Guide to the Human Genome
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Search of human proteins with 38569477

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38569477 metaxin 1 isoform 2 [Homo sapiens]
         (435 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38569477 metaxin 1 isoform 2 [Homo sapiens]                        897   0.0  
gi|38569475 metaxin 1 isoform 1 [Homo sapiens]                        880   0.0  
gi|148806867 metaxin 3 [Homo sapiens]                                 221   1e-57
gi|5729937 metaxin 2 [Homo sapiens]                                    77   4e-14
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]            43   5e-04
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...    42   0.001
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...    42   0.001
gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo sa...    40   0.003
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s...    40   0.004
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s...    40   0.004
gi|169164483 PREDICTED: hypothetical protein [Homo sapiens]            40   0.005
gi|113414226 PREDICTED: hypothetical protein [Homo sapiens]            40   0.005
gi|113413437 PREDICTED: hypothetical protein [Homo sapiens]            40   0.005
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]             40   0.005
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]             40   0.005
gi|24308336 hypothetical protein LOC84553 [Homo sapiens]               39   0.009
gi|239754987 PREDICTED: hypothetical protein [Homo sapiens]            39   0.012
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    39   0.012
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     39   0.012
gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo sa...    39   0.012
gi|239755142 PREDICTED: hypothetical protein [Homo sapiens]            38   0.016
gi|239749631 PREDICTED: hypothetical protein [Homo sapiens]            38   0.016
gi|239743906 PREDICTED: hypothetical protein XP_002342988 [Homo ...    38   0.016
gi|38787970 tensin like C1 domain containing phosphatase isoform...    38   0.016
gi|38787957 tensin like C1 domain containing phosphatase isoform...    38   0.016
gi|38787941 tensin like C1 domain containing phosphatase isoform...    38   0.016
gi|188536004 zinc finger protein 469 [Homo sapiens]                    38   0.021
gi|224465238 hypothetical protein LOC283999 [Homo sapiens]             37   0.027
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]       37   0.027
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       37   0.027

>gi|38569477 metaxin 1 isoform 2 [Homo sapiens]
          Length = 435

 Score =  897 bits (2317), Expect = 0.0
 Identities = 435/435 (100%), Positives = 435/435 (100%)

Query: 1   MLLGGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRR 60
           MLLGGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRR
Sbjct: 1   MLLGGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRR 60

Query: 61  RDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTAT 120
           RDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTAT
Sbjct: 61  RDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTAT 120

Query: 121 IGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYAR 180
           IGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYAR
Sbjct: 121 IGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYAR 180

Query: 181 FTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEVHTFWIDTKNYVEV 240
           FTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEVHTFWIDTKNYVEV
Sbjct: 181 FTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEVHTFWIDTKNYVEV 240

Query: 241 TRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLTGEHRPEDEEELEKELYREARECLTLLS 300
           TRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLTGEHRPEDEEELEKELYREARECLTLLS
Sbjct: 241 TRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLTGEHRPEDEEELEKELYREARECLTLLS 300

Query: 301 QRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSLYF 360
           QRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSLYF
Sbjct: 301 QRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSLYF 360

Query: 361 PWDGAEVPPQRQTPAGPETEEEPYRRRNQILSVLAGLAAMVGYALLSGIVSIQRATPARA 420
           PWDGAEVPPQRQTPAGPETEEEPYRRRNQILSVLAGLAAMVGYALLSGIVSIQRATPARA
Sbjct: 361 PWDGAEVPPQRQTPAGPETEEEPYRRRNQILSVLAGLAAMVGYALLSGIVSIQRATPARA 420

Query: 421 PGTRTLGMAEEDEEE 435
           PGTRTLGMAEEDEEE
Sbjct: 421 PGTRTLGMAEEDEEE 435


>gi|38569475 metaxin 1 isoform 1 [Homo sapiens]
          Length = 466

 Score =  880 bits (2275), Expect = 0.0
 Identities = 435/466 (93%), Positives = 435/466 (93%), Gaps = 31/466 (6%)

Query: 1   MLLGGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRR 60
           MLLGGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRR
Sbjct: 1   MLLGGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRR 60

Query: 61  RDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTAT 120
           RDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTAT
Sbjct: 61  RDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTAT 120

Query: 121 IGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYAR 180
           IGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYAR
Sbjct: 121 IGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYAR 180

Query: 181 FTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKE-------------- 226
           FTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKE              
Sbjct: 181 FTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEKYNADYDLSARQGA 240

Query: 227 -----------------VHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERL 269
                            VHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERL
Sbjct: 241 DTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERL 300

Query: 270 QLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLL 329
           QLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLL
Sbjct: 301 QLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLL 360

Query: 330 QAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVPPQRQTPAGPETEEEPYRRRNQ 389
           QAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVPPQRQTPAGPETEEEPYRRRNQ
Sbjct: 361 QAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVPPQRQTPAGPETEEEPYRRRNQ 420

Query: 390 ILSVLAGLAAMVGYALLSGIVSIQRATPARAPGTRTLGMAEEDEEE 435
           ILSVLAGLAAMVGYALLSGIVSIQRATPARAPGTRTLGMAEEDEEE
Sbjct: 421 ILSVLAGLAAMVGYALLSGIVSIQRATPARAPGTRTLGMAEEDEEE 466


>gi|148806867 metaxin 3 [Homo sapiens]
          Length = 312

 Score =  221 bits (562), Expect = 1e-57
 Identities = 113/274 (41%), Positives = 163/274 (59%), Gaps = 37/274 (13%)

Query: 150 MAAPMELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKISNPWQSPSGTLPALRTSH 209
           MAAP+EL CW GGWGLPSV  +SL V+ YA+F+GAPLKV+ I N W+   G +P L T+ 
Sbjct: 1   MAAPLELSCWGGGWGLPSVHSESLVVMAYAKFSGAPLKVNVIDNTWRGSRGDVPIL-TTE 59

Query: 210 GEVISVPHKIITHLRKE-------------------------------VHTFWIDTKNYV 238
            +++S P KI+  LRK+                               +HTFW+++ NY 
Sbjct: 60  DDMVSQPAKILNFLRKQKYNADYELSAKQGADTLAYIALLEEKLLPAVLHTFWVESDNYF 119

Query: 239 EVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLTGEHRPEDEEELEKELYREARECLTL 298
            VT+ W+A  +PFPL+  LPGRM +  + R+ L  G+       E+E ++YR+A+ECL L
Sbjct: 120 TVTKPWFASQIPFPLSLILPGRMSKGALNRILLTRGQPPLYHLREVEAQIYRDAKECLNL 179

Query: 299 LSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSL 358
           LS RLG+ +FFFGD P++LDA+VF +LA L + + P  +LQ HL+ L NLC +C  ILS 
Sbjct: 180 LSNRLGTSQFFFGDTPSTLDAYVFGFLAPLYKVRFPKVQLQEHLKQLSNLCRFCDDILSS 239

Query: 359 YFPWDGAEVPPQRQTPAGPETEEEPYRRRNQILS 392
           YF      +     +PAG ET +   ++  Q+++
Sbjct: 240 YFRLSLGGI-----SPAGQETVDANLQKLTQLVN 268


>gi|5729937 metaxin 2 [Homo sapiens]
          Length = 263

 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 56/221 (25%), Positives = 94/221 (42%), Gaps = 39/221 (17%)

Query: 172 SLAVLTYARFTGAPLKVHKISNP-WQSPSGTLPALRTSHGEVISVPHKIITHLRKEVHTF 230
           SLAV  + +    P+KV   +N  + SPSG +P +   + +V+S    I+  ++ + H+ 
Sbjct: 41  SLAVQAFLQMCNLPIKVVCRANAEYMSPSGKVPFIHVGN-QVVSELGPIVQFVKAKGHSL 99

Query: 231 -------------------------------WIDTKNYVEVTRKWYAEAMPFPLNFFLPG 259
                                          W D     E+T   Y    P+PLN  L  
Sbjct: 100 SDGLEEVQKAEMKAYMELVNNMLLTAELYLQWCDEATVGEITHARYGSPYPWPLNHILAY 159

Query: 260 RMQRQYMERLQLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDA 319
           + Q +   +++ +    +  D+      +  +  +C   LSQRLG+Q +FF   P  LDA
Sbjct: 160 QKQWEVKRKMKAIGWGKKTLDQ------VLEDVDQCCQALSQRLGTQPYFFNKQPTELDA 213

Query: 320 FVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSLYF 360
            VF +L  +L  +L + +L   ++   NL A+C  I   YF
Sbjct: 214 LVFGHLYTILTTQLTNDELSEKVKNYSNLLAFCRRIEQHYF 254


>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
          Length = 724

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 26/93 (27%), Positives = 50/93 (53%), Gaps = 3/93 (3%)

Query: 195 WQSPSGTLPALRTSHGEVISVPHKIITHLRKEVHTFWIDTKNYVEVTRKWYAEAMPFPLN 254
           W+S +G    +R  HGE I    K+I HL KE  T +++ +   EV +K +++ + +P+ 
Sbjct: 157 WESSAGGSFTVRADHGEPIGRGTKVILHL-KEDQTEYLEERRVKEVVKK-HSQFIGYPIT 214

Query: 255 FFLPGRMQRQYM-ERLQLLTGEHRPEDEEELEK 286
            +L    +++   +  +   GE   ED+++ EK
Sbjct: 215 LYLEKEREKEISDDEAEEEKGEKEEEDKDDEEK 247


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 48/147 (32%), Positives = 63/147 (42%), Gaps = 29/147 (19%)

Query: 3   LGGPPRSPRSGT---SPKGPWSSTGHVQFGKSPQ-TW-----PRRTRPRSPEPAAPSGVR 53
           LG P  SPR+     +P+ PWS  G    G+ P+ +W     P  T P SP PA+P G R
Sbjct: 274 LGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPT-PASPRPASPCGKR 332

Query: 54  GSTWTRRRDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGIS 113
             +      TP  A P ALSR       G  PP P    P+P           LA    S
Sbjct: 333 RYS---SSGTPSSASP-ALSRRGSLGEEGSEPPPPP---PLP-----------LARDPGS 374

Query: 114 PGPLTATIGGAVAGGGPRQGRAEAHKE 140
           PGP    +G   A   P++ R  + ++
Sbjct: 375 PGPFD-YVGAPPAESIPQKTRRTSSEQ 400


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 48/147 (32%), Positives = 63/147 (42%), Gaps = 29/147 (19%)

Query: 3   LGGPPRSPRSGT---SPKGPWSSTGHVQFGKSPQ-TW-----PRRTRPRSPEPAAPSGVR 53
           LG P  SPR+     +P+ PWS  G    G+ P+ +W     P  T P SP PA+P G R
Sbjct: 211 LGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPT-PASPRPASPCGKR 269

Query: 54  GSTWTRRRDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGIS 113
             +      TP  A P ALSR       G  PP P    P+P           LA    S
Sbjct: 270 RYS---SSGTPSSASP-ALSRRGSLGEEGSEPPPPP---PLP-----------LARDPGS 311

Query: 114 PGPLTATIGGAVAGGGPRQGRAEAHKE 140
           PGP    +G   A   P++ R  + ++
Sbjct: 312 PGPFD-YVGAPPAESIPQKTRRTSSEQ 337


>gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo
           sapiens]
          Length = 1067

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 47/173 (27%), Positives = 70/173 (40%), Gaps = 22/173 (12%)

Query: 44  PEPAAPSGVRGSTWTRRRDT-----PRRAGPTALSRYVGH--LWMGRRPPSPEARGPVPR 96
           P P + S  R S  TR   +     P +  P     Y G+  LW   R P P  RGP PR
Sbjct: 97  PTPGSGSRSRFSHRTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWP-YRAPMPRKRGPPPR 155

Query: 97  SSAASRARRSLASPGISPGPLTATIGGAVAGGGPRQGRAEAHKEVFPGQRVG---KMAAP 153
             A+   +R+      +P  L  ++G  + G  P     + +  + P +  G   K A P
Sbjct: 156 HWASPPHKRA------TPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAVP 209

Query: 154 MELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKISNPWQSPSGTLPALR 206
                  GG G+P     + AV     ++G   +V +   P + P   +PALR
Sbjct: 210 RSSLARIGGSGMPG---KAPAVWGQDGYSGP--RVREPLPPCRDPGDFVPALR 257


>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
           sapiens]
          Length = 732

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 25/93 (26%), Positives = 48/93 (51%), Gaps = 6/93 (6%)

Query: 195 WQSPSGTLPALRTSHGEVISVPHKIITHLRKEVHTFWIDTKNYVEVTRKWYAEAMPFPLN 254
           W+S +G    +RT  GE +    K+I HL KE  T +++ +   E+ +K +++ + +P+ 
Sbjct: 162 WESSAGGSFTVRTDTGEPMGRGTKVILHL-KEDQTEYLEERRIKEIVKK-HSQFIGYPIT 219

Query: 255 FFLPGRMQRQYMERLQLLTGEHRPEDEEELEKE 287
            F+     ++  +       E + + EEE EKE
Sbjct: 220 LFVEKERDKEVSDD----EAEEKEDKEEEKEKE 248


>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
           sapiens]
          Length = 854

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 25/93 (26%), Positives = 48/93 (51%), Gaps = 6/93 (6%)

Query: 195 WQSPSGTLPALRTSHGEVISVPHKIITHLRKEVHTFWIDTKNYVEVTRKWYAEAMPFPLN 254
           W+S +G    +RT  GE +    K+I HL KE  T +++ +   E+ +K +++ + +P+ 
Sbjct: 284 WESSAGGSFTVRTDTGEPMGRGTKVILHL-KEDQTEYLEERRIKEIVKK-HSQFIGYPIT 341

Query: 255 FFLPGRMQRQYMERLQLLTGEHRPEDEEELEKE 287
            F+     ++  +       E + + EEE EKE
Sbjct: 342 LFVEKERDKEVSDD----EAEEKEDKEEEKEKE 370


>gi|169164483 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 324

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 47/147 (31%), Positives = 58/147 (39%), Gaps = 27/147 (18%)

Query: 4   GGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAA---------PSGVR- 53
           GGP   PR   S  GP  +    Q  + P   PR TR  +  P           P+G R 
Sbjct: 144 GGPGLPPRGKAS--GP--ARDSAQQRRRPTRRPRGTRGGARRPGVRGQGAAAVGPTGPRP 199

Query: 54  -GSTWTRRRDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGI 112
            G+  +RR   P    P   S + G  W   RPPSP A  P         A R  AS   
Sbjct: 200 TGAPPSRRTPPPGPRRPLR-SPHSGSGWTPARPPSPPAGAP--------EALRPPASTTR 250

Query: 113 SPGPLTATI---GGAVAGGGPRQGRAE 136
           +P PLT +    G A AG  P   ++E
Sbjct: 251 APAPLTLSFSARGLAWAGESPASHQSE 277


>gi|113414226 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 324

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 47/147 (31%), Positives = 58/147 (39%), Gaps = 27/147 (18%)

Query: 4   GGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAA---------PSGVR- 53
           GGP   PR   S  GP  +    Q  + P   PR TR  +  P           P+G R 
Sbjct: 144 GGPGLPPRGKAS--GP--ARDSAQQRRRPTRRPRGTRGGARRPGVRGQGAAAVGPTGPRP 199

Query: 54  -GSTWTRRRDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGI 112
            G+  +RR   P    P   S + G  W   RPPSP A  P         A R  AS   
Sbjct: 200 TGAPPSRRTPPPGPRRPLR-SPHSGSGWTPARPPSPPAGAP--------EALRPPASTTR 250

Query: 113 SPGPLTATI---GGAVAGGGPRQGRAE 136
           +P PLT +    G A AG  P   ++E
Sbjct: 251 APAPLTLSFSARGLAWAGESPASHQSE 277


>gi|113413437 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 324

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 47/147 (31%), Positives = 58/147 (39%), Gaps = 27/147 (18%)

Query: 4   GGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAA---------PSGVR- 53
           GGP   PR   S  GP  +    Q  + P   PR TR  +  P           P+G R 
Sbjct: 144 GGPGLPPRGKAS--GP--ARDSAQQRRRPTRRPRGTRGGARRPGVRGQGAAAVGPTGPRP 199

Query: 54  -GSTWTRRRDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGI 112
            G+  +RR   P    P   S + G  W   RPPSP A  P         A R  AS   
Sbjct: 200 TGAPPSRRTPPPGPRRPLR-SPHSGSGWTPARPPSPPAGAP--------EALRPPASTTR 250

Query: 113 SPGPLTATI---GGAVAGGGPRQGRAE 136
           +P PLT +    G A AG  P   ++E
Sbjct: 251 APAPLTLSFSARGLAWAGESPASHQSE 277


>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
          Length = 475

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 36/141 (25%), Positives = 52/141 (36%), Gaps = 26/141 (18%)

Query: 6   PPRSPRSGTSPKGPWSSTGHVQFGKSPQ----TWPRRTRPRSP--------------EPA 47
           P +  +S + P G  ++T  ++    P+      P  T P+SP              EP+
Sbjct: 259 PAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPS 318

Query: 48  APSGVRGSTWTRRRDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSL 107
           A  G    +W  +   P  A P   S   G          P A    P  +AAS A  S 
Sbjct: 319 AAEGTFAVSWPSQTAEPGPAQPAEASEVAG-------GTQPAAGAQEPGETAASEAASS- 370

Query: 108 ASPGISPGPLTATIGGAVAGG 128
           + P +      AT+ G V GG
Sbjct: 371 SLPAVVVETFPATVNGTVEGG 391


>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
          Length = 506

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 36/141 (25%), Positives = 52/141 (36%), Gaps = 26/141 (18%)

Query: 6   PPRSPRSGTSPKGPWSSTGHVQFGKSPQ----TWPRRTRPRSP--------------EPA 47
           P +  +S + P G  ++T  ++    P+      P  T P+SP              EP+
Sbjct: 290 PAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPS 349

Query: 48  APSGVRGSTWTRRRDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSL 107
           A  G    +W  +   P  A P   S   G          P A    P  +AAS A  S 
Sbjct: 350 AAEGTFAVSWPSQTAEPGPAQPAEASEVAG-------GTQPAAGAQEPGETAASEAASS- 401

Query: 108 ASPGISPGPLTATIGGAVAGG 128
           + P +      AT+ G V GG
Sbjct: 402 SLPAVVVETFPATVNGTVEGG 422


>gi|24308336 hypothetical protein LOC84553 [Homo sapiens]
          Length = 409

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 2/78 (2%)

Query: 285 EKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRG 344
           E+E+Y    + +  L+  LG +K+  G   ++LDA VF +LA  +   LP  + +  ++G
Sbjct: 256 EEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAMWT-LPGTRPERLIKG 314

Query: 345 -LHNLCAYCTHILSLYFP 361
            L NL  YC  I   ++P
Sbjct: 315 ELINLAMYCERIRRKFWP 332


>gi|239754987 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 412

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 44/147 (29%), Positives = 56/147 (38%), Gaps = 33/147 (22%)

Query: 45  EPAAPS-GVRGSTWTRRRDTPRRAGPTALSRYVGHLWMGRRP----PSPEAR---GPVPR 96
           EPA P+ G R S  TR R T  RA   +           RRP    P P  R   G + R
Sbjct: 93  EPARPAEGARPSPGTRARKTRPRARTAST----------RRPCALCPEPALRAQLGRLDR 142

Query: 97  SSAASRARRSLAS---------PGISPGPLTATIGGAVAGGGPRQG------RAEAHKEV 141
                R +R+LA          P +SP P     G A A  GPR+G        ++  E 
Sbjct: 143 RGPQHRVQRALALSAGLEDAHLPCLSPRPSQEMRGEATAREGPREGAPTGCPEGKSCGER 202

Query: 142 FPGQRVGKMAAPMELFCWSGGWGLPSV 168
            PG    +   P  L  W   W  P++
Sbjct: 203 RPGPGTNQPLWPASLSPWRPYWEFPAL 229


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 49/167 (29%), Positives = 57/167 (34%), Gaps = 37/167 (22%)

Query: 6    PPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPA--------APSGVRGSTW 57
            P   P SG   K  W      Q    P   P   +PR  EPA        AP G  G+  
Sbjct: 1152 PGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGA-- 1209

Query: 58   TRRRDTPRRAGPTALSRYVGHLWMGRRPPSPEARGP-VPR----------SSAASRARRS 106
                   R  G TALS           PP PE +GP +PR          +S   +AR S
Sbjct: 1210 ----PDSRAGGDTALSG-------DGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLS 1258

Query: 107  LASPGISPGPLTATIGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAP 153
              S  + P  LT        G GPR+   E       G   G   AP
Sbjct: 1259 RLSLALPPLTLT-----PFPGPGPRRPPWEGADAGAAGGEAGGAGAP 1300



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 2/55 (3%)

Query: 81  MGRRPPSPEARGPVPRSSAASRARRSLASPGISPGP--LTATIGGAVAGGGPRQG 133
           MG   P    RGP P         R+ A P  SP P    A+ G  ++  GP+ G
Sbjct: 766 MGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPG 820


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 43/137 (31%), Positives = 56/137 (40%), Gaps = 14/137 (10%)

Query: 5   GPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDTP 64
           GPP  P+ G  P+GP    G  Q G  PQ   +    RSP P  P G       + +  P
Sbjct: 265 GPP--PQGGNKPQGP-PPPGKPQ-GPPPQGGSKSRSSRSP-PGKPQGPPPQGGNQPQGPP 319

Query: 65  RRAG-PTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTATIGG 123
              G P       G+   G  PP  + +GP P+  + SR+ RS   PG   GP       
Sbjct: 320 PPPGKPQGPPPQGGNKPQGPPPPG-KPQGPPPQGGSKSRSARS--PPGKPQGPPQQEGNN 376

Query: 124 -----AVAGGGPRQGRA 135
                  AGG P+Q +A
Sbjct: 377 PQGPPPPAGGNPQQPQA 393



 Score = 36.2 bits (82), Expect = 0.060
 Identities = 39/113 (34%), Positives = 49/113 (43%), Gaps = 10/113 (8%)

Query: 5   GPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDTP 64
           GPP  P+ G  P+GP    G  Q G  PQ    R+ PRSP P  P G       + +  P
Sbjct: 80  GPP--PQGGNKPQGP-PPPGKPQ-GPPPQGDKSRS-PRSP-PGKPQGPPPQGGNQPQGPP 133

Query: 65  RRAG-PTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGP 116
              G P       G+   G  PP  + +GP P+    SR+ RS   PG   GP
Sbjct: 134 PPPGKPQGPPPQGGNKPQGPPPPG-KPQGPPPQGDNKSRSSRS--PPGKPQGP 183



 Score = 36.2 bits (82), Expect = 0.060
 Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 9/113 (7%)

Query: 5   GPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDTP 64
           GPP  P+ G  P+GP    G  Q G  PQ   +    RSP P  P G       + +  P
Sbjct: 203 GPP--PQGGNKPQGP-PPPGKPQ-GPPPQGDNKSQSARSP-PGKPQGPPPQGGNQPQGPP 257

Query: 65  RRAG-PTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGP 116
              G P       G+   G  PP  + +GP P+  + SR+ RS   PG   GP
Sbjct: 258 PPPGKPQGPPPQGGNKPQGPPPPG-KPQGPPPQGGSKSRSSRS--PPGKPQGP 307


>gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo
           sapiens]
          Length = 685

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 42/232 (18%)

Query: 87  SPEARGPVPRSSAA-SRARRSLASPGISPGPLTATIGGAVAGGGPR--QGRAEAHKEVFP 143
           SP  R P   SS+A  +    +A P +S GP+     G+ + G  R   G  +   +  P
Sbjct: 365 SPGVRQPGSSSSSAPGQPSTGVARPTVSSGPVPRRQNGSSSSGPERSISGSKKPTNDSNP 424

Query: 144 GQR-VGKMAAPMELFCWSGGWGLP-SVDLDSLAVLTYARFTGAPLKV------------- 188
            +R V     P +    SGG G P S  + S   L  +R  G P+               
Sbjct: 425 SRRTVSGTCGPGQPASSSGGPGRPISGSVSSARPLGSSRGPGRPVSSPHELRRPVSGLGP 484

Query: 189 --HKISNPWQSPSGTLPALRTSHGEVISVPHKIITHL---------------RKEVHTFW 231
               +S P +S SG++PA RT      SVP + ++ L               +  V +  
Sbjct: 485 PGRSVSGPGRSISGSIPAGRTVSN---SVPGRPVSSLGPGQTVSSSGPTIKPKCTVVSET 541

Query: 232 IDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLTGEHRPEDEEE 283
           I +KN +  +       M  PL+    G    Q  +RL   TG  R  + EE
Sbjct: 542 ISSKNIISRSSNGQMNGMKPPLS----GYRAAQGPQRLPFPTGYKRQREYEE 589


>gi|239755142 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 219

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 30/84 (35%), Positives = 34/84 (40%), Gaps = 8/84 (9%)

Query: 81  MGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTATIGGAVAGGGPRQG-RAEAHK 139
           M   P SP  +   PR       R  L S G   G L A  GGAV GGG R G RAE  +
Sbjct: 1   MSMFPSSPLFKLNFPRRGRRGERRPGLRSEGRRKGLLAAEAGGAVLGGGRRAGRRAEPPE 60

Query: 140 EVFPGQRVGKMAAPMELFCWSGGW 163
             +  +R   M          GGW
Sbjct: 61  PSYSRERRETMEG-------KGGW 77


>gi|239749631 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 217

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 30/84 (35%), Positives = 34/84 (40%), Gaps = 8/84 (9%)

Query: 81  MGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTATIGGAVAGGGPRQG-RAEAHK 139
           M   P SP  +   PR       R  L S G   G L A  GGAV GGG R G RAE  +
Sbjct: 1   MSMFPSSPLFKLNFPRRGRRGERRPGLRSEGRRKGLLAAEAGGAVLGGGRRAGRRAEPPE 60

Query: 140 EVFPGQRVGKMAAPMELFCWSGGW 163
             +  +R   M          GGW
Sbjct: 61  PSYSRERRETMEG-------KGGW 77


>gi|239743906 PREDICTED: hypothetical protein XP_002342988 [Homo
           sapiens]
          Length = 217

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 30/84 (35%), Positives = 34/84 (40%), Gaps = 8/84 (9%)

Query: 81  MGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTATIGGAVAGGGPRQG-RAEAHK 139
           M   P SP  +   PR       R  L S G   G L A  GGAV GGG R G RAE  +
Sbjct: 1   MSMFPSSPLFKLNFPRRGRRGERRPGLRSEGRRKGLLAAEAGGAVLGGGRRAGRRAEPPE 60

Query: 140 EVFPGQRVGKMAAPMELFCWSGGW 163
             +  +R   M          GGW
Sbjct: 61  PSYSRERRETMEG-------KGGW 77


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
           [Homo sapiens]
          Length = 1285

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 34/125 (27%), Positives = 45/125 (36%), Gaps = 14/125 (11%)

Query: 5   GPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDTP 64
           GP     S  SP  P SS       +SP        PRSP P    G+R + W   R  P
Sbjct: 841 GPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPP 900

Query: 65  RRAGPTALSRYVGHL-WMGRRPPSPEARGPVPRSSAASR------------ARRSLASPG 111
                + L+     + W+   P  P++  P P    A+              +R L  PG
Sbjct: 901 DSPDGSPLTPVPSQMPWLVASPEPPQS-SPTPAFPLAASYDTNGLSQPPLPEKRHLPGPG 959

Query: 112 ISPGP 116
             PGP
Sbjct: 960 QQPGP 964


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
            [Homo sapiens]
          Length = 1409

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 34/125 (27%), Positives = 45/125 (36%), Gaps = 14/125 (11%)

Query: 5    GPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDTP 64
            GP     S  SP  P SS       +SP        PRSP P    G+R + W   R  P
Sbjct: 965  GPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPP 1024

Query: 65   RRAGPTALSRYVGHL-WMGRRPPSPEARGPVPRSSAASR------------ARRSLASPG 111
                 + L+     + W+   P  P++  P P    A+              +R L  PG
Sbjct: 1025 DSPDGSPLTPVPSQMPWLVASPEPPQS-SPTPAFPLAASYDTNGLSQPPLPEKRHLPGPG 1083

Query: 112  ISPGP 116
              PGP
Sbjct: 1084 QQPGP 1088


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
            [Homo sapiens]
          Length = 1419

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 34/125 (27%), Positives = 45/125 (36%), Gaps = 14/125 (11%)

Query: 5    GPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDTP 64
            GP     S  SP  P SS       +SP        PRSP P    G+R + W   R  P
Sbjct: 975  GPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPP 1034

Query: 65   RRAGPTALSRYVGHL-WMGRRPPSPEARGPVPRSSAASR------------ARRSLASPG 111
                 + L+     + W+   P  P++  P P    A+              +R L  PG
Sbjct: 1035 DSPDGSPLTPVPSQMPWLVASPEPPQS-SPTPAFPLAASYDTNGLSQPPLPEKRHLPGPG 1093

Query: 112  ISPGP 116
              PGP
Sbjct: 1094 QQPGP 1098


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 41/155 (26%), Positives = 61/155 (39%), Gaps = 14/155 (9%)

Query: 4    GGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRP---RSPEPAAPSGVRGSTWTRR 60
            GGP  + R   +PK P     + +   S +T P    P   + PE A  S    + +T  
Sbjct: 1159 GGPKCADRPSVAPKDPLQVPTNTE--TSEETRPSLDFPQEAKEPETAEESAPDSTEFTEA 1216

Query: 61   RDTPRRAGPTALSRYVGHLWMGRRPPSPEARG-PVPRSSAASRARRSLASPGISPGPLTA 119
              +P  A    +    G L   + PPS    G P P  S A+ A       G SP P   
Sbjct: 1217 LRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPH-----GSSPTP--- 1268

Query: 120  TIGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPM 154
             +G  + G G  Q     + +  P ++ G+  AP+
Sbjct: 1269 GVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPV 1303


>gi|224465238 hypothetical protein LOC283999 [Homo sapiens]
          Length = 394

 Score = 37.4 bits (85), Expect = 0.027
 Identities = 38/115 (33%), Positives = 43/115 (37%), Gaps = 23/115 (20%)

Query: 8   RSPRSGTSPKGPWSSTGHVQFG-----KSPQTWPRRTRPRSPE---PAAPSGVRGSTWTR 59
           R+   G SP G W  +   +F       SP    R  RP+      PA P G RG    R
Sbjct: 79  RAQGPGASPWGRWDWSPSPRFAARLSTSSPFPQGRAQRPQRGGVDLPATPGGPRGQCAGR 138

Query: 60  RRDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISP 114
             D  RRAG              R  P P  R P PR   A R  R  A+P  SP
Sbjct: 139 SGDVLRRAG------------RRRARPPPVPRLPAPR---APRRPRGPATPDPSP 178


>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 1006

 Score = 37.4 bits (85), Expect = 0.027
 Identities = 44/153 (28%), Positives = 53/153 (34%), Gaps = 35/153 (22%)

Query: 4   GGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDT 63
           G PP+ P   T+P   W         +SP T PR T P       P+   G +   +R  
Sbjct: 315 GTPPQQP---TAPSSEWPGPQ-----RSPGTGPRWTAPLPRPAPLPAKRPGDSPASKRPR 366

Query: 64  PRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTATIGG 123
           P    P A           R PP  E   P+  S AA              GP T   G 
Sbjct: 367 PGGVSPEA-----------RDPPKGE--NPLCSSEAAGET-----------GP-TQVRGP 401

Query: 124 AVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMEL 156
              GGG  QG+    K   PG+ V    AP  L
Sbjct: 402 DALGGGRLQGKGREGKA--PGEGVSPRPAPPRL 432


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 37.4 bits (85), Expect = 0.027
 Identities = 45/153 (29%), Positives = 55/153 (35%), Gaps = 34/153 (22%)

Query: 5   GPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPR-------SPEP------AAPSG 51
           G P SP  G  P  PW+ +        P T P   RP+        P P          G
Sbjct: 679 GSPSSPAPGPPPGAPWAFS---YLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEG 735

Query: 52  VRGSTWTRRRDTPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARR------ 105
             GST        RR G +AL R    +      P+P ARG     S A RARR      
Sbjct: 736 PVGSTLGSYATLTRRPGRSALVRTSPSV-----TPTP-ARGTPRSQSFALRARRKGPPPP 789

Query: 106 ------SLASPGISPGPLTATIGGAVAGGGPRQ 132
                 S++ P   P PL  + G      GPR+
Sbjct: 790 PPKRLSSVSGPSPEPPPLDESPGPKEGATGPRR 822


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,267,706
Number of Sequences: 37866
Number of extensions: 1228544
Number of successful extensions: 6780
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 391
Number of HSP's that attempted gapping in prelim test: 6212
Number of HSP's gapped (non-prelim): 877
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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