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Search of human proteins with 40217617
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40217617 potassium channel tetramerisation domain containing
1 isoform a [Homo sapiens]
(257 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218505694 potassium channel tetramerisation domain containing... 525 e-149
gi|209969708 potassium channel tetramerisation domain containing... 525 e-149
gi|40217617 potassium channel tetramerisation domain containing ... 525 e-149
gi|194018443 potassium channel tetramerisation domain containing... 425 e-119
gi|194018441 potassium channel tetramerisation domain containing... 425 e-119
gi|194018439 potassium channel tetramerisation domain containing... 352 2e-97
gi|189571693 potassium channel tetramerisation domain containing... 110 2e-24
gi|189571691 potassium channel tetramerisation domain containing... 110 2e-24
gi|71143104 potassium channel tetramerisation domain containing ... 102 4e-22
gi|146198864 potassium channel tetramerisation domain containing... 88 6e-18
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens] 76 3e-14
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens] 76 3e-14
gi|19923973 potassium channel tetramerisation domain containing ... 72 5e-13
gi|55926200 potassium channel tetramerisation domain containing ... 70 2e-12
gi|38198663 potassium channel tetramerisation domain containing ... 69 3e-12
gi|155369221 potassium channel tetramerisation domain containing... 68 7e-12
gi|23308551 potassium channel tetramerisation domain containing ... 62 4e-10
gi|142356950 potassium channel tetramerisation domain containing... 61 8e-10
gi|51036594 potassium channel tetramerisation domain containing ... 58 9e-09
gi|13994353 potassium channel tetramerisation domain containing ... 57 2e-08
gi|45387953 potassium channel tetramerization domain containing ... 54 1e-07
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens] 53 2e-07
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo... 52 4e-07
gi|30578412 potassium channel tetramerisation domain containing ... 51 1e-06
gi|169234778 potassium channel tetramerisation domain containing... 50 1e-06
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 49 3e-06
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 49 4e-06
gi|53829365 potassium channel tetramerisation domain containing ... 49 4e-06
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 47 1e-05
gi|46255026 potassium channel tetramerisation domain containing ... 47 2e-05
>gi|218505694 potassium channel tetramerisation domain containing 1
isoform b [Homo sapiens]
Length = 865
Score = 525 bits (1352), Expect = e-149
Identities = 257/257 (100%), Positives = 257/257 (100%)
Query: 1 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60
MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF
Sbjct: 609 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 668
Query: 61 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 120
DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM
Sbjct: 669 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 728
Query: 121 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 180
LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN
Sbjct: 729 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 788
Query: 181 AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR 240
AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR
Sbjct: 789 AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR 848
Query: 241 RTPRVPSVIRIKQEPLD 257
RTPRVPSVIRIKQEPLD
Sbjct: 849 RTPRVPSVIRIKQEPLD 865
>gi|209969708 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 525 bits (1352), Expect = e-149
Identities = 257/257 (100%), Positives = 257/257 (100%)
Query: 1 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60
MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF
Sbjct: 1 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60
Query: 61 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 120
DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM
Sbjct: 61 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 120
Query: 121 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 180
LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN
Sbjct: 121 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 180
Query: 181 AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR 240
AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR
Sbjct: 181 AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR 240
Query: 241 RTPRVPSVIRIKQEPLD 257
RTPRVPSVIRIKQEPLD
Sbjct: 241 RTPRVPSVIRIKQEPLD 257
>gi|40217617 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 525 bits (1352), Expect = e-149
Identities = 257/257 (100%), Positives = 257/257 (100%)
Query: 1 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60
MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF
Sbjct: 1 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60
Query: 61 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 120
DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM
Sbjct: 61 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 120
Query: 121 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 180
LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN
Sbjct: 121 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 180
Query: 181 AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR 240
AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR
Sbjct: 181 AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR 240
Query: 241 RTPRVPSVIRIKQEPLD 257
RTPRVPSVIRIKQEPLD
Sbjct: 241 RTPRVPSVIRIKQEPLD 257
>gi|194018443 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 425 bits (1093), Expect = e-119
Identities = 205/257 (79%), Positives = 228/257 (88%)
Query: 1 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60
MSR +TRSP SPL QGIP PAQLTKSNAPVHIDVGGHMYTSSLATLTKYP+SRI RLF
Sbjct: 27 MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF 86
Query: 61 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 120
+GTEPIVLDSLKQHYFIDRDG++FRY+L+FLRTSKLL+PDDFKD++LLYEEA+Y+QLQPM
Sbjct: 87 NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM 146
Query: 121 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 180
+ E+ERW+Q++E R SR C+CLVVRV PDLGERI LSG+K+LIEEVFPE GDVMCNSVN
Sbjct: 147 VRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVN 206
Query: 181 AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR 240
AGWN D THVIRFPLNGYC LNSVQVLERL QRGF + SCGGGVDSSQFSEYVL RE R
Sbjct: 207 AGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRGFSVAASCGGGVDSSQFSEYVLCREER 266
Query: 241 RTPRVPSVIRIKQEPLD 257
R P+ +RIKQEPLD
Sbjct: 267 RPQPTPTAVRIKQEPLD 283
>gi|194018441 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 425 bits (1093), Expect = e-119
Identities = 205/257 (79%), Positives = 228/257 (88%)
Query: 1 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60
MSR +TRSP SPL QGIP PAQLTKSNAPVHIDVGGHMYTSSLATLTKYP+SRI RLF
Sbjct: 27 MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF 86
Query: 61 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 120
+GTEPIVLDSLKQHYFIDRDG++FRY+L+FLRTSKLL+PDDFKD++LLYEEA+Y+QLQPM
Sbjct: 87 NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM 146
Query: 121 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 180
+ E+ERW+Q++E R SR C+CLVVRV PDLGERI LSG+K+LIEEVFPE GDVMCNSVN
Sbjct: 147 VRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVN 206
Query: 181 AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR 240
AGWN D THVIRFPLNGYC LNSVQVLERL QRGF + SCGGGVDSSQFSEYVL RE R
Sbjct: 207 AGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRGFSVAASCGGGVDSSQFSEYVLCREER 266
Query: 241 RTPRVPSVIRIKQEPLD 257
R P+ +RIKQEPLD
Sbjct: 267 RPQPTPTAVRIKQEPLD 283
>gi|194018439 potassium channel tetramerisation domain containing 15
isoform 1 [Homo sapiens]
Length = 234
Score = 352 bits (903), Expect = 2e-97
Identities = 167/205 (81%), Positives = 187/205 (91%)
Query: 1 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60
MSR +TRSP SPL QGIP PAQLTKSNAPVHIDVGGHMYTSSLATLTKYP+SRI RLF
Sbjct: 27 MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF 86
Query: 61 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 120
+GTEPIVLDSLKQHYFIDRDG++FRY+L+FLRTSKLL+PDDFKD++LLYEEA+Y+QLQPM
Sbjct: 87 NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM 146
Query: 121 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 180
+ E+ERW+Q++E R SR C+CLVVRV PDLGERI LSG+K+LIEEVFPE GDVMCNSVN
Sbjct: 147 VRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVN 206
Query: 181 AGWNHDSTHVIRFPLNGYCHLNSVQ 205
AGWN D THVIRFPLNGYC LNSVQ
Sbjct: 207 AGWNQDPTHVIRFPLNGYCRLNSVQ 231
>gi|189571693 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 110 bits (274), Expect = 2e-24
Identities = 49/91 (53%), Positives = 72/91 (79%), Gaps = 1/91 (1%)
Query: 31 PVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNF 90
PV ++VGGH+YT+SL TLT+YP+S +G +F G P D + +YFIDRDG +FRY+LNF
Sbjct: 13 PVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDP-QGNYFIDRDGPLFRYVLNF 71
Query: 91 LRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121
LRTS+L +P DFK++ LL +EA ++Q++P++
Sbjct: 72 LRTSELTLPLDFKEFDLLRKEADFYQIEPLI 102
>gi|189571691 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 110 bits (274), Expect = 2e-24
Identities = 49/91 (53%), Positives = 72/91 (79%), Gaps = 1/91 (1%)
Query: 31 PVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNF 90
PV ++VGGH+YT+SL TLT+YP+S +G +F G P D + +YFIDRDG +FRY+LNF
Sbjct: 13 PVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDP-QGNYFIDRDGPLFRYVLNF 71
Query: 91 LRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121
LRTS+L +P DFK++ LL +EA ++Q++P++
Sbjct: 72 LRTSELTLPLDFKEFDLLRKEADFYQIEPLI 102
>gi|71143104 potassium channel tetramerisation domain containing 21
[Homo sapiens]
Length = 260
Score = 102 bits (253), Expect = 4e-22
Identities = 48/91 (52%), Positives = 70/91 (76%), Gaps = 1/91 (1%)
Query: 31 PVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNF 90
P+ ++VGG +YT+SLATLT +P+S +G +F G P DS + + FIDRDG++FRYILNF
Sbjct: 4 PITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDS-QGNCFIDRDGKVFRYILNF 62
Query: 91 LRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121
LRTS L +P+DF++ LL EA ++Q+QP++
Sbjct: 63 LRTSHLDLPEDFQEMGLLRREADFYQVQPLI 93
>gi|146198864 potassium channel tetramerisation domain containing 4
[Homo sapiens]
Length = 259
Score = 88.2 bits (217), Expect = 6e-18
Identities = 43/103 (41%), Positives = 73/103 (70%), Gaps = 2/103 (1%)
Query: 34 IDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRT 93
++VGG++Y + TLTKYP++ + + +G D+ HYFIDRDG +FR++LNFLR
Sbjct: 37 LNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDA-DGHYFIDRDGLLFRHVLNFLRN 95
Query: 94 SKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRETGR 135
+LL+P+ F++ LL +EA++FQL+ + E++ RW++++ T R
Sbjct: 96 GELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPR 138
>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
Length = 229
Score = 76.3 bits (186), Expect = 3e-14
Identities = 34/90 (37%), Positives = 60/90 (66%), Gaps = 1/90 (1%)
Query: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 91
V ++VGG ++T+ +T+ ++P SR+ R+ DG + + F+DRDG +F +IL+FL
Sbjct: 7 VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQ-EFKMVGGQIFVDRDGDLFSFILDFL 65
Query: 92 RTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121
RT +LL+P +F DY L EA +++L+ ++
Sbjct: 66 RTHQLLLPTEFSDYLRLQREALFYELRSLV 95
>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
Length = 272
Score = 76.3 bits (186), Expect = 3e-14
Identities = 34/90 (37%), Positives = 60/90 (66%), Gaps = 1/90 (1%)
Query: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 91
V ++VGG ++T+ +T+ ++P SR+ R+ DG + + F+DRDG +F +IL+FL
Sbjct: 7 VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQ-EFKMVGGQIFVDRDGDLFSFILDFL 65
Query: 92 RTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121
RT +LL+P +F DY L EA +++L+ ++
Sbjct: 66 RTHQLLLPTEFSDYLRLQREALFYELRSLV 95
>gi|19923973 potassium channel tetramerisation domain containing 12
[Homo sapiens]
Length = 325
Score = 72.0 bits (175), Expect = 5e-13
Identities = 36/92 (39%), Positives = 60/92 (65%), Gaps = 3/92 (3%)
Query: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEP--IVLDSLKQHYFIDRDGQMFRYILN 89
V ++VGG +Y + T+ P+S + R+F +P + DS K +F+DRDG +FRYIL+
Sbjct: 36 VELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDS-KGRFFLDRDGFLFRYILD 94
Query: 90 FLRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121
+LR +L++PD F + + L EA+YF+L ++
Sbjct: 95 YLRDLQLVLPDYFPERSRLQREAEYFELPELV 126
>gi|55926200 potassium channel tetramerisation domain containing 16
[Homo sapiens]
Length = 428
Score = 69.7 bits (169), Expect = 2e-12
Identities = 70/245 (28%), Positives = 109/245 (44%), Gaps = 52/245 (21%)
Query: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLF----DGTEPIVLDSLKQHYFIDRDGQMFRYI 87
V ++VGG +Y + +TL P S + ++F D + DS K +FIDRDG +FRYI
Sbjct: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDS-KGRFFIDRDGFLFRYI 85
Query: 88 LNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM--LLEMERWKQ-----------DRETG 134
L++LR ++++PD F + L EA+YFQL + LL + KQ D G
Sbjct: 86 LDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQG 145
Query: 135 RFSRPCE--------------CLVVRVAPDLGE------------RITLSGDKSLIEEVF 168
+R C + R + LG RI + G SL +EVF
Sbjct: 146 SDTRICPPSSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVF 205
Query: 169 PEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSS 228
E + + A + S ++F HL + + L + GF +V +C V +S
Sbjct: 206 GETLNESRDPDRAPERYTSRFYLKFK-----HLE--RAFDMLSECGFHMV-ACNSSVTAS 257
Query: 229 QFSEY 233
++Y
Sbjct: 258 FINQY 262
>gi|38198663 potassium channel tetramerisation domain containing 8
[Homo sapiens]
Length = 473
Score = 69.3 bits (168), Expect = 3e-12
Identities = 38/126 (30%), Positives = 67/126 (53%), Gaps = 10/126 (7%)
Query: 5 LITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTE 64
+++ S + + P P + V ++VGG +Y + +TL P+S + +F +
Sbjct: 19 MVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSS 78
Query: 65 P---------IVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYF 115
P + DS + +FIDRDG +FRY+L++LR +L +P+ F + L EA+YF
Sbjct: 79 PRGGARRRGELPRDS-RARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYF 137
Query: 116 QLQPML 121
QL ++
Sbjct: 138 QLTDLV 143
>gi|155369221 potassium channel tetramerisation domain containing 19
[Homo sapiens]
Length = 926
Score = 68.2 bits (165), Expect = 7e-12
Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 13/109 (11%)
Query: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 91
+ + VG H Y ++L TL KYPE L + + + Q I DGQMFR+ILNFL
Sbjct: 398 IKVYVGSHWYATTLQTLLKYPE-----LLSNPQRVYWITYGQTLLIHGDGQMFRHILNFL 452
Query: 92 RTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLE-------MERWKQDRET 133
R KL +P +FK++ L +E + + + P L E + W Q++E+
Sbjct: 453 RLGKLFLPSEFKEWPLFCQEVEEYHI-PSLSEALAQCEAYKSWTQEKES 500
Score = 54.3 bits (129), Expect = 1e-07
Identities = 37/116 (31%), Positives = 59/116 (50%), Gaps = 6/116 (5%)
Query: 33 HIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLR 92
H +VGG ++ + L+++P+S + + + S Q FIDRDG FR++ +L
Sbjct: 16 HFNVGGWHFSVPRSKLSQFPDSLLWK----EASALTSSESQRLFIDRDGSTFRHVHYYLY 71
Query: 93 TSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCECLVVRVA 148
TSKL + LLYE+A QL P+L ++ K+ + R RP + V A
Sbjct: 72 TSKLSF-SSCAELNLLYEQALGLQLMPLLQTLDNLKEGKHHLRV-RPADLPVAERA 125
Score = 42.7 bits (99), Expect = 3e-04
Identities = 19/44 (43%), Positives = 30/44 (68%), Gaps = 1/44 (2%)
Query: 84 FRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERW 127
FR+I+NFLR+ K+L+PD+F + +L E + ++ P L E RW
Sbjct: 211 FRFIVNFLRSQKILLPDNFSNIDVLEAEVEILEI-PALTEAVRW 253
Score = 33.5 bits (75), Expect = 0.19
Identities = 20/66 (30%), Positives = 37/66 (56%), Gaps = 7/66 (10%)
Query: 40 MYTSSLATLTKYPESRIGRL-FDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLI 98
+YT +L L KYP+S +G+L + T LD +I +G +F+++ N+L T +L +
Sbjct: 286 LYTMALGLLVKYPDSALGQLRIEST----LDG--SRLYITGNGVLFQHVKNWLGTCRLPL 339
Query: 99 PDDFKD 104
+ +
Sbjct: 340 TETISE 345
>gi|23308551 potassium channel tetramerisation domain containing 7
[Homo sapiens]
Length = 289
Score = 62.4 bits (150), Expect = 4e-10
Identities = 40/117 (34%), Positives = 65/117 (55%), Gaps = 5/117 (4%)
Query: 10 PASPLNNQ-GIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVL 68
PA+P Q G P + V +++GG +T+ L+TL Y ++ + +F G I
Sbjct: 30 PATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPT 89
Query: 69 DSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME 125
DS + YFIDRDG F +LNFLR+ L + + +Y+EA+Y+ + P+L ++E
Sbjct: 90 DS-EGRYFIDRDGTHFGDVLNFLRSGDLPPRERVR---AVYKEAQYYAIGPLLEQLE 142
>gi|142356950 potassium channel tetramerisation domain containing 14
[Homo sapiens]
Length = 255
Score = 61.2 bits (147), Expect = 8e-10
Identities = 40/132 (30%), Positives = 72/132 (54%), Gaps = 14/132 (10%)
Query: 1 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60
+ RP+ + +PL P P + T S V ++VGG +T++L TL K+P S++ +F
Sbjct: 7 VERPVGRMTSQTPLPQS--PRPRRPTMSTV-VELNVGGEFHTTTLGTLRKFPGSKLAEMF 63
Query: 61 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKL---LIPDDFKDYTLLYEEAKYFQL 117
D+ + +FIDR FR IL++LRT ++ IP+ +Y EA+++++
Sbjct: 64 SSLAKASTDA-EGRFFIDRPSTYFRPILDYLRTGQVPTQHIPE-------VYREAQFYEI 115
Query: 118 QPMLLEMERWKQ 129
+P++ +E Q
Sbjct: 116 KPLVKLLEDMPQ 127
>gi|51036594 potassium channel tetramerisation domain containing 11
[Homo sapiens]
Length = 232
Score = 57.8 bits (138), Expect = 9e-09
Identities = 25/48 (52%), Positives = 36/48 (75%)
Query: 74 HYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121
HYFIDRDG+ FR+ILNFLR +L +P + + LL EA ++Q++P+L
Sbjct: 23 HYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLL 70
>gi|13994353 potassium channel tetramerisation domain containing 10
[Homo sapiens]
Length = 313
Score = 57.0 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 63/106 (59%), Gaps = 2/106 (1%)
Query: 28 SNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYI 87
S+ V ++VGG +Y +++ TLTK ++ + +F G ++ DS + IDR G+ F I
Sbjct: 30 SSKYVKLNVGGALYYTTMQTLTKQ-DTMLKAMFSGRMEVLTDS-EGWILIDRCGKHFGTI 87
Query: 88 LNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRET 133
LN+LR + +P+ ++ L EAKY+ +Q ++ E + Q+++T
Sbjct: 88 LNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDT 133
>gi|45387953 potassium channel tetramerization domain containing 18
[Homo sapiens]
Length = 426
Score = 54.3 bits (129), Expect = 1e-07
Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 2/84 (2%)
Query: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 91
+ ++VGG +YT+ +L ++ +S + +F G P+ D IDRDG++F+Y+L++L
Sbjct: 14 LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDE-SGACVIDRDGRLFKYLLDYL 72
Query: 92 RTSKLLIPDDFKDYTLLYEEAKYF 115
++ IP D + L EEA YF
Sbjct: 73 H-GEVQIPTDEQTRIALQEEADYF 95
>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
Length = 707
Score = 53.1 bits (126), Expect = 2e-07
Identities = 42/118 (35%), Positives = 63/118 (53%), Gaps = 8/118 (6%)
Query: 21 TPAQLTKSNAP----VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYF 76
T A+ S P +H++VGG +++S TLT P+S L G + D F
Sbjct: 6 TAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGA-IF 64
Query: 77 IDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRET 133
IDRD +F ILNFLRT K L P +LL+ EA+++ L P++ ++ R + DR +
Sbjct: 65 IDRDPTVFAPILNFLRT-KELDPRGVHGSSLLH-EAQFYGLTPLVRRLQLREELDRSS 120
>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
sapiens]
Length = 316
Score = 52.4 bits (124), Expect = 4e-07
Identities = 35/140 (25%), Positives = 74/140 (52%), Gaps = 4/140 (2%)
Query: 29 NAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYIL 88
N V ++VGG +Y +++ LT++ ++ + +F G ++ D + IDR G+ F IL
Sbjct: 27 NKYVQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDK-EGWILIDRCGKHFGTIL 84
Query: 89 NFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCECLVVRVA 148
N+LR + +P + ++ L EAKY+ +Q ++ + QD++ + C ++
Sbjct: 85 NYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDS-YQPVCNIPIITSL 143
Query: 149 PDLGERITLSGDKSLIEEVF 168
+ ER+ S K +++ ++
Sbjct: 144 KE-EERLIESSTKPVVKLLY 162
>gi|30578412 potassium channel tetramerisation domain containing 13
[Homo sapiens]
Length = 329
Score = 50.8 bits (120), Expect = 1e-06
Identities = 33/110 (30%), Positives = 63/110 (57%), Gaps = 3/110 (2%)
Query: 25 LTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMF 84
LT ++ V ++VGG ++ ++L TLT ++ + +F G ++ D+ IDR G+ F
Sbjct: 36 LTPNSKYVKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDA-GGWVLIDRSGRHF 93
Query: 85 RYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRET 133
ILN+LR + +P+ ++ L EA+Y+ +Q ++ + + +Q RET
Sbjct: 94 GTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRET 143
>gi|169234778 potassium channel tetramerisation domain containing 17
[Homo sapiens]
Length = 297
Score = 50.4 bits (119), Expect = 1e-06
Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
Query: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 91
V ++VGG ++ ++ TL + +S + RL G E Y IDRD F ILNFL
Sbjct: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
Query: 92 RTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121
R KL++ D + +L EEA+++ + P++
Sbjct: 93 RHGKLVLDKDMAEEGVL-EEAEFYNIGPLI 121
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 49.3 bits (116), Expect = 3e-06
Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 6/112 (5%)
Query: 13 PLNNQGIPTP--AQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDS 70
PL Q +P + ++ + + ++V G + + TL +YP++ +G + D+
Sbjct: 21 PLAQQPLPPAPGVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLG---SSEKEFFYDA 77
Query: 71 LKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLL 122
YF DRD MFR++LNF RT +L P + EE ++ L P L+
Sbjct: 78 DSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQ-ECIQAFDEELAFYGLVPELV 128
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 48.9 bits (115), Expect = 4e-06
Identities = 26/99 (26%), Positives = 56/99 (56%), Gaps = 8/99 (8%)
Query: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLFD-GTEPIVLDSLKQH------YFIDRDGQMF 84
V+++VGG + +TL ++P +R+G+L +E +L+ + Y+ DR+ +F
Sbjct: 17 VNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLF 76
Query: 85 RYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLE 123
RY+LNF T KL + ++ ++ +E +Y+ + + ++
Sbjct: 77 RYVLNFYYTGKLHVMEELCVFSFC-QEIEYWGINELFID 114
>gi|53829365 potassium channel tetramerisation domain containing 2
[Homo sapiens]
Length = 263
Score = 48.9 bits (115), Expect = 4e-06
Identities = 35/104 (33%), Positives = 58/104 (55%), Gaps = 5/104 (4%)
Query: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQH---YFIDRDGQMFRYIL 88
V ++VGG + ++ TL + P+S + RL +P LDS K Y IDRD F IL
Sbjct: 74 VRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDP-ELDSDKDETGAYLIDRDPTYFGPIL 132
Query: 89 NFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRE 132
N+LR KL+I + + +L EEA+++ + ++ ++ +D E
Sbjct: 133 NYLRHGKLIITKELAEEGVL-EEAEFYNIASLVRLVKERIRDNE 175
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 47.4 bits (111), Expect = 1e-05
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 7/113 (6%)
Query: 13 PLNNQGIPTPAQLTKS---NAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLD 69
P+ + +P P + + +A + ++V G + + TL +YP++ +G
Sbjct: 21 PVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLG---SSERDFFYH 77
Query: 70 SLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLL 122
Q YF DRD +FR+ILNF RT KL P + + EE +F L P ++
Sbjct: 78 PETQQYFFDRDPDIFRHILNFYRTGKLHYP-RHECISAYDEELAFFGLIPEII 129
>gi|46255026 potassium channel tetramerisation domain containing 3
[Homo sapiens]
Length = 815
Score = 47.0 bits (110), Expect = 2e-05
Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 7/102 (6%)
Query: 22 PAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDG 81
PA S V ++VGG +++S TL P+S L G + D FIDRD
Sbjct: 10 PAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGA-IFIDRDP 68
Query: 82 QMFRYILNFLRTSKLLIPDDFKDYTL--LYEEAKYFQLQPML 121
F ILNFLRT +L D + ++ L EA+++ + P++
Sbjct: 69 AAFAPILNFLRTKEL----DLRGVSINVLRHEAEFYGITPLV 106
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,088,889
Number of Sequences: 37866
Number of extensions: 442496
Number of successful extensions: 1126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1038
Number of HSP's gapped (non-prelim): 77
length of query: 257
length of database: 18,247,518
effective HSP length: 100
effective length of query: 157
effective length of database: 14,460,918
effective search space: 2270364126
effective search space used: 2270364126
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.