Search of human proteins with 40068065

Search of human proteins with 40068065

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40068065 hypothetical protein LOC54058 [Homo sapiens]
         (322 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40068065 hypothetical protein LOC54058 [Homo sapiens]              671   0.0  
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    54   2e-07
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               49   8e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    45   7e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    45   7e-05
gi|209977097 tripartite motif-containing 66 [Homo sapiens]             45   7e-05
gi|153792074 proline rich 12 [Homo sapiens]                            45   7e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    44   2e-04
gi|117938768 GNAS complex locus alex [Homo sapiens]                    43   3e-04
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]      43   4e-04
gi|238859557 regulatory factor X1 [Homo sapiens]                       42   6e-04
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    42   6e-04
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    42   6e-04
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    42   6e-04
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    42   6e-04
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       42   6e-04
gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]         42   7e-04
gi|60460889 Myb protein P42POP [Homo sapiens]                          42   7e-04
gi|110349719 titin isoform N2-A [Homo sapiens]                         42   0.001
gi|47132519 Ras association and pleckstrin homology domains 1 is...    42   0.001
gi|21071077 dishevelled-associated activator of morphogenesis 1 ...    42   0.001
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]        41   0.001
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           41   0.001
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           41   0.001
gi|23510413 sorting nexin 26 [Homo sapiens]                            40   0.002
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              40   0.002
gi|40288197 GATA binding protein 6 [Homo sapiens]                      40   0.003
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       40   0.003
gi|32307177 forkhead box G1 [Homo sapiens]                             40   0.003
gi|157785645 SPEG complex locus [Homo sapiens]                         40   0.003

>gi|40068065 hypothetical protein LOC54058 [Homo sapiens]
          Length = 322

 Score =  671 bits (1731), Expect = 0.0
 Identities = 322/322 (100%), Positives = 322/322 (100%)

Query: 1   MARSRLPATSLRKPWKLDRQKLPSPDSGHSLLCGWSPGGKARPAGNTGAWAPAEQFFPAS 60
           MARSRLPATSLRKPWKLDRQKLPSPDSGHSLLCGWSPGGKARPAGNTGAWAPAEQFFPAS
Sbjct: 1   MARSRLPATSLRKPWKLDRQKLPSPDSGHSLLCGWSPGGKARPAGNTGAWAPAEQFFPAS 60

Query: 61  NRTREGGGLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLH 120
           NRTREGGGLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLH
Sbjct: 61  NRTREGGGLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLH 120

Query: 121 LEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPP 180
           LEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPP
Sbjct: 121 LEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPP 180

Query: 181 TGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKE 240
           TGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKE
Sbjct: 181 TGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKE 240

Query: 241 DMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHHHHHHHA 300
           DMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHHHHHHHA
Sbjct: 241 DMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHHHHHHHA 300

Query: 301 VWPPGAATVLQPAPSLWTPGPP 322
           VWPPGAATVLQPAPSLWTPGPP
Sbjct: 301 VWPPGAATVLQPAPSLWTPGPP 322


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 47/141 (33%), Positives = 60/141 (42%), Gaps = 20/141 (14%)

Query: 179  PPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSI 238
            PPT +LP+       P P    LP  P P  ++ QQL QQP     P PQ  P Q+    
Sbjct: 940  PPTPLLPSVKVQSQPPPP----LPPPPHP--SVQQQLQQQPPPPPPPQPQPPPQQQH--- 990

Query: 239  KEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRV----PRAARPRLPAVHHH 294
             +     + LQ  Q    + Q       PP  Q PPH PP      P+ A+P+    HHH
Sbjct: 991  -QPPPRPVHLQPMQFSTHIQQ-----PPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHH 1044

Query: 295  HHHHHAVWPPGAATVLQPAPS 315
               HH    P +   L+ APS
Sbjct: 1045 SPRHHKS-DPYSTGHLREAPS 1064



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 39/141 (27%), Positives = 53/141 (37%), Gaps = 31/141 (21%)

Query: 188 SPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLL 247
           +P+P+   PP    P   QPP     Q  QQP     PPP + P Q + ++K      + 
Sbjct: 749 APAPVPQQPP----PPPQQPPPPPPPQQQQQP--PPPPPPPSMPQQAAPAMKSSPPPFIA 802

Query: 248 LQNAQVHQLVLQNWMLKALPPALQDP-------------PHVPPRVPRAARPRLPAVHHH 294
               QV  L  Q      LP ++ DP             P +PP +P+      P    H
Sbjct: 803 ---TQVPVLEPQ------LPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPP---H 850

Query: 295 HHHHHAVWPPGAATVLQPAPS 315
            + H  V PP     L   PS
Sbjct: 851 LNQHAVVSPPALHNALPQQPS 871



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 38/143 (26%), Positives = 56/143 (39%), Gaps = 19/143 (13%)

Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQR 234
           PP+ PP    P     P  P PP    P++PQ  A  ++  P   +  Q+P       Q 
Sbjct: 760 PPQQPPPPPPPQQQQQPPPPPPP----PSMPQQAAPAMKSSPPPFIATQVP---VLEPQL 812

Query: 235 SGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPH--VPPRVPRAARPRLPAVH 292
            GS+ + +            Q +L +     LPP L  PP    PP + + A    PA+H
Sbjct: 813 PGSVFDPI--------GHFTQPIL-HLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALH 863

Query: 293 HHHHHHHAVWPPGAATVLQPAPS 315
           +      +  P   A  L P P+
Sbjct: 864 NALPQQPS-RPSNRAAALPPKPA 885



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 15/45 (33%), Positives = 18/45 (40%)

Query: 278 PRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
           P+  +   P      HHHHHH  +    A    QP P    P PP
Sbjct: 723 PKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPP 767



 Score = 32.3 bits (72), Expect = 0.58
 Identities = 33/132 (25%), Positives = 43/132 (32%), Gaps = 32/132 (24%)

Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQ--PLIAQIPPPQAFPT 232
           P  +  T ++    P PL   PP   +P  PQPP     Q  Q   P+IA  P P    T
Sbjct: 230 PDLIVQTPVMTVVPPQPLQTPPP---VPPQPQPPPAPAPQPVQSHPPIIAATPQP--VKT 284

Query: 233 QRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVH 292
           ++    K D                          P   DP H PP +P    P+   + 
Sbjct: 285 KKGVKRKAD-----------------------TTTPTTIDPIHEPPSLP--PEPKTTKLG 319

Query: 293 HHHHHHHAVWPP 304
                   V PP
Sbjct: 320 QRRESSRPVKPP 331



 Score = 32.3 bits (72), Expect = 0.58
 Identities = 44/171 (25%), Positives = 62/171 (36%), Gaps = 34/171 (19%)

Query: 169  ALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQ 228
            AL +ALP +       P+   +  A  PP+   P    P  T    LPQ P+     PPQ
Sbjct: 861  ALHNALPQQ-------PSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPM---AQPPQ 910

Query: 229  AF-----PTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKAL-PPALQDPPH------- 275
                   P     +  +  + L  LQ  Q    +L +  +++  PP L  PPH       
Sbjct: 911  VLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQL 970

Query: 276  -VPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQP---APSLWTPGPP 322
               P  P   +P+ P    H        PP     LQP   +  +  P PP
Sbjct: 971  QQQPPPPPPPQPQPPPQQQHQ-------PPPRPVHLQPMQFSTHIQQPPPP 1014



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 12/31 (38%), Positives = 12/31 (38%)

Query: 292 HHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
           HHHHHH      P       P P    P PP
Sbjct: 738 HHHHHHQQMQQAPAPVPQQPPPPPQQPPPPP 768


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 44/145 (30%), Positives = 53/145 (36%), Gaps = 38/145 (26%)

Query: 180 PTGILPTASPS------------PLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPP 227
           P GIL  + P             P  P P +  LPT  QP         Q PL   +PPP
Sbjct: 537 PVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNL-------QGPLHPPLPPP 589

Query: 228 QAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPR 287
                Q+              Q+   HQ   Q       PP  Q PP  PP+ P   +  
Sbjct: 590 HQPQPQQPQQQPPP-------QHQPPHQPPHQP------PPQHQPPPQHPPQHPPQHQ-- 634

Query: 288 LPAVHHHHHHHHAVWPPGAATVLQP 312
               HHHHHHH +V PP    + QP
Sbjct: 635 ----HHHHHHHLSVPPPPLMPMSQP 655



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 42/157 (26%), Positives = 57/157 (36%), Gaps = 47/157 (29%)

Query: 173 ALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPT 232
           AL P  PP  ++P A P P  P PP+       QP  ++ Q  P QPL+    P    P 
Sbjct: 307 ALLPTQPP--VVPQAPPPP--PPPPQ------QQPIRSLFQPQPLQPLLPVQHPHHPSPP 356

Query: 233 QRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVH 292
           Q  G      +E                      P  +  PP V P+ P+        +H
Sbjct: 357 Q--GMHMPPQLE---------------------TPRMMMTPPPVTPQQPK-------NIH 386

Query: 293 HHHHHHHAVWPPGAATVL----QPAPSLWT---PGPP 322
            + H    V  P    +L    QP P++     PGPP
Sbjct: 387 INPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPP 423


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 43/151 (28%), Positives = 53/151 (35%), Gaps = 24/151 (15%)

Query: 165 PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPP-ATIIQQLPQQPLIAQ 223
           PSR AL    PP  PP G  P+     + P PP+   P VP  P  +   Q P  P    
Sbjct: 256 PSR-ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS 314

Query: 224 IPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRA 283
            P P   P   SG             N +  +L  +N  L +  P L  P    P  P  
Sbjct: 315 RPGPPPLPPSSSG-------------NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361

Query: 284 ARPRLPAVHHHHHHHHAVWPPGAATVLQPAP 314
           +    P V           PPG +  L P P
Sbjct: 362 SERPPPPVRD---------PPGRSGPLPPPP 383



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 24/152 (15%)

Query: 174 LPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQ 233
           +PP  P  G  P + P P+ P  PR I  +     +  +   P+QP     PPP  FP  
Sbjct: 169 MPPPRPDVGSKPDSIPPPV-PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP--FPGN 225

Query: 234 RSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPP----ALQDPPHVPPRVPRAARPRLP 289
           R  ++    +    L ++              LPP    AL D P  PP  P   RP + 
Sbjct: 226 RGTALGGGSIRQSPLSSSSPFS------NRPPLPPTPSRALDDKP-PPPPPPVGNRPSI- 277

Query: 290 AVHHHHHHHHAVWPPGAATVLQPAPSLWTPGP 321
                  H  AV PP       P PS  TP P
Sbjct: 278 -------HREAVPPPPPQNNKPPVPS--TPRP 300



 Score = 29.3 bits (64), Expect = 4.9
 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 15/76 (19%)

Query: 165 PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPP----ATIIQQLPQQPL 220
           PS G  G   PP        P+  P P   DPP    P  P PP     +  + LP  P 
Sbjct: 349 PSPGRSGPLPPP--------PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP- 399

Query: 221 IAQIPPPQAFPTQRSG 236
             Q+P      + RSG
Sbjct: 400 --QLPSRSGVDSPRSG 413



 Score = 28.5 bits (62), Expect = 8.4
 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 17/80 (21%)

Query: 168 GALGSALP--PELPP-TGI-LPTASPSP-LAPDPPRIILPTVPQPPATIIQQLPQQPL-- 220
           G+   ALP  P+LP  +G+  P + P P L PD P    P  P P  +I       P   
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCED 448

Query: 221 ----------IAQIPPPQAF 230
                     I+ +PPP+ +
Sbjct: 449 EWESRFYFHPISDLPPPEPY 468


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 43/151 (28%), Positives = 53/151 (35%), Gaps = 24/151 (15%)

Query: 165 PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPP-ATIIQQLPQQPLIAQ 223
           PSR AL    PP  PP G  P+     + P PP+   P VP  P  +   Q P  P    
Sbjct: 256 PSR-ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS 314

Query: 224 IPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRA 283
            P P   P   SG             N +  +L  +N  L +  P L  P    P  P  
Sbjct: 315 RPGPPPLPPSSSG-------------NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361

Query: 284 ARPRLPAVHHHHHHHHAVWPPGAATVLQPAP 314
           +    P V           PPG +  L P P
Sbjct: 362 SERPPPPVRD---------PPGRSGPLPPPP 383



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 24/152 (15%)

Query: 174 LPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQ 233
           +PP  P  G  P + P P+ P  PR I  +     +  +   P+QP     PPP  FP  
Sbjct: 169 MPPPRPDVGSKPDSIPPPV-PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP--FPGN 225

Query: 234 RSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPP----ALQDPPHVPPRVPRAARPRLP 289
           R  ++    +    L ++              LPP    AL D P  PP  P   RP + 
Sbjct: 226 RGTALGGGSIRQSPLSSSSPFS------NRPPLPPTPSRALDDKP-PPPPPPVGNRPSI- 277

Query: 290 AVHHHHHHHHAVWPPGAATVLQPAPSLWTPGP 321
                  H  AV PP       P PS  TP P
Sbjct: 278 -------HREAVPPPPPQNNKPPVPS--TPRP 300



 Score = 29.3 bits (64), Expect = 4.9
 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 15/76 (19%)

Query: 165 PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPP----ATIIQQLPQQPL 220
           PS G  G   PP        P+  P P   DPP    P  P PP     +  + LP  P 
Sbjct: 349 PSPGRSGPLPPP--------PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP- 399

Query: 221 IAQIPPPQAFPTQRSG 236
             Q+P      + RSG
Sbjct: 400 --QLPSRSGVDSPRSG 413



 Score = 28.5 bits (62), Expect = 8.4
 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 17/80 (21%)

Query: 168 GALGSALP--PELPP-TGI-LPTASPSP-LAPDPPRIILPTVPQPPATIIQQLPQQPL-- 220
           G+   ALP  P+LP  +G+  P + P P L PD P    P  P P  +I       P   
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCED 448

Query: 221 ----------IAQIPPPQAF 230
                     I+ +PPP+ +
Sbjct: 449 EWESRFYFHPISDLPPPEPY 468


>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
          Length = 1216

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 47/156 (30%), Positives = 63/156 (40%), Gaps = 28/156 (17%)

Query: 175 PPELPP--------TGILPTASPSPLAPDPPRIILPTVP-QPPAT-------IIQQLPQQ 218
           PPE+ P        + +LP       +P PP+++ P +  QPP         + QQL  Q
Sbjct: 350 PPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQ 409

Query: 219 PLIAQIPPPQ-------AFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQ 271
           P+   I PPQ       A PT ++ SI+        L+ +   Q   Q   L   PP L 
Sbjct: 410 PVC--IVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQ--LPPPPPPLP 465

Query: 272 DPPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAA 307
            PP   P  P+   P LP   H     H   PPG A
Sbjct: 466 HPPPPLPPPPQQPHPPLPPSQHLASSQHES-PPGPA 500


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 53/215 (24%), Positives = 73/215 (33%), Gaps = 25/215 (11%)

Query: 114 GGPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSA 173
           GGP G   E   ED     LQ+ ++    L +       L      +   GP RG     
Sbjct: 681 GGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGG---E 737

Query: 174 LPPELPPTGILPTASPSPLA-------PDPPRIILPTVPQPPATIIQQL-PQQPLIAQIP 225
            P  L  + +   A    L        P PP     T P P   +++   P  PL+   P
Sbjct: 738 TPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPP 797

Query: 226 PPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAAR 285
           PPQ  P+              +L +A           +  L PA +D    PP  P    
Sbjct: 798 PPQLLPS--------------VLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP 843

Query: 286 PRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPG 320
           P +P     H   H + P   +  L+P  SL  PG
Sbjct: 844 PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPG 878



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 36/131 (27%), Positives = 44/131 (33%), Gaps = 44/131 (33%)

Query: 165  PSRGALGSALPP---ELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLI 221
            PS  + G+  PP   E PP    P  +P P  P PP    P +P PP  ++   P  P  
Sbjct: 1440 PSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPP-PLVAPTPSSPPP 1498

Query: 222  AQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPP--R 279
              +PPP                                       PPA+  PP  PP   
Sbjct: 1499 PPLPPPP--------------------------------------PPAMPSPPPPPPPAA 1520

Query: 280  VPRAARPRLPA 290
             P AA P  PA
Sbjct: 1521 APLAAPPEEPA 1531



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 4/64 (6%)

Query: 165  PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQI 224
            P + AL S  PP + PT   P++ P P  P PP   +P+ P PP      L   P     
Sbjct: 1477 PPQPALPSP-PPLVAPT---PSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAA 1532

Query: 225  PPPQ 228
            P P+
Sbjct: 1533 PSPE 1536



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 14/34 (41%), Positives = 16/34 (47%), Gaps = 2/34 (5%)

Query: 175  PPELPPTGILPTASPSPLAPDPPRIILPTVPQPP 208
            PP  PP  + P+     L P PP    P VP PP
Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPP--ATPAVPHPP 1336


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 64/238 (26%), Positives = 83/238 (34%), Gaps = 47/238 (19%)

Query: 116 PEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSAL- 174
           PE   L P  E+ P   L  AL   R L     E+  L         S P   +  S L 
Sbjct: 462 PEASRLSPPPEELPASPLPEALHLSRPL-----EESPLSPPPEESPLSPPPESSPFSPLE 516

Query: 175 ------PPELPPTGIL-------PTASP-------SPLAPDPPRIILPTVPQPPATIIQQ 214
                 P E PP+  L       P ASP       SPL+P P    LPT P P A+ +  
Sbjct: 517 ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE--LPTSPPPEASRLSP 574

Query: 215 LPQQPLIA-------QIPPPQA---FPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLK 264
            P++  ++         PPP+A   FP      +     E  L    +  +L        
Sbjct: 575 PPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP 634

Query: 265 ALPPALQDPPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
             PP  + P   PP V R +   LP V         + PP   + L P P      PP
Sbjct: 635 MSPPPEESPMSPPPEVSRLS--PLPVVSR-------LSPPPEESPLSPPPEESPTSPP 683



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 42/149 (28%), Positives = 54/149 (36%), Gaps = 56/149 (37%)

Query: 165  PSRGALGSALPPELPPTGIL--------------PTASP---SPLAPDP----------P 197
            P    + +A PP L P G L              P A+P   +P++P P          P
Sbjct: 938  PLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVP 997

Query: 198  RIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLV 257
             +ILP  P  P       P  P++ +  PPQ  P               LLQ    H LV
Sbjct: 998  PMILPPSPGSPVG-----PASPILMEPLPPQCSP---------------LLQ----HSLV 1033

Query: 258  LQNWMLKALPPALQDPPHVPPRVPRAARP 286
             QN      PP+   PP +P  VP    P
Sbjct: 1034 PQN-----SPPSQCSPPALPLSVPSPLSP 1057



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 7/124 (5%)

Query: 115  GPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSAL 174
            GP+   L+          +Q A K ++   Q+ ++QHLL +++  Q            AL
Sbjct: 3710 GPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQAL 3769

Query: 175  PPELPPTGILPTAS-----PSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQA 229
             P+  P G++P +S        L+P PP+     +      ++QQ     L  Q P  Q 
Sbjct: 3770 GPK--PQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQV 3827

Query: 230  FPTQ 233
              TQ
Sbjct: 3828 LMTQ 3831



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 50/195 (25%), Positives = 71/195 (36%), Gaps = 37/195 (18%)

Query: 46   NTGAWAPAEQFFPASNRTREGGGLWPPL-----PLQSSPAAPTMLDSSAAEQVTRLTLKL 100
            NTG   P       S +   G G+ P +      LQ   A    L   + +Q  +L   L
Sbjct: 4167 NTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALL 4226

Query: 101  LGQKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQ 160
            + ++L+Q +   +  P   + EPG +  P                    Q LL    +  
Sbjct: 4227 MQRQLQQSQAVRQTPP---YQEPGTQTSP-------------------LQGLLGCQPQLG 4264

Query: 161  AWSGPSRGALGSAL-------PPELP-PTGILPTASP-SPLAPDPPRIILPTVPQPPATI 211
             + GP  G L           PP LP P G L T     P+ P PP    P  P+ P+ +
Sbjct: 4265 GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSS-PQEPKRPSQL 4323

Query: 212  IQQLPQQPLIAQIPP 226
                 Q P  AQ+PP
Sbjct: 4324 PSPSSQLPTEAQLPP 4338



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 27/70 (38%), Positives = 33/70 (47%), Gaps = 15/70 (21%)

Query: 172  SALPPELPPTGILPTASPSPLAPDP------PRIILPTVP--QPPATIIQQLPQQPLIAQ 223
            SA PPE P      +  PSPLAP P      P + LPT P  +PP      L   P  A+
Sbjct: 4907 SAPPPEEP------SPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESAR 4960

Query: 224  IPPPQAFPTQ 233
             P P+A P +
Sbjct: 4961 -PKPRARPPE 4969



 Score = 29.3 bits (64), Expect = 4.9
 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 9/63 (14%)

Query: 175 PPELPPTGILPTASPSPLAPD-----PPRIILPTVPQPPAT-IIQQLPQQPLIAQIPPPQ 228
           PPE  P    P  SP+   P+     PP   LP  P P A  + + L + PL    PPP+
Sbjct: 443 PPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL---SPPPE 499

Query: 229 AFP 231
             P
Sbjct: 500 ESP 502


>gi|117938768 GNAS complex locus alex [Homo sapiens]
          Length = 626

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 79/331 (23%), Positives = 112/331 (33%), Gaps = 59/331 (17%)

Query: 43  PAGNTGAWAPAEQFFPASNRTREGGGLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLG 102
           P G+  A  P+ Q   +   +      W    L      P  L S   E     + +   
Sbjct: 62  PVGSMQALRPSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSYR--S 119

Query: 103 QKLEQERQNVEGGPEGLHLEPGNED----RPDDALQTALKRRRDLLQRLREQHL------ 152
           Q L QE Q ++G PE L   P         P++A  TAL  RR     L E+ L      
Sbjct: 120 QTLLQEAQVLQGSPELLPRSPKPSGLQRLAPEEA--TALPLRRLCHLSLMEKDLGTTAHP 177

Query: 153 --LDELSRAQAWSGPSRGALGSALPPELPPTGILPTASPSPLAPDPPRI--ILPT----- 203
               ELS     +  SR +        LPP   LP+ S +P A  P R+  +L T     
Sbjct: 178 RGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAA 237

Query: 204 ----VPQPPATI-IQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVL 258
                P P + +    L    L +    PQ+  T R     E  +     ++ Q+ +   
Sbjct: 238 PGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRR-KQ 296

Query: 259 QNWMLKALPPALQD---------PPHVPPRVPRAARP-------------RLPAVHHHH- 295
           Q W    +P   +          PP  P R+P   +P             ++P    H  
Sbjct: 297 QRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQP 356

Query: 296 ----HHHHAVWPPGAATVLQPAPSLWTPGPP 322
                H   +  PG     QP P   TPG P
Sbjct: 357 ILTPGHSQPIPTPGQPLPPQPIP---TPGRP 384


>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
          Length = 1164

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 57/248 (22%), Positives = 82/248 (33%), Gaps = 55/248 (22%)

Query: 37  PGGKARPAGNTGAWAPAEQFFPASNRTREGGGLWPPLPLQSSPAAPTMLDSSAAEQV--T 94
           P G A P G T +  PA    PAS+      GL   + L  + +     D+S+   +   
Sbjct: 382 PTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYKA 441

Query: 95  RLTLKLLGQKLEQERQNVEGGPEGLHLEPGNE--DRPD-----DALQTA----------- 136
           R    +   + E++    +G  E L     NE    PD     D+ +TA           
Sbjct: 442 RFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETAPAARTPQSPAP 501

Query: 137 ---LKRRRDLLQRLREQHLLDELSRAQAWSGPSRGA------------------------ 169
              L+ +R L    +E  +         W  P+R                          
Sbjct: 502 CVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLSIGDLDFSDLGEDEDQDMLNVE 561

Query: 170 ---LGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPP 226
               G  +P   PP  +L    P P  P PP I  P  P PP  +   LP       +P 
Sbjct: 562 SVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPH-----SVPD 616

Query: 227 PQAFPTQR 234
             A PT+R
Sbjct: 617 SSALPTKR 624


>gi|238859557 regulatory factor X1 [Homo sapiens]
          Length = 979

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 30/76 (39%), Positives = 33/76 (43%), Gaps = 6/76 (7%)

Query: 170 LGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQA 229
           L +A PP  PP    P A P P  P PP    P  PQPP       PQ     Q P PQA
Sbjct: 9   LQAAPPPSQPPQAP-PQAQPQPPPPPPPAA--PQPPQPPTAAATPQPQYVTELQSPQPQA 65

Query: 230 FPTQRSGSIKEDMVEL 245
            P    G  K+ + EL
Sbjct: 66  QP---PGGQKQYVTEL 78


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 54/169 (31%), Positives = 65/169 (38%), Gaps = 32/169 (18%)

Query: 172 SALPPELPPTGILPTA-SPSPL------APDPPRIILPTVPQPPATIIQQ--LPQQPLIA 222
           S  PP  PP   LP+A S S L       P PP   +P  P PPAT +Q   +P  P   
Sbjct: 321 SPTPPPPPPP--LPSALSTSSLRASMTSTPPPP---VPPPPPPPATALQAPAVPPPPAPL 375

Query: 223 QI--------PPPQAFP-TQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDP 273
           QI        PPP A P  Q S  +        + +   VH L      ++ LPP    P
Sbjct: 376 QIAPGVLHPAPPPIAPPLVQPSPPVARAAP---VCETVPVHPL--PQGEVQGLPP----P 426

Query: 274 PHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
           P  PP  P   RP  P       H  +   P  +T   P   L  P PP
Sbjct: 427 PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPP 475



 Score = 32.3 bits (72), Expect = 0.58
 Identities = 40/148 (27%), Positives = 48/148 (32%), Gaps = 38/148 (25%)

Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQR 234
           PP  PP      A P P        ++   PQ PAT   + P        PPP   P+  
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPAT--GRTPVFVSPTPPPPPPPLPSAL 335

Query: 235 SGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHH 294
           S S                         L+A   +   PP  PP  P A   + PAV   
Sbjct: 336 STS------------------------SLRASMTSTPPPPVPPPPPPPATALQAPAV--- 368

Query: 295 HHHHHAVWPPGAATVLQPAPSLWTPGPP 322
                   PP  A  LQ AP +  P PP
Sbjct: 369 --------PPPPAP-LQIAPGVLHPAPP 387


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 54/169 (31%), Positives = 65/169 (38%), Gaps = 32/169 (18%)

Query: 172 SALPPELPPTGILPTA-SPSPL------APDPPRIILPTVPQPPATIIQQ--LPQQPLIA 222
           S  PP  PP   LP+A S S L       P PP   +P  P PPAT +Q   +P  P   
Sbjct: 321 SPTPPPPPPP--LPSALSTSSLRASMTSTPPPP---VPPPPPPPATALQAPAVPPPPAPL 375

Query: 223 QI--------PPPQAFP-TQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDP 273
           QI        PPP A P  Q S  +        + +   VH L      ++ LPP    P
Sbjct: 376 QIAPGVLHPAPPPIAPPLVQPSPPVARAAP---VCETVPVHPL--PQGEVQGLPP----P 426

Query: 274 PHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
           P  PP  P   RP  P       H  +   P  +T   P   L  P PP
Sbjct: 427 PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPP 475



 Score = 32.3 bits (72), Expect = 0.58
 Identities = 40/148 (27%), Positives = 48/148 (32%), Gaps = 38/148 (25%)

Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQR 234
           PP  PP      A P P        ++   PQ PAT   + P        PPP   P+  
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPAT--GRTPVFVSPTPPPPPPPLPSAL 335

Query: 235 SGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHH 294
           S S                         L+A   +   PP  PP  P A   + PAV   
Sbjct: 336 STS------------------------SLRASMTSTPPPPVPPPPPPPATALQAPAV--- 368

Query: 295 HHHHHAVWPPGAATVLQPAPSLWTPGPP 322
                   PP  A  LQ AP +  P PP
Sbjct: 369 --------PPPPAP-LQIAPGVLHPAPP 387


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 54/169 (31%), Positives = 65/169 (38%), Gaps = 32/169 (18%)

Query: 172 SALPPELPPTGILPTA-SPSPL------APDPPRIILPTVPQPPATIIQQ--LPQQPLIA 222
           S  PP  PP   LP+A S S L       P PP   +P  P PPAT +Q   +P  P   
Sbjct: 321 SPTPPPPPPP--LPSALSTSSLRASMTSTPPPP---VPPPPPPPATALQAPAVPPPPAPL 375

Query: 223 QI--------PPPQAFP-TQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDP 273
           QI        PPP A P  Q S  +        + +   VH L      ++ LPP    P
Sbjct: 376 QIAPGVLHPAPPPIAPPLVQPSPPVARAAP---VCETVPVHPL--PQGEVQGLPP----P 426

Query: 274 PHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
           P  PP  P   RP  P       H  +   P  +T   P   L  P PP
Sbjct: 427 PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPP 475



 Score = 32.3 bits (72), Expect = 0.58
 Identities = 40/148 (27%), Positives = 48/148 (32%), Gaps = 38/148 (25%)

Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQR 234
           PP  PP      A P P        ++   PQ PAT   + P        PPP   P+  
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPAT--GRTPVFVSPTPPPPPPPLPSAL 335

Query: 235 SGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHH 294
           S S                         L+A   +   PP  PP  P A   + PAV   
Sbjct: 336 STS------------------------SLRASMTSTPPPPVPPPPPPPATALQAPAV--- 368

Query: 295 HHHHHAVWPPGAATVLQPAPSLWTPGPP 322
                   PP  A  LQ AP +  P PP
Sbjct: 369 --------PPPPAP-LQIAPGVLHPAPP 387


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 54/169 (31%), Positives = 65/169 (38%), Gaps = 32/169 (18%)

Query: 172 SALPPELPPTGILPTA-SPSPL------APDPPRIILPTVPQPPATIIQQ--LPQQPLIA 222
           S  PP  PP   LP+A S S L       P PP   +P  P PPAT +Q   +P  P   
Sbjct: 321 SPTPPPPPPP--LPSALSTSSLRASMTSTPPPP---VPPPPPPPATALQAPAVPPPPAPL 375

Query: 223 QI--------PPPQAFP-TQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDP 273
           QI        PPP A P  Q S  +        + +   VH L      ++ LPP    P
Sbjct: 376 QIAPGVLHPAPPPIAPPLVQPSPPVARAAP---VCETVPVHPL--PQGEVQGLPP----P 426

Query: 274 PHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
           P  PP  P   RP  P       H  +   P  +T   P   L  P PP
Sbjct: 427 PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPP 475



 Score = 32.3 bits (72), Expect = 0.58
 Identities = 40/148 (27%), Positives = 48/148 (32%), Gaps = 38/148 (25%)

Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQR 234
           PP  PP      A P P        ++   PQ PAT   + P        PPP   P+  
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPAT--GRTPVFVSPTPPPPPPPLPSAL 335

Query: 235 SGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHH 294
           S S                         L+A   +   PP  PP  P A   + PAV   
Sbjct: 336 STS------------------------SLRASMTSTPPPPVPPPPPPPATALQAPAV--- 368

Query: 295 HHHHHAVWPPGAATVLQPAPSLWTPGPP 322
                   PP  A  LQ AP +  P PP
Sbjct: 369 --------PPPPAP-LQIAPGVLHPAPP 387


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 46/150 (30%), Positives = 64/150 (42%), Gaps = 19/150 (12%)

Query: 174 LPPELPPTGILPTASPSPLAPDP---PRIILPTV--PQPPATIIQQLPQQPLIAQIPP-- 226
           LPP LP    LPTA+  P+ P     P +ILP++  P PPA+    LP Q +    PP  
Sbjct: 813 LPPALPD---LPTATVPPVPPPQYFSPAVILPSLAAPLPPAS--PALPLQAVKLPHPPGA 867

Query: 227 PQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARP 286
           P A P +         + LL +    V  L + + + +     L   P  P   P+ A  
Sbjct: 868 PLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQ-----LPGQPVYPAAFPQMAPT 922

Query: 287 RLPAVHHHHHHHHAVWPPGAATVLQPAPSL 316
            +P   HH   +    PP  A  L P P+L
Sbjct: 923 DVPPSPHHTVQNMRATPPQPA--LPPQPTL 950



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 36/121 (29%), Positives = 50/121 (41%), Gaps = 10/121 (8%)

Query: 176  PELPPTGILPTASPSPLAPD----PPRIILPTVP-QPPATIIQQLPQQPLIAQIPPPQAF 230
            P LPP    PT  P P+ P     PP+ +LP  P +PP  ++   P  P    +PP  A 
Sbjct: 942  PALPPQ---PTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPAL 998

Query: 231  PTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPA 290
            P  R   ++  + E          Q++L +    A+  A Q  P VP        P LP 
Sbjct: 999  PV-RPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQ-VPTVPVPPAAVLSPPLPE 1056

Query: 291  V 291
            V
Sbjct: 1057 V 1057



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 50/171 (29%), Positives = 60/171 (35%), Gaps = 46/171 (26%)

Query: 163 SGPSRGALGSALPP-ELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLI 221
           S P     G   PP + PP    PT  P  LAP P   ++P  P PP             
Sbjct: 714 STPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQP---VVPLQPVPPHL----------- 759

Query: 222 AQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVP 281
               PP   P  + G+  +       L+  Q+ Q  LQ   L  +PP +   P VPP  P
Sbjct: 760 ----PPYLAPASQVGAPAQ-------LKPLQMPQAPLQ--PLAQVPPQMPPIPVVPPITP 806

Query: 282 RA-------ARPRLPAVHHHHHHHHAVWPPGAATVLQPA---PSLWTPGPP 322
            A       A P LP           V P        PA   PSL  P PP
Sbjct: 807 LAGIDGLPPALPDLPTA--------TVPPVPPPQYFSPAVILPSLAAPLPP 849



 Score = 35.4 bits (80), Expect = 0.069
 Identities = 68/287 (23%), Positives = 98/287 (34%), Gaps = 45/287 (15%)

Query: 18   DRQKLPSPDSGHSLLCGWSPGGKAR------PAGNTGAWAPAEQFF----PASNRTREGG 67
            DR   P     H   CG   G ++R      P          +++F     A +   E  
Sbjct: 1268 DRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAP 1327

Query: 68   GLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLHLEPGNED 127
               PPLPL S P   +     +A    +L+ K     L  ++   + GP      P    
Sbjct: 1328 ESSPPLPLSSLPPEASQ---DSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPL 1384

Query: 128  RPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPP--TGILP 185
             P     TAL +                         P+ G    A  P  P   T  L 
Sbjct: 1385 APSSPPVTALPQD-------------GAAPATSTMPEPASGTASQAGGPGTPQGLTSELE 1431

Query: 186  TASP------SPLAPDPPRI-ILPTVPQPPATIIQQL--PQQPLIAQIPPPQAFPTQRSG 236
            T+ P      +PLA  P  + + P  P P A   +    P++PL    PPP   P+  SG
Sbjct: 1432 TSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPL----PPPAPEPSPHSG 1487

Query: 237  SIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRA 283
            + +  + +   L  A V  + L    L + P      P VPP+ P A
Sbjct: 1488 TPQPALGQPAPLLPAAVGAVSLATSQLPSPPLG----PTVPPQPPSA 1530



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 7/58 (12%)

Query: 174  LPPE--LPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQA 229
            LPP+  LPP  +LP     P+ P+P +  LP    P AT     P   ++   P P A
Sbjct: 980  LPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAAT-----PGSQILLGHPAPYA 1032



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 33/120 (27%), Positives = 46/120 (38%), Gaps = 21/120 (17%)

Query: 177  ELPPTGILPTA----SPSPLAPDPPRIIL---PTVPQPPATIIQQLPQQPLIAQIPPPQA 229
            +LP   + P A    +P+ + P P   +     T PQP       LP QP++   PP   
Sbjct: 905  QLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVL---PPQPT 961

Query: 230  FPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLP 289
             P Q           +L  Q  +  Q VL    +    P L   P +P R P   +P LP
Sbjct: 962  LPPQ----------PVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVR-PEPLQPHLP 1010


>gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
          Length = 931

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 46/189 (24%), Positives = 80/189 (42%), Gaps = 16/189 (8%)

Query: 109 RQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRG 168
           R  +EG  +   L+   +D+  +AL   L++++ L++RL+ Q  L++  RAQ    P+  
Sbjct: 515 RAELEGRDKDQMLQ--EKDKQIEALTRMLRQKQQLVERLKLQ--LEQEKRAQQ-PAPAPA 569

Query: 169 ALGSALPPELPPTGILPTASP-SPLAPDPPRIILPTV---------PQPPATIIQQLPQQ 218
            LG+ +  E   +    +  P  P  P  P +  P           P PP+ +++Q   Q
Sbjct: 570 PLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQ 629

Query: 219 PLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQD-PPHVP 277
           P    +P PQ     +  S+ + +    L+ ++    LVL      A  P L    P  P
Sbjct: 630 PEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQP 689

Query: 278 PRVPRAARP 286
              P +  P
Sbjct: 690 SSQPGSPAP 698


>gi|60460889 Myb protein P42POP [Homo sapiens]
          Length = 399

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 13/114 (11%)

Query: 176 PELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRS 235
           P LPP   L   +PSP +P PP       P+PP T+    P    +           + +
Sbjct: 225 PPLPPPPPLAQVAPSPPSPPPP-------PRPPPTLSASDPSLDFLRAQQETANAIRELA 277

Query: 236 GSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLP 289
           G++++ + +L    +A +   +L    + +LPP L  PP  PP      RP LP
Sbjct: 278 GTLRQGLAKLSEALSALLP--LLPGTPVDSLPPPLPPPPPPPP----PPRPVLP 325



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 1/46 (2%)

Query: 172 SALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQ 217
           SAL P LP T +     P P  P PP    P +P PPA  ++  P+
Sbjct: 292 SALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLP-PPAPKVEITPE 336


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 57/264 (21%), Positives = 110/264 (41%), Gaps = 37/264 (14%)

Query: 95    RLTLKLLGQKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKR-----RRDLLQRLRE 149
             RL L+++  ++E+  +  E      + E G     ++ ++    R     R + + R+ E
Sbjct: 10364 RLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIE 10423

Query: 150   QHLLDELSRAQAWSGPSRGALGSA--LPPELPPTGILPTASPSPLAPDPPRII------- 200
                 +E+   +    P +G   S   +PP+ PPT ++P   P    P+ P+ I       
Sbjct: 10424 VFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVR 10483

Query: 201   LPTVPQ-PPATIIQQLPQQPLIAQ----IPP---PQAFPTQRSGSIKEDMVELLL----- 247
             +P  P+ PP  + + LP + ++ +    +PP   P+A P +   + KE + E  +     
Sbjct: 10484 VPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPP 10543

Query: 248   ----LQNAQVHQL----VLQNWMLKALPPALQDPPHVPPRVPRAARP--RLPAVHHHHHH 297
                 +   +V ++    V +  + +A+PP  + PP   P  P+   P  ++PA       
Sbjct: 10544 KKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPE 10603

Query: 298   HHAVWPPGAATVLQPAPSLWTPGP 321
                V  P A   + P   +  P P
Sbjct: 10604 VTPVKVPEAPKEVVPEKKVPVPPP 10627



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 29/130 (22%), Positives = 53/130 (40%), Gaps = 15/130 (11%)

Query: 165   PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLI--A 222
             P +     A  PE+P   +       P  P+ P   +P VP+ P  ++++ P  P+   A
Sbjct: 10739 PKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKP--VLEEKPAVPVPERA 10796

Query: 223   QIPPPQAF-------PTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALP----PALQ 271
             + PPP+ +       P +     +E  V +   +  +V    +     K +P    P ++
Sbjct: 10797 ESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIK 10856

Query: 272   DPPHVPPRVP 281
              P   PP+ P
Sbjct: 10857 KPEAPPPKEP 10866


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 44/192 (22%), Positives = 75/192 (39%), Gaps = 22/192 (11%)

Query: 151 HLLDELSRAQAWSGPSRGALGSALPPELPPTGILPTASP----------SPLAPDPPRII 200
           H +  +++    + P    + + LPP+ PP  ++   +P          +  AP  P   
Sbjct: 750 HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPP 809

Query: 201 LPTVPQPPATIIQQLPQQPLIAQIP-PPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQ 259
           +P   + PA     +P  P    +P PP   P Q+S   K     L  + +  V + +  
Sbjct: 810 VPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPS--VVKQIAS 867

Query: 260 NWMLKALPPALQD------PPHVPPRVPRA--ARPR-LPAVHHHHHHHHAVWPPGAATVL 310
            +     PPA++       P +V P+ P A  A+P+  P+            PP ++ V 
Sbjct: 868 QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVF 927

Query: 311 QPAPSLWTPGPP 322
            P P    P PP
Sbjct: 928 PPPPPSPVPAPP 939



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 48/182 (26%), Positives = 62/182 (34%), Gaps = 45/182 (24%)

Query: 179 PPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQ---RS 235
           P T ++P  SP P    P     P+ P PP       P  P     PPP   P+Q    +
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPP---PPPPPPPPPPPPPPPPPLPSQSAPSA 657

Query: 236 GSIKEDMVE---LLLLQNAQVHQ---------LVLQNWMLK----------ALPPALQDP 273
           GS     V+   +  LQNA  H           V+Q+  +K            PP    P
Sbjct: 658 GSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPP 717

Query: 274 PHVP-------------PRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPG 320
           P  P             P +P+ + P  P   H   H   V PP       P P +  P 
Sbjct: 718 PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPP----TPPPPPPIPAPL 773

Query: 321 PP 322
           PP
Sbjct: 774 PP 775



 Score = 35.0 bits (79), Expect = 0.090
 Identities = 26/110 (23%), Positives = 39/110 (35%), Gaps = 32/110 (29%)

Query: 178 LPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGS 237
           +PP G++P   P P  P P   +    P P A      P  P  +  PPP          
Sbjct: 703 VPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA------PSLPQFSAPPPP---------- 746

Query: 238 IKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPR 287
                         ++HQ+     + +  PP    PP +P  +P  A P+
Sbjct: 747 -------------LKIHQV---QHITQVAPPTPPPPPPIPAPLPPQAPPK 780



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 15/158 (9%)

Query: 171 GSALPPELPPTGILPTASPSPLAPDPPRIILP--TVPQPPATI--IQQLPQ-QPLIAQIP 225
           G   PP  PP    P ++ + L P P    LP  + P PP  I  +Q + Q  P     P
Sbjct: 707 GVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP 766

Query: 226 PPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQ---NWMLKALPPALQDP----PHVPP 278
           PP   P       K  +          V  +V Q         +PPA + P     ++PP
Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP 826

Query: 279 RVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSL 316
             P    P  P          A  PP   + L P PS+
Sbjct: 827 SPPTPPVPVPPPTLPKQQSFCAKPPP---SPLSPVPSV 861



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 10/63 (15%)

Query: 176 PELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPT-QR 234
           P+  P+ I P  SP    P PP   L   P PP+ +    P  P     PPP A PT  +
Sbjct: 902 PKWQPSSI-PVPSPD-FPPPPPESSLVFPPPPPSPV--PAPPPP-----PPPTASPTPDK 952

Query: 235 SGS 237
           SGS
Sbjct: 953 SGS 955


>gi|21071077 dishevelled-associated activator of morphogenesis 1
           [Homo sapiens]
          Length = 1078

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 28/149 (18%)

Query: 103 QKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHL---------- 152
           +K+ +E   ++   E    E   + +  + +   L + ++ L++   +H           
Sbjct: 453 EKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLT 512

Query: 153 --LDELSR----AQAWSGPSRGALGSALPPELPPTGILPTASPSPLA----PDPPRIILP 202
             L ELSR    A    GPS GA G   P  +P + +LP   P PL     P PP  + P
Sbjct: 513 AQLHELSRRAVCASIPGGPSPGAPGGPFPSSVPGS-LLPPPPPPPLPGGMLPPPPPPLPP 571

Query: 203 TVPQPPATIIQQLPQQPLIAQIPPPQAFP 231
             P PP       P  P +  I PP   P
Sbjct: 572 GGPPPP-------PGPPPLGAIMPPPGAP 593


>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
          Length = 1488

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 56/198 (28%), Positives = 70/198 (35%), Gaps = 30/198 (15%)

Query: 152  LLDELSRAQAWSGPSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATI 211
            L D  S+ QA         G A PP LPP    P+  P P  P PP   L ++P PPA+ 
Sbjct: 1257 LPDGQSKLQALHAQYCQGPGPAPPPYLPPQQ--PSLPPPPQQP-PPLPQLGSIPPPPASA 1313

Query: 212  IQQLPQQPLIAQ--IPPPQAFPTQRSG-SIKEDMVELLLLQNAQVHQLVLQNWMLKALPP 268
                P +   A   +P PQ +   R G + +              H L      L    P
Sbjct: 1314 PPVGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSP 1373

Query: 269  ALQDPP------------HVPPRVPRAAR-----PRLPAVHHHHHHH-------HAVWPP 304
            A Q PP            H P  +P A        R P   + H HH       H+  PP
Sbjct: 1374 APQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPP 1433

Query: 305  GAATVLQPAPSLWTPGPP 322
              +    P PS  TP  P
Sbjct: 1434 HPSYPPLPPPSPHTPHSP 1451



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 27/103 (26%), Positives = 36/103 (34%), Gaps = 18/103 (17%)

Query: 213  QQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQD 272
            Q++P  P     PPP+ + +QR  S     +  L                 +   P    
Sbjct: 1178 QRMPPPP---PPPPPEEYKSQRPVSNSSSFLGSLFGSK-------------RGKGPFQMP 1221

Query: 273  PPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPS 315
            PP  P     A+     + HHHHHHHH     G   VL    S
Sbjct: 1222 PP--PTGQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQS 1262



 Score = 31.6 bits (70), Expect = 0.99
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 12/93 (12%)

Query: 165  PSRGALGSALPPELPPTGIL-----PTASPSPLAPDPPRIILPTVPQP-PATIIQQLPQQ 218
            P+ GA G   P   PP G       P +  SP +P PP    P +P P P T    LP  
Sbjct: 1398 PAAGAAGG--PGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPT 1455

Query: 219  ----PLIAQIPPPQAFPTQRSGSIKEDMVELLL 247
                PL A  PP  A P   +   K   +  ++
Sbjct: 1456 SPHGPLHASGPPGTANPPSANPKAKPSRISTVV 1488


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 37/117 (31%), Positives = 54/117 (46%), Gaps = 12/117 (10%)

Query: 117 EGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHL-LDELSRAQAWSGPSRGALGSALP 175
           E L L     D P +   +++ R ++L +  +   L L E S A A   P   A      
Sbjct: 335 EALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPPATSM--- 391

Query: 176 PEL---PPTGIL----PTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIP 225
           PEL   P T +L    P+A+P P  P P    +P +P PPAT + +LP  P +  +P
Sbjct: 392 PELQGPPVTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELP-GPSVTPVP 447



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 12/67 (17%)

Query: 172 SALP-PELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQ------PLIAQI 224
           SA P PELP     P ++P P  P PP   +P +P P  T + QL Q+      P +  +
Sbjct: 409 SATPVPELPG----PLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPAPSMG-L 463

Query: 225 PPPQAFP 231
            PPQ  P
Sbjct: 464 EPPQEVP 470



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 7/82 (8%)

Query: 165  PSRGALGSALPPELPPTG-ILPTASPSPLAPDPPRIILPT-VPQPPATIIQQLPQQPLI- 221
            P    +   LPPE PP G  LPT   +  A +      PT VP  P+      P+ P+  
Sbjct: 1162 PEEPPMTPPLPPEEPPEGPALPTEQSALTAEN----TWPTEVPSSPSEESVSQPEPPVSQ 1217

Query: 222  AQIPPPQAFPTQRSGSIKEDMV 243
            ++I  P A PT  S S  +  V
Sbjct: 1218 SEISEPSAVPTDYSVSASDPSV 1239


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 37/117 (31%), Positives = 54/117 (46%), Gaps = 12/117 (10%)

Query: 117 EGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHL-LDELSRAQAWSGPSRGALGSALP 175
           E L L     D P +   +++ R ++L +  +   L L E S A A   P   A      
Sbjct: 335 EALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPPATSM--- 391

Query: 176 PEL---PPTGIL----PTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIP 225
           PEL   P T +L    P+A+P P  P P    +P +P PPAT + +LP  P +  +P
Sbjct: 392 PELQGPPVTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELP-GPSVTPVP 447



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 12/67 (17%)

Query: 172 SALP-PELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQ------PLIAQI 224
           SA P PELP     P ++P P  P PP   +P +P P  T + QL Q+      P +  +
Sbjct: 409 SATPVPELPG----PLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPAPSMG-L 463

Query: 225 PPPQAFP 231
            PPQ  P
Sbjct: 464 EPPQEVP 470



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 7/82 (8%)

Query: 165  PSRGALGSALPPELPPTG-ILPTASPSPLAPDPPRIILPT-VPQPPATIIQQLPQQPLI- 221
            P    +   LPPE PP G  LPT   +  A +      PT VP  P+      P+ P+  
Sbjct: 1162 PEEPPMTPPLPPEEPPEGPALPTEQSALTAEN----TWPTEVPSSPSEESVSQPEPPVSQ 1217

Query: 222  AQIPPPQAFPTQRSGSIKEDMV 243
            ++I  P A PT  S S  +  V
Sbjct: 1218 SEISEPSAVPTDYSVSASDPSV 1239


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 47/179 (26%), Positives = 69/179 (38%), Gaps = 19/179 (10%)

Query: 66  GGGLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLH----L 121
           GG   PP P  S P   T+  + + E ++        Q    E     G P        L
Sbjct: 613 GGTRAPPQPSGSRPDTVTLRSAKSEESLS-------SQASGAELLGAGGAPASATPTPAL 665

Query: 122 EPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPPT 181
            PG   RP   +   L+     L    +Q +  +L  AQ   GP    + S LPP  PP 
Sbjct: 666 SPGRSLRPH-LIPLLLRGAEAPLTDACQQEMCSKLRGAQGPLGPD---MESPLPP--PPL 719

Query: 182 GIL-PTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIK 239
            +L P  +P P   +P R++   + +    + +Q  QQ      PP    P  RS S++
Sbjct: 720 SLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQSQQE-CGGTPPASQSPFHRSLSLE 777


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 61/254 (24%), Positives = 87/254 (34%), Gaps = 29/254 (11%)

Query: 25  PDSGHSLLCGWSPGGKARPAGNTGAWAPAEQFFPASNRTREGG-GLWPPLPLQSSPAAPT 83
           P+  +S + G SPGG  RP       +P     P+S  + + G    PP  L   PA+P 
Sbjct: 552 PNPANSWVPGLSPGGSRRPPR-----SPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPG 606

Query: 84  MLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDL 143
                  E+VT  +L+  G  +     ++         +P   DR    + T L  R  +
Sbjct: 607 KAQPPKPERVT--SLRSPGASVSSSLTSLCSSSS----DPAPSDRSGPQILTPLGDRFVI 660

Query: 144 LQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPT 203
               +                P+  AL  A P  +P  G + T   SP +P  P+  L  
Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPAL--AAPAVVP--GPVSTTDASPQSPPTPQTTLTP 716

Query: 204 VPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWML 263
           + + P     Q P        PPP   P        E +VE           L   NW  
Sbjct: 717 LQESPVISKDQSPPPS-----PPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNW-- 769

Query: 264 KALPPALQDPPHVP 277
              PP    PP  P
Sbjct: 770 ---PP---PPPPAP 777



 Score = 32.7 bits (73), Expect = 0.44
 Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 18/119 (15%)

Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQ------ 228
           PP   P  ++   S S  A +P +      P PPA   Q L     +A  PPP+      
Sbjct: 742 PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLS----MADFPPPEEAFFSV 797

Query: 229 AFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPR-VPRAARP 286
           A P     S   ++V      ++    L +Q       PP   DPP  PP   P ++ P
Sbjct: 798 ASPEPAGPSGSPELVSSPAASSSSATALQIQ-------PPGSPDPPPAPPAPAPASSAP 849



 Score = 32.0 bits (71), Expect = 0.76
 Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 22/129 (17%)

Query: 165 PSRGALGSALPPELPPTGIL-PTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQ 223
           PS G    +  P LPP G+  P ASP    P  P  +  ++  P A++   L      + 
Sbjct: 580 PSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVT-SLRSPGASVSSSLTSLCSSSS 638

Query: 224 IPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALP--PALQDPPHVPPRVP 281
            P P    + RSG               Q+   +   +++   P  PA   PP   PR P
Sbjct: 639 DPAP----SDRSGP--------------QILTPLGDRFVIPPHPKVPAPFSPPPSKPRSP 680

Query: 282 RAARPRLPA 290
             A P L A
Sbjct: 681 NPAAPALAA 689


>gi|40288197 GATA binding protein 6 [Homo sapiens]
          Length = 595

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 18/39 (46%), Positives = 19/39 (48%)

Query: 283 AARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGP 321
           AARP     HHHHHHHH    P +  V  P    W  GP
Sbjct: 315 AARPLNGTYHHHHHHHHHHPSPYSPYVGAPLTPAWPAGP 353


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 50/227 (22%), Positives = 92/227 (40%), Gaps = 19/227 (8%)

Query: 91  EQVTRLTLKLLGQKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQ 150
           +Q+ R+    L Q+ +Q++Q  +   + L  +P  +  P    Q    +   L Q+L++ 
Sbjct: 236 QQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA--LPQQLQQM 293

Query: 151 HLLDELSRAQAWSGPSRGALGSALPPELPPTG-ILPTASPSPLAPDPPRIILPTVPQPPA 209
           H        Q    P +  +    P +LPP     P  S +   P     +L T  QPP 
Sbjct: 294 H---HTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQ---MLYT--QPPL 345

Query: 210 TIIQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPA 269
             ++     P++ Q PP Q    Q+  +++      ++    QV Q  L   ML +  P 
Sbjct: 346 KFVRA----PMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLP--MLSSPSPG 399

Query: 270 --LQDPPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAP 314
             +Q P  +PP    + +P  P+   + +      P  ++ +  P+P
Sbjct: 400 QQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSP 446



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 33/108 (30%), Positives = 40/108 (37%), Gaps = 1/108 (0%)

Query: 213 QQLPQQPLIAQIPPPQAFPTQRSGSIKE-DMVELLLLQNAQVHQLVLQNWMLKALPPALQ 271
           QQ  QQ LI      Q    Q+   ++    ++L   Q  Q  Q   Q   L+A PP  Q
Sbjct: 213 QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ 272

Query: 272 DPPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTP 319
            P   P   P  A P+     HH  HH     P    V Q  PS   P
Sbjct: 273 PPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPP 320


>gi|32307177 forkhead box G1 [Homo sapiens]
          Length = 489

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 16/31 (51%), Positives = 16/31 (51%)

Query: 292 HHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
           HHHHHHHH   PP  A    P P    P PP
Sbjct: 47  HHHHHHHHHHHPPPPAPQPPPPPQQQQPPPP 77



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 19/52 (36%), Positives = 21/52 (40%), Gaps = 3/52 (5%)

Query: 179 PPTGILPTASPSPLAPDPPRIILPTVPQP---PATIIQQLPQQPLIAQIPPP 227
           PP    P   P    P PP    P  PQ    PA    + PQQ L+   PPP
Sbjct: 59  PPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPP 110


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 76/297 (25%), Positives = 101/297 (34%), Gaps = 52/297 (17%)

Query: 36   SPGGKARPAGNTGAWAPAEQFFPASNRTREGG-------GLWPPL--PLQSSPAAPTMLD 86
            SPG      G  G    A++      R   GG       GL  PL   L      P M  
Sbjct: 2047 SPGATRLARGGLGEGEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLESLGGRARDPRMAR 2106

Query: 87   SSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDLLQR 146
            ++++E        L  + L++     +G  E      G   R    L+  + R     +R
Sbjct: 2107 AASSEAAPHHQPPLENRGLQKSSSFSQGEAE----PRGRHRRAGAPLEIPVARLG--ARR 2160

Query: 147  LREQHLLDELSRAQAWSGPSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQ 206
            L+E   L  LS AQ  S     A   + P    P+   P+ +P P AP P +      P+
Sbjct: 2161 LQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQ---DKAPE 2217

Query: 207  P-PATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKA 265
            P P  +    P        PPPQA  T          + L L   AQ+ Q +        
Sbjct: 2218 PRPEPVRASKP-------APPPQALQT----------LALPLTPYAQIIQSL-------Q 2253

Query: 266  LPPALQDPPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
            L    Q P   P     AA P  P  H       A  PPGA     P+      GPP
Sbjct: 2254 LSGHAQGPSQGP-----AAPPSEPKPHAAVFARVASPPPGAPEKRVPSAG----GPP 2301



 Score = 31.6 bits (70), Expect = 0.99
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 10/66 (15%)

Query: 173  ALPPELPPTGILPTASPSPLAPDPPRIIL--PTVPQPPATIIQQLPQQPLIAQIPPPQAF 230
            A PP+  PT + P  +P+  AP PP + +   + P PP+  +  L      A  PPPQ  
Sbjct: 2794 ARPPD-SPTSLAPPLAPA--APTPPSVTVSPSSPPTPPSQALSSLK-----AVGPPPQTP 2845

Query: 231  PTQRSG 236
            P +  G
Sbjct: 2846 PRRHRG 2851


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,169,659
Number of Sequences: 37866
Number of extensions: 1163182
Number of successful extensions: 12502
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 235
Number of HSP's successfully gapped in prelim test: 636
Number of HSP's that attempted gapping in prelim test: 7759
Number of HSP's gapped (non-prelim): 3696
length of query: 322
length of database: 18,247,518
effective HSP length: 102
effective length of query: 220
effective length of database: 14,385,186
effective search space: 3164740920
effective search space used: 3164740920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.