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Search of human proteins with 40018640
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40018640 parafibromin [Homo sapiens]
(531 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40018640 parafibromin [Homo sapiens] 1061 0.0
gi|55741677 SET domain containing 1A [Homo sapiens] 40 0.005
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 39 0.012
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 39 0.012
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 37 0.059
gi|46852390 coiled-coil domain containing 6 [Homo sapiens] 37 0.059
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 36 0.077
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 36 0.100
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 36 0.100
gi|194353989 sodium channel, nonvoltage-gated 1, delta isoform 1... 35 0.13
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 35 0.22
gi|42794779 myosin 18A isoform b [Homo sapiens] 35 0.22
gi|28416946 myosin 18A isoform a [Homo sapiens] 35 0.22
gi|34101282 sodium channel, nonvoltage-gated 1, delta isoform 2 ... 34 0.29
gi|156104874 envoplakin [Homo sapiens] 34 0.38
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 33 0.65
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 33 0.65
gi|4507447 transcription factor AP-4 (activating enhancer bindin... 33 0.85
gi|226246554 hypothetical protein LOC643677 [Homo sapiens] 32 1.4
gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sap... 32 1.4
gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sap... 32 1.4
gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sap... 32 1.4
gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens] 32 1.4
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 32 1.4
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 32 1.9
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 32 1.9
gi|116875765 tight junction protein 1 isoform b [Homo sapiens] 31 2.5
gi|116875767 tight junction protein 1 isoform a [Homo sapiens] 31 2.5
gi|219555736 zinc finger protein 438 isoform b [Homo sapiens] 31 2.5
gi|219555734 zinc finger protein 438 isoform b [Homo sapiens] 31 2.5
>gi|40018640 parafibromin [Homo sapiens]
Length = 531
Score = 1061 bits (2743), Expect = 0.0
Identities = 531/531 (100%), Positives = 531/531 (100%)
Query: 1 MADVLSVLRQYNIQKKEIVVKGDEVIFGEFSWPKNVKTNYVVWGTGKEGQPREYYTLDSI 60
MADVLSVLRQYNIQKKEIVVKGDEVIFGEFSWPKNVKTNYVVWGTGKEGQPREYYTLDSI
Sbjct: 1 MADVLSVLRQYNIQKKEIVVKGDEVIFGEFSWPKNVKTNYVVWGTGKEGQPREYYTLDSI 60
Query: 61 LFLLNNVHLSHPVYVRRAATENIPVVRRPDRKDLLGYLNGEASTSASIDRSAPLEIGLQR 120
LFLLNNVHLSHPVYVRRAATENIPVVRRPDRKDLLGYLNGEASTSASIDRSAPLEIGLQR
Sbjct: 61 LFLLNNVHLSHPVYVRRAATENIPVVRRPDRKDLLGYLNGEASTSASIDRSAPLEIGLQR 120
Query: 121 STQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVE 180
STQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVE
Sbjct: 121 STQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVE 180
Query: 181 KIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTILQS 240
KIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTILQS
Sbjct: 181 KIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTILQS 240
Query: 241 TGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKG 300
TGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKG
Sbjct: 241 TGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKG 300
Query: 301 KEETEGFKIDTMGTYHGMTLKSVTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTP 360
KEETEGFKIDTMGTYHGMTLKSVTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTP
Sbjct: 301 KEETEGFKIDTMGTYHGMTLKSVTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTP 360
Query: 361 IIIIPAATTSLITMLNAKDLLQDLKFVPSDEKKKQGCQRENETLIQRRKDQMQPGGTAIS 420
IIIIPAATTSLITMLNAKDLLQDLKFVPSDEKKKQGCQRENETLIQRRKDQMQPGGTAIS
Sbjct: 361 IIIIPAATTSLITMLNAKDLLQDLKFVPSDEKKKQGCQRENETLIQRRKDQMQPGGTAIS 420
Query: 421 VTVPYRVVDQPLKLMPQDWDRVVAVFVQGPAWQFKGWPWLLPDGSPVDIFAKIKAFHLKY 480
VTVPYRVVDQPLKLMPQDWDRVVAVFVQGPAWQFKGWPWLLPDGSPVDIFAKIKAFHLKY
Sbjct: 421 VTVPYRVVDQPLKLMPQDWDRVVAVFVQGPAWQFKGWPWLLPDGSPVDIFAKIKAFHLKY 480
Query: 481 DEVRLDPNVQKWDVTVLELSYHKRHLDRPVFLRFWETLDRYMVKHKSHLRF 531
DEVRLDPNVQKWDVTVLELSYHKRHLDRPVFLRFWETLDRYMVKHKSHLRF
Sbjct: 481 DEVRLDPNVQKWDVTVLELSYHKRHLDRPVFLRFWETLDRYMVKHKSHLRF 531
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 40.0 bits (92), Expect = 0.005
Identities = 70/336 (20%), Positives = 124/336 (36%), Gaps = 31/336 (9%)
Query: 101 EASTSASIDRSAPLEIGLQRSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGH 160
EAS S P E Q K A + K P+ ++E K R + L+
Sbjct: 905 EASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSE 964
Query: 161 -KEGIVQTEQIRSLSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVD 219
+E ++ + + E+ + + K+ T +D +D+ + + + A+ D
Sbjct: 965 GEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSD 1024
Query: 220 VTRDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQRPA--PNAAPVD 277
D S + ++ S+ + S + + S ++ E E+RPA P+A+P
Sbjct: 1025 GENDSTSDSE---SSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASP-- 1079
Query: 278 PTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTEGASARKTQTPAA 337
P P PA ER G T + + + A R + PA
Sbjct: 1080 PPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAG 1139
Query: 338 QPVPRPVSQARP-------PPNQKKG---SRTPIIIIPAATTSLITMLNAKDLLQDLKFV 387
P P P RP PP +K+ S + I ++PA T AK
Sbjct: 1140 PPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFP------G 1193
Query: 388 PSDEKKKQGCQR-------ENETLIQRRKDQMQPGG 416
P+ K +G +R ++ +L++ +++ GG
Sbjct: 1194 PASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGG 1229
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 38.9 bits (89), Expect = 0.012
Identities = 47/207 (22%), Positives = 88/207 (42%), Gaps = 30/207 (14%)
Query: 118 LQRSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIV-QTEQIRSLSEA 176
LQ+ +V R + KK IED + R +K++ L+ K+ + Q E +R++ E
Sbjct: 127 LQQMAEVTREGFRL----KKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEE 182
Query: 177 MSV--------------EKIAAIKAKIMAKKRSTIKTDLDDD------ITALKQRSFVDA 216
E++AA KA+ + + +LDDD +T L+ +D
Sbjct: 183 AEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDT 242
Query: 217 EVDVTRDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPV 276
+ D + + T Q+ +F ++A ++ K R E P PAP+A +
Sbjct: 243 DGDGALSEAEAQALLSGDT---QTDATSFYDRVWAAIRD-KYRSEA-LPTDLPAPSAPDL 297
Query: 277 DPTLRTKQPIPAAYNRYDQERFKGKEE 303
+ P+P++ ++E + +EE
Sbjct: 298 TEPKEEQPPVPSSPTEEEEEEEEEEEE 324
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 38.9 bits (89), Expect = 0.012
Identities = 47/207 (22%), Positives = 88/207 (42%), Gaps = 30/207 (14%)
Query: 118 LQRSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIV-QTEQIRSLSEA 176
LQ+ +V R + KK IED + R +K++ L+ K+ + Q E +R++ E
Sbjct: 127 LQQMAEVTREGFRL----KKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEE 182
Query: 177 MSV--------------EKIAAIKAKIMAKKRSTIKTDLDDD------ITALKQRSFVDA 216
E++AA KA+ + + +LDDD +T L+ +D
Sbjct: 183 AEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDT 242
Query: 217 EVDVTRDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPV 276
+ D + + T Q+ +F ++A ++ K R E P PAP+A +
Sbjct: 243 DGDGALSEAEAQALLSGDT---QTDATSFYDRVWAAIRD-KYRSEA-LPTDLPAPSAPDL 297
Query: 277 DPTLRTKQPIPAAYNRYDQERFKGKEE 303
+ P+P++ ++E + +EE
Sbjct: 298 TEPKEEQPPVPSSPTEEEEEEEEEEEE 324
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 36.6 bits (83), Expect = 0.059
Identities = 39/167 (23%), Positives = 61/167 (36%), Gaps = 24/167 (14%)
Query: 261 EGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTL 320
EG P PN P +P + P+ Y Q++ + + ++ G + T GT G
Sbjct: 1297 EGNMSTGAPQPNLMPSNPD--SGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPF 1354
Query: 321 KSVTEGASARKTQTPAAQPVPRPVSQARPPPN----------QKKGSRTPIIIIPAATTS 370
S ++ Q + P+PRP+ P QK G P I A
Sbjct: 1355 PSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAP-- 1412
Query: 371 LITMLNAKDLLQDLKFVPSDEKKKQGCQRENETLIQRRKDQMQPGGT 417
+ + +D+ F P + Q L QRR+ M+ GT
Sbjct: 1413 ----VQPPMIRRDITFPPGSVEATQ------PVLKQRRRLTMKDIGT 1449
>gi|46852390 coiled-coil domain containing 6 [Homo sapiens]
Length = 474
Score = 36.6 bits (83), Expect = 0.059
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 2/65 (3%)
Query: 306 GFKIDTMGTYHGMTLKSVTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTPIIIIP 365
G + MGT HG+T S S K + P P P + +PPP P +P
Sbjct: 397 GLHVQHMGTSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQP--TVP 454
Query: 366 AATTS 370
+A TS
Sbjct: 455 SAATS 459
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 36.2 bits (82), Expect = 0.077
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Query: 96 GYLNGEASTSASIDRSAPLEIGLQRSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLAA 155
G + GE+ S ++ A E Q + + DE+ A+A+K ++ E RL KE A
Sbjct: 713 GPIPGESLASGVAEQEALREEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQA 772
Query: 156 R---LEGHKEGIVQTEQIRSLSEAM 177
R E H+E Q + L EA+
Sbjct: 773 RRAEAEAHREAEAQAWEQARLREAV 797
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 35.8 bits (81), Expect = 0.100
Identities = 39/161 (24%), Positives = 68/161 (42%), Gaps = 10/161 (6%)
Query: 81 ENIPVVRRPDRKDLLGYLNGEASTSASIDRSAPLEIGLQRSTQVKRAA-DEVLAEAKKPR 139
E + + + +DL L GE S +D L + R +V +A DE+L++ K
Sbjct: 966 EELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVAN 1025
Query: 140 IEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVEKIAAI----KAKIMAKKRS 195
E D+E L R + I+ EQ + + E +++ I + + KK
Sbjct: 1026 FATME----DEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQ 1081
Query: 196 TIKTDLDDDITALKQRSFV-DAEVDVTRDIVSRERVWRTRT 235
T +D D + QRS ++E + + D +R R R+
Sbjct: 1082 TNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRS 1122
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 35.8 bits (81), Expect = 0.100
Identities = 24/104 (23%), Positives = 42/104 (40%), Gaps = 9/104 (8%)
Query: 263 RAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKS 322
R P PAP A + R +P PA R + + + + S
Sbjct: 2578 RVPSPTPAPKEAVREG--RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635
Query: 323 VTEGASARKTQT------PAAQPVPRPVSQARPPPNQKKGSRTP 360
+ +S+ + + P Q +P+P S +PPP +++ SR+P
Sbjct: 2636 SSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR-SRSP 2678
Score = 35.0 bits (79), Expect = 0.17
Identities = 46/196 (23%), Positives = 82/196 (41%), Gaps = 22/196 (11%)
Query: 171 RSLSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERV 230
RS SE+ SV++ + + + RS +LD +A Q +E D + D ++
Sbjct: 1516 RSGSES-SVDQKTVARTPLGQRSRSGSSQELDVKPSASPQER---SESDSSPDSKAK--- 1568
Query: 231 WRTRTTILQSTGKNFSKNIFAILQ-SVKAREEGRAPEQRPAPNAAP-----VDPTLRTKQ 284
TRT + Q + S + + + S + G +PE + P AAP D + K
Sbjct: 1569 --TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKA 1626
Query: 285 PIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTEGASARKTQTPAAQPVPRPV 344
P P A R R + ++G G+ + +S E +T ++ P P
Sbjct: 1627 PAPRALPR----RSRSGSSSKGRGPSPEGS---SSTESSPEHPPKSRTARRGSRSSPEPK 1679
Query: 345 SQARPPPNQKKGSRTP 360
+++R PP ++ +P
Sbjct: 1680 TKSRTPPRRRSSRSSP 1695
>gi|194353989 sodium channel, nonvoltage-gated 1, delta isoform 1
[Homo sapiens]
Length = 704
Score = 35.4 bits (80), Expect = 0.13
Identities = 18/50 (36%), Positives = 28/50 (56%)
Query: 324 TEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTPIIIIPAATTSLIT 373
T+ +A K AAQ PRP + PPP K+G + ++ +PA+ L+T
Sbjct: 78 TQHNAACKQGQAAAQTPPRPGPPSAPPPPPKEGHQEGLVELPASFRELLT 127
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 34.7 bits (78), Expect = 0.22
Identities = 29/112 (25%), Positives = 44/112 (39%), Gaps = 15/112 (13%)
Query: 257 KAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYH 316
K R G+ PE P A ++P+ T QP+ + +G+ K
Sbjct: 1396 KNRSSGKTPETL-VPTAPKLEPSTSTDQPVTPEPT---SQATRGRTNRSSVK-------- 1443
Query: 317 GMTLKSVTEGASARKTQTPAAQPV-PRPVSQARPPPNQKKGSRTPIIIIPAA 367
T ++V A + T QPV P P SQA + +TP ++P A
Sbjct: 1444 --TPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTA 1493
Score = 31.6 bits (70), Expect = 1.9
Identities = 30/110 (27%), Positives = 41/110 (37%), Gaps = 12/110 (10%)
Query: 264 APEQRPAPNAAPVDPTLRT-----KQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGM 318
AP +P + PT+R Q P A + E F K + K M +
Sbjct: 1062 APPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPF--- 1118
Query: 319 TLKSVTEGASARKTQTPAAQPV-PRPVSQARPPPNQKKGSRTPIIIIPAA 367
T A T AQPV P+P SQA + +TP ++P A
Sbjct: 1119 ---PATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTA 1165
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 34.7 bits (78), Expect = 0.22
Identities = 33/193 (17%), Positives = 83/193 (43%), Gaps = 4/193 (2%)
Query: 114 LEIGLQRSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQ-TEQIRS 172
L + + + K A +E L+ ++ + E + + D+E + ++ HK + Q + +
Sbjct: 1716 LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQ 1775
Query: 173 LSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWR 232
+++ + + A + + + +K +++ ++ ++ +S V + R++ +R R
Sbjct: 1776 INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFER 1835
Query: 233 TRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNR 292
T+ L+S +N+ + + R++ A E R + LR + R
Sbjct: 1836 TQVKRLESLASRLKENMEKLTEE---RDQRIAAENREKEQNKRLQRQLRDTKEEMGELAR 1892
Query: 293 YDQERFKGKEETE 305
+ E + K E E
Sbjct: 1893 KEAEASRKKHELE 1905
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 34.7 bits (78), Expect = 0.22
Identities = 33/193 (17%), Positives = 83/193 (43%), Gaps = 4/193 (2%)
Query: 114 LEIGLQRSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQ-TEQIRS 172
L + + + K A +E L+ ++ + E + + D+E + ++ HK + Q + +
Sbjct: 1716 LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQ 1775
Query: 173 LSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWR 232
+++ + + A + + + +K +++ ++ ++ +S V + R++ +R R
Sbjct: 1776 INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFER 1835
Query: 233 TRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNR 292
T+ L+S +N+ + + R++ A E R + LR + R
Sbjct: 1836 TQVKRLESLASRLKENMEKLTEE---RDQRIAAENREKEQNKRLQRQLRDTKEEMGELAR 1892
Query: 293 YDQERFKGKEETE 305
+ E + K E E
Sbjct: 1893 KEAEASRKKHELE 1905
>gi|34101282 sodium channel, nonvoltage-gated 1, delta isoform 2
[Homo sapiens]
Length = 638
Score = 34.3 bits (77), Expect = 0.29
Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 3/54 (5%)
Query: 320 LKSVTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTPIIIIPAATTSLIT 373
+++ T G S + AAQ PRP + PPP K+G + ++ +PA+ L+T
Sbjct: 11 MEAATRGGSHLQA---AAQTPPRPGPPSAPPPPPKEGHQEGLVELPASFRELLT 61
>gi|156104874 envoplakin [Homo sapiens]
Length = 2033
Score = 33.9 bits (76), Expect = 0.38
Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 20/147 (13%)
Query: 108 IDRSAPLEIGLQRS-TQVKRAADEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQ 166
IDR+ L R ++++RA D+ D+EC RL +E A + ++ +
Sbjct: 1564 IDRAETLGRTWSREESELQRARDQA----------DQECGRLQQELRALERQKQQQTLQL 1613
Query: 167 TEQIRSLSEAMSVEK-IAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIV 225
E+ + LS+ E+ AA + + +++ + I + D K+R+ D V+R+ +
Sbjct: 1614 QEESKLLSQKTESERQKAAQRGQELSRLEAAILREKDQIYE--KERTLRDLHAKVSREEL 1671
Query: 226 SRERVWR-----TRTTILQ-STGKNFS 246
S+E R T+ +IL+ TGK+ S
Sbjct: 1672 SQETQTRETNLSTKISILEPETGKDMS 1698
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 33.1 bits (74), Expect = 0.65
Identities = 42/178 (23%), Positives = 63/178 (35%), Gaps = 34/178 (19%)
Query: 242 GKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDP------TLRTKQPIPAAYNRYDQ 295
G + + IL++ A E R P P P+A P D + T +P A +
Sbjct: 2262 GMETDEAVSGILETEAATESSRPPVNAPDPSAGPTDTKEARGNSSETSHSVPEAKGSKEV 2321
Query: 296 E-----RFKGKEETEGFKIDTMGTYHGMTLKSVTEGASARKTQTPAAQ---PVPRPVSQA 347
E + KG+++T T T K V + ++ AQ P +
Sbjct: 2322 EVTLVRKDKGRQKT------TRSRRKRNTNKKVVAPVESHVPESNQAQGESPAANEGTTV 2375
Query: 348 RPP--PNQKKGSRTPIIIIPAATTSLITMLNAKDLLQDLKFVPSDEKKKQGCQRENET 403
+ P P ++K S P P + TS DL +PS E Q E T
Sbjct: 2376 QHPEAPQEEKQSEKPHSTPPQSCTS------------DLSKIPSTENSSQEISVEERT 2421
Score = 29.3 bits (64), Expect = 9.4
Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 12/121 (9%)
Query: 260 EEGRAPEQRPAPNAAPVDPTLRTKQ------PIPAAYNRYDQERFKGKEETEGFKIDTMG 313
EEG + +Q P +A P P Q P P + + K +E E K +
Sbjct: 1720 EEGSSGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPLSKPAQKSEEANEP-KAEKPD 1778
Query: 314 TYHGMTLKSVTEGASARKTQTPAAQP--VPRPVSQARPPPNQKKGSRTPIIIIPAATTSL 371
+ + +A ++Q PA++ V PV+ PN+ K S+TP + AA S+
Sbjct: 1779 ATADAEPDANQKAEAAPESQPPASEDLEVDPPVAAKDKKPNKSKRSKTP---VQAAAVSI 1835
Query: 372 I 372
+
Sbjct: 1836 V 1836
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 33.1 bits (74), Expect = 0.65
Identities = 51/221 (23%), Positives = 87/221 (39%), Gaps = 24/221 (10%)
Query: 209 KQRSFVDAEVDVTRDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSVKAREEGRAPE-- 266
K++ + E + + ++RER + R ++ S S + + L S K++ +P
Sbjct: 415 KEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASEL-SPKSKARPSSPSTS 473
Query: 267 -QRPAPNAAPVDP--TLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSV 323
RPA P TL K P P + R + KEE + + G KS
Sbjct: 474 WHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAK-----ESPSAAGPEDKSQ 528
Query: 324 TEG-ASARKTQTPAAQPVPRPVSQARPPPNQKK--GSRTP----IIIIPAATTSLIT--- 373
++ AS K A P P P P P QK+ + TP ++ P A +T
Sbjct: 529 SKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSK 588
Query: 374 -MLNAKDLLQDLKFVPSDEK--KKQGCQRENETLIQRRKDQ 411
M D + + + + ++Q + E E +Q +D+
Sbjct: 589 PMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDK 629
>gi|4507447 transcription factor AP-4 (activating enhancer binding
protein 4) [Homo sapiens]
Length = 338
Score = 32.7 bits (73), Expect = 0.85
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 17/94 (18%)
Query: 118 LQRSTQVKRAADEVLAEAKKPRI--------------EDEECVRLDKERLAARLEGHKEG 163
LQ++TQ+KR E+ + K R EDE+ L +E + R + KE
Sbjct: 107 LQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKER 166
Query: 164 IVQT---EQIRSLSEAMSVEKIAAIKAKIMAKKR 194
V+ EQ+RSL M EK+ I ++ +++
Sbjct: 167 SVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQ 200
>gi|226246554 hypothetical protein LOC643677 [Homo sapiens]
Length = 7081
Score = 32.0 bits (71), Expect = 1.4
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 13/118 (11%)
Query: 233 TRTTILQ-------STGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQP 285
T TTI Q S K + + I S A ++ + P+++ NA +D + K+
Sbjct: 845 TYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKK- 903
Query: 286 IPAAYNRYDQERFKGKEETEGFK----IDTMGTYHGMTLKSVTEGASARKTQTPAAQP 339
P +R +QE+ E T+GF+ + Y ++ ++ G+S + QP
Sbjct: 904 -PQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQP 960
>gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo
sapiens]
Length = 6929
Score = 32.0 bits (71), Expect = 1.4
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 13/118 (11%)
Query: 233 TRTTILQ-------STGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQP 285
T TTI Q S K + + I S A ++ + P+++ NA +D + K+
Sbjct: 774 TYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKK- 832
Query: 286 IPAAYNRYDQERFKGKEETEGFK----IDTMGTYHGMTLKSVTEGASARKTQTPAAQP 339
P +R +QE+ E T+GF+ + Y ++ ++ G+S + QP
Sbjct: 833 -PQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQP 889
>gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo
sapiens]
Length = 6929
Score = 32.0 bits (71), Expect = 1.4
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 13/118 (11%)
Query: 233 TRTTILQ-------STGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQP 285
T TTI Q S K + + I S A ++ + P+++ NA +D + K+
Sbjct: 774 TYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKK- 832
Query: 286 IPAAYNRYDQERFKGKEETEGFK----IDTMGTYHGMTLKSVTEGASARKTQTPAAQP 339
P +R +QE+ E T+GF+ + Y ++ ++ G+S + QP
Sbjct: 833 -PQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQP 889
>gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo
sapiens]
Length = 6929
Score = 32.0 bits (71), Expect = 1.4
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 13/118 (11%)
Query: 233 TRTTILQ-------STGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQP 285
T TTI Q S K + + I S A ++ + P+++ NA +D + K+
Sbjct: 774 TYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKK- 832
Query: 286 IPAAYNRYDQERFKGKEETEGFK----IDTMGTYHGMTLKSVTEGASARKTQTPAAQP 339
P +R +QE+ E T+GF+ + Y ++ ++ G+S + QP
Sbjct: 833 -PQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQP 889
>gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens]
Length = 529
Score = 32.0 bits (71), Expect = 1.4
Identities = 33/156 (21%), Positives = 62/156 (39%), Gaps = 12/156 (7%)
Query: 129 DEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVEKIAAIKAK 188
D A + R + E +R ++R ++ G + + +TE+ SE + +
Sbjct: 378 DSSSAMGVENRAKLEARLRTLEDRGIRKISGTGKALAKTEKYEHKSEVKTYDPSGDSTLP 437
Query: 189 IMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTILQSTGKNFSKN 248
+KKR + D +D+IT K + A++ V + E+V T ++ K K
Sbjct: 438 TCSKKRKIEQVDKEDEITEKKAKK---AKIKVKVEEEEEEKVAEEEETSVKKKKKRGKK- 493
Query: 249 IFAILQSVKAREEGRAPEQRPAPNAAPVDPTLRTKQ 284
K +E E+ P + A P + K+
Sbjct: 494 --------KHIKEEPLSEEEPCTSTAIASPEKKKKK 521
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 32.0 bits (71), Expect = 1.4
Identities = 61/253 (24%), Positives = 96/253 (37%), Gaps = 36/253 (14%)
Query: 120 RSTQVKRAADEVLAEAKKPRIEDEECVRLDKERLA------ARLEGHKEGI------VQT 167
++T+ K D V KKP I ++ERLA +G K GI + +
Sbjct: 10 QATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKDGLKAGIEAGNINITS 69
Query: 168 EQIRSLSEAMSVEKIAAIKAKIMAKKRS-TIKTDLDDD-----ITALKQRSFVDAEVDVT 221
++ + E +S E+ A + A+ +KR+ I DD + AL + + E
Sbjct: 70 GEVFEIEEHIS-ERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAE 128
Query: 222 RDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQRPAPNAAPVDPTLR 281
R R + T L+ T K+ K S K++EE + PN+ V
Sbjct: 129 RRERLRNILSVVGTDALKKTKKDDEK-------SKKSKEEYQQTWYHEGPNSLKVARLWI 181
Query: 282 TKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTEGASARKTQTPAAQPVP 341
+P A R ++ R KE E + M H +L+S+ S
Sbjct: 182 ANYSLPRAMKRLEEARLH-KEIPETTRTSQMQELH-KSLRSLNNFCSQIGDD-------- 231
Query: 342 RPVSQARPPPNQK 354
RP+S PN K
Sbjct: 232 RPISYCHFSPNSK 244
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 31.6 bits (70), Expect = 1.9
Identities = 19/81 (23%), Positives = 34/81 (41%), Gaps = 1/81 (1%)
Query: 302 EETEGFKIDTMGTYHGMTLKS-VTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTP 360
E G + +T G H + + T + +PA + VPRP + RP P +
Sbjct: 2397 ERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPA 2456
Query: 361 IIIIPAATTSLITMLNAKDLL 381
++ +P + I+ N +L
Sbjct: 2457 LVPVPVSAPVPISAPNPITIL 2477
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 31.6 bits (70), Expect = 1.9
Identities = 41/193 (21%), Positives = 82/193 (42%), Gaps = 32/193 (16%)
Query: 105 SASIDRSAPLEIGLQRSTQVKRAADEVLAEAKK--PRIEDEECVRLDKERLAA----RLE 158
SAS R+ L+ LQR + E L +AKK +++ E V D+++L LE
Sbjct: 1225 SASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELE 1284
Query: 159 GHK-----EGIVQTEQIRSLSEAMSVEKIAA-------------IKAKIMAKKRSTIKTD 200
K E ++ I+ L E ++ +K+ +K KI+ R T++
Sbjct: 1285 KKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLE-- 1342
Query: 201 LDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTIL-----QSTGKNFSKNIFAILQS 255
+ + T ++Q ++A+++ + + W+ + L Q + K N + +
Sbjct: 1343 -EQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKL 1401
Query: 256 VKAREEGRAPEQR 268
++E + EQ+
Sbjct: 1402 TNLQDELQESEQK 1414
>gi|116875765 tight junction protein 1 isoform b [Homo sapiens]
Length = 1668
Score = 31.2 bits (69), Expect = 2.5
Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 267 QRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTEG 326
Q+ P+ APV+ T +T++ + AYNR+ + + K ++ H + L S T
Sbjct: 1421 QKSFPDKAPVNGTEQTQKTVTPAYNRFTPKPYTSSARPFERKFESPKFNHNL-LPSETAH 1479
Query: 327 ASARKTQTPAA-QPVPRPVSQARPP 350
++TP + + + + S A+PP
Sbjct: 1480 KPDLSSKTPTSPKTLVKSHSLAQPP 1504
>gi|116875767 tight junction protein 1 isoform a [Homo sapiens]
Length = 1748
Score = 31.2 bits (69), Expect = 2.5
Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 267 QRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTEG 326
Q+ P+ APV+ T +T++ + AYNR+ + + K ++ H + L S T
Sbjct: 1501 QKSFPDKAPVNGTEQTQKTVTPAYNRFTPKPYTSSARPFERKFESPKFNHNL-LPSETAH 1559
Query: 327 ASARKTQTPAA-QPVPRPVSQARPP 350
++TP + + + + S A+PP
Sbjct: 1560 KPDLSSKTPTSPKTLVKSHSLAQPP 1584
>gi|219555736 zinc finger protein 438 isoform b [Homo sapiens]
Length = 818
Score = 31.2 bits (69), Expect = 2.5
Identities = 15/58 (25%), Positives = 27/58 (46%)
Query: 313 GTYHGMTLKSVTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTPIIIIPAATTS 370
GT+ + L V +K + + + P+ + +PP N K + PI+I P + S
Sbjct: 80 GTFSLVALPHVASAQPIQKPRMSLPENLKLPIPRYQPPRNSKASRKKPILIFPKSGCS 137
>gi|219555734 zinc finger protein 438 isoform b [Homo sapiens]
Length = 818
Score = 31.2 bits (69), Expect = 2.5
Identities = 15/58 (25%), Positives = 27/58 (46%)
Query: 313 GTYHGMTLKSVTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTPIIIIPAATTS 370
GT+ + L V +K + + + P+ + +PP N K + PI+I P + S
Sbjct: 80 GTFSLVALPHVASAQPIQKPRMSLPENLKLPIPRYQPPRNSKASRKKPILIFPKSGCS 137
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,158,972
Number of Sequences: 37866
Number of extensions: 962044
Number of successful extensions: 5127
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 4981
Number of HSP's gapped (non-prelim): 247
length of query: 531
length of database: 18,247,518
effective HSP length: 107
effective length of query: 424
effective length of database: 14,195,856
effective search space: 6019042944
effective search space used: 6019042944
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.