Guide to the Human Genome
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Search of human proteins with 39777614

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|39777614 SS18-like protein 1 [Homo sapiens]
         (396 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|39777614 SS18-like protein 1 [Homo sapiens]                        811   0.0  
gi|56117846 synovial sarcoma translocation, chromosome 18 isofor...   485   e-137
gi|56117844 synovial sarcoma translocation, chromosome 18 isofor...   417   e-117
gi|10047104 synovial sarcoma translocation gene on chromosome 18...    94   3e-19
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     67   4e-11
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     67   4e-11
gi|62122917 filaggrin family member 2 [Homo sapiens]                   66   6e-11
gi|57864582 hornerin [Homo sapiens]                                    65   8e-11
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]          65   1e-10
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho...    63   5e-10
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom...    63   5e-10
gi|171916097 repetin [Homo sapiens]                                    63   5e-10
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]           60   3e-09
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    59   8e-09
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    59   8e-09
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    59   8e-09
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s...    55   1e-07
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...    55   1e-07
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    55   1e-07
gi|93141033 PAX interacting protein 1 [Homo sapiens]                   54   2e-07
gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]           54   2e-07
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]           54   2e-07
gi|60097902 filaggrin [Homo sapiens]                                   54   3e-07
gi|33286444 mastermind-like 2 [Homo sapiens]                           52   7e-07
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s...    52   1e-06
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...    52   1e-06
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap...    52   1e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    52   1e-06
gi|110347429 mediator complex subunit 12 [Homo sapiens]                50   4e-06
gi|57165375 glutamate receptor, ionotropic, N-methyl D-aspartate...    49   6e-06

>gi|39777614 SS18-like protein 1 [Homo sapiens]
          Length = 396

 Score =  811 bits (2096), Expect = 0.0
 Identities = 396/396 (100%), Positives = 396/396 (100%)

Query: 1   MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY 60
           MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY
Sbjct: 1   MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY 60

Query: 61  LATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ 120
           LATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ
Sbjct: 61  LATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ 120

Query: 121 GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180
           GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN
Sbjct: 121 GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180

Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240
           MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ
Sbjct: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240

Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300
           GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ
Sbjct: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300

Query: 301 HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360
           HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ
Sbjct: 301 HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360

Query: 361 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
           GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ
Sbjct: 361 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396


>gi|56117846 synovial sarcoma translocation, chromosome 18 isoform 1
           [Homo sapiens]
          Length = 418

 Score =  485 bits (1248), Expect = e-137
 Identities = 251/419 (59%), Positives = 293/419 (69%), Gaps = 24/419 (5%)

Query: 1   MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY 60
           MSVAFA+ R RGKGE+T   IQKMLD+N+HLIQCI++ Q+KGKT+EC+QYQQ+LH NLVY
Sbjct: 1   MSVAFAAPRQRGKGEITPAAIQKMLDDNNHLIQCIMDSQNKGKTSECSQYQQMLHTNLVY 60

Query: 61  LATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ 120
           LATIADSNQNMQSLLPAPPTQNM +GPG + QSG      S    SD +  G PP+  +Q
Sbjct: 61  LATIADSNQNMQSLLPAPPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQ 120

Query: 121 GQIGN---GPSHVSMQQTAPNTLPTTSMSISGP--------GYSHAGPASQGVPMQGQGT 169
            Q+     GP+H+ MQ   PN L  T+ S++ P        GY+H+ P+SQ +P+Q Q T
Sbjct: 121 NQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGYNHSVPSSQSMPVQNQMT 180

Query: 170 ------IGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQS-SIAMMGQGSQ 222
                 +GNY  R N++MQ N   MM QQ  +  Y+  QGG QHYQGQ   + MMGQ +Q
Sbjct: 181 MSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGMMGQVNQ 240

Query: 223 GSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSH-SQGAAEPMGQQYYPDGHGDYAY 281
           G+ MMGQR + PYRP QQG  QQY GQE+YYG+QYSH  QG  E M QQYYPDGH DY Y
Sbjct: 241 GNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPDGHNDYGY 300

Query: 282 QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTY--SQQQYPSQQSYP 339
           QQ SY EQ YDR +E+S+QHYYEGGNSQY QQQ  Y QG   QQ Y   QQQYP QQ YP
Sbjct: 301 QQPSYPEQGYDRPYEDSSQHYYEGGNSQYGQQQDAY-QGPPPQQGYPPQQQQYPGQQGYP 359

Query: 340 GQQQGYGSAQGAPS-QYPGYQQGQGQQYGSYRAPQTA-PSAQQQRPYGYEQGQYGNYQQ 396
           GQQQGYG +QG P  QYP Y QGQGQQYG YR  Q   P   QQRPYGY+QGQYGNYQQ
Sbjct: 360 GQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRPYGYDQGQYGNYQQ 418


>gi|56117844 synovial sarcoma translocation, chromosome 18 isoform 2
           [Homo sapiens]
          Length = 387

 Score =  417 bits (1073), Expect = e-117
 Identities = 229/419 (54%), Positives = 268/419 (63%), Gaps = 55/419 (13%)

Query: 1   MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY 60
           MSVAFA+ R RGKGE+T   IQKMLD+N+HLIQCI++ Q+KGKT+EC+QYQQ+LH NLVY
Sbjct: 1   MSVAFAAPRQRGKGEITPAAIQKMLDDNNHLIQCIMDSQNKGKTSECSQYQQMLHTNLVY 60

Query: 61  LATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ 120
           LATIADSNQNMQSLLPAPPTQNM +GPG + QSG      S    SD +  G PP+  +Q
Sbjct: 61  LATIADSNQNMQSLLPAPPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQ 120

Query: 121 GQIGN---GPSHVSMQQTAPNTLPTTSMSISGP--------GYSHAGPASQGVPMQGQGT 169
            Q+     GP+H+ MQ   PN L  T+ S++ P        GY+H+ P+SQ +P+Q Q T
Sbjct: 121 NQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGYNHSVPSSQSMPVQNQMT 180

Query: 170 I------GNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSS-IAMMGQGSQ 222
           +      GNY  R N++MQ N   MM QQ  +  Y+  QGG QHYQGQ   + MMGQ +Q
Sbjct: 181 MSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGMMGQVNQ 240

Query: 223 GSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHS-QGAAEPMGQQYYPDGHGDYAY 281
           G+ MMGQR + PYRP QQG  QQY GQE+YYG+QYSH  QG  E M QQYYPD       
Sbjct: 241 GNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPD------- 293

Query: 282 QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTY--SQQQYPSQQSYP 339
                                   GNSQY QQQ  YQ G   QQ Y   QQQYP QQ YP
Sbjct: 294 ------------------------GNSQYGQQQDAYQ-GPPPQQGYPPQQQQYPGQQGYP 328

Query: 340 GQQQGYGSAQGAPS-QYPGYQQGQGQQYGSYRAPQTAP-SAQQQRPYGYEQGQYGNYQQ 396
           GQQQGYG +QG P  QYP Y QGQGQQYG YR  Q  P    QQRPYGY+QGQYGNYQQ
Sbjct: 329 GQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRPYGYDQGQYGNYQQ 387


>gi|10047104 synovial sarcoma translocation gene on chromosome
          18-like 2 [Homo sapiens]
          Length = 77

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 44/73 (60%), Positives = 56/73 (76%)

Query: 1  MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY 60
          MSVAF     RGK EV Q+TIQ++L+EN  LI+CI+EYQ+KG+  EC QYQ +LHRNL+Y
Sbjct: 1  MSVAFVPDWLRGKAEVNQETIQRLLEENDQLIRCIVEYQNKGRGNECVQYQHVLHRNLIY 60

Query: 61 LATIADSNQNMQS 73
          LATIAD++    S
Sbjct: 61 LATIADASPTSTS 73


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 81/282 (28%), Positives = 106/282 (37%), Gaps = 31/282 (10%)

Query: 121 GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGY--SHAGPASQGVPMQGQGTIGNYVSRTN 178
           G  G GP+ ++ Q          + + SG     SH  P S G      G  G  ++RT 
Sbjct: 323 GGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPG----SSGGGGQPLARTP 378

Query: 179 INMQSNPVSMMQQQAATSHYSSAQGGSQHY---QGQSSIAMMGQGSQGSSMMGQRPMAPY 235
               S+P+  M +     +     GG+  Y   QG  S    G G  G     Q P   Y
Sbjct: 379 --QPSSPMDQMGKMRPQPY-----GGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQR-Y 430

Query: 236 RPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSF 295
             + QG +Q  +G   Y  +   + Q      GQQ    G   Y  QQS + +Q      
Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQ----GQTPYYNQQSPHPQQQQPPYS 486

Query: 296 EESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQ--QYPSQQS---YPGQQQGYGSAQG 350
           ++          S   Q Q+   Q  + Q  YSQQ  Q P QQS   YP QQ    + Q 
Sbjct: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQS---TTQQ 543

Query: 351 APSQYPGYQQGQGQQ-YGSYRAPQTAPSA-QQQRPYGYEQGQ 390
            P   P Y Q Q Q  Y   +  Q APS   QQ  Y   Q Q
Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQ 585



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 82/358 (22%), Positives = 125/358 (34%), Gaps = 54/358 (15%)

Query: 65   ADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIG 124
            ADS ++   + P  P  + ++  G  T   +S  +   G L        P S +      
Sbjct: 1121 ADSKKSQPKIQPPSPAGSGSM-QGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGM 1179

Query: 125  NGPSHVSMQQT----APNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180
            +  + V +Q      + +T    +     PGY    P+     M G         R +  
Sbjct: 1180 SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQ---PSMNTSDMMG---------RMSYE 1227

Query: 181  MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240
               +P   M++   +  + S+  G     G       G G  G+  MG R   PY     
Sbjct: 1228 PNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGL-GNVAMGPRQHYPY----- 1281

Query: 241  GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGH----GDYAYQQSSYTEQSYDRSFE 296
            G     +  E   G + + S GA +P      PD        Y  QQ    +Q +D    
Sbjct: 1282 GGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGN 1341

Query: 297  ESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQY----PSQQSYPGQQQG--YGSAQG 350
            + +      G+   SQQ   YQQ   QQQ Y +       P  + + G+     Y + QG
Sbjct: 1342 QFSTQGTPSGSPFPSQQTTMYQQ---QQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQG 1398

Query: 351  APSQY-----------------PGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391
             P Q                  P  QQ    QYG+   P TA +A ++RP G  Q Q+
Sbjct: 1399 QPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGN-AYPATATAATERRPAGGPQNQF 1455



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 63/265 (23%), Positives = 87/265 (32%), Gaps = 73/265 (27%)

Query: 72  QSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGL--PPSSLLQGQIGN---- 125
           Q+  P    Q     P  L+Q  +     SQ S   A S     PP  L Q   G+    
Sbjct: 555 QAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASS 614

Query: 126 GPSHVSMQ----------QTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVS 175
            PS  S +          Q+ P++LP  S SI              +PM  +G +   VS
Sbjct: 615 APSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD------------LPMGTEGALSPGVS 662

Query: 176 RTNINM----QSNPVSMMQQQAATSHYSSAQGGSQHYQGQ-SSIAMMGQGSQGSSMMGQR 230
            + I+     QSNP         + H    +G S    G  +S+A    G    + +   
Sbjct: 663 TSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN 722

Query: 231 PMAPYRPSQQGSS-------QQYLGQEEYYGE------QYS------------------- 258
            M P  PS Q  S       Q  + Q+  Y +      QYS                   
Sbjct: 723 QMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIH 782

Query: 259 --------HSQGAAEPMGQQYYPDG 275
                   +S G+  P G QY P G
Sbjct: 783 TGMGSYQQNSMGSYGPQGGQYGPQG 807


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 81/282 (28%), Positives = 106/282 (37%), Gaps = 31/282 (10%)

Query: 121 GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGY--SHAGPASQGVPMQGQGTIGNYVSRTN 178
           G  G GP+ ++ Q          + + SG     SH  P S G      G  G  ++RT 
Sbjct: 323 GGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPG----SSGGGGQPLARTP 378

Query: 179 INMQSNPVSMMQQQAATSHYSSAQGGSQHY---QGQSSIAMMGQGSQGSSMMGQRPMAPY 235
               S+P+  M +     +     GG+  Y   QG  S    G G  G     Q P   Y
Sbjct: 379 --QPSSPMDQMGKMRPQPY-----GGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQR-Y 430

Query: 236 RPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSF 295
             + QG +Q  +G   Y  +   + Q      GQQ    G   Y  QQS + +Q      
Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQ----GQTPYYNQQSPHPQQQQPPYS 486

Query: 296 EESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQ--QYPSQQS---YPGQQQGYGSAQG 350
           ++          S   Q Q+   Q  + Q  YSQQ  Q P QQS   YP QQ    + Q 
Sbjct: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQS---TTQQ 543

Query: 351 APSQYPGYQQGQGQQ-YGSYRAPQTAPSA-QQQRPYGYEQGQ 390
            P   P Y Q Q Q  Y   +  Q APS   QQ  Y   Q Q
Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQ 585



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 63/265 (23%), Positives = 87/265 (32%), Gaps = 73/265 (27%)

Query: 72  QSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGL--PPSSLLQGQIGN---- 125
           Q+  P    Q     P  L+Q  +     SQ S   A S     PP  L Q   G+    
Sbjct: 555 QAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASS 614

Query: 126 GPSHVSMQ----------QTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVS 175
            PS  S +          Q+ P++LP  S SI              +PM  +G +   VS
Sbjct: 615 APSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD------------LPMGTEGALSPGVS 662

Query: 176 RTNINM----QSNPVSMMQQQAATSHYSSAQGGSQHYQGQ-SSIAMMGQGSQGSSMMGQR 230
            + I+     QSNP         + H    +G S    G  +S+A    G    + +   
Sbjct: 663 TSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN 722

Query: 231 PMAPYRPSQQGSS-------QQYLGQEEYYGE------QYS------------------- 258
            M P  PS Q  S       Q  + Q+  Y +      QYS                   
Sbjct: 723 QMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIH 782

Query: 259 --------HSQGAAEPMGQQYYPDG 275
                   +S G+  P G QY P G
Sbjct: 783 TGMGSYQQNSMGSYGPQGGQYGPQG 807



 Score = 33.9 bits (76), Expect = 0.26
 Identities = 66/322 (20%), Positives = 101/322 (31%), Gaps = 65/322 (20%)

Query: 65   ADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIG 124
            ADS ++   + P  P  + ++  G  T   +S  +   G L        P S +      
Sbjct: 1121 ADSKKSQPKIQPPSPAGSGSM-QGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGM 1179

Query: 125  NGPSHVSMQQT----APNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180
            +  + V +Q      + +T    +     PGY    P+     M G         R +  
Sbjct: 1180 SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQ---PSMNTSDMMG---------RMSYE 1227

Query: 181  MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240
               +P   M++   +  + S+  G     G       G G  G+  MG R   PY     
Sbjct: 1228 PNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGL-GNVAMGPRQHYPY----- 1281

Query: 241  GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300
            G     +  E   G + + S GA +P      PD  G Y+                    
Sbjct: 1282 GGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDS-GMYS-------------------- 1320

Query: 301  HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360
                   S+Y  QQ              QQQ     SY  Q    G+  G+P  +P  Q 
Sbjct: 1321 ------PSRYPPQQ-------------QQQQQQRHDSYGNQFSTQGTPSGSP--FPSQQT 1359

Query: 361  GQGQQYGSYRAPQTAPSAQQQR 382
               QQ     +P   P   + R
Sbjct: 1360 TMYQQQQQVSSPAPLPRPMENR 1381



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 24/102 (23%), Positives = 34/102 (33%), Gaps = 9/102 (8%)

Query: 293  RSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAP 352
            RS     Q  +  G+    Q++         Q + +      + SY   +  YGS + AP
Sbjct: 1181 RSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAP 1240

Query: 353  SQYP------GYQQGQGQQYGSYRAP---QTAPSAQQQRPYG 385
               P      G   G G  Y     P     A   +Q  PYG
Sbjct: 1241 GSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG 1282


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 86/309 (27%), Positives = 112/309 (36%), Gaps = 28/309 (9%)

Query: 93  SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQ-QTAPNTLPTTSMSISGPG 151
           SG S G    GS S   S+G        GQ      H S   Q++     + S   SG G
Sbjct: 574 SGQSTGFGQYGSGSGQ-SSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYG 632

Query: 152 YSHAGPASQGVPMQGQGT-----IGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQ 206
             H    + G    G G+      G Y S       S   S   Q  + S  SS  G  +
Sbjct: 633 -QHGSRQTSGFGQHGSGSSQSTGFGQYGSG------SGQSSGFGQHVSGSGQSSGFGQHE 685

Query: 207 HYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEP 266
              G SS    G GS  SS  GQ   +  + S  G  +   GQ   +G+   H  G+ + 
Sbjct: 686 SRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQ---HGSGSGQS 742

Query: 267 MGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY-QQGAAQQQ 325
            G   +  G G     QSS   Q   RS + S      G +S  S Q +GY Q G+ Q  
Sbjct: 743 SGFGQHGSGSG-----QSSGFGQHESRSGQSSY-----GQHSSGSSQSSGYGQHGSRQTS 792

Query: 326 TYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYG 385
            + Q    S QS    Q G GS Q A     G   GQ   +G + +     S  Q     
Sbjct: 793 GFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGS 852

Query: 386 YEQGQYGNY 394
            +   YG +
Sbjct: 853 SQSSGYGQH 861



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 89/331 (26%), Positives = 124/331 (37%), Gaps = 50/331 (15%)

Query: 81  QNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ----GQIGNGPSHVSMQQTA 136
           Q+   G        SS G HS GS     S+G       Q    GQ G+G S        
Sbjct: 602 QSSGFGQHESRSGQSSYGQHSSGSSQ---SSGYGQHGSRQTSGFGQHGSGSSQ------- 651

Query: 137 PNTLPTTSMSISGPGYSHAGPASQGVPMQGQGT-IGNYVSRTNINMQ------SNPVSMM 189
                +T     G G   +    Q V   GQ +  G + SR+  +        S+  S  
Sbjct: 652 -----STGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGY 706

Query: 190 QQQAATSHYSSAQGGSQHYQGQSS-IAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLG 248
            Q  ++S  +S  G  +   GQSS     G GS  SS  GQ      + S  G  +   G
Sbjct: 707 GQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSG 766

Query: 249 QEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNS 308
           Q  Y      HS G+++         G+G +  +Q+S   Q    S + +    Y  G  
Sbjct: 767 QSSY----GQHSSGSSQ-------SSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSG-- 813

Query: 309 QYSQQQAGYQQ---GAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ 365
             S Q AG+ Q   G+ Q   + Q +  S QS  G Q G GS+Q +     G   GQ   
Sbjct: 814 --SGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYG-QHGSGSSQSSGYGQHGSSSGQTSG 870

Query: 366 YGSYRAPQTAPSAQQQRPYGYEQ----GQYG 392
           +G +R+     S   Q   G  Q    GQ+G
Sbjct: 871 FGQHRSSSGQYSGFGQHGSGSGQSSGFGQHG 901



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 84/309 (27%), Positives = 119/309 (38%), Gaps = 37/309 (11%)

Query: 101 SQGSLSDAISTGLPPSSLLQGQI-GNGPSHVSMQQTAPNTLP-----TTSMSISGPGYSH 154
           SQ +  +   TGL  SS  +  + G+G +    + T+  +L      ++S   SG G   
Sbjct: 424 SQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHG 483

Query: 155 AGPASQ---GVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQ 211
           +G       G    G G    +    +++ QS   S   Q  + S  SS  G  +    Q
Sbjct: 484 SGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQS---SGFGQHGSVSGQSSGFGQHESRSRQ 540

Query: 212 SSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYG-EQYSHSQGAAEPMGQQ 270
           SS    G GS  SS  GQ           G  Q  LG  +  G  QY    G +   GQ 
Sbjct: 541 SSYGQHGSGSSQSSGYGQYGSR----ETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQ- 595

Query: 271 YYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY-QQGAAQQQTYSQ 329
                HG  + Q S + +         S Q  Y G +S  S Q +GY Q G+ Q   + Q
Sbjct: 596 -----HGSGSGQSSGFGQHE-----SRSGQSSY-GQHSSGSSQSSGYGQHGSRQTSGFGQ 644

Query: 330 QQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYG-SYRAPQTAPSAQQQRPYGYEQ 388
               S QS    Q  YGS  G  S +  +  G GQ  G      ++  S+  Q  +G  Q
Sbjct: 645 HGSGSSQSTGFGQ--YGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQ 702

Query: 389 ----GQYGN 393
               GQ+G+
Sbjct: 703 SSGYGQHGS 711



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 74/286 (25%), Positives = 96/286 (33%), Gaps = 22/286 (7%)

Query: 93   SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGY 152
            SG S G    GS S   S+G        G+      H S + +  N     S S    GY
Sbjct: 955  SGQSSGFGQHGSGSGQ-SSGFGQHESGSGKSSGFGQHES-RSSQSNYGQHGSGSSQSSGY 1012

Query: 153  SHAGPASQGVPMQGQ--GTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG 210
               G +S      GQ   + G Y         S+  S   Q    S  SS  G  +    
Sbjct: 1013 GQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSR 1072

Query: 211  QSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQ 270
            QSS    G GS  SS  GQ      + S  G  +   GQ   +G QY    G +   GQ 
Sbjct: 1073 QSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFG-QYGSGSGQSSGFGQ- 1130

Query: 271  YYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQ 330
                 HG    + S + +  Y        QH   G  S  S     ++ G+    ++ Q 
Sbjct: 1131 -----HGSGTGKSSGFAQHEYRSGQSSYGQH---GTGSSQSSGCGQHESGSGPTTSFGQH 1182

Query: 331  QYPSQQ--------SYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGS 368
               S          S  GQ  G+G       Q  G  QG+ QQ  S
Sbjct: 1183 VSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVES 1228



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 89/339 (26%), Positives = 116/339 (34%), Gaps = 46/339 (13%)

Query: 93   SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAP-NTLPTTSMSISGPG 151
            SG S G     S S   S G   S   Q   G G    S  QT+      ++S   SG G
Sbjct: 827  SGQSSGFGQHESRSHQSSYGQHGSGSSQSS-GYGQHGSSSGQTSGFGQHRSSSGQYSGFG 885

Query: 152  YSHAGPA-SQGVPMQGQGT-----IGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGS 205
               +G   S G    G G+      G + SR++ +      S   Q +    + S+ G +
Sbjct: 886  QHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQT 945

Query: 206  ----QHYQGQ---SSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEY------ 252
                QH  G    S     G GS  SS  GQ      + S  G  +    Q  Y      
Sbjct: 946  FGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSG 1005

Query: 253  ------YGEQYSHSQGAAEPMGQ------QYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300
                  YG Q+  S G     GQ      QY   G       QSS   Q    S + S  
Sbjct: 1006 SSQSSGYG-QHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGF 1064

Query: 301  HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360
              YE  + Q S  Q G   G++Q   Y Q       S  GQ  G+G  +    Q  G+ Q
Sbjct: 1065 GQYESRSRQSSYGQHG--SGSSQSSGYGQ-----HGSNSGQTSGFGQHRPGSGQSSGFGQ 1117

Query: 361  -----GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNY 394
                 GQ   +G + +     S   Q  Y   Q  YG +
Sbjct: 1118 YGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQH 1156



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 75/306 (24%), Positives = 103/306 (33%), Gaps = 39/306 (12%)

Query: 95   SSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQ-QTAPNTLPTTSMSISGPGYS 153
            SS G H  GS     S+G        GQ      H S   Q++     + S   SG G  
Sbjct: 730  SSFGQHGSGS---GQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYG-Q 785

Query: 154  HAGPASQGVPMQGQGT-----IGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208
            H    + G    G G+      G Y S       S   +   Q  + S  SS  G  +  
Sbjct: 786  HGSRQTSGFGQHGSGSSQSTGFGQYGSG------SGQSAGFGQHGSGSGQSSGFGQHESR 839

Query: 209  QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMG 268
              QSS    G GS  SS  GQ   +  + S  G  +   GQ   +G+   H  G+ +  G
Sbjct: 840  SHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQ---HGSGSGQSSG 896

Query: 269  QQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYS 328
               +  G G Y+                   QH      S Y Q    +  G++Q   Y 
Sbjct: 897  FGQHGTGSGQYS----------------GFGQHESRSHQSSYGQ----HGSGSSQSSGYG 936

Query: 329  QQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQ 388
            Q    S Q++   Q   GS Q +     G   GQ   +G + +     S   Q      Q
Sbjct: 937  QHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQ 996

Query: 389  GQYGNY 394
              YG +
Sbjct: 997  SNYGQH 1002



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 83/312 (26%), Positives = 110/312 (35%), Gaps = 28/312 (8%)

Query: 93   SGSSQ--GLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGP 150
            SGSSQ  G    GS S   S G        GQ      H S    +      +  S S  
Sbjct: 799  SGSSQSTGFGQYGSGSGQ-SAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSS- 856

Query: 151  GYSHAGPASQGVPMQGQ--GTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208
            GY   G +S      GQ   + G Y         S   S   Q    S   S  G  +  
Sbjct: 857  GYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESR 916

Query: 209  QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMG 268
              QSS    G GS  SS  GQ   +  +    G  +   GQ   +G+   H  G+ +  G
Sbjct: 917  SHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQ---HGSGSGQSSG 973

Query: 269  QQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY-QQGAAQQQTY 327
               +  G G     +SS   Q   RS   S  +Y + G+   S Q +GY Q G++  QT 
Sbjct: 974  FGQHESGSG-----KSSGFGQHESRS---SQSNYGQHGSG--SSQSSGYGQHGSSSGQTT 1023

Query: 328  SQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ-----GQGQQYGSYRAPQTAPSAQQQR 382
               Q+ S     GQ  G+G       Q  G+ Q     GQ   +G Y +     S  Q  
Sbjct: 1024 GFGQHRSSS---GQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHG 1080

Query: 383  PYGYEQGQYGNY 394
                +   YG +
Sbjct: 1081 SGSSQSSGYGQH 1092



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 63/277 (22%), Positives = 97/277 (35%), Gaps = 19/277 (6%)

Query: 121  GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180
            G+ G+G S  S  +       T S    G   S  G  S+ +  +  GTI      T   
Sbjct: 1722 GRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGE-SESIVHERHGTIHGQTGDTT-- 1778

Query: 181  MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240
                      + A + H  S Q GS+    +SS       S+G S   QRP +      Q
Sbjct: 1779 ----------RHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQ 1828

Query: 241  GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300
              SQ   G+ E   ++   +          +   GHG      SS T +      E S  
Sbjct: 1829 AGSQH--GESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDS 1886

Query: 301  HYYEGG---NSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357
              + GG   +S ++  QA  Q G ++   + + Q    Q+    + G+ S  G   Q   
Sbjct: 1887 EVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPS-HGQTIQTGS 1945

Query: 358  YQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNY 394
               G+     S  +    PS       G+  GQ G++
Sbjct: 1946 RTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSH 1982



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 78/324 (24%), Positives = 112/324 (34%), Gaps = 27/324 (8%)

Query: 92  QSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPG 151
           + G   G  S G  S        P S    Q G G       Q       T S   S  G
Sbjct: 322 KGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCG 381

Query: 152 -YSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA--------- 201
            Y   G  S        G+ G + + ++    SN  S   Q  + S  S++         
Sbjct: 382 QYGSGGSQSCSNGQHEYGSCGRFSNSSS----SNEFSKCDQYGSGSSQSTSFEQHGTGLS 437

Query: 202 --QGGSQHYQGQSSIAMMGQGSQGSSM-MGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYS 258
              G  QH  G        + +   S+   Q   +  + S  G      GQ   +G+  S
Sbjct: 438 QSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGS 497

Query: 259 HSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQS--YDRSFEESTQHYYEGGNSQYSQQQAG 316
            S G +   GQ     G      Q  S + QS  + +    S Q  Y G +   S Q +G
Sbjct: 498 GS-GQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSY-GQHGSGSSQSSG 555

Query: 317 Y-QQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTA 375
           Y Q G+ +   + Q    S QS    Q G GS Q +     G   GQ   +G + + ++ 
Sbjct: 556 YGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHES-RSG 614

Query: 376 PSAQQQRPYGYEQ----GQYGNYQ 395
            S+  Q   G  Q    GQ+G+ Q
Sbjct: 615 QSSYGQHSSGSSQSSGYGQHGSRQ 638



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 75/321 (23%), Positives = 109/321 (33%), Gaps = 67/321 (20%)

Query: 90   LTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISG 149
            ++ SG S G    GS S   STGL      Q + G+   H   + T   T+ TT  S SG
Sbjct: 1196 ISDSGQSTGFGQYGSGSGQ-STGLGQGESQQVESGS-TVHGRQETTHGQTINTTRHSQSG 1253

Query: 150  PGYSHAGPASQGVPMQGQGT-IGNYVSRTNINMQS-NPVSMMQQQAATSH--YSSAQGGS 205
                           QGQ T  G+ V+R   + QS N  S +  + +  H  +   Q GS
Sbjct: 1254 ---------------QGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGS 1298

Query: 206  QHYQGQSSIAMMGQGS----------QGSSMMGQRPMAPYRPS---------------QQ 240
             HY    S     QG+           G S  GQ      R S                 
Sbjct: 1299 -HYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHS 1357

Query: 241  GSSQQYLGQEEYY---GEQYSHSQGAAEPMGQQYYPD----------GHGDYAYQQSSYT 287
            G S +   QE+ +   G Q+  S+       +  Y            GHG    + S  T
Sbjct: 1358 GVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTT 1417

Query: 288  EQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGS 347
             +      E S    + GG+ +   Q+  + Q  +Q        +    +  GQ      
Sbjct: 1418 GRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQ------ 1471

Query: 348  AQGAPSQYPGYQQGQGQQYGS 368
              G  +++  Y  G+  Q GS
Sbjct: 1472 -TGDTTRHAHYHHGKSTQRGS 1491



 Score = 30.8 bits (68), Expect = 2.2
 Identities = 42/189 (22%), Positives = 72/189 (38%), Gaps = 32/189 (16%)

Query: 187  SMMQQQAATSH--YSSAQGGSQHYQGQSSIAMMGQGSQGSSM-------------MGQRP 231
            S +  +A+ +H  ++ +Q GS+H Q  SS    G G QG++               GQ  
Sbjct: 2186 SEVHSEASPTHSGHTHSQAGSRHGQSGSS----GHGRQGTTHGQTGDTTRHAHYGYGQST 2241

Query: 232  MAPYRPS-QQGSSQQYLGQEEYYG----EQYSHSQGAAEPMGQQYYPDGHG--DYAYQQS 284
                R + ++GS        E +         H QG A    +Q     HG  +  + Q+
Sbjct: 2242 QRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQT 2301

Query: 285  SYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQG 344
              T +     + +STQ          S + + +Q  ++++Q +   Q     SY   +  
Sbjct: 2302 GDTTRHGHSGYGQSTQ------TGSRSSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYD 2355

Query: 345  YGSAQGAPS 353
            YG     PS
Sbjct: 2356 YGHTGYGPS 2364


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 67/233 (28%), Positives = 89/233 (38%), Gaps = 15/233 (6%)

Query: 148  SGPGYSHAGPASQGVPMQGQ--GTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGS 205
            SG GYS  G AS     QG+   T G   S    +  S   S   Q  + SH++S +G  
Sbjct: 824  SGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRH 883

Query: 206  QHYQGQS-SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAA 264
                GQS      G GS  S   G+      R S  G      GQ   +G + S  Q + 
Sbjct: 884  GSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSG 943

Query: 265  EPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQ 324
                       HG  +   SSY EQ   RS + S    + G +S  S     +  G+ Q 
Sbjct: 944  YTQ--------HGSGSGHSSSY-EQHGSRSGQSSRSEQH-GSSSGSSSSYGQHGSGSRQS 993

Query: 325  QTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPS 377
              + Q    S QS    +  +GS  G  S Y  Y+ G G  + S R P  + S
Sbjct: 994  LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSG--WSSSRGPYESGS 1044



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 87/332 (26%), Positives = 118/332 (35%), Gaps = 34/332 (10%)

Query: 91   TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGP 150
            + SG S      GS S   S+G        GQ   G  H S  +++       S S    
Sbjct: 1642 SSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSS 1700

Query: 151  GYSHAGPASQGVPMQGQ---------------GTIGNYVSRTNINMQSNPVSMMQQQAAT 195
            G+   G  S   P +G+                  G   SR     +S   S+  Q  + 
Sbjct: 1701 GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 1760

Query: 196  SHYSSAQGGSQHYQGQSSIAMMGQ---GSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEY 252
            S +SSA   SQH  G       GQ    S  SS   Q   +  + S  G       Q   
Sbjct: 1761 SGHSSAY--SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSS 1818

Query: 253  YGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYT--EQSYDRSFEESTQHYYEGGNSQY 310
            YG+Q S S G +   G+     GH     Q  S +    S  R    S Q    G +   
Sbjct: 1819 YGQQGSGS-GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 1877

Query: 311  SQQQAGYQQ---GAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQ--- 364
            S Q +GY Q   G+    +Y Q    S QS  G+Q  +GS+ G+ S Y  +  G  Q   
Sbjct: 1878 SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQ--HGSSSGSSSSYGQHGSGSRQSLG 1935

Query: 365  --QYGSYRAPQTAPSAQQQRPYGYEQGQYGNY 394
              Q+GS      +PS  +      +   YG Y
Sbjct: 1936 HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY 1967



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 88/327 (26%), Positives = 118/327 (36%), Gaps = 45/327 (13%)

Query: 88   GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVS-MQQTAPNTLPTTSMS 146
            G+ ++   S G H  GS       G   SS   GQ G+G    S       ++  ++S S
Sbjct: 2542 GSGSRQSPSYGRHGSGS-------GRSSSS---GQHGSGLGESSGFGHHESSSGQSSSYS 2591

Query: 147  ISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQ 206
              G G  H+    Q     GQ + G           S   S   Q  + S  SS  G   
Sbjct: 2592 QHGSGSGHSSGYGQHGSRSGQSSRGE-----RHGSSSGSSSHYGQHGSGSRQSSGHGRQG 2646

Query: 207  HYQGQS-SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265
               GQS S    G G   SS  GQ      R S +G  +  LG    +G+   H  G+  
Sbjct: 2647 SGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQ---HESGSGH 2703

Query: 266  PMGQQYYPDGHGDYAYQ--------QSSYTEQSYDRSFEESTQHYYEGGNSQ---YSQQQ 314
                  +  G G +  Q        QSS  +Q    + + S+  +   G+SQ   Y +  
Sbjct: 2704 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHG 2763

Query: 315  AGYQQ---------GAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ 365
            AG  Q         G+ Q  +Y Q    S QS    Q G GS Q   S   G     G  
Sbjct: 2764 AGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGS 2823

Query: 366  YGSY---RAPQTAP--SAQQQRPYGYE 387
             GSY       T+P    Q+QR Y Y+
Sbjct: 2824 SGSYFLSFPSSTSPYEYVQEQRCYFYQ 2850



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 73/306 (23%), Positives = 108/306 (35%), Gaps = 21/306 (6%)

Query: 88  GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSI 147
           G+ +   SSQG H   S   A S+G   SS  Q    +   H S  + +      +S S 
Sbjct: 365 GSGSGHSSSQGQHGSTS-GQASSSGQHGSSSRQSS--SYGQHESASRHSSGRGQHSSGSG 421

Query: 148 SGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQH 207
             PG+   G  S   P  GQ         T     S+    +     +S +   +  S+H
Sbjct: 422 QSPGHGQRGSGSGQSPSSGQ-------HGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEH 474

Query: 208 YQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPM 267
             G +        S G    G R     R  +QGSS    G    YG+   H  G+ + +
Sbjct: 475 SSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSA---GSSSSYGQ---HGSGSRQSL 528

Query: 268 GQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTY 327
           G   +  G G    Q  S +   ++    +S+ +   G  S  S  +  Y+ G+      
Sbjct: 529 GHSRHGSGSG----QSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGL 584

Query: 328 SQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYE 387
             Q+  S QS    Q G  S   +     G   GQ    G + A     S+  Q   G  
Sbjct: 585 GHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSS 644

Query: 388 Q-GQYG 392
           Q  +YG
Sbjct: 645 QSSRYG 650



 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 75/316 (23%), Positives = 114/316 (36%), Gaps = 25/316 (7%)

Query: 88   GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVS-MQQTAPNTLPTTSMS 146
            G+ ++   S G H  GS       G   SS   GQ G+G    S       ++  ++S S
Sbjct: 1602 GSGSRQSPSYGRHGSGS-------GRSSSS---GQHGSGLGESSGFGHHESSSGQSSSYS 1651

Query: 147  ISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQ 206
              G G  H+    Q     GQ + G           S   S   Q  + S  SS  G   
Sbjct: 1652 QHGSGSGHSSGYGQHGSRSGQSSRGE-----RHGSSSRSSSRYGQHGSGSRQSSGHGRQG 1706

Query: 207  HYQGQS-SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265
               GQS S    G G   SS  GQ      R S +G  +   G    +G+   H  G+  
Sbjct: 1707 SGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ---HESGSGH 1763

Query: 266  PMGQQYYPDGHGDYAYQ----QSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY-QQG 320
                  +  G G +  Q     +S    ++D+    + Q    G +   S Q + Y QQG
Sbjct: 1764 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG 1823

Query: 321  AAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380
            +   Q+ S+ ++ S   +      +GS  G  S    +  G GQ  G      ++  +  
Sbjct: 1824 SGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1883

Query: 381  QRPYGYEQGQYGNYQQ 396
               +G   G   +Y+Q
Sbjct: 1884 YTQHGSGSGHSSSYEQ 1899



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 86/348 (24%), Positives = 124/348 (35%), Gaps = 37/348 (10%)

Query: 76   PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQT 135
            P       + G G  + SG S G    GS S   S+G        GQ      H S    
Sbjct: 690  PHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSH-SSGYRKHGSRSGQSSRSEQHGSSSGL 748

Query: 136  APNTLPTTSMSISGPGYSHAGPASQGVPMQGQ--------GTIGNYVSRTNINMQSNPVS 187
            + +     S S    G+   G  S   P + +         + G + S T+ +       
Sbjct: 749  SSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYE 808

Query: 188  MMQQQAAT--SHYS-SAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244
                QA+    H S S QG SQH  G +S     QG  GS+  GQ   +    S  G S 
Sbjct: 809  SGSGQASGFGQHESGSGQGYSQH--GSASGHFSSQGRHGSTS-GQSSSSGQHDSSSGQSS 865

Query: 245  QYLGQEEYYGEQYS----HSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300
             Y GQ E      S    H  G+ +  G      G G    Q  SY           S+ 
Sbjct: 866  SY-GQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG----QSPSYGRHGSGSGRSSSSG 920

Query: 301  HYYEG-------GNSQYSQQQAGY-QQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAP 352
             +  G       G+   S Q +GY Q G+    + S +Q+ S+     + + +GS+ G+ 
Sbjct: 921  RHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSS 980

Query: 353  SQYPGYQQGQGQ-----QYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQ 395
            S Y  +  G  Q     Q+GS      +PS  +      +   YG Y+
Sbjct: 981  SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYR 1028



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 91/353 (25%), Positives = 132/353 (37%), Gaps = 58/353 (16%)

Query: 88   GALTQSGSSQGLHSQGSLSDA------ISTGLPPS----------SLLQGQIGNGPSHVS 131
            G+ ++S S  G H  GS   +        +G  PS          S   GQ G+G    S
Sbjct: 1680 GSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS 1739

Query: 132  MQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQ 191
             +   P    +   S+ G   S +G +S      G G+ G++ S+      S   S   Q
Sbjct: 1740 SR--GPYESRSGHSSVFGQHESGSGHSS-AYSQHGSGS-GHFCSQGQHGSTSGQSSTFDQ 1795

Query: 192  QAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEE 251
            + +++  SS+ G  QH  G S  +  GQ   GS   GQ P      S  G S  Y GQ  
Sbjct: 1796 EGSSTGQSSSHG--QHGSGSSQSSSYGQQGSGS---GQSPSRGRHGSGSGHSSSY-GQHG 1849

Query: 252  YYGEQYSHSQGA-AEPMGQQYYPDGHGDYAYQQSSYT------------EQSYDRSFEES 298
              G  +S S G      GQ      H   ++Q S YT            EQ   RS + S
Sbjct: 1850 S-GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 1908

Query: 299  TQHYY---EGGNSQYSQQQAGYQQ---------GAAQQQTYSQQQYPSQQSYPGQQQGYG 346
                +    G +S Y Q  +G +Q         G+ Q  + S+ ++ S          YG
Sbjct: 1909 RGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYG 1968

Query: 347  SAQGAPSQYPGYQQGQGQQYG----SYRAPQTAPSAQQQRPYGYE--QGQYGN 393
            S  G  S    Y+ G G   G      R+ Q++   Q     G+    GQ+G+
Sbjct: 1969 SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2021



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 75/316 (23%), Positives = 113/316 (35%), Gaps = 25/316 (7%)

Query: 88   GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVS-MQQTAPNTLPTTSMS 146
            G+ ++   S G H  GS       G   SS   GQ G G    S       ++  ++S S
Sbjct: 2072 GSGSRQSPSYGRHGSGS-------GRSSSS---GQHGPGLGESSGFGHHESSSGQSSSYS 2121

Query: 147  ISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQ 206
              G G  H+    Q     GQ + G           S   S   Q  + S  SS  G   
Sbjct: 2122 QHGSGSGHSSGYGQHGSRSGQSSRGE-----RHGSSSGSSSRYGQHGSGSRQSSGHGRQG 2176

Query: 207  HYQGQS-SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265
               G S S    G GS  SS  GQ      R S +G  +   G    +G+   H  G+  
Sbjct: 2177 SGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ---HESGSGH 2233

Query: 266  PMGQQYYPDGHGDYAYQ----QSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY-QQG 320
                  +  G G +  Q     +S    ++D+    + Q    G +   S Q + Y QQG
Sbjct: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG 2293

Query: 321  AAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380
            +   Q+ S+ ++ S   +      +GS  G  S    +  G GQ  G      ++  +  
Sbjct: 2294 SGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 2353

Query: 381  QRPYGYEQGQYGNYQQ 396
               +G   G   +Y+Q
Sbjct: 2354 YTQHGSGSGHSSSYEQ 2369



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 88/343 (25%), Positives = 123/343 (35%), Gaps = 40/343 (11%)

Query: 86   GPGALTQSG-----SSQGL---HSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAP 137
            GPG    SG     SS G    +SQ       S+G        GQ   G  H S   ++ 
Sbjct: 2098 GPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS 2157

Query: 138  NTLPTTSMSISGPGYSHAGPASQGVPMQGQ---------------GTIGNYVSRTNINMQ 182
                  S S    G+   G  S   P +G+                  G   SR     +
Sbjct: 2158 RYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESR 2217

Query: 183  SNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQ---GSQGSSMMGQRPMAPYRPSQ 239
            S   S+  Q  + S +SSA   SQH  G       GQ    S  SS   Q   +  + S 
Sbjct: 2218 SGHSSVFGQHESGSGHSSAY--SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275

Query: 240  QGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYT--EQSYDRSFEE 297
             G       Q   YG+Q S S G +   G+     GH     Q  S +    S  R    
Sbjct: 2276 HGQHGSGSSQSSSYGQQGSGS-GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 2334

Query: 298  STQHYYEGGNSQYSQQQAGY-QQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYP 356
            S Q    G +   S Q +GY Q G+    + S +Q+ S+     + + +GS+ G+ S Y 
Sbjct: 2335 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYG 2394

Query: 357  GYQQGQGQ-----QYGSYRAPQTAPSAQQQRPYGYEQGQYGNY 394
             +  G  Q     Q+GS      +PS  +   +G   GQ  +Y
Sbjct: 2395 QHGSGSRQSLGHGQHGSGSGQSPSPSRGR---HGSGSGQSSSY 2434



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 90/354 (25%), Positives = 131/354 (37%), Gaps = 60/354 (16%)

Query: 88   GALTQSGSSQGLHSQGSLSDA------ISTGLPPSSLLQGQIGNGPSHVSMQ-------- 133
            G+ + S S  G H  GS   +        +G  PS   +G+ G+G  H S          
Sbjct: 2150 GSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPS---RGRHGSGSGHSSSHGQHGSGSG 2206

Query: 134  ---QTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQ 190
                  P    +   S+ G   S +G +S      G G+ G++ S+      S   S   
Sbjct: 2207 RSSSRGPYESRSGHSSVFGQHESGSGHSS-AYSQHGSGS-GHFCSQGQHGSTSGQSSTFD 2264

Query: 191  QQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQE 250
            Q+ +++  SS+ G  QH  G S  +  GQ   GS   GQ P      S  G S  Y GQ 
Sbjct: 2265 QEGSSTGQSSSHG--QHGSGSSQSSSYGQQGSGS---GQSPSRGRHGSGSGHSSSY-GQH 2318

Query: 251  EYYGEQYSHSQGA-AEPMGQQYYPDGHGDYAYQQSSYT------------EQSYDRSFEE 297
               G  +S S G      GQ      H   ++Q S YT            EQ   RS + 
Sbjct: 2319 GS-GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQS 2377

Query: 298  STQHYY---EGGNSQYSQQQAGYQQ---------GAAQQQTYSQQQYPSQQSYPGQQQGY 345
            S    +    G +S Y Q  +G +Q         G+ Q  + S+ ++ S          Y
Sbjct: 2378 SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPY 2437

Query: 346  GSAQGAPSQYPGYQQGQGQQYG----SYRAPQTAPSAQQQRPYGYE--QGQYGN 393
            GS  G  S    Y+ G G   G      R+ Q++   Q     G+    GQ+G+
Sbjct: 2438 GSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2491



 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 83/312 (26%), Positives = 114/312 (36%), Gaps = 25/312 (8%)

Query: 91  TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQ-TAPNTLPTTSMSISG 149
           ++  S +G HS GS       G  P    +G  G+G S  S Q  T      ++   +SG
Sbjct: 407 SRHSSGRGQHSSGS-------GQSPGHGQRGS-GSGQSPSSGQHGTGFGRSSSSGPYVSG 458

Query: 150 PGYSH-------AGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQ 202
            GYS        +   S G    G G+ G+         +S   S  ++Q +++  SS+ 
Sbjct: 459 SGYSSGFGHHESSSEHSSGYTQHGSGS-GHSSGHGQHGSRSGQSSRGERQGSSAGSSSSY 517

Query: 203 GGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQG 262
           G  QH  G  S   +G    GS   GQ P       + GS Q        YG   S S+G
Sbjct: 518 G--QH--GSGSRQSLGHSRHGSGS-GQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG 572

Query: 263 AAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA 322
             E         GH +    QSS   Q    S   ST H   G  S  S     +   + 
Sbjct: 573 PYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSST-HGQHGSTSGQSSSCGQHGATSG 631

Query: 323 QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQR 382
           Q  ++ Q    S QS    QQG GS Q       G   G    YG + +     S+    
Sbjct: 632 QSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSS--NG 689

Query: 383 PYGYEQGQYGNY 394
           P+G   GQ   +
Sbjct: 690 PHGSVSGQSSGF 701



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 85/332 (25%), Positives = 115/332 (34%), Gaps = 33/332 (9%)

Query: 92   QSGSSQG---LHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSIS 148
            Q GSS G    H Q   +   S+         GQ  +   H S    +       S S  
Sbjct: 2475 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 2534

Query: 149  GPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208
             PG+   G  S+  P  G+   G+   R++ + Q    S + + +   H+ S+ G S  Y
Sbjct: 2535 SPGHGQRGSGSRQSPSYGRHGSGS--GRSSSSGQHG--SGLGESSGFGHHESSSGQSSSY 2590

Query: 209  --QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQY------LGQEEYYGEQYSHS 260
               G  S    G G  G S  GQ        S  GSS  Y        Q   +G Q S S
Sbjct: 2591 SQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 2649

Query: 261  QGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEEST--------QHYYEGGNSQ-YS 311
             G +   G+     GH     Q  S + +S  R   ES         QH    G+S  YS
Sbjct: 2650 -GQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYS 2708

Query: 312  QQQAG----YQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ---GQGQ 364
            Q  +G      QG     +     +  + S  GQ   YG      SQ  GY +   G GQ
Sbjct: 2709 QHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQ 2768

Query: 365  QYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
                 R    +  +     +G   GQ   Y Q
Sbjct: 2769 SLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQ 2800



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 81/304 (26%), Positives = 114/304 (37%), Gaps = 20/304 (6%)

Query: 93   SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGY 152
            SG S G   +GS      +G  PS    G+ G+G    S + ++     + S   SG G+
Sbjct: 887  SGQSPGHGQRGS-----GSGQSPS---YGRHGSG----SGRSSSSGRHGSGSGQSSGFGH 934

Query: 153  SHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQS 212
              +   S G    G G+ G+  S      +S   S  +Q  ++S  SS+ G  QH  G  
Sbjct: 935  KSSSGQSSGYTQHGSGS-GHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYG--QH--GSG 989

Query: 213  SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYY 272
            S   +G G  GS   GQ P         GS Q         G  +S S+G  E       
Sbjct: 990  SRQSLGHGQHGSGS-GQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSS 1048

Query: 273  PDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQY 332
              GH +    QSS   Q    S   ST H   G  S  S     +   + Q  ++ Q   
Sbjct: 1049 GLGHRESRSGQSSGYGQHGSSSGHSST-HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGS 1107

Query: 333  PSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGY-EQGQY 391
             S QS    +QG GS Q       G    Q   YG + +     S+  Q   G  E   +
Sbjct: 1108 GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGF 1167

Query: 392  GNYQ 395
            G+++
Sbjct: 1168 GHHE 1171



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 79/317 (24%), Positives = 116/317 (36%), Gaps = 29/317 (9%)

Query: 92   QSGSSQG---LHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSIS 148
            Q GSS G    H Q   +   S+         GQ  +   H S    +       S S  
Sbjct: 2005 QHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 2064

Query: 149  GPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208
             PG+   G  S+  P  G+   G+   R++ + Q  P   + + +   H+ S+ G S  Y
Sbjct: 2065 SPGHGQRGSGSRQSPSYGRHGSGS--GRSSSSGQHGP--GLGESSGFGHHESSSGQSSSY 2120

Query: 209  --QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQY------LGQEEYYGEQYSHS 260
               G  S    G G  G S  GQ        S  GSS +Y        Q   +G Q S S
Sbjct: 2121 SQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGS 2179

Query: 261  QGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQG 320
             G +   G+     GH     Q  S + +S  R   ES      G +S + Q    ++ G
Sbjct: 2180 -GHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESR----SGHSSVFGQ----HESG 2230

Query: 321  AAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380
            +     YSQ    S       Q G  S Q +     G   GQ   +G + +  +  S+  
Sbjct: 2231 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYG 2290

Query: 381  QRPYGYEQ----GQYGN 393
            Q+  G  Q    G++G+
Sbjct: 2291 QQGSGSGQSPSRGRHGS 2307



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 90/339 (26%), Positives = 126/339 (37%), Gaps = 43/339 (12%)

Query: 88   GALTQSGSSQGLHSQGSLSDAISTGLPPS----SLLQGQIGNGPSHVSMQ---------Q 134
            G+ T   SS G H  GS S + S G   S    S  +G+ G+G  H S            
Sbjct: 1797 GSSTGQSSSHGQHGSGS-SQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS 1855

Query: 135  TAPNTLPTTSMSISGPGYSHAGP-ASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQA 193
            ++     + S   SG G+  +    S G    G G+ G+  S      +S   S  +Q  
Sbjct: 1856 SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS-GHSSSYEQHGSRSGQSSRGEQHG 1914

Query: 194  ATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYY 253
            ++S  SS+ G  QH  G  S   +G G  GS   GQ P +P R  + GS     GQ   Y
Sbjct: 1915 SSSGSSSSYG--QH--GSGSRQSLGHGQHGSGS-GQSP-SPSR-GRHGSGS---GQSSSY 1964

Query: 254  GEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQS-----YDRSFEESTQHYYEGGNS 308
            G  Y    G +   G      GH      + S + QS     +  S   S+ H   G  S
Sbjct: 1965 GP-YGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSAS 2023

Query: 309  QYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYG- 367
              S     +   + Q  ++ Q    S QS    +QG GS Q       G    Q   YG 
Sbjct: 2024 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 2083

Query: 368  -------SYRAPQTAPSAQQQRPYGYEQ---GQYGNYQQ 396
                   S  + Q  P   +   +G+ +   GQ  +Y Q
Sbjct: 2084 HGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 74/296 (25%), Positives = 106/296 (35%), Gaps = 29/296 (9%)

Query: 119 LQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTN 178
           ++G +  G   +S + +          S SG   S+    S      G+G  G+   ++ 
Sbjct: 144 VRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSP 203

Query: 179 INMQSNPVSMMQQQAATSHYSSAQ--GGSQHYQ--GQSS-IAMMGQGSQGSSMMGQRPMA 233
              Q    S       T    S Q  G SQH    GQSS  +  G GS  SS  GQ    
Sbjct: 204 NYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSR 263

Query: 234 PYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDG---------HGDYAYQQS 284
             + S+    +   G    YG+   H  G+ + +G      G         HG  +   S
Sbjct: 264 SGQSSRGERHRSSSGSSSSYGQ---HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSS 320

Query: 285 SYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQ---GAAQQQTYSQQQYPSQQSYPGQ 341
           S+ +     S+  S  HY  G     S Q +G+ Q   G+ Q   YS+    S  S    
Sbjct: 321 SHGQHGSGSSYSYSRGHYESG-----SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQG 375

Query: 342 QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQ----GQYGN 393
           Q G  S Q + S   G    Q   YG + +     S + Q   G  Q    GQ G+
Sbjct: 376 QHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGS 431



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 79/311 (25%), Positives = 118/311 (37%), Gaps = 26/311 (8%)

Query: 88   GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSI 147
            G+ + S SS G H  GS            SL  GQ G+G           +   +   S 
Sbjct: 974  GSSSGSSSSYGQHGSGSRQ----------SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 1023

Query: 148  SGPGYSHAGPASQGVPMQ-GQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQ 206
             GP  S +G +S   P + G G       R + + QS+      Q  ++S +SS  G   
Sbjct: 1024 YGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG---QHGSSSGHSSTHGQHG 1080

Query: 207  HYQGQSS-IAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265
               GQSS     G  S  SS  GQ      + S  G      GQ   +G++ S S+ +  
Sbjct: 1081 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 1140

Query: 266  PMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQ 325
              G+     G    + Q  S   +S      ES+     G +S YSQ    +  G+    
Sbjct: 1141 -YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS----GQSSSYSQ----HGSGSGHSS 1191

Query: 326  TYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYG 385
             Y Q    S QS  G++  +GS+ G+ S Y  +  G  Q  G  R    +  +  +  +G
Sbjct: 1192 GYGQHGSRSGQSSRGER--HGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG 1249

Query: 386  YEQGQYGNYQQ 396
               G   ++ Q
Sbjct: 1250 SGLGHSSSHGQ 1260



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 70/299 (23%), Positives = 101/299 (33%), Gaps = 29/299 (9%)

Query: 92   QSGSSQG---LHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSIS 148
            Q GSS G    H Q   +   S+         GQ  +   H S    +       S S  
Sbjct: 1065 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 1124

Query: 149  GPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208
             PG+   G  S+  P  G+   G+   R++ + Q    S + + +   H+ S+ G S  Y
Sbjct: 1125 SPGHGQRGSGSRQSPSYGRHGSGS--GRSSSSGQHG--SGLGESSGFGHHESSSGQSSSY 1180

Query: 209  QGQSSIAMMGQG-SQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPM 267
                S    G G S G    G R     R  + GSS    G   +YG+   H  G+ +  
Sbjct: 1181 SQHGS----GSGHSSGYGQHGSRSGQSSRGERHGSSS---GSSSHYGQ---HGSGSRQSS 1230

Query: 268  GQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTY 327
            G      G G       S +   +      S+ H   G  S  S  +  Y+  +     +
Sbjct: 1231 GHGRQGSGSG------HSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF 1284

Query: 328  SQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGY 386
             Q +  S  S    Q G GS         G   GQ   +      Q   S  Q   YG+
Sbjct: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF-----DQEGSSTGQSSSYGH 1338



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 85/323 (26%), Positives = 119/323 (36%), Gaps = 23/323 (7%)

Query: 88   GALTQSGSSQGLHSQGSLSDAISTGLPPS----SLLQGQIGNGPSHVSMQ---------Q 134
            G+ T   SS G H  GS S + S G   S    S  +G+ G+G  H S            
Sbjct: 2267 GSSTGQSSSHGQHGSGS-SQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS 2325

Query: 135  TAPNTLPTTSMSISGPGYSHAGP-ASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQA 193
            ++     + S   SG G+  +    S G    G G+ G+  S      +S   S  ++  
Sbjct: 2326 SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS-GHSSSYEQHGSRSGQSSRGERHG 2384

Query: 194  ATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYY 253
            ++S  SS+ G  QH  G  S   +G G  GS   GQ P         GS Q         
Sbjct: 2385 SSSGSSSSYG--QH--GSGSRQSLGHGQHGSGS-GQSPSPSRGRHGSGSGQSSSYSPYGS 2439

Query: 254  GEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQ 313
            G  +S S+G  E         GH +    QSS   Q    S   ST H   G  S  S  
Sbjct: 2440 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST-HGQHGSTSGQSSS 2498

Query: 314  QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQ 373
               +   + Q  ++ Q    S QS    +QG GS Q       G    Q   YG + +  
Sbjct: 2499 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 2558

Query: 374  TAPSAQQQRPYGY-EQGQYGNYQ 395
               S+  Q   G  E   +G+++
Sbjct: 2559 GRSSSSGQHGSGLGESSGFGHHE 2581



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 79/312 (25%), Positives = 111/312 (35%), Gaps = 11/312 (3%)

Query: 93  SGSSQGLHSQGSLSDAISTG-----LPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSI 147
           SG S G    GS S   S G        SS   GQ G+G S  S+  +   +    S S 
Sbjct: 485 SGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSG-SRQSLGHSRHGSGSGQSPSP 543

Query: 148 SGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQH 207
           S   +      S      G G+ G   SR      S   S +  Q + S  SS  G    
Sbjct: 544 SRGRHESGSRQSSSYGPHGYGS-GRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGS 602

Query: 208 YQGQSSI-AMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEP 266
             G SS     G  S  SS  GQ      + S  G       Q   YG+Q S S G +  
Sbjct: 603 SSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGS-GQSPS 661

Query: 267 MGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEG-GNSQYSQQQAGYQQ-GAAQQ 324
            G+     GH     Q  S +  S       S      G G+   S Q +GY Q G+   
Sbjct: 662 RGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSS 721

Query: 325 QTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPY 384
            +   +++ S+     + + +GS+ G  S Y  +  G  Q  G  R    +  +  +  +
Sbjct: 722 HSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRH 781

Query: 385 GYEQGQYGNYQQ 396
           G   G   ++ Q
Sbjct: 782 GSSSGHSSSHGQ 793



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 80/330 (24%), Positives = 123/330 (37%), Gaps = 33/330 (10%)

Query: 91   TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGP 150
            + SG S      GS S   S+G        GQ   G  H S   ++ +     S S    
Sbjct: 1172 SSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 1230

Query: 151  GYSHAGPASQGVPMQGQ--GTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208
            G+   G  S   P +G+    +G+  S       S   S      + S +SS  G  +  
Sbjct: 1231 GHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 1290

Query: 209  QGQSS-IAMMGQGSQGSSMMGQRPMAPYRPS---QQGSSQQYLGQEEYYGEQYSHSQGAA 264
             G SS  +  G GS      GQ      + S   Q+GSS    GQ   YG + S S  ++
Sbjct: 1291 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSS---TGQSSSYGHRGSGSSQSS 1347

Query: 265  ------EPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEG-------GNSQYS 311
                     GQ      HG  +   SSY +      +  S+  +  G       G+ + S
Sbjct: 1348 GYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 1407

Query: 312  QQQAG--YQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQ----- 364
              Q+    Q G+    + S +Q+ S+     + + +GS+ G+ S Y  +  G  Q     
Sbjct: 1408 SWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 1467

Query: 365  QYGSYRAPQTAPSAQQQRPYGYEQGQYGNY 394
            Q+GS      +PS  +   +G   GQ  +Y
Sbjct: 1468 QHGSGSGQSPSPSRGR---HGSGSGQSSSY 1494



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 74/306 (24%), Positives = 106/306 (34%), Gaps = 22/306 (7%)

Query: 88   GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSI 147
            G+ +   SSQG H   S   + S+G   SS   GQ  +   H S    A       S S 
Sbjct: 832  GSASGHFSSQGRHGSTS-GQSSSSGQHDSS--SGQSSSYGQHESASHHASGRGRHGSGSG 888

Query: 148  SGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQH 207
              PG+   G  S   P  G+   G+  S ++    S       Q +   H SS+   S +
Sbjct: 889  QSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGS----GQSSGFGHKSSSGQSSGY 944

Query: 208  YQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPM 267
             Q  S         Q  S  GQ   +    S  GSS  Y GQ         H  G+ + +
Sbjct: 945  TQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSY-GQ---------HGSGSRQSL 994

Query: 268  GQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTY 327
            G   +  G G    Q  S +   +     +S+ +      S +S  +  Y+ G+      
Sbjct: 995  GHGQHGSGSG----QSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGL 1050

Query: 328  SQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYE 387
              ++  S QS    Q G  S   +     G   GQ    G + A     S+  Q   G  
Sbjct: 1051 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1110

Query: 388  QGQ-YG 392
            Q   YG
Sbjct: 1111 QSSGYG 1116



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 76/311 (24%), Positives = 111/311 (35%), Gaps = 17/311 (5%)

Query: 92   QSGSSQG---LHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSIS 148
            Q GSS G    H Q   +   S+         GQ  +   H S    +       S S  
Sbjct: 1535 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 1594

Query: 149  GPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208
             PG+   G  S+  P  G+   G+   R++ + Q    S + + +   H+ S+ G S  Y
Sbjct: 1595 SPGHGQRGSGSRQSPSYGRHGSGS--GRSSSSGQHG--SGLGESSGFGHHESSSGQSSSY 1650

Query: 209  --QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEP 266
               G  S    G G  G S  GQ        S   SS +Y GQ      Q S        
Sbjct: 1651 SQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSSRSSSRY-GQHGSGSRQSSGHGRQGSG 1708

Query: 267  MGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQT 326
             GQ      HG      SS+ +     S   S++  YE   S +S     ++ G+     
Sbjct: 1709 SGQSPSRGRHGSGLGHSSSHGQHG-SGSGRSSSRGPYE-SRSGHSSVFGQHESGSGHSSA 1766

Query: 327  YSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGY 386
            YSQ    S       Q G  S Q +     G   GQ   +G + +  +  S+  Q+  G 
Sbjct: 1767 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS 1826

Query: 387  EQ----GQYGN 393
             Q    G++G+
Sbjct: 1827 GQSPSRGRHGS 1837



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 71/305 (23%), Positives = 104/305 (34%), Gaps = 34/305 (11%)

Query: 92  QSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQ-QTAPNTLPTTSMSISGP 150
           Q GS+ G  S      A S      S   GQ G+G S  S   Q    +  + S    G 
Sbjct: 612 QHGSTSGQSSSCGQHGATSG----QSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGS 667

Query: 151 GYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG 210
            + H+  +S G    G G   +     +++ QS+          +S YS    GS H   
Sbjct: 668 DFGHS--SSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSH--- 722

Query: 211 QSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQ 270
                     S G    G R     R  Q GSS    G    YG+   H  G+ +  G  
Sbjct: 723 ----------SSGYRKHGSRSGQSSRSEQHGSSS---GLSSSYGQ---HGSGSHQSSGHG 766

Query: 271 YYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQ 330
               G G       S +   +  S   S+ H   G  +  S     Y+ G+ Q   + Q 
Sbjct: 767 RQGSGSG------HSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQH 820

Query: 331 QYPSQQSYP--GQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQ 388
           +  S Q Y   G   G+ S+QG      G     GQ   S     +    +    +   +
Sbjct: 821 ESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGR 880

Query: 389 GQYGN 393
           G++G+
Sbjct: 881 GRHGS 885



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 82/314 (26%), Positives = 115/314 (36%), Gaps = 24/314 (7%)

Query: 93   SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQ---------QTAPNTLPTT 143
            SGSSQ   S G       +G  PS   +G+ G+G  H S            ++     + 
Sbjct: 1341 SGSSQ---SSGYGRHGAGSGQSPS---RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1394

Query: 144  SMSISGPGYSHAGP-ASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQ 202
            S   SG G+  +    S G    G G+ G+  S      +S   S  ++  ++S  SS+ 
Sbjct: 1395 SGQSSGFGHHESSSWQSSGCTQHGSGS-GHSSSYEQHGSRSGQSSRGERHGSSSGSSSSY 1453

Query: 203  GGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQG 262
            G  QH  G  S   +G G  GS   GQ P         GS Q         G  +S S+G
Sbjct: 1454 G--QH--GSGSRQSLGHGQHGSGS-GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG 1508

Query: 263  AAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA 322
              E         GH +    QSS   Q    S   ST H   G  S  S     +   + 
Sbjct: 1509 PYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST-HGQHGSTSGQSSSCGQHGASSG 1567

Query: 323  QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQR 382
            Q  ++ Q    S QS    +QG GS Q       G    Q   YG + +     S+  Q 
Sbjct: 1568 QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 1627

Query: 383  PYGY-EQGQYGNYQ 395
              G  E   +G+++
Sbjct: 1628 GSGLGESSGFGHHE 1641



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 74/292 (25%), Positives = 102/292 (34%), Gaps = 34/292 (11%)

Query: 120  QGQIGNGPSHVS-MQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTN 178
            QGQ G+     S   Q   +T  ++S    G G S +    Q    QG G+ G   SR  
Sbjct: 1780 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQ----QGSGS-GQSPSRGR 1834

Query: 179  INMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSS--------------IAMMGQGSQGS 224
                S   S   Q  + S +SS+ G      GQSS                  G GS  S
Sbjct: 1835 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 1894

Query: 225  SMM---GQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAY 281
            S     G R     R  Q GSS    G    YG+   H  G+ + +G   +  G G    
Sbjct: 1895 SSYEQHGSRSGQSSRGEQHGSSS---GSSSSYGQ---HGSGSRQSLGHGQHGSGSG---- 1944

Query: 282  QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQ 341
            Q  S +   +     +S+ +   G  S +S  +  Y+ G+        ++  S QS    
Sbjct: 1945 QSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG 2004

Query: 342  QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQ-YG 392
            Q G  S   +     G   GQ    G + A     S+  Q   G  Q   YG
Sbjct: 2005 QHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 2056



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 77/331 (23%), Positives = 111/331 (33%), Gaps = 36/331 (10%)

Query: 91  TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGP 150
           + SG S G    GS S   S+G        GQ   G  H S   ++ +     S S    
Sbjct: 236 SSSGQSSGYSQHGSGSGH-SSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSL 294

Query: 151 GYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG 210
           G+   G  S+  P   +   G+  S ++    S       +    S      G  QH  G
Sbjct: 295 GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESG 354

Query: 211 Q---SSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYS--------- 258
               S  +  G GS  SS  GQ      + S  G       Q   YG+  S         
Sbjct: 355 SGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414

Query: 259 -HSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGG--------NSQ 309
            HS G+ +  G      G G    Q  S  +         S+  Y  G         +  
Sbjct: 415 QHSSGSGQSPGHGQRGSGSG----QSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHES 470

Query: 310 YSQQQAGYQQ---GAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQ-- 364
            S+  +GY Q   G+     + Q    S QS  G++Q  GS+ G+ S Y  +  G  Q  
Sbjct: 471 SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQ--GSSAGSSSSYGQHGSGSRQSL 528

Query: 365 ---QYGSYRAPQTAPSAQQQRPYGYEQGQYG 392
              ++GS      +PS  +      +   YG
Sbjct: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYG 559



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 73/292 (25%), Positives = 102/292 (34%), Gaps = 34/292 (11%)

Query: 120  QGQIGNGPSHVS-MQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTN 178
            QGQ G+     S   Q   +T  ++S    G G S +    Q    QG G+ G   SR  
Sbjct: 2250 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQ----QGSGS-GQSPSRGR 2304

Query: 179  INMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSS--------------IAMMGQGSQGS 224
                S   S   Q  + S +SS+ G      GQSS                  G GS  S
Sbjct: 2305 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 2364

Query: 225  SMM---GQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAY 281
            S     G R     R  + GSS    G    YG+   H  G+ + +G   +  G G    
Sbjct: 2365 SSYEQHGSRSGQSSRGERHGSSS---GSSSSYGQ---HGSGSRQSLGHGQHGSGSG---- 2414

Query: 282  QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQ 341
            Q  S +   +     +S+ +   G  S +S  +  Y+ G+        ++  S QS    
Sbjct: 2415 QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG 2474

Query: 342  QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQ-YG 392
            Q G  S   +     G   GQ    G + A     S+  Q   G  Q   YG
Sbjct: 2475 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 2526



 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 73/292 (25%), Positives = 102/292 (34%), Gaps = 34/292 (11%)

Query: 120  QGQIGNGPSHVS-MQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTN 178
            QGQ G+     S   Q   +T  ++S    G G S     S G    G G+ G   SR  
Sbjct: 1310 QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQ----SSGYGRHGAGS-GQSPSRGR 1364

Query: 179  INMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSS--------------IAMMGQGSQGS 224
                S   S   Q  + S +SS+ G      GQSS                  G GS  S
Sbjct: 1365 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHS 1424

Query: 225  SMM---GQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAY 281
            S     G R     R  + GSS    G    YG+   H  G+ + +G   +  G G    
Sbjct: 1425 SSYEQHGSRSGQSSRGERHGSSS---GSSSSYGQ---HGSGSRQSLGHGQHGSGSG---- 1474

Query: 282  QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQ 341
            Q  S +   +     +S+ +   G  S +S  +  Y+ G++       ++  S QS    
Sbjct: 1475 QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYG 1534

Query: 342  QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQ-YG 392
            Q G  S   +     G   GQ    G + A     S+  Q   G  Q   YG
Sbjct: 1535 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 1586



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 75/307 (24%), Positives = 107/307 (34%), Gaps = 32/307 (10%)

Query: 95   SSQGLHSQGSLSDAISTGLPPSSLLQG----QIGNGPSHVSMQQTAPNTLPTTSMSISGP 150
            SS G H  GS   +   G   SS  Q     Q G+G  H S  +   +    +  S  G 
Sbjct: 1386 SSSGRHGSGS-GQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSR---SGQSSRGE 1441

Query: 151  GYSHAGPASQGVPMQGQGTIGNYVSRTNINM-QSNPVSMMQQQAATSHYSSAQGGSQHYQ 209
             +  +  +S      G G      SR ++   Q    S      +   + S  G S    
Sbjct: 1442 RHGSSSGSSSSYGQHGSG------SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS---- 1491

Query: 210  GQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQ 269
              SS +  G GS  SS  G         S  G  +   GQ   YG Q+  S G +   GQ
Sbjct: 1492 --SSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYG-QHGSSSGHSSTHGQ 1548

Query: 270  QYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQ 329
                  HG  + Q SS  +  +  S  +S+ H   G  S  S        G+ Q   + Q
Sbjct: 1549 ------HGSTSGQSSSCGQ--HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 1600

Query: 330  QQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQG 389
            +   S+QS    + G GS  G  S    +  G G+  G      ++  +     +G   G
Sbjct: 1601 RGSGSRQSPSYGRHGSGS--GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 1658

Query: 390  QYGNYQQ 396
                Y Q
Sbjct: 1659 HSSGYGQ 1665


>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
          Length = 592

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 62/192 (32%), Positives = 82/192 (42%), Gaps = 25/192 (13%)

Query: 196 SHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQR--PMAPYRPSQQGSSQQYLGQEEYY 253
           S+ +    GSQ Y GQ+S +  G G    S  GQ     + Y  SQ G SQ Y G E   
Sbjct: 16  SYSTYGNPGSQGY-GQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQ- 73

Query: 254 GEQYSHSQGAAEPMGQQYYPDGHG------------DYAYQQSSYTEQS-YDR---SFEE 297
            +Q S+SQ      GQQ   +  G            DY  QQ SY +QS YD+   S++E
Sbjct: 74  -KQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG-QQDSYDQQSGYDQHQGSYDE 131

Query: 298 STQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357
             Q  Y+  +  YSQ Q  Y         ++Q        Y    +GYG +QG      G
Sbjct: 132 --QSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGG 189

Query: 358 Y-QQGQGQQYGS 368
           Y + G+G   GS
Sbjct: 190 YDKDGRGPMTGS 201



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 46/147 (31%), Positives = 60/147 (40%), Gaps = 23/147 (15%)

Query: 258 SHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY 317
           S+ Q   E      Y +  G   Y Q+S +   Y ++ + S    Y G +S Y Q Q+GY
Sbjct: 6   SYGQSGGEQQSYSTYGNP-GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS-YGQSQSGY 63

Query: 318 QQGAA-----QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP 372
            Q        +Q +YSQQ Y +Q    GQQQ   S+     + P Y Q    Q  SY   
Sbjct: 64  SQSYGGYENQKQSSYSQQPYNNQ----GQQQNMESSGSQGGRAPSYDQPDYGQQDSY--- 116

Query: 373 QTAPSAQQQRPYGYEQGQY---GNYQQ 396
                  QQ  Y   QG Y    NY Q
Sbjct: 117 ------DQQSGYDQHQGSYDEQSNYDQ 137


>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
           sapiens]
          Length = 898

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 73/275 (26%), Positives = 98/275 (35%), Gaps = 32/275 (11%)

Query: 150 PGYSHAGPASQGVP----MQGQGTIGNYVSRTNINM--QSNPVSMMQQQAATSHY----- 198
           PG+   GP    VP    ++G+G  G+   R        +N    M   A    Y     
Sbjct: 625 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGN 684

Query: 199 SSAQGGSQHYQ--GQSSIAMMGQGS-------QGSSMMGQRPMAPYRPSQQGSSQQYLGQ 249
           S+  G SQ Y   G S  A  G G         GS   G    +P  P   G  Q + GQ
Sbjct: 685 SATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQ 744

Query: 250 EE-YYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNS 308
           ++  YG  Y   QG  +   Q  Y + +G    +Q  Y       S+  S      GG S
Sbjct: 745 QKPSYGSGYQSHQGQQQSYNQSPYSN-YGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGS 803

Query: 309 QYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGS 368
            Y+ +      G+  +   +          PG   GYG   G  S Y G Q G  Q   +
Sbjct: 804 DYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQ--SN 861

Query: 369 YRAPQTA------PSAQQ--QRPYGYEQGQYGNYQ 395
           Y +P +       PS+ Q  Q  YG       NYQ
Sbjct: 862 YNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQ 896


>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
           sapiens]
          Length = 894

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 73/275 (26%), Positives = 98/275 (35%), Gaps = 32/275 (11%)

Query: 150 PGYSHAGPASQGVP----MQGQGTIGNYVSRTNINM--QSNPVSMMQQQAATSHY----- 198
           PG+   GP    VP    ++G+G  G+   R        +N    M   A    Y     
Sbjct: 621 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGN 680

Query: 199 SSAQGGSQHYQ--GQSSIAMMGQGS-------QGSSMMGQRPMAPYRPSQQGSSQQYLGQ 249
           S+  G SQ Y   G S  A  G G         GS   G    +P  P   G  Q + GQ
Sbjct: 681 SATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQ 740

Query: 250 EE-YYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNS 308
           ++  YG  Y   QG  +   Q  Y + +G    +Q  Y       S+  S      GG S
Sbjct: 741 QKPSYGSGYQSHQGQQQSYNQSPYSN-YGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGS 799

Query: 309 QYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGS 368
            Y+ +      G+  +   +          PG   GYG   G  S Y G Q G  Q   +
Sbjct: 800 DYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQ--SN 857

Query: 369 YRAPQTA------PSAQQ--QRPYGYEQGQYGNYQ 395
           Y +P +       PS+ Q  Q  YG       NYQ
Sbjct: 858 YNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQ 892


>gi|171916097 repetin [Homo sapiens]
          Length = 784

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 72/267 (26%), Positives = 108/267 (40%), Gaps = 44/267 (16%)

Query: 156 GPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA--QGGSQHY----- 208
           G +S    M  QG  G++  +T+   QS+      +Q   SHY     QG S HY     
Sbjct: 410 GQSSHYSQMDRQGQ-GSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDR 468

Query: 209 QGQSSIAMM----GQGSQGSSMMGQRPMAPY-RPSQQGSSQQYLGQEEYYGEQYSHSQGA 263
           QGQSS        GQ S    +  Q     Y +P  QG S  Y GQ +  G+ + + Q  
Sbjct: 469 QGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHY-GQTDRQGQSFHYGQPD 527

Query: 264 AEPMGQQYYP-DGHGDYA-YQQSSYTEQS--YDRSFEESTQHYY-----EGGNSQYSQQQ 314
            +     Y   D  G  + Y Q+    QS  Y ++  +   ++Y     +G +S Y Q Q
Sbjct: 528 RQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQ 587

Query: 315 AGYQQG---------AAQQQTYSQQ---------QYPSQQSYPGQQQGYGSAQGAPSQYP 356
            G  QG           ++ +Y +Q         Q P Q+ Y  Q QG+   Q   SQ  
Sbjct: 588 TGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGF---QSRDSQQN 644

Query: 357 GYQQGQGQQYGSYRAPQTAPSAQQQRP 383
           G+Q  + ++   +   +     QQ+RP
Sbjct: 645 GHQVWEPEEDSQHHQHKLLAQIQQERP 671



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%)

Query: 165 QGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA--QGGSQHY-----QGQSS---- 213
           QGQG+   + S+ N   QS+       Q  +SHY     Q  S HY     QGQSS    
Sbjct: 361 QGQGS---HYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQ 417

Query: 214 IAMMGQGSQGSSMMGQRPMAPY-RPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQY- 271
           +   GQGS       Q   + Y +P +QG +  Y GQ +  G+   + Q   +     Y 
Sbjct: 418 MDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHY-GQTDRQGQSSHYGQTDRQGQSSHYS 476

Query: 272 YPDGHGDYA-YQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQT--YS 328
            PD  G  + Y +    +QSY     +        G +    Q   Y Q   Q Q+  YS
Sbjct: 477 QPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYS 536

Query: 329 QQQYPSQQSYPGQ--QQG----YGSAQGAPSQYPGYQQGQGQQYG-SYRAPQTAPSAQQQ 381
           Q     Q S+ GQ  +QG    YG            +QGQ   YG + R  Q++   Q Q
Sbjct: 537 QMDRQGQSSHYGQTDRQGQSSHYGQTD---------RQGQSYHYGQTDRQGQSSHYIQSQ 587

Query: 382 RPYGYEQGQYGNYQ 395
              G  QGQ   +Q
Sbjct: 588 T--GEIQGQNKYFQ 599



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 60/212 (28%), Positives = 82/212 (38%), Gaps = 26/212 (12%)

Query: 196 SHYSSA-QGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYG 254
           SH++   Q  S  Y GQS       G   +   GQ   + Y  + +     + GQ +  G
Sbjct: 257 SHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQS--SHYGQTDRQDQSYHYGQTDRQG 314

Query: 255 EQYSHSQGAAEPMGQQY-YPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQ- 312
           +   +SQ   +     Y  PD  G    Q S Y +           Q   +G  S YSQ 
Sbjct: 315 QSSHYSQTDRQGQSSHYSQPDRQG----QSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQP 370

Query: 313 ----QQAGYQQGAAQQQT--YSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGY-QQGQGQQ 365
               Q + Y Q   Q Q+  Y Q     Q S+ GQ +     QG  S Y    +QGQG  
Sbjct: 371 NRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTE----RQGQSSHYSQMDRQGQGSH 426

Query: 366 YG-SYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
           YG + R  Q++   Q  R     QGQ  +Y Q
Sbjct: 427 YGQTDRQGQSSHYGQPDR-----QGQNSHYGQ 453



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 59/228 (25%), Positives = 87/228 (38%), Gaps = 27/228 (11%)

Query: 166 GQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA--QGGSQHY-----QGQSS----I 214
           GQG   +Y  +T+   QS       +Q  +SHYS    QG S HY     QGQSS     
Sbjct: 504 GQGQSSHY-GQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQT 562

Query: 215 AMMGQGSQGSSMMGQRPMAPYRPSQ----QGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQ 270
              GQ         Q   + Y  SQ    QG ++ + G E      Y    G +  + QQ
Sbjct: 563 DRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQ 622

Query: 271 ------YYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQ 324
                 Y   G G  +        Q ++   EE +QH+     +Q  Q++    +G   Q
Sbjct: 623 TPGQEGYQNQGQGFQSRDSQQNGHQVWEP--EEDSQHHQHKLLAQIQQERPLCHKGRDWQ 680

Query: 325 QTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP 372
              S+Q +  +Q+   Q  G G +  A  +  G+Q      + S   P
Sbjct: 681 SCSSEQGH--RQAQTRQSHGEGLSHWAEEE-QGHQTWDRHSHESQEGP 725



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 35/168 (20%), Positives = 58/168 (34%), Gaps = 13/168 (7%)

Query: 236 RPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSF 295
           +P +Q     + GQ E       H Q   +     +      D     +    Q  D SF
Sbjct: 136 QPERQDGDSHH-GQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSF 194

Query: 296 EESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQ--QYPSQQSYPGQQQGYGSAQGAPS 353
           ++S +   +  + +    ++   Q   Q   ++    + P Q S+ GQ + +        
Sbjct: 195 DQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLG 254

Query: 354 QYPGYQQGQGQQYGSY-----RAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
           Q   + Q   Q+ GSY     R  Q     Q  R     QGQ  +Y Q
Sbjct: 255 QASHFNQTNQQKSGSYCGQSERLGQELGCGQTDR-----QGQSSHYGQ 297


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 60/190 (31%), Positives = 80/190 (42%), Gaps = 24/190 (12%)

Query: 196 SHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGE 255
           S+ +    GSQ Y GQ+S +  G G    S  GQ   + Y    Q  SQ Y G E    +
Sbjct: 16  SYSTYGNPGSQGY-GQASQSYSGYGQTTDSSYGQN-YSGYSSYGQSYSQSYGGYENQ--K 71

Query: 256 QYSHSQGAAEPMGQQYYPDGHG------------DYAYQQSSYTEQS-YDR---SFEEST 299
           Q S+SQ      GQQ   +  G            DY  QQ SY +QS YD+   S++E  
Sbjct: 72  QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG-QQDSYDQQSGYDQHQGSYDE-- 128

Query: 300 QHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGY- 358
           Q  Y+  +  YSQ Q  Y         ++Q        Y    +GYG +QG      GY 
Sbjct: 129 QSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYD 188

Query: 359 QQGQGQQYGS 368
           + G+G   GS
Sbjct: 189 KDGRGPMTGS 198



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 45/145 (31%), Positives = 59/145 (40%), Gaps = 22/145 (15%)

Query: 258 SHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNS---QYSQQQ 314
           S+ Q   E      Y +  G   Y Q+S +   Y ++ + S    Y G +S    YSQ  
Sbjct: 6   SYGQSGGEQQSYSTYGNP-GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64

Query: 315 AGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQT 374
            GY+    +Q +YSQQ Y +Q    GQQQ   S+     + P Y Q    Q  SY     
Sbjct: 65  GGYEN--QKQSSYSQQPYNNQ----GQQQNMESSGSQGGRAPSYDQPDYGQQDSY----- 113

Query: 375 APSAQQQRPYGYEQGQY---GNYQQ 396
                QQ  Y   QG Y    NY Q
Sbjct: 114 ----DQQSGYDQHQGSYDEQSNYDQ 134



 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 53/194 (27%), Positives = 73/194 (37%), Gaps = 46/194 (23%)

Query: 203 GGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQG 262
           GG Q    QS       GSQG     Q      + +     Q Y G    YG+ YS S G
Sbjct: 11  GGEQ----QSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS-YGQSYSQSYG 65

Query: 263 AAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA 322
             E                +QSSY++Q Y+                Q + + +G Q G A
Sbjct: 66  GYENQ--------------KQSSYSQQPYNNQ------------GQQQNMESSGSQGGRA 99

Query: 323 QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQR 382
              +Y Q  Y  Q SY  QQ GY   QG+  +   Y     QQ+ SY        +Q Q+
Sbjct: 100 --PSYDQPDYGQQDSY-DQQSGYDQHQGSYDEQSNYD----QQHDSY--------SQNQQ 144

Query: 383 PYGYEQGQYGNYQQ 396
            Y  ++  Y ++ Q
Sbjct: 145 SYHSQRENYSHHTQ 158


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
            sapiens]
          Length = 2191

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 78/322 (24%), Positives = 111/322 (34%), Gaps = 30/322 (9%)

Query: 76   PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQT 135
            P+P       GP     +GS+      G L        P   +   Q G   S +S+   
Sbjct: 1123 PSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQ-GGRSSTISVHDP 1181

Query: 136  APNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAAT 195
              +        +S   +      +   P Q   ++ + + R       +P   M++   +
Sbjct: 1182 FSD--------VSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGS 1233

Query: 196  SHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGE 255
            S     QG   +   Q        G+  +  MGQR   PY  S       Y  + E YG+
Sbjct: 1234 SEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS-------YDRRHEPYGQ 1286

Query: 256  QYSHSQGAAEPMGQQYYPDGHGDYAY-QQSSYTEQSYDRSFEESTQHYYEGGNSQY-SQQ 313
            QY    G   P GQ  Y  GH    Y QQ +Y           + +H  +  N QY SQQ
Sbjct: 1287 QY---PGQGPPSGQPPY-GGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQ 1342

Query: 314  QAGYQQGAAQQQTYSQQQYPSQQSYP---GQQQGYGSAQ--GAPSQYPGYQQGQGQQYGS 368
            Q  Y Q         ++    Q  YP    + QG G  Q  G P Q  G   G  Q   S
Sbjct: 1343 QEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMG---GPLQSSSS 1399

Query: 369  YRAPQTAPSAQQQRPYGYEQGQ 390
                Q   +A+   PY Y+  Q
Sbjct: 1400 EGPQQNMWAARNDMPYPYQNRQ 1421



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 61/228 (26%), Positives = 73/228 (32%), Gaps = 39/228 (17%)

Query: 200 SAQGGSQHYQGQS---------------SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244
           SA GG Q + GQ+               S + M +   GS      P AP  P  Q  SQ
Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398

Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQS-------------- 290
                    G+Q +   G  + MG QY        A QQ S+   S              
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458

Query: 291 -YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQ 349
             D    +  Q Y  G N     QQ+    G +          P  Q YP   QG     
Sbjct: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP-------PGPQRYPIGIQGRTPGA 511

Query: 350 GAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGY-EQGQYGNYQQ 396
            A  QYP  QQ  G            P   QQ   GY +QGQ   Y Q
Sbjct: 512 MAGMQYP-QQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQ 558



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 71/257 (27%), Positives = 95/257 (36%), Gaps = 60/257 (23%)

Query: 171 GNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG-------------------- 210
           G+Y   ++ +    P S  Q QAA +   +A GG Q   G                    
Sbjct: 377 GSYPEYSSPSAPPPPPSQPQSQAAAA--GAAAGGQQAAAGMGLGKDMGAQYAAASPAWAA 434

Query: 211 --QSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQY-LGQEEYYGEQYS--HSQGAAE 265
             Q S   M  G+ G +M G+   +P  P      Q Y +G   +   Q S  +  G+  
Sbjct: 435 AQQRSHPAMSPGTPGPTM-GRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493

Query: 266 PMGQQYYPDG-----HGDYAYQQSSYTEQSYDRSFEES----TQHYYEGGNSQYSQQQAG 316
           P G Q YP G      G  A  Q    + S D +++E+       Y + G S Y QQ   
Sbjct: 494 PPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQ--- 550

Query: 317 YQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ-YGSYRAPQTA 375
                 QQ  YSQQ  P     P Q Q Y  +Q      P  QQ   Q+ YG+   P  A
Sbjct: 551 -----GQQPYYSQQ--PQPPHLPPQAQ-YLPSQSQQRYQP--QQDMSQEGYGTRSQPPLA 600

Query: 376 PS---------AQQQRP 383
           P           QQ+RP
Sbjct: 601 PGKPNHEDLNLIQQERP 617



 Score = 36.2 bits (82), Expect = 0.053
 Identities = 73/303 (24%), Positives = 110/303 (36%), Gaps = 49/303 (16%)

Query: 74  LLPAPPT-QNMNL----GPGALTQ-SGSSQGLHS--QGSLSDAISTGLPPSSLLQGQIGN 125
           L P  P  +++NL     P +L   SGS   L +  + +LS A+S     SS  QG    
Sbjct: 599 LAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS--QGD--- 653

Query: 126 GPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNI-NMQSN 184
             S+ +    +P+  P  S    GP      P+  G P+    +    +S  +I   Q  
Sbjct: 654 -QSNPAQSPFSPHASPHLSSIPGGPS-----PSPVGSPVGSNQSRSGPISPASIPGSQMP 707

Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSS- 243
           P     Q  ++SH + +Q      +G  +      G+Q +  M Q     Y P Q G S 
Sbjct: 708 PQPPGSQSESSSHPALSQSPMPQERGFMA------GTQRNPQMAQ-----YGPQQTGPSM 756

Query: 244 --------QQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDY--AYQ---QSSYTEQS 290
                   Q + G   +   Q S+S G   P   QY P G+     AY     +SY+   
Sbjct: 757 SPHPSPGGQMHAGISSF---QQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 813

Query: 291 YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA-QQQTYSQQQYPSQQSYPGQQQGYGSAQ 349
                  + Q + +G +        G    A  Q + +         S PG  Q  G   
Sbjct: 814 PGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 873

Query: 350 GAP 352
           G P
Sbjct: 874 GPP 876



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 43/178 (24%), Positives = 59/178 (33%), Gaps = 22/178 (12%)

Query: 224  SSMMGQRPMAPYRPSQQGSSQ-QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQ 282
            SS   +  M P  P QQG S    +G+  Y   +        +P G      G  +    
Sbjct: 1188 SSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNK--------DPFGGMRKVPGSSEPFMT 1239

Query: 283  QSSYTEQSYDRSFEESTQHYYEGGNSQYSQ-QQAGYQQGAAQQQTYSQ--QQYPSQQSYP 339
            Q      S    + +S      G  S     Q+  +  GA+  + +    QQYP Q    
Sbjct: 1240 QGQMPNSSMQDMYNQSPS----GAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPS 1295

Query: 340  GQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391
            GQ    G   G   Q P Y++     YG               S+QQQ  Y    G Y
Sbjct: 1296 GQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSY 1353



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 281 YQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYP-SQQSYP 339
           +QQ  +   ++         H++     Q +Q Q   QQ   QQQ   QQQ+P S  +  
Sbjct: 23  HQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL 82

Query: 340 GQQQGYGSAQGAPSQYPGYQQGQ 362
           G     G+  GAP   P  +Q Q
Sbjct: 83  G-----GAGGGAPQPGPDMEQPQ 100



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 82/364 (22%), Positives = 119/364 (32%), Gaps = 53/364 (14%)

Query: 76  PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSD---------------------AISTGLP 114
           P PP+Q  +    A   +G  Q     G   D                     A+S G P
Sbjct: 389 PPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTP 448

Query: 115 PSSLLQGQIGNGPSHVSMQQ-------TAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQ 167
             ++ + Q G+    + M++       + P++ P  S    G  Y   GP    + +QG+
Sbjct: 449 GPTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGR 507

Query: 168 GTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMM 227
            T G          Q +  +  ++   T      Q G Q   G          SQ     
Sbjct: 508 -TPGAMAGMQYPQQQDSGDATWKE---TFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPP 563

Query: 228 GQRPMAPYRPSQQGSSQQYLGQEEYYGEQY-SHSQGAAEPMGQQYYPDGHGDYAYQQSSY 286
              P A Y PSQ  S Q+Y  Q++   E Y + SQ    P G+  + D +     + SS 
Sbjct: 564 HLPPQAQYLPSQ--SQQRYQPQQDMSQEGYGTRSQPPLAP-GKPNHEDLNLIQQERPSSL 620

Query: 287 TEQSYD-RSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPG--QQQ 343
            + S         T+       S      +   Q    Q  +S    P   S PG     
Sbjct: 621 PDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPS 680

Query: 344 GYGSAQG---------APSQYPGYQ---QGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391
             GS  G         +P+  PG Q   Q  G Q  S   P  + S   Q   G+  G  
Sbjct: 681 PVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQE-RGFMAGTQ 739

Query: 392 GNYQ 395
            N Q
Sbjct: 740 RNPQ 743



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 22/121 (18%)

Query: 70  NMQSLLPAPPTQNMNLGPG-----------------ALTQSGSSQGLHSQGSLSDAISTG 112
           NM S+ P+ P  +   GPG                 A+ Q+ ++     QGS      +G
Sbjct: 854 NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG 913

Query: 113 LPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQG-----VPMQGQ 167
           L  SS    Q  N  S +   Q  P ++    ++ S      A   S G     +P++  
Sbjct: 914 LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 973

Query: 168 G 168
           G
Sbjct: 974 G 974


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
            sapiens]
          Length = 2231

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 78/322 (24%), Positives = 111/322 (34%), Gaps = 30/322 (9%)

Query: 76   PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQT 135
            P+P       GP     +GS+      G L        P   +   Q G   S +S+   
Sbjct: 1163 PSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQ-GGRSSTISVHDP 1221

Query: 136  APNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAAT 195
              +        +S   +      +   P Q   ++ + + R       +P   M++   +
Sbjct: 1222 FSD--------VSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGS 1273

Query: 196  SHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGE 255
            S     QG   +   Q        G+  +  MGQR   PY  S       Y  + E YG+
Sbjct: 1274 SEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS-------YDRRHEPYGQ 1326

Query: 256  QYSHSQGAAEPMGQQYYPDGHGDYAY-QQSSYTEQSYDRSFEESTQHYYEGGNSQY-SQQ 313
            QY    G   P GQ  Y  GH    Y QQ +Y           + +H  +  N QY SQQ
Sbjct: 1327 QY---PGQGPPSGQPPY-GGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQ 1382

Query: 314  QAGYQQGAAQQQTYSQQQYPSQQSYP---GQQQGYGSAQ--GAPSQYPGYQQGQGQQYGS 368
            Q  Y Q         ++    Q  YP    + QG G  Q  G P Q  G   G  Q   S
Sbjct: 1383 QEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMG---GPLQSSSS 1439

Query: 369  YRAPQTAPSAQQQRPYGYEQGQ 390
                Q   +A+   PY Y+  Q
Sbjct: 1440 EGPQQNMWAARNDMPYPYQNRQ 1461



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 59/221 (26%), Positives = 73/221 (33%), Gaps = 41/221 (18%)

Query: 200 SAQGGSQHYQGQS---------------SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244
           SA GG Q + GQ+               S + M +   GS      P AP  P  Q  SQ
Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398

Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQS-------------- 290
                    G+Q +   G  + MG QY        A QQ S+   S              
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458

Query: 291 -YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQ 349
             D    +  Q Y  G N     QQ+    G +          P  Q YP   QG     
Sbjct: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP-------PGPQRYPIGIQGRTPGA 511

Query: 350 GAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQ 390
            A  QYP  QQ    QYG      +    Q Q+PY  +Q Q
Sbjct: 512 MAGMQYP--QQQMPPQYGQQGV--SGYCQQGQQPYYSQQPQ 548



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 68/251 (27%), Positives = 89/251 (35%), Gaps = 61/251 (24%)

Query: 171 GNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG-------------------- 210
           G+Y   ++ +    P S  Q QAA +   +A GG Q   G                    
Sbjct: 377 GSYPEYSSPSAPPPPPSQPQSQAAAA--GAAAGGQQAAAGMGLGKDMGAQYAAASPAWAA 434

Query: 211 --QSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQY-LGQEEYYGEQYS--HSQGAAE 265
             Q S   M  G+ G +M G+   +P  P      Q Y +G   +   Q S  +  G+  
Sbjct: 435 AQQRSHPAMSPGTPGPTM-GRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493

Query: 266 PMGQQYYP---DGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA 322
           P G Q YP    G    A     Y +Q       +    Y + G S Y QQ         
Sbjct: 494 PPGPQRYPIGIQGRTPGAMAGMQYPQQ-------QMPPQYGQQGVSGYCQQ--------G 538

Query: 323 QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ-YGSYRAPQTAPS---- 377
           QQ  YSQQ  P     P Q Q Y  +Q      P  QQ   Q+ YG+   P  AP     
Sbjct: 539 QQPYYSQQ--PQPPHLPPQAQ-YLPSQSQQRYQP--QQDMSQEGYGTRSQPPLAPGKPNH 593

Query: 378 -----AQQQRP 383
                 QQ+RP
Sbjct: 594 EDLNLIQQERP 604



 Score = 36.2 bits (82), Expect = 0.053
 Identities = 81/409 (19%), Positives = 126/409 (30%), Gaps = 101/409 (24%)

Query: 76  PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSD---------------------AISTGLP 114
           P PP+Q  +    A   +G  Q     G   D                     A+S G P
Sbjct: 389 PPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTP 448

Query: 115 PSSLLQGQIGNGPSHVSMQQ-------TAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQ 167
             ++ + Q G+    + M++       + P++ P  S    G  Y   GP    + +QG+
Sbjct: 449 GPTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGR 507

Query: 168 GTIGNYVSRTNINMQSNP------VSMMQQQAATSHYSS--------------AQGGSQH 207
            T G          Q  P      VS   QQ    +YS                    Q 
Sbjct: 508 -TPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQR 566

Query: 208 YQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ--------------------------- 240
           YQ Q  ++  G G++      Q P+AP +P+ +                           
Sbjct: 567 YQPQQDMSQEGYGTR-----SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGT 621

Query: 241 ----GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQY---YPDGHGDYAYQQSSYTEQSYDR 293
                S+    G     G+Q + +Q    P    +    P G           + QS   
Sbjct: 622 EATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSG 681

Query: 294 SFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPG------QQQGYGS 347
               ++        SQ   Q  G Q  ++     SQ   P ++ +        Q   YG 
Sbjct: 682 PISPASI-----PGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGP 736

Query: 348 AQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
            Q  PS  P    G GQ +    + Q + S+    P   + G  GNY +
Sbjct: 737 QQTGPSMSPHPSPG-GQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSR 784



 Score = 36.2 bits (82), Expect = 0.053
 Identities = 73/303 (24%), Positives = 110/303 (36%), Gaps = 49/303 (16%)

Query: 74  LLPAPPT-QNMNL----GPGALTQ-SGSSQGLHS--QGSLSDAISTGLPPSSLLQGQIGN 125
           L P  P  +++NL     P +L   SGS   L +  + +LS A+S     SS  QG    
Sbjct: 586 LAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS--QGD--- 640

Query: 126 GPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNI-NMQSN 184
             S+ +    +P+  P  S    GP      P+  G P+    +    +S  +I   Q  
Sbjct: 641 -QSNPAQSPFSPHASPHLSSIPGGPS-----PSPVGSPVGSNQSRSGPISPASIPGSQMP 694

Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSS- 243
           P     Q  ++SH + +Q      +G  +      G+Q +  M Q     Y P Q G S 
Sbjct: 695 PQPPGSQSESSSHPALSQSPMPQERGFMA------GTQRNPQMAQ-----YGPQQTGPSM 743

Query: 244 --------QQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDY--AYQ---QSSYTEQS 290
                   Q + G   +   Q S+S G   P   QY P G+     AY     +SY+   
Sbjct: 744 SPHPSPGGQMHAGISSF---QQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 800

Query: 291 YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA-QQQTYSQQQYPSQQSYPGQQQGYGSAQ 349
                  + Q + +G +        G    A  Q + +         S PG  Q  G   
Sbjct: 801 PGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860

Query: 350 GAP 352
           G P
Sbjct: 861 GPP 863



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 43/178 (24%), Positives = 59/178 (33%), Gaps = 22/178 (12%)

Query: 224  SSMMGQRPMAPYRPSQQGSSQ-QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQ 282
            SS   +  M P  P QQG S    +G+  Y   +        +P G      G  +    
Sbjct: 1228 SSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNK--------DPFGGMRKVPGSSEPFMT 1279

Query: 283  QSSYTEQSYDRSFEESTQHYYEGGNSQYSQ-QQAGYQQGAAQQQTYSQ--QQYPSQQSYP 339
            Q      S    + +S      G  S     Q+  +  GA+  + +    QQYP Q    
Sbjct: 1280 QGQMPNSSMQDMYNQSPS----GAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPS 1335

Query: 340  GQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391
            GQ    G   G   Q P Y++     YG               S+QQQ  Y    G Y
Sbjct: 1336 GQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSY 1393



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 281 YQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYP-SQQSYP 339
           +QQ  +   ++         H++     Q +Q Q   QQ   QQQ   QQQ+P S  +  
Sbjct: 23  HQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL 82

Query: 340 GQQQGYGSAQGAPSQYPGYQQGQ 362
           G     G+  GAP   P  +Q Q
Sbjct: 83  G-----GAGGGAPQPGPDMEQPQ 100



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 22/121 (18%)

Query: 70  NMQSLLPAPPTQNMNLGPG-----------------ALTQSGSSQGLHSQGSLSDAISTG 112
           NM S+ P+ P  +   GPG                 A+ Q+ ++     QGS      +G
Sbjct: 841 NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG 900

Query: 113 LPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQG-----VPMQGQ 167
           L  SS    Q  N  S +   Q  P ++    ++ S      A   S G     +P++  
Sbjct: 901 LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960

Query: 168 G 168
           G
Sbjct: 961 G 961


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
            sapiens]
          Length = 2178

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 78/322 (24%), Positives = 111/322 (34%), Gaps = 30/322 (9%)

Query: 76   PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQT 135
            P+P       GP     +GS+      G L        P   +   Q G   S +S+   
Sbjct: 1110 PSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQ-GGRSSTISVHDP 1168

Query: 136  APNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAAT 195
              +        +S   +      +   P Q   ++ + + R       +P   M++   +
Sbjct: 1169 FSD--------VSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGS 1220

Query: 196  SHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGE 255
            S     QG   +   Q        G+  +  MGQR   PY  S       Y  + E YG+
Sbjct: 1221 SEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS-------YDRRHEPYGQ 1273

Query: 256  QYSHSQGAAEPMGQQYYPDGHGDYAY-QQSSYTEQSYDRSFEESTQHYYEGGNSQY-SQQ 313
            QY    G   P GQ  Y  GH    Y QQ +Y           + +H  +  N QY SQQ
Sbjct: 1274 QY---PGQGPPSGQPPY-GGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQ 1329

Query: 314  QAGYQQGAAQQQTYSQQQYPSQQSYP---GQQQGYGSAQ--GAPSQYPGYQQGQGQQYGS 368
            Q  Y Q         ++    Q  YP    + QG G  Q  G P Q  G   G  Q   S
Sbjct: 1330 QEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMG---GPLQSSSS 1386

Query: 369  YRAPQTAPSAQQQRPYGYEQGQ 390
                Q   +A+   PY Y+  Q
Sbjct: 1387 EGPQQNMWAARNDMPYPYQNRQ 1408



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 59/221 (26%), Positives = 73/221 (33%), Gaps = 41/221 (18%)

Query: 200 SAQGGSQHYQGQS---------------SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244
           SA GG Q + GQ+               S + M +   GS      P AP  P  Q  SQ
Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398

Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQS-------------- 290
                    G+Q +   G  + MG QY        A QQ S+   S              
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458

Query: 291 -YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQ 349
             D    +  Q Y  G N     QQ+    G +          P  Q YP   QG     
Sbjct: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP-------PGPQRYPIGIQGRTPGA 511

Query: 350 GAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQ 390
            A  QYP  QQ    QYG      +    Q Q+PY  +Q Q
Sbjct: 512 MAGMQYP--QQQMPPQYGQQGV--SGYCQQGQQPYYSQQPQ 548



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 68/251 (27%), Positives = 89/251 (35%), Gaps = 61/251 (24%)

Query: 171 GNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG-------------------- 210
           G+Y   ++ +    P S  Q QAA +   +A GG Q   G                    
Sbjct: 377 GSYPEYSSPSAPPPPPSQPQSQAAAA--GAAAGGQQAAAGMGLGKDMGAQYAAASPAWAA 434

Query: 211 --QSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQY-LGQEEYYGEQYS--HSQGAAE 265
             Q S   M  G+ G +M G+   +P  P      Q Y +G   +   Q S  +  G+  
Sbjct: 435 AQQRSHPAMSPGTPGPTM-GRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493

Query: 266 PMGQQYYP---DGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA 322
           P G Q YP    G    A     Y +Q       +    Y + G S Y QQ         
Sbjct: 494 PPGPQRYPIGIQGRTPGAMAGMQYPQQ-------QMPPQYGQQGVSGYCQQ--------G 538

Query: 323 QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ-YGSYRAPQTAPS---- 377
           QQ  YSQQ  P     P Q Q Y  +Q      P  QQ   Q+ YG+   P  AP     
Sbjct: 539 QQPYYSQQ--PQPPHLPPQAQ-YLPSQSQQRYQP--QQDMSQEGYGTRSQPPLAPGKPNH 593

Query: 378 -----AQQQRP 383
                 QQ+RP
Sbjct: 594 EDLNLIQQERP 604



 Score = 36.2 bits (82), Expect = 0.053
 Identities = 81/409 (19%), Positives = 126/409 (30%), Gaps = 101/409 (24%)

Query: 76  PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSD---------------------AISTGLP 114
           P PP+Q  +    A   +G  Q     G   D                     A+S G P
Sbjct: 389 PPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTP 448

Query: 115 PSSLLQGQIGNGPSHVSMQQ-------TAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQ 167
             ++ + Q G+    + M++       + P++ P  S    G  Y   GP    + +QG+
Sbjct: 449 GPTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGR 507

Query: 168 GTIGNYVSRTNINMQSNP------VSMMQQQAATSHYSS--------------AQGGSQH 207
            T G          Q  P      VS   QQ    +YS                    Q 
Sbjct: 508 -TPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQR 566

Query: 208 YQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ--------------------------- 240
           YQ Q  ++  G G++      Q P+AP +P+ +                           
Sbjct: 567 YQPQQDMSQEGYGTR-----SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGT 621

Query: 241 ----GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQY---YPDGHGDYAYQQSSYTEQSYDR 293
                S+    G     G+Q + +Q    P    +    P G           + QS   
Sbjct: 622 EATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSG 681

Query: 294 SFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPG------QQQGYGS 347
               ++        SQ   Q  G Q  ++     SQ   P ++ +        Q   YG 
Sbjct: 682 PISPASI-----PGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGP 736

Query: 348 AQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
            Q  PS  P    G GQ +    + Q + S+    P   + G  GNY +
Sbjct: 737 QQTGPSMSPHPSPG-GQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSR 784



 Score = 36.2 bits (82), Expect = 0.053
 Identities = 73/303 (24%), Positives = 110/303 (36%), Gaps = 49/303 (16%)

Query: 74  LLPAPPT-QNMNL----GPGALTQ-SGSSQGLHS--QGSLSDAISTGLPPSSLLQGQIGN 125
           L P  P  +++NL     P +L   SGS   L +  + +LS A+S     SS  QG    
Sbjct: 586 LAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS--QGD--- 640

Query: 126 GPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNI-NMQSN 184
             S+ +    +P+  P  S    GP      P+  G P+    +    +S  +I   Q  
Sbjct: 641 -QSNPAQSPFSPHASPHLSSIPGGPS-----PSPVGSPVGSNQSRSGPISPASIPGSQMP 694

Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSS- 243
           P     Q  ++SH + +Q      +G  +      G+Q +  M Q     Y P Q G S 
Sbjct: 695 PQPPGSQSESSSHPALSQSPMPQERGFMA------GTQRNPQMAQ-----YGPQQTGPSM 743

Query: 244 --------QQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDY--AYQ---QSSYTEQS 290
                   Q + G   +   Q S+S G   P   QY P G+     AY     +SY+   
Sbjct: 744 SPHPSPGGQMHAGISSF---QQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 800

Query: 291 YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA-QQQTYSQQQYPSQQSYPGQQQGYGSAQ 349
                  + Q + +G +        G    A  Q + +         S PG  Q  G   
Sbjct: 801 PGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860

Query: 350 GAP 352
           G P
Sbjct: 861 GPP 863



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 43/178 (24%), Positives = 59/178 (33%), Gaps = 22/178 (12%)

Query: 224  SSMMGQRPMAPYRPSQQGSSQ-QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQ 282
            SS   +  M P  P QQG S    +G+  Y   +        +P G      G  +    
Sbjct: 1175 SSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNK--------DPFGGMRKVPGSSEPFMT 1226

Query: 283  QSSYTEQSYDRSFEESTQHYYEGGNSQYSQ-QQAGYQQGAAQQQTYSQ--QQYPSQQSYP 339
            Q      S    + +S      G  S     Q+  +  GA+  + +    QQYP Q    
Sbjct: 1227 QGQMPNSSMQDMYNQSPS----GAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPS 1282

Query: 340  GQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391
            GQ    G   G   Q P Y++     YG               S+QQQ  Y    G Y
Sbjct: 1283 GQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSY 1340



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 281 YQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYP-SQQSYP 339
           +QQ  +   ++         H++     Q +Q Q   QQ   QQQ   QQQ+P S  +  
Sbjct: 23  HQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL 82

Query: 340 GQQQGYGSAQGAPSQYPGYQQGQ 362
           G     G+  GAP   P  +Q Q
Sbjct: 83  G-----GAGGGAPQPGPDMEQPQ 100



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 22/121 (18%)

Query: 70  NMQSLLPAPPTQNMNLGPG-----------------ALTQSGSSQGLHSQGSLSDAISTG 112
           NM S+ P+ P  +   GPG                 A+ Q+ ++     QGS      +G
Sbjct: 841 NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG 900

Query: 113 LPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQG-----VPMQGQ 167
           L  SS    Q  N  S +   Q  P ++    ++ S      A   S G     +P++  
Sbjct: 901 LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960

Query: 168 G 168
           G
Sbjct: 961 G 961


>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
           sapiens]
          Length = 600

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 53/215 (24%), Positives = 76/215 (35%), Gaps = 12/215 (5%)

Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240
           M S   S   Q AA   YS+    +Q  QG +       G Q     GQ     Y  +Q 
Sbjct: 1   MASTDYSTYSQAAAQQGYSAYT--AQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQT 57

Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300
            ++         YG+  +       P        G+G  AY  ++ T  +   S+   + 
Sbjct: 58  TATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSA 117

Query: 301 HYYEGGNSQYSQQQAGY---QQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357
           +  +     Y QQ A        + Q  +Y Q  Y  Q +Y     G  S+ G  S Y G
Sbjct: 118 YGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTY-----GQPSSYGQQSSY-G 171

Query: 358 YQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYG 392
            Q   GQQ  +   PQT   +Q    Y  +   YG
Sbjct: 172 QQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYG 206



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 59/258 (22%), Positives = 88/258 (34%), Gaps = 21/258 (8%)

Query: 142 TTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA 201
           T S + +  GYS    A    P QG         + +      P  +   QA T+    A
Sbjct: 8   TYSQAAAQQGYS----AYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTT----A 59

Query: 202 QGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLG--QEEYYGEQYSH 259
             G   Y         G  +  +     +P+  Y      ++   +   Q  Y  +    
Sbjct: 60  TYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG 119

Query: 260 SQGAAEPMGQQYYPDGHGDYAYQQ-SSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQ 318
           +Q A    GQQ        Y+  Q +SY + SY +         Y G  S Y QQ +  Q
Sbjct: 120 TQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSY-GQQSSYGQQSSYGQ 178

Query: 319 QGAAQ--QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP---- 372
           Q       QT S  Q PSQ  Y  Q   YG        +P      GQ+ G +  P    
Sbjct: 179 QPPTSYPPQTGSYSQAPSQ--YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENR 236

Query: 373 -QTAPSAQQQRPYGYEQG 389
             + P  + +   G+++G
Sbjct: 237 SMSGPDNRGRGRGGFDRG 254


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 87/327 (26%), Positives = 116/327 (35%), Gaps = 54/327 (16%)

Query: 69  QNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPS 128
           Q   S   A PTQ    G    TQ+   Q   + G  +D +S     ++   GQ     S
Sbjct: 15  QQGYSAYTAQPTQ----GYAQTTQAYGQQSYGTYGQPTD-VSYTQAQTTATYGQTAYATS 69

Query: 129 HVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSM 188
           +       P T+  TS   + P      P +   P+QG GT G Y + T     +   + 
Sbjct: 70  YGQ-----PPTVEGTSTGYTTP----TAPQAYSQPVQGYGT-GAYDTTT-----ATVTTT 114

Query: 189 MQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLG 248
               AA S Y +              A    G Q ++    RP    +P++    Q   G
Sbjct: 115 QASYAAQSAYGTQP------------AYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTG 162

Query: 249 QEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNS 308
                   Y  S  +        YP   G Y  Q  +        S+  +    Y+   S
Sbjct: 163 GYNQPSLGYGQSNYS--------YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYD--QS 212

Query: 309 QYSQQQA-GYQQGAAQQQTYSQQQYPSQQ---SYPGQQQGYGSAQGAPSQYPGYQQGQGQ 364
            YSQQ   G      QQ +Y QQ    QQ   SYP Q    GS   APSQY       GQ
Sbjct: 213 SYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQT---GSYSQAPSQYSQQSSSYGQ 269

Query: 365 QYGSYRAPQTAPSAQQQRPYGYEQGQY 391
           Q  S+R  Q  PS+     YG E G +
Sbjct: 270 Q-SSFR--QDHPSS--MGVYGQESGGF 291



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 14/114 (12%)

Query: 278 DYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQS 337
           DY+    +  +Q Y     + TQ Y +     Y QQ  G   G     +Y+Q Q  +   
Sbjct: 5   DYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYG-TYGQPTDVSYTQAQTTATYG 62

Query: 338 YPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391
               Q  Y ++ G P    G   G       Y  P TAP A  Q   GY  G Y
Sbjct: 63  ----QTAYATSYGQPPTVEGTSTG-------YTTP-TAPQAYSQPVQGYGTGAY 104



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 39/170 (22%), Positives = 53/170 (31%), Gaps = 37/170 (21%)

Query: 258 SHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY 317
           ++SQ AA+     Y       YA    +Y +QSY  ++ + T   Y    +  +  Q  Y
Sbjct: 8   TYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYG-TYGQPTDVSYTQAQTTATYGQTAY 66

Query: 318 QQGAAQQQT-------YSQQQYPSQQSYPGQQQGYG-------------------SAQGA 351
                Q  T       Y+    P   S P Q  G G                   SA G 
Sbjct: 67  ATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 126

Query: 352 PSQYPGYQQ----------GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391
              YP Y Q            G +      PQ++     Q   GY Q  Y
Sbjct: 127 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNY 176


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 53/156 (33%), Positives = 61/156 (39%), Gaps = 27/156 (17%)

Query: 253 YGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSS--YTEQSYDRSFEESTQHYYEGGNSQY 310
           Y +Q + S GA        YP   G    QQSS  Y +QSY    + +    Y  G S Y
Sbjct: 6   YTQQATQSYGA--------YPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY--GQSSY 55

Query: 311 SQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ---------- 360
           S        G   Q T   Q Y S   Y G  Q   S+ G  S YPGY Q          
Sbjct: 56  SSYGQSQNTGYGTQST--PQGYGSTGGY-GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGS 112

Query: 361 -GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQ 395
            G   Q  SY  PQ+  S  QQ  YG +Q  YG  Q
Sbjct: 113 YGSSSQSSSYGQPQSG-SYSQQPSYGGQQQSYGQQQ 147



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 70/255 (27%), Positives = 84/255 (32%), Gaps = 49/255 (19%)

Query: 122 QIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINM 181
           Q G G S  S Q     +    S S    GY  +  +S G   Q Q T            
Sbjct: 20  QPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYG---QSQNT--------GYGT 68

Query: 182 QSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMG----QRPMAPYRP 237
           QS P    Q   +T  Y S+Q     Y  QSS    GQ    SS  G        + Y  
Sbjct: 69  QSTP----QGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQ 124

Query: 238 SQQGSSQQ---YLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRS 294
            Q GS  Q   Y GQ++ YG+Q S++            P G+G    QQ+ Y   S    
Sbjct: 125 PQSGSYSQQPSYGGQQQSYGQQQSYNP-----------PQGYG----QQNQYNSSSGGGG 169

Query: 295 FEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQ 354
                     GG   Y Q Q+    G      Y  Q     QS  G   GYG        
Sbjct: 170 --------GGGGGGNYGQDQSSMSSGGGSGGGYGNQ----DQSGGGGSGGYGQQDRGGRG 217

Query: 355 YPGYQQGQGQQYGSY 369
             G   G G   G Y
Sbjct: 218 RGGSGGGGGGGGGGY 232



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 62/200 (31%), Positives = 74/200 (37%), Gaps = 19/200 (9%)

Query: 196 SHYSSAQGGSQHYQGQS-SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYG 254
           S  SS   G Q Y G S S    G G    S  GQ     Y    Q + Q Y G    YG
Sbjct: 26  SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGY--GTQSTPQGY-GSTGGYG 82

Query: 255 EQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQ 314
                SQ +    GQQ    G+G      S  T  SY  S + S+  Y +  +  YSQQ 
Sbjct: 83  S----SQSSQSSYGQQSSYPGYGQQPAPSS--TSGSYGSSSQSSS--YGQPQSGSYSQQP 134

Query: 315 A--GYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP 372
           +  G QQ   QQQ+Y+  Q   QQ+      G G   G    Y     GQ Q   S    
Sbjct: 135 SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY-----GQDQSSMSSGGG 189

Query: 373 QTAPSAQQQRPYGYEQGQYG 392
                  Q +  G   G YG
Sbjct: 190 SGGGYGNQDQSGGGGSGGYG 209



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 52/166 (31%), Positives = 68/166 (40%), Gaps = 22/166 (13%)

Query: 240 QGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEEST 299
           Q ++Q Y       G+ YS  Q +++P GQQ Y        Y QS+ T      S+    
Sbjct: 8   QQATQSYGAYPTQPGQGYS--QQSSQPYGQQSYS------GYSQSTDTSGYGQSSYSSYG 59

Query: 300 QHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQ---------GYGSAQG 350
           Q    G  +Q + Q  G   G    Q+ SQ  Y  Q SYPG  Q          YGS+  
Sbjct: 60  QSQNTGYGTQSTPQGYGSTGGYGSSQS-SQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQ 118

Query: 351 APSQYPGYQQGQGQQYGSYRAPQTAPSAQQ--QRPYGY-EQGQYGN 393
           + S Y   Q G   Q  SY   Q +   QQ    P GY +Q QY +
Sbjct: 119 S-SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNS 163



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 34/96 (35%), Positives = 38/96 (39%), Gaps = 13/96 (13%)

Query: 313 QQAGYQQGAAQQQT---YSQQ--QYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYG 367
           QQA    GA   Q    YSQQ  Q   QQSY G  Q   ++    S Y  Y Q Q   YG
Sbjct: 8   QQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYG 67

Query: 368 SYRAPQ-------TAPSAQQQRPYGYEQGQYGNYQQ 396
           +   PQ          S   Q  YG +Q  Y  Y Q
Sbjct: 68  TQSTPQGYGSTGGYGSSQSSQSSYG-QQSSYPGYGQ 102


>gi|93141033 PAX interacting protein 1 [Homo sapiens]
          Length = 1069

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 79/316 (25%), Positives = 111/316 (35%), Gaps = 23/316 (7%)

Query: 78  PPTQNMNLGP---GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQ 134
           PP     L P   G L  +G  Q L S    S+ I+T  P    L+    N       Q 
Sbjct: 297 PPVPGNILPPEVRGNLMAAG--QNLQSS-ERSEMIATWSPAVRTLRNITNNADIQ---QM 350

Query: 135 TAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQG-TIGNYVSRTNINMQSNPVSMMQQQA 193
             P+ +     ++S P  +      Q V    QG T  N V  + + +   P + M QQ 
Sbjct: 351 NRPSNVAHILQTLSAPTKN----LEQQVNHSQQGHTNANAVLFSQVKV--TPETHMLQQQ 404

Query: 194 ATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYY 253
             +     Q    H Q Q  + +  Q  Q  S        P+  SQQ   QQ     ++ 
Sbjct: 405 QQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFS 464

Query: 254 GEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQ 313
            +Q    Q    P  Q + P        QQ +  +Q +     +  Q        Q+S  
Sbjct: 465 QQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLL 524

Query: 314 QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGS--AQGAPSQYPGYQQGQGQQYGSYRA 371
           Q   QQ   QQQ     Q   QQ    Q   + S  +Q    Q P  Q  Q QQ      
Sbjct: 525 QQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQ-----Q 579

Query: 372 PQTAPSAQQQRPYGYE 387
            Q  PS QQ + +G++
Sbjct: 580 QQPPPSPQQHQLFGHD 595



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 43/162 (26%), Positives = 60/162 (37%), Gaps = 7/162 (4%)

Query: 238 SQQGSSQQ---YLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRS 294
           SQQG +        Q +   E +   Q       QQ +P  H     Q     +    + 
Sbjct: 377 SQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLH----LQPQQIMQLQQQQQ 432

Query: 295 FEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQ 354
            + S Q Y +     +SQQQ   QQ    Q +  Q Q+P QQ +P QQ      Q  P Q
Sbjct: 433 QQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQ 492

Query: 355 YPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
                Q Q  Q   ++  Q   +  QQ+    +Q Q    QQ
Sbjct: 493 QQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQ 534


>gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
          Length = 1938

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 86/343 (25%), Positives = 116/343 (33%), Gaps = 64/343 (18%)

Query: 81  QNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTL 140
           QN     G+   SGS  G   +G+ + A +     S   QG  G           A N  
Sbjct: 39  QNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGH-QGYQGFRKEAGDFYYMAGNKD 97

Query: 141 PTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSS 200
           P T+ +   P    +GP     P QG      Y S  ++       S +      SHY  
Sbjct: 98  PVTTGTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGL---GGVSHYQQ 154

Query: 201 ------AQGGSQHYQGQSSIAMMGQGSQGSSMMGQR----PMAPYRPSQQGSSQQYL--- 247
                 + G +Q+ Q  SS     Q  Q    + Q     P A  +P+   S  Q +   
Sbjct: 155 DYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRP 214

Query: 248 --------GQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEEST 299
                   G +   G+   H Q +A       +P        Q+ S + QSYD S+  + 
Sbjct: 215 STLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSP------QRFSQSGQSYDGSYNVNA 268

Query: 300 QHYYEGGN-----------SQYSQQ--------QAGYQQGAAQQQTYSQQQYPSQQSYPG 340
              YEG N           S YS Q        QA   QG  Q Q   QQQ P QQ +P 
Sbjct: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQ---QQQQPQQQQHPS 325

Query: 341 Q--QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQ 381
           Q   Q   +A   P Q          Q G Y  P+    +  Q
Sbjct: 326 QHVMQYTNAATKLPLQ---------SQVGQYNQPEVPVRSPMQ 359



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 54/205 (26%), Positives = 74/205 (36%), Gaps = 33/205 (16%)

Query: 193 AATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEY 252
           AA +  +S   G Q YQG        +      M G +      P   G+ Q    +   
Sbjct: 64  AAAAAMASETSGHQGYQG-----FRKEAGDFYYMAGNKD-----PVTTGTPQPPQRRPSG 113

Query: 253 YGEQYSHSQGAAEPMGQQYYPDGH-GDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYS 311
             + Y   QG++   G QY  +GH G +  Q S     S          HY +     +S
Sbjct: 114 PVQSYGPPQGSS--FGNQYGSEGHVGQFQAQHSGLGGVS----------HYQQDYTGPFS 161

Query: 312 QQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRA 371
              A YQQ A+ QQ   Q Q   QQ Y   Q     A G P+    + Q         + 
Sbjct: 162 PGSAQYQQQASSQQQQQQVQQLRQQLYQSHQP-LPQATGQPASSSSHLQ-------PMQR 213

Query: 372 PQTAPSAQQQRPYGYEQGQYGNYQQ 396
           P T PS+     Y    GQ+G + Q
Sbjct: 214 PSTLPSS--AAGYQLRVGQFGQHYQ 236



 Score = 35.4 bits (80), Expect = 0.091
 Identities = 56/290 (19%), Positives = 104/290 (35%), Gaps = 46/290 (15%)

Query: 63  TIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQ 122
           T ++ +   +  L +P  ++++   G  + S   QG   +     + S+          +
Sbjct: 499 TNSEGSSQPEEQLKSPMAESLD---GGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEK 555

Query: 123 IGNGPSHVSMQQTAP-NTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNI-- 179
            G+ P+  +  +    N  P      + PG      +S G P   + T+G  VSR  +  
Sbjct: 556 AGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTG 615

Query: 180 -----------NMQSNPVSMMQQQA-----ATSHYSSAQ---------GGSQHYQGQSSI 214
                      + + +P +  +  +      TSH S  Q          G+++    S+ 
Sbjct: 616 RVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNH 675

Query: 215 AMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEP---MGQQY 271
              G G  G S  G    +   PS+   S +Y          Y  S G+A P    G   
Sbjct: 676 NGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRY---------SYKDSFGSAVPRNVSGFPQ 726

Query: 272 YPDGH--GDY-AYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQ 318
           YP G   GD+  + +     + +    +E  Q Y+   + +YS+    +Q
Sbjct: 727 YPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQ 776


>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
          Length = 1960

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 86/343 (25%), Positives = 116/343 (33%), Gaps = 64/343 (18%)

Query: 81  QNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTL 140
           QN     G+   SGS  G   +G+ + A +     S   QG  G           A N  
Sbjct: 39  QNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGH-QGYQGFRKEAGDFYYMAGNKD 97

Query: 141 PTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSS 200
           P T+ +   P    +GP     P QG      Y S  ++       S +      SHY  
Sbjct: 98  PVTTGTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGL---GGVSHYQQ 154

Query: 201 ------AQGGSQHYQGQSSIAMMGQGSQGSSMMGQR----PMAPYRPSQQGSSQQYL--- 247
                 + G +Q+ Q  SS     Q  Q    + Q     P A  +P+   S  Q +   
Sbjct: 155 DYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRP 214

Query: 248 --------GQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEEST 299
                   G +   G+   H Q +A       +P        Q+ S + QSYD S+  + 
Sbjct: 215 STLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSP------QRFSQSGQSYDGSYNVNA 268

Query: 300 QHYYEGGN-----------SQYSQQ--------QAGYQQGAAQQQTYSQQQYPSQQSYPG 340
              YEG N           S YS Q        QA   QG  Q Q   QQQ P QQ +P 
Sbjct: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQ---QQQQPQQQQHPS 325

Query: 341 Q--QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQ 381
           Q   Q   +A   P Q          Q G Y  P+    +  Q
Sbjct: 326 QHVMQYTNAATKLPLQ---------SQVGQYNQPEVPVRSPMQ 359



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 54/205 (26%), Positives = 74/205 (36%), Gaps = 33/205 (16%)

Query: 193 AATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEY 252
           AA +  +S   G Q YQG        +      M G +      P   G+ Q    +   
Sbjct: 64  AAAAAMASETSGHQGYQG-----FRKEAGDFYYMAGNKD-----PVTTGTPQPPQRRPSG 113

Query: 253 YGEQYSHSQGAAEPMGQQYYPDGH-GDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYS 311
             + Y   QG++   G QY  +GH G +  Q S     S          HY +     +S
Sbjct: 114 PVQSYGPPQGSS--FGNQYGSEGHVGQFQAQHSGLGGVS----------HYQQDYTGPFS 161

Query: 312 QQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRA 371
              A YQQ A+ QQ   Q Q   QQ Y   Q     A G P+    + Q         + 
Sbjct: 162 PGSAQYQQQASSQQQQQQVQQLRQQLYQSHQP-LPQATGQPASSSSHLQ-------PMQR 213

Query: 372 PQTAPSAQQQRPYGYEQGQYGNYQQ 396
           P T PS+     Y    GQ+G + Q
Sbjct: 214 PSTLPSS--AAGYQLRVGQFGQHYQ 236



 Score = 35.4 bits (80), Expect = 0.091
 Identities = 56/290 (19%), Positives = 104/290 (35%), Gaps = 46/290 (15%)

Query: 63  TIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQ 122
           T ++ +   +  L +P  ++++   G  + S   QG   +     + S+          +
Sbjct: 499 TNSEGSSQPEEQLKSPMAESLD---GGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEK 555

Query: 123 IGNGPSHVSMQQTAP-NTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNI-- 179
            G+ P+  +  +    N  P      + PG      +S G P   + T+G  VSR  +  
Sbjct: 556 AGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTG 615

Query: 180 -----------NMQSNPVSMMQQQA-----ATSHYSSAQ---------GGSQHYQGQSSI 214
                      + + +P +  +  +      TSH S  Q          G+++    S+ 
Sbjct: 616 RVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNH 675

Query: 215 AMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEP---MGQQY 271
              G G  G S  G    +   PS+   S +Y          Y  S G+A P    G   
Sbjct: 676 NGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRY---------SYKDSFGSAVPRNVSGFPQ 726

Query: 272 YPDGH--GDY-AYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQ 318
           YP G   GD+  + +     + +    +E  Q Y+   + +YS+    +Q
Sbjct: 727 YPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQ 776


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 74/304 (24%), Positives = 116/304 (38%), Gaps = 34/304 (11%)

Query: 86   GPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSM 145
            G G   +S    G H     ++  S G   SS  Q +   G  H S  Q + +     S 
Sbjct: 3587 GHGHSAESSRQSGTHH----AENSSGGQAASSHEQARSSAGERHGSHHQQSAD-----SS 3637

Query: 146  SISGPGYSHAGPASQGVPMQG-QGTIGNYVSRTNINMQSNPVSMMQQQAAT-----SHYS 199
              SG G+   G AS  V   G +G+ G+  S +  + + +    +           SH  
Sbjct: 3638 RHSGIGH---GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQE 3694

Query: 200  SAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSH 259
            S +G S    G+S   +    +   S        P    +QGS  +         +    
Sbjct: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHE---------QARDS 3745

Query: 260  SQGAAEPMGQQYYPDGHGDY-AYQQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAG 316
            S+ +A   GQ       G     +Q SY EQS DRS    + H +    G S  S  Q+G
Sbjct: 3746 SRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSG 3805

Query: 317  YQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAP 376
             +  +A ++T +++Q      + G +    S Q   S++   Q GQG+  GS R+ +   
Sbjct: 3806 SR--SASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHS--QSGQGESAGSRRSRRQGS 3861

Query: 377  SAQQ 380
            S  Q
Sbjct: 3862 SVSQ 3865



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 73/304 (24%), Positives = 116/304 (38%), Gaps = 34/304 (11%)

Query: 88   GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSI 147
            G    S    G H     +++ S G   SS  Q +   G  H S  Q + +     S   
Sbjct: 1320 GHSADSSRQSGTHH----TESSSHGQAVSSHEQARSSPGERHGSRHQQSAD-----SSRH 1370

Query: 148  SGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAAT-----SHYSSAQ 202
            SG G+  A  A +    +G    G+ V+ +  + + +    +           SH  SA+
Sbjct: 1371 SGIGHRQASSAVRDSGHRGSS--GSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESAR 1428

Query: 203  GGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQG 262
            G S    G+S   +    S   S       AP    +QGS      ++     ++S SQ 
Sbjct: 1429 GQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRH----EQARNSSRHSASQD 1484

Query: 263  AAEPMGQQYYPDGH--GDYAYQQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGYQ 318
              + +       GH       +Q SY EQS DRS      H +    G S  S  Q+G +
Sbjct: 1485 GQDTI------RGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPR 1538

Query: 319  QGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSA 378
              +A +QT +++Q      + G +    S +   S++   Q GQG+  GS  + +   S 
Sbjct: 1539 --SASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHS--QVGQGESAGSKTSRRQGSSV 1594

Query: 379  QQQR 382
             Q R
Sbjct: 1595 SQDR 1598



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 73/286 (25%), Positives = 111/286 (38%), Gaps = 33/286 (11%)

Query: 106  SDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQ 165
            +++ S G   SS  Q +   G  H S  Q         S   SG G+   G AS  V   
Sbjct: 1982 TESSSRGQAASSHEQARSSAGERHGSHHQLQS----ADSSRHSGIGH---GQASSAVRDS 2034

Query: 166  G-QGTIGNYVSRTNINMQSNPVSMMQQQAAT-----SHYSSAQGGSQHYQGQSS--IAMM 217
            G +G  G+  S +  + + +    +  Q        SH  SA+G S    G+S   +  +
Sbjct: 2035 GHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQV 2094

Query: 218  GQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHG 277
                Q  S  GQ   AP    +QGS         +Y +    S+ +A   GQ       G
Sbjct: 2095 STHEQSESTHGQS--APSTGGRQGS---------HYDQAQDSSRHSASQEGQDTIRGHPG 2143

Query: 278  -DYAYQQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGYQQGAAQQQTYSQQQYPS 334
                 +Q S+ EQS DRS    + H +    G S  S+ Q+G +  +A ++TY ++Q   
Sbjct: 2144 PSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR--SASRKTYDKEQSGD 2201

Query: 335  QQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380
               + G      S+    S++     GQGQ  G   +     S  Q
Sbjct: 2202 GSRHSGSHHHEASSWADSSRHS--LVGQGQSSGPRTSRPRGSSVSQ 2245



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 19/201 (9%)

Query: 184  NPVSMMQQQAATSHY--SSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPS--- 238
            +P S  + +A   H   SS Q G++H Q  S         Q  S  G+R  + ++ S   
Sbjct: 2605 HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2664

Query: 239  ---------QQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQ 289
                     Q  S+ +  G   Y G Q S ++G +E    Q     HG     Q S+ E 
Sbjct: 2665 SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV-SAHGQAGSHQQSHQES 2723

Query: 290  SYDRSFE---ESTQHYYEGGNSQYSQQQAGYQQGAAQ-QQTYSQQQYPSQQSYPGQQQGY 345
            +  RS E    S    Y+    + S+   G+   + + +Q    +Q      +   Q G 
Sbjct: 2724 ARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQ 2783

Query: 346  GSAQGAPSQYPGYQQGQGQQY 366
             + +G P    G +QG   ++
Sbjct: 2784 DTIRGHPGSSRGGRQGYHHEH 2804



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 19/201 (9%)

Query: 184  NPVSMMQQQAATSHY--SSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPS--- 238
            +P S  + +A   H   SS Q G++H Q  S         Q  S  G+R  + ++ S   
Sbjct: 2929 HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2988

Query: 239  ---------QQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQ 289
                     Q  S+ +  G   Y G Q S ++G +E    Q     HG     Q S+ E 
Sbjct: 2989 SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV-SAHGQAGSHQQSHQES 3047

Query: 290  SYDRSFE---ESTQHYYEGGNSQYSQQQAGYQQGAAQ-QQTYSQQQYPSQQSYPGQQQGY 345
            +  RS E    S    Y+    + S+   G+   + + +Q    +Q      +   Q G 
Sbjct: 3048 ARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQ 3107

Query: 346  GSAQGAPSQYPGYQQGQGQQY 366
             + +G P    G +QG   ++
Sbjct: 3108 DTIRGHPGSSRGGRQGYHHEH 3128



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 69/322 (21%), Positives = 109/322 (33%), Gaps = 28/322 (8%)

Query: 91   TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGP 150
            T++    G  S+ S S          S    Q G G S  +  +T+ N   + S      
Sbjct: 3489 TRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQS--AGPRTSRNQGSSVSQDSDSQ 3546

Query: 151  GYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHY--SSAQGGSQHY 208
            G+S       G   +         SR       +P S  + +A   H   SS Q G+ H 
Sbjct: 3547 GHSEDSERWSGSASRNHRGSAQEQSRDG---SRHPTSHHEDRAGHGHSAESSRQSGTHHA 3603

Query: 209  QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYY------------GEQ 256
            +  S         Q  S  G+R  + ++ S   S    +G  +              G Q
Sbjct: 3604 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQ 3663

Query: 257  YSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQH---YYEGGNSQYSQQ 313
             S S+G +E    Q     HG     Q S+ E +  RS   S +     Y+    + S+ 
Sbjct: 3664 ASDSEGHSEDSDTQSV-SAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSES 3722

Query: 314  ---QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYR 370
               +AG   G  Q   + Q +  S+ S    Q+G  + +G P    G +QG   +    R
Sbjct: 3723 AHGRAGPSTGGRQGSRHEQARDSSRHS--ASQEGQDTIRGHPGSRRGGRQGSYHEQSVDR 3780

Query: 371  APQTAPSAQQQRPYGYEQGQYG 392
            +  +          G     +G
Sbjct: 3781 SGHSGSHHSHTTSQGRSDASHG 3802



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 68/292 (23%), Positives = 108/292 (36%), Gaps = 31/292 (10%)

Query: 95   SSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSH 154
            S  G    GS     S+    S     Q+G G S  S  +T+ N   + S      G+S 
Sbjct: 1874 SGDGSRHSGSRHHEASSRADSSR--HSQVGQGQS--SGPRTSRNQGSSVSQDSDSQGHSE 1929

Query: 155  AGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHY--SSAQGGSQHYQGQS 212
                  G   +    +G+   ++    + +P S  + +A   H   SS Q G++H +  S
Sbjct: 1930 DSERWSGSASRNH--LGSAWEQSRDGSR-HPGSHHEDRAGHGHSADSSRQSGTRHTESSS 1986

Query: 213  SIAMMGQGSQGSSMMGQRPMAPYR-------------PSQQGSSQQYLGQEEYYGEQYSH 259
                     Q  S  G+R  + ++               Q  S+ +  G   Y G Q S 
Sbjct: 1987 RGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD 2046

Query: 260  SQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ---HYYEGGNSQYSQQ--- 313
            S+G +E    Q      G     Q S+ E +  +S E S +     Y+    + S+    
Sbjct: 2047 SEGHSEDSDTQSV-SAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHG 2105

Query: 314  QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ 365
            Q+    G  Q   Y Q Q  S+ S    Q+G  + +G P    G +QG  Q+
Sbjct: 2106 QSAPSTGGRQGSHYDQAQDSSRHS--ASQEGQDTIRGHPGPSRGGRQGSHQE 2155



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 53/233 (22%), Positives = 86/233 (36%), Gaps = 31/233 (13%)

Query: 184 NPVSMMQQQAATSHY--SSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQG 241
           +P S  + +A+  H   SS Q G++H +  S         Q  S  G+R  + ++ S   
Sbjct: 335 HPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADS 394

Query: 242 SSQQYLGQEEYY------------GEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQ 289
           S     G+ +              G Q S S+G +E    Q    GHG    +Q S+ E 
Sbjct: 395 SRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSV-SGHGKAGLRQQSHQES 453

Query: 290 SYDRSFEESTQHYYEGGNSQY----------SQQQAGYQQGAAQQQTYSQQQYPSQQSYP 339
           +  RS E S +     G+S Y          +  + G   G  Q   + Q +  S+ S  
Sbjct: 454 TRGRSGERSGR----SGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHS-- 507

Query: 340 GQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYG 392
             Q+G  + +G P    G +QG   +    R+  +          G     +G
Sbjct: 508 ASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHG 560



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 69/319 (21%), Positives = 113/319 (35%), Gaps = 40/319 (12%)

Query: 93  SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTS-------- 144
           SGS+   H   +   +      P S  + +  +G S  S +Q+      T+S        
Sbjct: 314 SGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSH 373

Query: 145 -MSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQG 203
             + S PG  H     Q          G   + + ++ + +  S    QA+ S   S   
Sbjct: 374 EQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSS-GSQASDSEGHSENS 432

Query: 204 GSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYY---------- 253
            +Q   G     +  Q  Q S+    R  +  R  + GSS   +   E            
Sbjct: 433 DTQSVSGHGKAGLRQQSHQEST----RGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTS 488

Query: 254 --GEQYSHSQGAAEPMGQQYYPDGH--------GDYAYQQSSYTEQSYDRSFEESTQHYY 303
             G Q SH + A +        +G              +Q S+ EQS +RS    + H +
Sbjct: 489 TGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSH 548

Query: 304 --EGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQG 361
               G S  S  Q+G +  +A +QT +++Q      + G +    S+Q   S++   Q G
Sbjct: 549 TTSQGRSDASHGQSGSR--SASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHS--QVG 604

Query: 362 QGQQYGSYRAPQTAPSAQQ 380
           QGQ  G   +     S  Q
Sbjct: 605 QGQSSGPRTSRNQGSSVSQ 623



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 75/303 (24%), Positives = 119/303 (39%), Gaps = 31/303 (10%)

Query: 86  GPGALTQSGSSQGL-HSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTS 144
           G G    S    G  H+Q S     S+G   SS  Q +   G  H S  Q         S
Sbjct: 669 GHGHSADSSRKSGTRHTQNS-----SSGQAASSHEQARSSAGERHGSRHQLQS----ADS 719

Query: 145 MSISGPGYSHAGPASQGVPMQG-QGTIGNYVSRTNINMQ-SNPVSMMQQQAATSHYSSAQ 202
              SG G+   G AS  V   G +G+ G+  + +  + + S+  S+     A  H  S Q
Sbjct: 720 SRHSGTGH---GQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQ 776

Query: 203 GGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLG--QEEYYGEQYSHS 260
             ++   G+ S        +  S + Q        S  G +    G  Q  ++ +   +S
Sbjct: 777 ESARDRSGERS-------RRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNS 829

Query: 261 QGAAEPMGQQYYPDGHGDYAY-QQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGY 317
           + +A   GQ       G     +Q S+ EQS DRS    + H +    G S  S+ Q+G 
Sbjct: 830 RHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGS 889

Query: 318 QQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPS 377
           +  +A + T +++Q      + G +    S+    S++   Q GQGQ  GS  + +   S
Sbjct: 890 R--SASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHS--QAGQGQSEGSRTSRRQGSS 945

Query: 378 AQQ 380
             Q
Sbjct: 946 VSQ 948



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 46/212 (21%), Positives = 76/212 (35%), Gaps = 21/212 (9%)

Query: 199  SSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEE------- 251
            SS Q G+ H +  S    +    Q  S  G+R  + ++ S   S    +G  +       
Sbjct: 1325 SSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRD 1384

Query: 252  -----YYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFE---ESTQHYY 303
                   G Q ++S+G +E    Q     HG     Q S+ E +  +S E    S    Y
Sbjct: 1385 SGHRGSSGSQVTNSEGHSEDSDTQSV-SAHGQAGPHQQSHKESARGQSGESSGRSRSFLY 1443

Query: 304  EGGNSQYSQQ---QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360
            +  + + S+    Q     G  Q   + Q +  S+ S    Q G  + +G P    G +Q
Sbjct: 1444 QVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHS--ASQDGQDTIRGHPGSSRGGRQ 1501

Query: 361  GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYG 392
            G   +    R+  +        P G     +G
Sbjct: 1502 GSYHEQSVDRSGHSGYHHSHTTPQGRSDASHG 1533



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 47/210 (22%), Positives = 75/210 (35%), Gaps = 11/210 (5%)

Query: 191  QQAATSHYSSAQGG---SQHYQGQSSIAMM-GQGSQGSSMMGQRPMAPYRPSQQGSSQQY 246
            +Q+ T H  ++ GG   S H Q +SS     G   Q S+   +    P R  Q  S+ + 
Sbjct: 1003 RQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRR--QASSAVRD 1060

Query: 247  LGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYD----RSFEESTQHY 302
             G     G Q S S+G +E    Q    GHG     Q S+ E + D    RS    +  Y
Sbjct: 1061 SGHWGSSGSQASDSEGHSEESDTQSV-SGHGQDGPHQQSHQESARDWSGGRSGRSGSFIY 1119

Query: 303  YEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQ 362
                + Q        +    ++Q    +Q      +   Q+G  + +  P    G +QG 
Sbjct: 1120 QVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGS 1179

Query: 363  GQQYGSYRAPQTAPSAQQQRPYGYEQGQYG 392
              +    R+  +          G     +G
Sbjct: 1180 HHEQSVDRSGHSGSHHSHTTSQGRSDASHG 1209



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 67/297 (22%), Positives = 106/297 (35%), Gaps = 54/297 (18%)

Query: 89   ALTQSGSSQGLHSQGSLSDAISTGLP---PSSLLQGQIGNGPSHVSMQQTAPNTLPTTSM 145
            A +  G   G   Q S   +  +G+P    SS ++     G S      +  ++  + + 
Sbjct: 3294 ARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQ 3353

Query: 146  SISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGS 205
            S+SG G   AGP  Q      +   G    R+         S + Q +      SA G +
Sbjct: 3354 SVSGHG--QAGPHQQSHQESARDRSGGRSGRSG--------SFLYQVSTHEQSESAHGRT 3403

Query: 206  QHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265
            +   G+          QGS     R  + +  SQ+G       Q+   G   S  +G   
Sbjct: 3404 RTSTGRR---------QGSHHEQARDSSRHSASQEG-------QDTIRGHPGSSRRG--- 3444

Query: 266  PMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGYQQGAAQ 323
                            +Q S+ EQS DRS    + H +    G S  S+ Q+G +  +A 
Sbjct: 3445 ----------------RQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR--SAS 3486

Query: 324  QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380
            +QT + +Q      +        S Q   S++   Q GQGQ  G   +     S  Q
Sbjct: 3487 RQTRNDEQSGDGSRHSWSHHHEASTQADSSRHS--QSGQGQSAGPRTSRNQGSSVSQ 3541



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 48/198 (24%), Positives = 74/198 (37%), Gaps = 23/198 (11%)

Query: 184  NPVSMMQQQAATSHY--SSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPS--- 238
            +P S  + +A   H   SS Q G+ H +  S         Q  S  G+R  + ++ S   
Sbjct: 2281 HPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS 2340

Query: 239  ---------QQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQ 289
                     Q  S+ +  G     G Q S S+G +E    Q     HG     Q S+ E 
Sbjct: 2341 SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSV-SAHGQAGPHQQSHQES 2399

Query: 290  SYDRSFEESTQ---HYYEGGNSQYSQQ---QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQ 343
            +  RS   S +     Y+    + S+    + G   G  Q   + Q +  S+ S    Q+
Sbjct: 2400 TRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHS--TSQE 2457

Query: 344  GYGSAQGAPSQYPGYQQG 361
            G  +  G P    G +QG
Sbjct: 2458 GQDTIHGHPGSSSGGRQG 2475



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 68/317 (21%), Positives = 123/317 (38%), Gaps = 43/317 (13%)

Query: 91  TQSGSSQGLHSQGSLSDAIS----TGLPPSSLLQGQIG-----NGPSHVSMQQTAPNTLP 141
           +Q+  S+G HS+ S + ++S     GL   S  +   G     +G S  S+ Q + +  P
Sbjct: 420 SQASDSEG-HSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQP 478

Query: 142 T-----TSMSISGPGYSHAGPASQG----VPMQGQGTIGNYVSRTNINMQSN--PVSMMQ 190
                 T  S  G   SH   A          +GQ TI  +   +    Q +    S+ +
Sbjct: 479 DSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNR 538

Query: 191 QQAATSHYS--SAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ---- 244
              + SH+S  ++QG S    GQS      + ++     G           + SSQ    
Sbjct: 539 SGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSS 598

Query: 245 --QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHY 302
               +GQ +  G + S +QG++  + Q     GH + + + S    +++  S +E ++  
Sbjct: 599 RHSQVGQGQSSGPRTSRNQGSS--VSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSR-- 654

Query: 303 YEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQ 362
            +G     S  +     G +   +       +Q S  GQ         A S +   +   
Sbjct: 655 -DGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQ---------AASSHEQARSSA 704

Query: 363 GQQYGSYRAPQTAPSAQ 379
           G+++GS    Q+A S++
Sbjct: 705 GERHGSRHQLQSADSSR 721



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 64/284 (22%), Positives = 102/284 (35%), Gaps = 54/284 (19%)

Query: 89   ALTQSGSSQGLHSQGSLSDAISTGL---PPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSM 145
            A + +G   G H Q S   +  +G+     SS ++     G S      +  ++  + + 
Sbjct: 2322 ARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQ 2381

Query: 146  SISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGS 205
            S+S  G   AGP  Q      +G       R+         S + Q +      SA G +
Sbjct: 2382 SVSAHG--QAGPHQQSHQESTRGRSAGRSGRSG--------SFLYQVSTHEQSESAHGRT 2431

Query: 206  QHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265
                G         G QGS     R  + +  SQ+G       Q+  +G   S S G   
Sbjct: 2432 GTSTG---------GRQGSHHKQARDSSRHSTSQEG-------QDTIHGHPGSSSGG--- 2472

Query: 266  PMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGYQQGAAQ 323
                            +Q S+ EQ  DRS    + H +    G S  S   +G +  +A 
Sbjct: 2473 ----------------RQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSR--SAS 2514

Query: 324  QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYG 367
            +QT + +Q      + G +    S++   S +   Q GQGQ  G
Sbjct: 2515 RQTRNDEQSGDGSRHSGSRHHEASSRADSSGHS--QVGQGQSEG 2556



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 67/300 (22%), Positives = 109/300 (36%), Gaps = 40/300 (13%)

Query: 91   TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSM-SISG 149
            T  G S   H Q     A        +  + Q G+G  H   +   P+T   +S  S  G
Sbjct: 1523 TPQGRSDASHGQSGPRSASR-----QTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVG 1577

Query: 150  PGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQH-- 207
             G S     S+    QG     +  S  +    S       + A+ +HY SA+  S+H  
Sbjct: 1578 QGESAGSKTSR---RQGSSVSQDRDSEGH----SEDSERRSESASRNHYGSAREQSRHGS 1630

Query: 208  ---YQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQE--EYYGEQYSHSQG 262
                  Q   A  G  ++ S   G R        Q  SSQ+       E +G ++  S  
Sbjct: 1631 RNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSAD 1690

Query: 263  AAEPMGQQYYPD-------GHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQ-- 313
            ++   G     D       G+   +  Q+S +E   + S  +S   + + G  Q S Q  
Sbjct: 1691 SSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQES 1750

Query: 314  ---QAGYQQGAA-----QQQTYSQQQYPSQQSYP---GQQQGYGSAQGAPSQYPGYQQGQ 362
               Q+G + G +     Q  T+ Q +    ++ P   G+Q+         S++   Q+GQ
Sbjct: 1751 TRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQ 1810



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 60/239 (25%), Positives = 94/239 (39%), Gaps = 19/239 (7%)

Query: 166  GQGTIGNYVSRTNINMQSNPVSMMQ--QQAATSHYSSAQGGSQHYQGQSSIAMMG-QGSQ 222
            G  T G   SR      S+  S  Q  Q     H  S++GG Q Y  + S+   G  GS 
Sbjct: 2756 GPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSH 2815

Query: 223  GSSMMGQ-RPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAY 281
             S    Q R  A    S   S+ +    EE  G+   HS G+       +        A 
Sbjct: 2816 HSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHS-GSRHHEASTHADISRHSQAV 2874

Query: 282  QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAG----YQQGAAQQQTYSQQQYPSQQS 337
            Q  S   +   R     +Q     G+S+ S++ +G       G+AQ+Q     ++P  +S
Sbjct: 2875 QGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHP--RS 2932

Query: 338  YPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
            +   + G+G +  + S+  G +  Q    G     Q A S +Q R    E  ++G++ Q
Sbjct: 2933 HQEDRAGHGHSADS-SRQSGTRHTQTSSGG-----QAASSHEQARSSAGE--RHGSHHQ 2983



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 80/397 (20%), Positives = 136/397 (34%), Gaps = 89/397 (22%)

Query: 89   ALTQSGSSQGLHSQGSLSDAISTGL---PPSSLLQ--GQIGNGPSHVSMQQTAPNTLPTT 143
            A + +G   G H Q S   +  +G+     SS ++  G  G   S  S  +       T 
Sbjct: 2970 ARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQ 3029

Query: 144  SMSISGPGYSHAGP---ASQGVPMQGQGTIGNYVSRTNINMQS----------------- 183
            S+S  G   SH      +++G   +  G  G+++ + + + QS                 
Sbjct: 3030 SVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGS 3089

Query: 184  ----------NPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMG-QGSQGSSMMGQ-RP 231
                      +  S   Q     H  S++GG Q Y  + S+   G  GS  S    Q R 
Sbjct: 3090 RHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRS 3149

Query: 232  MAPYRPSQQGSSQQYLGQEEYYGEQYSHS--------------------QGAAE------ 265
             A    S   S+ +    EE  G+   HS                    QG +E      
Sbjct: 3150 DASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSR 3209

Query: 266  ----PMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQH-------YYEG----GNSQY 310
                 + Q    +GH + + + S    +++  S +E ++H       ++E     G+S  
Sbjct: 3210 RQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSAD 3269

Query: 311  SQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGA-PSQYPGYQQGQGQ----- 364
              +Q+G +         +   +   +S PG++ G    Q A  S++ G  +GQ       
Sbjct: 3270 RSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRD 3329

Query: 365  -----QYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
                   GS  +     S +         GQ G +QQ
Sbjct: 3330 SRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQ 3366



 Score = 37.0 bits (84), Expect = 0.031
 Identities = 59/287 (20%), Positives = 100/287 (34%), Gaps = 53/287 (18%)

Query: 148  SGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPV----SMMQQQAATSHYS---- 199
            +G G+S       G P   + + G   + ++   +S+P     S  QQ A +S +S    
Sbjct: 993  AGHGHSADSSRQSGTP-HAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPR 1051

Query: 200  ----SAQGGSQHYQGQSSIAMMGQG----SQGSSMMGQRPMAPYRPSQQGSSQQYLG--- 248
                SA   S H+    S A   +G    S   S+ G     P++ S Q S++ + G   
Sbjct: 1052 RQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRS 1111

Query: 249  ---------------QEEYYGE--------QYSHSQGAAEPMGQQYYPDGHGDYAY---- 281
                            E  +G         Q SH + A +        +G          
Sbjct: 1112 GRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGS 1171

Query: 282  ----QQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQ 335
                +Q S+ EQS DRS    + H +    G S  S  Q+G +  + Q +   Q    S+
Sbjct: 1172 RRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSR 1231

Query: 336  QSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQR 382
             S     +    A  +     G +Q  G +   ++    +  +  +R
Sbjct: 1232 HSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSER 1278



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 51/214 (23%), Positives = 80/214 (37%), Gaps = 34/214 (15%)

Query: 196  SHYS--SAQGGSQHYQGQSSIAMMG-------QGSQGSSMMGQRPMAPYRPSQQGSSQQY 246
            SH+S  ++QG S    GQS             Q   GS   G R    +  S Q  S ++
Sbjct: 3786 SHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSR---HHEASTQADSSRH 3842

Query: 247  --LGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYE 304
               GQ E  G + S  QG++                    +Y E S  RS   S  H+  
Sbjct: 3843 SQSGQGESAGSRRSRRQGSSVSQDS------------DSEAYPEDSERRSESASRNHH-- 3888

Query: 305  GGNSQYSQQQAGYQQGAAQQQTYSQ-QQYPSQ-QSYPGQQQGYGSAQGAPSQYPGYQQGQ 362
             G+S+   +      G++ + T S  Q  P Q  S   ++ G+ S+    S Y    Q +
Sbjct: 3889 -GSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSR 3947

Query: 363  GQQYGSYRAPQTAPSAQQQRPYG---YEQGQYGN 393
            G  + S      +   ++Q+      +  G YG+
Sbjct: 3948 GSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGS 3981



 Score = 36.2 bits (82), Expect = 0.053
 Identities = 55/264 (20%), Positives = 99/264 (37%), Gaps = 34/264 (12%)

Query: 165  QGQGTIGNYVSRTNINMQSNPVSMMQQQA--ATSHYS--SAQGGSQHYQGQSSIAMMGQG 220
            +GQ TI  +   +    Q +       ++  + SH+S  ++QG S   +GQS      + 
Sbjct: 3429 EGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQ 3488

Query: 221  SQGSSMMGQRPMAPYRPSQQGSSQ------QYLGQEEYYGEQYSHSQGAAEPMGQQYYPD 274
            ++     G      +    + S+Q         GQ +  G + S +QG++  + Q     
Sbjct: 3489 TRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSS--VSQDSDSQ 3546

Query: 275  GHGDYAYQQS---------SYTEQSYDRSFEESTQHYYEG--GNSQYSQQQAGYQQGAAQ 323
            GH + + + S         S  EQS D S   ++ H      G+S  S +Q+G       
Sbjct: 3547 GHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENS 3606

Query: 324  QQTYSQQQYPSQQSYPGQQQGYGSAQGA-PSQYPGYQQGQGQQYGSYRAPQTAPSAQQQR 382
                +   +   +S  G++ G    Q A  S++ G   GQ          + +  +Q   
Sbjct: 3607 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASD 3666

Query: 383  PYGYEQ----------GQYGNYQQ 396
              G+ +          GQ G +QQ
Sbjct: 3667 SEGHSEDSDTQSVSAHGQAGPHQQ 3690



 Score = 35.8 bits (81), Expect = 0.069
 Identities = 62/301 (20%), Positives = 100/301 (33%), Gaps = 31/301 (10%)

Query: 87  PGALTQSGSSQGLHSQGSLSDAISTGLPPSSLL-QGQIGNGPSHVSMQQTAPNTLPTTSM 145
           PG    SG  Q   S  S   A   G   S++  +G  G+  S  S  +       T S+
Sbjct: 380 PGERHGSGHQQSADS--SRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSV 437

Query: 146 SISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQ----QAATSHYSSA 201
           S    G+  AG   Q      +G  G    R+  ++    VS  +Q       T   +  
Sbjct: 438 S----GHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQ--VSTHEQPDSAHGRTGTSTGG 491

Query: 202 QGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQ 261
           + GS H Q + S          +S  GQ  +  +  S +G            G Q SH +
Sbjct: 492 RQGSHHEQARDS------SRHSASQEGQDTIRGHPGSSRG------------GRQGSHHE 533

Query: 262 GAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGA 321
            +    G       H     +  +   QS  RS    T++  + G+         ++  +
Sbjct: 534 QSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASS 593

Query: 322 AQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQ 381
               +   Q    Q S P   +  GS+    S   G+ +   +  GS        + +Q 
Sbjct: 594 QADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQS 653

Query: 382 R 382
           R
Sbjct: 654 R 654



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 61/292 (20%), Positives = 101/292 (34%), Gaps = 30/292 (10%)

Query: 115  PSSLLQGQIGNGPSHVSMQQTAPNTLPTTS---------MSISGPGYSHAGPASQGVPMQ 165
            P S  + +  +G S  S +Q+      T+S          + S PG  H     Q     
Sbjct: 1633 PRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSS 1692

Query: 166  GQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYS--------SAQGGSQHYQGQSSIAMM 217
                 G     + +    N  S   Q + +  +S        SA G +  +Q     +  
Sbjct: 1693 TDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTR 1752

Query: 218  GQGSQGSSMMGQRPMAPYRPSQQGSSQQYLG------QEEYYGEQYSHSQGAAEPMGQQY 271
            GQ  + S   G          Q  S+    G      Q   + +    S+ +A   GQ  
Sbjct: 1753 GQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDT 1812

Query: 272  YPDGHGDY-AYQQSSYTEQSYDRSFEESTQHYYEGG--NSQYSQQQAGYQQGAAQQQTYS 328
                 G     +Q S+ EQS D S    + H +      S  S+ Q+G +  +  +QT +
Sbjct: 1813 IRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSR--SVSRQTRN 1870

Query: 329  QQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380
            ++Q      + G +    S++   S++   Q GQGQ  G   +     S  Q
Sbjct: 1871 EKQSGDGSRHSGSRHHEASSRADSSRHS--QVGQGQSSGPRTSRNQGSSVSQ 1920



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 43/180 (23%), Positives = 72/180 (40%), Gaps = 27/180 (15%)

Query: 196  SHYS--SAQGGSQHYQGQSSIAMMG-------QGSQGSSMMGQR--PMAPYRPSQQGSSQ 244
            SH+S  ++QG S    GQS             Q   GS   G R    A +  S + S  
Sbjct: 1193 SHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQ- 1251

Query: 245  QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ---- 300
              +GQE+  G + S  QG++  + Q    + H D + + S    +++  S  E ++    
Sbjct: 1252 --VGQEQSSGSRTSRHQGSS--VSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSR 1307

Query: 301  ----HYYEG---GNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPS 353
                H  +    G+S  S +Q+G     +     +   +   +S PG++ G    Q A S
Sbjct: 1308 HPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADS 1367



 Score = 30.8 bits (68), Expect = 2.2
 Identities = 58/308 (18%), Positives = 105/308 (34%), Gaps = 20/308 (6%)

Query: 62   ATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQG 121
            + + DS     S   A  ++  +      + SG  Q  H Q S  ++        S   G
Sbjct: 732  SAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSG 791

Query: 122  Q-IGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180
              +    +H   + +   T P+T +            +       GQ TI  +   +   
Sbjct: 792  SFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRG 851

Query: 181  MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240
             Q    S  +Q    S +S +       QG+S  +    GS+ +S    R       S+ 
Sbjct: 852  RQG---SHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS----RTTRNEEQSRD 904

Query: 241  GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300
            GS  ++ G   +  E  SH+  +      Q   +G      Q SS ++ S      E ++
Sbjct: 905  GS--RHSGSRHH--EASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSE 960

Query: 301  HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360
                    ++S   +   +G+AQ+Q+    ++P          G+ +     S  P  + 
Sbjct: 961  --------RWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAET 1012

Query: 361  GQGQQYGS 368
              G Q  S
Sbjct: 1013 SSGGQAAS 1020


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 59/187 (31%), Positives = 69/187 (36%), Gaps = 14/187 (7%)

Query: 204 GSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYS---HS 260
           G Q +  QSS      G  G S +    M    PS QG     L Q++      S   + 
Sbjct: 486 GQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNP 545

Query: 261 QGAAEPMGQQYYPDGH--GDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQ 318
             A EP      P  H   D A QQ      S ++    S  HY +    Q  QQQ   Q
Sbjct: 546 HPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKP---SLLHYTQQQQQQQQQQQQQQQ 602

Query: 319 QGAAQQQTYSQQQYPSQQ------SYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP 372
           Q   QQQ   QQQ   QQ          QQQ   SAQ    Q    QQ Q QQ    +  
Sbjct: 603 QQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQ 662

Query: 373 QTAPSAQ 379
           Q  PS+Q
Sbjct: 663 QQQPSSQ 669



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 79/307 (25%), Positives = 102/307 (33%), Gaps = 52/307 (16%)

Query: 126 GPSHVSMQQTAPNTLPTTSMSISGPGYSH---AGPASQGVPMQGQGTIGNYVSRTNIN-- 180
           GPS  S Q   P+  P  SM+ S    S    + P SQ  P  G G      S   ++  
Sbjct: 375 GPSG-SPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHA 433

Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQG-----SSMMGQRPMAPY 235
            Q   ++  +QQ A       Q    ++    S A    G  G     S   GQ+  +P 
Sbjct: 434 QQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQ 493

Query: 236 R---PSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYD 292
               P   G S Q      Y  +    +QG            GH D   QQ     Q   
Sbjct: 494 SSPMPGVAGGSGQSKVMANYMYKAGPSAQG------------GHLDVLMQQKP---QDLS 538

Query: 293 RSF-----------EESTQHYYEGGNSQYSQQQAG------------YQQGAAQQQTYSQ 329
           RSF           + +T+  +   + Q +QQ               Y Q   QQQ   Q
Sbjct: 539 RSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQ 598

Query: 330 QQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQG 389
           QQ   QQ    QQQ     Q   S     QQ Q Q   S +  Q     QQQ+    +Q 
Sbjct: 599 QQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQ 658

Query: 390 QYGNYQQ 396
           Q    QQ
Sbjct: 659 QQQQQQQ 665



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 77/348 (22%), Positives = 109/348 (31%), Gaps = 52/348 (14%)

Query: 67  SNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNG 126
           +N  + +  P P        P   T SG+S+ L S   +S A          L+    N 
Sbjct: 394 ANSALSTSSPIPSVPQSQAQPQ--TGSGASRALPSWQEVSHA--------QQLKQIAANR 443

Query: 127 PSHVSMQQ----------------TAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQG-- 168
             H  MQQ                  P+  P     I  P +     + Q  PM G    
Sbjct: 444 QQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGG 503

Query: 169 -----TIGNYVSRTNINMQSNPVSMMQQQA----ATSHYSSAQGGSQHYQGQSSIAMMGQ 219
                 + NY+ +   + Q   + ++ QQ     + S  ++     +  QG +       
Sbjct: 504 SGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFN 563

Query: 220 GSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDY 279
             Q +  M         PSQ   S  +  Q++   +Q    Q   +   QQ         
Sbjct: 564 SDQANQQMPS-----VLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 618

Query: 280 AYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYP 339
             Q S   +Q   +    S Q   +    Q  QQQ   QQ   QQQ  S Q   S  S P
Sbjct: 619 QQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQP 678

Query: 340 --------GQQQGYGSAQGAPSQYPGYQ--QGQGQQYGSYRAPQTAPS 377
                    Q+      Q  P    GYQ  Q Q Q   S     T PS
Sbjct: 679 LLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPS 726


>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
           sapiens]
          Length = 354

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 75/271 (27%), Positives = 97/271 (35%), Gaps = 43/271 (15%)

Query: 128 SHVSMQQTAP--NTLPTTSMSISGPGYSH-AGPASQGVPMQGQGTIGNYVSRTNINMQSN 184
           S+   Q TA    T   TS      GY+    P +   P+QG GT G Y + T     + 
Sbjct: 51  SYTQAQTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGT-GAYDTTT-----AT 104

Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244
             +     AA S Y +              A    G Q ++    RP    +P++    Q
Sbjct: 105 VTTTQASYAAQSAYGTQP------------AYPAYGQQPAATAPTRPQDGNKPTETSQPQ 152

Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYE 304
              G        Y  S  +        YP   G Y  Q  +        S+  +    Y+
Sbjct: 153 SSTGGYNQPSLGYGQSNYS--------YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYD 204

Query: 305 GGNSQYSQQQA-GYQQGAAQQQTYSQQQYPSQQ---SYPGQQQGYGSAQGAPSQYPGYQQ 360
              S YSQQ   G      QQ +Y QQ    QQ   SYP Q    GS   APSQY     
Sbjct: 205 --QSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQT---GSYSQAPSQYSQQSS 259

Query: 361 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391
             GQQ  S+R  Q  PS+     YG E G +
Sbjct: 260 SYGQQ-SSFR--QDHPSS--MGVYGQESGGF 285



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 51/220 (23%), Positives = 73/220 (33%), Gaps = 21/220 (9%)

Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240
           M S   S   Q AA   YS+    +Q  QG +       G Q     GQ     Y  +Q 
Sbjct: 1   MASTDYSTYSQAAAQQGYSAYT--AQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQT 57

Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300
            ++         YG+  +       P        G+G  AY  ++ T  +   S+   + 
Sbjct: 58  TATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSA 117

Query: 301 HYYEGGNSQYSQQQAGYQQGAAQ---QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357
           +  +     Y QQ A       Q   + T + Q   S   Y     GYG +  +  Q PG
Sbjct: 118 YGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG 177

Query: 358 YQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391
               Q         P TAP      S    +P  Y+Q  Y
Sbjct: 178 SYPMQ---------PVTAPPSYPPTSYSSTQPTSYDQSSY 208


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
           sapiens]
          Length = 655

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 75/271 (27%), Positives = 97/271 (35%), Gaps = 43/271 (15%)

Query: 128 SHVSMQQTAP--NTLPTTSMSISGPGYSH-AGPASQGVPMQGQGTIGNYVSRTNINMQSN 184
           S+   Q TA    T   TS      GY+    P +   P+QG GT G Y + T     + 
Sbjct: 51  SYTQAQTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGT-GAYDTTT-----AT 104

Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244
             +     AA S Y +              A    G Q ++    RP    +P++    Q
Sbjct: 105 VTTTQASYAAQSAYGTQP------------AYPAYGQQPAATAPTRPQDGNKPTETSQPQ 152

Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYE 304
              G        Y  S  +        YP   G Y  Q  +        S+  +    Y+
Sbjct: 153 SSTGGYNQPSLGYGQSNYS--------YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYD 204

Query: 305 GGNSQYSQQQA-GYQQGAAQQQTYSQQQYPSQQ---SYPGQQQGYGSAQGAPSQYPGYQQ 360
              S YSQQ   G      QQ +Y QQ    QQ   SYP Q    GS   APSQY     
Sbjct: 205 --QSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQT---GSYSQAPSQYSQQSS 259

Query: 361 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391
             GQQ  S+R  Q  PS+     YG E G +
Sbjct: 260 SYGQQ-SSFR--QDHPSS--MGVYGQESGGF 285



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 51/220 (23%), Positives = 73/220 (33%), Gaps = 21/220 (9%)

Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240
           M S   S   Q AA   YS+    +Q  QG +       G Q     GQ     Y  +Q 
Sbjct: 1   MASTDYSTYSQAAAQQGYSAYT--AQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQT 57

Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300
            ++         YG+  +       P        G+G  AY  ++ T  +   S+   + 
Sbjct: 58  TATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSA 117

Query: 301 HYYEGGNSQYSQQQAGYQQGAAQ---QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357
           +  +     Y QQ A       Q   + T + Q   S   Y     GYG +  +  Q PG
Sbjct: 118 YGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG 177

Query: 358 YQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391
               Q         P TAP      S    +P  Y+Q  Y
Sbjct: 178 SYPMQ---------PVTAPPSYPPTSYSSTQPTSYDQSSY 208


>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
           sapiens]
          Length = 656

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 75/271 (27%), Positives = 97/271 (35%), Gaps = 43/271 (15%)

Query: 128 SHVSMQQTAP--NTLPTTSMSISGPGYSH-AGPASQGVPMQGQGTIGNYVSRTNINMQSN 184
           S+   Q TA    T   TS      GY+    P +   P+QG GT G Y + T     + 
Sbjct: 51  SYTQAQTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGT-GAYDTTT-----AT 104

Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244
             +     AA S Y +              A    G Q ++    RP    +P++    Q
Sbjct: 105 VTTTQASYAAQSAYGTQP------------AYPAYGQQPAATAPTRPQDGNKPTETSQPQ 152

Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYE 304
              G        Y  S  +        YP   G Y  Q  +        S+  +    Y+
Sbjct: 153 SSTGGYNQPSLGYGQSNYS--------YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYD 204

Query: 305 GGNSQYSQQQA-GYQQGAAQQQTYSQQQYPSQQ---SYPGQQQGYGSAQGAPSQYPGYQQ 360
              S YSQQ   G      QQ +Y QQ    QQ   SYP Q    GS   APSQY     
Sbjct: 205 --QSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQT---GSYSQAPSQYSQQSS 259

Query: 361 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391
             GQQ  S+R  Q  PS+     YG E G +
Sbjct: 260 SYGQQ-SSFR--QDHPSS--MGVYGQESGGF 285



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 51/220 (23%), Positives = 73/220 (33%), Gaps = 21/220 (9%)

Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240
           M S   S   Q AA   YS+    +Q  QG +       G Q     GQ     Y  +Q 
Sbjct: 1   MASTDYSTYSQAAAQQGYSAYT--AQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQT 57

Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300
            ++         YG+  +       P        G+G  AY  ++ T  +   S+   + 
Sbjct: 58  TATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSA 117

Query: 301 HYYEGGNSQYSQQQAGYQQGAAQ---QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357
           +  +     Y QQ A       Q   + T + Q   S   Y     GYG +  +  Q PG
Sbjct: 118 YGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG 177

Query: 358 YQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391
               Q         P TAP      S    +P  Y+Q  Y
Sbjct: 178 SYPMQ---------PVTAPPSYPPTSYSSTQPTSYDQSSY 208


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 92/418 (22%), Positives = 132/418 (31%), Gaps = 57/418 (13%)

Query: 18   QQTIQKMLDE----NHHLIQCILEYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQS 73
            Q  IQK LD+           + EY++K +  +  Q QQ    + V LA     +  + +
Sbjct: 3571 QSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAV-LALSPSQSPRLLT 3629

Query: 74   LLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQ 133
             LP        L P      G + GL              P    L GQ G    + ++ 
Sbjct: 3630 KLPGQLLPGHGLQPPQGPPGGQAGGLRLT-----------PGGMALPGQPGGPFLNTALA 3678

Query: 134  QTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQA 193
            Q         + S++GP     G     + ++  G     +    + +Q   + + Q+  
Sbjct: 3679 QQQQQQHSGGAGSLAGPS---GGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQ 3735

Query: 194  ATSHYSSAQGGSQHYQGQSSIAMM---GQGSQGSSMMGQRPMAPYRPSQ-QGSSQQYLGQ 249
                    Q   QH  GQ +I      G G Q +  +G +P     PS  QG   Q L  
Sbjct: 3736 QQQQQQQQQ---QHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSP 3792

Query: 250  EEYYGEQ-----------YSHSQGAAEPMGQ---------------QYYPDGHGDYAY-- 281
            +   G Q                GA  P G                Q    G G   +  
Sbjct: 3793 QPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRL 3852

Query: 282  ---QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSY 338
               QQ    +Q   +       H  +   S   Q +   Q   + QQ   QQQ   QQ  
Sbjct: 3853 VTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQL 3912

Query: 339  PGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
              QQQ     Q    Q    QQ Q QQ    +  Q     QQ +    +Q Q    QQ
Sbjct: 3913 QQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQ 3970



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 68/250 (27%), Positives = 84/250 (33%), Gaps = 34/250 (13%)

Query: 149  GPGYSH---AGPASQGV--PMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQG 203
            GPG       GP  QG+  P   QG +   +S          +   Q       +  A G
Sbjct: 3760 GPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALG 3819

Query: 204  GS----QHYQGQSSIAMMGQ-GSQGSSMMGQRPMAPYRPSQQGSSQQY---LGQEEYYGE 255
                  Q    QS +    Q   QG  +MG R +   +  QQ   QQ     G       
Sbjct: 3820 PQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQS 3879

Query: 256  QYSHS---QGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQ 312
              SHS   + +A+PMG             QQ    +Q          Q   +    Q  Q
Sbjct: 3880 LMSHSGQPKLSAQPMGSLQQ--------LQQQQQLQQ----------QQQLQQQQQQQLQ 3921

Query: 313  QQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP 372
            QQ   QQ   QQQ   QQ    QQ    QQQ     Q    Q    QQ Q QQ G     
Sbjct: 3922 QQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981

Query: 373  QTAPSAQQQR 382
            +T  S QQQ+
Sbjct: 3982 RTLLSPQQQQ 3991



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 80/330 (24%), Positives = 106/330 (32%), Gaps = 51/330 (15%)

Query: 36   LEYQSKGKTAECTQYQQI-LHRNLVYLATIADSNQNMQS-----LLPAPPTQNMNLGPGA 89
            L  +S G  +   Q +Q+ L +  + LA      Q  Q      L      Q    GPG 
Sbjct: 3704 LALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGV 3763

Query: 90   LTQSG---SSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVS-MQQTAPNTLPTTSM 145
             T        QGL    S    +   L P      Q   GP+ V+ +QQ  P  L     
Sbjct: 3764 QTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGAL----- 3818

Query: 146  SISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSH-YSSAQGG 204
               GP     GP  Q             V  T   + S+P    Q Q    H   +AQ  
Sbjct: 3819 ---GP----QGPHRQ-------------VLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQ 3858

Query: 205  SQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAA 264
             Q  Q Q   +M G      S+M             GS QQ   Q++   +Q    Q   
Sbjct: 3859 QQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQ 3918

Query: 265  EPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQ 324
            +   QQ           QQ    +Q   +  ++  Q   +       QQQ   QQ   QQ
Sbjct: 3919 QLQQQQQL---------QQQQLQQQQQQQQLQQQQQQQLQ------QQQQQLQQQQQQQQ 3963

Query: 325  QTYSQQQYPSQQSYPGQQQGYGSAQGAPSQ 354
            Q + QQQ   Q     Q +   S Q    Q
Sbjct: 3964 QQFQQQQQQQQMGLLNQSRTLLSPQQQQQQ 3993



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 91/376 (24%), Positives = 132/376 (35%), Gaps = 42/376 (11%)

Query: 18   QQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSL--- 74
            QQ +Q+   +     Q  L+ Q + +  +  Q QQ     L+  +    S Q  Q     
Sbjct: 3937 QQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVA 3996

Query: 75   ----LPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLP--PSSLLQGQIGNGPS 128
                +PA P Q+ +  PGAL  +    G   Q ++  A+S+     PS+   G +  G +
Sbjct: 3997 LGPGMPAKPLQHFS-SPGALGPTLLLTG-KEQNTVDPAVSSEATEGPSTHQGGPLAIGTT 4054

Query: 129  HVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSM 188
              SM  T P  +  +    S        P  Q   +Q Q  +           Q   VS+
Sbjct: 4055 PESMA-TEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPL------RLPGQQQQQVSL 4107

Query: 189  MQQQAATSHYSSAQGGSQ------HYQGQSSIAMMGQ-GSQGSSMMG-QRPMAPYRPSQQ 240
            +      SH     G S       H   Q S+++  Q GS   +++G Q+PM   RP Q 
Sbjct: 4108 LHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLE-RPMQN 4166

Query: 241  GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300
             +  Q        G      QG     G    P      A  Q    +    R      Q
Sbjct: 4167 NTGPQ----PPKPGPVLQSGQGLP---GVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219

Query: 301  HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360
                    Q    Q   QQ  A +QT   Q+ P  Q+ P   QG    Q     +PG Q 
Sbjct: 4220 QQL-----QALLMQRQLQQSQAVRQTPPYQE-PGTQTSP--LQGLLGCQPQLGGFPGPQT 4271

Query: 361  GQGQQYGSYRAPQTAP 376
            G  Q+ G+   PQ  P
Sbjct: 4272 GPLQELGAGPRPQGPP 4287



 Score = 29.3 bits (64), Expect = 6.5
 Identities = 75/341 (21%), Positives = 117/341 (34%), Gaps = 59/341 (17%)

Query: 92   QSGSSQGLHSQGSLSDAISTG----LPPSSLLQGQIGNGPSHVSMQQTAPNTL-PTTSMS 146
            Q G   GL  Q S    +S      +PPS  ++      P  ++MQQ   N+  P T + 
Sbjct: 3360 QHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMK------PQQLAMQQQLANSFFPDTDLD 3413

Query: 147  ------ISGPGYSHAGPASQGVP-MQGQGTIGNYVSRTNINMQSNPVSMMQQQAA----- 194
                  I  P       A +G+  +  QG+IG         M    VS++ Q+ +     
Sbjct: 3414 KFAAEDIIDPIAKAKMVALKGIKKVMAQGSIG-----VAPGMNRQQVSLLAQRLSGGPSS 3468

Query: 195  -TSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRP----SQQGSSQQYLGQ 249
               ++ +A  G +   G  S       +    ++ +     Y      +QQ    Q    
Sbjct: 3469 DLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVL 3528

Query: 250  EEYYG------EQYSHSQGAAEPMGQQYYPDGHGD---YAYQQSSYTEQSYDRSFEESTQ 300
            EE  G      +     Q  A+  G+++ P+   +      +Q S  ++  D+  ++  +
Sbjct: 3529 EEQIGVHRKSRKALCAKQRTAKKAGREF-PEADAEKLKLVTEQQSKIQKQLDQVRKQQKE 3587

Query: 301  HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQS------YPGQ---QQGYGSAQGA 351
            H       +  QQQ   QQ   QQQ  +       QS       PGQ     G    QG 
Sbjct: 3588 HTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGP 3647

Query: 352  PSQY-------PGYQQGQGQQYGSYRAPQTAPSAQQQRPYG 385
            P          PG     GQ  G +     A   QQQ   G
Sbjct: 3648 PGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGG 3688


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 90/348 (25%), Positives = 120/348 (34%), Gaps = 49/348 (14%)

Query: 78   PPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQ--- 134
            PP    +  PG++T     QG     + +  +  G P     +      P  + MQ+   
Sbjct: 1817 PPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYR------PVRLPMQKLPT 1870

Query: 135  --TAPNTLPTTSMSISG--------PGYSHAGPA-SQGVPM-----QGQGTIGNYVSRTN 178
              T P  LPTT   + G          Y    PA  QG  +     Q QG +G   S  +
Sbjct: 1871 RPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQ--SSVH 1928

Query: 179  INMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQG--SSMMGQRP--MAP 234
                S+   +   Q  T  Y S  G  QH     ++      SQ   S+     P  + P
Sbjct: 1929 QMTPSSSYGLQTSQGYTP-YVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDP 1987

Query: 235  YRPSQQGSSQQYLGQEEYYG------EQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTE 288
             R  QQ  S     Q   YG      +++SH      PM     P          S+   
Sbjct: 1988 TRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTP---------MSAQGV 2038

Query: 289  QSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSA 348
            Q+  RS     +   +    Q  QQQ   QQ   QQQ Y  +Q   QQ    QQQ     
Sbjct: 2039 QAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQ 2098

Query: 349  QGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
            Q    Q    QQ Q QQ+   +  Q AP   Q +P    Q Q    QQ
Sbjct: 2099 QQQQQQQQQQQQQQQQQHQQQQQQQAAP--PQPQPQSQPQFQRQGLQQ 2144



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 77/274 (28%), Positives = 99/274 (36%), Gaps = 51/274 (18%)

Query: 101  SQGSLSDAISTGLPPSSL--LQGQIGNGP--SHVSMQQTAPNTLPTTSMSISGPGYSHAG 156
            SQG L  +    + PSS   LQ   G  P  SHV +QQ             +GP  +   
Sbjct: 1918 SQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQH------------TGPAGTMVP 1965

Query: 157  PASQGVPMQGQ--GTIGNYVSRTNINMQSNPVSMMQQQAATSHY---SSAQGGSQHYQGQ 211
            P+    P Q     T    V  T  ++Q  P   + QQA T  +   S+ +   Q  Q  
Sbjct: 1966 PSYSSQPYQSTHPSTNPTLVDPTR-HLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQT 2024

Query: 212  SSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQY 271
              I+ M   S      G R  A     QQ   QQ   Q++   +Q    Q       QQY
Sbjct: 2025 PMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQ-------QQY 2077

Query: 272  YPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQ 331
                H     QQ    +Q   +  ++  Q        Q  QQQ        QQQ + QQQ
Sbjct: 2078 ----HIRQQQQQQILRQQQQQQQQQQQQQQ-----QQQQQQQQ--------QQQQHQQQQ 2120

Query: 332  YPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ 365
               QQ+ P Q Q     Q    Q  G QQ Q QQ
Sbjct: 2121 --QQQAAPPQPQPQSQPQ---FQRQGLQQTQQQQ 2149


>gi|57165375 glutamate receptor, ionotropic, N-methyl
           D-aspartate-associated protein 1 [Homo sapiens]
          Length = 371

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 40/135 (29%), Positives = 46/135 (34%), Gaps = 26/135 (19%)

Query: 229 QRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDY---AYQQSS 285
           Q PM PY             Q  Y G  Y        P GQ  YP G   Y    Y Q  
Sbjct: 26  QPPMPPY------------AQPPYPGAPYPQPPFQPSPYGQPGYPHGPSPYPQGGYPQGP 73

Query: 286 YTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQ---- 341
           Y +  Y +        Y + G  Q    Q GY QG   Q  +    Y   Q +PGQ    
Sbjct: 74  YPQGGYPQG------PYPQEGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDPDS 127

Query: 342 -QQGYGSAQGAPSQY 355
            Q G    +G PS Y
Sbjct: 128 PQHGNYQEEGPPSYY 142


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.123    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,930,089
Number of Sequences: 37866
Number of extensions: 874487
Number of successful extensions: 6132
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 286
Number of HSP's that attempted gapping in prelim test: 3350
Number of HSP's gapped (non-prelim): 1242
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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