BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|39777614 SS18-like protein 1 [Homo sapiens] (396 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|39777614 SS18-like protein 1 [Homo sapiens] 811 0.0 gi|56117846 synovial sarcoma translocation, chromosome 18 isofor... 485 e-137 gi|56117844 synovial sarcoma translocation, chromosome 18 isofor... 417 e-117 gi|10047104 synovial sarcoma translocation gene on chromosome 18... 94 3e-19 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 67 4e-11 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 67 4e-11 gi|62122917 filaggrin family member 2 [Homo sapiens] 66 6e-11 gi|57864582 hornerin [Homo sapiens] 65 8e-11 gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 65 1e-10 gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 63 5e-10 gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 63 5e-10 gi|171916097 repetin [Homo sapiens] 63 5e-10 gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 60 3e-09 gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 59 8e-09 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 59 8e-09 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 59 8e-09 gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 55 1e-07 gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 55 1e-07 gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 55 1e-07 gi|93141033 PAX interacting protein 1 [Homo sapiens] 54 2e-07 gi|31652242 transcription factor 20 isoform 2 [Homo sapiens] 54 2e-07 gi|31652244 transcription factor 20 isoform 1 [Homo sapiens] 54 2e-07 gi|60097902 filaggrin [Homo sapiens] 54 3e-07 gi|33286444 mastermind-like 2 [Homo sapiens] 52 7e-07 gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s... 52 1e-06 gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 52 1e-06 gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 52 1e-06 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 52 1e-06 gi|110347429 mediator complex subunit 12 [Homo sapiens] 50 4e-06 gi|57165375 glutamate receptor, ionotropic, N-methyl D-aspartate... 49 6e-06 >gi|39777614 SS18-like protein 1 [Homo sapiens] Length = 396 Score = 811 bits (2096), Expect = 0.0 Identities = 396/396 (100%), Positives = 396/396 (100%) Query: 1 MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY 60 MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY Sbjct: 1 MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY 60 Query: 61 LATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ 120 LATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ Sbjct: 61 LATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ 120 Query: 121 GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180 GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN Sbjct: 121 GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180 Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ Sbjct: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240 Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ Sbjct: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 Query: 301 HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360 HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ Sbjct: 301 HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360 Query: 361 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ Sbjct: 361 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 >gi|56117846 synovial sarcoma translocation, chromosome 18 isoform 1 [Homo sapiens] Length = 418 Score = 485 bits (1248), Expect = e-137 Identities = 251/419 (59%), Positives = 293/419 (69%), Gaps = 24/419 (5%) Query: 1 MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY 60 MSVAFA+ R RGKGE+T IQKMLD+N+HLIQCI++ Q+KGKT+EC+QYQQ+LH NLVY Sbjct: 1 MSVAFAAPRQRGKGEITPAAIQKMLDDNNHLIQCIMDSQNKGKTSECSQYQQMLHTNLVY 60 Query: 61 LATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ 120 LATIADSNQNMQSLLPAPPTQNM +GPG + QSG S SD + G PP+ +Q Sbjct: 61 LATIADSNQNMQSLLPAPPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQ 120 Query: 121 GQIGN---GPSHVSMQQTAPNTLPTTSMSISGP--------GYSHAGPASQGVPMQGQGT 169 Q+ GP+H+ MQ PN L T+ S++ P GY+H+ P+SQ +P+Q Q T Sbjct: 121 NQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGYNHSVPSSQSMPVQNQMT 180 Query: 170 ------IGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQS-SIAMMGQGSQ 222 +GNY R N++MQ N MM QQ + Y+ QGG QHYQGQ + MMGQ +Q Sbjct: 181 MSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGMMGQVNQ 240 Query: 223 GSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSH-SQGAAEPMGQQYYPDGHGDYAY 281 G+ MMGQR + PYRP QQG QQY GQE+YYG+QYSH QG E M QQYYPDGH DY Y Sbjct: 241 GNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPDGHNDYGY 300 Query: 282 QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTY--SQQQYPSQQSYP 339 QQ SY EQ YDR +E+S+QHYYEGGNSQY QQQ Y QG QQ Y QQQYP QQ YP Sbjct: 301 QQPSYPEQGYDRPYEDSSQHYYEGGNSQYGQQQDAY-QGPPPQQGYPPQQQQYPGQQGYP 359 Query: 340 GQQQGYGSAQGAPS-QYPGYQQGQGQQYGSYRAPQTA-PSAQQQRPYGYEQGQYGNYQQ 396 GQQQGYG +QG P QYP Y QGQGQQYG YR Q P QQRPYGY+QGQYGNYQQ Sbjct: 360 GQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRPYGYDQGQYGNYQQ 418 >gi|56117844 synovial sarcoma translocation, chromosome 18 isoform 2 [Homo sapiens] Length = 387 Score = 417 bits (1073), Expect = e-117 Identities = 229/419 (54%), Positives = 268/419 (63%), Gaps = 55/419 (13%) Query: 1 MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY 60 MSVAFA+ R RGKGE+T IQKMLD+N+HLIQCI++ Q+KGKT+EC+QYQQ+LH NLVY Sbjct: 1 MSVAFAAPRQRGKGEITPAAIQKMLDDNNHLIQCIMDSQNKGKTSECSQYQQMLHTNLVY 60 Query: 61 LATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ 120 LATIADSNQNMQSLLPAPPTQNM +GPG + QSG S SD + G PP+ +Q Sbjct: 61 LATIADSNQNMQSLLPAPPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQ 120 Query: 121 GQIGN---GPSHVSMQQTAPNTLPTTSMSISGP--------GYSHAGPASQGVPMQGQGT 169 Q+ GP+H+ MQ PN L T+ S++ P GY+H+ P+SQ +P+Q Q T Sbjct: 121 NQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGYNHSVPSSQSMPVQNQMT 180 Query: 170 I------GNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSS-IAMMGQGSQ 222 + GNY R N++MQ N MM QQ + Y+ QGG QHYQGQ + MMGQ +Q Sbjct: 181 MSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGMMGQVNQ 240 Query: 223 GSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHS-QGAAEPMGQQYYPDGHGDYAY 281 G+ MMGQR + PYRP QQG QQY GQE+YYG+QYSH QG E M QQYYPD Sbjct: 241 GNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPD------- 293 Query: 282 QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTY--SQQQYPSQQSYP 339 GNSQY QQQ YQ G QQ Y QQQYP QQ YP Sbjct: 294 ------------------------GNSQYGQQQDAYQ-GPPPQQGYPPQQQQYPGQQGYP 328 Query: 340 GQQQGYGSAQGAPS-QYPGYQQGQGQQYGSYRAPQTAP-SAQQQRPYGYEQGQYGNYQQ 396 GQQQGYG +QG P QYP Y QGQGQQYG YR Q P QQRPYGY+QGQYGNYQQ Sbjct: 329 GQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRPYGYDQGQYGNYQQ 387 >gi|10047104 synovial sarcoma translocation gene on chromosome 18-like 2 [Homo sapiens] Length = 77 Score = 93.6 bits (231), Expect = 3e-19 Identities = 44/73 (60%), Positives = 56/73 (76%) Query: 1 MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVY 60 MSVAF RGK EV Q+TIQ++L+EN LI+CI+EYQ+KG+ EC QYQ +LHRNL+Y Sbjct: 1 MSVAFVPDWLRGKAEVNQETIQRLLEENDQLIRCIVEYQNKGRGNECVQYQHVLHRNLIY 60 Query: 61 LATIADSNQNMQS 73 LATIAD++ S Sbjct: 61 LATIADASPTSTS 73 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 66.6 bits (161), Expect = 4e-11 Identities = 81/282 (28%), Positives = 106/282 (37%), Gaps = 31/282 (10%) Query: 121 GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGY--SHAGPASQGVPMQGQGTIGNYVSRTN 178 G G GP+ ++ Q + + SG SH P S G G G ++RT Sbjct: 323 GGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPG----SSGGGGQPLARTP 378 Query: 179 INMQSNPVSMMQQQAATSHYSSAQGGSQHY---QGQSSIAMMGQGSQGSSMMGQRPMAPY 235 S+P+ M + + GG+ Y QG S G G G Q P Y Sbjct: 379 --QPSSPMDQMGKMRPQPY-----GGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQR-Y 430 Query: 236 RPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSF 295 + QG +Q +G Y + + Q GQQ G Y QQS + +Q Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQ----GQTPYYNQQSPHPQQQQPPYS 486 Query: 296 EESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQ--QYPSQQS---YPGQQQGYGSAQG 350 ++ S Q Q+ Q + Q YSQQ Q P QQS YP QQ + Q Sbjct: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQS---TTQQ 543 Query: 351 APSQYPGYQQGQGQQ-YGSYRAPQTAPSA-QQQRPYGYEQGQ 390 P P Y Q Q Q Y + Q APS QQ Y Q Q Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQ 585 Score = 55.8 bits (133), Expect = 6e-08 Identities = 82/358 (22%), Positives = 125/358 (34%), Gaps = 54/358 (15%) Query: 65 ADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIG 124 ADS ++ + P P + ++ G T +S + G L P S + Sbjct: 1121 ADSKKSQPKIQPPSPAGSGSM-QGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGM 1179 Query: 125 NGPSHVSMQQT----APNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180 + + V +Q + +T + PGY P+ M G R + Sbjct: 1180 SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQ---PSMNTSDMMG---------RMSYE 1227 Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240 +P M++ + + S+ G G G G G+ MG R PY Sbjct: 1228 PNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGL-GNVAMGPRQHYPY----- 1281 Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGH----GDYAYQQSSYTEQSYDRSFE 296 G + E G + + S GA +P PD Y QQ +Q +D Sbjct: 1282 GGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGN 1341 Query: 297 ESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQY----PSQQSYPGQQQG--YGSAQG 350 + + G+ SQQ YQQ QQQ Y + P + + G+ Y + QG Sbjct: 1342 QFSTQGTPSGSPFPSQQTTMYQQ---QQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQG 1398 Query: 351 APSQY-----------------PGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391 P Q P QQ QYG+ P TA +A ++RP G Q Q+ Sbjct: 1399 QPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGN-AYPATATAATERRPAGGPQNQF 1455 Score = 35.0 bits (79), Expect = 0.12 Identities = 63/265 (23%), Positives = 87/265 (32%), Gaps = 73/265 (27%) Query: 72 QSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGL--PPSSLLQGQIGN---- 125 Q+ P Q P L+Q + SQ S A S PP L Q G+ Sbjct: 555 QAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASS 614 Query: 126 GPSHVSMQ----------QTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVS 175 PS S + Q+ P++LP S SI +PM +G + VS Sbjct: 615 APSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD------------LPMGTEGALSPGVS 662 Query: 176 RTNINM----QSNPVSMMQQQAATSHYSSAQGGSQHYQGQ-SSIAMMGQGSQGSSMMGQR 230 + I+ QSNP + H +G S G +S+A G + + Sbjct: 663 TSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN 722 Query: 231 PMAPYRPSQQGSS-------QQYLGQEEYYGE------QYS------------------- 258 M P PS Q S Q + Q+ Y + QYS Sbjct: 723 QMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIH 782 Query: 259 --------HSQGAAEPMGQQYYPDG 275 +S G+ P G QY P G Sbjct: 783 TGMGSYQQNSMGSYGPQGGQYGPQG 807 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 66.6 bits (161), Expect = 4e-11 Identities = 81/282 (28%), Positives = 106/282 (37%), Gaps = 31/282 (10%) Query: 121 GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGY--SHAGPASQGVPMQGQGTIGNYVSRTN 178 G G GP+ ++ Q + + SG SH P S G G G ++RT Sbjct: 323 GGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPG----SSGGGGQPLARTP 378 Query: 179 INMQSNPVSMMQQQAATSHYSSAQGGSQHY---QGQSSIAMMGQGSQGSSMMGQRPMAPY 235 S+P+ M + + GG+ Y QG S G G G Q P Y Sbjct: 379 --QPSSPMDQMGKMRPQPY-----GGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQR-Y 430 Query: 236 RPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSF 295 + QG +Q +G Y + + Q GQQ G Y QQS + +Q Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQ----GQTPYYNQQSPHPQQQQPPYS 486 Query: 296 EESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQ--QYPSQQS---YPGQQQGYGSAQG 350 ++ S Q Q+ Q + Q YSQQ Q P QQS YP QQ + Q Sbjct: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQS---TTQQ 543 Query: 351 APSQYPGYQQGQGQQ-YGSYRAPQTAPSA-QQQRPYGYEQGQ 390 P P Y Q Q Q Y + Q APS QQ Y Q Q Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQ 585 Score = 35.0 bits (79), Expect = 0.12 Identities = 63/265 (23%), Positives = 87/265 (32%), Gaps = 73/265 (27%) Query: 72 QSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGL--PPSSLLQGQIGN---- 125 Q+ P Q P L+Q + SQ S A S PP L Q G+ Sbjct: 555 QAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASS 614 Query: 126 GPSHVSMQ----------QTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVS 175 PS S + Q+ P++LP S SI +PM +G + VS Sbjct: 615 APSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD------------LPMGTEGALSPGVS 662 Query: 176 RTNINM----QSNPVSMMQQQAATSHYSSAQGGSQHYQGQ-SSIAMMGQGSQGSSMMGQR 230 + I+ QSNP + H +G S G +S+A G + + Sbjct: 663 TSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN 722 Query: 231 PMAPYRPSQQGSS-------QQYLGQEEYYGE------QYS------------------- 258 M P PS Q S Q + Q+ Y + QYS Sbjct: 723 QMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIH 782 Query: 259 --------HSQGAAEPMGQQYYPDG 275 +S G+ P G QY P G Sbjct: 783 TGMGSYQQNSMGSYGPQGGQYGPQG 807 Score = 33.9 bits (76), Expect = 0.26 Identities = 66/322 (20%), Positives = 101/322 (31%), Gaps = 65/322 (20%) Query: 65 ADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIG 124 ADS ++ + P P + ++ G T +S + G L P S + Sbjct: 1121 ADSKKSQPKIQPPSPAGSGSM-QGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGM 1179 Query: 125 NGPSHVSMQQT----APNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180 + + V +Q + +T + PGY P+ M G R + Sbjct: 1180 SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQ---PSMNTSDMMG---------RMSYE 1227 Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240 +P M++ + + S+ G G G G G+ MG R PY Sbjct: 1228 PNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGL-GNVAMGPRQHYPY----- 1281 Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 G + E G + + S GA +P PD G Y+ Sbjct: 1282 GGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDS-GMYS-------------------- 1320 Query: 301 HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360 S+Y QQ QQQ SY Q G+ G+P +P Q Sbjct: 1321 ------PSRYPPQQ-------------QQQQQQRHDSYGNQFSTQGTPSGSP--FPSQQT 1359 Query: 361 GQGQQYGSYRAPQTAPSAQQQR 382 QQ +P P + R Sbjct: 1360 TMYQQQQQVSSPAPLPRPMENR 1381 Score = 29.6 bits (65), Expect = 5.0 Identities = 24/102 (23%), Positives = 34/102 (33%), Gaps = 9/102 (8%) Query: 293 RSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAP 352 RS Q + G+ Q++ Q + + + SY + YGS + AP Sbjct: 1181 RSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAP 1240 Query: 353 SQYP------GYQQGQGQQYGSYRAP---QTAPSAQQQRPYG 385 P G G G Y P A +Q PYG Sbjct: 1241 GSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG 1282 >gi|62122917 filaggrin family member 2 [Homo sapiens] Length = 2391 Score = 65.9 bits (159), Expect = 6e-11 Identities = 86/309 (27%), Positives = 112/309 (36%), Gaps = 28/309 (9%) Query: 93 SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQ-QTAPNTLPTTSMSISGPG 151 SG S G GS S S+G GQ H S Q++ + S SG G Sbjct: 574 SGQSTGFGQYGSGSGQ-SSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYG 632 Query: 152 YSHAGPASQGVPMQGQGT-----IGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQ 206 H + G G G+ G Y S S S Q + S SS G + Sbjct: 633 -QHGSRQTSGFGQHGSGSSQSTGFGQYGSG------SGQSSGFGQHVSGSGQSSGFGQHE 685 Query: 207 HYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEP 266 G SS G GS SS GQ + + S G + GQ +G+ H G+ + Sbjct: 686 SRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQ---HGSGSGQS 742 Query: 267 MGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY-QQGAAQQQ 325 G + G G QSS Q RS + S G +S S Q +GY Q G+ Q Sbjct: 743 SGFGQHGSGSG-----QSSGFGQHESRSGQSSY-----GQHSSGSSQSSGYGQHGSRQTS 792 Query: 326 TYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYG 385 + Q S QS Q G GS Q A G GQ +G + + S Q Sbjct: 793 GFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGS 852 Query: 386 YEQGQYGNY 394 + YG + Sbjct: 853 SQSSGYGQH 861 Score = 60.1 bits (144), Expect = 3e-09 Identities = 89/331 (26%), Positives = 124/331 (37%), Gaps = 50/331 (15%) Query: 81 QNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQ----GQIGNGPSHVSMQQTA 136 Q+ G SS G HS GS S+G Q GQ G+G S Sbjct: 602 QSSGFGQHESRSGQSSYGQHSSGSSQ---SSGYGQHGSRQTSGFGQHGSGSSQ------- 651 Query: 137 PNTLPTTSMSISGPGYSHAGPASQGVPMQGQGT-IGNYVSRTNINMQ------SNPVSMM 189 +T G G + Q V GQ + G + SR+ + S+ S Sbjct: 652 -----STGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGY 706 Query: 190 QQQAATSHYSSAQGGSQHYQGQSS-IAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLG 248 Q ++S +S G + GQSS G GS SS GQ + S G + G Sbjct: 707 GQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSG 766 Query: 249 QEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNS 308 Q Y HS G+++ G+G + +Q+S Q S + + Y G Sbjct: 767 QSSY----GQHSSGSSQ-------SSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSG-- 813 Query: 309 QYSQQQAGYQQ---GAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ 365 S Q AG+ Q G+ Q + Q + S QS G Q G GS+Q + G GQ Sbjct: 814 --SGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYG-QHGSGSSQSSGYGQHGSSSGQTSG 870 Query: 366 YGSYRAPQTAPSAQQQRPYGYEQ----GQYG 392 +G +R+ S Q G Q GQ+G Sbjct: 871 FGQHRSSSGQYSGFGQHGSGSGQSSGFGQHG 901 Score = 57.8 bits (138), Expect = 2e-08 Identities = 84/309 (27%), Positives = 119/309 (38%), Gaps = 37/309 (11%) Query: 101 SQGSLSDAISTGLPPSSLLQGQI-GNGPSHVSMQQTAPNTLP-----TTSMSISGPGYSH 154 SQ + + TGL SS + + G+G + + T+ +L ++S SG G Sbjct: 424 SQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHG 483 Query: 155 AGPASQ---GVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQ 211 +G G G G + +++ QS S Q + S SS G + Q Sbjct: 484 SGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQS---SGFGQHGSVSGQSSGFGQHESRSRQ 540 Query: 212 SSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYG-EQYSHSQGAAEPMGQQ 270 SS G GS SS GQ G Q LG + G QY G + GQ Sbjct: 541 SSYGQHGSGSSQSSGYGQYGSR----ETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQ- 595 Query: 271 YYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY-QQGAAQQQTYSQ 329 HG + Q S + + S Q Y G +S S Q +GY Q G+ Q + Q Sbjct: 596 -----HGSGSGQSSGFGQHE-----SRSGQSSY-GQHSSGSSQSSGYGQHGSRQTSGFGQ 644 Query: 330 QQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYG-SYRAPQTAPSAQQQRPYGYEQ 388 S QS Q YGS G S + + G GQ G ++ S+ Q +G Q Sbjct: 645 HGSGSSQSTGFGQ--YGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQ 702 Query: 389 ----GQYGN 393 GQ+G+ Sbjct: 703 SSGYGQHGS 711 Score = 55.5 bits (132), Expect = 8e-08 Identities = 74/286 (25%), Positives = 96/286 (33%), Gaps = 22/286 (7%) Query: 93 SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGY 152 SG S G GS S S+G G+ H S + + N S S GY Sbjct: 955 SGQSSGFGQHGSGSGQ-SSGFGQHESGSGKSSGFGQHES-RSSQSNYGQHGSGSSQSSGY 1012 Query: 153 SHAGPASQGVPMQGQ--GTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG 210 G +S GQ + G Y S+ S Q S SS G + Sbjct: 1013 GQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSR 1072 Query: 211 QSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQ 270 QSS G GS SS GQ + S G + GQ +G QY G + GQ Sbjct: 1073 QSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFG-QYGSGSGQSSGFGQ- 1130 Query: 271 YYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQ 330 HG + S + + Y QH G S S ++ G+ ++ Q Sbjct: 1131 -----HGSGTGKSSGFAQHEYRSGQSSYGQH---GTGSSQSSGCGQHESGSGPTTSFGQH 1182 Query: 331 QYPSQQ--------SYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGS 368 S S GQ G+G Q G QG+ QQ S Sbjct: 1183 VSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVES 1228 Score = 54.7 bits (130), Expect = 1e-07 Identities = 89/339 (26%), Positives = 116/339 (34%), Gaps = 46/339 (13%) Query: 93 SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAP-NTLPTTSMSISGPG 151 SG S G S S S G S Q G G S QT+ ++S SG G Sbjct: 827 SGQSSGFGQHESRSHQSSYGQHGSGSSQSS-GYGQHGSSSGQTSGFGQHRSSSGQYSGFG 885 Query: 152 YSHAGPA-SQGVPMQGQGT-----IGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGS 205 +G S G G G+ G + SR++ + S Q + + S+ G + Sbjct: 886 QHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQT 945 Query: 206 ----QHYQGQ---SSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEY------ 252 QH G S G GS SS GQ + S G + Q Y Sbjct: 946 FGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSG 1005 Query: 253 ------YGEQYSHSQGAAEPMGQ------QYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 YG Q+ S G GQ QY G QSS Q S + S Sbjct: 1006 SSQSSGYG-QHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGF 1064 Query: 301 HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360 YE + Q S Q G G++Q Y Q S GQ G+G + Q G+ Q Sbjct: 1065 GQYESRSRQSSYGQHG--SGSSQSSGYGQ-----HGSNSGQTSGFGQHRPGSGQSSGFGQ 1117 Query: 361 -----GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNY 394 GQ +G + + S Q Y Q YG + Sbjct: 1118 YGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQH 1156 Score = 54.3 bits (129), Expect = 2e-07 Identities = 75/306 (24%), Positives = 103/306 (33%), Gaps = 39/306 (12%) Query: 95 SSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQ-QTAPNTLPTTSMSISGPGYS 153 SS G H GS S+G GQ H S Q++ + S SG G Sbjct: 730 SSFGQHGSGS---GQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYG-Q 785 Query: 154 HAGPASQGVPMQGQGT-----IGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208 H + G G G+ G Y S S + Q + S SS G + Sbjct: 786 HGSRQTSGFGQHGSGSSQSTGFGQYGSG------SGQSAGFGQHGSGSGQSSGFGQHESR 839 Query: 209 QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMG 268 QSS G GS SS GQ + + S G + GQ +G+ H G+ + G Sbjct: 840 SHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQ---HGSGSGQSSG 896 Query: 269 QQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYS 328 + G G Y+ QH S Y Q + G++Q Y Sbjct: 897 FGQHGTGSGQYS----------------GFGQHESRSHQSSYGQ----HGSGSSQSSGYG 936 Query: 329 QQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQ 388 Q S Q++ Q GS Q + G GQ +G + + S Q Q Sbjct: 937 QHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQ 996 Query: 389 GQYGNY 394 YG + Sbjct: 997 SNYGQH 1002 Score = 54.3 bits (129), Expect = 2e-07 Identities = 83/312 (26%), Positives = 110/312 (35%), Gaps = 28/312 (8%) Query: 93 SGSSQ--GLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGP 150 SGSSQ G GS S S G GQ H S + + S S Sbjct: 799 SGSSQSTGFGQYGSGSGQ-SAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSS- 856 Query: 151 GYSHAGPASQGVPMQGQ--GTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208 GY G +S GQ + G Y S S Q S S G + Sbjct: 857 GYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESR 916 Query: 209 QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMG 268 QSS G GS SS GQ + + G + GQ +G+ H G+ + G Sbjct: 917 SHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQ---HGSGSGQSSG 973 Query: 269 QQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY-QQGAAQQQTY 327 + G G +SS Q RS S +Y + G+ S Q +GY Q G++ QT Sbjct: 974 FGQHESGSG-----KSSGFGQHESRS---SQSNYGQHGSG--SSQSSGYGQHGSSSGQTT 1023 Query: 328 SQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ-----GQGQQYGSYRAPQTAPSAQQQR 382 Q+ S GQ G+G Q G+ Q GQ +G Y + S Q Sbjct: 1024 GFGQHRSSS---GQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHG 1080 Query: 383 PYGYEQGQYGNY 394 + YG + Sbjct: 1081 SGSSQSSGYGQH 1092 Score = 46.2 bits (108), Expect = 5e-05 Identities = 63/277 (22%), Positives = 97/277 (35%), Gaps = 19/277 (6%) Query: 121 GQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180 G+ G+G S S + T S G S G S+ + + GTI T Sbjct: 1722 GRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGE-SESIVHERHGTIHGQTGDTT-- 1778 Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240 + A + H S Q GS+ +SS S+G S QRP + Q Sbjct: 1779 ----------RHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQ 1828 Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 SQ G+ E ++ + + GHG SS T + E S Sbjct: 1829 AGSQH--GESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDS 1886 Query: 301 HYYEGG---NSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357 + GG +S ++ QA Q G ++ + + Q Q+ + G+ S G Q Sbjct: 1887 EVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPS-HGQTIQTGS 1945 Query: 358 YQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNY 394 G+ S + PS G+ GQ G++ Sbjct: 1946 RTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSH 1982 Score = 45.8 bits (107), Expect = 7e-05 Identities = 78/324 (24%), Positives = 112/324 (34%), Gaps = 27/324 (8%) Query: 92 QSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPG 151 + G G S G S P S Q G G Q T S S G Sbjct: 322 KGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCG 381 Query: 152 -YSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA--------- 201 Y G S G+ G + + ++ SN S Q + S S++ Sbjct: 382 QYGSGGSQSCSNGQHEYGSCGRFSNSSS----SNEFSKCDQYGSGSSQSTSFEQHGTGLS 437 Query: 202 --QGGSQHYQGQSSIAMMGQGSQGSSM-MGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYS 258 G QH G + + S+ Q + + S G GQ +G+ S Sbjct: 438 QSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGS 497 Query: 259 HSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQS--YDRSFEESTQHYYEGGNSQYSQQQAG 316 S G + GQ G Q S + QS + + S Q Y G + S Q +G Sbjct: 498 GS-GQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSY-GQHGSGSSQSSG 555 Query: 317 Y-QQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTA 375 Y Q G+ + + Q S QS Q G GS Q + G GQ +G + + ++ Sbjct: 556 YGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHES-RSG 614 Query: 376 PSAQQQRPYGYEQ----GQYGNYQ 395 S+ Q G Q GQ+G+ Q Sbjct: 615 QSSYGQHSSGSSQSSGYGQHGSRQ 638 Score = 38.1 bits (87), Expect = 0.014 Identities = 75/321 (23%), Positives = 109/321 (33%), Gaps = 67/321 (20%) Query: 90 LTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISG 149 ++ SG S G GS S STGL Q + G+ H + T T+ TT S SG Sbjct: 1196 ISDSGQSTGFGQYGSGSGQ-STGLGQGESQQVESGS-TVHGRQETTHGQTINTTRHSQSG 1253 Query: 150 PGYSHAGPASQGVPMQGQGT-IGNYVSRTNINMQS-NPVSMMQQQAATSH--YSSAQGGS 205 QGQ T G+ V+R + QS N S + + + H + Q GS Sbjct: 1254 ---------------QGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGS 1298 Query: 206 QHYQGQSSIAMMGQGS----------QGSSMMGQRPMAPYRPS---------------QQ 240 HY S QG+ G S GQ R S Sbjct: 1299 -HYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHS 1357 Query: 241 GSSQQYLGQEEYY---GEQYSHSQGAAEPMGQQYYPD----------GHGDYAYQQSSYT 287 G S + QE+ + G Q+ S+ + Y GHG + S T Sbjct: 1358 GVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTT 1417 Query: 288 EQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGS 347 + E S + GG+ + Q+ + Q +Q + + GQ Sbjct: 1418 GRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQ------ 1471 Query: 348 AQGAPSQYPGYQQGQGQQYGS 368 G +++ Y G+ Q GS Sbjct: 1472 -TGDTTRHAHYHHGKSTQRGS 1491 Score = 30.8 bits (68), Expect = 2.2 Identities = 42/189 (22%), Positives = 72/189 (38%), Gaps = 32/189 (16%) Query: 187 SMMQQQAATSH--YSSAQGGSQHYQGQSSIAMMGQGSQGSSM-------------MGQRP 231 S + +A+ +H ++ +Q GS+H Q SS G G QG++ GQ Sbjct: 2186 SEVHSEASPTHSGHTHSQAGSRHGQSGSS----GHGRQGTTHGQTGDTTRHAHYGYGQST 2241 Query: 232 MAPYRPS-QQGSSQQYLGQEEYYG----EQYSHSQGAAEPMGQQYYPDGHG--DYAYQQS 284 R + ++GS E + H QG A +Q HG + + Q+ Sbjct: 2242 QRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQT 2301 Query: 285 SYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQG 344 T + + +STQ S + + +Q ++++Q + Q SY + Sbjct: 2302 GDTTRHGHSGYGQSTQ------TGSRSSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYD 2355 Query: 345 YGSAQGAPS 353 YG PS Sbjct: 2356 YGHTGYGPS 2364 >gi|57864582 hornerin [Homo sapiens] Length = 2850 Score = 65.5 bits (158), Expect = 8e-11 Identities = 67/233 (28%), Positives = 89/233 (38%), Gaps = 15/233 (6%) Query: 148 SGPGYSHAGPASQGVPMQGQ--GTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGS 205 SG GYS G AS QG+ T G S + S S Q + SH++S +G Sbjct: 824 SGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRH 883 Query: 206 QHYQGQS-SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAA 264 GQS G GS S G+ R S G GQ +G + S Q + Sbjct: 884 GSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSG 943 Query: 265 EPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQ 324 HG + SSY EQ RS + S + G +S S + G+ Q Sbjct: 944 YTQ--------HGSGSGHSSSY-EQHGSRSGQSSRSEQH-GSSSGSSSSYGQHGSGSRQS 993 Query: 325 QTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPS 377 + Q S QS + +GS G S Y Y+ G G + S R P + S Sbjct: 994 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSG--WSSSRGPYESGS 1044 Score = 63.5 bits (153), Expect = 3e-10 Identities = 87/332 (26%), Positives = 118/332 (35%), Gaps = 34/332 (10%) Query: 91 TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGP 150 + SG S GS S S+G GQ G H S +++ S S Sbjct: 1642 SSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSS 1700 Query: 151 GYSHAGPASQGVPMQGQ---------------GTIGNYVSRTNINMQSNPVSMMQQQAAT 195 G+ G S P +G+ G SR +S S+ Q + Sbjct: 1701 GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 1760 Query: 196 SHYSSAQGGSQHYQGQSSIAMMGQ---GSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEY 252 S +SSA SQH G GQ S SS Q + + S G Q Sbjct: 1761 SGHSSAY--SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSS 1818 Query: 253 YGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYT--EQSYDRSFEESTQHYYEGGNSQY 310 YG+Q S S G + G+ GH Q S + S R S Q G + Sbjct: 1819 YGQQGSGS-GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 1877 Query: 311 SQQQAGYQQ---GAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQ--- 364 S Q +GY Q G+ +Y Q S QS G+Q +GS+ G+ S Y + G Q Sbjct: 1878 SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQ--HGSSSGSSSSYGQHGSGSRQSLG 1935 Query: 365 --QYGSYRAPQTAPSAQQQRPYGYEQGQYGNY 394 Q+GS +PS + + YG Y Sbjct: 1936 HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY 1967 Score = 63.5 bits (153), Expect = 3e-10 Identities = 88/327 (26%), Positives = 118/327 (36%), Gaps = 45/327 (13%) Query: 88 GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVS-MQQTAPNTLPTTSMS 146 G+ ++ S G H GS G SS GQ G+G S ++ ++S S Sbjct: 2542 GSGSRQSPSYGRHGSGS-------GRSSSS---GQHGSGLGESSGFGHHESSSGQSSSYS 2591 Query: 147 ISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQ 206 G G H+ Q GQ + G S S Q + S SS G Sbjct: 2592 QHGSGSGHSSGYGQHGSRSGQSSRGE-----RHGSSSGSSSHYGQHGSGSRQSSGHGRQG 2646 Query: 207 HYQGQS-SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265 GQS S G G SS GQ R S +G + LG +G+ H G+ Sbjct: 2647 SGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQ---HESGSGH 2703 Query: 266 PMGQQYYPDGHGDYAYQ--------QSSYTEQSYDRSFEESTQHYYEGGNSQ---YSQQQ 314 + G G + Q QSS +Q + + S+ + G+SQ Y + Sbjct: 2704 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHG 2763 Query: 315 AGYQQ---------GAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ 365 AG Q G+ Q +Y Q S QS Q G GS Q S G G Sbjct: 2764 AGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGS 2823 Query: 366 YGSY---RAPQTAP--SAQQQRPYGYE 387 GSY T+P Q+QR Y Y+ Sbjct: 2824 SGSYFLSFPSSTSPYEYVQEQRCYFYQ 2850 Score = 63.2 bits (152), Expect = 4e-10 Identities = 73/306 (23%), Positives = 108/306 (35%), Gaps = 21/306 (6%) Query: 88 GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSI 147 G+ + SSQG H S A S+G SS Q + H S + + +S S Sbjct: 365 GSGSGHSSSQGQHGSTS-GQASSSGQHGSSSRQSS--SYGQHESASRHSSGRGQHSSGSG 421 Query: 148 SGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQH 207 PG+ G S P GQ T S+ + +S + + S+H Sbjct: 422 QSPGHGQRGSGSGQSPSSGQ-------HGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEH 474 Query: 208 YQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPM 267 G + S G G R R +QGSS G YG+ H G+ + + Sbjct: 475 SSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSA---GSSSSYGQ---HGSGSRQSL 528 Query: 268 GQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTY 327 G + G G Q S + ++ +S+ + G S S + Y+ G+ Sbjct: 529 GHSRHGSGSG----QSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGL 584 Query: 328 SQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYE 387 Q+ S QS Q G S + G GQ G + A S+ Q G Sbjct: 585 GHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSS 644 Query: 388 Q-GQYG 392 Q +YG Sbjct: 645 QSSRYG 650 Score = 62.0 bits (149), Expect = 9e-10 Identities = 75/316 (23%), Positives = 114/316 (36%), Gaps = 25/316 (7%) Query: 88 GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVS-MQQTAPNTLPTTSMS 146 G+ ++ S G H GS G SS GQ G+G S ++ ++S S Sbjct: 1602 GSGSRQSPSYGRHGSGS-------GRSSSS---GQHGSGLGESSGFGHHESSSGQSSSYS 1651 Query: 147 ISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQ 206 G G H+ Q GQ + G S S Q + S SS G Sbjct: 1652 QHGSGSGHSSGYGQHGSRSGQSSRGE-----RHGSSSRSSSRYGQHGSGSRQSSGHGRQG 1706 Query: 207 HYQGQS-SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265 GQS S G G SS GQ R S +G + G +G+ H G+ Sbjct: 1707 SGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ---HESGSGH 1763 Query: 266 PMGQQYYPDGHGDYAYQ----QSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY-QQG 320 + G G + Q +S ++D+ + Q G + S Q + Y QQG Sbjct: 1764 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG 1823 Query: 321 AAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380 + Q+ S+ ++ S + +GS G S + G GQ G ++ + Sbjct: 1824 SGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1883 Query: 381 QRPYGYEQGQYGNYQQ 396 +G G +Y+Q Sbjct: 1884 YTQHGSGSGHSSSYEQ 1899 Score = 61.6 bits (148), Expect = 1e-09 Identities = 86/348 (24%), Positives = 124/348 (35%), Gaps = 37/348 (10%) Query: 76 PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQT 135 P + G G + SG S G GS S S+G GQ H S Sbjct: 690 PHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSH-SSGYRKHGSRSGQSSRSEQHGSSSGL 748 Query: 136 APNTLPTTSMSISGPGYSHAGPASQGVPMQGQ--------GTIGNYVSRTNINMQSNPVS 187 + + S S G+ G S P + + + G + S T+ + Sbjct: 749 SSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYE 808 Query: 188 MMQQQAAT--SHYS-SAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244 QA+ H S S QG SQH G +S QG GS+ GQ + S G S Sbjct: 809 SGSGQASGFGQHESGSGQGYSQH--GSASGHFSSQGRHGSTS-GQSSSSGQHDSSSGQSS 865 Query: 245 QYLGQEEYYGEQYS----HSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 Y GQ E S H G+ + G G G Q SY S+ Sbjct: 866 SY-GQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG----QSPSYGRHGSGSGRSSSSG 920 Query: 301 HYYEG-------GNSQYSQQQAGY-QQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAP 352 + G G+ S Q +GY Q G+ + S +Q+ S+ + + +GS+ G+ Sbjct: 921 RHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSS 980 Query: 353 SQYPGYQQGQGQ-----QYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQ 395 S Y + G Q Q+GS +PS + + YG Y+ Sbjct: 981 SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYR 1028 Score = 61.2 bits (147), Expect = 2e-09 Identities = 91/353 (25%), Positives = 132/353 (37%), Gaps = 58/353 (16%) Query: 88 GALTQSGSSQGLHSQGSLSDA------ISTGLPPS----------SLLQGQIGNGPSHVS 131 G+ ++S S G H GS + +G PS S GQ G+G S Sbjct: 1680 GSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS 1739 Query: 132 MQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQ 191 + P + S+ G S +G +S G G+ G++ S+ S S Q Sbjct: 1740 SR--GPYESRSGHSSVFGQHESGSGHSS-AYSQHGSGS-GHFCSQGQHGSTSGQSSTFDQ 1795 Query: 192 QAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEE 251 + +++ SS+ G QH G S + GQ GS GQ P S G S Y GQ Sbjct: 1796 EGSSTGQSSSHG--QHGSGSSQSSSYGQQGSGS---GQSPSRGRHGSGSGHSSSY-GQHG 1849 Query: 252 YYGEQYSHSQGA-AEPMGQQYYPDGHGDYAYQQSSYT------------EQSYDRSFEES 298 G +S S G GQ H ++Q S YT EQ RS + S Sbjct: 1850 S-GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 1908 Query: 299 TQHYY---EGGNSQYSQQQAGYQQ---------GAAQQQTYSQQQYPSQQSYPGQQQGYG 346 + G +S Y Q +G +Q G+ Q + S+ ++ S YG Sbjct: 1909 RGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYG 1968 Query: 347 SAQGAPSQYPGYQQGQGQQYG----SYRAPQTAPSAQQQRPYGYE--QGQYGN 393 S G S Y+ G G G R+ Q++ Q G+ GQ+G+ Sbjct: 1969 SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2021 Score = 61.2 bits (147), Expect = 2e-09 Identities = 75/316 (23%), Positives = 113/316 (35%), Gaps = 25/316 (7%) Query: 88 GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVS-MQQTAPNTLPTTSMS 146 G+ ++ S G H GS G SS GQ G G S ++ ++S S Sbjct: 2072 GSGSRQSPSYGRHGSGS-------GRSSSS---GQHGPGLGESSGFGHHESSSGQSSSYS 2121 Query: 147 ISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQ 206 G G H+ Q GQ + G S S Q + S SS G Sbjct: 2122 QHGSGSGHSSGYGQHGSRSGQSSRGE-----RHGSSSGSSSRYGQHGSGSRQSSGHGRQG 2176 Query: 207 HYQGQS-SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265 G S S G GS SS GQ R S +G + G +G+ H G+ Sbjct: 2177 SGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ---HESGSGH 2233 Query: 266 PMGQQYYPDGHGDYAYQ----QSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY-QQG 320 + G G + Q +S ++D+ + Q G + S Q + Y QQG Sbjct: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG 2293 Query: 321 AAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380 + Q+ S+ ++ S + +GS G S + G GQ G ++ + Sbjct: 2294 SGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 2353 Query: 381 QRPYGYEQGQYGNYQQ 396 +G G +Y+Q Sbjct: 2354 YTQHGSGSGHSSSYEQ 2369 Score = 60.5 bits (145), Expect = 3e-09 Identities = 88/343 (25%), Positives = 123/343 (35%), Gaps = 40/343 (11%) Query: 86 GPGALTQSG-----SSQGL---HSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAP 137 GPG SG SS G +SQ S+G GQ G H S ++ Sbjct: 2098 GPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS 2157 Query: 138 NTLPTTSMSISGPGYSHAGPASQGVPMQGQ---------------GTIGNYVSRTNINMQ 182 S S G+ G S P +G+ G SR + Sbjct: 2158 RYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESR 2217 Query: 183 SNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQ---GSQGSSMMGQRPMAPYRPSQ 239 S S+ Q + S +SSA SQH G GQ S SS Q + + S Sbjct: 2218 SGHSSVFGQHESGSGHSSAY--SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275 Query: 240 QGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYT--EQSYDRSFEE 297 G Q YG+Q S S G + G+ GH Q S + S R Sbjct: 2276 HGQHGSGSSQSSSYGQQGSGS-GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 2334 Query: 298 STQHYYEGGNSQYSQQQAGY-QQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYP 356 S Q G + S Q +GY Q G+ + S +Q+ S+ + + +GS+ G+ S Y Sbjct: 2335 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYG 2394 Query: 357 GYQQGQGQ-----QYGSYRAPQTAPSAQQQRPYGYEQGQYGNY 394 + G Q Q+GS +PS + +G GQ +Y Sbjct: 2395 QHGSGSRQSLGHGQHGSGSGQSPSPSRGR---HGSGSGQSSSY 2434 Score = 60.5 bits (145), Expect = 3e-09 Identities = 90/354 (25%), Positives = 131/354 (37%), Gaps = 60/354 (16%) Query: 88 GALTQSGSSQGLHSQGSLSDA------ISTGLPPSSLLQGQIGNGPSHVSMQ-------- 133 G+ + S S G H GS + +G PS +G+ G+G H S Sbjct: 2150 GSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPS---RGRHGSGSGHSSSHGQHGSGSG 2206 Query: 134 ---QTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQ 190 P + S+ G S +G +S G G+ G++ S+ S S Sbjct: 2207 RSSSRGPYESRSGHSSVFGQHESGSGHSS-AYSQHGSGS-GHFCSQGQHGSTSGQSSTFD 2264 Query: 191 QQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQE 250 Q+ +++ SS+ G QH G S + GQ GS GQ P S G S Y GQ Sbjct: 2265 QEGSSTGQSSSHG--QHGSGSSQSSSYGQQGSGS---GQSPSRGRHGSGSGHSSSY-GQH 2318 Query: 251 EYYGEQYSHSQGA-AEPMGQQYYPDGHGDYAYQQSSYT------------EQSYDRSFEE 297 G +S S G GQ H ++Q S YT EQ RS + Sbjct: 2319 GS-GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQS 2377 Query: 298 STQHYY---EGGNSQYSQQQAGYQQ---------GAAQQQTYSQQQYPSQQSYPGQQQGY 345 S + G +S Y Q +G +Q G+ Q + S+ ++ S Y Sbjct: 2378 SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPY 2437 Query: 346 GSAQGAPSQYPGYQQGQGQQYG----SYRAPQTAPSAQQQRPYGYE--QGQYGN 393 GS G S Y+ G G G R+ Q++ Q G+ GQ+G+ Sbjct: 2438 GSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2491 Score = 58.9 bits (141), Expect = 8e-09 Identities = 83/312 (26%), Positives = 114/312 (36%), Gaps = 25/312 (8%) Query: 91 TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQ-TAPNTLPTTSMSISG 149 ++ S +G HS GS G P +G G+G S S Q T ++ +SG Sbjct: 407 SRHSSGRGQHSSGS-------GQSPGHGQRGS-GSGQSPSSGQHGTGFGRSSSSGPYVSG 458 Query: 150 PGYSH-------AGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQ 202 GYS + S G G G+ G+ +S S ++Q +++ SS+ Sbjct: 459 SGYSSGFGHHESSSEHSSGYTQHGSGS-GHSSGHGQHGSRSGQSSRGERQGSSAGSSSSY 517 Query: 203 GGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQG 262 G QH G S +G GS GQ P + GS Q YG S S+G Sbjct: 518 G--QH--GSGSRQSLGHSRHGSGS-GQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG 572 Query: 263 AAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA 322 E GH + QSS Q S ST H G S S + + Sbjct: 573 PYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSST-HGQHGSTSGQSSSCGQHGATSG 631 Query: 323 QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQR 382 Q ++ Q S QS QQG GS Q G G YG + + S+ Sbjct: 632 QSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSS--NG 689 Query: 383 PYGYEQGQYGNY 394 P+G GQ + Sbjct: 690 PHGSVSGQSSGF 701 Score = 58.5 bits (140), Expect = 1e-08 Identities = 85/332 (25%), Positives = 115/332 (34%), Gaps = 33/332 (9%) Query: 92 QSGSSQG---LHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSIS 148 Q GSS G H Q + S+ GQ + H S + S S Sbjct: 2475 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 2534 Query: 149 GPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208 PG+ G S+ P G+ G+ R++ + Q S + + + H+ S+ G S Y Sbjct: 2535 SPGHGQRGSGSRQSPSYGRHGSGS--GRSSSSGQHG--SGLGESSGFGHHESSSGQSSSY 2590 Query: 209 --QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQY------LGQEEYYGEQYSHS 260 G S G G G S GQ S GSS Y Q +G Q S S Sbjct: 2591 SQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 2649 Query: 261 QGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEEST--------QHYYEGGNSQ-YS 311 G + G+ GH Q S + +S R ES QH G+S YS Sbjct: 2650 -GQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYS 2708 Query: 312 QQQAG----YQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ---GQGQ 364 Q +G QG + + + S GQ YG SQ GY + G GQ Sbjct: 2709 QHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQ 2768 Query: 365 QYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 R + + +G GQ Y Q Sbjct: 2769 SLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQ 2800 Score = 58.2 bits (139), Expect = 1e-08 Identities = 81/304 (26%), Positives = 114/304 (37%), Gaps = 20/304 (6%) Query: 93 SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGY 152 SG S G +GS +G PS G+ G+G S + ++ + S SG G+ Sbjct: 887 SGQSPGHGQRGS-----GSGQSPS---YGRHGSG----SGRSSSSGRHGSGSGQSSGFGH 934 Query: 153 SHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQS 212 + S G G G+ G+ S +S S +Q ++S SS+ G QH G Sbjct: 935 KSSSGQSSGYTQHGSGS-GHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYG--QH--GSG 989 Query: 213 SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYY 272 S +G G GS GQ P GS Q G +S S+G E Sbjct: 990 SRQSLGHGQHGSGS-GQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSS 1048 Query: 273 PDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQY 332 GH + QSS Q S ST H G S S + + Q ++ Q Sbjct: 1049 GLGHRESRSGQSSGYGQHGSSSGHSST-HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGS 1107 Query: 333 PSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGY-EQGQY 391 S QS +QG GS Q G Q YG + + S+ Q G E + Sbjct: 1108 GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGF 1167 Query: 392 GNYQ 395 G+++ Sbjct: 1168 GHHE 1171 Score = 58.2 bits (139), Expect = 1e-08 Identities = 79/317 (24%), Positives = 116/317 (36%), Gaps = 29/317 (9%) Query: 92 QSGSSQG---LHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSIS 148 Q GSS G H Q + S+ GQ + H S + S S Sbjct: 2005 QHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 2064 Query: 149 GPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208 PG+ G S+ P G+ G+ R++ + Q P + + + H+ S+ G S Y Sbjct: 2065 SPGHGQRGSGSRQSPSYGRHGSGS--GRSSSSGQHGP--GLGESSGFGHHESSSGQSSSY 2120 Query: 209 --QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQY------LGQEEYYGEQYSHS 260 G S G G G S GQ S GSS +Y Q +G Q S S Sbjct: 2121 SQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGS 2179 Query: 261 QGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQG 320 G + G+ GH Q S + +S R ES G +S + Q ++ G Sbjct: 2180 -GHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESR----SGHSSVFGQ----HESG 2230 Query: 321 AAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380 + YSQ S Q G S Q + G GQ +G + + + S+ Sbjct: 2231 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYG 2290 Query: 381 QRPYGYEQ----GQYGN 393 Q+ G Q G++G+ Sbjct: 2291 QQGSGSGQSPSRGRHGS 2307 Score = 57.4 bits (137), Expect = 2e-08 Identities = 90/339 (26%), Positives = 126/339 (37%), Gaps = 43/339 (12%) Query: 88 GALTQSGSSQGLHSQGSLSDAISTGLPPS----SLLQGQIGNGPSHVSMQ---------Q 134 G+ T SS G H GS S + S G S S +G+ G+G H S Sbjct: 1797 GSSTGQSSSHGQHGSGS-SQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS 1855 Query: 135 TAPNTLPTTSMSISGPGYSHAGP-ASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQA 193 ++ + S SG G+ + S G G G+ G+ S +S S +Q Sbjct: 1856 SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS-GHSSSYEQHGSRSGQSSRGEQHG 1914 Query: 194 ATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYY 253 ++S SS+ G QH G S +G G GS GQ P +P R + GS GQ Y Sbjct: 1915 SSSGSSSSYG--QH--GSGSRQSLGHGQHGSGS-GQSP-SPSR-GRHGSGS---GQSSSY 1964 Query: 254 GEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQS-----YDRSFEESTQHYYEGGNS 308 G Y G + G GH + S + QS + S S+ H G S Sbjct: 1965 GP-YGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSAS 2023 Query: 309 QYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYG- 367 S + + Q ++ Q S QS +QG GS Q G Q YG Sbjct: 2024 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 2083 Query: 368 -------SYRAPQTAPSAQQQRPYGYEQ---GQYGNYQQ 396 S + Q P + +G+ + GQ +Y Q Sbjct: 2084 HGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122 Score = 56.6 bits (135), Expect = 4e-08 Identities = 74/296 (25%), Positives = 106/296 (35%), Gaps = 29/296 (9%) Query: 119 LQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTN 178 ++G + G +S + + S SG S+ S G+G G+ ++ Sbjct: 144 VRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSP 203 Query: 179 INMQSNPVSMMQQQAATSHYSSAQ--GGSQHYQ--GQSS-IAMMGQGSQGSSMMGQRPMA 233 Q S T S Q G SQH GQSS + G GS SS GQ Sbjct: 204 NYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSR 263 Query: 234 PYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDG---------HGDYAYQQS 284 + S+ + G YG+ H G+ + +G G HG + S Sbjct: 264 SGQSSRGERHRSSSGSSSSYGQ---HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSS 320 Query: 285 SYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQ---GAAQQQTYSQQQYPSQQSYPGQ 341 S+ + S+ S HY G S Q +G+ Q G+ Q YS+ S S Sbjct: 321 SHGQHGSGSSYSYSRGHYESG-----SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQG 375 Query: 342 QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQ----GQYGN 393 Q G S Q + S G Q YG + + S + Q G Q GQ G+ Sbjct: 376 QHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGS 431 Score = 56.6 bits (135), Expect = 4e-08 Identities = 79/311 (25%), Positives = 118/311 (37%), Gaps = 26/311 (8%) Query: 88 GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSI 147 G+ + S SS G H GS SL GQ G+G + + S Sbjct: 974 GSSSGSSSSYGQHGSGSRQ----------SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 1023 Query: 148 SGPGYSHAGPASQGVPMQ-GQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQ 206 GP S +G +S P + G G R + + QS+ Q ++S +SS G Sbjct: 1024 YGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG---QHGSSSGHSSTHGQHG 1080 Query: 207 HYQGQSS-IAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265 GQSS G S SS GQ + S G GQ +G++ S S+ + Sbjct: 1081 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 1140 Query: 266 PMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQ 325 G+ G + Q S +S ES+ G +S YSQ + G+ Sbjct: 1141 -YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS----GQSSSYSQ----HGSGSGHSS 1191 Query: 326 TYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYG 385 Y Q S QS G++ +GS+ G+ S Y + G Q G R + + + +G Sbjct: 1192 GYGQHGSRSGQSSRGER--HGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG 1249 Query: 386 YEQGQYGNYQQ 396 G ++ Q Sbjct: 1250 SGLGHSSSHGQ 1260 Score = 56.6 bits (135), Expect = 4e-08 Identities = 70/299 (23%), Positives = 101/299 (33%), Gaps = 29/299 (9%) Query: 92 QSGSSQG---LHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSIS 148 Q GSS G H Q + S+ GQ + H S + S S Sbjct: 1065 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 1124 Query: 149 GPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208 PG+ G S+ P G+ G+ R++ + Q S + + + H+ S+ G S Y Sbjct: 1125 SPGHGQRGSGSRQSPSYGRHGSGS--GRSSSSGQHG--SGLGESSGFGHHESSSGQSSSY 1180 Query: 209 QGQSSIAMMGQG-SQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPM 267 S G G S G G R R + GSS G +YG+ H G+ + Sbjct: 1181 SQHGS----GSGHSSGYGQHGSRSGQSSRGERHGSSS---GSSSHYGQ---HGSGSRQSS 1230 Query: 268 GQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTY 327 G G G S + + S+ H G S S + Y+ + + Sbjct: 1231 GHGRQGSGSG------HSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF 1284 Query: 328 SQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGY 386 Q + S S Q G GS G GQ + Q S Q YG+ Sbjct: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF-----DQEGSSTGQSSSYGH 1338 Score = 56.6 bits (135), Expect = 4e-08 Identities = 85/323 (26%), Positives = 119/323 (36%), Gaps = 23/323 (7%) Query: 88 GALTQSGSSQGLHSQGSLSDAISTGLPPS----SLLQGQIGNGPSHVSMQ---------Q 134 G+ T SS G H GS S + S G S S +G+ G+G H S Sbjct: 2267 GSSTGQSSSHGQHGSGS-SQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS 2325 Query: 135 TAPNTLPTTSMSISGPGYSHAGP-ASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQA 193 ++ + S SG G+ + S G G G+ G+ S +S S ++ Sbjct: 2326 SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS-GHSSSYEQHGSRSGQSSRGERHG 2384 Query: 194 ATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYY 253 ++S SS+ G QH G S +G G GS GQ P GS Q Sbjct: 2385 SSSGSSSSYG--QH--GSGSRQSLGHGQHGSGS-GQSPSPSRGRHGSGSGQSSSYSPYGS 2439 Query: 254 GEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQ 313 G +S S+G E GH + QSS Q S ST H G S S Sbjct: 2440 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST-HGQHGSTSGQSSS 2498 Query: 314 QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQ 373 + + Q ++ Q S QS +QG GS Q G Q YG + + Sbjct: 2499 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 2558 Query: 374 TAPSAQQQRPYGY-EQGQYGNYQ 395 S+ Q G E +G+++ Sbjct: 2559 GRSSSSGQHGSGLGESSGFGHHE 2581 Score = 55.5 bits (132), Expect = 8e-08 Identities = 79/312 (25%), Positives = 111/312 (35%), Gaps = 11/312 (3%) Query: 93 SGSSQGLHSQGSLSDAISTG-----LPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSI 147 SG S G GS S S G SS GQ G+G S S+ + + S S Sbjct: 485 SGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSG-SRQSLGHSRHGSGSGQSPSP 543 Query: 148 SGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQH 207 S + S G G+ G SR S S + Q + S SS G Sbjct: 544 SRGRHESGSRQSSSYGPHGYGS-GRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGS 602 Query: 208 YQGQSSI-AMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEP 266 G SS G S SS GQ + S G Q YG+Q S S G + Sbjct: 603 SSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGS-GQSPS 661 Query: 267 MGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEG-GNSQYSQQQAGYQQ-GAAQQ 324 G+ GH Q S + S S G G+ S Q +GY Q G+ Sbjct: 662 RGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSS 721 Query: 325 QTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPY 384 + +++ S+ + + +GS+ G S Y + G Q G R + + + + Sbjct: 722 HSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRH 781 Query: 385 GYEQGQYGNYQQ 396 G G ++ Q Sbjct: 782 GSSSGHSSSHGQ 793 Score = 54.7 bits (130), Expect = 1e-07 Identities = 80/330 (24%), Positives = 123/330 (37%), Gaps = 33/330 (10%) Query: 91 TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGP 150 + SG S GS S S+G GQ G H S ++ + S S Sbjct: 1172 SSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 1230 Query: 151 GYSHAGPASQGVPMQGQ--GTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208 G+ G S P +G+ +G+ S S S + S +SS G + Sbjct: 1231 GHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 1290 Query: 209 QGQSS-IAMMGQGSQGSSMMGQRPMAPYRPS---QQGSSQQYLGQEEYYGEQYSHSQGAA 264 G SS + G GS GQ + S Q+GSS GQ YG + S S ++ Sbjct: 1291 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSS---TGQSSSYGHRGSGSSQSS 1347 Query: 265 ------EPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEG-------GNSQYS 311 GQ HG + SSY + + S+ + G G+ + S Sbjct: 1348 GYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 1407 Query: 312 QQQAG--YQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQ----- 364 Q+ Q G+ + S +Q+ S+ + + +GS+ G+ S Y + G Q Sbjct: 1408 SWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 1467 Query: 365 QYGSYRAPQTAPSAQQQRPYGYEQGQYGNY 394 Q+GS +PS + +G GQ +Y Sbjct: 1468 QHGSGSGQSPSPSRGR---HGSGSGQSSSY 1494 Score = 54.3 bits (129), Expect = 2e-07 Identities = 74/306 (24%), Positives = 106/306 (34%), Gaps = 22/306 (7%) Query: 88 GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSI 147 G+ + SSQG H S + S+G SS GQ + H S A S S Sbjct: 832 GSASGHFSSQGRHGSTS-GQSSSSGQHDSS--SGQSSSYGQHESASHHASGRGRHGSGSG 888 Query: 148 SGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQH 207 PG+ G S P G+ G+ S ++ S Q + H SS+ S + Sbjct: 889 QSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGS----GQSSGFGHKSSSGQSSGY 944 Query: 208 YQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPM 267 Q S Q S GQ + S GSS Y GQ H G+ + + Sbjct: 945 TQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSY-GQ---------HGSGSRQSL 994 Query: 268 GQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTY 327 G + G G Q S + + +S+ + S +S + Y+ G+ Sbjct: 995 GHGQHGSGSG----QSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGL 1050 Query: 328 SQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYE 387 ++ S QS Q G S + G GQ G + A S+ Q G Sbjct: 1051 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1110 Query: 388 QGQ-YG 392 Q YG Sbjct: 1111 QSSGYG 1116 Score = 54.3 bits (129), Expect = 2e-07 Identities = 76/311 (24%), Positives = 111/311 (35%), Gaps = 17/311 (5%) Query: 92 QSGSSQG---LHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSIS 148 Q GSS G H Q + S+ GQ + H S + S S Sbjct: 1535 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 1594 Query: 149 GPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHY 208 PG+ G S+ P G+ G+ R++ + Q S + + + H+ S+ G S Y Sbjct: 1595 SPGHGQRGSGSRQSPSYGRHGSGS--GRSSSSGQHG--SGLGESSGFGHHESSSGQSSSY 1650 Query: 209 --QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEP 266 G S G G G S GQ S SS +Y GQ Q S Sbjct: 1651 SQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSSRSSSRY-GQHGSGSRQSSGHGRQGSG 1708 Query: 267 MGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQT 326 GQ HG SS+ + S S++ YE S +S ++ G+ Sbjct: 1709 SGQSPSRGRHGSGLGHSSSHGQHG-SGSGRSSSRGPYE-SRSGHSSVFGQHESGSGHSSA 1766 Query: 327 YSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGY 386 YSQ S Q G S Q + G GQ +G + + + S+ Q+ G Sbjct: 1767 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS 1826 Query: 387 EQ----GQYGN 393 Q G++G+ Sbjct: 1827 GQSPSRGRHGS 1837 Score = 53.9 bits (128), Expect = 2e-07 Identities = 71/305 (23%), Positives = 104/305 (34%), Gaps = 34/305 (11%) Query: 92 QSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQ-QTAPNTLPTTSMSISGP 150 Q GS+ G S A S S GQ G+G S S Q + + S G Sbjct: 612 QHGSTSGQSSSCGQHGATSG----QSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGS 667 Query: 151 GYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG 210 + H+ +S G G G + +++ QS+ +S YS GS H Sbjct: 668 DFGHS--SSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSH--- 722 Query: 211 QSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQ 270 S G G R R Q GSS G YG+ H G+ + G Sbjct: 723 ----------SSGYRKHGSRSGQSSRSEQHGSSS---GLSSSYGQ---HGSGSHQSSGHG 766 Query: 271 YYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQ 330 G G S + + S S+ H G + S Y+ G+ Q + Q Sbjct: 767 RQGSGSG------HSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQH 820 Query: 331 QYPSQQSYP--GQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQ 388 + S Q Y G G+ S+QG G GQ S + + + + Sbjct: 821 ESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGR 880 Query: 389 GQYGN 393 G++G+ Sbjct: 881 GRHGS 885 Score = 53.9 bits (128), Expect = 2e-07 Identities = 82/314 (26%), Positives = 115/314 (36%), Gaps = 24/314 (7%) Query: 93 SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQ---------QTAPNTLPTT 143 SGSSQ S G +G PS +G+ G+G H S ++ + Sbjct: 1341 SGSSQ---SSGYGRHGAGSGQSPS---RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1394 Query: 144 SMSISGPGYSHAGP-ASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQ 202 S SG G+ + S G G G+ G+ S +S S ++ ++S SS+ Sbjct: 1395 SGQSSGFGHHESSSWQSSGCTQHGSGS-GHSSSYEQHGSRSGQSSRGERHGSSSGSSSSY 1453 Query: 203 GGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQG 262 G QH G S +G G GS GQ P GS Q G +S S+G Sbjct: 1454 G--QH--GSGSRQSLGHGQHGSGS-GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG 1508 Query: 263 AAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA 322 E GH + QSS Q S ST H G S S + + Sbjct: 1509 PYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST-HGQHGSTSGQSSSCGQHGASSG 1567 Query: 323 QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQR 382 Q ++ Q S QS +QG GS Q G Q YG + + S+ Q Sbjct: 1568 QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 1627 Query: 383 PYGY-EQGQYGNYQ 395 G E +G+++ Sbjct: 1628 GSGLGESSGFGHHE 1641 Score = 53.5 bits (127), Expect = 3e-07 Identities = 74/292 (25%), Positives = 102/292 (34%), Gaps = 34/292 (11%) Query: 120 QGQIGNGPSHVS-MQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTN 178 QGQ G+ S Q +T ++S G G S + Q QG G+ G SR Sbjct: 1780 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQ----QGSGS-GQSPSRGR 1834 Query: 179 INMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSS--------------IAMMGQGSQGS 224 S S Q + S +SS+ G GQSS G GS S Sbjct: 1835 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 1894 Query: 225 SMM---GQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAY 281 S G R R Q GSS G YG+ H G+ + +G + G G Sbjct: 1895 SSYEQHGSRSGQSSRGEQHGSSS---GSSSSYGQ---HGSGSRQSLGHGQHGSGSG---- 1944 Query: 282 QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQ 341 Q S + + +S+ + G S +S + Y+ G+ ++ S QS Sbjct: 1945 QSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG 2004 Query: 342 QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQ-YG 392 Q G S + G GQ G + A S+ Q G Q YG Sbjct: 2005 QHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 2056 Score = 52.4 bits (124), Expect = 7e-07 Identities = 77/331 (23%), Positives = 111/331 (33%), Gaps = 36/331 (10%) Query: 91 TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGP 150 + SG S G GS S S+G GQ G H S ++ + S S Sbjct: 236 SSSGQSSGYSQHGSGSGH-SSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSL 294 Query: 151 GYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG 210 G+ G S+ P + G+ S ++ S + S G QH G Sbjct: 295 GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESG 354 Query: 211 Q---SSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYS--------- 258 S + G GS SS GQ + S G Q YG+ S Sbjct: 355 SGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414 Query: 259 -HSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGG--------NSQ 309 HS G+ + G G G Q S + S+ Y G + Sbjct: 415 QHSSGSGQSPGHGQRGSGSG----QSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHES 470 Query: 310 YSQQQAGYQQ---GAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQ-- 364 S+ +GY Q G+ + Q S QS G++Q GS+ G+ S Y + G Q Sbjct: 471 SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQ--GSSAGSSSSYGQHGSGSRQSL 528 Query: 365 ---QYGSYRAPQTAPSAQQQRPYGYEQGQYG 392 ++GS +PS + + YG Sbjct: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYG 559 Score = 52.4 bits (124), Expect = 7e-07 Identities = 73/292 (25%), Positives = 102/292 (34%), Gaps = 34/292 (11%) Query: 120 QGQIGNGPSHVS-MQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTN 178 QGQ G+ S Q +T ++S G G S + Q QG G+ G SR Sbjct: 2250 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQ----QGSGS-GQSPSRGR 2304 Query: 179 INMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSS--------------IAMMGQGSQGS 224 S S Q + S +SS+ G GQSS G GS S Sbjct: 2305 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 2364 Query: 225 SMM---GQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAY 281 S G R R + GSS G YG+ H G+ + +G + G G Sbjct: 2365 SSYEQHGSRSGQSSRGERHGSSS---GSSSSYGQ---HGSGSRQSLGHGQHGSGSG---- 2414 Query: 282 QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQ 341 Q S + + +S+ + G S +S + Y+ G+ ++ S QS Sbjct: 2415 QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG 2474 Query: 342 QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQ-YG 392 Q G S + G GQ G + A S+ Q G Q YG Sbjct: 2475 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 2526 Score = 52.0 bits (123), Expect = 9e-07 Identities = 73/292 (25%), Positives = 102/292 (34%), Gaps = 34/292 (11%) Query: 120 QGQIGNGPSHVS-MQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTN 178 QGQ G+ S Q +T ++S G G S S G G G+ G SR Sbjct: 1310 QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQ----SSGYGRHGAGS-GQSPSRGR 1364 Query: 179 INMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSS--------------IAMMGQGSQGS 224 S S Q + S +SS+ G GQSS G GS S Sbjct: 1365 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHS 1424 Query: 225 SMM---GQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAY 281 S G R R + GSS G YG+ H G+ + +G + G G Sbjct: 1425 SSYEQHGSRSGQSSRGERHGSSS---GSSSSYGQ---HGSGSRQSLGHGQHGSGSG---- 1474 Query: 282 QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQ 341 Q S + + +S+ + G S +S + Y+ G++ ++ S QS Sbjct: 1475 QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYG 1534 Query: 342 QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQ-YG 392 Q G S + G GQ G + A S+ Q G Q YG Sbjct: 1535 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 1586 Score = 48.5 bits (114), Expect = 1e-05 Identities = 75/307 (24%), Positives = 107/307 (34%), Gaps = 32/307 (10%) Query: 95 SSQGLHSQGSLSDAISTGLPPSSLLQG----QIGNGPSHVSMQQTAPNTLPTTSMSISGP 150 SS G H GS + G SS Q Q G+G H S + + + S G Sbjct: 1386 SSSGRHGSGS-GQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSR---SGQSSRGE 1441 Query: 151 GYSHAGPASQGVPMQGQGTIGNYVSRTNINM-QSNPVSMMQQQAATSHYSSAQGGSQHYQ 209 + + +S G G SR ++ Q S + + S G S Sbjct: 1442 RHGSSSGSSSSYGQHGSG------SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS---- 1491 Query: 210 GQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQ 269 SS + G GS SS G S G + GQ YG Q+ S G + GQ Sbjct: 1492 --SSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYG-QHGSSSGHSSTHGQ 1548 Query: 270 QYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQ 329 HG + Q SS + + S +S+ H G S S G+ Q + Q Sbjct: 1549 ------HGSTSGQSSSCGQ--HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 1600 Query: 330 QQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQG 389 + S+QS + G GS G S + G G+ G ++ + +G G Sbjct: 1601 RGSGSRQSPSYGRHGSGS--GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 1658 Query: 390 QYGNYQQ 396 Y Q Sbjct: 1659 HSSGYGQ 1665 >gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] Length = 592 Score = 64.7 bits (156), Expect = 1e-10 Identities = 62/192 (32%), Positives = 82/192 (42%), Gaps = 25/192 (13%) Query: 196 SHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQR--PMAPYRPSQQGSSQQYLGQEEYY 253 S+ + GSQ Y GQ+S + G G S GQ + Y SQ G SQ Y G E Sbjct: 16 SYSTYGNPGSQGY-GQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQ- 73 Query: 254 GEQYSHSQGAAEPMGQQYYPDGHG------------DYAYQQSSYTEQS-YDR---SFEE 297 +Q S+SQ GQQ + G DY QQ SY +QS YD+ S++E Sbjct: 74 -KQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG-QQDSYDQQSGYDQHQGSYDE 131 Query: 298 STQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357 Q Y+ + YSQ Q Y ++Q Y +GYG +QG G Sbjct: 132 --QSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGG 189 Query: 358 Y-QQGQGQQYGS 368 Y + G+G GS Sbjct: 190 YDKDGRGPMTGS 201 Score = 54.3 bits (129), Expect = 2e-07 Identities = 46/147 (31%), Positives = 60/147 (40%), Gaps = 23/147 (15%) Query: 258 SHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY 317 S+ Q E Y + G Y Q+S + Y ++ + S Y G +S Y Q Q+GY Sbjct: 6 SYGQSGGEQQSYSTYGNP-GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS-YGQSQSGY 63 Query: 318 QQGAA-----QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP 372 Q +Q +YSQQ Y +Q GQQQ S+ + P Y Q Q SY Sbjct: 64 SQSYGGYENQKQSSYSQQPYNNQ----GQQQNMESSGSQGGRAPSYDQPDYGQQDSY--- 116 Query: 373 QTAPSAQQQRPYGYEQGQY---GNYQQ 396 QQ Y QG Y NY Q Sbjct: 117 ------DQQSGYDQHQGSYDEQSNYDQ 137 >gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo sapiens] Length = 898 Score = 62.8 bits (151), Expect = 5e-10 Identities = 73/275 (26%), Positives = 98/275 (35%), Gaps = 32/275 (11%) Query: 150 PGYSHAGPASQGVP----MQGQGTIGNYVSRTNINM--QSNPVSMMQQQAATSHY----- 198 PG+ GP VP ++G+G G+ R +N M A Y Sbjct: 625 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGN 684 Query: 199 SSAQGGSQHYQ--GQSSIAMMGQGS-------QGSSMMGQRPMAPYRPSQQGSSQQYLGQ 249 S+ G SQ Y G S A G G GS G +P P G Q + GQ Sbjct: 685 SATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQ 744 Query: 250 EE-YYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNS 308 ++ YG Y QG + Q Y + +G +Q Y S+ S GG S Sbjct: 745 QKPSYGSGYQSHQGQQQSYNQSPYSN-YGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGS 803 Query: 309 QYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGS 368 Y+ + G+ + + PG GYG G S Y G Q G Q + Sbjct: 804 DYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQ--SN 861 Query: 369 YRAPQTA------PSAQQ--QRPYGYEQGQYGNYQ 395 Y +P + PS+ Q Q YG NYQ Sbjct: 862 YNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQ 896 >gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo sapiens] Length = 894 Score = 62.8 bits (151), Expect = 5e-10 Identities = 73/275 (26%), Positives = 98/275 (35%), Gaps = 32/275 (11%) Query: 150 PGYSHAGPASQGVP----MQGQGTIGNYVSRTNINM--QSNPVSMMQQQAATSHY----- 198 PG+ GP VP ++G+G G+ R +N M A Y Sbjct: 621 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGN 680 Query: 199 SSAQGGSQHYQ--GQSSIAMMGQGS-------QGSSMMGQRPMAPYRPSQQGSSQQYLGQ 249 S+ G SQ Y G S A G G GS G +P P G Q + GQ Sbjct: 681 SATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQ 740 Query: 250 EE-YYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNS 308 ++ YG Y QG + Q Y + +G +Q Y S+ S GG S Sbjct: 741 QKPSYGSGYQSHQGQQQSYNQSPYSN-YGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGS 799 Query: 309 QYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGS 368 Y+ + G+ + + PG GYG G S Y G Q G Q + Sbjct: 800 DYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQ--SN 857 Query: 369 YRAPQTA------PSAQQ--QRPYGYEQGQYGNYQ 395 Y +P + PS+ Q Q YG NYQ Sbjct: 858 YNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQ 892 >gi|171916097 repetin [Homo sapiens] Length = 784 Score = 62.8 bits (151), Expect = 5e-10 Identities = 72/267 (26%), Positives = 108/267 (40%), Gaps = 44/267 (16%) Query: 156 GPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA--QGGSQHY----- 208 G +S M QG G++ +T+ QS+ +Q SHY QG S HY Sbjct: 410 GQSSHYSQMDRQGQ-GSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDR 468 Query: 209 QGQSSIAMM----GQGSQGSSMMGQRPMAPY-RPSQQGSSQQYLGQEEYYGEQYSHSQGA 263 QGQSS GQ S + Q Y +P QG S Y GQ + G+ + + Q Sbjct: 469 QGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHY-GQTDRQGQSFHYGQPD 527 Query: 264 AEPMGQQYYP-DGHGDYA-YQQSSYTEQS--YDRSFEESTQHYY-----EGGNSQYSQQQ 314 + Y D G + Y Q+ QS Y ++ + ++Y +G +S Y Q Q Sbjct: 528 RQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQ 587 Query: 315 AGYQQG---------AAQQQTYSQQ---------QYPSQQSYPGQQQGYGSAQGAPSQYP 356 G QG ++ +Y +Q Q P Q+ Y Q QG+ Q SQ Sbjct: 588 TGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGF---QSRDSQQN 644 Query: 357 GYQQGQGQQYGSYRAPQTAPSAQQQRP 383 G+Q + ++ + + QQ+RP Sbjct: 645 GHQVWEPEEDSQHHQHKLLAQIQQERP 671 Score = 53.9 bits (128), Expect = 2e-07 Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%) Query: 165 QGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA--QGGSQHY-----QGQSS---- 213 QGQG+ + S+ N QS+ Q +SHY Q S HY QGQSS Sbjct: 361 QGQGS---HYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQ 417 Query: 214 IAMMGQGSQGSSMMGQRPMAPY-RPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQY- 271 + GQGS Q + Y +P +QG + Y GQ + G+ + Q + Y Sbjct: 418 MDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHY-GQTDRQGQSSHYGQTDRQGQSSHYS 476 Query: 272 YPDGHGDYA-YQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQT--YS 328 PD G + Y + +QSY + G + Q Y Q Q Q+ YS Sbjct: 477 QPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYS 536 Query: 329 QQQYPSQQSYPGQ--QQG----YGSAQGAPSQYPGYQQGQGQQYG-SYRAPQTAPSAQQQ 381 Q Q S+ GQ +QG YG +QGQ YG + R Q++ Q Q Sbjct: 537 QMDRQGQSSHYGQTDRQGQSSHYGQTD---------RQGQSYHYGQTDRQGQSSHYIQSQ 587 Query: 382 RPYGYEQGQYGNYQ 395 G QGQ +Q Sbjct: 588 T--GEIQGQNKYFQ 599 Score = 47.8 bits (112), Expect = 2e-05 Identities = 60/212 (28%), Positives = 82/212 (38%), Gaps = 26/212 (12%) Query: 196 SHYSSA-QGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYG 254 SH++ Q S Y GQS G + GQ + Y + + + GQ + G Sbjct: 257 SHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQS--SHYGQTDRQDQSYHYGQTDRQG 314 Query: 255 EQYSHSQGAAEPMGQQY-YPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQ- 312 + +SQ + Y PD G Q S Y + Q +G S YSQ Sbjct: 315 QSSHYSQTDRQGQSSHYSQPDRQG----QSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQP 370 Query: 313 ----QQAGYQQGAAQQQT--YSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGY-QQGQGQQ 365 Q + Y Q Q Q+ Y Q Q S+ GQ + QG S Y +QGQG Sbjct: 371 NRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTE----RQGQSSHYSQMDRQGQGSH 426 Query: 366 YG-SYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 YG + R Q++ Q R QGQ +Y Q Sbjct: 427 YGQTDRQGQSSHYGQPDR-----QGQNSHYGQ 453 Score = 45.1 bits (105), Expect = 1e-04 Identities = 59/228 (25%), Positives = 87/228 (38%), Gaps = 27/228 (11%) Query: 166 GQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA--QGGSQHY-----QGQSS----I 214 GQG +Y +T+ QS +Q +SHYS QG S HY QGQSS Sbjct: 504 GQGQSSHY-GQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQT 562 Query: 215 AMMGQGSQGSSMMGQRPMAPYRPSQ----QGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQ 270 GQ Q + Y SQ QG ++ + G E Y G + + QQ Sbjct: 563 DRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQ 622 Query: 271 ------YYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQ 324 Y G G + Q ++ EE +QH+ +Q Q++ +G Q Sbjct: 623 TPGQEGYQNQGQGFQSRDSQQNGHQVWEP--EEDSQHHQHKLLAQIQQERPLCHKGRDWQ 680 Query: 325 QTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP 372 S+Q + +Q+ Q G G + A + G+Q + S P Sbjct: 681 SCSSEQGH--RQAQTRQSHGEGLSHWAEEE-QGHQTWDRHSHESQEGP 725 Score = 31.2 bits (69), Expect = 1.7 Identities = 35/168 (20%), Positives = 58/168 (34%), Gaps = 13/168 (7%) Query: 236 RPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSF 295 +P +Q + GQ E H Q + + D + Q D SF Sbjct: 136 QPERQDGDSHH-GQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSF 194 Query: 296 EESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQ--QYPSQQSYPGQQQGYGSAQGAPS 353 ++S + + + + ++ Q Q ++ + P Q S+ GQ + + Sbjct: 195 DQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLG 254 Query: 354 QYPGYQQGQGQQYGSY-----RAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 Q + Q Q+ GSY R Q Q R QGQ +Y Q Sbjct: 255 QASHFNQTNQQKSGSYCGQSERLGQELGCGQTDR-----QGQSSHYGQ 297 >gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] Length = 589 Score = 60.5 bits (145), Expect = 3e-09 Identities = 60/190 (31%), Positives = 80/190 (42%), Gaps = 24/190 (12%) Query: 196 SHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGE 255 S+ + GSQ Y GQ+S + G G S GQ + Y Q SQ Y G E + Sbjct: 16 SYSTYGNPGSQGY-GQASQSYSGYGQTTDSSYGQN-YSGYSSYGQSYSQSYGGYENQ--K 71 Query: 256 QYSHSQGAAEPMGQQYYPDGHG------------DYAYQQSSYTEQS-YDR---SFEEST 299 Q S+SQ GQQ + G DY QQ SY +QS YD+ S++E Sbjct: 72 QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG-QQDSYDQQSGYDQHQGSYDE-- 128 Query: 300 QHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGY- 358 Q Y+ + YSQ Q Y ++Q Y +GYG +QG GY Sbjct: 129 QSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYD 188 Query: 359 QQGQGQQYGS 368 + G+G GS Sbjct: 189 KDGRGPMTGS 198 Score = 52.8 bits (125), Expect = 5e-07 Identities = 45/145 (31%), Positives = 59/145 (40%), Gaps = 22/145 (15%) Query: 258 SHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNS---QYSQQQ 314 S+ Q E Y + G Y Q+S + Y ++ + S Y G +S YSQ Sbjct: 6 SYGQSGGEQQSYSTYGNP-GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64 Query: 315 AGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQT 374 GY+ +Q +YSQQ Y +Q GQQQ S+ + P Y Q Q SY Sbjct: 65 GGYEN--QKQSSYSQQPYNNQ----GQQQNMESSGSQGGRAPSYDQPDYGQQDSY----- 113 Query: 375 APSAQQQRPYGYEQGQY---GNYQQ 396 QQ Y QG Y NY Q Sbjct: 114 ----DQQSGYDQHQGSYDEQSNYDQ 134 Score = 52.0 bits (123), Expect = 9e-07 Identities = 53/194 (27%), Positives = 73/194 (37%), Gaps = 46/194 (23%) Query: 203 GGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQG 262 GG Q QS GSQG Q + + Q Y G YG+ YS S G Sbjct: 11 GGEQ----QSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS-YGQSYSQSYG 65 Query: 263 AAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA 322 E +QSSY++Q Y+ Q + + +G Q G A Sbjct: 66 GYENQ--------------KQSSYSQQPYNNQ------------GQQQNMESSGSQGGRA 99 Query: 323 QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQR 382 +Y Q Y Q SY QQ GY QG+ + Y QQ+ SY +Q Q+ Sbjct: 100 --PSYDQPDYGQQDSY-DQQSGYDQHQGSYDEQSNYD----QQHDSY--------SQNQQ 144 Query: 383 PYGYEQGQYGNYQQ 396 Y ++ Y ++ Q Sbjct: 145 SYHSQRENYSHHTQ 158 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 58.9 bits (141), Expect = 8e-09 Identities = 78/322 (24%), Positives = 111/322 (34%), Gaps = 30/322 (9%) Query: 76 PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQT 135 P+P GP +GS+ G L P + Q G S +S+ Sbjct: 1123 PSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQ-GGRSSTISVHDP 1181 Query: 136 APNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAAT 195 + +S + + P Q ++ + + R +P M++ + Sbjct: 1182 FSD--------VSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGS 1233 Query: 196 SHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGE 255 S QG + Q G+ + MGQR PY S Y + E YG+ Sbjct: 1234 SEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS-------YDRRHEPYGQ 1286 Query: 256 QYSHSQGAAEPMGQQYYPDGHGDYAY-QQSSYTEQSYDRSFEESTQHYYEGGNSQY-SQQ 313 QY G P GQ Y GH Y QQ +Y + +H + N QY SQQ Sbjct: 1287 QY---PGQGPPSGQPPY-GGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQ 1342 Query: 314 QAGYQQGAAQQQTYSQQQYPSQQSYP---GQQQGYGSAQ--GAPSQYPGYQQGQGQQYGS 368 Q Y Q ++ Q YP + QG G Q G P Q G G Q S Sbjct: 1343 QEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMG---GPLQSSSS 1399 Query: 369 YRAPQTAPSAQQQRPYGYEQGQ 390 Q +A+ PY Y+ Q Sbjct: 1400 EGPQQNMWAARNDMPYPYQNRQ 1421 Score = 42.4 bits (98), Expect = 7e-04 Identities = 61/228 (26%), Positives = 73/228 (32%), Gaps = 39/228 (17%) Query: 200 SAQGGSQHYQGQS---------------SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244 SA GG Q + GQ+ S + M + GS P AP P Q SQ Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398 Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQS-------------- 290 G+Q + G + MG QY A QQ S+ S Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458 Query: 291 -YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQ 349 D + Q Y G N QQ+ G + P Q YP QG Sbjct: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP-------PGPQRYPIGIQGRTPGA 511 Query: 350 GAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGY-EQGQYGNYQQ 396 A QYP QQ G P QQ GY +QGQ Y Q Sbjct: 512 MAGMQYP-QQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQ 558 Score = 42.0 bits (97), Expect = 0.001 Identities = 71/257 (27%), Positives = 95/257 (36%), Gaps = 60/257 (23%) Query: 171 GNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG-------------------- 210 G+Y ++ + P S Q QAA + +A GG Q G Sbjct: 377 GSYPEYSSPSAPPPPPSQPQSQAAAA--GAAAGGQQAAAGMGLGKDMGAQYAAASPAWAA 434 Query: 211 --QSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQY-LGQEEYYGEQYS--HSQGAAE 265 Q S M G+ G +M G+ +P P Q Y +G + Q S + G+ Sbjct: 435 AQQRSHPAMSPGTPGPTM-GRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493 Query: 266 PMGQQYYPDG-----HGDYAYQQSSYTEQSYDRSFEES----TQHYYEGGNSQYSQQQAG 316 P G Q YP G G A Q + S D +++E+ Y + G S Y QQ Sbjct: 494 PPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQ--- 550 Query: 317 YQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ-YGSYRAPQTA 375 QQ YSQQ P P Q Q Y +Q P QQ Q+ YG+ P A Sbjct: 551 -----GQQPYYSQQ--PQPPHLPPQAQ-YLPSQSQQRYQP--QQDMSQEGYGTRSQPPLA 600 Query: 376 PS---------AQQQRP 383 P QQ+RP Sbjct: 601 PGKPNHEDLNLIQQERP 617 Score = 36.2 bits (82), Expect = 0.053 Identities = 73/303 (24%), Positives = 110/303 (36%), Gaps = 49/303 (16%) Query: 74 LLPAPPT-QNMNL----GPGALTQ-SGSSQGLHS--QGSLSDAISTGLPPSSLLQGQIGN 125 L P P +++NL P +L SGS L + + +LS A+S SS QG Sbjct: 599 LAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS--QGD--- 653 Query: 126 GPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNI-NMQSN 184 S+ + +P+ P S GP P+ G P+ + +S +I Q Sbjct: 654 -QSNPAQSPFSPHASPHLSSIPGGPS-----PSPVGSPVGSNQSRSGPISPASIPGSQMP 707 Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSS- 243 P Q ++SH + +Q +G + G+Q + M Q Y P Q G S Sbjct: 708 PQPPGSQSESSSHPALSQSPMPQERGFMA------GTQRNPQMAQ-----YGPQQTGPSM 756 Query: 244 --------QQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDY--AYQ---QSSYTEQS 290 Q + G + Q S+S G P QY P G+ AY +SY+ Sbjct: 757 SPHPSPGGQMHAGISSF---QQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 813 Query: 291 YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA-QQQTYSQQQYPSQQSYPGQQQGYGSAQ 349 + Q + +G + G A Q + + S PG Q G Sbjct: 814 PGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 873 Query: 350 GAP 352 G P Sbjct: 874 GPP 876 Score = 34.3 bits (77), Expect = 0.20 Identities = 43/178 (24%), Positives = 59/178 (33%), Gaps = 22/178 (12%) Query: 224 SSMMGQRPMAPYRPSQQGSSQ-QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQ 282 SS + M P P QQG S +G+ Y + +P G G + Sbjct: 1188 SSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNK--------DPFGGMRKVPGSSEPFMT 1239 Query: 283 QSSYTEQSYDRSFEESTQHYYEGGNSQYSQ-QQAGYQQGAAQQQTYSQ--QQYPSQQSYP 339 Q S + +S G S Q+ + GA+ + + QQYP Q Sbjct: 1240 QGQMPNSSMQDMYNQSPS----GAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPS 1295 Query: 340 GQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391 GQ G G Q P Y++ YG S+QQQ Y G Y Sbjct: 1296 GQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSY 1353 Score = 33.1 bits (74), Expect = 0.45 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 6/83 (7%) Query: 281 YQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYP-SQQSYP 339 +QQ + ++ H++ Q +Q Q QQ QQQ QQQ+P S + Sbjct: 23 HQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL 82 Query: 340 GQQQGYGSAQGAPSQYPGYQQGQ 362 G G+ GAP P +Q Q Sbjct: 83 G-----GAGGGAPQPGPDMEQPQ 100 Score = 31.2 bits (69), Expect = 1.7 Identities = 82/364 (22%), Positives = 119/364 (32%), Gaps = 53/364 (14%) Query: 76 PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSD---------------------AISTGLP 114 P PP+Q + A +G Q G D A+S G P Sbjct: 389 PPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTP 448 Query: 115 PSSLLQGQIGNGPSHVSMQQ-------TAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQ 167 ++ + Q G+ + M++ + P++ P S G Y GP + +QG+ Sbjct: 449 GPTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGR 507 Query: 168 GTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMM 227 T G Q + + ++ T Q G Q G SQ Sbjct: 508 -TPGAMAGMQYPQQQDSGDATWKE---TFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPP 563 Query: 228 GQRPMAPYRPSQQGSSQQYLGQEEYYGEQY-SHSQGAAEPMGQQYYPDGHGDYAYQQSSY 286 P A Y PSQ S Q+Y Q++ E Y + SQ P G+ + D + + SS Sbjct: 564 HLPPQAQYLPSQ--SQQRYQPQQDMSQEGYGTRSQPPLAP-GKPNHEDLNLIQQERPSSL 620 Query: 287 TEQSYD-RSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPG--QQQ 343 + S T+ S + Q Q +S P S PG Sbjct: 621 PDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPS 680 Query: 344 GYGSAQG---------APSQYPGYQ---QGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391 GS G +P+ PG Q Q G Q S P + S Q G+ G Sbjct: 681 PVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQE-RGFMAGTQ 739 Query: 392 GNYQ 395 N Q Sbjct: 740 RNPQ 743 Score = 29.6 bits (65), Expect = 5.0 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 22/121 (18%) Query: 70 NMQSLLPAPPTQNMNLGPG-----------------ALTQSGSSQGLHSQGSLSDAISTG 112 NM S+ P+ P + GPG A+ Q+ ++ QGS +G Sbjct: 854 NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG 913 Query: 113 LPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQG-----VPMQGQ 167 L SS Q N S + Q P ++ ++ S A S G +P++ Sbjct: 914 LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 973 Query: 168 G 168 G Sbjct: 974 G 974 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 58.9 bits (141), Expect = 8e-09 Identities = 78/322 (24%), Positives = 111/322 (34%), Gaps = 30/322 (9%) Query: 76 PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQT 135 P+P GP +GS+ G L P + Q G S +S+ Sbjct: 1163 PSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQ-GGRSSTISVHDP 1221 Query: 136 APNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAAT 195 + +S + + P Q ++ + + R +P M++ + Sbjct: 1222 FSD--------VSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGS 1273 Query: 196 SHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGE 255 S QG + Q G+ + MGQR PY S Y + E YG+ Sbjct: 1274 SEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS-------YDRRHEPYGQ 1326 Query: 256 QYSHSQGAAEPMGQQYYPDGHGDYAY-QQSSYTEQSYDRSFEESTQHYYEGGNSQY-SQQ 313 QY G P GQ Y GH Y QQ +Y + +H + N QY SQQ Sbjct: 1327 QY---PGQGPPSGQPPY-GGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQ 1382 Query: 314 QAGYQQGAAQQQTYSQQQYPSQQSYP---GQQQGYGSAQ--GAPSQYPGYQQGQGQQYGS 368 Q Y Q ++ Q YP + QG G Q G P Q G G Q S Sbjct: 1383 QEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMG---GPLQSSSS 1439 Query: 369 YRAPQTAPSAQQQRPYGYEQGQ 390 Q +A+ PY Y+ Q Sbjct: 1440 EGPQQNMWAARNDMPYPYQNRQ 1461 Score = 42.7 bits (99), Expect = 6e-04 Identities = 59/221 (26%), Positives = 73/221 (33%), Gaps = 41/221 (18%) Query: 200 SAQGGSQHYQGQS---------------SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244 SA GG Q + GQ+ S + M + GS P AP P Q SQ Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398 Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQS-------------- 290 G+Q + G + MG QY A QQ S+ S Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458 Query: 291 -YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQ 349 D + Q Y G N QQ+ G + P Q YP QG Sbjct: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP-------PGPQRYPIGIQGRTPGA 511 Query: 350 GAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQ 390 A QYP QQ QYG + Q Q+PY +Q Q Sbjct: 512 MAGMQYP--QQQMPPQYGQQGV--SGYCQQGQQPYYSQQPQ 548 Score = 38.1 bits (87), Expect = 0.014 Identities = 68/251 (27%), Positives = 89/251 (35%), Gaps = 61/251 (24%) Query: 171 GNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG-------------------- 210 G+Y ++ + P S Q QAA + +A GG Q G Sbjct: 377 GSYPEYSSPSAPPPPPSQPQSQAAAA--GAAAGGQQAAAGMGLGKDMGAQYAAASPAWAA 434 Query: 211 --QSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQY-LGQEEYYGEQYS--HSQGAAE 265 Q S M G+ G +M G+ +P P Q Y +G + Q S + G+ Sbjct: 435 AQQRSHPAMSPGTPGPTM-GRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493 Query: 266 PMGQQYYP---DGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA 322 P G Q YP G A Y +Q + Y + G S Y QQ Sbjct: 494 PPGPQRYPIGIQGRTPGAMAGMQYPQQ-------QMPPQYGQQGVSGYCQQ--------G 538 Query: 323 QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ-YGSYRAPQTAPS---- 377 QQ YSQQ P P Q Q Y +Q P QQ Q+ YG+ P AP Sbjct: 539 QQPYYSQQ--PQPPHLPPQAQ-YLPSQSQQRYQP--QQDMSQEGYGTRSQPPLAPGKPNH 593 Query: 378 -----AQQQRP 383 QQ+RP Sbjct: 594 EDLNLIQQERP 604 Score = 36.2 bits (82), Expect = 0.053 Identities = 81/409 (19%), Positives = 126/409 (30%), Gaps = 101/409 (24%) Query: 76 PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSD---------------------AISTGLP 114 P PP+Q + A +G Q G D A+S G P Sbjct: 389 PPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTP 448 Query: 115 PSSLLQGQIGNGPSHVSMQQ-------TAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQ 167 ++ + Q G+ + M++ + P++ P S G Y GP + +QG+ Sbjct: 449 GPTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGR 507 Query: 168 GTIGNYVSRTNINMQSNP------VSMMQQQAATSHYSS--------------AQGGSQH 207 T G Q P VS QQ +YS Q Sbjct: 508 -TPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQR 566 Query: 208 YQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ--------------------------- 240 YQ Q ++ G G++ Q P+AP +P+ + Sbjct: 567 YQPQQDMSQEGYGTR-----SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGT 621 Query: 241 ----GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQY---YPDGHGDYAYQQSSYTEQSYDR 293 S+ G G+Q + +Q P + P G + QS Sbjct: 622 EATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSG 681 Query: 294 SFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPG------QQQGYGS 347 ++ SQ Q G Q ++ SQ P ++ + Q YG Sbjct: 682 PISPASI-----PGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGP 736 Query: 348 AQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 Q PS P G GQ + + Q + S+ P + G GNY + Sbjct: 737 QQTGPSMSPHPSPG-GQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSR 784 Score = 36.2 bits (82), Expect = 0.053 Identities = 73/303 (24%), Positives = 110/303 (36%), Gaps = 49/303 (16%) Query: 74 LLPAPPT-QNMNL----GPGALTQ-SGSSQGLHS--QGSLSDAISTGLPPSSLLQGQIGN 125 L P P +++NL P +L SGS L + + +LS A+S SS QG Sbjct: 586 LAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS--QGD--- 640 Query: 126 GPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNI-NMQSN 184 S+ + +P+ P S GP P+ G P+ + +S +I Q Sbjct: 641 -QSNPAQSPFSPHASPHLSSIPGGPS-----PSPVGSPVGSNQSRSGPISPASIPGSQMP 694 Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSS- 243 P Q ++SH + +Q +G + G+Q + M Q Y P Q G S Sbjct: 695 PQPPGSQSESSSHPALSQSPMPQERGFMA------GTQRNPQMAQ-----YGPQQTGPSM 743 Query: 244 --------QQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDY--AYQ---QSSYTEQS 290 Q + G + Q S+S G P QY P G+ AY +SY+ Sbjct: 744 SPHPSPGGQMHAGISSF---QQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 800 Query: 291 YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA-QQQTYSQQQYPSQQSYPGQQQGYGSAQ 349 + Q + +G + G A Q + + S PG Q G Sbjct: 801 PGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860 Query: 350 GAP 352 G P Sbjct: 861 GPP 863 Score = 34.3 bits (77), Expect = 0.20 Identities = 43/178 (24%), Positives = 59/178 (33%), Gaps = 22/178 (12%) Query: 224 SSMMGQRPMAPYRPSQQGSSQ-QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQ 282 SS + M P P QQG S +G+ Y + +P G G + Sbjct: 1228 SSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNK--------DPFGGMRKVPGSSEPFMT 1279 Query: 283 QSSYTEQSYDRSFEESTQHYYEGGNSQYSQ-QQAGYQQGAAQQQTYSQ--QQYPSQQSYP 339 Q S + +S G S Q+ + GA+ + + QQYP Q Sbjct: 1280 QGQMPNSSMQDMYNQSPS----GAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPS 1335 Query: 340 GQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391 GQ G G Q P Y++ YG S+QQQ Y G Y Sbjct: 1336 GQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSY 1393 Score = 33.1 bits (74), Expect = 0.45 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 6/83 (7%) Query: 281 YQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYP-SQQSYP 339 +QQ + ++ H++ Q +Q Q QQ QQQ QQQ+P S + Sbjct: 23 HQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL 82 Query: 340 GQQQGYGSAQGAPSQYPGYQQGQ 362 G G+ GAP P +Q Q Sbjct: 83 G-----GAGGGAPQPGPDMEQPQ 100 Score = 29.6 bits (65), Expect = 5.0 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 22/121 (18%) Query: 70 NMQSLLPAPPTQNMNLGPG-----------------ALTQSGSSQGLHSQGSLSDAISTG 112 NM S+ P+ P + GPG A+ Q+ ++ QGS +G Sbjct: 841 NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG 900 Query: 113 LPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQG-----VPMQGQ 167 L SS Q N S + Q P ++ ++ S A S G +P++ Sbjct: 901 LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960 Query: 168 G 168 G Sbjct: 961 G 961 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 58.9 bits (141), Expect = 8e-09 Identities = 78/322 (24%), Positives = 111/322 (34%), Gaps = 30/322 (9%) Query: 76 PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQT 135 P+P GP +GS+ G L P + Q G S +S+ Sbjct: 1110 PSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQ-GGRSSTISVHDP 1168 Query: 136 APNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAAT 195 + +S + + P Q ++ + + R +P M++ + Sbjct: 1169 FSD--------VSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGS 1220 Query: 196 SHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGE 255 S QG + Q G+ + MGQR PY S Y + E YG+ Sbjct: 1221 SEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS-------YDRRHEPYGQ 1273 Query: 256 QYSHSQGAAEPMGQQYYPDGHGDYAY-QQSSYTEQSYDRSFEESTQHYYEGGNSQY-SQQ 313 QY G P GQ Y GH Y QQ +Y + +H + N QY SQQ Sbjct: 1274 QY---PGQGPPSGQPPY-GGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQ 1329 Query: 314 QAGYQQGAAQQQTYSQQQYPSQQSYP---GQQQGYGSAQ--GAPSQYPGYQQGQGQQYGS 368 Q Y Q ++ Q YP + QG G Q G P Q G G Q S Sbjct: 1330 QEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMG---GPLQSSSS 1386 Query: 369 YRAPQTAPSAQQQRPYGYEQGQ 390 Q +A+ PY Y+ Q Sbjct: 1387 EGPQQNMWAARNDMPYPYQNRQ 1408 Score = 42.7 bits (99), Expect = 6e-04 Identities = 59/221 (26%), Positives = 73/221 (33%), Gaps = 41/221 (18%) Query: 200 SAQGGSQHYQGQS---------------SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244 SA GG Q + GQ+ S + M + GS P AP P Q SQ Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398 Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQS-------------- 290 G+Q + G + MG QY A QQ S+ S Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458 Query: 291 -YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQ 349 D + Q Y G N QQ+ G + P Q YP QG Sbjct: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP-------PGPQRYPIGIQGRTPGA 511 Query: 350 GAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQ 390 A QYP QQ QYG + Q Q+PY +Q Q Sbjct: 512 MAGMQYP--QQQMPPQYGQQGV--SGYCQQGQQPYYSQQPQ 548 Score = 38.1 bits (87), Expect = 0.014 Identities = 68/251 (27%), Positives = 89/251 (35%), Gaps = 61/251 (24%) Query: 171 GNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQG-------------------- 210 G+Y ++ + P S Q QAA + +A GG Q G Sbjct: 377 GSYPEYSSPSAPPPPPSQPQSQAAAA--GAAAGGQQAAAGMGLGKDMGAQYAAASPAWAA 434 Query: 211 --QSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQY-LGQEEYYGEQYS--HSQGAAE 265 Q S M G+ G +M G+ +P P Q Y +G + Q S + G+ Sbjct: 435 AQQRSHPAMSPGTPGPTM-GRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493 Query: 266 PMGQQYYP---DGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA 322 P G Q YP G A Y +Q + Y + G S Y QQ Sbjct: 494 PPGPQRYPIGIQGRTPGAMAGMQYPQQ-------QMPPQYGQQGVSGYCQQ--------G 538 Query: 323 QQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ-YGSYRAPQTAPS---- 377 QQ YSQQ P P Q Q Y +Q P QQ Q+ YG+ P AP Sbjct: 539 QQPYYSQQ--PQPPHLPPQAQ-YLPSQSQQRYQP--QQDMSQEGYGTRSQPPLAPGKPNH 593 Query: 378 -----AQQQRP 383 QQ+RP Sbjct: 594 EDLNLIQQERP 604 Score = 36.2 bits (82), Expect = 0.053 Identities = 81/409 (19%), Positives = 126/409 (30%), Gaps = 101/409 (24%) Query: 76 PAPPTQNMNLGPGALTQSGSSQGLHSQGSLSD---------------------AISTGLP 114 P PP+Q + A +G Q G D A+S G P Sbjct: 389 PPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTP 448 Query: 115 PSSLLQGQIGNGPSHVSMQQ-------TAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQ 167 ++ + Q G+ + M++ + P++ P S G Y GP + +QG+ Sbjct: 449 GPTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGR 507 Query: 168 GTIGNYVSRTNINMQSNP------VSMMQQQAATSHYSS--------------AQGGSQH 207 T G Q P VS QQ +YS Q Sbjct: 508 -TPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQR 566 Query: 208 YQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ--------------------------- 240 YQ Q ++ G G++ Q P+AP +P+ + Sbjct: 567 YQPQQDMSQEGYGTR-----SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGT 621 Query: 241 ----GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQY---YPDGHGDYAYQQSSYTEQSYDR 293 S+ G G+Q + +Q P + P G + QS Sbjct: 622 EATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSG 681 Query: 294 SFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPG------QQQGYGS 347 ++ SQ Q G Q ++ SQ P ++ + Q YG Sbjct: 682 PISPASI-----PGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGP 736 Query: 348 AQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 Q PS P G GQ + + Q + S+ P + G GNY + Sbjct: 737 QQTGPSMSPHPSPG-GQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSR 784 Score = 36.2 bits (82), Expect = 0.053 Identities = 73/303 (24%), Positives = 110/303 (36%), Gaps = 49/303 (16%) Query: 74 LLPAPPT-QNMNL----GPGALTQ-SGSSQGLHS--QGSLSDAISTGLPPSSLLQGQIGN 125 L P P +++NL P +L SGS L + + +LS A+S SS QG Sbjct: 586 LAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS--QGD--- 640 Query: 126 GPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNI-NMQSN 184 S+ + +P+ P S GP P+ G P+ + +S +I Q Sbjct: 641 -QSNPAQSPFSPHASPHLSSIPGGPS-----PSPVGSPVGSNQSRSGPISPASIPGSQMP 694 Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSS- 243 P Q ++SH + +Q +G + G+Q + M Q Y P Q G S Sbjct: 695 PQPPGSQSESSSHPALSQSPMPQERGFMA------GTQRNPQMAQ-----YGPQQTGPSM 743 Query: 244 --------QQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDY--AYQ---QSSYTEQS 290 Q + G + Q S+S G P QY P G+ AY +SY+ Sbjct: 744 SPHPSPGGQMHAGISSF---QQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 800 Query: 291 YDRSFEESTQHYYEGGNSQYSQQQAGYQQGAA-QQQTYSQQQYPSQQSYPGQQQGYGSAQ 349 + Q + +G + G A Q + + S PG Q G Sbjct: 801 PGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860 Query: 350 GAP 352 G P Sbjct: 861 GPP 863 Score = 34.3 bits (77), Expect = 0.20 Identities = 43/178 (24%), Positives = 59/178 (33%), Gaps = 22/178 (12%) Query: 224 SSMMGQRPMAPYRPSQQGSSQ-QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQ 282 SS + M P P QQG S +G+ Y + +P G G + Sbjct: 1175 SSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNK--------DPFGGMRKVPGSSEPFMT 1226 Query: 283 QSSYTEQSYDRSFEESTQHYYEGGNSQYSQ-QQAGYQQGAAQQQTYSQ--QQYPSQQSYP 339 Q S + +S G S Q+ + GA+ + + QQYP Q Sbjct: 1227 QGQMPNSSMQDMYNQSPS----GAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPS 1282 Query: 340 GQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391 GQ G G Q P Y++ YG S+QQQ Y G Y Sbjct: 1283 GQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSY 1340 Score = 33.1 bits (74), Expect = 0.45 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 6/83 (7%) Query: 281 YQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYP-SQQSYP 339 +QQ + ++ H++ Q +Q Q QQ QQQ QQQ+P S + Sbjct: 23 HQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL 82 Query: 340 GQQQGYGSAQGAPSQYPGYQQGQ 362 G G+ GAP P +Q Q Sbjct: 83 G-----GAGGGAPQPGPDMEQPQ 100 Score = 29.6 bits (65), Expect = 5.0 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 22/121 (18%) Query: 70 NMQSLLPAPPTQNMNLGPG-----------------ALTQSGSSQGLHSQGSLSDAISTG 112 NM S+ P+ P + GPG A+ Q+ ++ QGS +G Sbjct: 841 NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG 900 Query: 113 LPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQG-----VPMQGQ 167 L SS Q N S + Q P ++ ++ S A S G +P++ Sbjct: 901 LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960 Query: 168 G 168 G Sbjct: 961 G 961 >gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo sapiens] Length = 600 Score = 54.7 bits (130), Expect = 1e-07 Identities = 53/215 (24%), Positives = 76/215 (35%), Gaps = 12/215 (5%) Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240 M S S Q AA YS+ +Q QG + G Q GQ Y +Q Sbjct: 1 MASTDYSTYSQAAAQQGYSAYT--AQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQT 57 Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 ++ YG+ + P G+G AY ++ T + S+ + Sbjct: 58 TATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSA 117 Query: 301 HYYEGGNSQYSQQQAGY---QQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357 + + Y QQ A + Q +Y Q Y Q +Y G S+ G S Y G Sbjct: 118 YGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTY-----GQPSSYGQQSSY-G 171 Query: 358 YQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYG 392 Q GQQ + PQT +Q Y + YG Sbjct: 172 QQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYG 206 Score = 42.0 bits (97), Expect = 0.001 Identities = 59/258 (22%), Positives = 88/258 (34%), Gaps = 21/258 (8%) Query: 142 TTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA 201 T S + + GYS A P QG + + P + QA T+ A Sbjct: 8 TYSQAAAQQGYS----AYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTT----A 59 Query: 202 QGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLG--QEEYYGEQYSH 259 G Y G + + +P+ Y ++ + Q Y + Sbjct: 60 TYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG 119 Query: 260 SQGAAEPMGQQYYPDGHGDYAYQQ-SSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQ 318 +Q A GQQ Y+ Q +SY + SY + Y G S Y QQ + Q Sbjct: 120 TQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSY-GQQSSYGQQSSYGQ 178 Query: 319 QGAAQ--QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP---- 372 Q QT S Q PSQ Y Q YG +P GQ+ G + P Sbjct: 179 QPPTSYPPQTGSYSQAPSQ--YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENR 236 Query: 373 -QTAPSAQQQRPYGYEQG 389 + P + + G+++G Sbjct: 237 SMSGPDNRGRGRGGFDRG 254 >gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo sapiens] Length = 661 Score = 54.7 bits (130), Expect = 1e-07 Identities = 87/327 (26%), Positives = 116/327 (35%), Gaps = 54/327 (16%) Query: 69 QNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPS 128 Q S A PTQ G TQ+ Q + G +D +S ++ GQ S Sbjct: 15 QQGYSAYTAQPTQ----GYAQTTQAYGQQSYGTYGQPTD-VSYTQAQTTATYGQTAYATS 69 Query: 129 HVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSM 188 + P T+ TS + P P + P+QG GT G Y + T + + Sbjct: 70 YGQ-----PPTVEGTSTGYTTP----TAPQAYSQPVQGYGT-GAYDTTT-----ATVTTT 114 Query: 189 MQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLG 248 AA S Y + A G Q ++ RP +P++ Q G Sbjct: 115 QASYAAQSAYGTQP------------AYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTG 162 Query: 249 QEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNS 308 Y S + YP G Y Q + S+ + Y+ S Sbjct: 163 GYNQPSLGYGQSNYS--------YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYD--QS 212 Query: 309 QYSQQQA-GYQQGAAQQQTYSQQQYPSQQ---SYPGQQQGYGSAQGAPSQYPGYQQGQGQ 364 YSQQ G QQ +Y QQ QQ SYP Q GS APSQY GQ Sbjct: 213 SYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQT---GSYSQAPSQYSQQSSSYGQ 269 Query: 365 QYGSYRAPQTAPSAQQQRPYGYEQGQY 391 Q S+R Q PS+ YG E G + Sbjct: 270 Q-SSFR--QDHPSS--MGVYGQESGGF 291 Score = 35.0 bits (79), Expect = 0.12 Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 14/114 (12%) Query: 278 DYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQS 337 DY+ + +Q Y + TQ Y + Y QQ G G +Y+Q Q + Sbjct: 5 DYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYG-TYGQPTDVSYTQAQTTATYG 62 Query: 338 YPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391 Q Y ++ G P G G Y P TAP A Q GY G Y Sbjct: 63 ----QTAYATSYGQPPTVEGTSTG-------YTTP-TAPQAYSQPVQGYGTGAY 104 Score = 32.7 bits (73), Expect = 0.59 Identities = 39/170 (22%), Positives = 53/170 (31%), Gaps = 37/170 (21%) Query: 258 SHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGY 317 ++SQ AA+ Y YA +Y +QSY ++ + T Y + + Q Y Sbjct: 8 TYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYG-TYGQPTDVSYTQAQTTATYGQTAY 66 Query: 318 QQGAAQQQT-------YSQQQYPSQQSYPGQQQGYG-------------------SAQGA 351 Q T Y+ P S P Q G G SA G Sbjct: 67 ATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 126 Query: 352 PSQYPGYQQ----------GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391 YP Y Q G + PQ++ Q GY Q Y Sbjct: 127 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNY 176 >gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma) [Homo sapiens] Length = 526 Score = 54.7 bits (130), Expect = 1e-07 Identities = 53/156 (33%), Positives = 61/156 (39%), Gaps = 27/156 (17%) Query: 253 YGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSS--YTEQSYDRSFEESTQHYYEGGNSQY 310 Y +Q + S GA YP G QQSS Y +QSY + + Y G S Y Sbjct: 6 YTQQATQSYGA--------YPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY--GQSSY 55 Query: 311 SQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ---------- 360 S G Q T Q Y S Y G Q S+ G S YPGY Q Sbjct: 56 SSYGQSQNTGYGTQST--PQGYGSTGGY-GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGS 112 Query: 361 -GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQ 395 G Q SY PQ+ S QQ YG +Q YG Q Sbjct: 113 YGSSSQSSSYGQPQSG-SYSQQPSYGGQQQSYGQQQ 147 Score = 53.9 bits (128), Expect = 2e-07 Identities = 70/255 (27%), Positives = 84/255 (32%), Gaps = 49/255 (19%) Query: 122 QIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINM 181 Q G G S S Q + S S GY + +S G Q Q T Sbjct: 20 QPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYG---QSQNT--------GYGT 68 Query: 182 QSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMG----QRPMAPYRP 237 QS P Q +T Y S+Q Y QSS GQ SS G + Y Sbjct: 69 QSTP----QGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQ 124 Query: 238 SQQGSSQQ---YLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRS 294 Q GS Q Y GQ++ YG+Q S++ P G+G QQ+ Y S Sbjct: 125 PQSGSYSQQPSYGGQQQSYGQQQSYNP-----------PQGYG----QQNQYNSSSGGGG 169 Query: 295 FEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQ 354 GG Y Q Q+ G Y Q QS G GYG Sbjct: 170 --------GGGGGGNYGQDQSSMSSGGGSGGGYGNQ----DQSGGGGSGGYGQQDRGGRG 217 Query: 355 YPGYQQGQGQQYGSY 369 G G G G Y Sbjct: 218 RGGSGGGGGGGGGGY 232 Score = 53.9 bits (128), Expect = 2e-07 Identities = 62/200 (31%), Positives = 74/200 (37%), Gaps = 19/200 (9%) Query: 196 SHYSSAQGGSQHYQGQS-SIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYG 254 S SS G Q Y G S S G G S GQ Y Q + Q Y G YG Sbjct: 26 SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGY--GTQSTPQGY-GSTGGYG 82 Query: 255 EQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQ 314 SQ + GQQ G+G S T SY S + S+ Y + + YSQQ Sbjct: 83 S----SQSSQSSYGQQSSYPGYGQQPAPSS--TSGSYGSSSQSSS--YGQPQSGSYSQQP 134 Query: 315 A--GYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP 372 + G QQ QQQ+Y+ Q QQ+ G G G Y GQ Q S Sbjct: 135 SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY-----GQDQSSMSSGGG 189 Query: 373 QTAPSAQQQRPYGYEQGQYG 392 Q + G G YG Sbjct: 190 SGGGYGNQDQSGGGGSGGYG 209 Score = 51.6 bits (122), Expect = 1e-06 Identities = 52/166 (31%), Positives = 68/166 (40%), Gaps = 22/166 (13%) Query: 240 QGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEEST 299 Q ++Q Y G+ YS Q +++P GQQ Y Y QS+ T S+ Sbjct: 8 QQATQSYGAYPTQPGQGYS--QQSSQPYGQQSYS------GYSQSTDTSGYGQSSYSSYG 59 Query: 300 QHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQ---------GYGSAQG 350 Q G +Q + Q G G Q+ SQ Y Q SYPG Q YGS+ Sbjct: 60 QSQNTGYGTQSTPQGYGSTGGYGSSQS-SQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQ 118 Query: 351 APSQYPGYQQGQGQQYGSYRAPQTAPSAQQ--QRPYGY-EQGQYGN 393 + S Y Q G Q SY Q + QQ P GY +Q QY + Sbjct: 119 S-SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNS 163 Score = 39.3 bits (90), Expect = 0.006 Identities = 34/96 (35%), Positives = 38/96 (39%), Gaps = 13/96 (13%) Query: 313 QQAGYQQGAAQQQT---YSQQ--QYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYG 367 QQA GA Q YSQQ Q QQSY G Q ++ S Y Y Q Q YG Sbjct: 8 QQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYG 67 Query: 368 SYRAPQ-------TAPSAQQQRPYGYEQGQYGNYQQ 396 + PQ S Q YG +Q Y Y Q Sbjct: 68 TQSTPQGYGSTGGYGSSQSSQSSYG-QQSSYPGYGQ 102 >gi|93141033 PAX interacting protein 1 [Homo sapiens] Length = 1069 Score = 54.3 bits (129), Expect = 2e-07 Identities = 79/316 (25%), Positives = 111/316 (35%), Gaps = 23/316 (7%) Query: 78 PPTQNMNLGP---GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQ 134 PP L P G L +G Q L S S+ I+T P L+ N Q Sbjct: 297 PPVPGNILPPEVRGNLMAAG--QNLQSS-ERSEMIATWSPAVRTLRNITNNADIQ---QM 350 Query: 135 TAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQG-TIGNYVSRTNINMQSNPVSMMQQQA 193 P+ + ++S P + Q V QG T N V + + + P + M QQ Sbjct: 351 NRPSNVAHILQTLSAPTKN----LEQQVNHSQQGHTNANAVLFSQVKV--TPETHMLQQQ 404 Query: 194 ATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYY 253 + Q H Q Q + + Q Q S P+ SQQ QQ ++ Sbjct: 405 QQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFS 464 Query: 254 GEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQ 313 +Q Q P Q + P QQ + +Q + + Q Q+S Sbjct: 465 QQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLL 524 Query: 314 QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGS--AQGAPSQYPGYQQGQGQQYGSYRA 371 Q QQ QQQ Q QQ Q + S +Q Q P Q Q QQ Sbjct: 525 QQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQ-----Q 579 Query: 372 PQTAPSAQQQRPYGYE 387 Q PS QQ + +G++ Sbjct: 580 QQPPPSPQQHQLFGHD 595 Score = 40.8 bits (94), Expect = 0.002 Identities = 43/162 (26%), Positives = 60/162 (37%), Gaps = 7/162 (4%) Query: 238 SQQGSSQQ---YLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRS 294 SQQG + Q + E + Q QQ +P H Q + + Sbjct: 377 SQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLH----LQPQQIMQLQQQQQ 432 Query: 295 FEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQ 354 + S Q Y + +SQQQ QQ Q + Q Q+P QQ +P QQ Q P Q Sbjct: 433 QQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQ 492 Query: 355 YPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 Q Q Q ++ Q + QQ+ +Q Q QQ Sbjct: 493 QQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQ 534 >gi|31652242 transcription factor 20 isoform 2 [Homo sapiens] Length = 1938 Score = 54.3 bits (129), Expect = 2e-07 Identities = 86/343 (25%), Positives = 116/343 (33%), Gaps = 64/343 (18%) Query: 81 QNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTL 140 QN G+ SGS G +G+ + A + S QG G A N Sbjct: 39 QNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGH-QGYQGFRKEAGDFYYMAGNKD 97 Query: 141 PTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSS 200 P T+ + P +GP P QG Y S ++ S + SHY Sbjct: 98 PVTTGTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGL---GGVSHYQQ 154 Query: 201 ------AQGGSQHYQGQSSIAMMGQGSQGSSMMGQR----PMAPYRPSQQGSSQQYL--- 247 + G +Q+ Q SS Q Q + Q P A +P+ S Q + Sbjct: 155 DYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRP 214 Query: 248 --------GQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEEST 299 G + G+ H Q +A +P Q+ S + QSYD S+ + Sbjct: 215 STLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSP------QRFSQSGQSYDGSYNVNA 268 Query: 300 QHYYEGGN-----------SQYSQQ--------QAGYQQGAAQQQTYSQQQYPSQQSYPG 340 YEG N S YS Q QA QG Q Q QQQ P QQ +P Sbjct: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQ---QQQQPQQQQHPS 325 Query: 341 Q--QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQ 381 Q Q +A P Q Q G Y P+ + Q Sbjct: 326 QHVMQYTNAATKLPLQ---------SQVGQYNQPEVPVRSPMQ 359 Score = 43.5 bits (101), Expect = 3e-04 Identities = 54/205 (26%), Positives = 74/205 (36%), Gaps = 33/205 (16%) Query: 193 AATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEY 252 AA + +S G Q YQG + M G + P G+ Q + Sbjct: 64 AAAAAMASETSGHQGYQG-----FRKEAGDFYYMAGNKD-----PVTTGTPQPPQRRPSG 113 Query: 253 YGEQYSHSQGAAEPMGQQYYPDGH-GDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYS 311 + Y QG++ G QY +GH G + Q S S HY + +S Sbjct: 114 PVQSYGPPQGSS--FGNQYGSEGHVGQFQAQHSGLGGVS----------HYQQDYTGPFS 161 Query: 312 QQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRA 371 A YQQ A+ QQ Q Q QQ Y Q A G P+ + Q + Sbjct: 162 PGSAQYQQQASSQQQQQQVQQLRQQLYQSHQP-LPQATGQPASSSSHLQ-------PMQR 213 Query: 372 PQTAPSAQQQRPYGYEQGQYGNYQQ 396 P T PS+ Y GQ+G + Q Sbjct: 214 PSTLPSS--AAGYQLRVGQFGQHYQ 236 Score = 35.4 bits (80), Expect = 0.091 Identities = 56/290 (19%), Positives = 104/290 (35%), Gaps = 46/290 (15%) Query: 63 TIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQ 122 T ++ + + L +P ++++ G + S QG + + S+ + Sbjct: 499 TNSEGSSQPEEQLKSPMAESLD---GGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEK 555 Query: 123 IGNGPSHVSMQQTAP-NTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNI-- 179 G+ P+ + + N P + PG +S G P + T+G VSR + Sbjct: 556 AGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTG 615 Query: 180 -----------NMQSNPVSMMQQQA-----ATSHYSSAQ---------GGSQHYQGQSSI 214 + + +P + + + TSH S Q G+++ S+ Sbjct: 616 RVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNH 675 Query: 215 AMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEP---MGQQY 271 G G G S G + PS+ S +Y Y S G+A P G Sbjct: 676 NGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRY---------SYKDSFGSAVPRNVSGFPQ 726 Query: 272 YPDGH--GDY-AYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQ 318 YP G GD+ + + + + +E Q Y+ + +YS+ +Q Sbjct: 727 YPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQ 776 >gi|31652244 transcription factor 20 isoform 1 [Homo sapiens] Length = 1960 Score = 54.3 bits (129), Expect = 2e-07 Identities = 86/343 (25%), Positives = 116/343 (33%), Gaps = 64/343 (18%) Query: 81 QNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTL 140 QN G+ SGS G +G+ + A + S QG G A N Sbjct: 39 QNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGH-QGYQGFRKEAGDFYYMAGNKD 97 Query: 141 PTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSS 200 P T+ + P +GP P QG Y S ++ S + SHY Sbjct: 98 PVTTGTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGL---GGVSHYQQ 154 Query: 201 ------AQGGSQHYQGQSSIAMMGQGSQGSSMMGQR----PMAPYRPSQQGSSQQYL--- 247 + G +Q+ Q SS Q Q + Q P A +P+ S Q + Sbjct: 155 DYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRP 214 Query: 248 --------GQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEEST 299 G + G+ H Q +A +P Q+ S + QSYD S+ + Sbjct: 215 STLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSP------QRFSQSGQSYDGSYNVNA 268 Query: 300 QHYYEGGN-----------SQYSQQ--------QAGYQQGAAQQQTYSQQQYPSQQSYPG 340 YEG N S YS Q QA QG Q Q QQQ P QQ +P Sbjct: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQ---QQQQPQQQQHPS 325 Query: 341 Q--QQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQ 381 Q Q +A P Q Q G Y P+ + Q Sbjct: 326 QHVMQYTNAATKLPLQ---------SQVGQYNQPEVPVRSPMQ 359 Score = 43.5 bits (101), Expect = 3e-04 Identities = 54/205 (26%), Positives = 74/205 (36%), Gaps = 33/205 (16%) Query: 193 AATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEY 252 AA + +S G Q YQG + M G + P G+ Q + Sbjct: 64 AAAAAMASETSGHQGYQG-----FRKEAGDFYYMAGNKD-----PVTTGTPQPPQRRPSG 113 Query: 253 YGEQYSHSQGAAEPMGQQYYPDGH-GDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYS 311 + Y QG++ G QY +GH G + Q S S HY + +S Sbjct: 114 PVQSYGPPQGSS--FGNQYGSEGHVGQFQAQHSGLGGVS----------HYQQDYTGPFS 161 Query: 312 QQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRA 371 A YQQ A+ QQ Q Q QQ Y Q A G P+ + Q + Sbjct: 162 PGSAQYQQQASSQQQQQQVQQLRQQLYQSHQP-LPQATGQPASSSSHLQ-------PMQR 213 Query: 372 PQTAPSAQQQRPYGYEQGQYGNYQQ 396 P T PS+ Y GQ+G + Q Sbjct: 214 PSTLPSS--AAGYQLRVGQFGQHYQ 236 Score = 35.4 bits (80), Expect = 0.091 Identities = 56/290 (19%), Positives = 104/290 (35%), Gaps = 46/290 (15%) Query: 63 TIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQ 122 T ++ + + L +P ++++ G + S QG + + S+ + Sbjct: 499 TNSEGSSQPEEQLKSPMAESLD---GGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEK 555 Query: 123 IGNGPSHVSMQQTAP-NTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNI-- 179 G+ P+ + + N P + PG +S G P + T+G VSR + Sbjct: 556 AGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTG 615 Query: 180 -----------NMQSNPVSMMQQQA-----ATSHYSSAQ---------GGSQHYQGQSSI 214 + + +P + + + TSH S Q G+++ S+ Sbjct: 616 RVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNH 675 Query: 215 AMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEP---MGQQY 271 G G G S G + PS+ S +Y Y S G+A P G Sbjct: 676 NGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRY---------SYKDSFGSAVPRNVSGFPQ 726 Query: 272 YPDGH--GDY-AYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQ 318 YP G GD+ + + + + +E Q Y+ + +YS+ +Q Sbjct: 727 YPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQ 776 >gi|60097902 filaggrin [Homo sapiens] Length = 4061 Score = 53.5 bits (127), Expect = 3e-07 Identities = 74/304 (24%), Positives = 116/304 (38%), Gaps = 34/304 (11%) Query: 86 GPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSM 145 G G +S G H ++ S G SS Q + G H S Q + + S Sbjct: 3587 GHGHSAESSRQSGTHH----AENSSGGQAASSHEQARSSAGERHGSHHQQSAD-----SS 3637 Query: 146 SISGPGYSHAGPASQGVPMQG-QGTIGNYVSRTNINMQSNPVSMMQQQAAT-----SHYS 199 SG G+ G AS V G +G+ G+ S + + + + + SH Sbjct: 3638 RHSGIGH---GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQE 3694 Query: 200 SAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSH 259 S +G S G+S + + S P +QGS + + Sbjct: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHE---------QARDS 3745 Query: 260 SQGAAEPMGQQYYPDGHGDY-AYQQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAG 316 S+ +A GQ G +Q SY EQS DRS + H + G S S Q+G Sbjct: 3746 SRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSG 3805 Query: 317 YQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAP 376 + +A ++T +++Q + G + S Q S++ Q GQG+ GS R+ + Sbjct: 3806 SR--SASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHS--QSGQGESAGSRRSRRQGS 3861 Query: 377 SAQQ 380 S Q Sbjct: 3862 SVSQ 3865 Score = 51.2 bits (121), Expect = 2e-06 Identities = 73/304 (24%), Positives = 116/304 (38%), Gaps = 34/304 (11%) Query: 88 GALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSI 147 G S G H +++ S G SS Q + G H S Q + + S Sbjct: 1320 GHSADSSRQSGTHH----TESSSHGQAVSSHEQARSSPGERHGSRHQQSAD-----SSRH 1370 Query: 148 SGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAAT-----SHYSSAQ 202 SG G+ A A + +G G+ V+ + + + + + SH SA+ Sbjct: 1371 SGIGHRQASSAVRDSGHRGSS--GSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESAR 1428 Query: 203 GGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQG 262 G S G+S + S S AP +QGS ++ ++S SQ Sbjct: 1429 GQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRH----EQARNSSRHSASQD 1484 Query: 263 AAEPMGQQYYPDGH--GDYAYQQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGYQ 318 + + GH +Q SY EQS DRS H + G S S Q+G + Sbjct: 1485 GQDTI------RGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPR 1538 Query: 319 QGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSA 378 +A +QT +++Q + G + S + S++ Q GQG+ GS + + S Sbjct: 1539 --SASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHS--QVGQGESAGSKTSRRQGSSV 1594 Query: 379 QQQR 382 Q R Sbjct: 1595 SQDR 1598 Score = 48.9 bits (115), Expect = 8e-06 Identities = 73/286 (25%), Positives = 111/286 (38%), Gaps = 33/286 (11%) Query: 106 SDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQ 165 +++ S G SS Q + G H S Q S SG G+ G AS V Sbjct: 1982 TESSSRGQAASSHEQARSSAGERHGSHHQLQS----ADSSRHSGIGH---GQASSAVRDS 2034 Query: 166 G-QGTIGNYVSRTNINMQSNPVSMMQQQAAT-----SHYSSAQGGSQHYQGQSS--IAMM 217 G +G G+ S + + + + + Q SH SA+G S G+S + + Sbjct: 2035 GHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQV 2094 Query: 218 GQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHG 277 Q S GQ AP +QGS +Y + S+ +A GQ G Sbjct: 2095 STHEQSESTHGQS--APSTGGRQGS---------HYDQAQDSSRHSASQEGQDTIRGHPG 2143 Query: 278 -DYAYQQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGYQQGAAQQQTYSQQQYPS 334 +Q S+ EQS DRS + H + G S S+ Q+G + +A ++TY ++Q Sbjct: 2144 PSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR--SASRKTYDKEQSGD 2201 Query: 335 QQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380 + G S+ S++ GQGQ G + S Q Sbjct: 2202 GSRHSGSHHHEASSWADSSRHS--LVGQGQSSGPRTSRPRGSSVSQ 2245 Score = 46.6 bits (109), Expect = 4e-05 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 19/201 (9%) Query: 184 NPVSMMQQQAATSHY--SSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPS--- 238 +P S + +A H SS Q G++H Q S Q S G+R + ++ S Sbjct: 2605 HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2664 Query: 239 ---------QQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQ 289 Q S+ + G Y G Q S ++G +E Q HG Q S+ E Sbjct: 2665 SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV-SAHGQAGSHQQSHQES 2723 Query: 290 SYDRSFE---ESTQHYYEGGNSQYSQQQAGYQQGAAQ-QQTYSQQQYPSQQSYPGQQQGY 345 + RS E S Y+ + S+ G+ + + +Q +Q + Q G Sbjct: 2724 ARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQ 2783 Query: 346 GSAQGAPSQYPGYQQGQGQQY 366 + +G P G +QG ++ Sbjct: 2784 DTIRGHPGSSRGGRQGYHHEH 2804 Score = 46.2 bits (108), Expect = 5e-05 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 19/201 (9%) Query: 184 NPVSMMQQQAATSHY--SSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPS--- 238 +P S + +A H SS Q G++H Q S Q S G+R + ++ S Sbjct: 2929 HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2988 Query: 239 ---------QQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQ 289 Q S+ + G Y G Q S ++G +E Q HG Q S+ E Sbjct: 2989 SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV-SAHGQAGSHQQSHQES 3047 Query: 290 SYDRSFE---ESTQHYYEGGNSQYSQQQAGYQQGAAQ-QQTYSQQQYPSQQSYPGQQQGY 345 + RS E S Y+ + S+ G+ + + +Q +Q + Q G Sbjct: 3048 ARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQ 3107 Query: 346 GSAQGAPSQYPGYQQGQGQQY 366 + +G P G +QG ++ Sbjct: 3108 DTIRGHPGSSRGGRQGYHHEH 3128 Score = 46.2 bits (108), Expect = 5e-05 Identities = 69/322 (21%), Positives = 109/322 (33%), Gaps = 28/322 (8%) Query: 91 TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGP 150 T++ G S+ S S S Q G G S + +T+ N + S Sbjct: 3489 TRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQS--AGPRTSRNQGSSVSQDSDSQ 3546 Query: 151 GYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHY--SSAQGGSQHY 208 G+S G + SR +P S + +A H SS Q G+ H Sbjct: 3547 GHSEDSERWSGSASRNHRGSAQEQSRDG---SRHPTSHHEDRAGHGHSAESSRQSGTHHA 3603 Query: 209 QGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYY------------GEQ 256 + S Q S G+R + ++ S S +G + G Q Sbjct: 3604 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQ 3663 Query: 257 YSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQH---YYEGGNSQYSQQ 313 S S+G +E Q HG Q S+ E + RS S + Y+ + S+ Sbjct: 3664 ASDSEGHSEDSDTQSV-SAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSES 3722 Query: 314 ---QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYR 370 +AG G Q + Q + S+ S Q+G + +G P G +QG + R Sbjct: 3723 AHGRAGPSTGGRQGSRHEQARDSSRHS--ASQEGQDTIRGHPGSRRGGRQGSYHEQSVDR 3780 Query: 371 APQTAPSAQQQRPYGYEQGQYG 392 + + G +G Sbjct: 3781 SGHSGSHHSHTTSQGRSDASHG 3802 Score = 44.7 bits (104), Expect = 1e-04 Identities = 68/292 (23%), Positives = 108/292 (36%), Gaps = 31/292 (10%) Query: 95 SSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSH 154 S G GS S+ S Q+G G S S +T+ N + S G+S Sbjct: 1874 SGDGSRHSGSRHHEASSRADSSR--HSQVGQGQS--SGPRTSRNQGSSVSQDSDSQGHSE 1929 Query: 155 AGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHY--SSAQGGSQHYQGQS 212 G + +G+ ++ + +P S + +A H SS Q G++H + S Sbjct: 1930 DSERWSGSASRNH--LGSAWEQSRDGSR-HPGSHHEDRAGHGHSADSSRQSGTRHTESSS 1986 Query: 213 SIAMMGQGSQGSSMMGQRPMAPYR-------------PSQQGSSQQYLGQEEYYGEQYSH 259 Q S G+R + ++ Q S+ + G Y G Q S Sbjct: 1987 RGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD 2046 Query: 260 SQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ---HYYEGGNSQYSQQ--- 313 S+G +E Q G Q S+ E + +S E S + Y+ + S+ Sbjct: 2047 SEGHSEDSDTQSV-SAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHG 2105 Query: 314 QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ 365 Q+ G Q Y Q Q S+ S Q+G + +G P G +QG Q+ Sbjct: 2106 QSAPSTGGRQGSHYDQAQDSSRHS--ASQEGQDTIRGHPGPSRGGRQGSHQE 2155 Score = 44.3 bits (103), Expect = 2e-04 Identities = 53/233 (22%), Positives = 86/233 (36%), Gaps = 31/233 (13%) Query: 184 NPVSMMQQQAATSHY--SSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQG 241 +P S + +A+ H SS Q G++H + S Q S G+R + ++ S Sbjct: 335 HPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADS 394 Query: 242 SSQQYLGQEEYY------------GEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQ 289 S G+ + G Q S S+G +E Q GHG +Q S+ E Sbjct: 395 SRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSV-SGHGKAGLRQQSHQES 453 Query: 290 SYDRSFEESTQHYYEGGNSQY----------SQQQAGYQQGAAQQQTYSQQQYPSQQSYP 339 + RS E S + G+S Y + + G G Q + Q + S+ S Sbjct: 454 TRGRSGERSGR----SGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHS-- 507 Query: 340 GQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYG 392 Q+G + +G P G +QG + R+ + G +G Sbjct: 508 ASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHG 560 Score = 43.9 bits (102), Expect = 3e-04 Identities = 69/319 (21%), Positives = 113/319 (35%), Gaps = 40/319 (12%) Query: 93 SGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTS-------- 144 SGS+ H + + P S + + +G S S +Q+ T+S Sbjct: 314 SGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSH 373 Query: 145 -MSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQG 203 + S PG H Q G + + ++ + + S QA+ S S Sbjct: 374 EQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSS-GSQASDSEGHSENS 432 Query: 204 GSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYY---------- 253 +Q G + Q Q S+ R + R + GSS + E Sbjct: 433 DTQSVSGHGKAGLRQQSHQEST----RGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTS 488 Query: 254 --GEQYSHSQGAAEPMGQQYYPDGH--------GDYAYQQSSYTEQSYDRSFEESTQHYY 303 G Q SH + A + +G +Q S+ EQS +RS + H + Sbjct: 489 TGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSH 548 Query: 304 --EGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQG 361 G S S Q+G + +A +QT +++Q + G + S+Q S++ Q G Sbjct: 549 TTSQGRSDASHGQSGSR--SASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHS--QVG 604 Query: 362 QGQQYGSYRAPQTAPSAQQ 380 QGQ G + S Q Sbjct: 605 QGQSSGPRTSRNQGSSVSQ 623 Score = 43.1 bits (100), Expect = 4e-04 Identities = 75/303 (24%), Positives = 119/303 (39%), Gaps = 31/303 (10%) Query: 86 GPGALTQSGSSQGL-HSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTS 144 G G S G H+Q S S+G SS Q + G H S Q S Sbjct: 669 GHGHSADSSRKSGTRHTQNS-----SSGQAASSHEQARSSAGERHGSRHQLQS----ADS 719 Query: 145 MSISGPGYSHAGPASQGVPMQG-QGTIGNYVSRTNINMQ-SNPVSMMQQQAATSHYSSAQ 202 SG G+ G AS V G +G+ G+ + + + + S+ S+ A H S Q Sbjct: 720 SRHSGTGH---GQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQ 776 Query: 203 GGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLG--QEEYYGEQYSHS 260 ++ G+ S + S + Q S G + G Q ++ + +S Sbjct: 777 ESARDRSGERS-------RRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNS 829 Query: 261 QGAAEPMGQQYYPDGHGDYAY-QQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGY 317 + +A GQ G +Q S+ EQS DRS + H + G S S+ Q+G Sbjct: 830 RHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGS 889 Query: 318 QQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPS 377 + +A + T +++Q + G + S+ S++ Q GQGQ GS + + S Sbjct: 890 R--SASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHS--QAGQGQSEGSRTSRRQGSS 945 Query: 378 AQQ 380 Q Sbjct: 946 VSQ 948 Score = 43.1 bits (100), Expect = 4e-04 Identities = 46/212 (21%), Positives = 76/212 (35%), Gaps = 21/212 (9%) Query: 199 SSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEE------- 251 SS Q G+ H + S + Q S G+R + ++ S S +G + Sbjct: 1325 SSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRD 1384 Query: 252 -----YYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFE---ESTQHYY 303 G Q ++S+G +E Q HG Q S+ E + +S E S Y Sbjct: 1385 SGHRGSSGSQVTNSEGHSEDSDTQSV-SAHGQAGPHQQSHKESARGQSGESSGRSRSFLY 1443 Query: 304 EGGNSQYSQQ---QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360 + + + S+ Q G Q + Q + S+ S Q G + +G P G +Q Sbjct: 1444 QVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHS--ASQDGQDTIRGHPGSSRGGRQ 1501 Query: 361 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYG 392 G + R+ + P G +G Sbjct: 1502 GSYHEQSVDRSGHSGYHHSHTTPQGRSDASHG 1533 Score = 40.8 bits (94), Expect = 0.002 Identities = 47/210 (22%), Positives = 75/210 (35%), Gaps = 11/210 (5%) Query: 191 QQAATSHYSSAQGG---SQHYQGQSSIAMM-GQGSQGSSMMGQRPMAPYRPSQQGSSQQY 246 +Q+ T H ++ GG S H Q +SS G Q S+ + P R Q S+ + Sbjct: 1003 RQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRR--QASSAVRD 1060 Query: 247 LGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYD----RSFEESTQHY 302 G G Q S S+G +E Q GHG Q S+ E + D RS + Y Sbjct: 1061 SGHWGSSGSQASDSEGHSEESDTQSV-SGHGQDGPHQQSHQESARDWSGGRSGRSGSFIY 1119 Query: 303 YEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQ 362 + Q + ++Q +Q + Q+G + + P G +QG Sbjct: 1120 QVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGS 1179 Query: 363 GQQYGSYRAPQTAPSAQQQRPYGYEQGQYG 392 + R+ + G +G Sbjct: 1180 HHEQSVDRSGHSGSHHSHTTSQGRSDASHG 1209 Score = 40.8 bits (94), Expect = 0.002 Identities = 67/297 (22%), Positives = 106/297 (35%), Gaps = 54/297 (18%) Query: 89 ALTQSGSSQGLHSQGSLSDAISTGLP---PSSLLQGQIGNGPSHVSMQQTAPNTLPTTSM 145 A + G G Q S + +G+P SS ++ G S + ++ + + Sbjct: 3294 ARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQ 3353 Query: 146 SISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGS 205 S+SG G AGP Q + G R+ S + Q + SA G + Sbjct: 3354 SVSGHG--QAGPHQQSHQESARDRSGGRSGRSG--------SFLYQVSTHEQSESAHGRT 3403 Query: 206 QHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265 + G+ QGS R + + SQ+G Q+ G S +G Sbjct: 3404 RTSTGRR---------QGSHHEQARDSSRHSASQEG-------QDTIRGHPGSSRRG--- 3444 Query: 266 PMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGYQQGAAQ 323 +Q S+ EQS DRS + H + G S S+ Q+G + +A Sbjct: 3445 ----------------RQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR--SAS 3486 Query: 324 QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380 +QT + +Q + S Q S++ Q GQGQ G + S Q Sbjct: 3487 RQTRNDEQSGDGSRHSWSHHHEASTQADSSRHS--QSGQGQSAGPRTSRNQGSSVSQ 3541 Score = 39.7 bits (91), Expect = 0.005 Identities = 48/198 (24%), Positives = 74/198 (37%), Gaps = 23/198 (11%) Query: 184 NPVSMMQQQAATSHY--SSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPS--- 238 +P S + +A H SS Q G+ H + S Q S G+R + ++ S Sbjct: 2281 HPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS 2340 Query: 239 ---------QQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQ 289 Q S+ + G G Q S S+G +E Q HG Q S+ E Sbjct: 2341 SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSV-SAHGQAGPHQQSHQES 2399 Query: 290 SYDRSFEESTQ---HYYEGGNSQYSQQ---QAGYQQGAAQQQTYSQQQYPSQQSYPGQQQ 343 + RS S + Y+ + S+ + G G Q + Q + S+ S Q+ Sbjct: 2400 TRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHS--TSQE 2457 Query: 344 GYGSAQGAPSQYPGYQQG 361 G + G P G +QG Sbjct: 2458 GQDTIHGHPGSSSGGRQG 2475 Score = 38.5 bits (88), Expect = 0.011 Identities = 68/317 (21%), Positives = 123/317 (38%), Gaps = 43/317 (13%) Query: 91 TQSGSSQGLHSQGSLSDAIS----TGLPPSSLLQGQIG-----NGPSHVSMQQTAPNTLP 141 +Q+ S+G HS+ S + ++S GL S + G +G S S+ Q + + P Sbjct: 420 SQASDSEG-HSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQP 478 Query: 142 T-----TSMSISGPGYSHAGPASQG----VPMQGQGTIGNYVSRTNINMQSN--PVSMMQ 190 T S G SH A +GQ TI + + Q + S+ + Sbjct: 479 DSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNR 538 Query: 191 QQAATSHYS--SAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ---- 244 + SH+S ++QG S GQS + ++ G + SSQ Sbjct: 539 SGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSS 598 Query: 245 --QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHY 302 +GQ + G + S +QG++ + Q GH + + + S +++ S +E ++ Sbjct: 599 RHSQVGQGQSSGPRTSRNQGSS--VSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSR-- 654 Query: 303 YEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQ 362 +G S + G + + +Q S GQ A S + + Sbjct: 655 -DGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQ---------AASSHEQARSSA 704 Query: 363 GQQYGSYRAPQTAPSAQ 379 G+++GS Q+A S++ Sbjct: 705 GERHGSRHQLQSADSSR 721 Score = 38.5 bits (88), Expect = 0.011 Identities = 64/284 (22%), Positives = 102/284 (35%), Gaps = 54/284 (19%) Query: 89 ALTQSGSSQGLHSQGSLSDAISTGL---PPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSM 145 A + +G G H Q S + +G+ SS ++ G S + ++ + + Sbjct: 2322 ARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQ 2381 Query: 146 SISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGS 205 S+S G AGP Q +G R+ S + Q + SA G + Sbjct: 2382 SVSAHG--QAGPHQQSHQESTRGRSAGRSGRSG--------SFLYQVSTHEQSESAHGRT 2431 Query: 206 QHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAE 265 G G QGS R + + SQ+G Q+ +G S S G Sbjct: 2432 GTSTG---------GRQGSHHKQARDSSRHSTSQEG-------QDTIHGHPGSSSGG--- 2472 Query: 266 PMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGYQQGAAQ 323 +Q S+ EQ DRS + H + G S S +G + +A Sbjct: 2473 ----------------RQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSR--SAS 2514 Query: 324 QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYG 367 +QT + +Q + G + S++ S + Q GQGQ G Sbjct: 2515 RQTRNDEQSGDGSRHSGSRHHEASSRADSSGHS--QVGQGQSEG 2556 Score = 38.1 bits (87), Expect = 0.014 Identities = 67/300 (22%), Positives = 109/300 (36%), Gaps = 40/300 (13%) Query: 91 TQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSM-SISG 149 T G S H Q A + + Q G+G H + P+T +S S G Sbjct: 1523 TPQGRSDASHGQSGPRSASR-----QTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVG 1577 Query: 150 PGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQH-- 207 G S S+ QG + S + S + A+ +HY SA+ S+H Sbjct: 1578 QGESAGSKTSR---RQGSSVSQDRDSEGH----SEDSERRSESASRNHYGSAREQSRHGS 1630 Query: 208 ---YQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQE--EYYGEQYSHSQG 262 Q A G ++ S G R Q SSQ+ E +G ++ S Sbjct: 1631 RNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSAD 1690 Query: 263 AAEPMGQQYYPD-------GHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQ-- 313 ++ G D G+ + Q+S +E + S +S + + G Q S Q Sbjct: 1691 SSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQES 1750 Query: 314 ---QAGYQQGAA-----QQQTYSQQQYPSQQSYP---GQQQGYGSAQGAPSQYPGYQQGQ 362 Q+G + G + Q T+ Q + ++ P G+Q+ S++ Q+GQ Sbjct: 1751 TRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQ 1810 Score = 38.1 bits (87), Expect = 0.014 Identities = 60/239 (25%), Positives = 94/239 (39%), Gaps = 19/239 (7%) Query: 166 GQGTIGNYVSRTNINMQSNPVSMMQ--QQAATSHYSSAQGGSQHYQGQSSIAMMG-QGSQ 222 G T G SR S+ S Q Q H S++GG Q Y + S+ G GS Sbjct: 2756 GPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSH 2815 Query: 223 GSSMMGQ-RPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAY 281 S Q R A S S+ + EE G+ HS G+ + A Sbjct: 2816 HSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHS-GSRHHEASTHADISRHSQAV 2874 Query: 282 QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAG----YQQGAAQQQTYSQQQYPSQQS 337 Q S + R +Q G+S+ S++ +G G+AQ+Q ++P +S Sbjct: 2875 QGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHP--RS 2932 Query: 338 YPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 + + G+G + + S+ G + Q G Q A S +Q R E ++G++ Q Sbjct: 2933 HQEDRAGHGHSADS-SRQSGTRHTQTSSGG-----QAASSHEQARSSAGE--RHGSHHQ 2983 Score = 38.1 bits (87), Expect = 0.014 Identities = 80/397 (20%), Positives = 136/397 (34%), Gaps = 89/397 (22%) Query: 89 ALTQSGSSQGLHSQGSLSDAISTGL---PPSSLLQ--GQIGNGPSHVSMQQTAPNTLPTT 143 A + +G G H Q S + +G+ SS ++ G G S S + T Sbjct: 2970 ARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQ 3029 Query: 144 SMSISGPGYSHAGP---ASQGVPMQGQGTIGNYVSRTNINMQS----------------- 183 S+S G SH +++G + G G+++ + + + QS Sbjct: 3030 SVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGS 3089 Query: 184 ----------NPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMG-QGSQGSSMMGQ-RP 231 + S Q H S++GG Q Y + S+ G GS S Q R Sbjct: 3090 RHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRS 3149 Query: 232 MAPYRPSQQGSSQQYLGQEEYYGEQYSHS--------------------QGAAE------ 265 A S S+ + EE G+ HS QG +E Sbjct: 3150 DASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSR 3209 Query: 266 ----PMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQH-------YYEG----GNSQY 310 + Q +GH + + + S +++ S +E ++H ++E G+S Sbjct: 3210 RQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSAD 3269 Query: 311 SQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGA-PSQYPGYQQGQGQ----- 364 +Q+G + + + +S PG++ G Q A S++ G +GQ Sbjct: 3270 RSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRD 3329 Query: 365 -----QYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 GS + S + GQ G +QQ Sbjct: 3330 SRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQ 3366 Score = 37.0 bits (84), Expect = 0.031 Identities = 59/287 (20%), Positives = 100/287 (34%), Gaps = 53/287 (18%) Query: 148 SGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPV----SMMQQQAATSHYS---- 199 +G G+S G P + + G + ++ +S+P S QQ A +S +S Sbjct: 993 AGHGHSADSSRQSGTP-HAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPR 1051 Query: 200 ----SAQGGSQHYQGQSSIAMMGQG----SQGSSMMGQRPMAPYRPSQQGSSQQYLG--- 248 SA S H+ S A +G S S+ G P++ S Q S++ + G Sbjct: 1052 RQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRS 1111 Query: 249 ---------------QEEYYGE--------QYSHSQGAAEPMGQQYYPDGHGDYAY---- 281 E +G Q SH + A + +G Sbjct: 1112 GRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGS 1171 Query: 282 ----QQSSYTEQSYDRSFEESTQHYY--EGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQ 335 +Q S+ EQS DRS + H + G S S Q+G + + Q + Q S+ Sbjct: 1172 RRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSR 1231 Query: 336 QSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQR 382 S + A + G +Q G + ++ + + +R Sbjct: 1232 HSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSER 1278 Score = 36.6 bits (83), Expect = 0.041 Identities = 51/214 (23%), Positives = 80/214 (37%), Gaps = 34/214 (15%) Query: 196 SHYS--SAQGGSQHYQGQSSIAMMG-------QGSQGSSMMGQRPMAPYRPSQQGSSQQY 246 SH+S ++QG S GQS Q GS G R + S Q S ++ Sbjct: 3786 SHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSR---HHEASTQADSSRH 3842 Query: 247 --LGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYE 304 GQ E G + S QG++ +Y E S RS S H+ Sbjct: 3843 SQSGQGESAGSRRSRRQGSSVSQDS------------DSEAYPEDSERRSESASRNHH-- 3888 Query: 305 GGNSQYSQQQAGYQQGAAQQQTYSQ-QQYPSQ-QSYPGQQQGYGSAQGAPSQYPGYQQGQ 362 G+S+ + G++ + T S Q P Q S ++ G+ S+ S Y Q + Sbjct: 3889 -GSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSR 3947 Query: 363 GQQYGSYRAPQTAPSAQQQRPYG---YEQGQYGN 393 G + S + ++Q+ + G YG+ Sbjct: 3948 GSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGS 3981 Score = 36.2 bits (82), Expect = 0.053 Identities = 55/264 (20%), Positives = 99/264 (37%), Gaps = 34/264 (12%) Query: 165 QGQGTIGNYVSRTNINMQSNPVSMMQQQA--ATSHYS--SAQGGSQHYQGQSSIAMMGQG 220 +GQ TI + + Q + ++ + SH+S ++QG S +GQS + Sbjct: 3429 EGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQ 3488 Query: 221 SQGSSMMGQRPMAPYRPSQQGSSQ------QYLGQEEYYGEQYSHSQGAAEPMGQQYYPD 274 ++ G + + S+Q GQ + G + S +QG++ + Q Sbjct: 3489 TRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSS--VSQDSDSQ 3546 Query: 275 GHGDYAYQQS---------SYTEQSYDRSFEESTQHYYEG--GNSQYSQQQAGYQQGAAQ 323 GH + + + S S EQS D S ++ H G+S S +Q+G Sbjct: 3547 GHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENS 3606 Query: 324 QQTYSQQQYPSQQSYPGQQQGYGSAQGA-PSQYPGYQQGQGQQYGSYRAPQTAPSAQQQR 382 + + +S G++ G Q A S++ G GQ + + +Q Sbjct: 3607 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASD 3666 Query: 383 PYGYEQ----------GQYGNYQQ 396 G+ + GQ G +QQ Sbjct: 3667 SEGHSEDSDTQSVSAHGQAGPHQQ 3690 Score = 35.8 bits (81), Expect = 0.069 Identities = 62/301 (20%), Positives = 100/301 (33%), Gaps = 31/301 (10%) Query: 87 PGALTQSGSSQGLHSQGSLSDAISTGLPPSSLL-QGQIGNGPSHVSMQQTAPNTLPTTSM 145 PG SG Q S S A G S++ +G G+ S S + T S+ Sbjct: 380 PGERHGSGHQQSADS--SRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSV 437 Query: 146 SISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQ----QAATSHYSSA 201 S G+ AG Q +G G R+ ++ VS +Q T + Sbjct: 438 S----GHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQ--VSTHEQPDSAHGRTGTSTGG 491 Query: 202 QGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQ 261 + GS H Q + S +S GQ + + S +G G Q SH + Sbjct: 492 RQGSHHEQARDS------SRHSASQEGQDTIRGHPGSSRG------------GRQGSHHE 533 Query: 262 GAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGA 321 + G H + + QS RS T++ + G+ ++ + Sbjct: 534 QSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASS 593 Query: 322 AQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQ 381 + Q Q S P + GS+ S G+ + + GS + +Q Sbjct: 594 QADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQS 653 Query: 382 R 382 R Sbjct: 654 R 654 Score = 35.0 bits (79), Expect = 0.12 Identities = 61/292 (20%), Positives = 101/292 (34%), Gaps = 30/292 (10%) Query: 115 PSSLLQGQIGNGPSHVSMQQTAPNTLPTTS---------MSISGPGYSHAGPASQGVPMQ 165 P S + + +G S S +Q+ T+S + S PG H Q Sbjct: 1633 PRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSS 1692 Query: 166 GQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYS--------SAQGGSQHYQGQSSIAMM 217 G + + N S Q + + +S SA G + +Q + Sbjct: 1693 TDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTR 1752 Query: 218 GQGSQGSSMMGQRPMAPYRPSQQGSSQQYLG------QEEYYGEQYSHSQGAAEPMGQQY 271 GQ + S G Q S+ G Q + + S+ +A GQ Sbjct: 1753 GQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDT 1812 Query: 272 YPDGHGDY-AYQQSSYTEQSYDRSFEESTQHYYEGG--NSQYSQQQAGYQQGAAQQQTYS 328 G +Q S+ EQS D S + H + S S+ Q+G + + +QT + Sbjct: 1813 IRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSR--SVSRQTRN 1870 Query: 329 QQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQ 380 ++Q + G + S++ S++ Q GQGQ G + S Q Sbjct: 1871 EKQSGDGSRHSGSRHHEASSRADSSRHS--QVGQGQSSGPRTSRNQGSSVSQ 1920 Score = 33.1 bits (74), Expect = 0.45 Identities = 43/180 (23%), Positives = 72/180 (40%), Gaps = 27/180 (15%) Query: 196 SHYS--SAQGGSQHYQGQSSIAMMG-------QGSQGSSMMGQR--PMAPYRPSQQGSSQ 244 SH+S ++QG S GQS Q GS G R A + S + S Sbjct: 1193 SHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQ- 1251 Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ---- 300 +GQE+ G + S QG++ + Q + H D + + S +++ S E ++ Sbjct: 1252 --VGQEQSSGSRTSRHQGSS--VSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSR 1307 Query: 301 ----HYYEG---GNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPS 353 H + G+S S +Q+G + + + +S PG++ G Q A S Sbjct: 1308 HPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADS 1367 Score = 30.8 bits (68), Expect = 2.2 Identities = 58/308 (18%), Positives = 105/308 (34%), Gaps = 20/308 (6%) Query: 62 ATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQG 121 + + DS S A ++ + + SG Q H Q S ++ S G Sbjct: 732 SAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSG 791 Query: 122 Q-IGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNIN 180 + +H + + T P+T + + GQ TI + + Sbjct: 792 SFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRG 851 Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240 Q S +Q S +S + QG+S + GS+ +S R S+ Sbjct: 852 RQG---SHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS----RTTRNEEQSRD 904 Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 GS ++ G + E SH+ + Q +G Q SS ++ S E ++ Sbjct: 905 GS--RHSGSRHH--EASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSE 960 Query: 301 HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360 ++S + +G+AQ+Q+ ++P G+ + S P + Sbjct: 961 --------RWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAET 1012 Query: 361 GQGQQYGS 368 G Q S Sbjct: 1013 SSGGQAAS 1020 >gi|33286444 mastermind-like 2 [Homo sapiens] Length = 1156 Score = 52.4 bits (124), Expect = 7e-07 Identities = 59/187 (31%), Positives = 69/187 (36%), Gaps = 14/187 (7%) Query: 204 GSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYS---HS 260 G Q + QSS G G S + M PS QG L Q++ S + Sbjct: 486 GQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNP 545 Query: 261 QGAAEPMGQQYYPDGH--GDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQ 318 A EP P H D A QQ S ++ S HY + Q QQQ Q Sbjct: 546 HPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKP---SLLHYTQQQQQQQQQQQQQQQ 602 Query: 319 QGAAQQQTYSQQQYPSQQ------SYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP 372 Q QQQ QQQ QQ QQQ SAQ Q QQ Q QQ + Sbjct: 603 QQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQ 662 Query: 373 QTAPSAQ 379 Q PS+Q Sbjct: 663 QQQPSSQ 669 Score = 48.1 bits (113), Expect = 1e-05 Identities = 79/307 (25%), Positives = 102/307 (33%), Gaps = 52/307 (16%) Query: 126 GPSHVSMQQTAPNTLPTTSMSISGPGYSH---AGPASQGVPMQGQGTIGNYVSRTNIN-- 180 GPS S Q P+ P SM+ S S + P SQ P G G S ++ Sbjct: 375 GPSG-SPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHA 433 Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQG-----SSMMGQRPMAPY 235 Q ++ +QQ A Q ++ S A G G S GQ+ +P Sbjct: 434 QQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQ 493 Query: 236 R---PSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYD 292 P G S Q Y + +QG GH D QQ Q Sbjct: 494 SSPMPGVAGGSGQSKVMANYMYKAGPSAQG------------GHLDVLMQQKP---QDLS 538 Query: 293 RSF-----------EESTQHYYEGGNSQYSQQQAG------------YQQGAAQQQTYSQ 329 RSF + +T+ + + Q +QQ Y Q QQQ Q Sbjct: 539 RSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQ 598 Query: 330 QQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQG 389 QQ QQ QQQ Q S QQ Q Q S + Q QQQ+ +Q Sbjct: 599 QQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQ 658 Query: 390 QYGNYQQ 396 Q QQ Sbjct: 659 QQQQQQQ 665 Score = 47.4 bits (111), Expect = 2e-05 Identities = 77/348 (22%), Positives = 109/348 (31%), Gaps = 52/348 (14%) Query: 67 SNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNG 126 +N + + P P P T SG+S+ L S +S A L+ N Sbjct: 394 ANSALSTSSPIPSVPQSQAQPQ--TGSGASRALPSWQEVSHA--------QQLKQIAANR 443 Query: 127 PSHVSMQQ----------------TAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQG-- 168 H MQQ P+ P I P + + Q PM G Sbjct: 444 QQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGG 503 Query: 169 -----TIGNYVSRTNINMQSNPVSMMQQQA----ATSHYSSAQGGSQHYQGQSSIAMMGQ 219 + NY+ + + Q + ++ QQ + S ++ + QG + Sbjct: 504 SGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFN 563 Query: 220 GSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDY 279 Q + M PSQ S + Q++ +Q Q + QQ Sbjct: 564 SDQANQQMPS-----VLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 618 Query: 280 AYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYP 339 Q S +Q + S Q + Q QQQ QQ QQQ S Q S S P Sbjct: 619 QQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQP 678 Query: 340 --------GQQQGYGSAQGAPSQYPGYQ--QGQGQQYGSYRAPQTAPS 377 Q+ Q P GYQ Q Q Q S T PS Sbjct: 679 LLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPS 726 >gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo sapiens] Length = 354 Score = 51.6 bits (122), Expect = 1e-06 Identities = 75/271 (27%), Positives = 97/271 (35%), Gaps = 43/271 (15%) Query: 128 SHVSMQQTAP--NTLPTTSMSISGPGYSH-AGPASQGVPMQGQGTIGNYVSRTNINMQSN 184 S+ Q TA T TS GY+ P + P+QG GT G Y + T + Sbjct: 51 SYTQAQTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGT-GAYDTTT-----AT 104 Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244 + AA S Y + A G Q ++ RP +P++ Q Sbjct: 105 VTTTQASYAAQSAYGTQP------------AYPAYGQQPAATAPTRPQDGNKPTETSQPQ 152 Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYE 304 G Y S + YP G Y Q + S+ + Y+ Sbjct: 153 SSTGGYNQPSLGYGQSNYS--------YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYD 204 Query: 305 GGNSQYSQQQA-GYQQGAAQQQTYSQQQYPSQQ---SYPGQQQGYGSAQGAPSQYPGYQQ 360 S YSQQ G QQ +Y QQ QQ SYP Q GS APSQY Sbjct: 205 --QSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQT---GSYSQAPSQYSQQSS 259 Query: 361 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391 GQQ S+R Q PS+ YG E G + Sbjct: 260 SYGQQ-SSFR--QDHPSS--MGVYGQESGGF 285 Score = 41.2 bits (95), Expect = 0.002 Identities = 51/220 (23%), Positives = 73/220 (33%), Gaps = 21/220 (9%) Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240 M S S Q AA YS+ +Q QG + G Q GQ Y +Q Sbjct: 1 MASTDYSTYSQAAAQQGYSAYT--AQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQT 57 Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 ++ YG+ + P G+G AY ++ T + S+ + Sbjct: 58 TATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSA 117 Query: 301 HYYEGGNSQYSQQQAGYQQGAAQ---QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357 + + Y QQ A Q + T + Q S Y GYG + + Q PG Sbjct: 118 YGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG 177 Query: 358 YQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391 Q P TAP S +P Y+Q Y Sbjct: 178 SYPMQ---------PVTAPPSYPPTSYSSTQPTSYDQSSY 208 >gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo sapiens] Length = 655 Score = 51.6 bits (122), Expect = 1e-06 Identities = 75/271 (27%), Positives = 97/271 (35%), Gaps = 43/271 (15%) Query: 128 SHVSMQQTAP--NTLPTTSMSISGPGYSH-AGPASQGVPMQGQGTIGNYVSRTNINMQSN 184 S+ Q TA T TS GY+ P + P+QG GT G Y + T + Sbjct: 51 SYTQAQTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGT-GAYDTTT-----AT 104 Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244 + AA S Y + A G Q ++ RP +P++ Q Sbjct: 105 VTTTQASYAAQSAYGTQP------------AYPAYGQQPAATAPTRPQDGNKPTETSQPQ 152 Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYE 304 G Y S + YP G Y Q + S+ + Y+ Sbjct: 153 SSTGGYNQPSLGYGQSNYS--------YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYD 204 Query: 305 GGNSQYSQQQA-GYQQGAAQQQTYSQQQYPSQQ---SYPGQQQGYGSAQGAPSQYPGYQQ 360 S YSQQ G QQ +Y QQ QQ SYP Q GS APSQY Sbjct: 205 --QSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQT---GSYSQAPSQYSQQSS 259 Query: 361 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391 GQQ S+R Q PS+ YG E G + Sbjct: 260 SYGQQ-SSFR--QDHPSS--MGVYGQESGGF 285 Score = 41.2 bits (95), Expect = 0.002 Identities = 51/220 (23%), Positives = 73/220 (33%), Gaps = 21/220 (9%) Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240 M S S Q AA YS+ +Q QG + G Q GQ Y +Q Sbjct: 1 MASTDYSTYSQAAAQQGYSAYT--AQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQT 57 Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 ++ YG+ + P G+G AY ++ T + S+ + Sbjct: 58 TATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSA 117 Query: 301 HYYEGGNSQYSQQQAGYQQGAAQ---QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357 + + Y QQ A Q + T + Q S Y GYG + + Q PG Sbjct: 118 YGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG 177 Query: 358 YQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391 Q P TAP S +P Y+Q Y Sbjct: 178 SYPMQ---------PVTAPPSYPPTSYSSTQPTSYDQSSY 208 >gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sapiens] Length = 656 Score = 51.6 bits (122), Expect = 1e-06 Identities = 75/271 (27%), Positives = 97/271 (35%), Gaps = 43/271 (15%) Query: 128 SHVSMQQTAP--NTLPTTSMSISGPGYSH-AGPASQGVPMQGQGTIGNYVSRTNINMQSN 184 S+ Q TA T TS GY+ P + P+QG GT G Y + T + Sbjct: 51 SYTQAQTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGT-GAYDTTT-----AT 104 Query: 185 PVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQ 244 + AA S Y + A G Q ++ RP +P++ Q Sbjct: 105 VTTTQASYAAQSAYGTQP------------AYPAYGQQPAATAPTRPQDGNKPTETSQPQ 152 Query: 245 QYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYE 304 G Y S + YP G Y Q + S+ + Y+ Sbjct: 153 SSTGGYNQPSLGYGQSNYS--------YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYD 204 Query: 305 GGNSQYSQQQA-GYQQGAAQQQTYSQQQYPSQQ---SYPGQQQGYGSAQGAPSQYPGYQQ 360 S YSQQ G QQ +Y QQ QQ SYP Q GS APSQY Sbjct: 205 --QSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQT---GSYSQAPSQYSQQSS 259 Query: 361 GQGQQYGSYRAPQTAPSAQQQRPYGYEQGQY 391 GQQ S+R Q PS+ YG E G + Sbjct: 260 SYGQQ-SSFR--QDHPSS--MGVYGQESGGF 285 Score = 41.2 bits (95), Expect = 0.002 Identities = 51/220 (23%), Positives = 73/220 (33%), Gaps = 21/220 (9%) Query: 181 MQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQ 240 M S S Q AA YS+ +Q QG + G Q GQ Y +Q Sbjct: 1 MASTDYSTYSQAAAQQGYSAYT--AQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQT 57 Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 ++ YG+ + P G+G AY ++ T + S+ + Sbjct: 58 TATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSA 117 Query: 301 HYYEGGNSQYSQQQAGYQQGAAQ---QQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPG 357 + + Y QQ A Q + T + Q S Y GYG + + Q PG Sbjct: 118 YGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG 177 Query: 358 YQQGQGQQYGSYRAPQTAP------SAQQQRPYGYEQGQY 391 Q P TAP S +P Y+Q Y Sbjct: 178 SYPMQ---------PVTAPPSYPPTSYSSTQPTSYDQSSY 208 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 51.6 bits (122), Expect = 1e-06 Identities = 92/418 (22%), Positives = 132/418 (31%), Gaps = 57/418 (13%) Query: 18 QQTIQKMLDE----NHHLIQCILEYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQS 73 Q IQK LD+ + EY++K + + Q QQ + V LA + + + Sbjct: 3571 QSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAV-LALSPSQSPRLLT 3629 Query: 74 LLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQ 133 LP L P G + GL P L GQ G + ++ Sbjct: 3630 KLPGQLLPGHGLQPPQGPPGGQAGGLRLT-----------PGGMALPGQPGGPFLNTALA 3678 Query: 134 QTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQA 193 Q + S++GP G + ++ G + + +Q + + Q+ Sbjct: 3679 QQQQQQHSGGAGSLAGPS---GGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQ 3735 Query: 194 ATSHYSSAQGGSQHYQGQSSIAMM---GQGSQGSSMMGQRPMAPYRPSQ-QGSSQQYLGQ 249 Q QH GQ +I G G Q + +G +P PS QG Q L Sbjct: 3736 QQQQQQQQQ---QHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSP 3792 Query: 250 EEYYGEQ-----------YSHSQGAAEPMGQ---------------QYYPDGHGDYAY-- 281 + G Q GA P G Q G G + Sbjct: 3793 QPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRL 3852 Query: 282 ---QQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSY 338 QQ +Q + H + S Q + Q + QQ QQQ QQ Sbjct: 3853 VTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQL 3912 Query: 339 PGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 QQQ Q Q QQ Q QQ + Q QQ + +Q Q QQ Sbjct: 3913 QQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQ 3970 Score = 47.4 bits (111), Expect = 2e-05 Identities = 68/250 (27%), Positives = 84/250 (33%), Gaps = 34/250 (13%) Query: 149 GPGYSH---AGPASQGV--PMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQG 203 GPG GP QG+ P QG + +S + Q + A G Sbjct: 3760 GPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALG 3819 Query: 204 GS----QHYQGQSSIAMMGQ-GSQGSSMMGQRPMAPYRPSQQGSSQQY---LGQEEYYGE 255 Q QS + Q QG +MG R + + QQ QQ G Sbjct: 3820 PQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQS 3879 Query: 256 QYSHS---QGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQ 312 SHS + +A+PMG QQ +Q Q + Q Q Sbjct: 3880 LMSHSGQPKLSAQPMGSLQQ--------LQQQQQLQQ----------QQQLQQQQQQQLQ 3921 Query: 313 QQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP 372 QQ QQ QQQ QQ QQ QQQ Q Q QQ Q QQ G Sbjct: 3922 QQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981 Query: 373 QTAPSAQQQR 382 +T S QQQ+ Sbjct: 3982 RTLLSPQQQQ 3991 Score = 45.4 bits (106), Expect = 9e-05 Identities = 80/330 (24%), Positives = 106/330 (32%), Gaps = 51/330 (15%) Query: 36 LEYQSKGKTAECTQYQQI-LHRNLVYLATIADSNQNMQS-----LLPAPPTQNMNLGPGA 89 L +S G + Q +Q+ L + + LA Q Q L Q GPG Sbjct: 3704 LALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGV 3763 Query: 90 LTQSG---SSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVS-MQQTAPNTLPTTSM 145 T QGL S + L P Q GP+ V+ +QQ P L Sbjct: 3764 QTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGAL----- 3818 Query: 146 SISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSH-YSSAQGG 204 GP GP Q V T + S+P Q Q H +AQ Sbjct: 3819 ---GP----QGPHRQ-------------VLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQ 3858 Query: 205 SQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAA 264 Q Q Q +M G S+M GS QQ Q++ +Q Q Sbjct: 3859 QQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQ 3918 Query: 265 EPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQ 324 + QQ QQ +Q + ++ Q + QQQ QQ QQ Sbjct: 3919 QLQQQQQL---------QQQQLQQQQQQQQLQQQQQQQLQ------QQQQQLQQQQQQQQ 3963 Query: 325 QTYSQQQYPSQQSYPGQQQGYGSAQGAPSQ 354 Q + QQQ Q Q + S Q Q Sbjct: 3964 QQFQQQQQQQQMGLLNQSRTLLSPQQQQQQ 3993 Score = 35.0 bits (79), Expect = 0.12 Identities = 91/376 (24%), Positives = 132/376 (35%), Gaps = 42/376 (11%) Query: 18 QQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSL--- 74 QQ +Q+ + Q L+ Q + + + Q QQ L+ + S Q Q Sbjct: 3937 QQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVA 3996 Query: 75 ----LPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLP--PSSLLQGQIGNGPS 128 +PA P Q+ + PGAL + G Q ++ A+S+ PS+ G + G + Sbjct: 3997 LGPGMPAKPLQHFS-SPGALGPTLLLTG-KEQNTVDPAVSSEATEGPSTHQGGPLAIGTT 4054 Query: 129 HVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSM 188 SM T P + + S P Q +Q Q + Q VS+ Sbjct: 4055 PESMA-TEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPL------RLPGQQQQQVSL 4107 Query: 189 MQQQAATSHYSSAQGGSQ------HYQGQSSIAMMGQ-GSQGSSMMG-QRPMAPYRPSQQ 240 + SH G S H Q S+++ Q GS +++G Q+PM RP Q Sbjct: 4108 LHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLE-RPMQN 4166 Query: 241 GSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQ 300 + Q G QG G P A Q + R Q Sbjct: 4167 NTGPQ----PPKPGPVLQSGQGLP---GVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219 Query: 301 HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQ 360 Q Q QQ A +QT Q+ P Q+ P QG Q +PG Q Sbjct: 4220 QQL-----QALLMQRQLQQSQAVRQTPPYQE-PGTQTSP--LQGLLGCQPQLGGFPGPQT 4271 Query: 361 GQGQQYGSYRAPQTAP 376 G Q+ G+ PQ P Sbjct: 4272 GPLQELGAGPRPQGPP 4287 Score = 29.3 bits (64), Expect = 6.5 Identities = 75/341 (21%), Positives = 117/341 (34%), Gaps = 59/341 (17%) Query: 92 QSGSSQGLHSQGSLSDAISTG----LPPSSLLQGQIGNGPSHVSMQQTAPNTL-PTTSMS 146 Q G GL Q S +S +PPS ++ P ++MQQ N+ P T + Sbjct: 3360 QHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMK------PQQLAMQQQLANSFFPDTDLD 3413 Query: 147 ------ISGPGYSHAGPASQGVP-MQGQGTIGNYVSRTNINMQSNPVSMMQQQAA----- 194 I P A +G+ + QG+IG M VS++ Q+ + Sbjct: 3414 KFAAEDIIDPIAKAKMVALKGIKKVMAQGSIG-----VAPGMNRQQVSLLAQRLSGGPSS 3468 Query: 195 -TSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRP----SQQGSSQQYLGQ 249 ++ +A G + G S + ++ + Y +QQ Q Sbjct: 3469 DLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVL 3528 Query: 250 EEYYG------EQYSHSQGAAEPMGQQYYPDGHGD---YAYQQSSYTEQSYDRSFEESTQ 300 EE G + Q A+ G+++ P+ + +Q S ++ D+ ++ + Sbjct: 3529 EEQIGVHRKSRKALCAKQRTAKKAGREF-PEADAEKLKLVTEQQSKIQKQLDQVRKQQKE 3587 Query: 301 HYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQS------YPGQ---QQGYGSAQGA 351 H + QQQ QQ QQQ + QS PGQ G QG Sbjct: 3588 HTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGP 3647 Query: 352 PSQY-------PGYQQGQGQQYGSYRAPQTAPSAQQQRPYG 385 P PG GQ G + A QQQ G Sbjct: 3648 PGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGG 3688 >gi|110347429 mediator complex subunit 12 [Homo sapiens] Length = 2177 Score = 50.1 bits (118), Expect = 4e-06 Identities = 90/348 (25%), Positives = 120/348 (34%), Gaps = 49/348 (14%) Query: 78 PPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQ--- 134 PP + PG++T QG + + + G P + P + MQ+ Sbjct: 1817 PPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYR------PVRLPMQKLPT 1870 Query: 135 --TAPNTLPTTSMSISG--------PGYSHAGPA-SQGVPM-----QGQGTIGNYVSRTN 178 T P LPTT + G Y PA QG + Q QG +G S + Sbjct: 1871 RPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQ--SSVH 1928 Query: 179 INMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQG--SSMMGQRP--MAP 234 S+ + Q T Y S G QH ++ SQ S+ P + P Sbjct: 1929 QMTPSSSYGLQTSQGYTP-YVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDP 1987 Query: 235 YRPSQQGSSQQYLGQEEYYG------EQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTE 288 R QQ S Q YG +++SH PM P S+ Sbjct: 1988 TRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTP---------MSAQGV 2038 Query: 289 QSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSA 348 Q+ RS + + Q QQQ QQ QQQ Y +Q QQ QQQ Sbjct: 2039 QAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQ 2098 Query: 349 QGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396 Q Q QQ Q QQ+ + Q AP Q +P Q Q QQ Sbjct: 2099 QQQQQQQQQQQQQQQQQHQQQQQQQAAP--PQPQPQSQPQFQRQGLQQ 2144 Score = 46.6 bits (109), Expect = 4e-05 Identities = 77/274 (28%), Positives = 99/274 (36%), Gaps = 51/274 (18%) Query: 101 SQGSLSDAISTGLPPSSL--LQGQIGNGP--SHVSMQQTAPNTLPTTSMSISGPGYSHAG 156 SQG L + + PSS LQ G P SHV +QQ +GP + Sbjct: 1918 SQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQH------------TGPAGTMVP 1965 Query: 157 PASQGVPMQGQ--GTIGNYVSRTNINMQSNPVSMMQQQAATSHY---SSAQGGSQHYQGQ 211 P+ P Q T V T ++Q P + QQA T + S+ + Q Q Sbjct: 1966 PSYSSQPYQSTHPSTNPTLVDPTR-HLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQT 2024 Query: 212 SSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQY 271 I+ M S G R A QQ QQ Q++ +Q Q QQY Sbjct: 2025 PMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQ-------QQY 2077 Query: 272 YPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQ 331 H QQ +Q + ++ Q Q QQQ QQQ + QQQ Sbjct: 2078 ----HIRQQQQQQILRQQQQQQQQQQQQQQ-----QQQQQQQQ--------QQQQHQQQQ 2120 Query: 332 YPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQ 365 QQ+ P Q Q Q Q G QQ Q QQ Sbjct: 2121 --QQQAAPPQPQPQSQPQ---FQRQGLQQTQQQQ 2149 >gi|57165375 glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 [Homo sapiens] Length = 371 Score = 49.3 bits (116), Expect = 6e-06 Identities = 40/135 (29%), Positives = 46/135 (34%), Gaps = 26/135 (19%) Query: 229 QRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDY---AYQQSS 285 Q PM PY Q Y G Y P GQ YP G Y Y Q Sbjct: 26 QPPMPPY------------AQPPYPGAPYPQPPFQPSPYGQPGYPHGPSPYPQGGYPQGP 73 Query: 286 YTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQ---- 341 Y + Y + Y + G Q Q GY QG Q + Y Q +PGQ Sbjct: 74 YPQGGYPQG------PYPQEGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDPDS 127 Query: 342 -QQGYGSAQGAPSQY 355 Q G +G PS Y Sbjct: 128 PQHGNYQEEGPPSYY 142 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.123 0.350 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,930,089 Number of Sequences: 37866 Number of extensions: 874487 Number of successful extensions: 6132 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 83 Number of HSP's successfully gapped in prelim test: 286 Number of HSP's that attempted gapping in prelim test: 3350 Number of HSP's gapped (non-prelim): 1242 length of query: 396 length of database: 18,247,518 effective HSP length: 104 effective length of query: 292 effective length of database: 14,309,454 effective search space: 4178360568 effective search space used: 4178360568 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.