ + G + T+ +V+L G Q ++ T+ + NP W + DF G
Sbjct: 358 ISITLLEGKNVSGG--SMTEMFVQLKLGDQRYKSKTLCKSANPQWQEQFDF-HYFSDRMG 414
Query: 477 PLRLQVWDQDSGRDDDLLGTC 497
L ++VW +D+ + ++ LGTC
Sbjct: 415 ILDIEVWGKDNKKHEERLGTC 435
Score = 33.5 bits (75), Expect = 0.52
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
Query: 427 LWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQD 486
L D+ +D + L G L+T TV+ N NP W+ F + L + V+D+D
Sbjct: 522 LAADFSGKSDPFCLLELGNDRLQTHTVYKNLNPEWNKVFTF--PIKDIHDVLEVTVFDED 579
Query: 487 SGRDDDLLG 495
+ D LG
Sbjct: 580 GDKPPDFLG 588
>gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Homo
sapiens]
Length = 878
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/81 (27%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Query: 417 LEVTFIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGG 476
+ +T ++ + G + T+ +V+L G Q ++ T+ + NP W + DF G
Sbjct: 358 ISITLLEGKNVSGG--SMTEMFVQLKLGDQRYKSKTLCKSANPQWQEQFDF-HYFSDRMG 414
Query: 477 PLRLQVWDQDSGRDDDLLGTC 497
L ++VW +D+ + ++ LGTC
Sbjct: 415 ILDIEVWGKDNKKHEERLGTC 435
Score = 33.5 bits (75), Expect = 0.52
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
Query: 427 LWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQD 486
L D+ +D + L G L+T TV+ N NP W+ F + L + V+D+D
Sbjct: 522 LAADFSGKSDPFCLLELGNDRLQTHTVYKNLNPEWNKVFTF--PIKDIHDVLEVTVFDED 579
Query: 487 SGRDDDLLG 495
+ D LG
Sbjct: 580 GDKPPDFLG 588
>gi|103472031 family with sequence similarity 62 (C2 domain
containing), member C [Homo sapiens]
Length = 886
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Query: 435 TDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQDSGRDDDL 493
+D Y K+ G Q R+ T++ N NP W+ +F V G L + ++D+D+ RDD L
Sbjct: 331 SDPYAKVSIGLQHFRSRTIYRNLNPTWNEVFEF-MVYEVPGQDLEVDLYDEDTDRDDFL 388
>gi|116174754 phospholipase A2, group IVD [Homo sapiens]
Length = 818
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 416 QLEVTFIQAWGL-WGDWFTATDAYVKLFFG---GQELRTSTVWDNNNPIWSVRLDFGDVL 471
QL V ++A L W D + D YV L G + +T T+ D ++P+W+ F +
Sbjct: 23 QLTVRVLEARNLRWADLLSEADPYVILQLSTAPGMKFKTKTLTDTSHPVWNEAFRFL-IQ 81
Query: 472 LATGGPLRLQVWDQDSGRDDDL 493
L L ++D+DS +DD+
Sbjct: 82 SQVKNVLELSIYDEDSVTEDDI 103
>gi|122937514 unc-13 homolog C [Homo sapiens]
Length = 2214
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 7/94 (7%)
Query: 415 AQLEVTFIQAWGLWG-DWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLA 473
A++ +T + A GL D ++D YV + G + RT T++ N NP+W + F
Sbjct: 1220 AKITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFGNLNPVWDEKFYF--ECHN 1277
Query: 474 TGGPLRLQVWDQDSGRDDDLLGTCDQAPKSGSHE 507
+ ++++VWD+ DDD+ Q K S +
Sbjct: 1278 STDRIKVRVWDE----DDDIKSRVKQHFKKESDD 1307
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 415 AQLEVTFIQAWGLWG-DWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLA 473
A++ +T + A GL D ++D YV + G + RT T++ N NP+W F
Sbjct: 764 AKISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHF--ECHN 821
Query: 474 TGGPLRLQVWDQDSGRDDDLLGTCDQAPKSGSHE 507
+ ++++VWD+ DDD+ Q K S +
Sbjct: 822 SSDRIKVRVWDE----DDDIKSRVKQRFKRESDD 851
>gi|4557391 complement component 8, beta polypeptide preproprotein
[Homo sapiens]
Length = 591
Score = 38.5 bits (88), Expect = 0.016
Identities = 54/265 (20%), Positives = 99/265 (37%), Gaps = 45/265 (16%)
Query: 189 LHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALRTCELALEG 248
LH +F + + LP ++ Y L ++GTH+I LGG + +
Sbjct: 313 LHYEFLQRVKRLPLEYSYGE---YRDLFRDFGTHYITEAVLGGIYEYTLVMNKEAMERGD 369
Query: 249 LTDNEVEDC---------LTVEAQVNIGIH-GSISAEAKACEEKKKKHKMTASFHQTYRE 298
T N V C E V++G+ G +++ K+ M R
Sbjct: 370 YTLNNVHACAKNDFKIGGAIEEVYVSLGVSVGKCRGILNEIKDRNKRDTMVEDLVVLVR- 428
Query: 299 RHSEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQD---- 354
GG I L + + W +++ +P ++ +EPL+ L+ + D
Sbjct: 429 ------GGASEHITTLAYQELPTADLMQEWGDAVQYNPAIIKVKVEPLYELVTATDFAYS 482
Query: 355 -PRREALRRALSQYLTDRARWRDCSRPCP-PGRQKSPRDPCQCVCHGSAVTTQDCCPRQR 412
R+ +++AL ++ + + C+ PC G C C+C + +
Sbjct: 483 STVRQNMKQALEEFQKEVSSCH-CA-PCQGNGVPVLKGSRCDCICPVGS----------Q 530
Query: 413 GLAQLEVTFIQ------AWGLWGDW 431
GLA EV++ + W W +W
Sbjct: 531 GLA-CEVSYRKNTPIDGKWNCWSNW 554
>gi|110611226 UNC13 (C. elegans)-like [Homo sapiens]
Length = 1591
Score = 38.1 bits (87), Expect = 0.021
Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 415 AQLEVTFIQAWGLWG-DWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLA 473
A++ +T + A GL D ++D YV + + RT T++ N NP+W + F
Sbjct: 600 AKITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTKTIFGNLNPVWEEKFHF--ECHN 657
Query: 474 TGGPLRLQVWDQDSGRDDDLLGTCDQAPKSGSHE 507
+ ++++VWD+ DDD+ Q K S +
Sbjct: 658 SSDRIKVRVWDE----DDDIKSRVKQRLKRESDD 687
>gi|34740331 otoferlin isoform a [Homo sapiens]
Length = 1997
Score = 37.4 bits (85), Expect = 0.036
Identities = 17/55 (30%), Positives = 31/55 (56%)
Query: 436 DAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQDSGRD 490
D YV++FF GQ+ +TS + P+W+ ++ F D+ +++Q+ D D D
Sbjct: 453 DPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVND 507
>gi|14149680 extended synaptotagmin-like protein 1 [Homo sapiens]
Length = 1104
Score = 37.0 bits (84), Expect = 0.047
Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 435 TDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQDSGRDDDLL 494
+D YVKL G+ R+ V ++ NP W+ + V G L ++V+D+D + DD L
Sbjct: 674 SDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEV-IVTSVPGQELEVEVFDKDLDK-DDFL 731
Query: 495 GTC 497
G C
Sbjct: 732 GRC 734
>gi|119120884 fer-1-like 6 [Homo sapiens]
Length = 1857
Score = 35.8 bits (81), Expect = 0.11
Identities = 18/62 (29%), Positives = 33/62 (53%)
Query: 429 GDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQDSG 488
GD D +V++ F GQ RT+ + +P+W ++ F ++ +++QVWD+ S
Sbjct: 272 GDSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEMFPPLCRRVKIQVWDEGSM 331
Query: 489 RD 490
D
Sbjct: 332 ND 333
>gi|27477109 itchy homolog E3 ubiquitin protein ligase [Homo
sapiens]
Length = 862
Score = 33.9 bits (76), Expect = 0.40
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Query: 415 AQLEVTFIQAWGLWG--DWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLL 472
+QL++T I A +WF YV++ GQ +T + N+P W L V++
Sbjct: 18 SQLQITVISAKLKENKKNWF-GPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLT---VIV 73
Query: 473 ATGGPLRLQVWDQDSGRDDDLLGT 496
L +VW + + D LLGT
Sbjct: 74 TPVSKLHFRVWSHQTLKSDVLLGT 97
>gi|227496504 multiple C2 domains, transmembrane 2 isoform 3 [Homo
sapiens]
Length = 306
Score = 33.5 bits (75), Expect = 0.52
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
Query: 427 LWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQD 486
L D+ +D + L G L+T TV+ N NP W+ F + L + V+D+D
Sbjct: 110 LAADFSGKSDPFCLLELGNDRLQTHTVYKNLNPEWNKVFTF--PIKDIHDVLEVTVFDED 167
Query: 487 SGRDDDLLG 495
+ D LG
Sbjct: 168 GDKPPDFLG 176
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor
[Homo sapiens]
Length = 1584
Score = 32.7 bits (73), Expect = 0.89
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 11/74 (14%)
Query: 362 RALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQ------CVCHGSAVTTQDCCPRQRGLA 415
RA+ + + W CS C GRQ+ R+ C C G V T+DC +Q
Sbjct: 464 RAVDGNWNEWSSWSACSASCSQGRQQRTRE-CNGPSYGGAECQGHWVETRDCFLQQ---C 519
Query: 416 QLEVTFIQAWGLWG 429
++ + QAW WG
Sbjct: 520 PVDGKW-QAWASWG 532
>gi|19718759 myoferlin isoform b [Homo sapiens]
Length = 2048
Score = 32.7 bits (73), Expect = 0.89
Identities = 21/91 (23%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 410 RQRGLAQLEVTFIQA----WGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRL 465
R + Q++ F Q +G D D +V++ F G+++ T+ + N NP W+ +
Sbjct: 366 RAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVV 425
Query: 466 DFGDVLLATGGPLRLQVWDQDSGRDDDLLGT 496
+ + ++L ++D D +D++GT
Sbjct: 426 NLQIKFPSVCEKIKLTIYDWDRLTKNDVVGT 456
>gi|7305053 myoferlin isoform a [Homo sapiens]
Length = 2061
Score = 32.7 bits (73), Expect = 0.89
Identities = 21/91 (23%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 410 RQRGLAQLEVTFIQA----WGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRL 465
R + Q++ F Q +G D D +V++ F G+++ T+ + N NP W+ +
Sbjct: 366 RAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVV 425
Query: 466 DFGDVLLATGGPLRLQVWDQDSGRDDDLLGT 496
+ + ++L ++D D +D++GT
Sbjct: 426 NLQIKFPSVCEKIKLTIYDWDRLTKNDVVGT 456
>gi|148529000 deleted in bladder cancer 1 [Homo sapiens]
Length = 761
Score = 32.0 bits (71), Expect = 1.5
Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 3/55 (5%)
Query: 183 VVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALT 237
V H PL P+F+R++ L +TQ +I YGTH + + LGG ALT
Sbjct: 91 VRHPVPLMPEFQRSIRLLGRR--PTTQQFIDTIIKKYGTHLLISATLGGE-EALT 142
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 32.0 bits (71), Expect = 1.5
Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 8/107 (7%)
Query: 415 AQLEVTFIQAWGLWG-DWFTATDAYVKLFF-----GGQELRTSTVWDNNNPIWSVRLDFG 468
+ L+ T I+A GL D D YVKL +LRT T+ + NPIW+ L +
Sbjct: 407 SSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYH 466
Query: 469 DVL--LATGGPLRLQVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLN 513
+ LR+ V D+D ++ +G + K R N N
Sbjct: 467 GITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN 513
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 32.0 bits (71), Expect = 1.5
Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 8/107 (7%)
Query: 415 AQLEVTFIQAWGLWG-DWFTATDAYVKLFF-----GGQELRTSTVWDNNNPIWSVRLDFG 468
+ L+ T I+A GL D D YVKL +LRT T+ + NPIW+ L +
Sbjct: 403 SSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYH 462
Query: 469 DVL--LATGGPLRLQVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLN 513
+ LR+ V D+D ++ +G + K R N N
Sbjct: 463 GITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN 509
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 31.6 bits (70), Expect = 2.0
Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 15/62 (24%)
Query: 374 WRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVTFIQAWGLWGDWFT 433
WR SR CP SP D C G A + C P + + WGLW W T
Sbjct: 2797 WRSRSRLCP-----SPGDSS---CPGDATQEEPCSPPVCPVPSI-------WGLWAPWST 2841
Query: 434 AT 435
+
Sbjct: 2842 CS 2843
Score = 30.8 bits (68), Expect = 3.4
Identities = 22/68 (32%), Positives = 27/68 (39%), Gaps = 9/68 (13%)
Query: 372 ARWRDCSRPCPPGRQKSPRDPCQCVC--HGSAVTTQDC----CPRQRGLAQLEVT--FIQ 423
+ W CS+PC G+ +S C C HG A T + QR T
Sbjct: 3415 SEWTMCSQPCR-GQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDG 3473
Query: 424 AWGLWGDW 431
AWG WG W
Sbjct: 3474 AWGPWGPW 3481
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,206,718
Number of Sequences: 37866
Number of extensions: 1150248
Number of successful extensions: 3102
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 3006
Number of HSP's gapped (non-prelim): 125
length of query: 555
length of database: 18,247,518
effective HSP length: 107
effective length of query: 448
effective length of database: 14,195,856
effective search space: 6359743488
effective search space used: 6359743488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.