BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|38505213 YTH domain containing 2 [Homo sapiens] (1430 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|38505213 YTH domain containing 2 [Homo sapiens] 2860 0.0 gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 334 3e-91 gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 320 5e-87 gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 288 3e-77 gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 281 4e-75 gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 268 4e-71 gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 261 3e-69 gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 261 3e-69 gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi... 200 9e-51 gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 186 2e-46 gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi... 160 6e-39 gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 160 8e-39 gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] 159 1e-38 gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 159 2e-38 gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi... 157 9e-38 gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi... 150 1e-35 gi|166851804 tudor domain containing 9 [Homo sapiens] 149 1e-35 gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 136 2e-31 gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po... 132 2e-30 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 130 7e-30 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 127 6e-29 gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom... 108 5e-23 gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo... 86 3e-16 gi|31377750 YTH domain family, member 1 [Homo sapiens] 71 7e-12 gi|116235460 YTH domain family, member 3 [Homo sapiens] 67 9e-11 gi|116812575 high glucose-regulated protein 8 [Homo sapiens] 66 2e-10 gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 49 3e-05 gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 49 3e-05 gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 49 3e-05 gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapi... 49 5e-05 >gi|38505213 YTH domain containing 2 [Homo sapiens] Length = 1430 Score = 2860 bits (7415), Expect = 0.0 Identities = 1430/1430 (100%), Positives = 1430/1430 (100%) Query: 1 MSRPSSVSPRQPAPGGGGGGGPSPCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGD 60 MSRPSSVSPRQPAPGGGGGGGPSPCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGD Sbjct: 1 MSRPSSVSPRQPAPGGGGGGGPSPCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGD 60 Query: 61 QREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLT 120 QREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLT Sbjct: 61 QREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLT 120 Query: 121 HNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQIPVK 180 HNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQIPVK Sbjct: 121 HNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQIPVK 180 Query: 181 RGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIP 240 RGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIP Sbjct: 181 RGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIP 240 Query: 241 CRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTL 300 CRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTL Sbjct: 241 CRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTL 300 Query: 301 MAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYF 360 MAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYF Sbjct: 301 MAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYF 360 Query: 361 GSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEEKQQTTLTEWYSAQEN 420 GSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEEKQQTTLTEWYSAQEN Sbjct: 361 GSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEEKQQTTLTEWYSAQEN 420 Query: 421 SFKPESQRQRTVLNVTDEYDLLDDGGDAVFSQLTEKDVNCLEPWLIKEMDACLSDIWLHK 480 SFKPESQRQRTVLNVTDEYDLLDDGGDAVFSQLTEKDVNCLEPWLIKEMDACLSDIWLHK Sbjct: 421 SFKPESQRQRTVLNVTDEYDLLDDGGDAVFSQLTEKDVNCLEPWLIKEMDACLSDIWLHK 480 Query: 481 DIDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNG 540 DIDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNG Sbjct: 481 DIDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNG 540 Query: 541 WMALDWAKHFGQTEIVDLLESYSASLEFGNLDESSLVQTNGSDLSAEDRELLKAYHHSFD 600 WMALDWAKHFGQTEIVDLLESYSASLEFGNLDESSLVQTNGSDLSAEDRELLKAYHHSFD Sbjct: 541 WMALDWAKHFGQTEIVDLLESYSASLEFGNLDESSLVQTNGSDLSAEDRELLKAYHHSFD 600 Query: 601 DEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFM 660 DEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFM Sbjct: 601 DEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFM 660 Query: 661 LHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFV 720 LHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFV Sbjct: 661 LHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFV 720 Query: 721 TMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHT 780 TMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHT Sbjct: 721 TMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHT 780 Query: 781 KLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPH 840 KLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPH Sbjct: 781 KLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPH 840 Query: 841 LGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMAL 900 LGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMAL Sbjct: 841 LGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMAL 900 Query: 901 LRAFQAWQKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRD 960 LRAFQAWQKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRD Sbjct: 901 LRAFQAWQKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRD 960 Query: 961 VNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPPA 1020 VNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPPA Sbjct: 961 VNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPPA 1020 Query: 1021 NGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNALQEPSSF 1080 NGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNALQEPSSF Sbjct: 1021 NGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNALQEPSSF 1080 Query: 1081 RVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRA 1140 RVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRA Sbjct: 1081 RVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRA 1140 Query: 1141 PSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRK 1200 PSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRK Sbjct: 1141 PSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRK 1200 Query: 1201 SSADTEFSDECTTAERVLMKSPSPALHPPQKYKDRGILHPKRGTEDRSDQSSLKSTDSSS 1260 SSADTEFSDECTTAERVLMKSPSPALHPPQKYKDRGILHPKRGTEDRSDQSSLKSTDSSS Sbjct: 1201 SSADTEFSDECTTAERVLMKSPSPALHPPQKYKDRGILHPKRGTEDRSDQSSLKSTDSSS 1260 Query: 1261 YPSPCASPSPPSSGKGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKL 1320 YPSPCASPSPPSSGKGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKL Sbjct: 1261 YPSPCASPSPPSSGKGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKL 1320 Query: 1321 NRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLP 1380 NRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLP Sbjct: 1321 NRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLP 1380 Query: 1381 FQFAHHLLNPWNDNKKVQISRDGQELEPLVGEQLLQLWERLPLGEKNTTD 1430 FQFAHHLLNPWNDNKKVQISRDGQELEPLVGEQLLQLWERLPLGEKNTTD Sbjct: 1381 FQFAHHLLNPWNDNKKVQISRDGQELEPLVGEQLLQLWERLPLGEKNTTD 1430 >gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1 [Homo sapiens] Length = 1008 Score = 334 bits (857), Expect = 3e-91 Identities = 212/594 (35%), Positives = 329/594 (55%), Gaps = 64/594 (10%) Query: 589 RELLKAYHHS-------FDDEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDR 641 REL + Y S +D+KVDL+LI+ L+ I + GA+L+FLPG+D I L D Sbjct: 448 RELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDL 507 Query: 642 ILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVV 701 ++ + + ++ + LHS M T +Q +V K P GVRKI+++TNIAETSIT++DVV Sbjct: 508 LM---SQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVV 564 Query: 702 FVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNML 761 +VID GK+KE FD N ++ + W+SKA+A QRKGRAGR +PG C+ L++ LR + Sbjct: 565 YVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLD 624 Query: 762 EFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDT 821 ++Q PE+LR PL+ELCL K+L IA FL + +PP V +++ L ++A+D Sbjct: 625 DYQLPEILRTPLEELCLQIKILRLGG--IAYFLSRLMDPPSNEAVLLSIRHLMELNALDK 682 Query: 822 WEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRA 881 E+LT LG HLA LPVEPH+GKM+L + CLDP+LTIA +L+++DPFV+P +++ Sbjct: 683 QEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIP--LGKEKI 740 Query: 882 AMLCRKRFTAGAFSDHMALLRAFQAWQKARSDG--WERAFCEKNFLSQATMEIIIGMRTQ 939 A RK SDH+ ++ AF+ W++AR G +E+ +C + FLS T++++ M+ Q Sbjct: 741 ADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQ 800 Query: 940 LLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEK 999 L +GFV +R D + N NS+N ++KA + AG+YP + + R NL G K K Sbjct: 801 FAEHLLGAGFVSSRNPKD-PESNINSDNEKIIKAVICAGLYPKVAKI-RLNL---GKKRK 855 Query: 1000 KVRFHPAS---VLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVT 1056 V+ + + V P+ + + +WLIY R I + C+ V+ Sbjct: 856 MVKVYTKTDGLVAVHPKSVNVEQTD--------FHYNWLIYHLKMRTSSI-YLYDCTEVS 906 Query: 1057 PVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLE 1116 P +L F G + + QE + +DEW+ F Sbjct: 907 PYCLLFFGGDISIQKDNDQE---------------------------TIAVDEWIVFQSP 939 Query: 1117 PEAASLLLQLRQKWHSLFLRRMRAPSK-PWSQV---DEATIRAIIAVLSTEEQS 1166 A L+ +LR++ L ++ +P W+ D A + AII ++ T+E++ Sbjct: 940 ARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKA 993 Score = 194 bits (493), Expect = 5e-49 Identities = 144/428 (33%), Positives = 219/428 (51%), Gaps = 47/428 (10%) Query: 15 GGGGGGGPSPCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTE 74 G GGGGG G GG GR G R +I + A ++ + + E + E Sbjct: 35 GSGGGGGGGGGGRGGRGRHPGHLKGR-----EIGMWYAKKQGQKNKEAERQ--------E 81 Query: 75 RAFIH-------RLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAV 127 RA +H ++ Q L V K + ++ + H T T NT + Sbjct: 82 RAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPED----HGYGTEVSTKNTPCSE 137 Query: 128 RSL-IQRFPVTNKERTELLPKT----ERGNVFAVEAENREMSKTSGRLNNGIPQIPVKRG 182 L IQ + N+E+ + +R + + ++ EN +L + + Sbjct: 138 NKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQ-ENEPDGTLDQKLLEDLQKKKNDLR 196 Query: 183 ESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNG--IP 240 E FR+ LP + Q+E+V +I ++V +I GETG GKTTQ+ QF+LD+ + G Sbjct: 197 YIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSA 256 Query: 241 CRIFCTQPRRLAAIAVAERVAAERRERIGQ--TIGYQIRLESRVSPKT-LLTFCTNGVLL 297 CRI CTQPRR++AI+VAERVAAER E G + GYQIRL+SR+ K + +CT G++L Sbjct: 257 CRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIIL 316 Query: 298 RTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFI 357 + L + D LS+V+H+++DE+HER+ SD L+T ++DLL LK+IL SA L+ F Sbjct: 317 QWLQS-DPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFS 375 Query: 358 RYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKE-----------MLKYKKEKQQEEK 406 YFG+CP+I+I G F V E LED++ Y ++ M + +++EEK Sbjct: 376 EYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEK 435 Query: 407 QQTTLTEW 414 + W Sbjct: 436 EAIYKERW 443 >gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2 [Homo sapiens] Length = 994 Score = 320 bits (821), Expect = 5e-87 Identities = 208/594 (35%), Positives = 321/594 (54%), Gaps = 78/594 (13%) Query: 589 RELLKAYHHS-------FDDEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDR 641 REL + Y S +D+KVDL+LI+ L+ I + GA+L+FLPG+D I L D Sbjct: 448 RELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHD- 506 Query: 642 ILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVV 701 + M ++ +Q +V K P GVRKI+++TNIAETSIT++DVV Sbjct: 507 ----------------LLMSQVMFKSVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVV 550 Query: 702 FVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNML 761 +VID GK+KE FD N ++ + W+SKA+A QRKGRAGR +PG C+ L++ LR + Sbjct: 551 YVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLD 610 Query: 762 EFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDT 821 ++Q PE+LR PL+ELCL K+L IA FL + +PP V +++ L ++A+D Sbjct: 611 DYQLPEILRTPLEELCLQIKILRLGG--IAYFLSRLMDPPSNEAVLLSIRHLMELNALDK 668 Query: 822 WEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRA 881 E+LT LG HLA LPVEPH+GKM+L + CLDP+LTIA +L+++DPFV+P +++ Sbjct: 669 QEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIP--LGKEKI 726 Query: 882 AMLCRKRFTAGAFSDHMALLRAFQAWQKARSDG--WERAFCEKNFLSQATMEIIIGMRTQ 939 A RK SDH+ ++ AF+ W++AR G +E+ +C + FLS T++++ M+ Q Sbjct: 727 ADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQ 786 Query: 940 LLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEK 999 L +GFV +R D + N NS+N ++KA + AG+YP + + R NL G K K Sbjct: 787 FAEHLLGAGFVSSRNPKD-PESNINSDNEKIIKAVICAGLYPKVAKI-RLNL---GKKRK 841 Query: 1000 KVRFHPAS---VLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVT 1056 V+ + + V P+ + + +WLIY R I + C+ V+ Sbjct: 842 MVKVYTKTDGLVAVHPKSVNVEQTD--------FHYNWLIYHLKMRTSSI-YLYDCTEVS 892 Query: 1057 PVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLE 1116 P +L F G + + QE + +DEW+ F Sbjct: 893 PYCLLFFGGDISIQKDNDQE---------------------------TIAVDEWIVFQSP 925 Query: 1117 PEAASLLLQLRQKWHSLFLRRMRAPSK-PWSQV---DEATIRAIIAVLSTEEQS 1166 A L+ +LR++ L ++ +P W+ D A + AII ++ T+E++ Sbjct: 926 ARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKA 979 Score = 194 bits (493), Expect = 5e-49 Identities = 144/428 (33%), Positives = 219/428 (51%), Gaps = 47/428 (10%) Query: 15 GGGGGGGPSPCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTE 74 G GGGGG G GG GR G R +I + A ++ + + E + E Sbjct: 35 GSGGGGGGGGGGRGGRGRHPGHLKGR-----EIGMWYAKKQGQKNKEAERQ--------E 81 Query: 75 RAFIH-------RLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAV 127 RA +H ++ Q L V K + ++ + H T T NT + Sbjct: 82 RAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPED----HGYGTEVSTKNTPCSE 137 Query: 128 RSL-IQRFPVTNKERTELLPKT----ERGNVFAVEAENREMSKTSGRLNNGIPQIPVKRG 182 L IQ + N+E+ + +R + + ++ EN +L + + Sbjct: 138 NKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQ-ENEPDGTLDQKLLEDLQKKKNDLR 196 Query: 183 ESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNG--IP 240 E FR+ LP + Q+E+V +I ++V +I GETG GKTTQ+ QF+LD+ + G Sbjct: 197 YIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSA 256 Query: 241 CRIFCTQPRRLAAIAVAERVAAERRERIGQ--TIGYQIRLESRVSPKT-LLTFCTNGVLL 297 CRI CTQPRR++AI+VAERVAAER E G + GYQIRL+SR+ K + +CT G++L Sbjct: 257 CRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIIL 316 Query: 298 RTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFI 357 + L + D LS+V+H+++DE+HER+ SD L+T ++DLL LK+IL SA L+ F Sbjct: 317 QWLQS-DPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFS 375 Query: 358 RYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKE-----------MLKYKKEKQQEEK 406 YFG+CP+I+I G F V E LED++ Y ++ M + +++EEK Sbjct: 376 EYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEK 435 Query: 407 QQTTLTEW 414 + W Sbjct: 436 EAIYKERW 443 >gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens] Length = 1369 Score = 288 bits (736), Expect = 3e-77 Identities = 197/581 (33%), Positives = 306/581 (52%), Gaps = 77/581 (13%) Query: 603 KVDLDLIMHLLYNICHSCD----AGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQV 658 K++LDLI+ LL + S GAVLIFLPG I L D +L +D+RF + RY+V Sbjct: 844 KINLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYD-LLSNDRRFY--SERYKV 900 Query: 659 FMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALN 718 LHS + T DQ PP GVRKI+L+TNIAET IT+ DVVFVID+G+ KE + + Sbjct: 901 IALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESS 960 Query: 719 FVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCL 778 ++ L ++SKASA+QR+GRAGR R G CFR+++R RF+ +++ PE+LR+PL+ELCL Sbjct: 961 QMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCL 1020 Query: 779 HTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWE-DLTELGYHLADLPV 837 H + + P DFL KA +PP ++ NA+ +L+ I A + E LT LG HLA LPV Sbjct: 1021 HI-MKCNLGSP-EDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPV 1078 Query: 838 EPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDH 897 +GKM++ + CLDP+ T+A + + PF P +K A L K A A SDH Sbjct: 1079 NVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTP--IGRKDEADLA-KSALAMADSDH 1135 Query: 898 MALLRAFQAWQKARSDGWERA---FCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARG 954 + + A+ W+KAR +G R+ +C +NFL++ ++ + ++ +L+ ++A+GF + Sbjct: 1136 LTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTT 1195 Query: 955 G----GDIRDVNTNSENWAVVKAALVAGMYPNL--------VHVDRENLVLTGPKEKKVR 1002 G+ + + A++KA LVAG+Y N+ V V + + + K + Sbjct: 1196 STSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQ 1255 Query: 1003 FHPASVLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILV 1062 HP+SV Q WL+Y E R R+ +R + +TP +L+ Sbjct: 1256 VHPSSVNRDLQ-----------------THGWLLYQEKIRYARV-YLRETTLITPFPVLL 1297 Query: 1063 FCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASL 1122 F G D E++ + L +D W++F + A + Sbjct: 1298 FGG-------------------------DIEVQHRE----RLLSIDGWIYFQAPVKIAVI 1328 Query: 1123 LLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTE 1163 QLR S+ +++ P S ++ ++ I ++ TE Sbjct: 1329 FKQLRVLIDSVLRKKLENPK--MSLENDKILQIITELIKTE 1367 Score = 193 bits (490), Expect = 1e-48 Identities = 107/228 (46%), Positives = 145/228 (63%), Gaps = 9/228 (3%) Query: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKN---GIPCRIFCT 246 RQ LPVF+ ++ IV+ +K ++VV++ GETGSGK+TQ+P FLL+D N C I CT Sbjct: 569 RQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCT 628 Query: 247 QPRRLAAIAVAERVAAERRERIG-----QTIGYQIRLESRVSPKTLLTFCTNGVLLRTLM 301 QPRR++A+++A RV E G GYQIR+ESR T L +CT GVLLR L Sbjct: 629 QPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQ 688 Query: 302 AGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFG 361 D LS V+HVIVDEVHER SDFLL L+++LQK L LIL SA +D F YF Sbjct: 689 E-DGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTYFT 747 Query: 362 SCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEEKQQT 409 CP++ I GR + V+ LEDI+ TG+ ++ +Y ++ +EE++ T Sbjct: 748 HCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVT 795 >gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo sapiens] Length = 1386 Score = 281 bits (718), Expect = 4e-75 Identities = 186/502 (37%), Positives = 284/502 (56%), Gaps = 49/502 (9%) Query: 600 DDEKVDLDLIMHLLYNIC---HSCDAGAVLIFLPGYDEIVGLRDRI----LFDDKRFADN 652 D EKV+L+LI LL I HS GA+L+FLPG EI L +++ LF+++R Sbjct: 822 DFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRR---- 877 Query: 653 THRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEK 712 ++R + LHS++ + +Q+ V PPAGV KII+STNIAETSIT++DVV+VIDSGK+KEK Sbjct: 878 SNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEK 937 Query: 713 SFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQN-MLEFQTPELLRM 771 +DA + L+ ++S+A+A+QRKGRAGR G+CF LF+ + + +L+ Q PE+ R+ Sbjct: 938 RYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRV 997 Query: 772 PLQELCLHTKLLAPVNC-PIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGY 830 PL++LCL K+L + + + EPP +R + L+ + A+ E LT LGY Sbjct: 998 PLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGY 1057 Query: 831 HLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLP----TQASQKRAAMLCR 886 HLA LPV+ +GK++L + +CLDP LTIA +LA++ PFV P +A+QK+ Sbjct: 1058 HLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEF--- 1114 Query: 887 KRFTAGAFSDHMALLRAFQAWQKARSDGWERA--FCEKNFLSQATMEIIIGMRTQLLGQL 944 A A SD++ALL+A++ WQ + +G + +C +NFLS ++ + ++ Q L Sbjct: 1115 ----AFANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELL 1170 Query: 945 RASGFV-----------RARGGGDIRD-----VNTNSENWAVVKAALVAGMYPNLVHVDR 988 GF RA+GG + D N+N+EN ++ A L A +YPN+V V Sbjct: 1171 SDIGFAREGLRAREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKS 1230 Query: 989 ENLVLTGPKEKKVRFHPAS-----VLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRA 1043 VR P S V Y I P++ ++ + +L+Y E + Sbjct: 1231 PEGKFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVN-YQVRHFDSPYLLYHEKIKT 1289 Query: 1044 HRIANIRCCSAVTPVTILVFCG 1065 R+ IR CS V+ +++F G Sbjct: 1290 SRVF-IRDCSMVSVYPLVLFGG 1310 Score = 225 bits (573), Expect = 3e-58 Identities = 133/295 (45%), Positives = 182/295 (61%), Gaps = 22/295 (7%) Query: 155 AVEAENREMSKTSGRLNNGIPQIPVKRGESEFDSF---RQSLPVFEKQEEIVKIIKENKV 211 +V AEN ++ K Q +K+ +F S RQSLP +E++E I+ ++++++V Sbjct: 513 SVHAENGKICK----------QFRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQV 562 Query: 212 VLIVGETGSGKTTQIPQFLLDDCFKNGIP---CRIFCTQPRRLAAIAVAERVAAERRERI 268 V+I G TG GKTTQIPQF+LDD NG P I CTQPRR++AI+VAERVA ER ER+ Sbjct: 563 VVISGMTGCGKTTQIPQFILDDSL-NGPPEKVANIICTQPRRISAISVAERVAKERAERV 621 Query: 269 GQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFL 328 G T+GYQIRLES S T L +CT GVLLR L GD+ L V+H+IVDEVHER SDFL Sbjct: 622 GLTVGYQIRLESVKSSATRLLYCTTGVLLRRL-EGDTALQGVSHIIVDEVHERTEESDFL 680 Query: 329 LTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTG 388 L L+D++ + P L++IL SA L+ LF YF SCPVI I GR F V + FLED + T Sbjct: 681 LLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTR 740 Query: 389 YTNKEMLKYKKEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLD 443 Y ++ Y + +Q K++ +F+ + R L++ D+ + D Sbjct: 741 YVLQDGSPYMRSMKQISKEKLKARR----NRTAFEEVEEDLRLSLHLQDQDSVKD 791 >gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens] Length = 1270 Score = 268 bits (684), Expect = 4e-71 Identities = 208/611 (34%), Positives = 296/611 (48%), Gaps = 66/611 (10%) Query: 600 DDEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVF 659 ++++ +LI LL I GAVL+FLPG++ I ++ + + +HRYQ+ Sbjct: 628 NEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHF---GSHRYQIL 684 Query: 660 MLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNF 719 LHS + +Q+KV P GV K+ILSTNIAETSIT+NDVV+VIDS K K K F A N Sbjct: 685 PLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNN 744 Query: 720 VTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLH 779 +T VW SK + QRKGRAGR RPG CF L SR RF+ + TPE+ R PL E+ L Sbjct: 745 MTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEIALS 804 Query: 780 TKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEP 839 KLL I FL KA EPPP V A L+ +DA+D ++LT LG LA LP+EP Sbjct: 805 IKLLRLGG--IGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEP 862 Query: 840 HLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMA 899 GKM++ + D I TIA + +PF+ ++ + + F FSDH+A Sbjct: 863 RFGKMMIMGCIFYVGDAICTIAAATCFPEPFI-----NEGKRLGYIHRNFAGNRFSDHVA 917 Query: 900 LLRAFQAWQKARSDGWER--AFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGD 957 LL FQAW AR G E FCE L+ AT+ + + QL L SGF Sbjct: 918 LLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINSGFPE---DCL 974 Query: 958 IRDVNTNS---ENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQY 1014 + V TN+ N VV + L G+YPN+ + + +LT + + H +SV Sbjct: 975 LTQVFTNTGPDNNLDVVISLLAFGVYPNVCYHKEKRKILT-TEGRNALIHKSSVNC---- 1029 Query: 1015 KKIPPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNAL 1074 P + Q P+ + ++ E R R + + + VTP+ +L+F AS + Sbjct: 1030 ----PFSSQD---MKYPSPFFVFGEKIRT-RAISAKGMTLVTPLQLLLF------ASKKV 1075 Query: 1075 QEPSSFRVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLF 1134 Q SD ++ + +D+W+ + EAA+ + LR +L Sbjct: 1076 Q--------------SDGQI----------VLVDDWIKLQISHEAAACITGLRAAMEALV 1111 Query: 1135 LRRMRAPSKPWSQVDEATIRAIIAVLSTEEQS-AGLQQPSG---IGQRPRPMSSEELPLA 1190 + + P+ SQ+D R + + S AG+ G G PRP Sbjct: 1112 VEVTKQPA-IISQLDPVNERMLNMIRQISRPSAAGINLMIGSTRYGDGPRPPKMARYDNG 1170 Query: 1191 SSWRSNNSRKS 1201 S +R S S Sbjct: 1171 SGYRRGGSSYS 1181 Score = 197 bits (501), Expect = 6e-50 Identities = 103/218 (47%), Positives = 147/218 (67%), Gaps = 6/218 (2%) Query: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKN--GIPCRIFCTQ 247 R+ LPV + + EI++ I +N VV+I G TG GKTTQ+PQF+LDD +N C I TQ Sbjct: 385 RELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNIVVTQ 444 Query: 248 PRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVS-PKTLLTFCTNGVLLRTLMAGDST 306 PRR++A++VAERVA ER E G++ GY +R ES + P + FCT GVLLR L AG Sbjct: 445 PRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAG--- 501 Query: 307 LSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVI 366 + ++HVIVDE+HERD +DFLL LRD++Q +P ++++L SA +D ++F YF +CP+I Sbjct: 502 IRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNCPII 561 Query: 367 YIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQE 404 + GR + V+E FLED ++ T + K KK+K + Sbjct: 562 EVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDD 599 >gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 [Homo sapiens] Length = 1155 Score = 261 bits (668), Expect = 3e-69 Identities = 169/507 (33%), Positives = 267/507 (52%), Gaps = 35/507 (6%) Query: 596 HHSFDDE-KVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTH 654 HH +DE +DLDL+ L+ +I + G +L FLPG+ EI G++ R+ + + Sbjct: 602 HHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRL---QEALGMHES 658 Query: 655 RYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSF 714 +Y + +HSN+ DQK + + PP GVRKI+L+TNIAETSIT+ND+V V+DSG KE+ + Sbjct: 659 KYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERY 718 Query: 715 DALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQ 774 D V+ L+ VW+S+A+ IQR+GRAGRC+ G + LF R R + M+ FQ PE+LR PL+ Sbjct: 719 DLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLE 778 Query: 775 ELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLAD 834 L L K+ P + +FL KA + P V AV +L+ I +D E LT LG LA Sbjct: 779 NLVLQAKIHMPEKTAV-EFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAH 837 Query: 835 LPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAM-LCRKRFTAGA 893 + +P L K ++ A + +CL P+L + L RDPF + + Q RA + + + + Sbjct: 838 ISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPF---SSSLQNRAEVDKVKALLSHDS 893 Query: 894 FSDHMALLRAFQAWQKA---RSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFV 950 SDH+A +RA W++ + + E+N L ++ I G+ Q + + V Sbjct: 894 GSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLV 953 Query: 951 RARGGGDIRDVNTN--SENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASV 1008 + N SE +VK L+AG+YPNL+ V + G ++ +F P SV Sbjct: 954 GKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQ------GKVTRQGKFKPNSV 1007 Query: 1009 LSQPQYKKI----PPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFC 1064 + + I N +A ++ + WL Y +++ +R S V P+ +L+ Sbjct: 1008 TYRTKSGNILLHKSTINREATRLR---SRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLT 1064 Query: 1065 -------GPARLASNALQEPSSFRVDG 1084 R A+ +L + R++G Sbjct: 1065 DGDVHIRDDGRRATISLSDSDLLRLEG 1091 Score = 168 bits (425), Expect = 4e-41 Identities = 117/345 (33%), Positives = 190/345 (55%), Gaps = 32/345 (9%) Query: 83 QSLGLVSKSKGKGANR-YLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKER 141 +SLGLV ++ + Y ++ ET T + + + + +PV E Sbjct: 274 KSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPV---ES 330 Query: 142 TELLPKTERGNVFAVEAENREMSKTSGRLNN---GIPQIP------VKRGESEFDSFRQS 192 + + P+ + + + K SG L++ G P +P V+ +S + +R+ Sbjct: 331 SWIAPELRLQS-----DDILPLGKDSGPLSDPITGKPYVPLLEAEEVRLSQSLLELWRRR 385 Query: 193 LPVFEK---------QEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNG--IPC 241 PV+++ ++ I+ I+++ VV+I G+TG GKTT+IPQ LL+ G C Sbjct: 386 GPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARC 445 Query: 242 RIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKT-LLTFCTNGVLLRTL 300 + TQPRR++A++VA+RV+ E + + +G+Q+RLES+ + L FCT G+LLR L Sbjct: 446 NVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKL 505 Query: 301 MAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYF 360 + S L V+HVIVDEVHERD +DFLL L+ L + +P L+L+L SA D F RYF Sbjct: 506 QSNPS-LEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYF 564 Query: 361 GSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEE 405 G CPVI + G + VKE +LEDIL G ++ + +++ + ++E Sbjct: 565 GGCPVIKVPGFMYPVKEHYLEDILAKLG-KHQYLHRHRHHESEDE 608 >gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 [Homo sapiens] Length = 1194 Score = 261 bits (668), Expect = 3e-69 Identities = 169/507 (33%), Positives = 267/507 (52%), Gaps = 35/507 (6%) Query: 596 HHSFDDE-KVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTH 654 HH +DE +DLDL+ L+ +I + G +L FLPG+ EI G++ R+ + + Sbjct: 641 HHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRL---QEALGMHES 697 Query: 655 RYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSF 714 +Y + +HSN+ DQK + + PP GVRKI+L+TNIAETSIT+ND+V V+DSG KE+ + Sbjct: 698 KYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERY 757 Query: 715 DALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQ 774 D V+ L+ VW+S+A+ IQR+GRAGRC+ G + LF R R + M+ FQ PE+LR PL+ Sbjct: 758 DLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLE 817 Query: 775 ELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLAD 834 L L K+ P + +FL KA + P V AV +L+ I +D E LT LG LA Sbjct: 818 NLVLQAKIHMPEKTAV-EFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAH 876 Query: 835 LPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAM-LCRKRFTAGA 893 + +P L K ++ A + +CL P+L + L RDPF + + Q RA + + + + Sbjct: 877 ISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPF---SSSLQNRAEVDKVKALLSHDS 932 Query: 894 FSDHMALLRAFQAWQKA---RSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFV 950 SDH+A +RA W++ + + E+N L ++ I G+ Q + + V Sbjct: 933 GSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLV 992 Query: 951 RARGGGDIRDVNTN--SENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASV 1008 + N SE +VK L+AG+YPNL+ V + G ++ +F P SV Sbjct: 993 GKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQ------GKVTRQGKFKPNSV 1046 Query: 1009 LSQPQYKKI----PPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFC 1064 + + I N +A ++ + WL Y +++ +R S V P+ +L+ Sbjct: 1047 TYRTKSGNILLHKSTINREATRLR---SRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLT 1103 Query: 1065 -------GPARLASNALQEPSSFRVDG 1084 R A+ +L + R++G Sbjct: 1104 DGDVHIRDDGRRATISLSDSDLLRLEG 1130 Score = 168 bits (425), Expect = 4e-41 Identities = 117/345 (33%), Positives = 190/345 (55%), Gaps = 32/345 (9%) Query: 83 QSLGLVSKSKGKGANR-YLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKER 141 +SLGLV ++ + Y ++ ET T + + + + +PV E Sbjct: 313 KSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPV---ES 369 Query: 142 TELLPKTERGNVFAVEAENREMSKTSGRLNN---GIPQIP------VKRGESEFDSFRQS 192 + + P+ + + + K SG L++ G P +P V+ +S + +R+ Sbjct: 370 SWIAPELRLQS-----DDILPLGKDSGPLSDPITGKPYVPLLEAEEVRLSQSLLELWRRR 424 Query: 193 LPVFEK---------QEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNG--IPC 241 PV+++ ++ I+ I+++ VV+I G+TG GKTT+IPQ LL+ G C Sbjct: 425 GPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARC 484 Query: 242 RIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKT-LLTFCTNGVLLRTL 300 + TQPRR++A++VA+RV+ E + + +G+Q+RLES+ + L FCT G+LLR L Sbjct: 485 NVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKL 544 Query: 301 MAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYF 360 + S L V+HVIVDEVHERD +DFLL L+ L + +P L+L+L SA D F RYF Sbjct: 545 QSNPS-LEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYF 603 Query: 361 GSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEE 405 G CPVI + G + VKE +LEDIL G ++ + +++ + ++E Sbjct: 604 GGCPVIKVPGFMYPVKEHYLEDILAKLG-KHQYLHRHRHHESEDE 647 >gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapiens] Length = 1143 Score = 200 bits (508), Expect = 9e-51 Identities = 127/364 (34%), Positives = 192/364 (52%), Gaps = 16/364 (4%) Query: 602 EKVDLDLIMHLLYNICHSC---DAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQV 658 EK+D + +L +I H + G +L+FL G EI +L + +A +T R+ V Sbjct: 355 EKLDPRPFLRVLESIDHKYPPEERGDLLVFLSGMAEI----SAVLEAAQTYASHTQRWVV 410 Query: 659 FMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALN 718 LHS + +DQ KV P GVRK ILSTNIAETS+T++ + FV+DSGKVKE S+D Sbjct: 411 LPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQA 470 Query: 719 FVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCL 778 + L+ WIS+ASA QRKGRAGR PG+CFRL++ + + PE+ R+ L L L Sbjct: 471 KLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLVL 530 Query: 779 HTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVE 838 K ++ + F+ EPPP + A+ L+ A+D+ E LT +G LA LPV+ Sbjct: 531 QMKSMSVGDPRTFPFI----EPPPPASLETAILYLRDQGALDSSEALTPIGSLLAQLPVD 586 Query: 839 PHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHM 898 +GKM++ + ++P+LTIA L+ + PF Q+S + AA +R D Sbjct: 587 VVIGKMLILGSMFSLVEPVLTIAAALSVQSPFTRSAQSSPECAA---ARRPLESDQGDPF 643 Query: 899 ALLRAFQAWQKARSDGW--ERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGG 956 L F AW + +S+ R +C + + + + + +R Q L G + Sbjct: 644 TLFNVFNAWVQVKSERSRNSRKWCRRRGIEEHRLYEMANLRRQFKELLEDHGLLAGAQAA 703 Query: 957 DIRD 960 + D Sbjct: 704 QVGD 707 Score = 149 bits (375), Expect = 2e-35 Identities = 80/190 (42%), Positives = 121/190 (63%), Gaps = 6/190 (3%) Query: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPR 249 R +LP+ + I++ +KE++VV++ G+TG GK+TQ+PQ+LL F + + CTQPR Sbjct: 159 RAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSH-----VACTQPR 213 Query: 250 RLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLST 309 R+A I++A+RV E + G +GYQIR ES S T + F T G+LLR + + +L Sbjct: 214 RIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQR-EPSLPQ 272 Query: 310 VTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQ 369 +IVDEVHER +DFLL L+ LL P LK+IL SA ++++LF YF + PV+ + Sbjct: 273 YEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSYFSNAPVVQVP 332 Query: 370 GRPFEVKEMF 379 GR F + ++ Sbjct: 333 GRLFPITVVY 342 >gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapiens] Length = 795 Score = 186 bits (471), Expect = 2e-46 Identities = 141/450 (31%), Positives = 221/450 (49%), Gaps = 47/450 (10%) Query: 618 HSCDA--GAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLK 675 H C+ G +L+FL G +EI RI + ++ L+S + Q+++ + Sbjct: 343 HMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFE 402 Query: 676 NPP------AGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWIS 729 PP A RK+++STNIAETS+T++ VVFVID G K+K ++ V L + IS Sbjct: 403 PPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAIS 462 Query: 730 KASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQT-PELLRMPLQELCLHTKLLAPVNC 788 KASA QR GRAGR RPG CFRL++ ++ ++ T PE+LR L + L K L + Sbjct: 463 KASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDL 522 Query: 789 PIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCA 848 DF+ +PP + A+++L + A++ DLTELG +A+ P++P L KMV+ + Sbjct: 523 VHFDFM----DPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIAS 578 Query: 849 VVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAW- 907 C + +L+I L+ FV PT+A K+AA + RF A DH+ LL + A+ Sbjct: 579 CDYNCSNEVLSITAMLSVPQCFVRPTEA--KKAADEAKMRF-AHIDGDHLTLLNVYHAFK 635 Query: 908 QKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSEN 967 Q S W C NF++ ++ +R QL + R RD N Sbjct: 636 QNHESVQW----CYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYIN--- 688 Query: 968 WAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPPANGQAAAI 1027 ++ ALV G + + H++R LT + V+ HP++VL Sbjct: 689 ---IRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVLDH---------------- 729 Query: 1028 KALPTDWLIYDEMTRAHRIANIRCCSAVTP 1057 +W++Y+E + IR C+ + P Sbjct: 730 ---KPEWVLYNEFVLTTK-NYIRTCTDIKP 755 Score = 142 bits (357), Expect = 3e-33 Identities = 85/206 (41%), Positives = 126/206 (61%), Gaps = 10/206 (4%) Query: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCR-IFCTQP 248 R LPV+E ++ I+ ++ ++VGETGSGKTTQIPQ+ ++ P R + CTQP Sbjct: 134 RLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQP 193 Query: 249 RRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLS 308 RR+AA++VA+RVA E +GQ +GY IR E S KT+L + T+G+LLR M D L Sbjct: 194 RRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAM-NDPLLE 252 Query: 309 TVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYI 368 +I+DE HER +D L+ L++++++ LK+I+ SA LD F YF +CP++ I Sbjct: 253 RYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTI 312 Query: 369 QGR--PFEV------KEMFLEDILRT 386 GR P E+ + +LE +RT Sbjct: 313 PGRTHPVEIFYTPEPERDYLEAAIRT 338 >gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapiens] Length = 707 Score = 160 bits (406), Expect = 6e-39 Identities = 109/385 (28%), Positives = 180/385 (46%), Gaps = 17/385 (4%) Query: 625 VLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKI 684 +L+FL G +EI + K D V L++++ + Q +V + P G RK+ Sbjct: 291 ILVFLTGQEEIEAMSKTCRDIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKV 350 Query: 685 ILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCR 744 I+STNIAETSIT+ + +V+D+G VK K ++ + + +L + +SK A QR GRAGR Sbjct: 351 IISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGRED 410 Query: 745 PGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPAL 804 GIC+RL++ F+ + PE+ R L + L + N DF+ K P P Sbjct: 411 SGICYRLYTEDEFEKFDKMTVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSK-PSPDHIQ 469 Query: 805 IVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTL 864 + +L ++ D LT +G +A P+EP K +L + C + ILTI L Sbjct: 470 AAIAQLDLLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSLL 529 Query: 865 AYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCEKNF 924 + VL S++ RK+F + DHM LL ++ ++ G + +C++NF Sbjct: 530 SVDS--VLHNPPSRREEVQGVRKKFISSE-GDHMTLLNIYRTFKNL---GGNKDWCKENF 583 Query: 925 LSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLV 984 ++ M ++ +R QL A GD+ V+ L ++ + Sbjct: 584 VNSKNMTLVAEVRAQLRDICLKMSMPIASSRGDVES----------VRRCLAHSLFMSTA 633 Query: 985 HVDRENLVLTGPKEKKVRFHPASVL 1009 + + T + V HP+SVL Sbjct: 634 ELQPDGTYATTDTHQPVAIHPSSVL 658 Score = 136 bits (342), Expect = 2e-31 Identities = 80/197 (40%), Positives = 124/197 (62%), Gaps = 12/197 (6%) Query: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCF-KNGIPCRIFCTQP 248 R+SLP+F+ + +++ ++ +++GETGSGKTTQIPQ+L + + GI I TQP Sbjct: 71 RRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQGI---IAVTQP 127 Query: 249 RRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLS 308 RR+AAI++A RV+ E+R +G+ +GY +R + S T + F T+G+LLR ++ DS L Sbjct: 128 RRVAAISLATRVSDEKRTELGKLVGYTVRFDDVTSEDTRIKFLTDGMLLREAIS-DSLLR 186 Query: 309 TVTHVIVDEVHERDRFSDFLL------TKLRDLLQKHPTLKLILSSAALDVNLFIRYFGS 362 + VI+DE HER +D L K R L K P LK+I+ SA +DV+LF +YF Sbjct: 187 KYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLP-LKVIVMSATMDVDLFSQYFNG 245 Query: 363 CPVIYIQGRPFEVKEMF 379 PV+Y++GR ++ + Sbjct: 246 APVLYLEGRQHPIQVFY 262 >gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] Length = 1220 Score = 160 bits (405), Expect = 8e-39 Identities = 112/395 (28%), Positives = 199/395 (50%), Gaps = 23/395 (5%) Query: 623 GAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVR 682 G +L+FL G +EI + + K + + ++S + + Q ++ P G R Sbjct: 774 GDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSR 833 Query: 683 KIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGR 742 K++++TNIAETS+T++ + +V+D G VK+K +++ + L + IS+A A QR GRAGR Sbjct: 834 KVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGR 893 Query: 743 CRPGICFRLFSRLRFQN-MLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPP 801 PG C+RL++ +++ ML PE+ R L L K + + DF+ + P Sbjct: 894 TGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFM----DAP 949 Query: 802 PALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIA 861 P + A++ L T+ A+D LT LG +A+ P+EP L KM++ +V L C + +LTI Sbjct: 950 PMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIV 1009 Query: 862 CTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCE 921 L+ ++ F P K+A +K DH+ LL + +W +++ + +C Sbjct: 1010 SMLSVQNVFYRP---KDKQALADQKKAKFHQTEGDHLTLLAVYNSW---KNNKFSNPWCY 1063 Query: 922 KNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYP 981 +NF+ ++ +R Q+LG + DV + ++ V+ A+ +G + Sbjct: 1064 ENFIQARSLRRAQDIRKQMLGIMDRHKL----------DVVSCGKSTVRVQKAICSGFFR 1113 Query: 982 NLVHVDRENLVLTGPKEKKVRFHPASVL--SQPQY 1014 N D + T ++ V HP+S L QP++ Sbjct: 1114 NAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEW 1148 Score = 151 bits (381), Expect = 5e-36 Identities = 101/300 (33%), Positives = 166/300 (55%), Gaps = 32/300 (10%) Query: 102 VKKKDGSETAHAMMTCNLT---HNTKHAVRSL-IQRFPV-TNKERTELLPKTERGNVFAV 156 VK DGS + AMM L K A R + P+ NK + LP Sbjct: 465 VKNPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWVDPLP---------- 514 Query: 157 EAENREMSKTS---GRLNNGIPQIPV-----------KRGESEFDSFRQSLPVFEKQEEI 202 +AE R+++ G + N IP+ K+ + R+SLP+++ +E++ Sbjct: 515 DAEGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQMSILEQRESLPIYKLKEQL 574 Query: 203 VKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAA 262 V+ + +N++++++GETGSGKTTQI Q+L + + + +I CTQPRR+AA++VA+RV+ Sbjct: 575 VQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSR--GKIGCTQPRRVAAMSVAKRVSE 632 Query: 263 ERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERD 322 E +GQ +GY IR E SP+T++ + T+G+LLR + D L+ +++DE HER Sbjct: 633 EFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLI-DPDLTQYAIIMLDEAHERT 691 Query: 323 RFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLED 382 +D L L+ +QK +KLI++SA LD F +YF P+ I GR + V+ ++ ++ Sbjct: 692 IHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKE 751 >gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] Length = 1041 Score = 159 bits (403), Expect = 1e-38 Identities = 116/392 (29%), Positives = 193/392 (49%), Gaps = 21/392 (5%) Query: 623 GAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVR 682 G +L+FL G +EI + + +R V +++N+ + Q ++ + P G R Sbjct: 609 GDILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGAR 668 Query: 683 KIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGR 742 K++++TNIAETS T+ +++V+D G K+KS++ + L + SKASA QR GRAGR Sbjct: 669 KVVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGR 728 Query: 743 CRPGICFRLFSRLRFQNMLEFQT-PELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPP 801 G CFRL++ +Q+ LE T PE+ R L + L K L + DFL +PP Sbjct: 729 VAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFL----DPP 784 Query: 802 PALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIA 861 P + ++ L + A++ +LT G +A+LPV+P L KM+L + C + ILT+A Sbjct: 785 PYETLLLTLEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVA 844 Query: 862 CTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCE 921 L+ + + A F G DH+ LL + W ++ G+ +C Sbjct: 845 AMLSVNNSIFYRPKDKVVHADNARVNFFLPG--GDHLVLLNVYTQWAES---GYSSQWCC 899 Query: 922 KNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYP 981 +NF+ +M +R QL G L R G +++ ++ V+ A+ AG + Sbjct: 900 ENFVQFRSMRRARDVREQLEGLLE-----RVEVG-----LSSCQGDYIRVRKAITAGYFY 949 Query: 982 NLVHVDRENLVLTGPKEKKVRFHPASVLSQPQ 1013 + + R T +++ V HP S L + Q Sbjct: 950 HTARLTRSG-YRTVKQQQTVFIHPNSSLFEQQ 980 Score = 152 bits (384), Expect = 2e-36 Identities = 81/193 (41%), Positives = 125/193 (64%), Gaps = 2/193 (1%) Query: 183 ESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCR 242 + + R+SLPVF +EE++ I ++V++I GETGSGKTTQIPQ+L ++ + N + Sbjct: 389 KESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNK-GMK 447 Query: 243 IFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMA 302 I CTQPRR+AA++VA RVA E ++G +GY IR E S +T+L + T+G+LLR ++ Sbjct: 448 IACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLS 507 Query: 303 GDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGS 362 + L++ + V+VDE HER +D L ++D+ + P LK++++SA +D F +F Sbjct: 508 -EPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDD 566 Query: 363 CPVIYIQGRPFEV 375 PV I GR F V Sbjct: 567 APVFRIPGRRFPV 579 >gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapiens] Length = 703 Score = 159 bits (402), Expect = 2e-38 Identities = 123/426 (28%), Positives = 206/426 (48%), Gaps = 40/426 (9%) Query: 623 GAVLIFLPGYDEIVGLRDRILFDDKRFADN--THRYQVFMLHSNMQTSDQKKVLKNPPAG 680 G VL FL G +E+ + ++ + A +V +++ + + +Q KV + Sbjct: 275 GDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRS 334 Query: 681 VRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRA 740 VRK+I++TN+AETSIT++ +V+VID G VK ++++ + L +V +S+ASA QR GR Sbjct: 335 VRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRG 394 Query: 741 GRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEP 800 GR R G C+RL++ F + + PE+ R L + L K L N F+ P Sbjct: 395 GRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFM----SP 450 Query: 801 PPALIVRNAVQMLKTIDAMDTWEDLTE-LGYHLADLPVEPHLGKMVLCAVVLKCLDPILT 859 PPA + A+++L + +D LTE LG +A+ P+ P KM+L + C IL+ Sbjct: 451 PPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILS 510 Query: 860 IACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAF 919 IA + ++ FV+P +QK A+ ++F A DH+ +L ++A+ K D + Sbjct: 511 IAAMMQIQNIFVVP--PNQKSHAIRVHRKF-AVEEGDHLTMLNIYEAFIKHNKDS---KW 564 Query: 920 CEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGM 979 C+++FL+ + +R QL L R GD +V +V+G Sbjct: 565 CQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSEGDP----------DLVLRCIVSGF 614 Query: 980 YPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPPANGQAAAIKALPTDWLIYDE 1039 + N T + ++ HPASVL Y + PP W+IY+E Sbjct: 615 FANAARFHSTGAYRTIRDDHELHIHPASVL----YAEKPPR-------------WVIYNE 657 Query: 1040 MTRAHR 1045 + + + Sbjct: 658 VIQTSK 663 Score = 122 bits (306), Expect = 2e-27 Identities = 74/203 (36%), Positives = 119/203 (58%), Gaps = 13/203 (6%) Query: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPR 249 RQ LPVF+ + I+ +I+ + V+IVGETG GK+TQIPQ+L + + + TQPR Sbjct: 51 RQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGW-TAEGRVVGVTQPR 109 Query: 250 RLAAIAVAERVAAERRERIGQTIGYQIRLESRVSP-KTLLTFCTNGVLLRTLMAGDSTLS 308 R+AA+ VA RVA ER +G +GY IR + T + F T+G+L+R +M D L+ Sbjct: 110 RVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMV-DPLLT 168 Query: 309 TVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFG------- 361 + +++DE HER ++D + L+ + +K L+LI++SA LD + F +F Sbjct: 169 KYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDP 228 Query: 362 ---SCPVIYIQGRPFEVKEMFLE 381 +C ++ ++GR F V +L+ Sbjct: 229 ARDTCVILTVEGRTFPVDIFYLQ 251 >gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens] Length = 1227 Score = 157 bits (396), Expect = 9e-38 Identities = 82/191 (42%), Positives = 128/191 (67%), Gaps = 5/191 (2%) Query: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKN-GIPCRIFCTQP 248 RQ LP+F Q+E++ II++N +V++VGETGSGKTTQ+ Q+L +D + + G+ I CTQP Sbjct: 529 RQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGM---IGCTQP 585 Query: 249 RRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLS 308 RR+AA++VA+RV+ E +G+ +GY IR E S TL+ + T+G+LLR + ++ L Sbjct: 586 RRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLR-EADLD 644 Query: 309 TVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYI 368 + +I+DE HER +D L LR+++ + LKLI++SA +D F +FG+ P+ +I Sbjct: 645 HYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHI 704 Query: 369 QGRPFEVKEMF 379 GR F V +F Sbjct: 705 PGRTFPVDILF 715 Score = 150 bits (378), Expect = 1e-35 Identities = 102/319 (31%), Positives = 169/319 (52%), Gaps = 12/319 (3%) Query: 623 GAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVR 682 G +LIF+PG ++I D+I+ + +N V ++S + + Q K+ + P GVR Sbjct: 741 GDILIFMPGQEDIEVTSDQIV-EHLEELENAPALAVLPIYSQLPSDLQAKIFQKAPDGVR 799 Query: 683 KIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGR 742 K I++TNIAETS+TV+ ++FVIDSG K K F+ + L++ IS+A+A QR GRAGR Sbjct: 800 KCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGR 859 Query: 743 CRPGICFRLFSRLRFQN-MLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPP 801 PG CFRL+++ ++N +L PE+ R L + L K L + F+ +PP Sbjct: 860 TGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFM----DPP 915 Query: 802 PALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIA 861 P + N++ L + A+D LT G + + P++P L KM++ + + C IL I Sbjct: 916 PEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIV 975 Query: 862 CTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCE 921 L+ F P ++ + R++F A SDH+ L + W +++ + +C Sbjct: 976 SMLSVPAIFYRPKGREEESDQI--REKF-AVPESDHLTYLNVYLQW---KNNNYSTIWCN 1029 Query: 922 KNFLSQATMEIIIGMRTQL 940 +F+ M + +R QL Sbjct: 1030 DHFIHAKAMRKVREVRAQL 1048 >gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapiens] Length = 779 Score = 150 bits (378), Expect = 1e-35 Identities = 115/407 (28%), Positives = 195/407 (47%), Gaps = 27/407 (6%) Query: 622 AGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQ--------VFMLHSNMQTSDQKKV 673 AG +L+FL G EI + +LF D + Q + + +M T Q+++ Sbjct: 272 AGDILVFLTGQFEIEKSCE-LLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRI 330 Query: 674 LKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASA 733 PP G+RK ++STNI+ TS+T++ + +V+D G VK+ + + + +L++V ISK+ A Sbjct: 331 FLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEA 390 Query: 734 IQRKGRAGRCRPGICFRLFSR-LRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIAD 792 +QR GRAGR G CFR++S+ Q M + PE+ R L + L K LA + Sbjct: 391 LQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFP 450 Query: 793 FLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLK 852 +L +PP ++ A++ L DA+D +T LG + + P+ PHL V+ A L Sbjct: 451 YL----DPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLD 506 Query: 853 CLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFT--AGAFSDHMALLRAFQAWQKA 910 C D +L IA L+ + F+ P ++ A + AG F+D L F ++ Sbjct: 507 CEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIF---EQC 563 Query: 911 RSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAV 970 +S G ++C+K+++ + + QL +R + + D V Sbjct: 564 KSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIR-----KLKQQSDFPKETFEGPKHEV 618 Query: 971 VKAALVAGMYPNLVH--VDRENLVLTGPKEKKVRFHPASVLSQPQYK 1015 ++ L AG + N+ V R + G + V HP+S L + + K Sbjct: 619 LRRCLCAGYFKNVARRSVGRTFCTVDG-RGSPVHIHPSSALHEQETK 664 Score = 132 bits (332), Expect = 2e-30 Identities = 71/194 (36%), Positives = 126/194 (64%), Gaps = 10/194 (5%) Query: 192 SLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCF-KNGIPCRIFCTQPRR 250 + P+ +++++I++ +++N +++ G TGSGKTTQ+P++L + F ++G+ I TQPR+ Sbjct: 52 TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM---IGVTQPRK 108 Query: 251 LAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTV 310 +AAI+VA+RVA E + +G +GYQ+R + S +T + + T+G LL+ ++ GD L+ Sbjct: 109 VAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHIL-GDPNLTKF 167 Query: 311 THVIVDEVHERDRFSDFLLTKLRDLLQ-KHPT----LKLILSSAALDVNLFIRYFGSCPV 365 + +I+DE HER +D L L+ L Q K P LK+++ SA +++ +FG+CP+ Sbjct: 168 SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227 Query: 366 IYIQGRPFEVKEMF 379 I GR + V+E F Sbjct: 228 FDIPGRLYPVREKF 241 >gi|166851804 tudor domain containing 9 [Homo sapiens] Length = 1382 Score = 149 bits (377), Expect = 1e-35 Identities = 109/306 (35%), Positives = 154/306 (50%), Gaps = 23/306 (7%) Query: 621 DAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTH-RYQVFMLHSNMQTSDQKKVLKNPPA 679 + +VL+FLPG EI + + + H R QV+ LHS++ +Q V +P Sbjct: 384 ERSSVLVFLPGLGEINYMHELL-------TSLVHKRLQVYPLHSSVALEEQNNVFLSPVP 436 Query: 680 GVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGR 739 G RKIILSTNIAE+S+TV DV +VID + D L++ W SK S QRKGR Sbjct: 437 GYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGR 496 Query: 740 AGRCRPGICFRLFSRLRFQNML-EFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAP 798 AGR G C+RL + + N + + PE+LR PL L KLL + P A L A Sbjct: 497 AGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLL-DMGEPRA-LLATAL 554 Query: 799 EPPPALIVRNAVQMLKTIDAMDTW----------EDLTELGYHLADLPVEPHLGKMVLCA 848 PP + + +LK + A+ +LT LG LA LPV LGK+++ Sbjct: 555 SPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQQLGKLIVLG 614 Query: 849 VVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQ 908 V CLD L IA L+ ++ F +P + Q + F+ + SD +AL+ AF+ W+ Sbjct: 615 HVFGCLDECLIIAAALSLKNFFAMPFR--QHLDGYRNKVNFSGSSKSDCIALVEAFKTWK 672 Query: 909 KARSDG 914 R G Sbjct: 673 ACRQTG 678 Score = 139 bits (351), Expect = 1e-32 Identities = 76/200 (38%), Positives = 118/200 (59%), Gaps = 10/200 (5%) Query: 193 LPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLA 252 LP+ +EE+V +I+ N VV+I G TGSGK+TQ+PQ++LD + C I TQPR++ Sbjct: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYCSIVVTQPRKIG 191 Query: 253 AIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTH 312 A ++A ++ ER +G +GYQ+ LE + T L + T GVLL+ +++ S L TH Sbjct: 192 ASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKS-LMEFTH 250 Query: 313 VIVDEVHERDRFSDFLLTKLRDLLQKHPT-LKLILSSAALDVNLFIRYF--------GSC 363 +I+DEVHER DFLL +R LL+ + +K++L SA + F YF Sbjct: 251 IIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNPA 310 Query: 364 PVIYIQGRPFEVKEMFLEDI 383 + ++G+P V+E +L D+ Sbjct: 311 YIFEVEGKPHSVEEYYLNDL 330 >gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapiens] Length = 1157 Score = 136 bits (342), Expect = 2e-31 Identities = 102/322 (31%), Positives = 151/322 (46%), Gaps = 43/322 (13%) Query: 658 VFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDAL 717 V L+S + Q +V K PP G R +++TN+AETS+T+ + +V+D GKVK++ +D + Sbjct: 590 VLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRV 649 Query: 718 NFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELC 777 V+ ++ W+S+ASA QR GRAGR PG C+RL+S F + +F PE+ R P+++L Sbjct: 650 TGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLI 709 Query: 778 LHTKLL---APVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWE----------- 823 L K L +N P P PP + A ++L + A+ + Sbjct: 710 LQMKALNVEKVINFPF-------PTPPSVEALLAAEELLIALGALQPPQKAERVKQLQEN 762 Query: 824 ----DLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPF--------- 870 +T LG +A PV P KM+ + CL +TI ++ R+ F Sbjct: 763 RLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAAS 822 Query: 871 -VLPTQASQKRAAMLCRKRFTAG-----AFSDHMALLRAFQAWQKARSDGWERAFCEKNF 924 T+ KRA + KR AG D M LL A A + A FCE N Sbjct: 823 DEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYA---SCTPQFCEANG 879 Query: 925 LSQATMEIIIGMRTQLLGQLRA 946 L M I +R QL + A Sbjct: 880 LRYKAMMEIRRLRGQLTTAVNA 901 Score = 117 bits (293), Expect = 8e-26 Identities = 78/211 (36%), Positives = 121/211 (57%), Gaps = 12/211 (5%) Query: 177 IPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFK 236 IPV R E R LP+ +++ I++ + E+ +V++ GETGSGKTTQ+PQFL + F Sbjct: 237 IPVNRSP-EMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFS 295 Query: 237 NGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVL 296 + I T+PRR+AA+A+++RVA E + + YQIR E V+ +T + F T+GVL Sbjct: 296 SE-DSIIGVTEPRRVAAVAMSQRVAKE-MNLSQRVVSYQIRYEGNVTEETRIKFMTDGVL 353 Query: 297 LRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLL----QKHPTLKLILSSAALD 352 L+ + D L VI+DE HER ++D L+ L ++ +++ LKL++ SA L Sbjct: 354 LKEIQK-DFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLR 412 Query: 353 VNLFIR----YFGSCPVIYIQGRPFEVKEMF 379 V F + + PVI ++ R F V F Sbjct: 413 VEDFTQNPRLFAKPPPVIKVESRQFPVTVHF 443 >gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapiens] Length = 452 Score = 132 bits (332), Expect = 2e-30 Identities = 71/194 (36%), Positives = 126/194 (64%), Gaps = 10/194 (5%) Query: 192 SLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCF-KNGIPCRIFCTQPRR 250 + P+ +++++I++ +++N +++ G TGSGKTTQ+P++L + F ++G+ I TQPR+ Sbjct: 52 TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM---IGVTQPRK 108 Query: 251 LAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTV 310 +AAI+VA+RVA E + +G +GYQ+R + S +T + + T+G LL+ ++ GD L+ Sbjct: 109 VAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHIL-GDPNLTKF 167 Query: 311 THVIVDEVHERDRFSDFLLTKLRDLLQ-KHPT----LKLILSSAALDVNLFIRYFGSCPV 365 + +I+DE HER +D L L+ L Q K P LK+++ SA +++ +FG+CP+ Sbjct: 168 SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227 Query: 366 IYIQGRPFEVKEMF 379 I GR + V+E F Sbjct: 228 FDIPGRLYPVREKF 241 Score = 95.5 bits (236), Expect = 3e-19 Identities = 61/172 (35%), Positives = 97/172 (56%), Gaps = 10/172 (5%) Query: 622 AGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFML--------HSNMQTSDQKKV 673 AG +L+FL G EI + +LF D + Q +L + +M T Q+++ Sbjct: 272 AGDILVFLTGQFEIEKSCE-LLFQMAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRI 330 Query: 674 LKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASA 733 PP G+RK ++STNI+ TS+T++ + +V+D G VK+ + + + +L++V ISK+ A Sbjct: 331 FLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEA 390 Query: 734 IQRKGRAGRCRPGICFRLFSR-LRFQNMLEFQTPELLRMPLQELCLHTKLLA 784 +QR GRAGR G CFR++S+ Q M + PE+ R L + L K LA Sbjct: 391 LQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLA 442 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 130 bits (328), Expect = 7e-30 Identities = 76/180 (42%), Positives = 104/180 (57%), Gaps = 7/180 (3%) Query: 1246 DRSDQSSLKSTDSSSYPSPCASPSPPSSGKGSKSPSPRPNMPVRYFIMKSSNLRNLEISQ 1305 DRS S+ +S S S S + K S R+F++KS+N N+ +++ Sbjct: 313 DRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLIKSNNHENVSLAK 372 Query: 1306 QKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQ-DW---- 1360 KG+WST P NE+KLN AF + V L+FSV+ SG FQGF+R+SSE S W Sbjct: 373 AKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPA 432 Query: 1361 --GSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPLVGEQLLQLW 1418 + LGGVFK++WI + LPF + HL NPWN++K V+I RDGQE+E G QL L+ Sbjct: 433 GMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLF 492 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 127 bits (320), Expect = 6e-29 Identities = 66/137 (48%), Positives = 91/137 (66%), Gaps = 7/137 (5%) Query: 1289 RYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRM 1348 R+F++KS+N N+ +++ KG+WST P NE+KLN AF + V L+FSV+ SG FQGF+R+ Sbjct: 338 RFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARL 397 Query: 1349 SSEIGREKSQ-DW------GSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISR 1401 SSE S W + LGGVFK++WI + LPF + HL NPWN++K V+I R Sbjct: 398 SSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGR 457 Query: 1402 DGQELEPLVGEQLLQLW 1418 DGQE+E G QL L+ Sbjct: 458 DGQEIELECGTQLCLLF 474 >gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo sapiens] Length = 743 Score = 108 bits (269), Expect = 5e-23 Identities = 60/191 (31%), Positives = 115/191 (60%), Gaps = 9/191 (4%) Query: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDC----FKNGIPCRIFC 245 R+ LP+++++ ++ + +N++V++ G+ GK+ Q+PQ+ + C +++G + C Sbjct: 59 REDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHG---GVIC 115 Query: 246 TQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDS 305 TQ + + +A RVA E IG +GY I E+ + +T+L +CT+ +L R +M+ + Sbjct: 116 TQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMS-NP 174 Query: 306 TLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPV 365 L + +I+D++HER +D LL L+D+L P LKLI++S+ ++ Y+G+ PV Sbjct: 175 FLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPV 234 Query: 366 IYIQGR-PFEV 375 I ++ + P EV Sbjct: 235 IEVKNKHPVEV 245 Score = 91.3 bits (225), Expect = 6e-18 Identities = 101/426 (23%), Positives = 188/426 (44%), Gaps = 24/426 (5%) Query: 602 EKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFML 661 +K + I+ L++ I HS + G +++FL +I + + + + + V L Sbjct: 252 QKDSFESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETV-YQGSNLNPDLGELVVVPL 310 Query: 662 HSNMQTSDQK---KVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALN 718 + + S K + K R+++L+T+ E I N V FVID G + K ++ Sbjct: 311 YPKEKCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRI 370 Query: 719 FVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSR-LRFQNMLEFQTPELLRMPLQELC 777 L M IS++ A RK G G F L++ ++M + E+ L + Sbjct: 371 RANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMV 430 Query: 778 LHTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPV 837 L K + DF+ + P P +++ A++ L + A+D +L+E G +++ P+ Sbjct: 431 LFMKRIDIAGLGHCDFMNR---PAPESLMQ-ALEDLDYLAALDNDGNLSEFGIIMSEFPL 486 Query: 838 EPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDH 897 +P L K +L + C+D +LTIA + + F +++ AA+ C K F DH Sbjct: 487 DPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHVPHGAEE-AALTCWKTFLHPE-GDH 544 Query: 898 MALLRAFQAWQ----KARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRAR 953 L+ ++A+Q + S+ +C FL+ + + + +R +LL ++ A Sbjct: 545 FTLISIYKAYQDTTLNSSSEYCVEKWCRDYFLNCSALRMADVIRAELLEIIKRIELPYA- 603 Query: 954 GGGDIRDVNTNSENWAVVKAALVAGMYPNLVH-VDRENLVLTGPKEKKVRFHPASVLSQP 1012 + EN +K AL++G + + VD L ++ + HP S S Sbjct: 604 -----EPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSGYSIT 658 Query: 1013 QYKKIP 1018 KK+P Sbjct: 659 --KKMP 662 >gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo sapiens] Length = 717 Score = 85.9 bits (211), Expect = 3e-16 Identities = 65/191 (34%), Positives = 104/191 (54%), Gaps = 8/191 (4%) Query: 190 RQSLPVFEKQEEIVKIIKENK--VVLIVGETGSGKTTQIPQFLLDDCFKNGIPC-RIFCT 246 RQ+LP++ + ++ ++ N VVL+ GE GSGK+TQIPQ+ + G ++ T Sbjct: 42 RQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQKGQVTVT 101 Query: 247 QPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDST 306 QP LAA ++A RVA E +G +GY I E P TLL FC + +LL+ + + T Sbjct: 102 QPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRLLLQEVASTRGT 161 Query: 307 LSTVTHVIVDEVHERDRFSDFLLTKLRDL-LQKHP--TLKLILSSAALDVNLFIRYFGSC 363 +++DE ER SD L L+D L+K P ++++ AL+ L ++G+ Sbjct: 162 -GAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEPKL-RAFWGNP 219 Query: 364 PVIYIQGRPFE 374 P+++I P E Sbjct: 220 PIVHIPREPGE 230 Score = 84.0 bits (206), Expect = 1e-15 Identities = 117/504 (23%), Positives = 209/504 (41%), Gaps = 71/504 (14%) Query: 616 ICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLK 675 +C G VL+FLP +EI + + + + +V LH + + Q V + Sbjct: 255 LCRKELPGDVLVFLPSEEEISLCCESLSREVESLLLQGLPPRVLPLHPDCGRAVQA-VYE 313 Query: 676 NPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQ 735 + A RK++++ +A+ S ++ + VIDSG ++ + ISK A Sbjct: 314 DMDA--RKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEA 371 Query: 736 RKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQE--------LCLHTKLLAPVN 787 R+ RA PG C L+ + + LE + P L + + E L ++ P Sbjct: 372 RRLRARGFPPGSCLCLYPK----SFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGE 427 Query: 788 CPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLC 847 C D +P P +++ A++ L + A+D DL++LG L++ P+ P L K +L Sbjct: 428 CHFLD------QPAPEALMQ-ALEDLDYLAALDDDGDLSDLGVILSEFPLAPELAKALLA 480 Query: 848 AVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAF--- 904 + C+D +LT+A L F P ++++ A +R DH +L++ + Sbjct: 481 SCEFDCVDEMLTLAAMLTAAPGFTRPPLSAEEAAL----RRALEHTDGDHSSLIQVYEAF 536 Query: 905 ------QAWQKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDI 958 +AW +AR W A C+ + L +E++ R +L L A G Sbjct: 537 IQSGADEAWCQARGLNW-AALCQAHKLRGELLELM--QRIELPLSLPAFG---------- 583 Query: 959 RDVNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIP 1018 + +N ++ ALV+G + + D + TG H A + S Y+ Sbjct: 584 -----SEQNRRDLQKALVSGYFLKVAR-DTDG---TGNYLLLTHKHVAQLSSYCCYR--- 631 Query: 1019 PANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPV--TILVFCGPARLASNALQE 1076 + A P W++Y T I+ C S V+ + +LV P SN Sbjct: 632 -----SRRAPARPPPWVLYHNFT----ISKDNCLSIVSEIQPQMLVELAPPYFLSNLPPS 682 Query: 1077 PSSFRVDGIPNDSSDSEMEDKTTA 1100 S ++ + +DS K+++ Sbjct: 683 ESRDLLNQLREGMADSTAGSKSSS 706 >gi|31377750 YTH domain family, member 1 [Homo sapiens] Length = 559 Score = 71.2 bits (173), Expect = 7e-12 Identities = 48/133 (36%), Positives = 69/133 (51%), Gaps = 4/133 (3%) Query: 1289 RYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSI---VYLVFSVQGSGHFQGF 1345 R FI+KS + ++ S + IW +T ++L+ AF S VYL+FSV GSGHF G Sbjct: 390 RVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGV 449 Query: 1346 SRMSSEIGREKSQD-WGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQ 1404 + M S + S W G F V+WI + +P H+ NDNK V SRD Q Sbjct: 450 AEMKSPVDYGTSAGVWSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQ 509 Query: 1405 ELEPLVGEQLLQL 1417 E+ +Q+L++ Sbjct: 510 EVPLEKAKQVLKI 522 >gi|116235460 YTH domain family, member 3 [Homo sapiens] Length = 585 Score = 67.4 bits (163), Expect = 9e-11 Identities = 44/133 (33%), Positives = 68/133 (51%), Gaps = 4/133 (3%) Query: 1289 RYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWE---SSIVYLVFSVQGSGHFQGF 1345 R FI+KS + ++ S + IW +T ++L+ A+ +YL+FSV GSGHF G Sbjct: 417 RVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKGPLYLLFSVNGSGHFCGV 476 Query: 1346 SRMSSEIGREKSQD-WGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQ 1404 + M S + W G F+V+WI + +P H+ NDNK V SRD Q Sbjct: 477 AEMKSVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQ 536 Query: 1405 ELEPLVGEQLLQL 1417 E+ +Q+L++ Sbjct: 537 EVPLEKAKQVLKI 549 >gi|116812575 high glucose-regulated protein 8 [Homo sapiens] Length = 579 Score = 66.2 bits (160), Expect = 2e-10 Identities = 44/133 (33%), Positives = 67/133 (50%), Gaps = 4/133 (3%) Query: 1289 RYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESS---IVYLVFSVQGSGHFQGF 1345 R FI+KS + ++ S + IW +T ++L+ A+ + VYL+FSV GSGHF G Sbjct: 411 RVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGV 470 Query: 1346 SRMSSEIGREKSQD-WGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQ 1404 + M S + W G F V WI + +P H+ N+NK V SRD Q Sbjct: 471 AEMKSAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQ 530 Query: 1405 ELEPLVGEQLLQL 1417 E+ +Q+L++ Sbjct: 531 EVPLEKAKQVLKI 543 >gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit 12A isoform b [Homo sapiens] Length = 943 Score = 48.9 bits (115), Expect = 3e-05 Identities = 29/94 (30%), Positives = 45/94 (47%) Query: 500 DYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLL 559 D RH+++ TAL VAA +G+ ++ LI G +V+ K +GW L A H+G+ E +L Sbjct: 105 DVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRIL 164 Query: 560 ESYSASLEFGNLDESSLVQTNGSDLSAEDRELLK 593 +E N + D+ EL K Sbjct: 165 VDNLCDMEMVNKVGQTAFDVADEDILGYLEELQK 198 >gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit 12A isoform a [Homo sapiens] Length = 1030 Score = 48.9 bits (115), Expect = 3e-05 Identities = 29/94 (30%), Positives = 45/94 (47%) Query: 500 DYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLL 559 D RH+++ TAL VAA +G+ ++ LI G +V+ K +GW L A H+G+ E +L Sbjct: 192 DVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRIL 251 Query: 560 ESYSASLEFGNLDESSLVQTNGSDLSAEDRELLK 593 +E N + D+ EL K Sbjct: 252 VDNLCDMEMVNKVGQTAFDVADEDILGYLEELQK 285 Score = 31.6 bits (70), Expect = 5.7 Identities = 37/161 (22%), Positives = 61/161 (37%), Gaps = 37/161 (22%) Query: 399 KEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLDDGGDAVFSQLTEKDV 458 K ++K+ L W ++ + P +RQ+T + DDG AVF Sbjct: 2 KMADAKQKRNEQLKRWIGSETDLEPPVVKRQKTKVK-------FDDG--AVF-------- 44 Query: 459 NCLEPWLIKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRG 518 + AC S D D ++ H ++Y + + TAL A Sbjct: 45 ----------LAACSSG-----DTDEVLKLLH----RGADINYANVD-GLTALHQACIDD 84 Query: 519 FASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLL 559 V+ L+ GAN++ + GW+ L A G +I + L Sbjct: 85 NVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFL 125 >gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit 12A isoform a [Homo sapiens] Length = 1030 Score = 48.9 bits (115), Expect = 3e-05 Identities = 29/94 (30%), Positives = 45/94 (47%) Query: 500 DYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLL 559 D RH+++ TAL VAA +G+ ++ LI G +V+ K +GW L A H+G+ E +L Sbjct: 192 DVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRIL 251 Query: 560 ESYSASLEFGNLDESSLVQTNGSDLSAEDRELLK 593 +E N + D+ EL K Sbjct: 252 VDNLCDMEMVNKVGQTAFDVADEDILGYLEELQK 285 Score = 31.6 bits (70), Expect = 5.7 Identities = 37/161 (22%), Positives = 61/161 (37%), Gaps = 37/161 (22%) Query: 399 KEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLDDGGDAVFSQLTEKDV 458 K ++K+ L W ++ + P +RQ+T + DDG AVF Sbjct: 2 KMADAKQKRNEQLKRWIGSETDLEPPVVKRQKTKVK-------FDDG--AVF-------- 44 Query: 459 NCLEPWLIKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRG 518 + AC S D D ++ H ++Y + + TAL A Sbjct: 45 ----------LAACSSG-----DTDEVLKLLH----RGADINYANVD-GLTALHQACIDD 84 Query: 519 FASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLL 559 V+ L+ GAN++ + GW+ L A G +I + L Sbjct: 85 NVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFL 125 >gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapiens] Length = 1771 Score = 48.5 bits (114), Expect = 5e-05 Identities = 23/57 (40%), Positives = 36/57 (63%) Query: 509 TALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSAS 565 TAL+ A+ G VE+L+ G N+ + GW AL WA + G+T++V+LL S+ A+ Sbjct: 73 TALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGAN 129 Score = 38.1 bits (87), Expect = 0.061 Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 1/76 (1%) Query: 492 ILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFG 551 +L + VD R+ E T LM+AA +G V++LI GAN + + + W AL A G Sbjct: 24 LLEKCKDVDERN-ECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEG 82 Query: 552 QTEIVDLLESYSASLE 567 IV+ L +LE Sbjct: 83 HVHIVEELLKCGVNLE 98 Score = 35.4 bits (80), Expect = 0.40 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 2/71 (2%) Query: 492 ILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFG 551 +L VD + S TAL+VA G+ V++++ NV+ +G AL A G Sbjct: 189 LLAMGADVD-QEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEG 247 Query: 552 QTEIV-DLLES 561 TEIV DLL++ Sbjct: 248 HTEIVQDLLDA 258 Score = 32.7 bits (73), Expect = 2.6 Identities = 21/61 (34%), Positives = 28/61 (45%) Query: 507 SATALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSASL 566 S ++ AAGRG A V L+ GA V+ G L WA G E V L + A + Sbjct: 137 SVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADV 196 Query: 567 E 567 + Sbjct: 197 D 197 Score = 30.8 bits (68), Expect = 9.8 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 1/91 (1%) Query: 485 FAQVFHLILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNGWMAL 544 + Q IL N +V+ + + TALM+A+ G V+ L+ G V+ +G L Sbjct: 215 YTQSVKEILKRNPNVNLTDKDGN-TALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVL 273 Query: 545 DWAKHFGQTEIVDLLESYSASLEFGNLDESS 575 A G EIV L A ++ D + Sbjct: 274 IGAVRGGHVEIVRALLQKYADIDIRGQDNKT 304 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.133 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 55,171,140 Number of Sequences: 37866 Number of extensions: 2599105 Number of successful extensions: 19078 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 193 Number of HSP's successfully gapped in prelim test: 181 Number of HSP's that attempted gapping in prelim test: 16916 Number of HSP's gapped (non-prelim): 1935 length of query: 1430 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1315 effective length of database: 13,892,928 effective search space: 18269200320 effective search space used: 18269200320 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.