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Search of human proteins with 38683799
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38683799 ankyrin repeat domain 13 [Homo sapiens]
(590 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38683799 ankyrin repeat domain 13 [Homo sapiens] 1187 0.0
gi|124517699 ankyrin repeat domain 13B [Homo sapiens] 588 e-168
gi|46409340 ankyrin repeat domain 13 family, member D [Homo sapi... 506 e-143
gi|166795254 ankyrin repeat domain 13C [Homo sapiens] 253 5e-67
gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 54 4e-07
gi|24233530 ankyrin repeat domain 44 [Homo sapiens] 54 5e-07
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 53 7e-07
gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens] 52 2e-06
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 52 2e-06
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 52 2e-06
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 52 2e-06
gi|51972284 NOTCH-regulated ankyrin repeat protein [Homo sapiens] 52 2e-06
gi|223634006 hypothetical protein LOC441869 [Homo sapiens] 51 3e-06
gi|14150169 acyl-coenzyme A binding domain containing 6 [Homo sa... 51 3e-06
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 51 3e-06
gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 1... 51 3e-06
gi|68131557 ankyrin repeat domain 28 [Homo sapiens] 50 4e-06
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 50 4e-06
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 50 4e-06
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 50 4e-06
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 50 4e-06
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 50 4e-06
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 50 4e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens] 50 8e-06
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 49 1e-05
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 49 1e-05
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 49 1e-05
gi|7705748 TNNI3 interacting kinase isoform b [Homo sapiens] 49 1e-05
gi|163914396 TNNI3 interacting kinase isoform a [Homo sapiens] 49 1e-05
gi|14249672 protein phosphatase 1, regulatory (inhibitor) subuni... 49 1e-05
>gi|38683799 ankyrin repeat domain 13 [Homo sapiens]
Length = 590
Score = 1187 bits (3070), Expect = 0.0
Identities = 590/590 (100%), Positives = 590/590 (100%)
Query: 1 MSSACDAGDHYPLHLLVWKNDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVL 60
MSSACDAGDHYPLHLLVWKNDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVL
Sbjct: 1 MSSACDAGDHYPLHLLVWKNDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVL 60
Query: 61 LRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLQKILEAP 120
LRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLQKILEAP
Sbjct: 61 LRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLQKILEAP 120
Query: 121 DFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKG 180
DFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKG
Sbjct: 121 DFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKG 180
Query: 181 EDNWAELMEVNHDDKVVTTERFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKN 240
EDNWAELMEVNHDDKVVTTERFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKN
Sbjct: 181 EDNWAELMEVNHDDKVVTTERFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKN 240
Query: 241 IAFERTKSGFWGWRTDKAEVVNGYEAKVYTVNNVNVITKIRTEHLTEEEKKRYKADRNPL 300
IAFERTKSGFWGWRTDKAEVVNGYEAKVYTVNNVNVITKIRTEHLTEEEKKRYKADRNPL
Sbjct: 241 IAFERTKSGFWGWRTDKAEVVNGYEAKVYTVNNVNVITKIRTEHLTEEEKKRYKADRNPL 300
Query: 301 ESLLGTVEHQFGAQGDLTTECATANNPTAITPDEYFNEEFDLKDRDIGRPKELTIRTQKF 360
ESLLGTVEHQFGAQGDLTTECATANNPTAITPDEYFNEEFDLKDRDIGRPKELTIRTQKF
Sbjct: 301 ESLLGTVEHQFGAQGDLTTECATANNPTAITPDEYFNEEFDLKDRDIGRPKELTIRTQKF 360
Query: 361 KAMLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLEFPPGFPVKIEIPLFHVLN 420
KAMLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLEFPPGFPVKIEIPLFHVLN
Sbjct: 361 KAMLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLEFPPGFPVKIEIPLFHVLN 420
Query: 421 ARITFGNVNGCSTAEESVSQNVEGTQADSASHITNFEVDQSVFEIPESYYVQDNGRNVHL 480
ARITFGNVNGCSTAEESVSQNVEGTQADSASHITNFEVDQSVFEIPESYYVQDNGRNVHL
Sbjct: 421 ARITFGNVNGCSTAEESVSQNVEGTQADSASHITNFEVDQSVFEIPESYYVQDNGRNVHL 480
Query: 481 QDEDYEIMQFAIQQSLLESSRSQELSGPASNGGISQTNTYDAQYERAIQESLLTSTEGLC 540
QDEDYEIMQFAIQQSLLESSRSQELSGPASNGGISQTNTYDAQYERAIQESLLTSTEGLC
Sbjct: 481 QDEDYEIMQFAIQQSLLESSRSQELSGPASNGGISQTNTYDAQYERAIQESLLTSTEGLC 540
Query: 541 PSALSETSRFDNDLQLAMELSAKELEEWELRLQEEEAELQQVLQLSLTDK 590
PSALSETSRFDNDLQLAMELSAKELEEWELRLQEEEAELQQVLQLSLTDK
Sbjct: 541 PSALSETSRFDNDLQLAMELSAKELEEWELRLQEEEAELQQVLQLSLTDK 590
>gi|124517699 ankyrin repeat domain 13B [Homo sapiens]
Length = 626
Score = 588 bits (1516), Expect = e-168
Identities = 312/611 (51%), Positives = 409/611 (66%), Gaps = 31/611 (5%)
Query: 11 YPLHLLVWKNDYRQLEKELQ-GQ-NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVT 68
YPLH LVW N +R+LEKE++ GQ ++E +DPRGRT LHLA +LGHLE ARVLL H ADV
Sbjct: 16 YPLHYLVWHNRHRELEKEVRAGQVDIEQLDPRGRTPLHLATTLGHLECARVLLAHGADVG 75
Query: 69 KENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLQKILEAPDFYVQMKW 128
+ENR GWTVL EAVST D E+V VL++RDY L G+P LL+K+ +A DFYV+MKW
Sbjct: 76 RENRSGWTVLQEAVSTRDLELVQLVLRYRDYQRVVKRLAGIPVLLEKLRKAQDFYVEMKW 135
Query: 129 EFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKGEDNWAELM 188
EFTSWVPLVS+ICP+D ++WKSG LRVD TLLGF++M+W RG RSF+F+G+D A +M
Sbjct: 136 EFTSWVPLVSKICPSDTYKVWKSGQNLRVDTTLLGFDHMTWQRGNRSFVFRGQDTSAVVM 195
Query: 189 EVNHDDKVVTTERFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNIAFERTKS 248
E++HD +VV TE L+ + L L +P +V RLT+PV+ T LDTKNI+FER K+
Sbjct: 196 EIDHDRRVVYTETLALAGQDRELLLAAAQPTEEQVLSRLTAPVVTTQLDTKNISFERNKT 255
Query: 249 GFWGWRTDKAEVVNGYEAKVYTVNNVNVITKIRTEHLTEEEKKRYKADRNPLESLLGTVE 308
G GWR++K E+VNGYEAKVY +NV +IT+ RTEHL+E+ K + K + PL+S LG E
Sbjct: 256 GILGWRSEKTEMVNGYEAKVYGASNVELITRTRTEHLSEQHKGKVKGCKTPLQSFLGIAE 315
Query: 309 HQFGAQ-GDLTTECATANNPTAITPDEYFNEEFDLKDRDIGRPKELTIRTQKFKAMLWMC 367
G Q G L T+ + NPTAIT +EYFN F+L +RD+GRP ELT +TQKFKA LW+C
Sbjct: 316 QHGGPQNGTLITQTLSQANPTAITAEEYFNPNFELGNRDMGRPMELTTKTQKFKAKLWLC 375
Query: 368 EEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLEFPPGFPVKIEIPLFHVLNARITFGN 427
EE PLSL EQV PIIDLMA ++A FA+LRDFI L PPGFPVKIEIP+FH+LNARITFGN
Sbjct: 376 EEHPLSLCEQVAPIIDLMAVSNALFAKLRDFITLRLPPGFPVKIEIPIFHILNARITFGN 435
Query: 428 VNGC---------STAEESVSQNVEGTQADSASHITN---FEVDQSVFEIPESYYVQDNG 475
+NGC S + E+ S + + S+S T+ E+ ++FE P Y +
Sbjct: 436 LNGCDEPVPSVRGSPSSETPSPGSDSSSVSSSSSTTSCRGCEISPALFEAPRGYSMMGGQ 495
Query: 476 RNVHLQDEDYEIMQFAIQQSLLESSRSQELSGPASNGGISQTNTYDAQYERAIQESLLTS 535
R +D+D +++QFAIQQSLLE+ + S+ T+ YE Q+
Sbjct: 496 REAATRDDDDDLLQFAIQQSLLEAGSEYDQVTIWEALTNSKPGTHPMSYEGRRQDRSAPP 555
Query: 536 TEGLCPSALSET----------------SRFDNDLQLAMELSAKELEEWELRLQEEEAEL 579
T P+ + +D L+LAMELSA+E EE R ++EE EL
Sbjct: 556 TPQRQPAPPASVPSPRPSSGPGSGGHVFRSYDEQLRLAMELSAQEQEERRRRARQEEEEL 615
Query: 580 QQVLQLSLTDK 590
+++L+LSLT++
Sbjct: 616 ERILRLSLTEQ 626
>gi|46409340 ankyrin repeat domain 13 family, member D [Homo
sapiens]
Length = 518
Score = 506 bits (1302), Expect = e-143
Identities = 264/518 (50%), Positives = 348/518 (67%), Gaps = 18/518 (3%)
Query: 89 MVYTVLQHRDYHNTSMALEGVPELLQKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRI 148
MV VLQ+RDY + L G+PELL K+ +APDFYV+MKWEFTSWVPLVS++CP+DV R+
Sbjct: 1 MVQLVLQYRDYQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRV 60
Query: 149 WKSGAKLRVDITLLGFENMSWIRGRRSFIFKGEDNWAELMEVNHDDKVVTTERFDLSQEM 208
WK G LRVD +LLGFE+++W RGRRSFIFKG++ A +MEV+HD +VV E L+ +
Sbjct: 61 WKRGESLRVDTSLLGFEHVTWQRGRRSFIFKGQEAGALVMEVDHDRQVVHVETLGLTLQE 120
Query: 209 ERLTLDLMKPKSREVERRLTSPVINTSLDTKNIAFERTKSGFWGWRTDKAEVVNGYEAKV 268
L M+P V RLTSP+++T LDT+N+AFER K G WGWR++K E V+GYEAKV
Sbjct: 121 PETLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKV 180
Query: 269 YTVNNVNVITKIRTEHLTEEEKKRYKADRNPLESLLGTVEHQFGAQGDLTTECATANNPT 328
Y+ NV ++T+ RTEHL++++K R KA + P +S LG + G + A+ NPT
Sbjct: 181 YSATNVELVTRTRTEHLSDQDKSRSKAGKTPFQSFLGMAQQHSSHTGAPVQQAASPTNPT 240
Query: 329 AITPDEYFNEEFDLKDRDIGRPKELTIRTQKFKAMLWMCEEFPLSLVEQVIPIIDLMART 388
AI+P+EYF+ F L+ R+IGRP E++ + Q+FKA LW+ EE PLSL +QV PIIDLMA +
Sbjct: 241 AISPEEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAIS 300
Query: 389 SAHFARLRDFIKLEFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEESVSQNVEGTQAD 448
+AHFA+LRDFI L PPGFPVKIEIPLFHVLNARITF N+ GC SV +
Sbjct: 301 NAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPLSSVWVPAPSSAVA 360
Query: 449 SASHITNFEVDQSVFEIPESYYVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQEL--- 505
++ + EVD +VFE+P Y V RN L+DED +++QFAIQQSLLE+ E
Sbjct: 361 ASGNPFPCEVDPTVFEVPNGYSVLGMERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTV 420
Query: 506 ------SGPASNGGISQTNTYD--AQYERAIQESLLTSTEGLCPSALSET------SRFD 551
+ P + Q Y+ Q ERA+QESL STE P + T F+
Sbjct: 421 WEALTNTRPGARPP-PQATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPAPGPPSFE 479
Query: 552 NDLQLAMELSAKELEEWELRLQEEEAELQQVLQLSLTD 589
L+LA+ELS++E EE E R Q+EE +LQ++LQLSLT+
Sbjct: 480 EQLRLALELSSREQEERERRGQQEEEDLQRILQLSLTE 517
>gi|166795254 ankyrin repeat domain 13C [Homo sapiens]
Length = 541
Score = 253 bits (645), Expect = 5e-67
Identities = 151/416 (36%), Positives = 233/416 (56%), Gaps = 16/416 (3%)
Query: 10 HYPLHLLVWKNDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTK 69
HYP+H V+K D R+L ++ N+ D G T LHLAV LG+ E A +LL H A V
Sbjct: 113 HYPVHECVFKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKV 172
Query: 70 ENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLQKILEAPDFYVQMKWE 129
+N QGW+ L EA+S GD +M+ +L+ + E P LL+ + E DFY+++ W+
Sbjct: 173 KNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWD 232
Query: 130 FTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKGEDNWAELME 189
F SWVPL+SRI P+D C+I+K G +R+D TL+ F +M RG SFIF G+ +E
Sbjct: 233 FQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFV 292
Query: 190 VNHDDKVVTTERFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNIAFERTKSG 249
V +++ V EME EV+ ++S + + +L TK+I+F R ++G
Sbjct: 293 VLDNEQKVYQRIHHEESEME---------TEEEVDILMSSDIYSATLSTKSISFTRAQTG 343
Query: 250 FWGWRTDKAEVVNGYEAKVYTVNNVNVITKIRTEHLTEEEKKRYKADRNPLESLLGTVEH 309
W +R DK E V + A Y VN + + ++ R EHL+EE+ R KA L +E
Sbjct: 344 -WLFREDKTERVGNFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQ 402
Query: 310 QFGAQGDLTTECATANNPTAITPDEYFNEEFDLKDRDIGRPKELTIRTQKFKAMLWMCEE 369
F + + T IT +EY + E + K +GR + FKA + M +E
Sbjct: 403 NF---EPIRRQSLTPPPQNTITWEEYISAE-NGKAPHLGRELVCKESKKTFKATIAMSQE 458
Query: 370 FPLSLVEQVIPIIDLMARTSAHFARLRDFIKLEFPPGFPVKIEIPLFHVLNARITF 425
FPL +E ++ +++++A HF +LR+F++++ PPGFPVK++IP+F + A +TF
Sbjct: 459 FPLG-IELLLNVLEVVA-PFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTF 512
>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
Length = 1429
Score = 53.9 bits (128), Expect = 4e-07
Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHK 64
DA L++L +N E L+ G NVEA D GRT LH++ GH+E +VL+ +
Sbjct: 943 DADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYH 1002
Query: 65 ADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
ADV + + + L A G ++V +++H
Sbjct: 1003 ADVNAADNEKRSALQSAAWQGHVKVVQLLIEH 1034
Score = 42.4 bits (98), Expect = 0.001
Identities = 21/55 (38%), Positives = 30/55 (54%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTG 85
G V+++D GRT+L +A + G++E R LL D + GWT LH A G
Sbjct: 804 GAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEG 858
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 7/101 (6%)
Query: 5 CDAGDHYPLHLLVWKNDYRQLEKELQG-QNVEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
CD PL + ++ ++ L+G +V+ D GRT L A S+GH LL
Sbjct: 744 CDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFW 803
Query: 64 KADVTKENRQGWTVLHEAVSTGDPEMVYTVL------QHRD 98
A V + +G TVL A + G+ E+V T+L HRD
Sbjct: 804 GAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRD 844
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 4 ACDAGDHYPLHLLVWKNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLLR 62
A DA LH+ W+ ++ + +V A D R+ L A GH++ ++L+
Sbjct: 974 ASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIE 1033
Query: 63 HKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
H A V QG T L A G ++V +L+H
Sbjct: 1034 HGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEH 1067
Score = 39.7 bits (91), Expect = 0.008
Identities = 24/66 (36%), Positives = 32/66 (48%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G V+ D RT L A GH + LL+H A+V K + +G T L A G E+V
Sbjct: 634 GVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIV 693
Query: 91 YTVLQH 96
+L H
Sbjct: 694 EHLLDH 699
Score = 39.3 bits (90), Expect = 0.010
Identities = 21/65 (32%), Positives = 32/65 (49%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G ++E D G T L LA GH + L+ A++ ++ GWT L A G E+
Sbjct: 567 RGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEV 626
Query: 90 VYTVL 94
V +L
Sbjct: 627 VSALL 631
Score = 36.6 bits (83), Expect = 0.066
Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 2/108 (1%)
Query: 12 PLHLLVWKNDYRQLEKEL-QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ ++ E + QG +D GR LA GH + ++LL +K+++ +
Sbjct: 850 PLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQR 909
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLQKILE 118
G L A G ++V + H N A +G P L LE
Sbjct: 910 GYDGRNALRVAALEGHRDIVELLFSHGADVNCKDA-DGRPTLYILALE 956
Score = 35.8 bits (81), Expect = 0.11
Identities = 27/77 (35%), Positives = 31/77 (40%), Gaps = 1/77 (1%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHK 64
DA L W + LQ G V D GRT L A +GH E LL H
Sbjct: 641 DADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHG 700
Query: 65 ADVTKENRQGWTVLHEA 81
A+V E+ G T L A
Sbjct: 701 AEVNHEDVDGRTALSVA 717
Score = 35.8 bits (81), Expect = 0.11
Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Query: 3 SACDAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLL 61
+A D L W+ + ++ ++ G V+ +G T L +A GH++ +VLL
Sbjct: 1006 NAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLL 1065
Query: 62 RHKADVTKENRQGWTVLHEAVSTGDPEMV 90
H AD ++ G T + A G +++
Sbjct: 1066 EHGADPNHADQFGRTAMRVAAKNGHSQII 1094
Score = 35.4 bits (80), Expect = 0.15
Identities = 23/65 (35%), Positives = 32/65 (49%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G V+ D G T L +A GH++ +LL ADV + G T L A S G +
Sbjct: 737 RGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASV 796
Query: 90 VYTVL 94
V T+L
Sbjct: 797 VNTLL 801
Score = 33.1 bits (74), Expect = 0.73
Identities = 21/60 (35%), Positives = 29/60 (48%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G +V D GRTLL A G L+ +L+ AD+ E+ G T L A G ++V
Sbjct: 535 GASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVV 594
Score = 32.7 bits (73), Expect = 0.96
Identities = 19/66 (28%), Positives = 30/66 (45%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G +V D GR L++ L A L + A+V + +G T LH + G EMV
Sbjct: 936 GADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMV 995
Query: 91 YTVLQH 96
++ +
Sbjct: 996 QVLIAY 1001
Score = 32.0 bits (71), Expect = 1.6
Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 1/92 (1%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHK 64
DA H PL L + + + + G N+ D G T L A GH E LL
Sbjct: 575 DAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAG 634
Query: 65 ADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
V + T L A G ++V +LQH
Sbjct: 635 VKVDCADADSRTALRAAAWGGHEDIVLNLLQH 666
>gi|24233530 ankyrin repeat domain 44 [Homo sapiens]
Length = 919
Score = 53.5 bits (127), Expect = 5e-07
Identities = 25/65 (38%), Positives = 40/65 (61%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G N+ A D + R LH A +GHL+ +L+ H A+VT ++++G+T LH A S G +
Sbjct: 137 KGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINV 196
Query: 90 VYTVL 94
V +L
Sbjct: 197 VKHLL 201
Score = 46.2 bits (108), Expect = 8e-05
Identities = 32/88 (36%), Positives = 46/88 (52%), Gaps = 4/88 (4%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVD---PRGRTLLHLAVSLGHLESARVLLRHKADV 67
PLH V L L+ N EAVD +G+T L LAV+ GH+++ +LL +A+V
Sbjct: 612 PLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANV 671
Query: 68 TKENRQGWTVLHEAVSTGDPEMVYTVLQ 95
+ G T LH + TG E V +L+
Sbjct: 672 DTVDILGCTALHRGIMTGHEECVQMLLE 699
Score = 41.6 bits (96), Expect = 0.002
Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 3/71 (4%)
Query: 25 LEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVST 84
LEKE NV+ VD G T LH + GH E ++LL + + ++ +G T LH A +
Sbjct: 665 LEKEA---NVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAAR 721
Query: 85 GDPEMVYTVLQ 95
G + +LQ
Sbjct: 722 GHATWLSELLQ 732
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKE-LQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHK 64
D+ PLH+ + D +E L G V A D T LH AV+ E+ +VL++H
Sbjct: 13 DSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHS 72
Query: 65 ADVTKENRQGWTVLHEAVS 83
ADV ++ T LH A +
Sbjct: 73 ADVNARDKNWQTPLHVAAA 91
Score = 41.2 bits (95), Expect = 0.003
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Query: 12 PLHLLVWKNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADV-TK 69
PLHL + ++ LE LQ +++ D +GRT L LA GH E L+ A + K
Sbjct: 545 PLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINPGASIFVK 604
Query: 70 ENRQGWTVLHEAVSTGDPEMVYTVLQHRD 98
+N T LH +V G + +L+ D
Sbjct: 605 DNVTKRTPLHASVINGHTLCLRLLLEIAD 633
Score = 39.7 bits (91), Expect = 0.008
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 2 SSACDAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVL 60
++ C +PLHL K L G ++ D GRT LH A + G++E ++L
Sbjct: 340 TAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLL 399
Query: 61 LRHKADVTKENRQGWTVLHEAVS 83
AD K+++ G T LH A +
Sbjct: 400 QSSGADFHKKDKCGRTPLHYAAA 422
Score = 38.9 bits (89), Expect = 0.013
Identities = 21/65 (32%), Positives = 34/65 (52%)
Query: 32 QNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVY 91
++V +D RT LH+A LG E +L+ A V ++ T LH AV++ E V
Sbjct: 7 EDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQ 66
Query: 92 TVLQH 96
+++H
Sbjct: 67 VLIKH 71
Score = 37.0 bits (84), Expect = 0.051
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 5/78 (6%)
Query: 12 PLHLLVWKNDYRQLEKELQG----QNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADV 67
PLH + ND+ L G V D +GRT L A H+E ++LLRH A V
Sbjct: 782 PLHCAII-NDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPV 840
Query: 68 TKENRQGWTVLHEAVSTG 85
+ G T L A G
Sbjct: 841 NAVDNSGKTALMMAAENG 858
Score = 36.2 bits (82), Expect = 0.087
Identities = 20/64 (31%), Positives = 32/64 (50%)
Query: 33 NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYT 92
+V D GRT LH A GH+E +LL A++ +++ LH A G ++V
Sbjct: 107 SVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVAL 166
Query: 93 VLQH 96
++ H
Sbjct: 167 LINH 170
Score = 35.0 bits (79), Expect = 0.19
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH V ++ ++ +V A D +T LH+A + ++ A V++ + V
Sbjct: 52 PLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVS 111
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVL 94
+R G T LH A G EMV +L
Sbjct: 112 DRGGRTALHHAALNGHVEMVNLLL 135
Score = 34.3 bits (77), Expect = 0.33
Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G + D GRT LH A + H L+ A+V + + G T LH A ++ D +
Sbjct: 403 GADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAAS-DMDRN 461
Query: 91 YTVLQHRDYHNTSMALEGVPELLQK 115
T+L + H+ S LE EL +K
Sbjct: 462 KTILGNA--HDNSEELERARELKEK 484
Score = 33.5 bits (75), Expect = 0.56
Identities = 20/66 (30%), Positives = 30/66 (45%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G V D +G T LH A S G + + LL ++ + N G T LH A G +V
Sbjct: 171 GAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVV 230
Query: 91 YTVLQH 96
++ +
Sbjct: 231 NELIDY 236
Score = 33.1 bits (74), Expect = 0.73
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHK 64
D + PLH ++ L G ++ ++ G T LH+A G L+ +
Sbjct: 178 DKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYG 237
Query: 65 ADVTKENRQGWTVLHEAVST 84
A+V + N G+T LH A ++
Sbjct: 238 ANVNQPNNNGFTPLHFAAAS 257
Score = 30.4 bits (67), Expect = 4.8
Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 34 VEAVDPRGRTLLHLAVSLGHLESARVLLRH-KADVTKENRQGWTVLHEAVSTGDPEMVYT 92
V AVD G+T L +A G + +L+ +AD+T +++ T LH A S G +
Sbjct: 840 VNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALL 899
Query: 93 VL 94
+L
Sbjct: 900 IL 901
Score = 30.0 bits (66), Expect = 6.2
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ + + + +Q G ++ VD G T LH+A GH L AD K
Sbjct: 284 PLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGADTAKC 343
Query: 71 NRQGWTVLHEA 81
LH A
Sbjct: 344 GIHSMFPLHLA 354
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 53.1 bits (126), Expect = 7e-07
Identities = 34/86 (39%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH +E LQ G NV+A D G LH A S GH E +LLRH AD
Sbjct: 61 PLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNAR 120
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
+ +T LHEA G ++ +LQH
Sbjct: 121 DNWNYTPLHEAAIKGKIDVCIVLLQH 146
Score = 51.2 bits (121), Expect = 3e-06
Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH N +E LQ G +V A D G LH A S GH E A +L++H A V
Sbjct: 529 PLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVA 588
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
+ +T LHEA + G E+ +LQH
Sbjct: 589 DLWKFTPLHEAAAKGKYEICKLLLQH 614
Score = 51.2 bits (121), Expect = 3e-06
Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLHL N+ E LQ G +V A D G LH A S GH++ A +L+++ A V
Sbjct: 682 PLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNAT 741
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
++ +T LHEA G ++ +L H
Sbjct: 742 DKWAFTPLHEAAQKGRTQLCALLLAH 767
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 8/121 (6%)
Query: 4 ACDAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLR 62
A D PLHL N + ++ LQ G +V A D LH A S GH E +L++
Sbjct: 206 ASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVK 265
Query: 63 HKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH------RDYHNTS-MALEGVPELLQK 115
H A V + +T LHEA S E+ +L + + HN S + L P+L ++
Sbjct: 266 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKER 325
Query: 116 I 116
+
Sbjct: 326 L 326
Score = 44.3 bits (103), Expect = 3e-04
Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 2/75 (2%)
Query: 24 QLEKELQGQNVEAVDPRGR--TLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEA 81
+++K NV D +GR T LHLA +LE A LL+H ADV +++ G LH A
Sbjct: 660 RVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNA 719
Query: 82 VSTGDPEMVYTVLQH 96
S G ++ ++++
Sbjct: 720 ASYGHVDVAALLIKY 734
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/87 (36%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 4 ACDAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLR 62
A D G PLH Y E ++ G V D T LH A + G E ++LL+
Sbjct: 554 AKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQ 613
Query: 63 HKADVTKENRQGWTVLHEAVSTGDPEM 89
H AD TK+NR G T L + V GD ++
Sbjct: 614 HGADPTKKNRDGNTPL-DLVKDGDTDI 639
Score = 40.0 bits (92), Expect = 0.006
Identities = 22/64 (34%), Positives = 34/64 (53%)
Query: 33 NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYT 92
N A D R T LHLA ++ ++LL+H ADV +++ LH A S G E+
Sbjct: 203 NCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTEL 262
Query: 93 VLQH 96
+++H
Sbjct: 263 LVKH 266
Score = 39.3 bits (90), Expect = 0.010
Identities = 21/68 (30%), Positives = 33/68 (48%)
Query: 29 LQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPE 88
+Q N ++ R T LH A + LL+H ADV +++ G LH A S G E
Sbjct: 514 VQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYE 573
Query: 89 MVYTVLQH 96
+ +++H
Sbjct: 574 VAELLVKH 581
Score = 38.1 bits (87), Expect = 0.023
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Query: 21 DYRQLEKELQGQNVEAVDPRGR--TLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVL 78
D ++++ + + V + D GR T LH A G + LL++ A+V + G L
Sbjct: 36 DVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPL 95
Query: 79 HEAVSTGDPEMVYTVLQH 96
H A S G E+V +L+H
Sbjct: 96 HNACSFGHAEVVNLLLRH 113
Score = 38.1 bits (87), Expect = 0.023
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 12/89 (13%)
Query: 12 PLHLLVWKNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ K +E ++ + V A+D G+T LH A GHL++ R+LL + D
Sbjct: 403 PLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNII 462
Query: 71 NRQGWT-----------VLHEAVSTGDPE 88
+ QG+T +L E +S G+ E
Sbjct: 463 SLQGFTALQMGNENVQQLLQEGISLGNSE 491
Score = 33.1 bits (74), Expect = 0.73
Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 9/95 (9%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G N+ T LH+A H + V+++H+A V + G T LH A G +
Sbjct: 389 KGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQT 448
Query: 90 VYTVLQH---------RDYHNTSMALEGVPELLQK 115
+L + + + M E V +LLQ+
Sbjct: 449 CRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQE 483
>gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens]
Length = 777
Score = 52.0 bits (123), Expect = 2e-06
Identities = 26/64 (40%), Positives = 39/64 (60%)
Query: 40 RGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQHRDY 99
RG TLLH+A G + S LL++ +D ++ GWT LHEA + G ++V +LQH+
Sbjct: 427 RGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKAL 486
Query: 100 HNTS 103
NT+
Sbjct: 487 VNTT 490
Score = 45.8 bits (107), Expect = 1e-04
Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 13 LHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKEN 71
LH+ K D +E LQ G + D G T LH A + GHL+ +LL+HKA V
Sbjct: 432 LHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTG 491
Query: 72 RQGWTVLHEAVSTGDPEMVYTVLQH 96
Q + LH+A G ++V +L +
Sbjct: 492 YQNDSPLHDAAKNGHVDIVKLLLSY 516
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/86 (32%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ + D +Q+++ + G NV D G T LH A ++G+ + A++L+ ADV +
Sbjct: 165 PLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQ 224
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
T LH++ S+G ++V +L+H
Sbjct: 225 GLDDDTPLHDSASSGHRDIVKLLLRH 250
Score = 38.9 bits (89), Expect = 0.013
Identities = 20/56 (35%), Positives = 30/56 (53%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTG 85
Q V + RG T LH+A G ++ + L+ A+V ++ GWT LHEA + G
Sbjct: 151 QKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVG 206
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/86 (32%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ + D +Q+++ + G NV D G T LH A ++G+ + A++L+ ADV +
Sbjct: 188 PLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQ 247
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
T LH++ S+G ++V +L+H
Sbjct: 248 GLDDDTPLHDSASSGHRDIVKLLLRH 273
Score = 38.9 bits (89), Expect = 0.013
Identities = 20/56 (35%), Positives = 30/56 (53%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTG 85
Q V + RG T LH+A G ++ + L+ A+V ++ GWT LHEA + G
Sbjct: 174 QKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVG 229
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 51.6 bits (122), Expect = 2e-06
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ KN + +E L+ G +++AV G T +H+A +GH+ L+ H A
Sbjct: 403 PLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTT 462
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQ 95
N +G T LH A +G E+V ++Q
Sbjct: 463 NVRGETALHMAARSGQAEVVRYLVQ 487
Score = 48.9 bits (115), Expect = 1e-05
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKEL-QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLHL ++ E + QG +V+A G T LH+ G+++ LL+H A V +
Sbjct: 700 PLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAK 759
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
+ G+T LH+A G ++ +LQ+
Sbjct: 760 TKNGYTPLHQAAQQGHTHIINVLLQN 785
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Query: 9 DHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADV 67
D PLH+ +++ LQ G + A G T LHL+ GH + A LL H A +
Sbjct: 499 DQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASL 558
Query: 68 TKENRQGWTVLHEAVSTGDPEMVYTVLQ 95
+ ++G+T LH A G E+ +LQ
Sbjct: 559 SITTKKGFTPLHVAAKYGKLEVANLLLQ 586
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
Query: 5 CDAGDHYPLHLLVWKNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
C+ LHL + + + LQ + NV+A +G T LH+A G E +VL+ +
Sbjct: 70 CNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTN 129
Query: 64 KADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
A+V +++ G+T L+ A E+V +L +
Sbjct: 130 GANVNAQSQNGFTPLYMAAQENHLEVVKFLLDN 162
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ KN L+ G + AV +G +HLA GH++ +LL A+V
Sbjct: 634 PLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLS 693
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQHRDYH 100
N+ G T LH A D V VL ++ H
Sbjct: 694 NKSGLTPLHLAAQE-DRVNVAEVLVNQGAH 722
Score = 39.7 bits (91), Expect = 0.008
Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 25 LEKELQ----GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHE 80
LEK L G ++ + G LHLA GH+E LL+ +A+V ++G T LH
Sbjct: 54 LEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHI 113
Query: 81 AVSTGDPEMV 90
A G E+V
Sbjct: 114 ASLAGQAEVV 123
Score = 38.5 bits (88), Expect = 0.017
Identities = 22/65 (33%), Positives = 30/65 (46%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
QG + A G T LH+A ++ A LL + AD RQG +H A G +M
Sbjct: 620 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDM 679
Query: 90 VYTVL 94
V +L
Sbjct: 680 VSLLL 684
Score = 38.5 bits (88), Expect = 0.017
Identities = 22/64 (34%), Positives = 32/64 (50%)
Query: 33 NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYT 92
NV + G T LHLA + A VL+ A V + + G+T LH G+ ++V
Sbjct: 689 NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNF 748
Query: 93 VLQH 96
+LQH
Sbjct: 749 LLQH 752
Score = 37.0 bits (84), Expect = 0.051
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
Query: 12 PLHLLVWKNDYRQLEKELQGQNVEAVDPRGR--TLLHLAVSLGHLESARVLLRHKADVTK 69
PLH+ + D+ + L NV D T LH+A GH + A+VLL KA+
Sbjct: 337 PLHMAT-QGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNA 395
Query: 70 ENRQGWTVLHEAVSTGDPEMVYTVLQH 96
+ G+T LH A +++ +L+H
Sbjct: 396 KALNGFTPLHIACKKNRIKVMELLLKH 422
Score = 36.6 bits (83), Expect = 0.066
Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
P+H+ + + + + G + + RG T LH+A G E R L++ A V +
Sbjct: 436 PIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAK 495
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQ 95
+ T LH + G ++V +LQ
Sbjct: 496 AKDDQTPLHISARLGKADIVQQLLQ 520
Score = 35.8 bits (81), Expect = 0.11
Identities = 21/66 (31%), Positives = 33/66 (50%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G NV A G T L++A HLE + LL + A + G+T L A+ G ++V
Sbjct: 130 GANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVV 189
Query: 91 YTVLQH 96
+L++
Sbjct: 190 SLLLEN 195
Score = 35.8 bits (81), Expect = 0.11
Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 1/89 (1%)
Query: 9 DHYPLHLLVWKNDYRQLEKEL-QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADV 67
D PLH+ + + ++ L +G ++A G T LH GH + +LL A +
Sbjct: 268 DITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPI 327
Query: 68 TKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
+ + G + LH A V +LQH
Sbjct: 328 LSKTKNGLSPLHMATQGDHLNCVQLLLQH 356
Score = 34.3 bits (77), Expect = 0.33
Identities = 20/71 (28%), Positives = 31/71 (43%)
Query: 33 NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYT 92
N A G T LH+A ++ +LL+H A + G T +H A G +V
Sbjct: 392 NPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQ 451
Query: 93 VLQHRDYHNTS 103
++ H NT+
Sbjct: 452 LMHHGASPNTT 462
Score = 33.5 bits (75), Expect = 0.56
Identities = 19/66 (28%), Positives = 30/66 (45%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G VEA +T LH++ LG + + LL+ A G+T LH + G ++
Sbjct: 489 GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVA 548
Query: 91 YTVLQH 96
+L H
Sbjct: 549 AFLLDH 554
Score = 31.2 bits (69), Expect = 2.8
Identities = 17/48 (35%), Positives = 24/48 (50%)
Query: 48 AVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQ 95
A GHLE A +++ D+ N+ G LH A G E+V +LQ
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQ 95
Score = 30.4 bits (67), Expect = 4.8
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 41 GRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQHRDYH 100
G + LH+A HL ++LL+H V T LH A G ++ +L +
Sbjct: 334 GLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANP 393
Query: 101 NTSMALEGVPEL 112
N + AL G L
Sbjct: 394 N-AKALNGFTPL 404
Score = 30.0 bits (66), Expect = 6.2
Identities = 32/116 (27%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ + + + LQ V A G T LH A GH VLL++ A +
Sbjct: 733 PLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNEL 792
Query: 71 NRQGWTVLHEAVSTGDPEMVYTV-LQHRDYHNTSMALE----GVPELLQKILEAPD 121
G T L A G +V T+ + + T+ E VPE + ++L+ D
Sbjct: 793 TVNGNTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPETMNEVLDMSD 848
>gi|51972284 NOTCH-regulated ankyrin repeat protein [Homo sapiens]
Length = 114
Score = 51.6 bits (122), Expect = 2e-06
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 5/88 (5%)
Query: 17 VWKNDYRQLEKELQGQ-----NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKEN 71
V K + ++L+ LQ NV + P G+T LH +V G+LE ++L++ AD+ N
Sbjct: 22 VRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLAN 81
Query: 72 RQGWTVLHEAVSTGDPEMVYTVLQHRDY 99
R GW+ LH A G ++V ++ Y
Sbjct: 82 RDGWSALHIAAFGGHQDIVLYLITKAKY 109
>gi|223634006 hypothetical protein LOC441869 [Homo sapiens]
Length = 399
Score = 51.2 bits (121), Expect = 3e-06
Identities = 36/85 (42%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Query: 14 HLL--VWKNDYRQLEKEL-QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
HLL VW+ + + L QG +VE D GRT LHLAV GH R+LL+ A V
Sbjct: 44 HLLQAVWRGPAGLVTQLLRQGASVEERDHAGRTPLHLAVLRGHAPLVRLLLQRGAPVGAV 103
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQ 95
+R G T LHEA G + +LQ
Sbjct: 104 DRAGRTALHEAAWHGHSRVAELLLQ 128
Score = 43.5 bits (101), Expect = 5e-04
Identities = 32/91 (35%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHK 64
D PLHL V + + LQ G V AVD GRT LH A GH A +LL+
Sbjct: 71 DHAGRTPLHLAVLRGHAPLVRLLLQRGAPVGAVDRAGRTALHEAAWHGHSRVAELLLQRG 130
Query: 65 ADVTKENRQGWTVLHEAVSTGDPEMVYTVLQ 95
A + G T LH A + G + +L+
Sbjct: 131 ASAAARSGTGLTPLHWAAALGHTLLAARLLE 161
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/56 (41%), Positives = 30/56 (53%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTG 85
+G V+A D G T L LA +LG + VLL H AD +R G + LH A + G
Sbjct: 225 RGARVDARDGAGATALGLAAALGRSQDIEVLLGHGADPGIRDRHGRSALHRAAARG 280
Score = 36.6 bits (83), Expect = 0.066
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 38 DPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVL 94
D GR+ LH A + GHL + ++L+ A+V + G T LH A G E+ +L
Sbjct: 266 DRHGRSALHRAAARGHLLAVQLLVTQGAEVDARDTLGLTPLHHASREGHVEVAGCLL 322
>gi|14150169 acyl-coenzyme A binding domain containing 6 [Homo
sapiens]
Length = 282
Score = 51.2 bits (121), Expect = 3e-06
Identities = 28/79 (35%), Positives = 45/79 (56%), Gaps = 2/79 (2%)
Query: 19 KNDYRQLEKELQGQNVEA--VDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWT 76
+N+ + K ++ +NV+ D GR LLH A GH E VLL+H+AD+ ++ +G T
Sbjct: 168 ENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQT 227
Query: 77 VLHEAVSTGDPEMVYTVLQ 95
LH A + ++V +LQ
Sbjct: 228 ALHYASACEFLDIVELLLQ 246
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 51.2 bits (121), Expect = 3e-06
Identities = 36/94 (38%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Query: 4 ACDAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLR 62
A D PLHL N R ++ LQ G +V A D G LH A S GH E +LL+
Sbjct: 364 ASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLK 423
Query: 63 HKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
H A V + +T LHEA S E+ +L H
Sbjct: 424 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSH 457
Score = 50.1 bits (118), Expect = 6e-06
Identities = 33/86 (38%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH N +E L G +V A D G LH A S GH E A +L+RH A V
Sbjct: 687 PLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVA 746
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
+ +T LHEA + G E+ +L+H
Sbjct: 747 DLWKFTPLHEAAAKGKYEICKLLLKH 772
Score = 48.5 bits (114), Expect = 2e-05
Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLHL N+ E L+ G +V A D G LH A S GH++ A +L+++ V
Sbjct: 840 PLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNAT 899
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
++ +T LHEA G ++ +L H
Sbjct: 900 DKWAFTPLHEAAQKGRTQLCALLLAH 925
Score = 46.2 bits (108), Expect = 8e-05
Identities = 32/86 (37%), Positives = 39/86 (45%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH +E LQ G NV A D G LH A S GH E +LL AD
Sbjct: 219 PLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNAR 278
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
+ +T LHEA G ++ +LQH
Sbjct: 279 DNWNYTPLHEAAIKGKIDVCIVLLQH 304
Score = 45.1 bits (105), Expect = 2e-04
Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Query: 24 QLEKELQGQNVEAVDPRGR--TLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEA 81
+++K +N+ D +GR T LHLA +LE A LL H ADV +++ G LH A
Sbjct: 818 RVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNA 877
Query: 82 VSTGDPEMVYTVLQHRDYHNTS 103
S G ++ ++++ N +
Sbjct: 878 ASYGHVDIAALLIKYNTCVNAT 899
Score = 43.5 bits (101), Expect = 5e-04
Identities = 24/64 (37%), Positives = 34/64 (53%)
Query: 33 NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYT 92
N A D R T LHLA + ++LL+H ADV +++ G LH A S G E+
Sbjct: 361 NCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTEL 420
Query: 93 VLQH 96
+L+H
Sbjct: 421 LLKH 424
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Query: 4 ACDAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLR 62
A D G PLH Y E ++ G +V D T LH A + G E ++LL+
Sbjct: 712 AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLK 771
Query: 63 HKADVTKENRQGWTVLHEAVSTGDPEM 89
H AD TK+NR G T L + V GD ++
Sbjct: 772 HGADPTKKNRDGNTPL-DLVKEGDTDI 797
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/89 (33%), Positives = 38/89 (42%), Gaps = 13/89 (14%)
Query: 21 DYRQLEKELQG-----------QNVEAVDPRGR--TLLHLAVSLGHLESARVLLRHKADV 67
DYR LE G QNV D GR T LH A + LL H ADV
Sbjct: 651 DYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADV 710
Query: 68 TKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
+++ G LH A S G E+ +++H
Sbjct: 711 HAKDKGGLVPLHNACSYGHYEVAELLVRH 739
Score = 38.9 bits (89), Expect = 0.013
Identities = 23/67 (34%), Positives = 39/67 (58%), Gaps = 3/67 (4%)
Query: 12 PLHLLVWK--NDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTK 69
PLH+ + ND ++ + G + A+D G+T LH A GHL++ R+LL + +D +
Sbjct: 561 PLHVAAERAHNDVMEVLHK-HGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSI 619
Query: 70 ENRQGWT 76
+ QG+T
Sbjct: 620 ISLQGFT 626
Score = 33.9 bits (76), Expect = 0.43
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 21 DYRQLEKELQGQNVEAVDPRGR--TLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVL 78
D ++++ + NV A D GR + LH A G + LL+ A+V + G L
Sbjct: 194 DVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPL 253
Query: 79 HEAVSTGDPEMVYTVL 94
H A S G E+V +L
Sbjct: 254 HNACSFGHAEVVSLLL 269
Score = 31.6 bits (70), Expect = 2.1
Identities = 27/72 (37%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 4 ACDAGDHYPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLR 62
A D G PLH Y E L+ G V A+D T LH A S +E +LL
Sbjct: 397 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 456
Query: 63 HKADVTKENRQG 74
H AD T N G
Sbjct: 457 HGADPTLVNCHG 468
Score = 30.8 bits (68), Expect = 3.6
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTG 85
+G NV + T LH+A H + VL +H A + + G T LH A G
Sbjct: 547 KGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAG 602
>gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 16B
[Homo sapiens]
Length = 567
Score = 50.8 bits (120), Expect = 3e-06
Identities = 25/80 (31%), Positives = 45/80 (56%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
GQ+++ +D +G TLLH+A + G+L +A +LL H V ++ GW LH A G +M
Sbjct: 219 GQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMA 278
Query: 91 YTVLQHRDYHNTSMALEGVP 110
++ H + +++ +P
Sbjct: 279 ELLVSHGASLSARTSMDEMP 298
Score = 34.7 bits (78), Expect = 0.25
Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 19 KNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTV 77
+ND ++ L+ + + + + G T LH E ++LL H A+V ++ + WT
Sbjct: 78 RNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTP 137
Query: 78 LHEAVSTGDPEMVYTVLQH 96
LH A + G +V ++Q+
Sbjct: 138 LHAAATCGHINLVKILVQY 156
Score = 33.1 bits (74), Expect = 0.73
Identities = 16/44 (36%), Positives = 24/44 (54%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQG 74
G NV A D T LH A + GH+ ++L+++ AD+ N G
Sbjct: 124 GANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDG 167
>gi|68131557 ankyrin repeat domain 28 [Homo sapiens]
Length = 1053
Score = 50.4 bits (119), Expect = 4e-06
Identities = 21/56 (37%), Positives = 37/56 (66%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTG 85
+G N+ A D + R +H A +GH+E ++L+ H A+VT ++++ +T LH A S+G
Sbjct: 162 RGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSG 217
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 12 PLHLLVWKNDYRQLEKE-LQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH + D +E L G V A D + T LH AV+ E+ +VLL+H ADV
Sbjct: 44 PLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNAR 103
Query: 71 NRQGWTVLHEAVS 83
++ T LH A +
Sbjct: 104 DKNWQTPLHIAAA 116
Score = 41.6 bits (96), Expect = 0.002
Identities = 24/63 (38%), Positives = 33/63 (52%)
Query: 34 VEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTV 93
V+ D G+T L L+V GH + LL A+V +++ G T LH TG E V +
Sbjct: 646 VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDAL 705
Query: 94 LQH 96
LQH
Sbjct: 706 LQH 708
Score = 41.2 bits (95), Expect = 0.003
Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 11 YPLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTK 69
+PLHL K L G +++ D GRT LH A + G+LE +LL AD K
Sbjct: 374 FPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNK 433
Query: 70 ENRQGWTVLHEAVSTGDPEMVYTVL 94
+++ G + LH A + + + ++ ++
Sbjct: 434 KDKFGRSPLHYAAANCNYQCLFALV 458
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/66 (34%), Positives = 34/66 (51%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G NV+A D GRT LH GH E LL+H A + +G T +H + + G +
Sbjct: 675 KGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGV 734
Query: 90 VYTVLQ 95
+ +LQ
Sbjct: 735 LGALLQ 740
Score = 40.4 bits (93), Expect = 0.005
Identities = 28/82 (34%), Positives = 35/82 (42%), Gaps = 3/82 (3%)
Query: 12 PLHLLVWKNDYRQLEK---ELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVT 68
PLH V ++ E L V A D +GRT LH A H+E ++LL H A V
Sbjct: 791 PLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVN 850
Query: 69 KENRQGWTVLHEAVSTGDPEMV 90
+ G T L A G V
Sbjct: 851 SVDSTGKTPLMMAAENGQTNTV 872
Score = 38.1 bits (87), Expect = 0.023
Identities = 21/64 (32%), Positives = 32/64 (50%)
Query: 33 NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYT 92
NV D GRT LH A GH E ++LL A++ +++ +H A G E+V
Sbjct: 132 NVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKL 191
Query: 93 VLQH 96
++ H
Sbjct: 192 LVSH 195
Score = 37.0 bits (84), Expect = 0.051
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Query: 12 PLHLLVWKNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADV-TK 69
PLHL + ++ LE +Q +++ + GRT L LA GH+E VL+ A + K
Sbjct: 553 PLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVK 612
Query: 70 ENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHN 101
+ T +H A + G E + ++ + + N
Sbjct: 613 DYILKRTPIHAAATNGHSECLRLLIGNAEPQN 644
Score = 36.2 bits (82), Expect = 0.087
Identities = 22/65 (33%), Positives = 33/65 (50%)
Query: 32 QNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVY 91
++V D RT LH A LG E +L+ A V ++ + T LH AV++ E V
Sbjct: 32 EDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQ 91
Query: 92 TVLQH 96
+L+H
Sbjct: 92 VLLKH 96
Score = 35.8 bits (81), Expect = 0.11
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ + + + +Q G ++ D G T LH+A GH L+ AD K
Sbjct: 309 PLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR 368
Query: 71 NRQGWTVLHEAVSTG 85
G LH A +G
Sbjct: 369 GIHGMFPLHLAALSG 383
Score = 35.8 bits (81), Expect = 0.11
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 38 DPRGRTLLHLAVSLGHLESARVLLRHKADV----TKENRQGWTVLHEAVSTGDPEMVYTV 93
D RGRT +HL+ + GH+ LL+ A + + G+T LH A G V +
Sbjct: 716 DSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELL 775
Query: 94 LQHRDYHNT 102
L+ + T
Sbjct: 776 LEQEVFQKT 784
Score = 30.4 bits (67), Expect = 4.8
Identities = 16/64 (25%), Positives = 31/64 (48%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G +V G+T LH+ G ++ +++ A + E++ G T LH A G ++
Sbjct: 296 GADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLI 355
Query: 91 YTVL 94
T++
Sbjct: 356 NTLI 359
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 50.4 bits (119), Expect = 4e-06
Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 3 SACDAGDHYPLHLLVWKNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLL 61
+A D H LHL + + + K LQ + E+VD G+T LH A + G L++ ++L
Sbjct: 83 TAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILC 142
Query: 62 RHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
HK+ + ++ G L AV G E+ + +L H
Sbjct: 143 EHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDH 177
Score = 48.9 bits (115), Expect = 1e-05
Identities = 23/68 (33%), Positives = 36/68 (52%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G + D G+T HLA + GH+E RV++ H DVT ++ G + LH A E
Sbjct: 45 KGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHEC 104
Query: 90 VYTVLQHR 97
+ +LQ +
Sbjct: 105 IRKLLQSK 112
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/83 (32%), Positives = 37/83 (44%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G +V A D G + LHLA H E R LL+ K + G T LH A + G + V
Sbjct: 79 GVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAV 138
Query: 91 YTVLQHRDYHNTSMALEGVPELL 113
+ +H+ N +P LL
Sbjct: 139 QILCEHKSPINLKDLDGNIPLLL 161
Score = 30.8 bits (68), Expect = 3.6
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKEL--QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
D + PL LL +N + ++ L G +V + + GRT L LA +G + L++
Sbjct: 152 DLDGNIPL-LLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 210
Query: 64 KADVTKENRQGWTVLH 79
AD+ + G+ LH
Sbjct: 211 GADLNLVDSLGYNALH 226
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 50.4 bits (119), Expect = 4e-06
Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 3 SACDAGDHYPLHLLVWKNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLL 61
+A D H LHL + + + K LQ + E+VD G+T LH A + G L++ ++L
Sbjct: 72 TAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILC 131
Query: 62 RHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
HK+ + ++ G L AV G E+ + +L H
Sbjct: 132 EHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDH 166
Score = 48.9 bits (115), Expect = 1e-05
Identities = 23/68 (33%), Positives = 36/68 (52%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G + D G+T HLA + GH+E RV++ H DVT ++ G + LH A E
Sbjct: 34 KGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHEC 93
Query: 90 VYTVLQHR 97
+ +LQ +
Sbjct: 94 IRKLLQSK 101
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/83 (32%), Positives = 37/83 (44%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G +V A D G + LHLA H E R LL+ K + G T LH A + G + V
Sbjct: 68 GVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAV 127
Query: 91 YTVLQHRDYHNTSMALEGVPELL 113
+ +H+ N +P LL
Sbjct: 128 QILCEHKSPINLKDLDGNIPLLL 150
Score = 30.8 bits (68), Expect = 3.6
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKEL--QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
D + PL LL +N + ++ L G +V + + GRT L LA +G + L++
Sbjct: 141 DLDGNIPL-LLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 199
Query: 64 KADVTKENRQGWTVLH 79
AD+ + G+ LH
Sbjct: 200 GADLNLVDSLGYNALH 215
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 50.4 bits (119), Expect = 4e-06
Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 3 SACDAGDHYPLHLLVWKNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLL 61
+A D H LHL + + + K LQ + E+VD G+T LH A + G L++ ++L
Sbjct: 80 TAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILC 139
Query: 62 RHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
HK+ + ++ G L AV G E+ + +L H
Sbjct: 140 EHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDH 174
Score = 48.9 bits (115), Expect = 1e-05
Identities = 23/68 (33%), Positives = 36/68 (52%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G + D G+T HLA + GH+E RV++ H DVT ++ G + LH A E
Sbjct: 42 KGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHEC 101
Query: 90 VYTVLQHR 97
+ +LQ +
Sbjct: 102 IRKLLQSK 109
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/83 (32%), Positives = 37/83 (44%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G +V A D G + LHLA H E R LL+ K + G T LH A + G + V
Sbjct: 76 GVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAV 135
Query: 91 YTVLQHRDYHNTSMALEGVPELL 113
+ +H+ N +P LL
Sbjct: 136 QILCEHKSPINLKDLDGNIPLLL 158
Score = 30.8 bits (68), Expect = 3.6
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKEL--QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
D + PL LL +N + ++ L G +V + + GRT L LA +G + L++
Sbjct: 149 DLDGNIPL-LLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 207
Query: 64 KADVTKENRQGWTVLH 79
AD+ + G+ LH
Sbjct: 208 GADLNLVDSLGYNALH 223
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 50.4 bits (119), Expect = 4e-06
Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 3 SACDAGDHYPLHLLVWKNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLL 61
+A D H LHL + + + K LQ + E+VD G+T LH A + G L++ ++L
Sbjct: 80 TAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILC 139
Query: 62 RHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
HK+ + ++ G L AV G E+ + +L H
Sbjct: 140 EHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDH 174
Score = 48.9 bits (115), Expect = 1e-05
Identities = 23/68 (33%), Positives = 36/68 (52%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G + D G+T HLA + GH+E RV++ H DVT ++ G + LH A E
Sbjct: 42 KGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHEC 101
Query: 90 VYTVLQHR 97
+ +LQ +
Sbjct: 102 IRKLLQSK 109
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/83 (32%), Positives = 37/83 (44%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G +V A D G + LHLA H E R LL+ K + G T LH A + G + V
Sbjct: 76 GVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAV 135
Query: 91 YTVLQHRDYHNTSMALEGVPELL 113
+ +H+ N +P LL
Sbjct: 136 QILCEHKSPINLKDLDGNIPLLL 158
Score = 30.8 bits (68), Expect = 3.6
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKEL--QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
D + PL LL +N + ++ L G +V + + GRT L LA +G + L++
Sbjct: 149 DLDGNIPL-LLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 207
Query: 64 KADVTKENRQGWTVLH 79
AD+ + G+ LH
Sbjct: 208 GADLNLVDSLGYNALH 223
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 50.4 bits (119), Expect = 4e-06
Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 3 SACDAGDHYPLHLLVWKNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLL 61
+A D H LHL + + + K LQ + E+VD G+T LH A + G L++ ++L
Sbjct: 80 TAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILC 139
Query: 62 RHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
HK+ + ++ G L AV G E+ + +L H
Sbjct: 140 EHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDH 174
Score = 48.9 bits (115), Expect = 1e-05
Identities = 23/68 (33%), Positives = 36/68 (52%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G + D G+T HLA + GH+E RV++ H DVT ++ G + LH A E
Sbjct: 42 KGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHEC 101
Query: 90 VYTVLQHR 97
+ +LQ +
Sbjct: 102 IRKLLQSK 109
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/83 (32%), Positives = 37/83 (44%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G +V A D G + LHLA H E R LL+ K + G T LH A + G + V
Sbjct: 76 GVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAV 135
Query: 91 YTVLQHRDYHNTSMALEGVPELL 113
+ +H+ N +P LL
Sbjct: 136 QILCEHKSPINLKDLDGNIPLLL 158
Score = 30.8 bits (68), Expect = 3.6
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKEL--QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
D + PL LL +N + ++ L G +V + + GRT L LA +G + L++
Sbjct: 149 DLDGNIPL-LLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 207
Query: 64 KADVTKENRQGWTVLH 79
AD+ + G+ LH
Sbjct: 208 GADLNLVDSLGYNALH 223
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 50.4 bits (119), Expect = 4e-06
Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 3 SACDAGDHYPLHLLVWKNDYRQLEKELQGQ-NVEAVDPRGRTLLHLAVSLGHLESARVLL 61
+A D H LHL + + + K LQ + E+VD G+T LH A + G L++ ++L
Sbjct: 80 TAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILC 139
Query: 62 RHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQH 96
HK+ + ++ G L AV G E+ + +L H
Sbjct: 140 EHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDH 174
Score = 48.9 bits (115), Expect = 1e-05
Identities = 23/68 (33%), Positives = 36/68 (52%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G + D G+T HLA + GH+E RV++ H DVT ++ G + LH A E
Sbjct: 42 KGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHEC 101
Query: 90 VYTVLQHR 97
+ +LQ +
Sbjct: 102 IRKLLQSK 109
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/83 (32%), Positives = 37/83 (44%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G +V A D G + LHLA H E R LL+ K + G T LH A + G + V
Sbjct: 76 GVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAV 135
Query: 91 YTVLQHRDYHNTSMALEGVPELL 113
+ +H+ N +P LL
Sbjct: 136 QILCEHKSPINLKDLDGNIPLLL 158
Score = 30.8 bits (68), Expect = 3.6
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 6 DAGDHYPLHLLVWKNDYRQLEKEL--QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
D + PL LL +N + ++ L G +V + + GRT L LA +G + L++
Sbjct: 149 DLDGNIPL-LLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 207
Query: 64 KADVTKENRQGWTVLH 79
AD+ + G+ LH
Sbjct: 208 GADLNLVDSLGYNALH 223
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 49.7 bits (117), Expect = 8e-06
Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Query: 4 ACDAGDHYPLHLLVWKNDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
AC+ G + LL+ N L + G +A DP G + LHLA GH++ R+LL+
Sbjct: 155 ACEFGRVGVVQLLLSSNMCAALLEPRPG---DATDPNGTSPLHLAAKNGHIDIIRLLLQA 211
Query: 64 KADVTKENRQGWTVLHEAVSTGDPEMVYTVL 94
D+ ++ + G T LHEA G E+V +L
Sbjct: 212 GIDINRQTKSG-TALHEAALCGKTEVVRLLL 241
Score = 37.0 bits (84), Expect = 0.051
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH W+ ++ L+ G V G LHLA GH + + +LL+H+++
Sbjct: 85 PLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMV 144
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVL 94
+ G T L A G +V +L
Sbjct: 145 DNSGKTPLDLACEFGRVGVVQLLL 168
Score = 32.7 bits (73), Expect = 0.96
Identities = 22/63 (34%), Positives = 31/63 (49%)
Query: 33 NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYT 92
NV DP G + LH A G+ E +LL +A V ++ +G LH A G E +
Sbjct: 41 NVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKL 100
Query: 93 VLQ 95
VL+
Sbjct: 101 VLK 103
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 49.3 bits (116), Expect = 1e-05
Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ KN + +E ++ G +++A+ G T +H+A +GHL +LL++ A
Sbjct: 380 PLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT 439
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
N +G T LH A G E+V +L++
Sbjct: 440 NIRGETALHMAARAGQVEVVRCLLRN 465
Score = 46.6 bits (109), Expect = 6e-05
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 11/119 (9%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
P+H+ + + LQ G + + + RG T LH+A G +E R LLR+ A V
Sbjct: 413 PIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDAR 472
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTS----------MALEGVPELLQKILEA 119
R+ T LH A G E+V +LQH + + + A EG ++ +LEA
Sbjct: 473 AREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEA 531
Score = 42.7 bits (99), Expect = 0.001
Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Query: 3 SACDAGDHYPLHLLVWKNDYRQLEKEL--QGQNVEAVDPRGRTLLHLAVSLGHLESARVL 60
+ C+ LHL K + L +EL +G +V++ +G T LH+A G E +VL
Sbjct: 37 NTCNQNGLNALHLAA-KEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVL 95
Query: 61 LRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTS 103
++ A++ +++ G+T L+ A ++V +L++ +T+
Sbjct: 96 VKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTA 138
Score = 40.0 bits (92), Expect = 0.006
Identities = 22/75 (29%), Positives = 38/75 (50%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G + +A G T L +A G+++ LL+ A+V + + G+T LH+A G ++
Sbjct: 697 GADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHII 756
Query: 91 YTVLQHRDYHNTSMA 105
+LQH N + A
Sbjct: 757 NVLLQHGAKPNATTA 771
Score = 37.7 bits (86), Expect = 0.030
Identities = 32/98 (32%), Positives = 40/98 (40%), Gaps = 6/98 (6%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
QG NV A G T LH A GH VLL+H A G T L A G +
Sbjct: 729 QGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISV 788
Query: 90 VYT--VLQHRDYHNTSMALE----GVPELLQKILEAPD 121
V T V+ T+ E VPE + ++L+ D
Sbjct: 789 VDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSD 826
Score = 37.4 bits (85), Expect = 0.039
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Query: 12 PLHLLVWKNDYRQLEKEL-QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ + + ++ L +G ++A G T LH A GH + +LL A +
Sbjct: 248 PLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLAR 307
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQHR 97
+ G + LH A E V +LQH+
Sbjct: 308 TKNGLSPLHMAAQGDHVECVKHLLQHK 334
Score = 37.0 bits (84), Expect = 0.051
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ KN + L G V +G T LHLA GH + +LL A++
Sbjct: 611 PLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMS 670
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
+ G T LH A + + +H
Sbjct: 671 TKSGLTSLHLAAQEDKVNVADILTKH 696
Score = 36.6 bits (83), Expect = 0.066
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Query: 12 PLHLLV-WKNDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ + N L +G + A G T LH+A ++ A LL + A+
Sbjct: 578 PLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIV 637
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVL 94
+QG T LH A G +MV +L
Sbjct: 638 TKQGVTPLHLASQEGHTDMVTLLL 661
Score = 36.2 bits (82), Expect = 0.087
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 32 QNVEAVDPRGR---TLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPE 88
+N VD R R T LH+A LG E ++LL+H A G+T LH + G +
Sbjct: 464 RNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVD 523
Query: 89 MVYTVLQHRDYHN 101
+ +L+ H+
Sbjct: 524 VASVLLEAGAAHS 536
Score = 35.4 bits (80), Expect = 0.15
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 9/91 (9%)
Query: 13 LHLLVWKNDYRQLEKELQGQN---------VEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
LH+ K+D + LQ + V G T LH+A G++ A +LL
Sbjct: 175 LHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 234
Query: 64 KADVTKENRQGWTVLHEAVSTGDPEMVYTVL 94
A V R G T LH A G+ MV +L
Sbjct: 235 GAAVDFTARNGITPLHVASKRGNTNMVKLLL 265
Score = 35.4 bits (80), Expect = 0.15
Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 12 PLHLLVWKNDYRQLEKEL-QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLHL + + L +G N+ G T LHLA + A +L +H AD
Sbjct: 644 PLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAH 703
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQ 95
+ G+T L A G+ +MV +L+
Sbjct: 704 TKLGYTPLIVACHYGNVKMVNFLLK 728
Score = 35.0 bits (79), Expect = 0.19
Identities = 20/63 (31%), Positives = 32/63 (50%)
Query: 35 EAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVL 94
+A G T LH++ G ++ A VLL A + ++G+T LH A G ++ +L
Sbjct: 503 DAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLL 562
Query: 95 QHR 97
Q R
Sbjct: 563 QRR 565
Score = 34.7 bits (78), Expect = 0.25
Identities = 19/65 (29%), Positives = 31/65 (47%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G ++ + G LHLA GH+ + LL + V ++G T LH A G E+V
Sbjct: 33 GIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVV 92
Query: 91 YTVLQ 95
+++
Sbjct: 93 KVLVK 97
Score = 34.7 bits (78), Expect = 0.25
Identities = 18/67 (26%), Positives = 34/67 (50%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G N+ A G T L++A H++ + LL + A+ + G+T L A+ G +
Sbjct: 98 EGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQA 157
Query: 90 VYTVLQH 96
V +L++
Sbjct: 158 VAILLEN 164
Score = 34.7 bits (78), Expect = 0.25
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH + +E L+ G + A G + LH+A H+E + LL+HKA V
Sbjct: 281 PLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDV 340
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPEL 112
T LH A G + +L R N + AL G L
Sbjct: 341 TLDYLTALHVAAHCGHYRVTKLLLDKRANPN-ARALNGFTPL 381
Score = 33.5 bits (75), Expect = 0.56
Identities = 19/66 (28%), Positives = 32/66 (48%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G V+ G T LH+A G+ ++LL + + R G T LH A +G ++
Sbjct: 234 RGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQV 293
Query: 90 VYTVLQ 95
V +L+
Sbjct: 294 VELLLE 299
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 49.3 bits (116), Expect = 1e-05
Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ KN + +E ++ G +++A+ G T +H+A +GHL +LL++ A
Sbjct: 401 PLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT 460
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
N +G T LH A G E+V +L++
Sbjct: 461 NIRGETALHMAARAGQVEVVRCLLRN 486
Score = 46.6 bits (109), Expect = 6e-05
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 11/119 (9%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
P+H+ + + LQ G + + + RG T LH+A G +E R LLR+ A V
Sbjct: 434 PIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDAR 493
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTS----------MALEGVPELLQKILEA 119
R+ T LH A G E+V +LQH + + + A EG ++ +LEA
Sbjct: 494 AREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEA 552
Score = 42.7 bits (99), Expect = 0.001
Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Query: 3 SACDAGDHYPLHLLVWKNDYRQLEKEL--QGQNVEAVDPRGRTLLHLAVSLGHLESARVL 60
+ C+ LHL K + L +EL +G +V++ +G T LH+A G E +VL
Sbjct: 58 NTCNQNGLNALHLAA-KEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVL 116
Query: 61 LRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTS 103
++ A++ +++ G+T L+ A ++V +L++ +T+
Sbjct: 117 VKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTA 159
Score = 40.0 bits (92), Expect = 0.006
Identities = 22/75 (29%), Positives = 38/75 (50%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G + +A G T L +A G+++ LL+ A+V + + G+T LH+A G ++
Sbjct: 718 GADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHII 777
Query: 91 YTVLQHRDYHNTSMA 105
+LQH N + A
Sbjct: 778 NVLLQHGAKPNATTA 792
Score = 37.7 bits (86), Expect = 0.030
Identities = 32/98 (32%), Positives = 40/98 (40%), Gaps = 6/98 (6%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
QG NV A G T LH A GH VLL+H A G T L A G +
Sbjct: 750 QGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISV 809
Query: 90 VYT--VLQHRDYHNTSMALE----GVPELLQKILEAPD 121
V T V+ T+ E VPE + ++L+ D
Sbjct: 810 VDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSD 847
Score = 37.4 bits (85), Expect = 0.039
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Query: 12 PLHLLVWKNDYRQLEKEL-QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ + + ++ L +G ++A G T LH A GH + +LL A +
Sbjct: 269 PLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLAR 328
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQHR 97
+ G + LH A E V +LQH+
Sbjct: 329 TKNGLSPLHMAAQGDHVECVKHLLQHK 355
Score = 37.0 bits (84), Expect = 0.051
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ KN + L G V +G T LHLA GH + +LL A++
Sbjct: 632 PLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMS 691
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
+ G T LH A + + +H
Sbjct: 692 TKSGLTSLHLAAQEDKVNVADILTKH 717
Score = 36.6 bits (83), Expect = 0.066
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Query: 12 PLHLLV-WKNDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ + N L +G + A G T LH+A ++ A LL + A+
Sbjct: 599 PLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIV 658
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVL 94
+QG T LH A G +MV +L
Sbjct: 659 TKQGVTPLHLASQEGHTDMVTLLL 682
Score = 36.2 bits (82), Expect = 0.087
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 32 QNVEAVDPRGR---TLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPE 88
+N VD R R T LH+A LG E ++LL+H A G+T LH + G +
Sbjct: 485 RNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVD 544
Query: 89 MVYTVLQHRDYHN 101
+ +L+ H+
Sbjct: 545 VASVLLEAGAAHS 557
Score = 35.4 bits (80), Expect = 0.15
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 9/91 (9%)
Query: 13 LHLLVWKNDYRQLEKELQGQN---------VEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
LH+ K+D + LQ + V G T LH+A G++ A +LL
Sbjct: 196 LHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 255
Query: 64 KADVTKENRQGWTVLHEAVSTGDPEMVYTVL 94
A V R G T LH A G+ MV +L
Sbjct: 256 GAAVDFTARNGITPLHVASKRGNTNMVKLLL 286
Score = 35.4 bits (80), Expect = 0.15
Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 12 PLHLLVWKNDYRQLEKEL-QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLHL + + L +G N+ G T LHLA + A +L +H AD
Sbjct: 665 PLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAH 724
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQ 95
+ G+T L A G+ +MV +L+
Sbjct: 725 TKLGYTPLIVACHYGNVKMVNFLLK 749
Score = 35.0 bits (79), Expect = 0.19
Identities = 20/63 (31%), Positives = 32/63 (50%)
Query: 35 EAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVL 94
+A G T LH++ G ++ A VLL A + ++G+T LH A G ++ +L
Sbjct: 524 DAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLL 583
Query: 95 QHR 97
Q R
Sbjct: 584 QRR 586
Score = 34.7 bits (78), Expect = 0.25
Identities = 19/65 (29%), Positives = 31/65 (47%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G ++ + G LHLA GH+ + LL + V ++G T LH A G E+V
Sbjct: 54 GIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVV 113
Query: 91 YTVLQ 95
+++
Sbjct: 114 KVLVK 118
Score = 34.7 bits (78), Expect = 0.25
Identities = 18/67 (26%), Positives = 34/67 (50%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G N+ A G T L++A H++ + LL + A+ + G+T L A+ G +
Sbjct: 119 EGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQA 178
Query: 90 VYTVLQH 96
V +L++
Sbjct: 179 VAILLEN 185
Score = 34.7 bits (78), Expect = 0.25
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH + +E L+ G + A G + LH+A H+E + LL+HKA V
Sbjct: 302 PLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDV 361
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPEL 112
T LH A G + +L R N + AL G L
Sbjct: 362 TLDYLTALHVAAHCGHYRVTKLLLDKRANPN-ARALNGFTPL 402
Score = 33.5 bits (75), Expect = 0.56
Identities = 19/66 (28%), Positives = 32/66 (48%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G V+ G T LH+A G+ ++LL + + R G T LH A +G ++
Sbjct: 255 RGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQV 314
Query: 90 VYTVLQ 95
V +L+
Sbjct: 315 VELLLE 320
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 49.3 bits (116), Expect = 1e-05
Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ KN + +E ++ G +++A+ G T +H+A +GHL +LL++ A
Sbjct: 401 PLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT 460
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
N +G T LH A G E+V +L++
Sbjct: 461 NIRGETALHMAARAGQVEVVRCLLRN 486
Score = 46.6 bits (109), Expect = 6e-05
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 11/119 (9%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
P+H+ + + LQ G + + + RG T LH+A G +E R LLR+ A V
Sbjct: 434 PIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDAR 493
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTS----------MALEGVPELLQKILEA 119
R+ T LH A G E+V +LQH + + + A EG ++ +LEA
Sbjct: 494 AREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEA 552
Score = 42.7 bits (99), Expect = 0.001
Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Query: 3 SACDAGDHYPLHLLVWKNDYRQLEKEL--QGQNVEAVDPRGRTLLHLAVSLGHLESARVL 60
+ C+ LHL K + L +EL +G +V++ +G T LH+A G E +VL
Sbjct: 58 NTCNQNGLNALHLAA-KEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVL 116
Query: 61 LRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTS 103
++ A++ +++ G+T L+ A ++V +L++ +T+
Sbjct: 117 VKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTA 159
Score = 40.0 bits (92), Expect = 0.006
Identities = 22/75 (29%), Positives = 38/75 (50%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G + +A G T L +A G+++ LL+ A+V + + G+T LH+A G ++
Sbjct: 718 GADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHII 777
Query: 91 YTVLQHRDYHNTSMA 105
+LQH N + A
Sbjct: 778 NVLLQHGAKPNATTA 792
Score = 37.7 bits (86), Expect = 0.030
Identities = 32/98 (32%), Positives = 40/98 (40%), Gaps = 6/98 (6%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
QG NV A G T LH A GH VLL+H A G T L A G +
Sbjct: 750 QGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISV 809
Query: 90 VYT--VLQHRDYHNTSMALE----GVPELLQKILEAPD 121
V T V+ T+ E VPE + ++L+ D
Sbjct: 810 VDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSD 847
Score = 37.4 bits (85), Expect = 0.039
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Query: 12 PLHLLVWKNDYRQLEKEL-QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ + + ++ L +G ++A G T LH A GH + +LL A +
Sbjct: 269 PLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLAR 328
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQHR 97
+ G + LH A E V +LQH+
Sbjct: 329 TKNGLSPLHMAAQGDHVECVKHLLQHK 355
Score = 37.0 bits (84), Expect = 0.051
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 1/86 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ KN + L G V +G T LHLA GH + +LL A++
Sbjct: 632 PLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMS 691
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQH 96
+ G T LH A + + +H
Sbjct: 692 TKSGLTSLHLAAQEDKVNVADILTKH 717
Score = 36.6 bits (83), Expect = 0.066
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Query: 12 PLHLLV-WKNDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH+ + N L +G + A G T LH+A ++ A LL + A+
Sbjct: 599 PLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIV 658
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVL 94
+QG T LH A G +MV +L
Sbjct: 659 TKQGVTPLHLASQEGHTDMVTLLL 682
Score = 36.2 bits (82), Expect = 0.087
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 32 QNVEAVDPRGR---TLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPE 88
+N VD R R T LH+A LG E ++LL+H A G+T LH + G +
Sbjct: 485 RNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVD 544
Query: 89 MVYTVLQHRDYHN 101
+ +L+ H+
Sbjct: 545 VASVLLEAGAAHS 557
Score = 35.4 bits (80), Expect = 0.15
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 9/91 (9%)
Query: 13 LHLLVWKNDYRQLEKELQGQN---------VEAVDPRGRTLLHLAVSLGHLESARVLLRH 63
LH+ K+D + LQ + V G T LH+A G++ A +LL
Sbjct: 196 LHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 255
Query: 64 KADVTKENRQGWTVLHEAVSTGDPEMVYTVL 94
A V R G T LH A G+ MV +L
Sbjct: 256 GAAVDFTARNGITPLHVASKRGNTNMVKLLL 286
Score = 35.4 bits (80), Expect = 0.15
Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 12 PLHLLVWKNDYRQLEKEL-QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLHL + + L +G N+ G T LHLA + A +L +H AD
Sbjct: 665 PLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAH 724
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQ 95
+ G+T L A G+ +MV +L+
Sbjct: 725 TKLGYTPLIVACHYGNVKMVNFLLK 749
Score = 35.0 bits (79), Expect = 0.19
Identities = 20/63 (31%), Positives = 32/63 (50%)
Query: 35 EAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVL 94
+A G T LH++ G ++ A VLL A + ++G+T LH A G ++ +L
Sbjct: 524 DAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLL 583
Query: 95 QHR 97
Q R
Sbjct: 584 QRR 586
Score = 34.7 bits (78), Expect = 0.25
Identities = 19/65 (29%), Positives = 31/65 (47%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G ++ + G LHLA GH+ + LL + V ++G T LH A G E+V
Sbjct: 54 GIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVV 113
Query: 91 YTVLQ 95
+++
Sbjct: 114 KVLVK 118
Score = 34.7 bits (78), Expect = 0.25
Identities = 18/67 (26%), Positives = 34/67 (50%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G N+ A G T L++A H++ + LL + A+ + G+T L A+ G +
Sbjct: 119 EGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQA 178
Query: 90 VYTVLQH 96
V +L++
Sbjct: 179 VAILLEN 185
Score = 34.7 bits (78), Expect = 0.25
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 12 PLHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKE 70
PLH + +E L+ G + A G + LH+A H+E + LL+HKA V
Sbjct: 302 PLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDV 361
Query: 71 NRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPEL 112
T LH A G + +L R N + AL G L
Sbjct: 362 TLDYLTALHVAAHCGHYRVTKLLLDKRANPN-ARALNGFTPL 402
Score = 33.5 bits (75), Expect = 0.56
Identities = 19/66 (28%), Positives = 32/66 (48%)
Query: 30 QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEM 89
+G V+ G T LH+A G+ ++LL + + R G T LH A +G ++
Sbjct: 255 RGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQV 314
Query: 90 VYTVLQ 95
V +L+
Sbjct: 315 VELLLE 320
>gi|7705748 TNNI3 interacting kinase isoform b [Homo sapiens]
Length = 835
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Query: 13 LHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKEN 71
LHL V+K++ + L G +++ V G T LH+A GHLE+A VLL+H A+V ++
Sbjct: 105 LHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQD 164
Query: 72 RQGWTVLHEAVSTGDPEMVYTVLQ 95
+T LH A G ++ +L+
Sbjct: 165 AVFFTPLHIAAYYGHEQVTRLLLK 188
Score = 36.2 bits (82), Expect = 0.087
Identities = 24/68 (35%), Positives = 30/68 (44%)
Query: 29 LQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPE 88
L+G + G T LHLAV + E LL AD+ + G T LH A G E
Sbjct: 89 LKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLE 148
Query: 89 MVYTVLQH 96
+LQH
Sbjct: 149 AADVLLQH 156
Score = 33.5 bits (75), Expect = 0.56
Identities = 21/55 (38%), Positives = 26/55 (47%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTG 85
G NV D T LH+A GH + R+LL+ ADV G LH A + G
Sbjct: 157 GANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKG 211
Score = 30.8 bits (68), Expect = 3.6
Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)
Query: 6 DAGDHYPLHLLVWK---NDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLR 62
+ GD PLHL K N + L +E +V A D LH GH + + LL+
Sbjct: 198 EVGDR-PLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQ 256
Query: 63 HKADVTKE--NRQGWTVLHEAVSTGDPEMVYTVLQ 95
+V N G T LH A G E+ ++Q
Sbjct: 257 SDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQ 291
>gi|163914396 TNNI3 interacting kinase isoform a [Homo sapiens]
Length = 936
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Query: 13 LHLLVWKNDYRQLEKELQ-GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKEN 71
LHL V+K++ + L G +++ V G T LH+A GHLE+A VLL+H A+V ++
Sbjct: 206 LHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQD 265
Query: 72 RQGWTVLHEAVSTGDPEMVYTVLQ 95
+T LH A G ++ +L+
Sbjct: 266 AVFFTPLHIAAYYGHEQVTRLLLK 289
Score = 36.2 bits (82), Expect = 0.087
Identities = 24/68 (35%), Positives = 30/68 (44%)
Query: 29 LQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPE 88
L+G + G T LHLAV + E LL AD+ + G T LH A G E
Sbjct: 190 LKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLE 249
Query: 89 MVYTVLQH 96
+LQH
Sbjct: 250 AADVLLQH 257
Score = 33.5 bits (75), Expect = 0.56
Identities = 21/55 (38%), Positives = 26/55 (47%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTG 85
G NV D T LH+A GH + R+LL+ ADV G LH A + G
Sbjct: 258 GANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKG 312
Score = 30.8 bits (68), Expect = 3.6
Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)
Query: 6 DAGDHYPLHLLVWK---NDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLR 62
+ GD PLHL K N + L +E +V A D LH GH + + LL+
Sbjct: 299 EVGDR-PLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQ 357
Query: 63 HKADVTKE--NRQGWTVLHEAVSTGDPEMVYTVLQ 95
+V N G T LH A G E+ ++Q
Sbjct: 358 SDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQ 392
>gi|14249672 protein phosphatase 1, regulatory (inhibitor) subunit
16A [Homo sapiens]
Length = 528
Score = 49.3 bits (116), Expect = 1e-05
Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Query: 31 GQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMV 90
G ++ A G TLLH+A + G E+A +LL H+A ++ +++ GW LH A G +V
Sbjct: 222 GADLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAAAYWGQVPLV 281
Query: 91 YTVLQHRDYHNTSMALEGVP-------ELLQKILE 118
++ H N ++ P E+ K+LE
Sbjct: 282 ELLVAHGADLNAKSLMDETPLDVCGDEEVRAKLLE 316
Score = 33.5 bits (75), Expect = 0.56
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 20 NDYRQLEKEL--QGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQG 74
+D+R++ ++L G N+ A D T LH A + GHL +L+ A++ N G
Sbjct: 114 DDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDG 170
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,359,133
Number of Sequences: 37866
Number of extensions: 898278
Number of successful extensions: 4289
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 258
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 3033
Number of HSP's gapped (non-prelim): 1247
length of query: 590
length of database: 18,247,518
effective HSP length: 108
effective length of query: 482
effective length of database: 14,157,990
effective search space: 6824151180
effective search space used: 6824151180
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.