Guide to the Human Genome
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Name: PRF1 Sequence: fasta or formatted (555aa) NCBI GI: 40254808
Description:

perforin 1 precursor

Referenced in:

Complement
T cells

Other entries for this name:
alt mRNA [555aa] perforin 1 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.3         46           2
 C cysteine            3.6         20           2
 D aspartate           5.8         32           3
 E glutamate           4.3         24           2
 F phenylalanine       3.2         18           2
 G glycine             7.9         44           3
 H histidine           4.5         25           2
 I isoleucine          2.2         12           1
 K lysine              3.1         17           4
 L leucine            11.2         62           5
 M methionine          0.5          3           1
 N asparagine          3.1         17           3
 P proline             5.9         33           2
 Q glutamine           4.9         27           1
 R arginine            7.6         42           2
 S serine              6.8         38           2
 T threonine           6.5         36           2
 V valine              6.5         36           2
 W tryptophan          2.2         12           1
 Y tyrosine            2.0         11           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   perforin 1 precursor 
PRF1                  1.000   perforin 1 precursor 
C6                    0.055   complement component 6 precursor 
C6                    0.055   complement component 6 precursor 
C8A                   0.037   complement component 8, alpha polypeptide precursor [...
C7                    0.033   complement component 7 precursor 
MCTP1                 0.019   multiple C2 domains, transmembrane 1 isoform S [Homo...
MCTP1                 0.019   multiple C2 domains, transmembrane 1 isoform L [Hom...
RASAL1                0.018   RAS protein activator like 1 
C9                    0.015   complement component 9 precursor 
MCTP2                 0.015   multiple C2 domains, transmembrane 2 isoform 2 [Hom...
MCTP2                 0.015   multiple C2 domains, transmembrane 2 isoform 1 [Hom...
ESYT3                 0.014   family with sequence similarity 62 (C2 domain conta...
PLA2G4D               0.013   phospholipase A2, group IVD 
UNC13C                0.013   unc-13 homolog C 
UNC13A                0.013   unc-13 homolog A 
C8B                   0.012   complement component 8, beta polypeptide preproprotei...
UNC13B                0.011   UNC13 (C. elegans)-like 
OTOF                  0.011   otoferlin isoform a 
ESYT1                 0.011   extended synaptotagmin-like protein 1 
FER1L6                0.010   fer-1-like 6 
ITCH                  0.008   itchy homolog E3 ubiquitin protein ligase 
MCTP2                 0.007   multiple C2 domains, transmembrane 2 isoform 3 [Hom...
BAI1                  0.007   brain-specific angiogenesis inhibitor 1 precursor [...
MYOF                  0.007   myoferlin isoform b 
MYOF                  0.007   myoferlin isoform a 
DBC1                  0.006   deleted in bladder cancer 1 
RPH3A                 0.006   rabphilin 3A homolog isoform 1 
RPH3A                 0.006   rabphilin 3A homolog isoform 2 
SSPO                  0.006   SCO-spondin 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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