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Search of human proteins with 124517695
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
(1121 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 2172 0.0
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 1922 0.0
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 1868 0.0
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 1608 0.0
gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 862 0.0
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 612 e-175
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 610 e-174
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 565 e-161
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 535 e-152
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 535 e-152
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 532 e-151
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 531 e-150
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 374 e-103
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 369 e-101
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 322 1e-87
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 249 8e-66
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 249 8e-66
gi|169217530 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 224 4e-58
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 217 6e-56
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 217 6e-56
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 217 6e-56
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 214 4e-55
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 207 6e-53
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 207 6e-53
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 207 6e-53
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 196 1e-49
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 196 1e-49
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 196 1e-49
gi|239754871 PREDICTED: similar to Coiled-coil domain-containing... 125 3e-28
gi|239749410 PREDICTED: similar to Coiled-coil domain-containing... 125 3e-28
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 2172 bits (5627), Expect = 0.0
Identities = 1121/1121 (100%), Positives = 1121/1121 (100%)
Query: 1 MCFLEMCMESLQKIMPVRLRIELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQ 60
MCFLEMCMESLQKIMPVRLRIELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQ
Sbjct: 1 MCFLEMCMESLQKIMPVRLRIELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQ 60
Query: 61 KQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGG 120
KQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGG
Sbjct: 61 KQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGG 120
Query: 121 KSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNI 180
KSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNI
Sbjct: 121 KSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNI 180
Query: 181 ATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSV 240
ATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSV
Sbjct: 181 ATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSV 240
Query: 241 KEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQ 300
KEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQ
Sbjct: 241 KEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQ 300
Query: 301 PSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQS 360
PSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQS
Sbjct: 301 PSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQS 360
Query: 361 GTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAR 420
GTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAR
Sbjct: 361 GTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAR 420
Query: 421 EIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENK 480
EIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENK
Sbjct: 421 EIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENK 480
Query: 481 DSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQS 540
DSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQS
Sbjct: 481 DSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQS 540
Query: 541 SQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLR 600
SQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLR
Sbjct: 541 SQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLR 600
Query: 601 VKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQ 660
VKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQ
Sbjct: 601 VKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQ 660
Query: 661 KVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLM 720
KVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLM
Sbjct: 661 KVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLM 720
Query: 721 QDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLA 780
QDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLA
Sbjct: 721 QDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLA 780
Query: 781 ALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVD 840
ALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVD
Sbjct: 781 ALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVD 840
Query: 841 KCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQS 900
KCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQS
Sbjct: 841 KCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQS 900
Query: 901 QMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQAR 960
QMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQAR
Sbjct: 901 QMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQAR 960
Query: 961 CDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDD 1020
CDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDD
Sbjct: 961 CDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDD 1020
Query: 1021 VLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGD 1080
VLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGD
Sbjct: 1021 VLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGD 1080
Query: 1081 TQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES 1121
TQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES
Sbjct: 1081 TQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES 1121
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 1922 bits (4979), Expect = 0.0
Identities = 1014/1133 (89%), Positives = 1042/1133 (91%), Gaps = 34/1133 (3%)
Query: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVS------------------------ 58
+S QKQ AEKATSD+KDSVSNIATEIKEG SGTVS
Sbjct: 298 VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI 357
Query: 59 ----------SQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVS 108
SQKQP KATSD+ DS NIATEIK+G Q GTVS QKQ A K ++ S
Sbjct: 358 TGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDS 417
Query: 109 LLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALK 168
+ NIAT I G KSGTVSSQKQPA K +D+ DS LN ATEIKDG + TVSSQKQ ALK
Sbjct: 418 VSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALK 477
Query: 169 ATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVS 228
ATTDEE SVS IATEIKDGEKSGTVSS+KKPALKATSDEKDSFSNITREKKDGEISRTVS
Sbjct: 478 ATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVS 537
Query: 229 SQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKD 288
SQKPPALKATS +EDSVL+IARE+KDGEKSRTVS EQPPGLKATRDEKDSLLNIARGKK
Sbjct: 538 SQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKY 597
Query: 289 GEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVS 348
GEKTRRVSSHKQP+LKATSDKE+SVPNMATETKDEQISGTVS QKQPALKATSDKKDSVS
Sbjct: 598 GEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVS 657
Query: 349 NIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTT 408
NIPTEIKDGQQSGTVSSQKQ AWKATSVKKDSVSNIATEIKDGQIRGTVSSQR+PALK T
Sbjct: 658 NIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKAT 717
Query: 409 GDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPE 468
GDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGG KSGTEYPE
Sbjct: 718 GDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPE 777
Query: 469 NLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQI 528
NL TLKATIENK+SVLNTATKMK+VQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQI
Sbjct: 778 NLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQI 837
Query: 529 HSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRL 588
HSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK TFCL KRL
Sbjct: 838 HSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRL 897
Query: 589 IKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQE 648
+LKDNHCEQLRVKIRKLKNKASVLQKR+SEKEEIKSQLKHE LELEKELCSLRFAIQQE
Sbjct: 898 TELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQE 957
Query: 649 KKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETD 708
KKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETD
Sbjct: 958 KKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETD 1017
Query: 709 EKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETL 768
EKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRN ETL
Sbjct: 1018 EKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETL 1077
Query: 769 AKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSK 828
A+TIACYSGQLAALTDENTTLRSKLEKQRES QRLETEMQSYRCRLNAA CDHDQSHSSK
Sbjct: 1078 AETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSK 1137
Query: 829 RDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVF 888
RDQELAFQGTVDKC HLQENLNSHVLILSLQLSKAESK RVL+TELHYTGEALKEKALVF
Sbjct: 1138 RDQELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVF 1197
Query: 889 EHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKAD 948
EHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKAD
Sbjct: 1198 EHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKAD 1257
Query: 949 NQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAERE 1008
NQEKAILNIQARCDARV+NLQAECRKHRLLLEEDNKMLVNELNHSKEK+CQYEKEKAERE
Sbjct: 1258 NQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAERE 1317
Query: 1009 VAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLT 1068
VAVRQLQQK+DDVLNK SATKALLDASSRHC YLENGMQDSRKKLDQMRSQFQEIQDQLT
Sbjct: 1318 VAVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLT 1377
Query: 1069 ATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES 1121
ATIRCTKEMEGD QKLEVE+VMMRKIIKKQD+QIER EKILQHSSLMLQVFES
Sbjct: 1378 ATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVFES 1430
Score = 402 bits (1033), Expect = e-111
Identities = 380/1198 (31%), Positives = 554/1198 (46%), Gaps = 179/1198 (14%)
Query: 43 NIATEIKEGPISG---TVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQ 99
N+ E K P +G VS ++ P T + D +S + S S ++
Sbjct: 179 NVDKEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLS 238
Query: 100 KVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTV 159
+ K+ A R G VSSQKQPA K SD DS N ATEIK+G GTV
Sbjct: 239 TLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTV 298
Query: 160 SSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKK 219
SSQKQ A KAT+DE+ SVSNIATEIK+G++SGTVS QK+ A K +K S NI
Sbjct: 299 SSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIT 358
Query: 220 DGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSL 279
G S TVSSQK P KATS K DS LNIA E KDG + TVS ++ P LKAT DE+DS+
Sbjct: 359 GGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSV 418
Query: 280 LNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKA 339
NIA KDGEK+ VSS KQP+LKAT+D+EDSV N+ATE KD + S TVS QKQPALKA
Sbjct: 419 SNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKA 478
Query: 340 TSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSS 399
T+D++DSVS I TEIKDG++SGTVSS+K+PA KATS +KDS SNI E KDG+I TVSS
Sbjct: 479 TTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSS 538
Query: 400 QRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGG 459
Q+ PALK T DE+DSV +IARE KDGEKS TVS ++ K +K SLLNIA G
Sbjct: 539 QKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYG 598
Query: 460 GK----------------------------------SGTEYPENLRTLKATIENKDSVLN 485
K SGT + LKAT + KDSV N
Sbjct: 599 EKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSN 658
Query: 486 TATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKN-------------QIHSRD 532
T++K+ Q S ++A + + + N ++K+ + +
Sbjct: 659 IPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATG 718
Query: 533 DLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKC--KDCVHLLKIKNTFC-LWKRLI 589
D D + + +DG+ + Q K K V LL I WK
Sbjct: 719 DEKDSVSNIAREIKDGEK-----SGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGT 773
Query: 590 KLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEK 649
+ +N L ++NK SVL K+ S + LE+ A + E+
Sbjct: 774 EYPEN----LPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEM---------ASEGEQ 820
Query: 650 KKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGG----NNSNQVS 705
K+ E +V+ ++ ++ + ++S++ + G N N +
Sbjct: 821 KRLEEYENNQPQVKNQIHSRDD-----------LDDIIQSSQTVSEDGDSLCCNCKNVIL 869
Query: 706 ETDEKE----DLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKAL 761
D+ E D +H ++ + RL + +K+ + E+ +K +K K LQK L
Sbjct: 870 LIDQHEMKCKDCVHLLKIKKTFCLCKRLTE--LKDNHCEQLRVK-IRKLKNKASVLQKRL 926
Query: 762 KRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAA---- 817
E ++ + L E +LR ++++++ R+ +E Q R +L
Sbjct: 927 SEKEEIKSQ----LKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQY 982
Query: 818 RCDHDQSHSSK-----RDQELAFQG--------TVDKCRHLQENLNSHVLILSLQLSKAE 864
R + D + K + EL G T +K L EN I L+L K
Sbjct: 983 RIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDT 1042
Query: 865 SKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGY-------NTME 917
K++ L+ + E +K K E +Q LK+ + + + Y T+
Sbjct: 1043 IKNQNLEKKYLKDFEIVKRK---HEDLQKALKRNEETLAETIACYSGQLAALTDENTTLR 1099
Query: 918 KCIEKQERF------------CQL--------------KKQNMLLQQQLDDARNKADNQE 951
+EKQ C+L + Q + Q +D + +N
Sbjct: 1100 SKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLN 1159
Query: 952 KAILNIQ---ARCDARVQNLQAE-------CRKHRLLLEEDNKMLVNELNHSKEKECQYE 1001
+L + ++ +++ + L+ E ++ L+ E L + + K+ E Y+
Sbjct: 1160 SHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYK 1219
Query: 1002 K---------EKAEREVAVRQ----LQQKRDDVLNKG-SATKALLDASSRHCTYLENGMQ 1047
EK ER +++ LQQ+ DD NK + KA+L+ +R +EN
Sbjct: 1220 SGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQA 1279
Query: 1048 DSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVE-HVMMRKIIKKQDDQIER 1104
+ RK R +E L + +KE + +K + E V +R++ +KQDD + +
Sbjct: 1280 ECRKH----RLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNK 1333
Score = 303 bits (777), Expect = 5e-82
Identities = 323/1157 (27%), Positives = 505/1157 (43%), Gaps = 162/1157 (14%)
Query: 57 VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 116
VSSQKQPA K TSD+ DSVSN ATEIK+ Q+SGTV P + + ++ T
Sbjct: 20 VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTED 79
Query: 117 MGGGKSGTVSSQKQPASKTASDKT-------------------DSALNTATEIKDGLQCG 157
+S +S P K S ++ D T+ K L+
Sbjct: 80 EFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYLLDRFAQAVTKDKFALESE 139
Query: 158 -----------TVSSQKQQALKATTDEEGSVSNIATEIKDGEKSG----------TVSSQ 196
T+S Q + L A + + + E ++ +K G VS +
Sbjct: 140 NISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNVDKEGKALPATGQKANVSPE 199
Query: 197 KKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGE 256
+ P T + D S D S SS++PP T + D A +KD
Sbjct: 200 QPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSP 259
Query: 257 KSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNM 316
VS ++ P KAT D+KDS+ NIA K+G + VSS KQP+ KATSD++DSV N+
Sbjct: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 319
Query: 317 ATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSV 376
ATE K+ Q SGTVS QKQ A K KK S+ NI T I G +SGTVSSQKQP KATS
Sbjct: 320 ATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSD 379
Query: 377 KKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQ 436
K DS NIATEIKDG GTVSSQ++PALK T DE+DSVSNIA EIKDGEKSGTVS QKQ
Sbjct: 380 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 439
Query: 437 SAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTS 496
A K ++ S+LNIAT I G KS T + LKAT + +DSV AT++K+ + S
Sbjct: 440 PALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKS 499
Query: 497 TPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSR--------------DDLDDII---- 538
+ A + + + N + K+ SR D+ D ++
Sbjct: 500 GTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAR 559
Query: 539 -----QSSQTVSED---GDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIK 590
+ S+TVS + G + K+ +L I + + + + K +
Sbjct: 560 EEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPAL---KATS 616
Query: 591 LKDNHCEQLRVKIRKLKNKASVLQ------KRISEKEEIKSQLKHEILELEKE---LCSL 641
K+N + + + + +V K S+K++ S + EI + ++
Sbjct: 617 DKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQK 676
Query: 642 RFAIQQEKKKRRNVEELHQKVRE-KLRITEEQYRIEA-DVTKPIKPALKSAEVELKTGGN 699
+ A + K+ +V + ++++ ++R T R A T K ++ + E+K G
Sbjct: 677 QLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEK 736
Query: 700 NSNQVSETDEKEDLLHENRLMQDEIA---------------RLRLEKDTIKNQNL---EK 741
+ + + ++ + ++ IA L K TI+N+N
Sbjct: 737 SGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTA 796
Query: 742 KYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQ 801
+KD + +DL+ A E K + Y + ++ + R L+ +S Q
Sbjct: 797 TKMKDVQTSTPAEQDLEMA----SEGEQKRLEEYENNQPQVKNQIHS-RDDLDDIIQSSQ 851
Query: 802 RLETEMQSYRCRLNAARCDHDQSHSSKRD--QELAFQGTVDKCRHLQENLNSHVLILSLQ 859
+ + S C DQ +D L + T C+ L E ++H L ++
Sbjct: 852 TVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVK 911
Query: 860 LSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC 919
+ K ++K+ VL+ + L EK E ++S+LK +
Sbjct: 912 IRKLKNKASVLQ-------KRLSEK----EEIKSQLK--------------------HET 940
Query: 920 IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKA-----ILNIQARCDARVQNLQAECRK 974
+E ++ C L+ +QQ+ RN + +K I Q R +A V K
Sbjct: 941 LELEKELCSLR---FAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALK 997
Query: 975 HRLLLEEDNKMLVNELNHSKEKE-CQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLD 1033
+ + N+++ + EKE +E + E+A +L+ ++D + N+ K L D
Sbjct: 998 SAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIA--RLRLEKDTIKNQNLEKKYLKD 1055
Query: 1034 ASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRK 1093
+ ++K + ++ + ++ L TI C G L E+ +R
Sbjct: 1056 ------------FEIVKRKHEDLQKALKRNEETLAETIAC---YSGQLAALTDENTTLRS 1100
Query: 1094 IIKKQDDQIERLEKILQ 1110
++KQ + +RLE +Q
Sbjct: 1101 KLEKQRESGQRLETEMQ 1117
Score = 96.7 bits (239), Expect = 1e-19
Identities = 166/817 (20%), Positives = 311/817 (38%), Gaps = 124/817 (15%)
Query: 18 RLRIELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 77
++R +S Q+Q A KAT D+KDSVSNIA EIK+G SGTVS QKQ A+K +K S+ N
Sbjct: 701 QIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLN 760
Query: 78 IATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTAS 137
IAT I G +SGT P+ K + K S+LN AT++ S + AS+
Sbjct: 761 IATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQ 820
Query: 138 DKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQK 197
+ + N ++K+ + + D + + + T +DG+ + K
Sbjct: 821 KRLEEYENNQPQVKN-------------QIHSRDDLDDIIQSSQTVSEDGD--SLCCNCK 865
Query: 198 KPALKATSDE---KDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAR--EK 252
L E KD ++ + KK + + ++ K + VK + N A +K
Sbjct: 866 NVILLIDQHEMKCKDCV-HLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQK 924
Query: 253 KDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDS 312
+ EK S + L+ ++ I + KK + + L+ T ++
Sbjct: 925 RLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQ--- 981
Query: 313 VPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWK 372
+I V+ +PALK+ + + N ++ + + +K+
Sbjct: 982 ----------YRIEADVTKPIKPALKSAEVELKTGGNNSNQVSE-------TDEKEDLLH 1024
Query: 373 ATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVS 432
+ +D ++ + EKD++ N E K + V
Sbjct: 1025 ENRLMQDEIARLRL------------------------EKDTIKNQNLEKKYLKDFEIVK 1060
Query: 433 PQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKE 492
+ + QK + N TL TI L T
Sbjct: 1061 RKHEDLQKAL------------------------KRNEETLAETIACYSGQLAALT---- 1092
Query: 493 VQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLC 552
+T LE E Q+ E ++ + ++ + D + + + C
Sbjct: 1093 -DENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKC 1151
Query: 553 C----NCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKN 608
C N + +L++ K + +L+ + + +K K E ++ ++++ ++
Sbjct: 1152 CHLQENLNSHVLILSLQLSKAESKFRVLETELHYT--GEALKEKALVFEHVQSELKQKQS 1209
Query: 609 KASVLQK----------RISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEL 658
+ ++K + EK+E QLK + + L+++L R ++K N++
Sbjct: 1210 QMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQAR 1269
Query: 659 HQKVREKLRITEEQYR--IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHE 716
E L+ ++R +E D + S E E E+E + +
Sbjct: 1270 CDARVENLQAECRKHRLLLEEDNKMLVNELNHSKE-------KKCQYEKEKAEREVAVRQ 1322
Query: 717 NRLMQDEIARLR-LEKDTIKNQNLEKKYLKD-FEIVKRKHEDLQKALKRNGETLAKTIAC 774
+ QD++ R K + + YL++ + ++K + ++ + + L TI C
Sbjct: 1323 LQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRC 1382
Query: 775 ---YSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 808
G L EN +R ++KQ E +R E +Q
Sbjct: 1383 TKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQ 1419
Score = 59.7 bits (143), Expect = 2e-08
Identities = 35/71 (49%), Positives = 41/71 (57%)
Query: 317 ATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSV 376
A E S VS QKQPALK TSDK DSVSN TEIKD Q+SGTV + +
Sbjct: 8 AASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLY 67
Query: 377 KKDSVSNIATE 387
+ D+V+ TE
Sbjct: 68 RPDAVAQPVTE 78
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 1868 bits (4840), Expect = 0.0
Identities = 1018/1262 (80%), Positives = 1044/1262 (82%), Gaps = 162/1262 (12%)
Query: 22 ELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 81
++S QKQ AEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE
Sbjct: 263 KVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 322
Query: 82 IKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTD 141
IK+GQQSGTVSPQKQSA KVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASK SDKTD
Sbjct: 323 IKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTD 382
Query: 142 SALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVS----------------------- 178
SALN ATEIKDGLQCGTVSSQKQ ALKATTDEE SVS
Sbjct: 383 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 442
Query: 179 -----------NIATEIKDGEKSGTVSSQK------------------------------ 197
NIATEIKDGEKSGTVSSQK
Sbjct: 443 KATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTV 502
Query: 198 ----KPALKATSDEKDSFSNITREKKDGEISR---------------------------- 225
KPALKATSDEKDSFSNITR KKDGEISR
Sbjct: 503 SSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENK 562
Query: 226 ------TVSSQKPPALKATSVKEDSVLNIAREKKDGEK---------------------- 257
TVSS+KPP LKA+S ++DSVLNIAR KKDGEK
Sbjct: 563 DGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSF 622
Query: 258 ------------SRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKA 305
SR VS ++PP LK T DE+DS+L IAR KDGEK+R VSS K P LKA
Sbjct: 623 SNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKA 682
Query: 306 TSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSS 365
TSD++DSV N+A KD + + TVS KQPALKA DK+DSV N+ TE KD Q SGTVS
Sbjct: 683 TSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSC 742
Query: 366 QKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDG 425
QKQPA KATS KKDSVSNI TEIKDGQ GTVSSQ++PA K T +KDSVSNIA EIKDG
Sbjct: 743 QKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDG 802
Query: 426 EKSGT--------------------------VSPQKQSAQKVIFKKKVSLLNIATRITGG 459
+ GT VSPQKQSAQKVIFKKKVSLLNIATRITGG
Sbjct: 803 QIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGG 862
Query: 460 GKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYEN 519
KSGTEYPENL TLKATIENK+SVLNTATKMK+VQTSTPAEQDLEMASEGEQKRLEEYEN
Sbjct: 863 WKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYEN 922
Query: 520 NQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK 579
NQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK
Sbjct: 923 NQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK 982
Query: 580 NTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELC 639
NTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELC
Sbjct: 983 NTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELC 1042
Query: 640 SLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGN 699
SLRFAIQQEKKKRRNVEE+HQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGN
Sbjct: 1043 SLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGN 1102
Query: 700 NSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQK 759
NSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQK
Sbjct: 1103 NSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQK 1162
Query: 760 ALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARC 819
ALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSY CRLNAARC
Sbjct: 1163 ALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARC 1222
Query: 820 DHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGE 879
DHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGE
Sbjct: 1223 DHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGE 1282
Query: 880 ALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQ 939
ALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQ
Sbjct: 1283 ALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQ 1342
Query: 940 LDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQ 999
LDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQ
Sbjct: 1343 LDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQ 1402
Query: 1000 YEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQ 1059
YEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQ
Sbjct: 1403 YEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQ 1462
Query: 1060 FQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVF 1119
FQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVF
Sbjct: 1463 FQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVF 1522
Query: 1120 ES 1121
ES
Sbjct: 1523 ES 1524
Score = 567 bits (1460), Expect = e-161
Identities = 459/1235 (37%), Positives = 619/1235 (50%), Gaps = 188/1235 (15%)
Query: 22 ELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 81
E S ++ T + D S A K+ P G VSSQKQPAEKATSD+KDSVSNIATE
Sbjct: 229 EESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATE 288
Query: 82 IKE----------------------------------GQQSGTVSPQKQSAQKVIFKKKV 107
IKE GQQSGTVSPQKQSA KVIFKKKV
Sbjct: 289 IKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKV 348
Query: 108 SLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQAL 167
SLLNIATRIMGGGKSGTVSSQKQPASK SDKTDSALN ATEIKDGLQCGTVSSQKQ AL
Sbjct: 349 SLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPAL 408
Query: 168 KATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTV 227
KATTDEE SVSNIATEIKDGEKSGTVSSQK+PALKAT+DEKDS SNI E KDGE S TV
Sbjct: 409 KATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTV 468
Query: 228 SSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKK 287
SSQKPPAL ATS +E SVL+IARE KDGEKSRTVS + P LKAT DEKDS NI RGKK
Sbjct: 469 SSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKK 528
Query: 288 DGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSV 347
DGE +R+VSS K P+LK TSD+EDSV +A E KD + S TVS +K P LKA+S +KDSV
Sbjct: 529 DGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSV 588
Query: 348 SNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKT 407
NI KDG+++ VSS+K+P+ +ATS +KDS SNI E KDG+I VSSQ+ PALK
Sbjct: 589 LNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKG 648
Query: 408 TGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYP 467
T DE+DSV IARE KDGEKS TVS +K K +K S+LNIA G K+ T
Sbjct: 649 TSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSS 708
Query: 468 ENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYEN-------- 519
LKA + +DSV N AT+ K+ Q S + A + + + N
Sbjct: 709 PKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDG 768
Query: 520 ---------NQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCK 570
QP K +D + +I + G + NV + DQ E K
Sbjct: 769 QQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNV--MFDQIEEKFT 826
Query: 571 DC-----VHLLKIKNTFCLWKRLIKLKD-------------NHCEQLRVKIRKLKNKASV 612
V K ++K+ + L + + E L ++NK SV
Sbjct: 827 SLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSV 886
Query: 613 LQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQ 672
L K+ S + LE+ A + E+K+ E +V+ ++ ++
Sbjct: 887 LNTATKMKDVQTSTPAEQDLEM---------ASEGEQKRLEEYENNQPQVKNQIHSRDD- 936
Query: 673 YRIEADVTKPIKPALKSAEVELKTGG----NNSNQVSETDEKE----DLLHENRLMQDEI 724
+ ++S++ + G N N + D+ E D +H ++
Sbjct: 937 ----------LDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFC 986
Query: 725 ARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTD 784
RL K +K+ + E+ +K +K K LQK + E ++ ++ L
Sbjct: 987 LWKRLIK--LKDNHCEQLRVK-IRKLKNKASVLQKRISEKEEIKSQ----LKHEILELEK 1039
Query: 785 ENTTLRSKLEKQRESRQRLETEMQSYRCRLNAA----RCDHDQSHSSK-----RDQELAF 835
E +LR ++++++ R+ +E Q R +L R + D + K + EL
Sbjct: 1040 ELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKT 1099
Query: 836 QG--------TVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALV 887
G T +K L EN I L+L K K++ L+ + E +K K
Sbjct: 1100 GGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRK--- 1156
Query: 888 FEHVQSELKQKQSQMKDIEKMYKSGY-------NTMEKCIEKQER------------FCQ 928
E +Q LK+ + Y T+ +EKQ C+
Sbjct: 1157 HEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCR 1216
Query: 929 L--------------KKQNMLLQQQLDDARNKADNQEKAILNIQ---ARCDARVQNLQAE 971
L + Q + Q +D R+ +N +L + ++ +++ + L+ E
Sbjct: 1217 LNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTE 1276
Query: 972 -------CRKHRLLLEEDNKMLVNELNHSKEKECQYEK---------EKAEREVAVRQ-- 1013
++ L+ E L + + K+ E Y+ EK ER +++
Sbjct: 1277 LHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQN 1336
Query: 1014 --LQQKRDDVLNKG-SATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTAT 1070
LQQ+ DD NK + KA+L+ +R ++N + RK R +E L
Sbjct: 1337 MLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKH----RLLLEEDNKMLVNE 1392
Query: 1071 IRCTKEMEGDTQKLEVE-HVMMRKIIKKQDDQIER 1104
+ +KE E +K + E V +R++ +K+DD + +
Sbjct: 1393 LNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNK 1427
Score = 352 bits (904), Expect = 9e-97
Identities = 340/1092 (31%), Positives = 509/1092 (46%), Gaps = 96/1092 (8%)
Query: 65 EKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGT 124
E E +V + Q VSP++ K + +I+TR +GG S T
Sbjct: 170 ENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRD---HISTRFLGGMDSLT 226
Query: 125 VS---SQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIA 181
S S++ P S + D + A KD G VSSQKQ A KAT+D++ SVSNIA
Sbjct: 227 SSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIA 286
Query: 182 TEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVK 241
TEIK+G SGTVSSQK+PA KATSDEKDS SNI E K G+ S TVS QK A K K
Sbjct: 287 TEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKK 346
Query: 242 EDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQP 301
+ S+LNIA G KS TVS ++ P KAT D+ DS LNIA KDG + VSS KQP
Sbjct: 347 KVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQP 406
Query: 302 SLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSG 361
+LKAT+D+EDSV N+ATE KD + SGTVS QKQPALKAT+D+KDSVSNI TEIKDG++SG
Sbjct: 407 ALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSG 466
Query: 362 TVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIARE 421
TVSSQK PA ATS ++ SV +IA E KDG+ TVSS+++PALK T DEKDS SNI R
Sbjct: 467 TVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRG 526
Query: 422 IKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKD 481
KDGE S VS QK K ++ S+L IA G KS T E LKA+ KD
Sbjct: 527 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKD 586
Query: 482 SVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSS 541
SVLN A K+ + + + + E + + N + K+ SR +
Sbjct: 587 SVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 646
Query: 542 QTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLR- 600
+ S++ DS +L E K + + + L K KD+ R
Sbjct: 647 KGTSDEEDS---------VLGIARENKDGEKSRTVSSEKPPGL-KATSDEKDSVLNIARG 696
Query: 601 ----VKIRKLKNKASVLQKRISEKEEIKSQLKHEILELE---KELCSLRFAIQQEKKKRR 653
K R + + K I +KE+ + E + + C + A++ K+
Sbjct: 697 KKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKD 756
Query: 654 NVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKED- 712
+V + ++++ + V+ +PA K+ V+ + N + ++ + +
Sbjct: 757 SVSNIPTEIKDGQQ--------SGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTG 808
Query: 713 -LLHENRLMQDEIARLRLEKDTIKNQNL---EKKYLKDFEIVKRKHEDLQKALKRNG--- 765
L + +M D+I EK T N++ +K I K+K L A + G
Sbjct: 809 ILEYTFNVMFDQIE----EKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWK 864
Query: 766 ---------ETLAKTIACYSGQLAALT-----DENTTLRSKLEKQRESRQRLETEMQSYR 811
TL TI + L T +T LE E Q+ E ++ +
Sbjct: 865 SGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQ 924
Query: 812 CRL-NAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVL 870
++ N D + Q ++ G C N + +L++ K + +L
Sbjct: 925 PQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCC-----NCKNVILLIDQHEMKCKDCVHLL 979
Query: 871 KTELHYT--GEALKEKALVFEHVQSELKQKQSQ----MKDIEKMYKSGYNTMEKCIEKQE 924
K + + +K K E ++ ++++ +++ K I + + + +E ++
Sbjct: 980 KIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEK 1039
Query: 925 RFCQLKKQNMLLQQQLDDARNKADNQEKA-----ILNIQARCDARVQNLQAECRKHRLLL 979
C L+ +QQ+ RN + +K I Q R +A V K +
Sbjct: 1040 ELCSLR---FAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVE 1096
Query: 980 EEDNKMLVNELNHSKEKE-CQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRH 1038
+ N+++ + EKE +E + E+A +L+ ++D + N+ K L D
Sbjct: 1097 LKTGGNNSNQVSETDEKEDLLHENRLMQDEIA--RLRLEKDTIKNQNLEKKYLKD----- 1149
Query: 1039 CTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQ 1098
+ ++K + ++ + + L TI C G L E+ +R ++KQ
Sbjct: 1150 -------FEIVKRKHEDLQKALKRNGETLAKTIAC---YSGQLAALTDENTTLRSKLEKQ 1199
Query: 1099 DDQIERLEKILQ 1110
+ +RLE +Q
Sbjct: 1200 RESRQRLETEMQ 1211
Score = 293 bits (750), Expect = 6e-79
Identities = 213/516 (41%), Positives = 267/516 (51%), Gaps = 40/516 (7%)
Query: 21 IELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIAT 80
+E+S QKQ A K TSD DSVSN ATEIK+ SGTV + + D+V+ T
Sbjct: 18 LEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVT 77
Query: 81 EIKEGQQSGTVSPQKQSAQKVIFKKKVS-------------------LLNIATRIMGGGK 121
E + +S +S +K+I + + T+ +
Sbjct: 78 ENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALE 137
Query: 122 SGTVSSQKQPASKTASDKTDSALNTATEI---------------KDGL------QCGTVS 160
S +S +T S ++ L+ A I K+G Q VS
Sbjct: 138 SENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVS 197
Query: 161 SQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKD 220
++ T + +S D S SS++ P T E D S +KD
Sbjct: 198 PEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKD 257
Query: 221 GEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLL 280
VSSQK PA KATS +DSV NIA E K+G S TVS ++ P KAT DEKDS+
Sbjct: 258 SPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVS 317
Query: 281 NIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKAT 340
NIA K G+++ VS KQ + K K+ S+ N+AT SGTVS QKQPA KAT
Sbjct: 318 NIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKAT 377
Query: 341 SDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQ 400
SDK DS NI TEIKDG Q GTVSSQKQPA KAT+ ++DSVSNIATEIKDG+ GTVSSQ
Sbjct: 378 SDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQ 437
Query: 401 RRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGG 460
++PALK T DEKDSVSNIA EIKDGEKSGTVS QK A ++ S+L+IA G
Sbjct: 438 KQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGE 497
Query: 461 KSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTS 496
KS T LKAT + KDS N K+ + S
Sbjct: 498 KSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEIS 533
Score = 255 bits (651), Expect = 2e-67
Identities = 206/524 (39%), Positives = 253/524 (48%), Gaps = 114/524 (21%)
Query: 107 VSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQA 166
V +L A + S VSSQKQPA K SDK DS NTATEIKD + GTV +Q
Sbjct: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQC 61
Query: 167 LKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEK------------------ 208
L + +V+ TE + +S +S P K S
Sbjct: 62 LNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYL 121
Query: 209 -DSFSN-ITREK---KDGEIS-------RTVSSQKPPALKAT---------SVKEDSVLN 247
D F+ +T++K + IS RT+S Q L A ++ ED N
Sbjct: 122 LDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQ--N 179
Query: 248 IAREKK----DGEKSRTVSFEQPP------------------GLKA-------------- 271
+ +E K G+K+ VS EQPP G+ +
Sbjct: 180 VDKEGKALPATGQKA-NVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLS 238
Query: 272 --TRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTV 329
T E D A +KD +VSS KQP+ KATSD +DSV N+ATE K+ ISGTV
Sbjct: 239 TLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTV 298
Query: 330 SCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAW------------------ 371
S QKQPA KATSD+KDSVSNI TEIK GQQSGTVS QKQ AW
Sbjct: 299 SSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIM 358
Query: 372 ----------------KATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSV 415
KATS K DS NIATEIKDG GTVSSQ++PALK T DE+DSV
Sbjct: 359 GGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSV 418
Query: 416 SNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKA 475
SNIA EIKDGEKSGTVS QKQ A K +K S+ NIAT I G KSGT + L A
Sbjct: 419 SNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTA 478
Query: 476 TIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYEN 519
T + + SVL+ A + K+ + S + A + + + N
Sbjct: 479 TSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSN 522
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 1608 bits (4163), Expect = 0.0
Identities = 827/862 (95%), Positives = 842/862 (97%)
Query: 260 TVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATE 319
+VS E+P GLKAT DEKDS+LNIARGKK GEKTRRVSSHKQP+LKATSDKE+SVPNMATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 320 TKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 379
TKDEQISGTVS QKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 380 SVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 439
SVSNIATEIKDGQIRGTVSSQR+PALK TGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 440 KVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPA 499
KVIFKKKVSLLNIATRITGG KSGTEYPENL TLKATIENK+SVLNTATKMK+VQTSTPA
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
Query: 500 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 559
EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI
Sbjct: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 306
Query: 560 LLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISE 619
LLIDQHEMKCKDCVHLLKIK TFCL KRL +LKDNHCEQLRVKIRKLKNKASVLQKR+SE
Sbjct: 307 LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSE 366
Query: 620 KEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 679
KEEIKSQLKHE LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV
Sbjct: 367 KEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 426
Query: 680 TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL 739
TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL
Sbjct: 427 TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL 486
Query: 740 EKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRES 799
EKKYLKDFEIVKRKHEDLQKALKRN ETLA+TIACYSGQLAALTDENTTLRSKLEKQRES
Sbjct: 487 EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRES 546
Query: 800 RQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQ 859
QRLETEMQSYRCRLNAA CDHDQSHSSKRDQELAFQGTVDKC HLQENLNSHVLILSLQ
Sbjct: 547 GQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQ 606
Query: 860 LSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC 919
LSKAESK RVL+TELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC
Sbjct: 607 LSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC 666
Query: 920 IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLL 979
IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARV+NLQAECRKHRLLL
Sbjct: 667 IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 726
Query: 980 EEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHC 1039
EEDNKMLVNEL HSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHC
Sbjct: 727 EEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHC 786
Query: 1040 TYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQD 1099
TYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGD QKLEVE+VMMRKIIKKQD
Sbjct: 787 TYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQD 846
Query: 1100 DQIERLEKILQHSSLMLQVFES 1121
+QIER EKILQHSSLMLQVFES
Sbjct: 847 EQIERFEKILQHSSLMLQVFES 868
Score = 254 bits (650), Expect = 2e-67
Identities = 273/946 (28%), Positives = 423/946 (44%), Gaps = 146/946 (15%)
Query: 124 TVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATE 183
+VSS+K K SD+ DS LN A K G + VSS KQ ALKAT+D+E SV N+ATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 184 IKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKED 243
KD + SGTVSSQK+PALKATSD+KDS SNI E KDG+ S TVSSQK PA KATSVK+D
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 244 SVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSL 303
SV NIA E KDG+ TVS ++ P LKAT DEKDS+ NIAR KDGEK+ VS KQ +
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 304 KATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTV 363
K K+ S+ N+AT SGT + P LKAT + K+SV N T++KD Q S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
Query: 364 SSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSV----SNIA 419
+ A + + + N ++K+ + +T ++ DS+ N+
Sbjct: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 306
Query: 420 REIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIEN 479
I E K + KK L T + + E LR ++N
Sbjct: 307 LLIDQHEMK-----CKDCVHLLKIKKTFCLCKRLTELK------DNHCEQLRVKIRKLKN 355
Query: 480 KDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQ 539
K SVL QKRL E E + Q+K++
Sbjct: 356 KASVL--------------------------QKRLSEKEEIKSQLKHE------------ 377
Query: 540 SSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHL-LKIKNTFCLWKRLIKLKDNHCEQ 598
E LC ++ I Q + K ++ L K++ + + +++ + +
Sbjct: 378 ----TLELEKELC----SLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKP 429
Query: 599 LRVKIRKLKNKASV---LQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNV 655
++ ++ + + ++SE +E K L HE ++ E+ LR ++++ K +N+
Sbjct: 430 IKPALKSAEVELKTGGNNSNQVSETDE-KEDLLHENRLMQDEIARLR--LEKDTIKNQNL 486
Query: 656 EELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSE-TDEKEDLL 714
E+ + K E ++ R D+ K +K ++ E +T S Q++ TDE L
Sbjct: 487 EKKYLKDFEIVK------RKHEDLQKALK---RNEETLAETIACYSGQLAALTDENTTL- 536
Query: 715 HENRLMQDEIARLRLEKDTIKNQNLE---KKYLKDFEIVKRKHEDLQKALKRNGETLAKT 771
R +LEK Q LE + Y H+ + + T
Sbjct: 537 -----------RSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 585
Query: 772 IACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ--SYRCRLNAARCDHDQS----- 824
+ L L +L K + LETE+ + A +H QS
Sbjct: 586 VDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQK 645
Query: 825 HSSKRDQELAFQ---GTVDKCRHLQE---NLNSHVLILSLQLSKAESKSRVLKTELHYTG 878
S +D E ++ T++KC QE L ++L QL A +K+
Sbjct: 646 QSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKA----------- 694
Query: 879 EALKEKALV---------FEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQL 929
+EKA++ E++Q+E ++ + +++ KM + + +E+ CQ
Sbjct: 695 -DNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKM------LVNELTHSKEKECQY 747
Query: 930 KKQN-------MLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKH----RLL 978
+K+ LQQ+ DD NK + KA+L+ +R ++N + RK R
Sbjct: 748 EKEKAEREVAVRQLQQKRDDVLNKG-SATKALLDASSRHCTYLENGMQDSRKKLDQMRSQ 806
Query: 979 LEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNK 1024
+E L + +KE E +K + E V +R++ +K+D+ + +
Sbjct: 807 FQEIQDQLTATIRCTKEMEGDAQKLEVE-NVMMRKIIKKQDEQIER 851
Score = 243 bits (621), Expect = 6e-64
Identities = 258/872 (29%), Positives = 383/872 (43%), Gaps = 132/872 (15%)
Query: 52 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLN 111
P +VSS+K KATSDEKDSV NIA K G+++ VS KQ A K K+ S+ N
Sbjct: 3 PFYFSVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPN 62
Query: 112 IATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATT 171
+AT SGTVSSQKQPA K SDK DS N TEIKDG Q GTVSSQKQ A KAT+
Sbjct: 63 MATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATS 122
Query: 172 DEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK 231
++ SVSNIATEIKDG+ GTVSSQ++PALKAT DEKDS SNI RE KDGE S TVS QK
Sbjct: 123 VKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 182
Query: 232 PPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKD--- 288
A K K+ S+LNIA G KS T E P LKAT + K+S+LN A KD
Sbjct: 183 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 242
Query: 289 -------------GEKTR-RVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQ 334
GE+ R + QP +K D + ++ ++ G C
Sbjct: 243 STPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNC 302
Query: 335 PALKATSDK-----KDSVSNIP-----------TEIKDGQQSGTVSSQKQPAWKATSVKK 378
+ D+ KD V + TE+KD ++ KA+ ++K
Sbjct: 303 KNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQK 362
Query: 379 DSVSNIATEIKDGQIRGTVSSQR-----RPALKTTGDEKDSVSNIAREIKDGEKSGTVSP 433
EIK T+ ++ R A++ ++ +V + ++++ EK
Sbjct: 363 RLSEK--EEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVR--EKLRITEE 418
Query: 434 QKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPE-------------------NLRTLK 474
Q + V K +L + + GG + + E LR K
Sbjct: 419 QYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEK 478
Query: 475 ATIENKDSVLNTATK-MKEVQTSTPAEQDLEMASEGEQKRLEE----YENNQPQVKNQIH 529
TI+N+ N K +K+ + +DL+ A + ++ L E Y + ++
Sbjct: 479 DTIKNQ----NLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENT 534
Query: 530 S-RDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKD-----------CVHLLK 577
+ R L+ +S Q + + S C + DQ +D C HL +
Sbjct: 535 TLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQE 594
Query: 578 IKNTFCLWKRLIKLKDNHCE--------QLRVKIRKLKNKASVLQKRISEKEEIKSQLK- 628
N+ L ++ L+ + E +L LK KA V + SE ++ +SQ+K
Sbjct: 595 NLNSHVL---ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKD 651
Query: 629 ------------HEILELEKELCSLR---FAIQQEKKKRRNVEELHQKVREKLRITEEQY 673
+ +E ++ C L+ +QQ+ RN + +K I Q
Sbjct: 652 IEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKA-----ILNIQA 706
Query: 674 RIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIA--RLRLEK 731
R +A V K + + N+++ + EKE +E + E+A +L+ ++
Sbjct: 707 RCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKE-CQYEKEKAEREVAVRQLQQKR 765
Query: 732 DTIKNQNLEKKYLKD------------FEIVKRKHEDLQKALKRNGETLAKTIAC---YS 776
D + N+ K L D + ++K + ++ + + L TI C
Sbjct: 766 DDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEME 825
Query: 777 GQLAALTDENTTLRSKLEKQRESRQRLETEMQ 808
G L EN +R ++KQ E +R E +Q
Sbjct: 826 GDAQKLEVENVMMRKIIKKQDEQIERFEKILQ 857
Score = 95.9 bits (237), Expect = 2e-19
Identities = 153/727 (21%), Positives = 290/727 (39%), Gaps = 98/727 (13%)
Query: 18 RLRIELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 77
++R +S Q+Q A KAT D+KDSVSNIA EIK+G SGTVS QKQ A+K +K S+ N
Sbjct: 139 QIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLN 198
Query: 78 IATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTAS 137
IAT I G +SGT P+ K + K S+LN AT++ S + AS+
Sbjct: 199 IATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQ 258
Query: 138 DKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQK 197
+ + N ++K+ + + D + + + T +DG+ + K
Sbjct: 259 KRLEEYENNQPQVKN-------------QIHSRDDLDDIIQSSQTVSEDGD--SLCCNCK 303
Query: 198 KPALKATSDE---KDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAR--EK 252
L E KD ++ + KK + + ++ K + VK + N A +K
Sbjct: 304 NVILLIDQHEMKCKDCV-HLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQK 362
Query: 253 KDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDS 312
+ EK S + L+ ++ I + KK + + L+ T ++
Sbjct: 363 RLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQ--- 419
Query: 313 VPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQK---QP 369
+I V+ +PALK+ + + N ++ + + + + Q
Sbjct: 420 ----------YRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQD 469
Query: 370 AWKATSVKKDSVSNIATE---IKDGQIRGTVSSQRRPALK----TTGDEKDSVSNIAREI 422
++KD++ N E +KD +I + ALK T + S +
Sbjct: 470 EIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAAL 529
Query: 423 KDGEKS--GTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATI--- 477
D + + Q++S Q++ + + + + +S + + + T+
Sbjct: 530 TDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKC 589
Query: 478 ----ENKDS-VLNTATKMKEVQTS-TPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSR 531
EN +S VL + ++ + ++ E +L E +++ +E+ Q ++K +
Sbjct: 590 CHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQM 649
Query: 532 DDLDDIIQSSQTVSE---DGDSLCCNCKNVILLIDQH------------------EMKCK 570
D++ + +S E + C K +L+ Q + +C
Sbjct: 650 KDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCD 709
Query: 571 DCVHLLKIKNTFCLWKRLIKLKDN--------HCEQLRVKIRKLKNKASVLQKRISEKEE 622
V L+ + C RL+ +DN H ++ + K K + V +++ +K +
Sbjct: 710 ARVENLQAE---CRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRD 766
Query: 623 ---IKSQLKHEILELEKELCS-LRFAIQQEKKK----RRNVEELHQKVREKLRITEEQYR 674
K +L+ C+ L +Q +KK R +E+ ++ +R T+E
Sbjct: 767 DVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKE--- 823
Query: 675 IEADVTK 681
+E D K
Sbjct: 824 MEGDAQK 830
>gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 475
Score = 862 bits (2226), Expect = 0.0
Identities = 436/443 (98%), Positives = 441/443 (99%)
Query: 571 DCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHE 630
DCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHE
Sbjct: 24 DCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHE 83
Query: 631 ILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA 690
ILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA
Sbjct: 84 ILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA 143
Query: 691 EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIV 750
EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRL+ DTIKNQNLEKKYLKDFEIV
Sbjct: 144 EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLDTDTIKNQNLEKKYLKDFEIV 203
Query: 751 KRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSY 810
KRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSY
Sbjct: 204 KRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSY 263
Query: 811 RCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVL 870
CRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVL
Sbjct: 264 HCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVL 323
Query: 871 KTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK 930
KTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK
Sbjct: 324 KTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK 383
Query: 931 KQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNEL 990
KQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNEL
Sbjct: 384 KQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNEL 443
Query: 991 NHSKEKECQYEKEKAEREVAVRQ 1013
NHSKEKECQYEKEKAEREV++++
Sbjct: 444 NHSKEKECQYEKEKAEREVSIKK 466
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 612 bits (1578), Expect = e-175
Identities = 348/504 (69%), Positives = 388/504 (76%), Gaps = 13/504 (2%)
Query: 57 VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 116
+S QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 117 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 176
MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 177 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 236
VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 237 ATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVS 296
ATSVKEDSVLNIAREKKDGEKSRTVSF+QPPGLKATRDEKDSLLNIARGKK+GEKTRRVS
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
Query: 297 SHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKD 356
S K+P+LKATSD++DS N+ KD +IS VS QK P LK TSD++DSV I E KD
Sbjct: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
Query: 357 GQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVS 416
G++S TVSS+K P KA+S +KDSV NIA K G+ VSS+++P+L+ T DEKDS S
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 417 NIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKAT 476
NI RE KDGE S VS QK A K ++ S+L IA G KS T E LKAT
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
Query: 477 IENKDSVLNTA-------------TKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQ 523
+ KDSVLN A ++ K +T E+D + E+K E+ Q
Sbjct: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
Query: 524 VKNQIHSRDDLDDIIQSSQTVSED 547
+ + + D +D + + T +D
Sbjct: 572 KQPALKAICDKEDSVPNMATEKKD 595
Score = 489 bits (1260), Expect = e-138
Identities = 302/510 (59%), Positives = 327/510 (64%), Gaps = 102/510 (20%)
Query: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
+S QKQ+A KAT+D++ SVSNIATEIK+G SGTVSSQK+PA KATSDEKDS SNI E
Sbjct: 194 VSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREK 253
Query: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGT------------------ 124
K+G+ S TVS QK A K K+ S+LNIA G KS T
Sbjct: 254 KDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDS 313
Query: 125 ----------------VSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALK 168
VSS+K+PA K SD+ DS N KDG VSSQK LK
Sbjct: 314 LLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLK 373
Query: 169 ATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKA------------------------- 203
T+DEE SV IA E KDGEKS TVSS+K P LKA
Sbjct: 374 GTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVS 433
Query: 204 ---------TSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKD 254
TSDEKDSFSNITREKKDGEISR VSSQKPPALK TS +EDSVL IARE KD
Sbjct: 434 SRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKD 493
Query: 255 GEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATS------- 307
GEKSRTVS E+PPGLKAT DEKDS+LNIARGKKDGEKTR VSS K+P+LKATS
Sbjct: 494 GEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVL 553
Query: 308 ---------------------------DKEDSVPNMATETKDEQISGTVSCQKQPALKAT 340
DKEDSVPNMATE KDEQISGTVS QKQPALKAT
Sbjct: 554 YIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKAT 613
Query: 341 SDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQ 400
SDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVS Q
Sbjct: 614 SDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQ 673
Query: 401 RRPALKTTGDEKDSVSNIAREIKDGEKSGT 430
++ A K +K S+ NIA I G KSGT
Sbjct: 674 KQSAQKVIFKKKVSLLNIATRITGGGKSGT 703
Score = 486 bits (1250), Expect = e-137
Identities = 320/612 (52%), Positives = 354/612 (57%), Gaps = 170/612 (27%)
Query: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVS------------------------ 58
+SPQKQ AEKATSD+KDSVSNIATEIKEG SGTVS
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 59 ----------SQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVS 108
SQKQPA K SD+ DS N ATEIK+G Q GTVS QKQ A K ++ S
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 109 LLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALK 168
+ NIAT I G KSGTVSSQK+PA K SD+ DS N E KDG TVSSQK ALK
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 169 ATTDEEGSVSNIATEIKDGEKSGTVS---------------------------------- 194
AT+ +E SV NIA E KDGEKS TVS
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
Query: 195 SQKKPALKATSDEKDSFSNITREKKDGEISR----------------------------- 225
S+KKPALKATSDEKDSFSNITR KKDGEISR
Sbjct: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
Query: 226 -----TVSSQKPPALKATSVKEDSVLNIAR------------------------------ 250
TVSS+KPP LKA+S ++DSVLNIAR
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 251 ----EKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKAT 306
EKKDGE SR VS ++PP LK T DE+DS+L IAR KDGEK+R VSS K P LKAT
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
Query: 307 SDKEDSVPNMATETKDEQISGTVSCQKQPALKATS------------------------- 341
SD++DSV N+A KD + + TVS +K+PALKATS
Sbjct: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
Query: 342 ---------DKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQ 392
DK+DSV N+ TE KD Q SGTVSSQKQPA KATS KKDSVSNI TEIKDGQ
Sbjct: 572 KQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 631
Query: 393 IRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNI 452
GTVSSQ++PA K T +KDSVSNIA EIKDG+ GTVSPQKQSAQKVIFKKKVSLLNI
Sbjct: 632 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNI 691
Query: 453 ATRITGGGKSGT 464
ATRITGGGKSGT
Sbjct: 692 ATRITGGGKSGT 703
Score = 319 bits (818), Expect = 8e-87
Identities = 194/341 (56%), Positives = 230/341 (67%)
Query: 22 ELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 81
++S QK K TSD++DSV IA E K+G S TVSS+K P KA+SDEKDSV NIA
Sbjct: 363 KVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARG 422
Query: 82 IKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTD 141
K G+++ VS +K+ + + +K S NI G S VSSQK PA K SD+ D
Sbjct: 423 KKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEED 482
Query: 142 SALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPAL 201
S L A E KDG + TVSS+K LKAT+DE+ SV NIA KDGEK+ TVSS+KKPAL
Sbjct: 483 SVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPAL 542
Query: 202 KATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTV 261
KATSDEKDS I REKKDGE SRTVSSQK PALKA KEDSV N+A EKKD + S TV
Sbjct: 543 KATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTV 602
Query: 262 SFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETK 321
S ++ P LKAT D+KDS+ NI KDG+++ VSS KQP+ KATS K+DSV N+ATE K
Sbjct: 603 SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIK 662
Query: 322 DEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGT 362
D QI GTVS QKQ A K KK S+ NI T I G +SGT
Sbjct: 663 DGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGT 703
Score = 33.9 bits (76), Expect = 0.89
Identities = 19/39 (48%), Positives = 24/39 (61%)
Query: 18 RLRIELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGT 56
++R +SPQKQ A+K K S+ NIAT I G SGT
Sbjct: 665 QIRGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGT 703
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 610 bits (1574), Expect = e-174
Identities = 352/541 (65%), Positives = 403/541 (74%), Gaps = 13/541 (2%)
Query: 22 ELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 81
++S QKQ AEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE
Sbjct: 263 KVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 322
Query: 82 IKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTD 141
IK+GQQSGTVSPQKQSA+KVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASK SDKTD
Sbjct: 323 IKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTD 382
Query: 142 SALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPAL 201
SALN ATEIKDGLQCGTVSSQKQ ALKATTDEE SVSNIATEIKDGEKSGTVSSQK+PAL
Sbjct: 383 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 442
Query: 202 KATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTV 261
KAT+DEKDS SNI E KDGE S TVSSQKPPAL ATS +E SVL+IARE KDGEKSRTV
Sbjct: 443 KATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTV 502
Query: 262 SFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETK 321
S + P KAT DEKDS NI RGKKDGE +R+VSS K P+LK TSD+EDSV +A E K
Sbjct: 503 SSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENK 562
Query: 322 DEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 381
D + S TVS +K P LKA+SD+KDSV NI K G+++ VSS+K+P+ +ATS +KDS
Sbjct: 563 DGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSF 622
Query: 382 SNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKV 441
SNI E KDG+I VSSQ+ PALK T DE+DSV IARE KDGEKS TVS +K K
Sbjct: 623 SNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKA 682
Query: 442 IFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTS----- 496
+K S+LNIA G K+ T + TLKAT + +DSVL+ A + K+ + S
Sbjct: 683 TSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSS 742
Query: 497 --------TPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 548
T AE+D + +K E+ + + K + + D D + +DG
Sbjct: 743 EKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDG 802
Query: 549 D 549
+
Sbjct: 803 E 803
Score = 538 bits (1387), Expect = e-153
Identities = 323/539 (59%), Positives = 369/539 (68%), Gaps = 75/539 (13%)
Query: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
+S QKQ A KAT+D++DSVSNIATEIK+G SGTVSSQKQPA KAT+DEKDSVSNIATEI
Sbjct: 400 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEI 459
Query: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
K+G++SGTVS QK A ++ S+L+IA G KS TVSS+K+PASK SD+ DS
Sbjct: 460 KDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDS 519
Query: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQ------ 196
N KDG VSSQK LK T+DEE SV IA E KDGEKS TVSS+
Sbjct: 520 FSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLK 579
Query: 197 ----------------------------KKPALKATSDEKDSFSNITREKKDGEISRTVS 228
KKP+L+ATSDEKDSFSNITREKKDGEISR VS
Sbjct: 580 ASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVS 639
Query: 229 SQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKD 288
SQKPPALK TS +EDSVL IARE KDGEKSRTVS E+PPGLKAT DEKDS+LNIARGKKD
Sbjct: 640 SQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKD 699
Query: 289 GEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQ---------------- 332
GEKTR VSS K P+LKATSD+EDSV ++A E KD + S TVS +
Sbjct: 700 GEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVL 759
Query: 333 ------------------KQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKAT 374
K+PALKATSD+KDSV I E KDG++S TVSSQKQPA KA
Sbjct: 760 NIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAI 819
Query: 375 SVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQ 434
K+DSV N+ATE KD QI GTVSSQ++PALK T D+KDSVSNI EIKDG++SGTVSPQ
Sbjct: 820 CDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQ 879
Query: 435 KQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEV 493
KQSAQKVIFKKKVSLLNIATRITGG KSGT ++ IE+ + + T K +V
Sbjct: 880 KQSAQKVIFKKKVSLLNIATRITGGWKSGT-------VIRQAIEHDECLCYTGIKPSDV 931
Score = 346 bits (888), Expect = 6e-95
Identities = 230/490 (46%), Positives = 288/490 (58%), Gaps = 6/490 (1%)
Query: 65 EKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGT 124
E E +V + Q VSP++ K + +I+TR +GG S T
Sbjct: 170 ENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRD---HISTRFLGGMDSLT 226
Query: 125 VS---SQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIA 181
S S++ P S + D + A KD G VSSQKQ A KAT+D++ SVSNIA
Sbjct: 227 SSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIA 286
Query: 182 TEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVK 241
TEIK+G SGTVSSQK+PA KATSDEKDS SNI E K G+ S TVS QK A K K
Sbjct: 287 TEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKK 346
Query: 242 EDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQP 301
+ S+LNIA G KS TVS ++ P KAT D+ DS LNIA KDG + VSS KQP
Sbjct: 347 KVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQP 406
Query: 302 SLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSG 361
+LKAT+D+EDSV N+ATE KD + SGTVS QKQPALKAT+D+KDSVSNI TEIKDG++SG
Sbjct: 407 ALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSG 466
Query: 362 TVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIARE 421
TVSSQK PA ATS ++ SV +IA E KDG+ TVSS+++PA K T DEKDS SNI R
Sbjct: 467 TVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRG 526
Query: 422 IKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKD 481
KDGE S VS QK K ++ S+L IA G KS T E LKA+ + KD
Sbjct: 527 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 586
Query: 482 SVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSS 541
SVLN A K + + + + E + + N + K+ SR +
Sbjct: 587 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 646
Query: 542 QTVSEDGDSL 551
+ S++ DS+
Sbjct: 647 KGTSDEEDSV 656
Score = 291 bits (746), Expect = 2e-78
Identities = 221/550 (40%), Positives = 284/550 (51%), Gaps = 74/550 (13%)
Query: 21 IELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIAT 80
+E+S QKQ A K TSD DSVSN ATEIK+ SGTV + + D+V+ T
Sbjct: 18 LEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVT 77
Query: 81 EIKEGQQSGTVSPQKQSAQKVIFKKKVS-------------------LLNIATRIMGGGK 121
E + +S +S +K+I + + T+ +
Sbjct: 78 ENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALE 137
Query: 122 SGTVSSQKQPASKTASDKTDSALNTATEI---KDGLQCGTVSSQKQQALKATTDEEGSVS 178
S +S +T S ++ L+ A I ++G + K+ T ++ +VS
Sbjct: 138 SENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVS 197
Query: 179 ---------------NIATEIKDGEKSGTVSSQKK--------------PALKATSDEKD 209
+I+T G S T S + P+ KA KD
Sbjct: 198 PEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKD 257
Query: 210 -----------------------SFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVL 246
S SNI E K+G IS TVSSQK PA KATS ++DSV
Sbjct: 258 SPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVS 317
Query: 247 NIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKAT 306
NIA E K G++S TVS ++ K +K SLLNIA G K+ VSS KQP+ KAT
Sbjct: 318 NIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKAT 377
Query: 307 SDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQ 366
SDK DS N+ATE KD GTVS QKQPALKAT+D++DSVSNI TEIKDG++SGTVSSQ
Sbjct: 378 SDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQ 437
Query: 367 KQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGE 426
KQPA KAT+ +KDSVSNIATEIKDG+ GTVSSQ+ PAL T DE+ SV +IARE KDGE
Sbjct: 438 KQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGE 497
Query: 427 KSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNT 486
KS TVS +K+ A K +K S NI G S + TLK T + +DSVL
Sbjct: 498 KSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGI 557
Query: 487 ATKMKEVQTS 496
A + K+ + S
Sbjct: 558 ARENKDGEKS 567
Score = 257 bits (656), Expect = 5e-68
Identities = 208/524 (39%), Positives = 255/524 (48%), Gaps = 114/524 (21%)
Query: 107 VSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQA 166
V +L A + S VSSQKQPA K SDK DS NTATEIKD + GTV +Q
Sbjct: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQC 61
Query: 167 LKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEK------------------ 208
L + +V+ TE + +S +S P K S
Sbjct: 62 LNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYL 121
Query: 209 -DSFSN-ITREK---KDGEIS-------RTVSSQKPPALKAT---------SVKEDSVLN 247
D F+ +T++K + IS RT+S Q L A ++ ED N
Sbjct: 122 LDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQ--N 179
Query: 248 IAREKK----DGEKSRTVSFEQPP------------------GLKA-------------- 271
+ +E K G+K+ VS EQPP G+ +
Sbjct: 180 VDKEGKALPATGQKA-NVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLS 238
Query: 272 --TRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTV 329
T E D A +KD +VSS KQP+ KATSD +DSV N+ATE K+ ISGTV
Sbjct: 239 TLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTV 298
Query: 330 SCQKQPALKATSDKKDSVSNIPTEIKDGQQ------------------------------ 359
S QKQPA KATSD+KDSVSNI TEIK GQQ
Sbjct: 299 SSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIM 358
Query: 360 ----SGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSV 415
SGTVSSQKQPA KATS K DS NIATEIKDG GTVSSQ++PALK T DE+DSV
Sbjct: 359 GGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSV 418
Query: 416 SNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKA 475
SNIA EIKDGEKSGTVS QKQ A K +K S+ NIAT I G KSGT + L A
Sbjct: 419 SNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTA 478
Query: 476 TIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYEN 519
T + + SVL+ A + K+ + S + AS+ + + N
Sbjct: 479 TSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSN 522
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 565 bits (1456), Expect = e-161
Identities = 358/926 (38%), Positives = 529/926 (57%), Gaps = 106/926 (11%)
Query: 250 REKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSS-HKQPSLKATSD 308
+EK G + F P + +R+ K + L R G + S + LK T +
Sbjct: 444 KEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNV--GMPVAHMESPERYLHLKPTIE 501
Query: 309 KEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQ 368
+DSVPN A KD Q S + A + +++ S +N P ++ ++
Sbjct: 502 MKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSENNQPQVEEERKKH-------- 553
Query: 369 PAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKS 428
+++ ++ I DG ++ D + ++ K GE
Sbjct: 554 ---------RNNEMEVSANIHDGAT-------------DDAEDDDDDDGLIQKRKSGETD 591
Query: 429 GTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTAT 488
P+K++ + + + + + TE + RT K ++ + V A+
Sbjct: 592 HQQFPRKENKEYASSGPALQMKEVKS---------TE--KEKRTSKESVNSP--VFGKAS 638
Query: 489 KMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 548
+ + L E E + ++ N + +VKNQI S DD+DD+ QSS+T SED
Sbjct: 639 LLTGGLLQVDDDSSLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDC 698
Query: 549 DSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKN 608
+ + KN +LLI+Q M+CKD V LLKI++ +RL++LK NHCE L VKI+K+++
Sbjct: 699 ELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMED 758
Query: 609 KASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRI 668
K +VLQ+ +SE +EIKSQL+H+ +E E+ELCSLRF++ QE++KRRN + L++K+RE+LR
Sbjct: 759 KVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRR 818
Query: 669 TEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET--------------------- 707
EEQYR E +V + ++ +L++ E+EL+T +N NQV +
Sbjct: 819 KEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGI 878
Query: 708 --------------------------DEKEDLLHENRLMQDEIARLRLEKDTIKNQN--L 739
+E++DL H+N ++Q+EIA LRLE DTIKNQN
Sbjct: 879 LTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEK 938
Query: 740 EKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRES 799
EKK +D +IVK K+EDLQK +K+N ETL +TI+ Y+G+L+ LT EN L SKLE +++S
Sbjct: 939 EKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQS 998
Query: 800 RQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL----- 854
++RLE E++SY RL AA D DQS +SKR+ ELAFQ D+C LQ+ +N V
Sbjct: 999 KERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDN 1058
Query: 855 --ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSG 912
ILS QL K ESK L+ E H+T +AL+EK L E VQ +L Q Q QMK++E+ Y++
Sbjct: 1059 NEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNE 1118
Query: 913 YNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNL 968
+ K I KQ ER QL+ +NMLL+QQLDDA NKADN+EK ++NIQ + A VQ L
Sbjct: 1119 QVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKL 1178
Query: 969 QAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSAT 1028
QAE K LLLEE NK L++E NH KE++ QYE EKAEREV VRQLQQ+ D L K S +
Sbjct: 1179 QAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMS 1238
Query: 1029 KALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEH 1088
+A L+ +SR+ LE+ QD +KKL Q+R+Q QE QD+ T +RC ++M+ QKLE ++
Sbjct: 1239 EASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDN 1298
Query: 1089 VMMRKIIKKQDDQIERLEKILQHSSL 1114
++ +KKQ D+IE L+K L +++L
Sbjct: 1299 AKLKVTVKKQMDKIEELQKNLLNANL 1324
Score = 107 bits (266), Expect = 8e-23
Identities = 167/730 (22%), Positives = 301/730 (41%), Gaps = 124/730 (16%)
Query: 454 TRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKR 513
TR G + E PE LK TIE KDSV N A MK+VQTS AE DLE+ASE EQ+R
Sbjct: 477 TRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQER 536
Query: 514 LEEYENNQPQVKNQ--------------IHSR--------DDLDDIIQSSQTVSEDGDSL 551
E ENNQPQV+ + IH DD D +IQ ++ D
Sbjct: 537 -EGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQF 595
Query: 552 -------------CCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHC-- 596
K V ++ + K+ V+ L L+++ D+
Sbjct: 596 PRKENKEYASSGPALQMKEV-KSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLS 654
Query: 597 ---EQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRR 653
E +K N+ + ++ +I +++ + E E C L + K
Sbjct: 655 EIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSS--ETASEDCELPHS--SYKNFML 710
Query: 654 NVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNS---------NQV 704
+E+L + ++ + + + Q +A ++ LK EL T ++
Sbjct: 711 LIEQLGMECKDSVSLLKIQ---DAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQREL 767
Query: 705 SETDE-KEDLLHENRLMQDEIARLR--LEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKA- 760
SET E K L H+ + E+ LR L ++ K +N + Y K E ++RK E +K
Sbjct: 768 SETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEV 827
Query: 761 -----LKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCR-- 813
L+ + +TL + L + E + +L +++ +R + + ++ +
Sbjct: 828 EVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQK 887
Query: 814 ---LNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVL 870
+ + + + SHS + +++L+ H L + +L L++ +++++
Sbjct: 888 EIEMAQKKMNSENSHSHEEEKDLS---------HKNSMLQEEIAMLRLEIDTIKNQNQE- 937
Query: 871 KTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE-RFCQL 929
KEK FE +LK + + +D++K K T+ + I + R L
Sbjct: 938 -----------KEKKC-FE----DLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVL 981
Query: 930 KKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNL-QAECRKHRLLLEEDNKMLVN 988
+N +L +L++ + + E + + +R A + + Q+E K L
Sbjct: 982 TAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKREL----------- 1030
Query: 989 ELNHSKEK-ECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQ 1047
EL + + EC ++K +V+ L+ + + + T++ L++ LE
Sbjct: 1031 ELAFQRARDECSRLQDKMNFDVS--NLKDNNEILSQQLFKTESKLNS-------LEIEFH 1081
Query: 1048 DSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEK 1107
+R L + + +Q L+ T KEME QK + E V + K I KQ+ ERL +
Sbjct: 1082 HTRDALREKTLGLERVQKDLSQTQCQMKEME---QKYQNEQVKVNKYIGKQESVEERLSQ 1138
Query: 1108 ILQHSSLMLQ 1117
+ + L+ Q
Sbjct: 1139 LQSENMLLRQ 1148
Score = 57.8 bits (138), Expect = 6e-08
Identities = 102/555 (18%), Positives = 218/555 (39%), Gaps = 69/555 (12%)
Query: 612 VLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQ------EKKKRRNVEELHQKVREK 665
++QKR S + + + + E KE S A+Q EK+KR + E ++ V K
Sbjct: 581 LIQKRKSGETDHQQFPRKE----NKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGK 636
Query: 666 --------LRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHEN 717
L++ ++ E D + +P K++ + K NQ+ D+ +DL +
Sbjct: 637 ASLLTGGLLQVDDDSSLSEIDEDEG-RPTKKTSNEKNKV----KNQIQSMDDVDDLTQSS 691
Query: 718 RLMQDEIARLRLEKDTIKNQNLEKKYL----KDFEIVKRKHEDLQKALKRNGETLAKTIA 773
++ L + KN L + L KD + K +D + +R E
Sbjct: 692 ETASEDC---ELPHSSYKNFMLLIEQLGMECKD-SVSLLKIQDAALSCERLLELKKNHCE 747
Query: 774 CYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQEL 833
+ ++ + D+ L+ +L + +E + +LE + + L + R +Q +R+ +
Sbjct: 748 LLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADT 807
Query: 834 AFQGTVDKCRHLQENLNSHVLI---LSLQLSKAESKSRVLKTELHYTGEALKEKALVFEH 890
++ ++ R +E V + L L L E + R +K+ L+ + +
Sbjct: 808 LYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSR 867
Query: 891 VQSE-------LKQKQSQMKDIE----KMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQ 939
Q+ L S+ K+IE KM ++ E+ + + L+++ +L+ +
Sbjct: 868 EQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLE 927
Query: 940 LDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEE--------------DNKM 985
+D +N+ +EK + ++LQ +++ L + +N M
Sbjct: 928 IDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAM 987
Query: 986 LVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENG 1045
L ++L + K+ + + E E + RD + + C+ L++
Sbjct: 988 LNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDK 1047
Query: 1046 MQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERL 1105
M + ++ + + QL T E LE+E R ++++ +ER+
Sbjct: 1048 MNFD---VSNLKDNNEILSQQLFKT-------ESKLNSLEIEFHHTRDALREKTLGLERV 1097
Query: 1106 EKILQHSSLMLQVFE 1120
+K L + ++ E
Sbjct: 1098 QKDLSQTQCQMKEME 1112
Score = 43.5 bits (101), Expect = 0.001
Identities = 152/804 (18%), Positives = 304/804 (37%), Gaps = 144/804 (17%)
Query: 19 LRIELSPQKQRAEKATSDDKDSVSNIATE-----IKEGPISGTVSSQKQPAEKATSDEKD 73
L +EL K + + D+ ++ E +++G ++ +S QK+ E A
Sbjct: 840 LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKE-IEMAQKKMNS 898
Query: 74 SVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKS-----GTVSSQ 128
S+ E K+ +S + Q+ I ++ + I + K V +
Sbjct: 899 ENSHSHEEEKD------LSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEK 952
Query: 129 KQPASKTASDKTDSALNTATEIKDGLQCGT---------VSSQKQQALKATTDEEGSVSN 179
+ KT ++ T ++ L T + ++KQ + + E S
Sbjct: 953 NEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSR 1012
Query: 180 IATEIKDGEKSGTVSSQKKPALKATSDE----KDSFS-NITREKKDGEISRTVSSQKPPA 234
+A I D ++S T + + A + DE +D + +++ K + EI +
Sbjct: 1013 LAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESK 1072
Query: 235 LKATSVKEDSVLNIAREKKDG----EKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDG- 289
L + ++ + REK G +K + + Q ++ + +N GK++
Sbjct: 1073 LNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESV 1132
Query: 290 -EKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDK----- 343
E+ ++ S + D + N + Q QK L+A S+K
Sbjct: 1133 EERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQK---LQAESEKQSLLL 1189
Query: 344 ----KDSVSNIPTEIKDGQ-QSGTVSSQKQPAWK------ATSVKKDSVSNIATEIKDGQ 392
K+ +S +K+ Q Q ++++ + A ++KK S+S + E+
Sbjct: 1190 EERNKELISEC-NHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEV---- 1244
Query: 393 IRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGT--------VSPQKQSAQKVIFK 444
S R T D K + I ++++ + T + KQ +K K
Sbjct: 1245 ----TSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAK 1300
Query: 445 KKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLE 504
KV++ +I E +NL + + K+ + K+ E++ S D E
Sbjct: 1301 LKVTVKKQMDKIE-------ELQKNLLNANLSEDEKEQL----KKLMELKQSLECNLDQE 1349
Query: 505 MASEGE---------------QKRLEEYENNQPQVKNQIH-SRDDLDDIIQSSQTVSEDG 548
M E +K+L EYEN + + S+ ++D I + +D
Sbjct: 1350 MKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDD- 1408
Query: 549 DSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLK--DNHCEQLRVKIRKL 606
L + E C+HL KN L + L+ +K CE+L+ +KL
Sbjct: 1409 ------------LTAELETAGSKCLHL-DTKNQI-LQEELLSMKTVQKKCEKLQKNKKKL 1454
Query: 607 KNKASVLQKRISE-----------KEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNV 655
+ + L+ I K+EI+ + + EI E KE + +Q + + N+
Sbjct: 1455 EQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKE---VNLFLQAQAASQENL 1511
Query: 656 EELHQ------KVREKLRITEEQYRI------EADVTKPIKPALKSAEV-ELKTGGNNSN 702
E+ + K + +LRI + + + + D K K + ELK + S+
Sbjct: 1512 EQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSS 1571
Query: 703 QVSETDEKEDLLHENRLMQDEIAR 726
++++T+E+ ++ L++ + +R
Sbjct: 1572 KLTKTNERLAEVNTKLLVEKQQSR 1595
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 535 bits (1379), Expect = e-152
Identities = 325/692 (46%), Positives = 435/692 (62%), Gaps = 37/692 (5%)
Query: 380 SVSNIATEIKDGQIRGTVS----SQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQK 435
+ + A K IRG +S ++RR +L+ + E+D E + E + PQ
Sbjct: 239 TAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298
Query: 436 QSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQT 495
+ K KK+ + Y +++ L I+N+ K
Sbjct: 299 EEKMKKCRNKKMEVSRNVH-----ADDSDNYNDDVDELIHKIKNR----------KPDNH 343
Query: 496 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 554
+P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + +
Sbjct: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397
Query: 555 CKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQ 614
+N +LLI Q M+CKD V L K KN R I+ + +CE+L+VK +K+KN SVLQ
Sbjct: 398 DENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457
Query: 615 KRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 674
K +SE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR
Sbjct: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517
Query: 675 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 733
+ +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT
Sbjct: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577
Query: 734 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRS 791
IK+QN E KY KD EI+K +EDL+K LKRN ETL KTI YS +L L DENT L S
Sbjct: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNS 637
Query: 792 KLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNS 851
+L+K+++S RLETEM+SYRCRL AA CDHDQ SSKRD +LAFQ TV++ HLQE+ NS
Sbjct: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697
Query: 852 HVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 911
H+ ILS QLSKAES S L+TELHY EALKEK L EH+Q L + Q +++DIE MY++
Sbjct: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757
Query: 912 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQN 967
+EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ V+
Sbjct: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817
Query: 968 LQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSA 1027
LQAECRK LEE+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK
Sbjct: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873
Query: 1028 TKALLDASSRHCTYLENGMQDSRKKLDQMRSQ 1059
+A+L+ SS LE+ Q +KKL QMRSQ
Sbjct: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 535 bits (1379), Expect = e-152
Identities = 325/692 (46%), Positives = 435/692 (62%), Gaps = 37/692 (5%)
Query: 380 SVSNIATEIKDGQIRGTVS----SQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQK 435
+ + A K IRG +S ++RR +L+ + E+D E + E + PQ
Sbjct: 239 TAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298
Query: 436 QSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQT 495
+ K KK+ + Y +++ L I+N+ K
Sbjct: 299 EEKMKKCRNKKMEVSRNVH-----ADDSDNYNDDVDELIHKIKNR----------KPDNH 343
Query: 496 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 554
+P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + +
Sbjct: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397
Query: 555 CKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQ 614
+N +LLI Q M+CKD V L K KN R I+ + +CE+L+VK +K+KN SVLQ
Sbjct: 398 DENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457
Query: 615 KRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 674
K +SE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR
Sbjct: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517
Query: 675 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 733
+ +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT
Sbjct: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577
Query: 734 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRS 791
IK+QN E KY KD EI+K +EDL+K LKRN ETL KTI YS +L L DENT L S
Sbjct: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNS 637
Query: 792 KLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNS 851
+L+K+++S RLETEM+SYRCRL AA CDHDQ SSKRD +LAFQ TV++ HLQE+ NS
Sbjct: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697
Query: 852 HVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 911
H+ ILS QLSKAES S L+TELHY EALKEK L EH+Q L + Q +++DIE MY++
Sbjct: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757
Query: 912 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQN 967
+EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ V+
Sbjct: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817
Query: 968 LQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSA 1027
LQAECRK LEE+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK
Sbjct: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873
Query: 1028 TKALLDASSRHCTYLENGMQDSRKKLDQMRSQ 1059
+A+L+ SS LE+ Q +KKL QMRSQ
Sbjct: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 532 bits (1370), Expect = e-151
Identities = 296/384 (77%), Positives = 320/384 (83%)
Query: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
+S QKQ AEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI
Sbjct: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
Query: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
KEGQQSGTVSPQKQSA KVIFKKKVSLLNIATRI GGGKSGTVSSQKQPASK SDKTDS
Sbjct: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
Query: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202
ALN ATEIKDGLQCGTVSSQKQ ALKATTDEE SVSNIATEIKDGEKSGTVSSQK+PALK
Sbjct: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
Query: 203 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 262
AT+DE+DS NI E KDGE S TVSSQK PALKAT+ +EDSV IA E KDGEKS TVS
Sbjct: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
Query: 263 FEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKD 322
+ P LKAT DEKDS NI R KKDGE +R V+S K LKATSD+EDSV N+A +D
Sbjct: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKED 307
Query: 323 EQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 382
+ + VS +K+PALKATSD+KDS SNI E KDG+ S TVSSQK PA KATS ++DSV
Sbjct: 308 GEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVL 367
Query: 383 NIATEIKDGQIRGTVSSQRRPALK 406
+IA E KDG+ TVSS++ P LK
Sbjct: 368 SIAREEKDGEKSRTVSSEQPPGLK 391
Score = 384 bits (986), Expect = e-106
Identities = 229/388 (59%), Positives = 270/388 (69%), Gaps = 3/388 (0%)
Query: 90 TVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATE 149
+VS QKQ A+K K S+ NIAT I G SGTVSSQKQPA K SD+ DS N ATE
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 150 IKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKD 209
IK+G Q GTVS QKQ A K ++ S+ NIAT I G KSGTVSSQK+PA KATSD+ D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 210 SFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGL 269
S NI E KDG TVSSQK PALKAT+ +EDSV NIA E KDGEKS TVS ++ P L
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 270 KATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTV 329
KAT DE+DS+LNIA KDGEK+ VSS KQP+LKAT+D+EDSV +ATE KD + SGTV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 330 SCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIK 389
S +K+PALKATSD+KDS SNI E KDG+ S TV+S+K KATS ++DSV NIA +
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 390 DGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSL 449
DG+ VSS+++PALK T DEKDS SNI RE KDGE S TVS QK A K ++ S+
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 450 LNIATRITGGGKSGT---EYPENLRTLK 474
L+IA G KS T E P L+ +K
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLKVMK 394
Score = 363 bits (932), Expect = e-100
Identities = 215/373 (57%), Positives = 260/373 (69%)
Query: 124 TVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATE 183
+VSSQKQPA K SD DS N ATEIK+G GTVSSQKQ A KAT+DE+ SVSNIATE
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 184 IKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKED 243
IK+G++SGTVS QK+ A K +K S NI G S TVSSQK PA KATS K D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 244 SVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSL 303
S LNIA E KDG + TVS ++ P LKAT DE+DS+ NIA KDGEK+ VSS KQP+L
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 304 KATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTV 363
KAT+D+EDSV N+ATE KD + S TVS QKQPALKAT+D++DSVS I TEIKDG++SGTV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 364 SSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIK 423
SS+K+PA KATS +KDS SNI E KDG+I TV+S++ LK T DE+DSV NIAR +
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 424 DGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSV 483
DGEK+ VS +K+ A K +K S NI G S T + LKAT + +DSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 484 LNTATKMKEVQTS 496
L+ A + K+ + S
Sbjct: 367 LSIAREEKDGEKS 379
Score = 344 bits (883), Expect = 2e-94
Identities = 201/341 (58%), Positives = 243/341 (71%)
Query: 156 CGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNIT 215
C +VSSQKQ A KAT+D++ SVSNIATEIK+G SGTVSSQK+PA KATSDEKDS SNI
Sbjct: 5 CFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 64
Query: 216 REKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDE 275
E K+G+ S TVS QK A K K+ S+LNIA G KS TVS ++ P KAT D+
Sbjct: 65 TEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDK 124
Query: 276 KDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQP 335
DS LNIA KDG + VSS KQP+LKAT+D+EDSV N+ATE KD + SGTVS QKQP
Sbjct: 125 TDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 184
Query: 336 ALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRG 395
ALKAT+D++DSV NI TEIKDG++S TVSSQKQPA KAT+ ++DSVS IATEIKDG+ G
Sbjct: 185 ALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSG 244
Query: 396 TVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATR 455
TVSS+++PALK T DEKDS SNI RE KDGE S TV+ +K + K ++ S+LNIA
Sbjct: 245 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARG 304
Query: 456 ITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTS 496
G K+ LKAT + KDS N + K+ +TS
Sbjct: 305 KEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETS 345
Score = 311 bits (797), Expect = 2e-84
Identities = 174/251 (69%), Positives = 200/251 (79%)
Query: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
+S QKQ A KAT+D++DSVSNIATEIK+G SGTVSSQKQPA KAT+DE+DSV NIATEI
Sbjct: 144 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEI 203
Query: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
K+G++S TVS QKQ A K ++ S+ IAT I G KSGTVSS+K+PA K SD+ DS
Sbjct: 204 KDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDS 263
Query: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202
N E KDG TV+S+K LKAT+DEE SV NIA +DGEK+ VSS+KKPALK
Sbjct: 264 FSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALK 323
Query: 203 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 262
ATSDEKDSFSNITREKKDGE SRTVSSQKPPALKATS +EDSVL+IARE+KDGEKSRTVS
Sbjct: 324 ATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVS 383
Query: 263 FEQPPGLKATR 273
EQPPGLK +
Sbjct: 384 SEQPPGLKVMK 394
Score = 307 bits (786), Expect = 4e-83
Identities = 194/371 (52%), Positives = 237/371 (63%), Gaps = 13/371 (3%)
Query: 192 TVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIARE 251
+VSSQK+PA KATSD+KDS SNI E K+G IS TVSSQK PA KATS ++DSV NIA E
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 252 KKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKED 311
K+G++S TVS ++ K +K SLLNIA G K+ VSS KQP+ KATSDK D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 312 SVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAW 371
S N+ATE KD GTVS QKQPALKAT+D++DSVSNI TEIKDG++SGTVSSQKQPA
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 372 KATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTV 431
KAT+ ++DSV NIATEIKDG+ TVSSQ++PALK T DE+DSVS IA EIKDGEKSGTV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 432 SPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTA---- 487
S +K+ A K +K S NI G S T E LKAT + +DSVLN A
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 488 ---------TKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDII 538
++ K +T E+D E+K E Q + + D +D +
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 539 QSSQTVSEDGD 549
S +DG+
Sbjct: 367 LSIAREEKDGE 377
Score = 237 bits (605), Expect = 4e-62
Identities = 147/292 (50%), Positives = 185/292 (63%)
Query: 260 TVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATE 319
+VS ++ P KAT D+KDS+ NIA K+G + VSS KQP+ KATSD++DSV N+ATE
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 320 TKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 379
K+ Q SGTVS QKQ A K KK S+ NI T I G +SGTVSSQKQPA KATS K D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 380 SVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 439
S NIATEIKDG GTVSSQ++PALK T DE+DSVSNIA EIKDGEKSGTVS QKQ A
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 440 KVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPA 499
K ++ S+LNIAT I G KS T + LKAT + +DSV AT++K+ + S
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 500 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 551
+ A + + + N + K+ SR + + S++ DS+
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSV 298
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 531 bits (1369), Expect = e-150
Identities = 323/692 (46%), Positives = 434/692 (62%), Gaps = 37/692 (5%)
Query: 380 SVSNIATEIKDGQIRGTVS----SQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQK 435
+ + A K IRG +S ++R +L+ + E+D E + E + PQ
Sbjct: 239 TAEDYAVASKFQAIRGMISEYKANKRCKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298
Query: 436 QSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQT 495
+ K KK+ + Y +++ L I+N+ K
Sbjct: 299 EEKMKKCRNKKMEVSRNVH-----ADDSDNYNDDVDELIHKIKNR----------KPDNH 343
Query: 496 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 554
+P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + +
Sbjct: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397
Query: 555 CKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQ 614
+N +LLI+Q M+CKD V L K KN R I+ + +CE+L+VK +K+KN SVLQ
Sbjct: 398 DENFMLLIEQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457
Query: 615 KRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 674
K +SE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR
Sbjct: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517
Query: 675 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 733
+ +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT
Sbjct: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577
Query: 734 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRS 791
IK+QN E KY KD EI+K +EDL+K LKRN E L KTI YS +L L DENT L S
Sbjct: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEEALTKTITRYSKELNVLMDENTMLNS 637
Query: 792 KLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNS 851
+L+K+++S RLETEM+SYRCRL AA CDHDQ SSKRD +LAFQ TV++ HLQE+ NS
Sbjct: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697
Query: 852 HVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 911
H+ ILS QLSKAES S L+TELHY EALKEK L EH+Q L + Q +++DIE MY++
Sbjct: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757
Query: 912 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQN 967
+EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ V+
Sbjct: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817
Query: 968 LQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSA 1027
LQAECRK LEE+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK
Sbjct: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873
Query: 1028 TKALLDASSRHCTYLENGMQDSRKKLDQMRSQ 1059
+A+L+ SS LE+ Q +KKL QMRSQ
Sbjct: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 374 bits (959), Expect = e-103
Identities = 280/856 (32%), Positives = 436/856 (50%), Gaps = 118/856 (13%)
Query: 337 LKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGT 396
L +D K + +I + K+ + + P +K+D ++ Q +
Sbjct: 401 LDCDNDNKPGIGHIFSTDKNFHNDASTKKARNPEVVMVEMKEDQEFDLQMTKNMNQNSDS 460
Query: 397 VSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVI-FKKKVSLL----- 450
S+ +LK + N++ D +++ V ++ Q + FK +V+ L
Sbjct: 461 GSTNNYKSLKP------KLENLSSLPPDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFL 514
Query: 451 -----------NIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPA 499
++ + + TE L T T+ N D LN KE
Sbjct: 515 ALKKEDVQLHKDVEEEMEKHRSNSTELSGTL-TDGTTVGNDDDGLNQQIPRKE------- 566
Query: 500 EQDLEMASEGEQKR-LEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNV 558
GE R ++ N + +VKNQI+ D D ++ S+ SED + +N
Sbjct: 567 --------NGEHDRPADKTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYENF 618
Query: 559 ILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRIS 618
+LLI+Q M+ KD L +I++TFCL + L+KLK+NHC+QL VK+++++N SVLQ +S
Sbjct: 619 MLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELS 678
Query: 619 EKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEAD 678
E ++ K QL+ + +E EKEL LR A++QE +++RN + L+ K E+LRI EE+ +
Sbjct: 679 ETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVE 738
Query: 679 VTKPIKPALKSAEVELKTGGNN-------------------------------------- 700
+ +K L+ EL+T NN
Sbjct: 739 TKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEM 798
Query: 701 -----SNQVSETDEKE-DLLHENRLMQDEIARLRLEKDTIKNQN--LEKKYLKDFEIVKR 752
++++S +KE DL HE+ ++Q+EIA LRLE DTIKNQN EKKY +D E VK
Sbjct: 799 ARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKE 858
Query: 753 KHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRC 812
K+++LQK +K N ETL +TI YSGQL LT EN L S+LE +++++RLE EM+SYRC
Sbjct: 859 KNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRC 918
Query: 813 RLNAARCDHDQSHSSKRDQELAFQGT-------VDKCRHLQENLNSHVLILSLQLSKAES 865
RL AA D DQS ++ RD +L FQ T DK + L + ILS +LS AES
Sbjct: 919 RLAAAVRDCDQSQTA-RDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAES 977
Query: 866 KSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ-- 923
K L+ +LH T +AL ++L+ E VQ +L Q Q Q K+ E+MY+ + ++K I KQ
Sbjct: 978 KINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQES 1037
Query: 924 --ERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEE 981
ER QL+ +NMLL+QQLDDA KA++QEK IQ + + +NLQAE K L L+E
Sbjct: 1038 VEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQE 1097
Query: 982 DNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQ----------KRDDVLNKGSATKAL 1031
NK L++E NH KE+ Q EKEKA R++ + + Q+ ++VL T
Sbjct: 1098 KNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQL-QQTLFS 1156
Query: 1032 LDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMM 1091
+ A + C L+ + ++++ ++S + + + + KL +E
Sbjct: 1157 MKAIQKQCETLQKNKKQLKQEVVNLKSYMER---------NMLERGKAEWHKLLIEERAR 1207
Query: 1092 RKIIKKQDDQIERLEK 1107
++I +K ++ I L+K
Sbjct: 1208 KEIEEKLNEAILTLQK 1223
Score = 63.5 bits (153), Expect = 1e-09
Identities = 108/537 (20%), Positives = 223/537 (41%), Gaps = 92/537 (17%)
Query: 615 KRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVE-ELHQKVREKLRITEEQY 673
K +EK E+K+Q+ E FA E + + + EL V E + EQ
Sbjct: 576 KTSNEKNEVKNQIYPEA----------DFADSMEPSEIASEDCELSHSVYENFMLLIEQL 625
Query: 674 RIEADVTKP---IKPALKSAEVELKTGGNNSNQVS-ETDEKEDLLH--ENRLMQDEIARL 727
R+E + I+ E LK N+ +Q++ + + E+++ +N L + + +L
Sbjct: 626 RMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKL 685
Query: 728 RLEKDTI-------------KNQNLEKK-----YLKDFEIVKRKHEDLQKA------LKR 763
+LE I K +N EK+ Y KD E ++ K E+ K LK
Sbjct: 686 QLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKW 745
Query: 764 NGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAAR--CDH 821
N L K + L + E + +L +++++R + + S + L AR +
Sbjct: 746 NLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNS 805
Query: 822 DQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEAL 881
+ SH +++++L + + L + +L L++ +++++ + + EA+
Sbjct: 806 EISHRHQKEKDLFHEDCM---------LQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAV 856
Query: 882 KEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLD 941
KEK +++Q +K + + + Y N L +N +L +L+
Sbjct: 857 KEKN---DNLQKIIKLNEETLTETILQYSGQLNN-------------LTAENKILNSELE 900
Query: 942 DARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQ-Y 1000
+ + NQE+ + +++ CR + + D +L ++ Q +
Sbjct: 901 NGKQ---NQERLEIEMESY----------RCRLAAAVRDCDQSQTARDLKLDFQRTRQEW 947
Query: 1001 EKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQF 1060
+ + +V + LQ K + + K S ++ +++ L+ + ++R L +
Sbjct: 948 VRLHDKMKVDMSGLQAKNEILSEKLSNAESKINS-------LQIQLHNTRDALGRESLIL 1000
Query: 1061 QEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQ 1117
+ +Q L+ T KE E Q ++E ++K I KQ+ ERL ++ + L+ Q
Sbjct: 1001 ERVQRDLSQTQCQKKETE---QMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQ 1054
Score = 52.8 bits (125), Expect = 2e-06
Identities = 155/834 (18%), Positives = 299/834 (35%), Gaps = 139/834 (16%)
Query: 377 KKDSVSNIATEIKDGQIRGTVSSQRRPALKTTG-DEKDSVSNIAREIKDGEKSGTVSPQK 435
+K S+ + E K+ Q ++ P T D ++ +K +K +VSP
Sbjct: 112 RKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVDDKCPSVSPSM 171
Query: 436 QSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTA-TKMKEVQ 494
Q K++ +N+ R E + T + D++ + +++ E +
Sbjct: 172 PENQSAT--KELGQMNLTER------------EKMDTGVVLLSGNDTLHDLCQSQLPENK 217
Query: 495 TSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQ---IHSRDDLDDI--------IQSSQT 543
S AEQD E+ SE EQ+RL+ EN QPQ +Q + D +DI +Q S+
Sbjct: 218 ESKEAEQDSELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEE 277
Query: 544 VSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKI 603
+ + L KN + L+ +E+K + K K C + L DN VK
Sbjct: 278 MWIEQGKL--EWKNQLKLV-INELKQRFGEIYEKYKIPACPEEE--PLLDNSTRGTDVKD 332
Query: 604 RKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVR 663
++ + EI + E +KE SL+ I +E +
Sbjct: 333 IPFNLTNNIPGCEEEDASEISVSVVFETFPEQKE-PSLKNIIHPYYHPYSGSQEHVCQSS 391
Query: 664 EKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDE 723
K + E + D KP + T N N S + + + +D+
Sbjct: 392 SKFHLHEN----KLDCDNDNKPGIGHI---FSTDKNFHNDASTKKARNPEVVMVEMKEDQ 444
Query: 724 IARLRLEKDTIKNQNLEKKYLKDFEIVKRKHED---------------LQKALKRNGETL 768
L++ K+ NQN + +++ +K K E+ L + L+++ +
Sbjct: 445 EFDLQMTKN--MNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQDMQKF 502
Query: 769 AKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHD-QSHSS 827
+ + AL E+ L +E++ E + TE+ D D +
Sbjct: 503 KNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGLNQQI 562
Query: 828 KRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALV 887
R + DK + ++N + + + + S + + + + L+
Sbjct: 563 PRKENGEHDRPADKTSN-EKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLL 621
Query: 888 FEHVQSELKQKQS---------------------------QMKDIEKMYKSGYNTMEKCI 920
E ++ E K S ++K +E M N +
Sbjct: 622 IEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELS--- 678
Query: 921 EKQERFCQLKKQNMLLQQQLDDAR--NKADNQEKAILNIQARCDA-RVQNLQAECRK--- 974
E ++ QL+ Q + +++L D R K +N+EK ++ D+ +++ + EC K
Sbjct: 679 ETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVE 738
Query: 975 ----------------------------------HRLLLEEDNKMLVNELNHSKEKECQY 1000
+L E+D ++L +++ SK+KE +
Sbjct: 739 TKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEM 798
Query: 1001 EKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQF 1060
++K E++ R QK D+ ++ + + ++N + KK +
Sbjct: 799 ARKKMNSEISHR--HQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAV 856
Query: 1061 QEIQDQLTATIRCTKE--------MEGDTQKLEVEHVMMRKIIKKQDDQIERLE 1106
+E D L I+ +E G L E+ ++ ++ ERLE
Sbjct: 857 KEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLE 910
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 369 bits (946), Expect = e-101
Identities = 329/1054 (31%), Positives = 511/1054 (48%), Gaps = 122/1054 (11%)
Query: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
+SP K+ +EK T K IA E KE P+ T + + K EK IA
Sbjct: 340 MSPAKETSEKFTWAAKGRPRKIAWEKKETPVK-TGCVARVTSNKTKVLEKGRSKMIACPT 398
Query: 83 KEGQQSGTVSPQKQSAQ-------------KVIFKKKVSLL-----NIATRIMGGGKSGT 124
KE + + Q+ ++ + +F+ + +I ++M +
Sbjct: 399 KESSTKASANDQRFPSESKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVE 458
Query: 125 VSSQKQPASKTASDKTDSALNTATEIKD--GLQCGTV----SSQK--------QQALKAT 170
+K A K A + +S N A E+K+ L+ + S QK ++L T
Sbjct: 459 EPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLRADPMFPPESKQKDYEENSWDSESLCET 518
Query: 171 TDEEGSVSNIATEIKDGEK-SGTV--SSQKKPALKATSDEKDSFSNITREKKDGEISRTV 227
++ AT K+ +K +G + S K LKAT K S E KD + +
Sbjct: 519 VSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAE 578
Query: 228 SSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKK 287
KP A + + + SV N A E K+ + R D +L +K
Sbjct: 579 PPGKPSAFEPATEMQKSVPNKALELKNEQTLRA----------------DEILPSESKQK 622
Query: 288 DGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTV--SCQKQPALKATSDKKD 345
D E+ S + + S K+ +P A + + ++I+G + S K LKA K
Sbjct: 623 DYEEN---SWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKV 679
Query: 346 SVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQ------IRGTVSS 399
S+ E+ D Q +K A++ + SV N A E+K+ Q I + S
Sbjct: 680 SIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESK 739
Query: 400 QR--------RPALKTTGDEKDSVSNIAREIKDGEK-SGTV--SPQKQSAQKVIFKKKVS 448
Q+ +L T +KD A K+ +K +G + SP K + KVS
Sbjct: 740 QKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVS 799
Query: 449 LLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASE 508
+ A + E PE + IE + SV N A ++K QT D SE
Sbjct: 800 IPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQT---LRADQMFPSE 856
Query: 509 GEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMK 568
+QK++EE + ++ + +D +C +D+ K
Sbjct: 857 SKQKKVEENSWDSESLRETVSQKD------------------VCVPKATHQKEMDKISGK 898
Query: 569 CKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLK 628
+D L KI +T +R +L+ +HCEQ K+ ++K K VL+K++SE +EIKSQL+
Sbjct: 899 LEDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLE 958
Query: 629 HEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALK 688
++ ++ E+ELCS+R + QE++KRRN + L++K+RE+L EEQ+R E +V + ++ AL+
Sbjct: 959 NQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALR 1018
Query: 689 SAEVELKTGGNNSNQVSETDEKED-LLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLK 745
++ELK+ +N NQVS T E E+ LLHEN +++ EIA L+LE T+K+Q EK KY +
Sbjct: 1019 IQDIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFE 1078
Query: 746 DFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLET 805
D +I+K K+ +LQ LK E+L K + YSGQL L ENT L SKL K+++ ++ LE
Sbjct: 1079 DIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEA 1137
Query: 806 EMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------ILSL 858
E++S+ RL +A DHDQ +S++ QE AF D C LQ +N V +L
Sbjct: 1138 EIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDAC--LQRKMNVDVSSTIYNNEVLHQ 1195
Query: 859 QLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEK 918
LS+A+ KS+ LK L+Y G+AL+E LV EH Q + ++ Q QMK+ E MY++ + + K
Sbjct: 1196 PLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNK 1255
Query: 919 CIEKQE----RFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRK 974
E+QE + QL+ +NM LQQQL A KADN+ K ++I L+ + +
Sbjct: 1256 HTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHF--------LERKMQH 1307
Query: 975 HRLLLEEDNKMLVNELNHSKEKECQYEKEKAERE 1008
H LL+E N+ + N NH K + QYEKEKAE E
Sbjct: 1308 H--LLKEKNEEIFNYNNHLKNRIYQYEKEKAETE 1339
Score = 79.3 bits (194), Expect = 2e-14
Identities = 245/1160 (21%), Positives = 429/1160 (36%), Gaps = 198/1160 (17%)
Query: 24 SPQKQRAEKATSDD-KDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
S + Q EKATS + S EI S K+ +EK T K IA E
Sbjct: 280 SDKIQCLEKATSGKFEQSAEETPREI--------TSPAKETSEKFTWPAKGRPRKIAWEK 331
Query: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
KE +SP K++++K + K G+ ++ +K+
Sbjct: 332 KEDTPREIMSPAKETSEKFTWAAK-------------GRPRKIAWEKKE----------- 367
Query: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202
T +K G V+S K + L E+G IA K+ + + Q+ P+ +
Sbjct: 368 -----TPVKTGC-VARVTSNKTKVL-----EKGRSKMIACPTKESSTKASANDQRFPS-E 415
Query: 203 ATSDEKDSFSNITRE-----------------KKDGEISRTVSS--QKPPALKATSVKED 243
+ +E + +S +R +K EI+R V +KP A K ++
Sbjct: 416 SKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQN 475
Query: 244 SVLNIAREKKDGE----------KSRTVSFEQ----PPGLKATRDEKDSLLNIARGKKDG 289
SV N A E K+ + +S+ +E+ L T +KD L A +K+
Sbjct: 476 SVPNKAFELKNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEI 535
Query: 290 EKTR---RVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDS 346
+K S +K LKAT + S+P A E KD Q K A + ++ + S
Sbjct: 536 DKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKS 595
Query: 347 VSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALK 406
V N E+K+ Q +++ D + ++ KD + +S +L
Sbjct: 596 VPNKALELKNEQ----------------TLRADEILPSESKQKDYE----ENSWDTESLC 635
Query: 407 TTGDEKDSVSNIAREIKDGEK-SGTV--SPQKQSAQKVIFKKKVSLLNIATRITGGGKSG 463
T +KD A K+ +K +G + SP K K KVS+ A +
Sbjct: 636 ETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFK 695
Query: 464 TEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQ 523
E PE + IE + SV N A ++K QT D + SE +QK EE +
Sbjct: 696 AEPPEKPSAFEPAIEMQKSVPNKALELKNEQT---LRADEILPSESKQKDYEESSWDSES 752
Query: 524 VKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFC 583
+ + +D +C ID+ K ++ C
Sbjct: 753 LCETVSQKD------------------VCLPKATHQKEIDKINGKLEESPDNDGFLKAPC 794
Query: 584 LWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRF 643
K I K ++ + K S + I E++ + ++ LEL+ E
Sbjct: 795 RMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI----EMQKSVPNKALELKNEQTLRAD 850
Query: 644 AIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ 703
+ + K++ VEE + E LR T Q DV P K + K G +
Sbjct: 851 QMFPSESKQKKVEE-NSWDSESLRETVSQ----KDVCVPKATHQKEMD---KISGKLEDS 902
Query: 704 VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKR 763
S + D +H + E+ + E+ T K + ++KK+ ++K+K + K +K
Sbjct: 903 TS-LSKILDTVHSCERAR-ELQKDHCEQRTGKMEQMKKKFC----VLKKKLSEA-KEIKS 955
Query: 764 NGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQ 823
E Q E ++R L ++ E R+ + + R L H +
Sbjct: 956 QLEN----------QKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRK 1005
Query: 824 SHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKE 883
K+ E A + + + ++ NLN Q+S L LH KE
Sbjct: 1006 ELEVKQQLEQALRIQDIELKSVESNLN--------QVSHTHENENYL---LHENCMLKKE 1054
Query: 884 KALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDA 943
A++ + E+ + Q ++ E Y +++ + + +LK++++ +
Sbjct: 1055 IAML----KLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSG 1110
Query: 944 RNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLE---EDNKMLVNELN------HSK 994
+ K E +L + + + L+AE H L +D+ +V H
Sbjct: 1111 QLKVLIAENTMLTSKLKEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIA 1170
Query: 995 EKECQYEKEKAEREVAVRQ---LQQKRDDVLNKGSATKALL----DASSRHCTYLENGMQ 1047
C K + + L Q + K + K L DA + E+ +
Sbjct: 1171 GDACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQR 1230
Query: 1048 DSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQK---LEVEHVMMRKII----KKQDD 1100
D R+ QM+ Q++ + T++ E QK L+ +++ +++ + KK D+
Sbjct: 1231 DQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADN 1290
Query: 1101 Q------IERLEKILQHSSL 1114
+ I LE+ +QH L
Sbjct: 1291 KSKITIDIHFLERKMQHHLL 1310
Score = 42.7 bits (99), Expect = 0.002
Identities = 154/834 (18%), Positives = 311/834 (37%), Gaps = 89/834 (10%)
Query: 264 EQPPGLKATRDEKDSLL----NIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATE 319
E P ++ T D +SL+ + A +G + K S K E++ + +
Sbjct: 249 EAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPREITSP 308
Query: 320 TKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQP---AW--KAT 374
K+ T + +P A K+D+ I + K+ + T +++ +P AW K T
Sbjct: 309 AKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKET 368
Query: 375 SVKKDSVSNIATE----IKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGT 430
VK V+ + + ++ G+ + + + K + +++ S +E +D E S
Sbjct: 369 PVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQE-EDEEYSCD 427
Query: 431 VSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKM 490
+S+ K+ S+ I + E P+ K IE ++SV N A ++
Sbjct: 428 SRSLFESSAKIQVCIPESIYQKVMEIN---REVEEPPKKPSAFKPAIEMQNSVPNKAFEL 484
Query: 491 KEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDS 550
K QT D E +QK +YE N ++ + D + + E
Sbjct: 485 KNEQT---LRADPMFPPESKQK---DYEENSWDSESLCETVSQKDVCLPKATHQKE---- 534
Query: 551 LCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKA 610
ID+ K ++ + + C K I K + ++ + K
Sbjct: 535 -----------IDKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKP 583
Query: 611 SVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITE 670
S + E++ + ++ LEL+ E I + K+++ EE + E L T
Sbjct: 584 SAFEPAT----EMQKSVPNKALELKNEQTLRADEILPSESKQKDYEE-NSWDTESLCETV 638
Query: 671 EQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLE 730
Q DV P A E++ G + V K+ LL N M+ I LE
Sbjct: 639 SQ----KDVCLP--KAAHQKEIDKINGKLEGSPV-----KDGLLKANCGMKVSIPTKALE 687
Query: 731 ---KDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENT 787
T K + EK + I +K + +N +TL + + +
Sbjct: 688 LMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTL---------RADEILPSES 738
Query: 788 TLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQE 847
+ E +S ET Q C A + K ++ G + ++
Sbjct: 739 KQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKV 798
Query: 848 NLNSHVL-ILSLQLSKAESKSRVLKTELHYTGE-ALKEKALVFEHVQS----ELKQKQSQ 901
++ + L ++ +Q KAE + E + ++ KAL ++ Q+ ++ +S+
Sbjct: 799 SIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFPSESK 858
Query: 902 MKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARC 961
K +E+ + E +K C K + Q+++D K ++
Sbjct: 859 QKKVEENSWDSESLRETVSQKD--VCVPKATH---QKEMDKISGKLEDSTSL-------- 905
Query: 962 DARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKR--- 1018
+++ + C + R L ++ + ++ K+K C +K+ +E + QL+ ++
Sbjct: 906 -SKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKW 964
Query: 1019 DDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIR 1072
+ L T + R+ L +++ ++++ + E++ QL +R
Sbjct: 965 EQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALR 1018
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 322 bits (825), Expect = 1e-87
Identities = 289/894 (32%), Positives = 446/894 (49%), Gaps = 84/894 (9%)
Query: 162 QKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDG 221
+K A K + + +V N A E+K+ E++ + K DE++S+ D
Sbjct: 527 EKPSAFKPAVEMQKTVPNKAFELKN-EQTLRAAQMFPSESKQKDDEENSW--------DS 577
Query: 222 EISRTVSSQKPPAL-KATSVKEDSVLNIAREK---KDGEKSRTVSFEQPPGLKATRDEKD 277
E SQK L KAT KE L+ E+ KDG LK T K
Sbjct: 578 ESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGL------------LKPTCGRKV 625
Query: 278 SLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPAL 337
SL N A KD E + S K LK T ++ S+PN A E KD + S L
Sbjct: 626 SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLL 685
Query: 338 KATSDKKDSVSNIPTEIKD------GQQSGTVSSQK---QPAWKATSVKKDSVSNI---- 384
K T +K S+ N E+KD Q + S QK + +W S + + N
Sbjct: 686 KPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEENSWDFESFLETLLQNDVCLP 745
Query: 385 -ATEIKD-GQIRGTV--SSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 440
AT K+ + G + S + LK T K S+ N A E+KD E +
Sbjct: 746 KATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDVSSVESTF 805
Query: 441 VIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPA- 499
+F K + + +T++ T+ +T+ E ++ A + + + T
Sbjct: 806 SLFGKPTTENSQSTKVEEDFNLTTKEGAT-KTVTGQQERDIGIIERAPQDQTNKMPTSEL 864
Query: 500 --EQDLEMASEGEQKRLEEYENNQ--PQVKNQIHSRDDLDDIIQSSQTVS--EDGDSLCC 553
++D + S+ E + + +N + P+ Q + I +S + S E +
Sbjct: 865 GRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQN 924
Query: 554 NCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVL 613
+ N L + D L KI + +R +LK ++CEQ+ K+ + KNK VL
Sbjct: 925 SVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVL 984
Query: 614 QKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQY 673
QK +SE +EIKSQL+++ + E+ELCS+R + QE++KRRNV+ L +K+R EEQ
Sbjct: 985 QKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIR-----PEEQL 1039
Query: 674 RIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKD 732
R + +V + ++ L+ ++ELK+ +N NQVS T E E DL HEN +++ EIA L+LE
Sbjct: 1040 RKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLKKEIAMLKLEVA 1099
Query: 733 TIKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLR 790
T+K+Q+ E KY +D +I++ K+ +LQ LK +T+ K + Y QL LT ENT L
Sbjct: 1100 TLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLT 1159
Query: 791 SKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLN 850
SKL K+++ ++ LETE++S+ RL +A DHDQS +S+++QELAF D LQ +N
Sbjct: 1160 SKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGD--APLQGIMN 1216
Query: 851 SHVL-------ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMK 903
V +L L +A+ KS+ K L+Y G+ L+E ALV EH Q + + Q QMK
Sbjct: 1217 VDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQRDRCETQCQMK 1276
Query: 904 DIEKMYKSGYNTMEKCIEKQE----RFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQA 959
E MY++ + ++K E+QE + QL+ +N L+QQL A K N+ K +NIQ
Sbjct: 1277 KAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKV-NKSKVTINIQF 1335
Query: 960 RCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQ 1013
+ + ++H L E N+ + N NH KE+ QYEKEKAEREV++++
Sbjct: 1336 P--------EMKMQRH---LNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKK 1378
Score = 65.5 bits (158), Expect = 3e-10
Identities = 187/900 (20%), Positives = 345/900 (38%), Gaps = 147/900 (16%)
Query: 20 RIELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 79
++E SP K K T K S+ N A E+K+ S K K T K S+ N A
Sbjct: 606 KLEESPVKDGLLKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKA 665
Query: 80 TEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDK 139
E+K+ + SP K +KVSL N A + + ++Q P+ D
Sbjct: 666 LELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELK--DRETFKAAQMFPSESKQKDD 723
Query: 140 TDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKP 199
+++ + + ++ LQ KAT +E ++ ++++ S K
Sbjct: 724 EENSWDFESFLETLLQNDVCLP------KATHQKE--FDTLSGKLEE-------SPDKDG 768
Query: 200 ALKATSDEKDSFSNITREKKDGEI--SRTVSS--------QKPPALKATSVKEDSVLNIA 249
LK T K S N E KD E + VSS KP + S K + N+
Sbjct: 769 LLKPTCGMKISLPNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLT 828
Query: 250 REKKDGEKSRTVSFEQPPGL--KATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATS 307
K+ K+ T E+ G+ +A +D+ + + G+K+ K+TS
Sbjct: 829 -TKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKE-------------DTKSTS 874
Query: 308 DKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQK 367
D E ++T++ + + QK+ +K T+ K + P+ + + K
Sbjct: 875 DSEII---SVSDTQNYECLPEATYQKE--IKTTNGKIEESPEKPSHFEPATEMQNSVPNK 929
Query: 368 QPAWK-ATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGE 426
WK +++ DS + ++I D S +R LK KD+ I +++ +
Sbjct: 930 GLEWKNKQTLRADSTT--LSKILD----ALPSCERGRELK-----KDNCEQITAKMEQTK 978
Query: 427 KSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNT 486
V ++ S K I K L N ++ + L +++ T+ ++
Sbjct: 979 NKFCVLQKELSEAKEI---KSQLEN----------QKAKWEQELCSVRLTLNQEEEKRRN 1025
Query: 487 ATKMKE-------VQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQ 539
+KE ++ +Q LE + L+ +N QV H+ + +D+
Sbjct: 1026 VDILKEKIRPEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVS---HTHESENDLFH 1082
Query: 540 SSQTVSEDGDSLCCNCKNVILLIDQHEMKCK---DCVHLLKIKNTFCLWKRLIKLK--DN 594
+ + ++ + V L QH++K + + +L+ KN +K K
Sbjct: 1083 ENCMLKKE---IAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTK 1139
Query: 595 HCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRN 654
Q R +++ L + ++L ++ EK++ K L+ EI L S Q R+N
Sbjct: 1140 RASQYREQLKVLTAENTMLTSKLKEKQD-KEILETEIESHHPRLASALQDHDQSVTSRKN 1198
Query: 655 VEELHQKVREKLRITEEQYRIEADVTKPI------KPALKSAEVELKTGGNNSNQVSETD 708
E + Q + DV+ I L A+ + K+ N N
Sbjct: 1199 QELAFHSAGD----APLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAG--- 1251
Query: 709 EKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETL 768
D L EN L+ + R R E + + E Y + + V KH + Q++L++
Sbjct: 1252 ---DDLRENALVSEHAQRDRCETQ-CQMKKAEHMYQNEQDNVD-KHTEQQESLEQ----- 1301
Query: 769 AKTIACYSGQLAALTDENTTLRSKL--EKQRESRQRLETEMQSYRCRLNAARCDHDQSHS 826
+L L +N LR +L ++ ++ ++ +Q ++ Q H
Sbjct: 1302 ---------KLFQLESKNRWLRQQLVYAHKKVNKSKVTINIQFPEMKM--------QRHL 1344
Query: 827 SKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKAL 886
+++++E+ G HL+E ++ Q K +++ V + Y LKE L
Sbjct: 1345 NEKNEEVFNYG-----NHLKERID--------QYEKEKAEREVSIKKYKYFSNFLKESGL 1391
Score = 32.0 bits (71), Expect = 3.4
Identities = 28/170 (16%), Positives = 74/170 (43%), Gaps = 17/170 (10%)
Query: 950 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1009
+ K L + +++ + C + R L +++ + + ++ +K K C +KE +E +
Sbjct: 934 KNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKE 993
Query: 1010 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1069
QL+ ++ + + + L N ++ R+ +D ++ + + ++QL
Sbjct: 994 IKSQLENQKAKWEQELCSVRLTL-----------NQEEEKRRNVDILKEKIRP-EEQLRK 1041
Query: 1070 TIRCTKEMEGDTQKLEVEHVMMRKIIK--KQDDQIERLEKILQHSSLMLQ 1117
+ +++E Q L ++ + ++ + Q E L H + ML+
Sbjct: 1042 KLEVKQQLE---QTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLK 1088
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 249 bits (637), Expect = 8e-66
Identities = 188/574 (32%), Positives = 292/574 (50%), Gaps = 95/574 (16%)
Query: 455 RITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRL 514
RI G G P +LK + E +D + A + K VQT AEQ L +ASE EQ+R
Sbjct: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
Query: 515 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 574
E E QPQV I+ + T +
Sbjct: 376 ERSEKKQPQV-------------IEGNNTYKSEK-------------------------- 396
Query: 575 LLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI--- 631
I+L +N C + S R++++ +I +
Sbjct: 397 --------------IQLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
Query: 632 LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 691
L+ E + C+L+ QE +++ NV LH+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
Query: 692 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 748
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
Query: 749 IVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 808
I K + L+K +K N E + KT Y +L L ENT L S+L K++ES+++LE E++
Sbjct: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
Query: 809 SYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKA 863
SY+ RL AA H ++ ++R+ +LA + T D ++ + L+ QLSK
Sbjct: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
Query: 864 ESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 922
+ K LK + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
Query: 923 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLL 979
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
Query: 980 EEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQ 1013
EE NK L+NE +H KE QYE++KAE V++++
Sbjct: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 249 bits (637), Expect = 8e-66
Identities = 188/574 (32%), Positives = 292/574 (50%), Gaps = 95/574 (16%)
Query: 455 RITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRL 514
RI G G P +LK + E +D + A + K VQT AEQ L +ASE EQ+R
Sbjct: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
Query: 515 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 574
E E QPQV I+ + T +
Sbjct: 376 ERSEKKQPQV-------------IEGNNTYKSEK-------------------------- 396
Query: 575 LLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI--- 631
I+L +N C + S R++++ +I +
Sbjct: 397 --------------IQLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
Query: 632 LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 691
L+ E + C+L+ QE +++ NV LH+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
Query: 692 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 748
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
Query: 749 IVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 808
I K + L+K +K N E + KT Y +L L ENT L S+L K++ES+++LE E++
Sbjct: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
Query: 809 SYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKA 863
SY+ RL AA H ++ ++R+ +LA + T D ++ + L+ QLSK
Sbjct: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
Query: 864 ESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 922
+ K LK + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
Query: 923 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLL 979
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
Query: 980 EEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQ 1013
EE NK L+NE +H KE QYE++KAE V++++
Sbjct: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
>gi|169217530 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 121
Score = 224 bits (571), Expect = 4e-58
Identities = 114/116 (98%), Positives = 116/116 (100%)
Query: 1006 EREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQD 1065
E++VAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQD
Sbjct: 6 EKKVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQD 65
Query: 1066 QLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES 1121
QLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES
Sbjct: 66 QLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES 121
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sapiens]
Length = 823
Score = 217 bits (552), Expect = 6e-56
Identities = 145/435 (33%), Positives = 246/435 (56%), Gaps = 29/435 (6%)
Query: 594 NHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI---LELEKELCSLRFAIQQEKK 650
N E++++ + +S R++++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 651 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ-VSETDE 709
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N+ +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEE 506
Query: 710 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNGET 767
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K N E
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 768 LAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSS 827
+ +T Y +L L ENT L ++L K++ES++RLE +++SY+ RL AA H +S +
Sbjct: 567 ITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 828 KRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALK 882
+R+ +LA + T D ++ + L+ QLS+ + K LK + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 883 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 938
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 939 QLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKEC 998
QLDD K D++E + NIQ E K L+LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 999 QYEKEKAEREVAVRQ 1013
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
Score = 45.8 bits (107), Expect = 2e-04
Identities = 118/622 (18%), Positives = 234/622 (37%), Gaps = 128/622 (20%)
Query: 242 EDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQP 301
+D LN+A ++ EK E PG + + I G+ +G K P
Sbjct: 289 DDKDLNVATKQCVPEKVS----EPLPGSSHEKGNR-----IVNGQGEGPPA------KHP 333
Query: 302 SLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSG 361
SLK + TE +D + G V + L+A +P ++ Q+
Sbjct: 334 SLKPS-----------TEVEDPAVKGAVQRKNVQTLRAE-------QALPVASEEEQERH 375
Query: 362 TVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIARE 421
S +KQP ++K+G T S++ + D S + A
Sbjct: 376 ERSEKKQP-----------------QVKEG--NNTNKSEKIQLSENICDSTSSAA--AGR 414
Query: 422 IKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKD 481
+ K G PQ+ F KK+ + + + T + + +E K+
Sbjct: 415 LTQQRKIGKTYPQQ-------FPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKE 467
Query: 482 SVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSS 541
+ K+++ P Q LEM S+ + N P H+ +++ ++ +
Sbjct: 468 KQYKKEVEAKQLE---PTVQSLEMKSKTAR--------NTP--NRDFHNHEEMKGLMDEN 514
Query: 542 QTVSEDGDSL---CCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQ 598
+ D L C KN D E + K + +K T ++ IKL + +
Sbjct: 515 CILKADIAILRQEICTMKN-----DNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE 569
Query: 599 LRVKIRK----LKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRN 654
+ ++ LK + + L + +++E K +L+ +I + L + + K RN
Sbjct: 570 TAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERN 629
Query: 655 VEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLL 714
++ ++ R+ ++ +++ I E + Q+SET K + L
Sbjct: 630 LKLALERTRD--------VSVQVEMSSAISKVKDENEF-------LTEQLSETQIKFNAL 674
Query: 715 HEN-RLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIA 773
+ R +D + + L +T++N D +++ +++ K + +N E
Sbjct: 675 KDKFRKTRDSLRKKSLALETVQN---------DLSQTQQQTQEM-KEMYQNAEAKVNNST 724
Query: 774 ----CYSGQLAALTDENTTLRSKLE--KQRESRQRLETEMQSYRCRLNAARCDHDQSHSS 827
C ++ L EN L +L+ Q+E + + T +Q R + + + D S
Sbjct: 725 GKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQ--RGFIESGKKDLVLEEKS 782
Query: 828 KRDQELAFQGTVDKCRHLQENL 849
K+ +++C HL+E+L
Sbjct: 783 KK--------LMNECDHLKESL 796
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sapiens]
Length = 823
Score = 217 bits (552), Expect = 6e-56
Identities = 145/435 (33%), Positives = 246/435 (56%), Gaps = 29/435 (6%)
Query: 594 NHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI---LELEKELCSLRFAIQQEKK 650
N E++++ + +S R++++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 651 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ-VSETDE 709
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N+ +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEE 506
Query: 710 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNGET 767
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K N E
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 768 LAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSS 827
+ +T Y +L L ENT L ++L K++ES++RLE +++SY+ RL AA H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 828 KRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALK 882
+R+ +LA + T D ++ + L+ QLS+ + K LK + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 883 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 938
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 939 QLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKEC 998
QLDD K D++E + NIQ E K L+LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 999 QYEKEKAEREVAVRQ 1013
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
Score = 45.8 bits (107), Expect = 2e-04
Identities = 118/622 (18%), Positives = 234/622 (37%), Gaps = 128/622 (20%)
Query: 242 EDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQP 301
+D LN+A ++ EK E PG + + I G+ +G K P
Sbjct: 289 DDKDLNVATKQCVPEKVS----EPLPGSSHEKGNR-----IVNGQGEGPPA------KHP 333
Query: 302 SLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSG 361
SLK + TE +D + G V + L+A +P ++ Q+
Sbjct: 334 SLKPS-----------TEVEDPAVKGAVQRKNVQTLRAE-------QALPVASEEEQERH 375
Query: 362 TVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIARE 421
S +KQP ++K+G T S++ + D S + A
Sbjct: 376 ERSEKKQP-----------------QVKEG--NNTNKSEKIQLSENICDSTSSAA--AGR 414
Query: 422 IKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKD 481
+ K G PQ+ F KK+ + + + T + + +E K+
Sbjct: 415 LTQQRKIGKTYPQQ-------FPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKE 467
Query: 482 SVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSS 541
+ K+++ P Q LEM S+ + N P H+ +++ ++ +
Sbjct: 468 KQYKKEVEAKQLE---PTVQSLEMKSKTAR--------NTP--NRDFHNHEEMKGLMDEN 514
Query: 542 QTVSEDGDSL---CCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQ 598
+ D L C KN D E + K + +K T ++ IKL + +
Sbjct: 515 CILKADIAILRQEICTMKN-----DNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE 569
Query: 599 ----LRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRN 654
+ ++ LK + + L + +++E K +L+ +I + L + + K RN
Sbjct: 570 TAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERN 629
Query: 655 VEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLL 714
++ ++ R+ ++ +++ I E + Q+SET K + L
Sbjct: 630 LKLALERTRD--------VSVQVEMSSAISKVKDENEF-------LTEQLSETQIKFNAL 674
Query: 715 HEN-RLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIA 773
+ R +D + + L +T++N D +++ +++ K + +N E
Sbjct: 675 KDKFRKTRDSLRKKSLALETVQN---------DLSQTQQQTQEM-KEMYQNAEAKVNNST 724
Query: 774 ----CYSGQLAALTDENTTLRSKLE--KQRESRQRLETEMQSYRCRLNAARCDHDQSHSS 827
C ++ L EN L +L+ Q+E + + T +Q R + + + D S
Sbjct: 725 GKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQ--RGFIESGKKDLVLEEKS 782
Query: 828 KRDQELAFQGTVDKCRHLQENL 849
K+ +++C HL+E+L
Sbjct: 783 KK--------LMNECDHLKESL 796
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 217 bits (552), Expect = 6e-56
Identities = 145/435 (33%), Positives = 246/435 (56%), Gaps = 29/435 (6%)
Query: 594 NHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI---LELEKELCSLRFAIQQEKK 650
N E++++ + +S R++++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 651 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSN-QVSETDE 709
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEE 506
Query: 710 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNGET 767
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K N E
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 768 LAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSS 827
+ +T Y +L L ENT L ++L K++ES++RLE +++SY+ RL AA H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 828 KRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALK 882
+R+ +LA + T D ++ + + L+ QLS+ + K LK + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKAENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 883 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 938
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 939 QLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKEC 998
QLDD K D++E + NIQ E K L+LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 999 QYEKEKAEREVAVRQ 1013
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
Score = 47.0 bits (110), Expect = 1e-04
Identities = 123/622 (19%), Positives = 235/622 (37%), Gaps = 128/622 (20%)
Query: 242 EDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQP 301
+D LN+A ++ EK E PG + + I G+ +G K P
Sbjct: 289 DDKDLNVATKQCVPEKVS----EPLPGSSHEKGNR-----IVNGQGEGPPA------KHP 333
Query: 302 SLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSG 361
SLK + TE +D + G V + L+A +P ++ Q+
Sbjct: 334 SLKPS-----------TEVEDPAVKGAVQRKNVQTLRAE-------QALPVASEEEQERH 375
Query: 362 TVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIARE 421
S +KQP ++K+G T S++ + D S + A
Sbjct: 376 ERSEKKQP-----------------QVKEG--NNTNKSEKIQLSENICDSTSSAA--AGR 414
Query: 422 IKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKD 481
+ K G PQ+ F KK+ + + + T + + +E K+
Sbjct: 415 LTQQRKIGKTYPQQ-------FPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKE 467
Query: 482 SVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSS 541
+ K+++ P Q LEM S+ + N P H+ +++ ++ +
Sbjct: 468 KQYKKEVEAKQLE---PTVQSLEMKSKTAR--------NTPNW--DFHNHEEMKGLMDEN 514
Query: 542 QTVSEDGDSL---CCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQ 598
+ D L C KN D E + K + +K T ++ IKL + +
Sbjct: 515 CILKADIAILRQEICTMKN-----DNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE 569
Query: 599 ----LRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRN 654
+ ++ LK + + L + +++E K +L+ +I + L + + K RN
Sbjct: 570 TAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERN 629
Query: 655 VEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLL 714
+ + E+ R Q + + ++K AE E T Q+SET K + L
Sbjct: 630 L----KLALERTRDVSVQVEMSSAISK------VKAENEFLT-----EQLSETQIKFNAL 674
Query: 715 HEN-RLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIA 773
+ R +D + + L +T++N D +++ +++ K + +N E
Sbjct: 675 KDKFRKTRDSLRKKSLALETVQN---------DLSQTQQQTQEM-KEMYQNAEAKVNNST 724
Query: 774 ----CYSGQLAALTDENTTLRSKLE--KQRESRQRLETEMQSYRCRLNAARCDHDQSHSS 827
C ++ L EN L +L+ Q+E + + T +Q R + + + D S
Sbjct: 725 GKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQ--RGFIESGKKDLVLEEKS 782
Query: 828 KRDQELAFQGTVDKCRHLQENL 849
K+ +++C HL+E+L
Sbjct: 783 KK--------LMNECDHLKESL 796
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 214 bits (545), Expect = 4e-55
Identities = 144/435 (33%), Positives = 243/435 (55%), Gaps = 29/435 (6%)
Query: 594 NHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI---LELEKELCSLRFAIQQEKK 650
N E++++ + +S R++++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 651 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSN-QVSETDE 709
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEE 506
Query: 710 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNGET 767
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K N E
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 768 LAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSS 827
+ +T Y +L L ENT L ++L K++ES++RLE +++SY+ RL AA H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 828 KRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALK 882
+R+ +LA + T D ++ + L+ QLS+ + K LK + T ++L+
Sbjct: 627 ERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 883 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 938
+K+L E VQ+ L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 939 QLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKEC 998
QLDD K D++E + NIQ E K +LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDFVLEEKSKKLMNECDHLKESLF 797
Query: 999 QYEKEKAEREVAVRQ 1013
QYE+EK E V++++
Sbjct: 798 QYEREKTEVVVSIKE 812
Score = 45.8 bits (107), Expect = 2e-04
Identities = 125/619 (20%), Positives = 235/619 (37%), Gaps = 122/619 (19%)
Query: 242 EDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQP 301
+D LN+A ++ EK E PG + + I G+ +G K P
Sbjct: 289 DDKDLNVATKQCVPEKVS----EPLPGSSHEKGNR-----IVNGQGEGPPA------KHP 333
Query: 302 SLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSG 361
SLK + TE +D + G V + L+A +P ++ QQ
Sbjct: 334 SLKPS-----------TEVEDPAVKGAVQRKNVQTLRAE-------QALPVASEEEQQRH 375
Query: 362 TVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIARE 421
S +KQP ++K+G T S++ + D S + A
Sbjct: 376 ERSEKKQP-----------------QVKEG--NNTNKSEKIQLSENICDSTSSAA--AGR 414
Query: 422 IKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKD 481
+ K G PQ+ F KK+ + + + T + + +E K+
Sbjct: 415 LTQQRKIGKTYPQQ-------FPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKE 467
Query: 482 SVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSS 541
+ K+++ P Q LEM S+ + N P H+ +++ ++ +
Sbjct: 468 KQYKKEVEAKQLE---PTVQSLEMKSKTAR--------NTPNW--DFHNHEEMKGLMDEN 514
Query: 542 QTVSEDGDSL---CCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQ 598
+ D L C KN D E + K + +K T ++ IKL + +
Sbjct: 515 CILKADIAILRQEICTMKN-----DNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE 569
Query: 599 ----LRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRN 654
+ ++ LK + + L + +++E K +L+ +I + L + + K RN
Sbjct: 570 TAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERN 629
Query: 655 VEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGN-NSNQVSETDEKEDL 713
+ KL + Q DV+ ++ + SA ++K + Q+SET K +
Sbjct: 630 L---------KLALERTQ-----DVS--VQVEMSSAISKVKDENEFLTEQLSETQIKFNA 673
Query: 714 LHEN-RLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTI 772
L + R +D + + L +T++N NL + + E+ + K G+
Sbjct: 674 LKDKFRKTRDSLRKKSLALETVQN-NLSQTQQQTQEMKEMYQNAEAKVNNSTGKW----- 727
Query: 773 ACYSGQLAALTDENTTLRSKLE--KQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRD 830
C ++ L EN L +L+ Q+E + + T +Q R + + + D SK+
Sbjct: 728 NCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQ--RGFIESGKKDFVLEEKSKK- 784
Query: 831 QELAFQGTVDKCRHLQENL 849
+++C HL+E+L
Sbjct: 785 -------LMNECDHLKESL 796
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 207 bits (526), Expect = 6e-53
Identities = 159/508 (31%), Positives = 274/508 (53%), Gaps = 40/508 (7%)
Query: 627 LKHEILELEKELCSLRFAIQQEKKKRRNVEELHQ-KVREKLRITEEQYRIEADVTKPIKP 685
++ +ILE + ++ ++ E L + K R+KL+ +E + E + +K
Sbjct: 347 IQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHN----LKV 402
Query: 686 ALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLMQDEIARLRLEKDTIKNQNL--EKK 742
A + + L+ N Q S++ +K+D + N +++ +IA L+ E IKN +L EKK
Sbjct: 403 ASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKK 462
Query: 743 YLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQR 802
Y+++ + + + + +K+++ N E + K +A YS QL L EN L SKLEK++ +++R
Sbjct: 463 YIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKER 522
Query: 803 LETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------I 855
LE E++S L A ++++ ++D EL D RH E + S++ +
Sbjct: 523 LEAEVESLHSNLATAINEYNEI-LERKDLELVLWRADDVSRH--ETMGSNISQLTDKNEL 579
Query: 856 LSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNT 915
L+ Q+ KA K LK +L T +AL+EK L E VQ +LKQ Q ++K++++M+ +G
Sbjct: 580 LTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAK 639
Query: 916 MEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAE 971
+ I KQ ER Q + +N+LL++QL+DAR + DN+E ++NI C ++N + +
Sbjct: 640 ESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKE-IVINIHRDC---LENGKED 695
Query: 972 CRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKAL 1031
LLEE NK L+NE N+ KEK QYEKEKAEREV VR+ Q++ D L K S +++
Sbjct: 696 ------LLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESP 749
Query: 1032 LDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMM 1091
L+ +S HC + S+KKL Q+ Q +E ++ + ++
Sbjct: 750 LEGTS-HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQI------- 801
Query: 1092 RKIIKKQDDQIERLEKILQHSSLMLQVF 1119
RK ++ +++ +K L+ + ML F
Sbjct: 802 RKKNRELEEEATGYKKCLEMTINMLNAF 829
Score = 61.6 bits (148), Expect = 4e-09
Identities = 140/698 (20%), Positives = 285/698 (40%), Gaps = 119/698 (17%)
Query: 436 QSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQT 495
+S Q+ I + K +L R ++ PENL+ K K+K+ +
Sbjct: 345 RSIQQQILEHKNKMLKNHLR-NDNQETAAMKPENLKKRKKR-----------KKLKKRKE 392
Query: 496 STPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNC 555
AE +L++ASE +Q+RLE EN QP Q SQ+ + D + N
Sbjct: 393 GAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKKDEMFGN- 435
Query: 556 KNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASV--- 612
+LK ++ L + L +K++ + + I+++K+ +
Sbjct: 436 ------------------FMLK-RDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINAN 476
Query: 613 LQKRISEKEEI----KSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRI 668
+K + EE+ +Q ++ +L+ E L +++EK + +E + + L
Sbjct: 477 FEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLAT 536
Query: 669 TEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENRLMQDEI- 724
+Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R+ + +
Sbjct: 537 AINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLK 595
Query: 725 ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNGETL-AKTIACYSGQLAAL 782
+LR +D ++ + L + ++ D + + + +++ K + NGE +++I + +
Sbjct: 596 GKLRETRDALREKTLALESVQLDLKQAQHRIKEM-KQMHPNGEAKESQSIGKQNSSEERI 654
Query: 783 TD---ENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTV 839
EN L +LE R+ E + +R L + + +R++EL +
Sbjct: 655 RQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGK----EDLLEERNKEL-----M 705
Query: 840 DKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQ 899
++ +L+E L LQ K +++ V+ E E L + F +S L+
Sbjct: 706 NEYNYLKEKL--------LQYEKEKAEREVIVREFQ---EELVDHLKKFSMSESPLEGTS 754
Query: 900 SQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILN 956
++++ + S + I EK E F ++ + LL D R K N+E
Sbjct: 755 HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--NRE----- 807
Query: 957 IQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQ 1016
L+ E ++ LE ML N ++ + ++ ++L+Q
Sbjct: 808 -----------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQ 856
Query: 1017 KRDDVLNKGSATKA-----LLDASSRHCTYLENG-MQDSRKKLDQMRSQFQEIQDQLTAT 1070
K DD++ + A + D H L G +Q+ +KL++ + +E
Sbjct: 857 KFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE------KV 910
Query: 1071 IRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKI 1108
+ ME D +L ++ ++ IE+LE+I
Sbjct: 911 LNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 948
Score = 35.4 bits (80), Expect = 0.31
Identities = 111/599 (18%), Positives = 231/599 (38%), Gaps = 76/599 (12%)
Query: 189 KSGTVSSQKK--PALKATSDEKDSFSNITREKKDGEISRTVS--SQKPPALKATSVKEDS 244
K+ ++ +KK +K+ ++ +F R ++ I++ V+ SQ+ LKA + + +S
Sbjct: 453 KNDSLRKEKKYIQEIKSITEINANFEKSVRLNEE-MITKKVAQYSQQLNDLKAENARLNS 511
Query: 245 VLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGE----KTRRVSSHKQ 300
L + K+ ++ S L +E + +L +KD E + VS H+
Sbjct: 512 KLEKEKHNKERLEAEVESLHS--NLATAINEYNEILE----RKDLELVLWRADDVSRHET 565
Query: 301 --PSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQ 358
++ +DK + + + + + T+ + + A +K ++ ++ ++K Q
Sbjct: 566 MGSNISQLTDKNELLTEQVHKARVK--FNTLKGKLRETRDALREKTLALESVQLDLKQAQ 623
Query: 359 QSGTVSSQKQPAWKATSVKKDSVSNIATE-IKDGQIRGTVSSQRRPALKTTGDEKDSVSN 417
Q P +A + N + E I+ ++ + ++ + GD K+ V N
Sbjct: 624 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVIN 683
Query: 418 IAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENL------- 470
I R+ + K + + + K LL E+ E L
Sbjct: 684 IHRDCLENGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKF 743
Query: 471 ----RTLKATIE---NKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQ 523
L+ T N D + K+ +V+ P E+ E E L Y +Q +
Sbjct: 744 SMSESPLEGTSHCHINLDETWTSKKKLFQVEIQ-PEEKHEEFRKVFELISLLNYTADQIR 802
Query: 524 VKNQIHSRDD------LDDIIQ-----SSQTVSEDGDSLCCNCKNVIL----------LI 562
KN+ + L+ I +++ S GD K IL L+
Sbjct: 803 KKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLM 862
Query: 563 DQHEMKCKDCVHLLKIKNTFCLWKRLIKLK--DNHCEQLRVKIRKLKNKASVLQKRISEK 620
+ E CV+L K L + L+ + CE+L + L+ K L+ + +
Sbjct: 863 AEKEAVSSKCVNLAKDNEV--LHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKD 920
Query: 621 -------EEIKSQLKHEILELEKELCSLRFAIQQEKKKRR---NVEELHQKVREKLRITE 670
+E KS+L ++ ++L + Q E +K+ N + +++L + +
Sbjct: 921 MVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKD 980
Query: 671 EQYRIEA------DVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDE 723
+ + DVT ++ ++ V LK + S +++++D+K ++ M+ E
Sbjct: 981 VECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKE 1039
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 207 bits (526), Expect = 6e-53
Identities = 159/508 (31%), Positives = 274/508 (53%), Gaps = 40/508 (7%)
Query: 627 LKHEILELEKELCSLRFAIQQEKKKRRNVEELHQ-KVREKLRITEEQYRIEADVTKPIKP 685
++ +ILE + ++ ++ E L + K R+KL+ +E + E + +K
Sbjct: 376 IQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHN----LKV 431
Query: 686 ALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLMQDEIARLRLEKDTIKNQNL--EKK 742
A + + L+ N Q S++ +K+D + N +++ +IA L+ E IKN +L EKK
Sbjct: 432 ASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKK 491
Query: 743 YLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQR 802
Y+++ + + + + +K+++ N E + K +A YS QL L EN L SKLEK++ +++R
Sbjct: 492 YIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKER 551
Query: 803 LETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------I 855
LE E++S L A ++++ ++D EL D RH E + S++ +
Sbjct: 552 LEAEVESLHSNLATAINEYNEI-LERKDLELVLWRADDVSRH--ETMGSNISQLTDKNEL 608
Query: 856 LSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNT 915
L+ Q+ KA K LK +L T +AL+EK L E VQ +LKQ Q ++K++++M+ +G
Sbjct: 609 LTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAK 668
Query: 916 MEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAE 971
+ I KQ ER Q + +N+LL++QL+DAR + DN+E ++NI C ++N + +
Sbjct: 669 ESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKE-IVINIHRDC---LENGKED 724
Query: 972 CRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKAL 1031
LLEE NK L+NE N+ KEK QYEKEKAEREV VR+ Q++ D L K S +++
Sbjct: 725 ------LLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESP 778
Query: 1032 LDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMM 1091
L+ +S HC + S+KKL Q+ Q +E ++ + ++
Sbjct: 779 LEGTS-HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQI------- 830
Query: 1092 RKIIKKQDDQIERLEKILQHSSLMLQVF 1119
RK ++ +++ +K L+ + ML F
Sbjct: 831 RKKNRELEEEATGYKKCLEMTINMLNAF 858
Score = 61.6 bits (148), Expect = 4e-09
Identities = 140/698 (20%), Positives = 285/698 (40%), Gaps = 119/698 (17%)
Query: 436 QSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQT 495
+S Q+ I + K +L R ++ PENL+ K K+K+ +
Sbjct: 374 RSIQQQILEHKNKMLKNHLR-NDNQETAAMKPENLKKRKKR-----------KKLKKRKE 421
Query: 496 STPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNC 555
AE +L++ASE +Q+RLE EN QP Q SQ+ + D + N
Sbjct: 422 GAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKKDEMFGN- 464
Query: 556 KNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASV--- 612
+LK ++ L + L +K++ + + I+++K+ +
Sbjct: 465 ------------------FMLK-RDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINAN 505
Query: 613 LQKRISEKEEI----KSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRI 668
+K + EE+ +Q ++ +L+ E L +++EK + +E + + L
Sbjct: 506 FEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLAT 565
Query: 669 TEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENRLMQDEI- 724
+Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R+ + +
Sbjct: 566 AINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLK 624
Query: 725 ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNGETL-AKTIACYSGQLAAL 782
+LR +D ++ + L + ++ D + + + +++ K + NGE +++I + +
Sbjct: 625 GKLRETRDALREKTLALESVQLDLKQAQHRIKEM-KQMHPNGEAKESQSIGKQNSSEERI 683
Query: 783 TD---ENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTV 839
EN L +LE R+ E + +R L + + +R++EL +
Sbjct: 684 RQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGK----EDLLEERNKEL-----M 734
Query: 840 DKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQ 899
++ +L+E L LQ K +++ V+ E E L + F +S L+
Sbjct: 735 NEYNYLKEKL--------LQYEKEKAEREVIVREFQ---EELVDHLKKFSMSESPLEGTS 783
Query: 900 SQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILN 956
++++ + S + I EK E F ++ + LL D R K N+E
Sbjct: 784 HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--NRE----- 836
Query: 957 IQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQ 1016
L+ E ++ LE ML N ++ + ++ ++L+Q
Sbjct: 837 -----------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQ 885
Query: 1017 KRDDVLNKGSATKA-----LLDASSRHCTYLENG-MQDSRKKLDQMRSQFQEIQDQLTAT 1070
K DD++ + A + D H L G +Q+ +KL++ + +E
Sbjct: 886 KFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE------KV 939
Query: 1071 IRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKI 1108
+ ME D +L ++ ++ IE+LE+I
Sbjct: 940 LNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 977
Score = 35.4 bits (80), Expect = 0.31
Identities = 111/599 (18%), Positives = 231/599 (38%), Gaps = 76/599 (12%)
Query: 189 KSGTVSSQKK--PALKATSDEKDSFSNITREKKDGEISRTVS--SQKPPALKATSVKEDS 244
K+ ++ +KK +K+ ++ +F R ++ I++ V+ SQ+ LKA + + +S
Sbjct: 482 KNDSLRKEKKYIQEIKSITEINANFEKSVRLNEE-MITKKVAQYSQQLNDLKAENARLNS 540
Query: 245 VLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGE----KTRRVSSHKQ 300
L + K+ ++ S L +E + +L +KD E + VS H+
Sbjct: 541 KLEKEKHNKERLEAEVESLHS--NLATAINEYNEILE----RKDLELVLWRADDVSRHET 594
Query: 301 --PSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQ 358
++ +DK + + + + + T+ + + A +K ++ ++ ++K Q
Sbjct: 595 MGSNISQLTDKNELLTEQVHKARVK--FNTLKGKLRETRDALREKTLALESVQLDLKQAQ 652
Query: 359 QSGTVSSQKQPAWKATSVKKDSVSNIATE-IKDGQIRGTVSSQRRPALKTTGDEKDSVSN 417
Q P +A + N + E I+ ++ + ++ + GD K+ V N
Sbjct: 653 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVIN 712
Query: 418 IAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENL------- 470
I R+ + K + + + K LL E+ E L
Sbjct: 713 IHRDCLENGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKF 772
Query: 471 ----RTLKATIE---NKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQ 523
L+ T N D + K+ +V+ P E+ E E L Y +Q +
Sbjct: 773 SMSESPLEGTSHCHINLDETWTSKKKLFQVEIQ-PEEKHEEFRKVFELISLLNYTADQIR 831
Query: 524 VKNQIHSRDD------LDDIIQ-----SSQTVSEDGDSLCCNCKNVIL----------LI 562
KN+ + L+ I +++ S GD K IL L+
Sbjct: 832 KKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLM 891
Query: 563 DQHEMKCKDCVHLLKIKNTFCLWKRLIKLK--DNHCEQLRVKIRKLKNKASVLQKRISEK 620
+ E CV+L K L + L+ + CE+L + L+ K L+ + +
Sbjct: 892 AEKEAVSSKCVNLAKDNEV--LHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKD 949
Query: 621 -------EEIKSQLKHEILELEKELCSLRFAIQQEKKKRR---NVEELHQKVREKLRITE 670
+E KS+L ++ ++L + Q E +K+ N + +++L + +
Sbjct: 950 MVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKD 1009
Query: 671 EQYRIEA------DVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDE 723
+ + DVT ++ ++ V LK + S +++++D+K ++ M+ E
Sbjct: 1010 VECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKE 1068
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 207 bits (526), Expect = 6e-53
Identities = 159/508 (31%), Positives = 274/508 (53%), Gaps = 40/508 (7%)
Query: 627 LKHEILELEKELCSLRFAIQQEKKKRRNVEELHQ-KVREKLRITEEQYRIEADVTKPIKP 685
++ +ILE + ++ ++ E L + K R+KL+ +E + E + +K
Sbjct: 376 IQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHN----LKV 431
Query: 686 ALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLMQDEIARLRLEKDTIKNQNL--EKK 742
A + + L+ N Q S++ +K+D + N +++ +IA L+ E IKN +L EKK
Sbjct: 432 ASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKK 491
Query: 743 YLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQR 802
Y+++ + + + + +K+++ N E + K +A YS QL L EN L SKLEK++ +++R
Sbjct: 492 YIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKER 551
Query: 803 LETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------I 855
LE E++S L A ++++ ++D EL D RH E + S++ +
Sbjct: 552 LEAEVESLHSNLATAINEYNEI-LERKDLELVLWRADDVSRH--ETMGSNISQLTDKNEL 608
Query: 856 LSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNT 915
L+ Q+ KA K LK +L T +AL+EK L E VQ +LKQ Q ++K++++M+ +G
Sbjct: 609 LTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAK 668
Query: 916 MEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAE 971
+ I KQ ER Q + +N+LL++QL+DAR + DN+E ++NI C ++N + +
Sbjct: 669 ESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKE-IVINIHRDC---LENGKED 724
Query: 972 CRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKAL 1031
LLEE NK L+NE N+ KEK QYEKEKAEREV VR+ Q++ D L K S +++
Sbjct: 725 ------LLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESP 778
Query: 1032 LDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMM 1091
L+ +S HC + S+KKL Q+ Q +E ++ + ++
Sbjct: 779 LEGTS-HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQI------- 830
Query: 1092 RKIIKKQDDQIERLEKILQHSSLMLQVF 1119
RK ++ +++ +K L+ + ML F
Sbjct: 831 RKKNRELEEEATGYKKCLEMTINMLNAF 858
Score = 61.6 bits (148), Expect = 4e-09
Identities = 140/698 (20%), Positives = 285/698 (40%), Gaps = 119/698 (17%)
Query: 436 QSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQT 495
+S Q+ I + K +L R ++ PENL+ K K+K+ +
Sbjct: 374 RSIQQQILEHKNKMLKNHLR-NDNQETAAMKPENLKKRKKR-----------KKLKKRKE 421
Query: 496 STPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNC 555
AE +L++ASE +Q+RLE EN QP Q SQ+ + D + N
Sbjct: 422 GAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKKDEMFGN- 464
Query: 556 KNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASV--- 612
+LK ++ L + L +K++ + + I+++K+ +
Sbjct: 465 ------------------FMLK-RDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINAN 505
Query: 613 LQKRISEKEEI----KSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRI 668
+K + EE+ +Q ++ +L+ E L +++EK + +E + + L
Sbjct: 506 FEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLAT 565
Query: 669 TEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENRLMQDEI- 724
+Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R+ + +
Sbjct: 566 AINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLK 624
Query: 725 ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNGETL-AKTIACYSGQLAAL 782
+LR +D ++ + L + ++ D + + + +++ K + NGE +++I + +
Sbjct: 625 GKLRETRDALREKTLALESVQLDLKQAQHRIKEM-KQMHPNGEAKESQSIGKQNSSEERI 683
Query: 783 TD---ENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTV 839
EN L +LE R+ E + +R L + + +R++EL +
Sbjct: 684 RQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGK----EDLLEERNKEL-----M 734
Query: 840 DKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQ 899
++ +L+E L LQ K +++ V+ E E L + F +S L+
Sbjct: 735 NEYNYLKEKL--------LQYEKEKAEREVIVREFQ---EELVDHLKKFSMSESPLEGTS 783
Query: 900 SQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILN 956
++++ + S + I EK E F ++ + LL D R K N+E
Sbjct: 784 HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--NRE----- 836
Query: 957 IQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQ 1016
L+ E ++ LE ML N ++ + ++ ++L+Q
Sbjct: 837 -----------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQ 885
Query: 1017 KRDDVLNKGSATKA-----LLDASSRHCTYLENG-MQDSRKKLDQMRSQFQEIQDQLTAT 1070
K DD++ + A + D H L G +Q+ +KL++ + +E
Sbjct: 886 KFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE------KV 939
Query: 1071 IRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKI 1108
+ ME D +L ++ ++ IE+LE+I
Sbjct: 940 LNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 977
Score = 35.4 bits (80), Expect = 0.31
Identities = 111/599 (18%), Positives = 231/599 (38%), Gaps = 76/599 (12%)
Query: 189 KSGTVSSQKK--PALKATSDEKDSFSNITREKKDGEISRTVS--SQKPPALKATSVKEDS 244
K+ ++ +KK +K+ ++ +F R ++ I++ V+ SQ+ LKA + + +S
Sbjct: 482 KNDSLRKEKKYIQEIKSITEINANFEKSVRLNEE-MITKKVAQYSQQLNDLKAENARLNS 540
Query: 245 VLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGE----KTRRVSSHKQ 300
L + K+ ++ S L +E + +L +KD E + VS H+
Sbjct: 541 KLEKEKHNKERLEAEVESLHS--NLATAINEYNEILE----RKDLELVLWRADDVSRHET 594
Query: 301 --PSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQ 358
++ +DK + + + + + T+ + + A +K ++ ++ ++K Q
Sbjct: 595 MGSNISQLTDKNELLTEQVHKARVK--FNTLKGKLRETRDALREKTLALESVQLDLKQAQ 652
Query: 359 QSGTVSSQKQPAWKATSVKKDSVSNIATE-IKDGQIRGTVSSQRRPALKTTGDEKDSVSN 417
Q P +A + N + E I+ ++ + ++ + GD K+ V N
Sbjct: 653 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVIN 712
Query: 418 IAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENL------- 470
I R+ + K + + + K LL E+ E L
Sbjct: 713 IHRDCLENGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKF 772
Query: 471 ----RTLKATIE---NKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQ 523
L+ T N D + K+ +V+ P E+ E E L Y +Q +
Sbjct: 773 SMSESPLEGTSHCHINLDETWTSKKKLFQVEIQ-PEEKHEEFRKVFELISLLNYTADQIR 831
Query: 524 VKNQIHSRDD------LDDIIQ-----SSQTVSEDGDSLCCNCKNVIL----------LI 562
KN+ + L+ I +++ S GD K IL L+
Sbjct: 832 KKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLM 891
Query: 563 DQHEMKCKDCVHLLKIKNTFCLWKRLIKLK--DNHCEQLRVKIRKLKNKASVLQKRISEK 620
+ E CV+L K L + L+ + CE+L + L+ K L+ + +
Sbjct: 892 AEKEAVSSKCVNLAKDNEV--LHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKD 949
Query: 621 -------EEIKSQLKHEILELEKELCSLRFAIQQEKKKRR---NVEELHQKVREKLRITE 670
+E KS+L ++ ++L + Q E +K+ N + +++L + +
Sbjct: 950 MVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKD 1009
Query: 671 EQYRIEA------DVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDE 723
+ + DVT ++ ++ V LK + S +++++D+K ++ M+ E
Sbjct: 1010 VECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKE 1068
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 196 bits (497), Expect = 1e-49
Identities = 158/530 (29%), Positives = 276/530 (52%), Gaps = 37/530 (6%)
Query: 608 NKASVLQKRISEKEEIKSQ----LKHEILELEKELCSLRFAIQQEKKK--RRNVEELHQK 661
N +S++ + + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 318 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 377
Query: 662 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 720
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 378 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 437
Query: 721 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQ 778
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ N + + KT+A YS Q
Sbjct: 438 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 497
Query: 779 LAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGT 838
L L EN L S+LEK++ +++RLE E++S L A ++++ ++D EL
Sbjct: 498 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 556
Query: 839 VDKCRHLQENLNSHVL-----ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQS 893
D RH + N L +L+ Q+ KA K LK +L T +AL+EK L VQ
Sbjct: 557 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 616
Query: 894 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 949
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 617 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 676
Query: 950 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1009
+E ++NI C ++N + + LLEE NK L+ E N+ KEK Q EKEKAEREV
Sbjct: 677 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 726
Query: 1010 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1069
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 727 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 785
Query: 1070 TIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVF 1119
+ ++ RK ++ +++ +K L+ + ML F
Sbjct: 786 LFELISLLNYTADQI-------RKKNRELEEEATGYKKCLEMTINMLNAF 828
Score = 58.2 bits (139), Expect = 4e-08
Identities = 131/672 (19%), Positives = 277/672 (41%), Gaps = 129/672 (19%)
Query: 478 ENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDI 537
+N+++ +K+ + AE +L++ASE +Q+RL+ EN QP
Sbjct: 374 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQP--------------- 418
Query: 538 IQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCE 597
Q SQ+ + D++ N +LK K+ L + L +K++
Sbjct: 419 -QDSQSYGKKKDAMYGN-------------------FMLK-KDIAMLKEELYAIKNDSLR 457
Query: 598 QLRVKIRKLKNKASV-----LQKRISEKEEIKSQLKH--EILELEKELCSLRFAIQQEKK 650
+ + I+++K+ + R++EK K+ ++ ++ +L+ E L +++EK
Sbjct: 458 KEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKH 517
Query: 651 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEK 710
+ +E + + L +Y E K ++ L A+ ++ + +S+ +K
Sbjct: 518 NKERLEAEVESLHSSLATAINEYN-EIVERKDLELVLWRAD-DVSRHEKMGSNISQLTDK 575
Query: 711 EDLL----HENRLMQDEI-ARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKR-- 763
+LL H+ R+ + + +LR +D ++ + L L ++ R+ + K +K+
Sbjct: 576 NELLTEQVHKARVKFNTLKGKLRETRDALREKTLA---LGSVQLDLRQAQHRIKEMKQMH 632
Query: 764 -NGETL-AKTIACYSG---QLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAAR 818
NGE +++I + ++ EN L +LE R+ E + +R L +
Sbjct: 633 PNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGK 692
Query: 819 CDHDQSHSSKRDQELAF------QGTVDKC------RHLQENLNSHVLILSLQLSKAE-- 864
D + + + +E + Q +K R QE L H+ S+ S E
Sbjct: 693 EDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGT 752
Query: 865 ------------SKSRVLKTEL-----HYTGEALKEKALVFEHVQSELKQKQSQMKDIEK 907
SK ++ + E+ H L E + + ++++K ++++
Sbjct: 753 SHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEAT 812
Query: 908 MYKSGYN---TMEKCIEKQERFC-------QLKKQNML--LQQQLDDARNKADNQEKAIL 955
YK M ++ C QLK + L+Q+ +D + + +
Sbjct: 813 GYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECV 872
Query: 956 NIQARCDA------RVQNLQAECRKHRLLLEEDNKMLVNELNHSK---EKEC-------Q 999
N+ + ++N+Q +C K LE+D KML E+ + K EK+ +
Sbjct: 873 NLAKDNEVLHQELLSMRNVQEKCEK----LEKDKKMLEEEVLNLKTHMEKDMVELGKLQE 928
Query: 1000 YEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT----YLENGMQDSRKKLDQ 1055
Y+ E ER AV+++++ + L K + + L+ ++ T E ++D K +
Sbjct: 929 YKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSK 986
Query: 1056 MRSQFQEIQDQL 1067
M++ ++E+ +L
Sbjct: 987 MKTAYEEVTTEL 998
Score = 35.8 bits (81), Expect = 0.23
Identities = 114/556 (20%), Positives = 217/556 (39%), Gaps = 101/556 (18%)
Query: 461 KSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENN 520
K+ Y + L LKA +S L KE E ++E + EY
Sbjct: 489 KTVARYSQQLNDLKAENARLNSELE-----KEKHNKERLEAEVESLHSSLATAINEY--- 540
Query: 521 QPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK- 579
N+I R DL+ ++ + VS N+ L D++E+ + VH ++K
Sbjct: 541 -----NEIVERKDLELVLWRADDVSRHEKM----GSNISQLTDKNELLTEQ-VHKARVKF 590
Query: 580 NTF---------CLWKRLIKLKDNHCE--QLRVKIRKLKN--------------KASVLQ 614
NT L ++ + L + Q + +I+++K K + L+
Sbjct: 591 NTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLE 650
Query: 615 KRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 674
+RI ++E L+ ++ + KE + I + N +E + R K + E Y
Sbjct: 651 ERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYL 710
Query: 675 ----IEADVTKPIKPALKSAEVELKTGGNNSNQVSETD-EKEDLLHENRLMQDEIARLRL 729
++ + K + + E + +SE+ E H N L + ++ +L
Sbjct: 711 KEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHIN-LNETWTSKKKL 769
Query: 730 EKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGET------LAKTIACYSGQLAALT 783
+ I+ + +++ K FE++ + + K+N E K + L A
Sbjct: 770 FQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFA 829
Query: 784 DENTTLRSKLE-------------KQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRD 830
+E+ + L KQ+ + E E S C +N A+ D++ H
Sbjct: 830 NEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSEC-VNLAK-DNEVLHQ---- 883
Query: 831 QELAFQGTVDKCRHLQE----------NLNSH-----VLILSLQLSKAESKSRVLKT--- 872
+ L+ + +KC L++ NL +H V + LQ K+E R ++
Sbjct: 884 ELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEK 943
Query: 873 --ELHYTGEALKEKAL--VFEHVQSELKQKQSQMKDIEKMY---KSGYNTMEKCIEK-QE 924
E+H +A EK L + + + LK+K+ +KD+E + K+ Y + +E+ +E
Sbjct: 944 LEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKE 1003
Query: 925 RFCQLKKQNMLLQQQL 940
F K N + ++L
Sbjct: 1004 AFAGAVKANNSMSKKL 1019
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 196 bits (497), Expect = 1e-49
Identities = 158/530 (29%), Positives = 276/530 (52%), Gaps = 37/530 (6%)
Query: 608 NKASVLQKRISEKEEIKSQ----LKHEILELEKELCSLRFAIQQEKKK--RRNVEELHQK 661
N +S++ + + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 211 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 270
Query: 662 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 720
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 271 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 330
Query: 721 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQ 778
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ N + + KT+A YS Q
Sbjct: 331 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 390
Query: 779 LAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGT 838
L L EN L S+LEK++ +++RLE E++S L A ++++ ++D EL
Sbjct: 391 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 449
Query: 839 VDKCRHLQENLNSHVL-----ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQS 893
D RH + N L +L+ Q+ KA K LK +L T +AL+EK L VQ
Sbjct: 450 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 509
Query: 894 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 949
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 510 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 569
Query: 950 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1009
+E ++NI C ++N + + LLEE NK L+ E N+ KEK Q EKEKAEREV
Sbjct: 570 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 619
Query: 1010 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1069
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 620 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 678
Query: 1070 TIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVF 1119
+ ++ RK ++ +++ +K L+ + ML F
Sbjct: 679 LFELISLLNYTADQI-------RKKNRELEEEATGYKKCLEMTINMLNAF 721
Score = 58.2 bits (139), Expect = 4e-08
Identities = 131/672 (19%), Positives = 277/672 (41%), Gaps = 129/672 (19%)
Query: 478 ENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDI 537
+N+++ +K+ + AE +L++ASE +Q+RL+ EN QP
Sbjct: 267 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQP--------------- 311
Query: 538 IQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCE 597
Q SQ+ + D++ N +LK K+ L + L +K++
Sbjct: 312 -QDSQSYGKKKDAMYGN-------------------FMLK-KDIAMLKEELYAIKNDSLR 350
Query: 598 QLRVKIRKLKNKASV-----LQKRISEKEEIKSQLKH--EILELEKELCSLRFAIQQEKK 650
+ + I+++K+ + R++EK K+ ++ ++ +L+ E L +++EK
Sbjct: 351 KEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKH 410
Query: 651 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEK 710
+ +E + + L +Y E K ++ L A+ ++ + +S+ +K
Sbjct: 411 NKERLEAEVESLHSSLATAINEYN-EIVERKDLELVLWRAD-DVSRHEKMGSNISQLTDK 468
Query: 711 EDLL----HENRLMQDEI-ARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKR-- 763
+LL H+ R+ + + +LR +D ++ + L L ++ R+ + K +K+
Sbjct: 469 NELLTEQVHKARVKFNTLKGKLRETRDALREKTLA---LGSVQLDLRQAQHRIKEMKQMH 525
Query: 764 -NGETL-AKTIACYSG---QLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAAR 818
NGE +++I + ++ EN L +LE R+ E + +R L +
Sbjct: 526 PNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGK 585
Query: 819 CDHDQSHSSKRDQELAF------QGTVDKC------RHLQENLNSHVLILSLQLSKAE-- 864
D + + + +E + Q +K R QE L H+ S+ S E
Sbjct: 586 EDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGT 645
Query: 865 ------------SKSRVLKTEL-----HYTGEALKEKALVFEHVQSELKQKQSQMKDIEK 907
SK ++ + E+ H L E + + ++++K ++++
Sbjct: 646 SHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEAT 705
Query: 908 MYKSGYN---TMEKCIEKQERFC-------QLKKQNML--LQQQLDDARNKADNQEKAIL 955
YK M ++ C QLK + L+Q+ +D + + +
Sbjct: 706 GYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECV 765
Query: 956 NIQARCDA------RVQNLQAECRKHRLLLEEDNKMLVNELNHSK---EKEC-------Q 999
N+ + ++N+Q +C K LE+D KML E+ + K EK+ +
Sbjct: 766 NLAKDNEVLHQELLSMRNVQEKCEK----LEKDKKMLEEEVLNLKTHMEKDMVELGKLQE 821
Query: 1000 YEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT----YLENGMQDSRKKLDQ 1055
Y+ E ER AV+++++ + L K + + L+ ++ T E ++D K +
Sbjct: 822 YKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSK 879
Query: 1056 MRSQFQEIQDQL 1067
M++ ++E+ +L
Sbjct: 880 MKTAYEEVTTEL 891
Score = 35.8 bits (81), Expect = 0.23
Identities = 114/556 (20%), Positives = 217/556 (39%), Gaps = 101/556 (18%)
Query: 461 KSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENN 520
K+ Y + L LKA +S L KE E ++E + EY
Sbjct: 382 KTVARYSQQLNDLKAENARLNSELE-----KEKHNKERLEAEVESLHSSLATAINEY--- 433
Query: 521 QPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK- 579
N+I R DL+ ++ + VS N+ L D++E+ + VH ++K
Sbjct: 434 -----NEIVERKDLELVLWRADDVSRHEKM----GSNISQLTDKNELLTEQ-VHKARVKF 483
Query: 580 NTF---------CLWKRLIKLKDNHCE--QLRVKIRKLKN--------------KASVLQ 614
NT L ++ + L + Q + +I+++K K + L+
Sbjct: 484 NTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLE 543
Query: 615 KRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 674
+RI ++E L+ ++ + KE + I + N +E + R K + E Y
Sbjct: 544 ERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYL 603
Query: 675 ----IEADVTKPIKPALKSAEVELKTGGNNSNQVSETD-EKEDLLHENRLMQDEIARLRL 729
++ + K + + E + +SE+ E H N L + ++ +L
Sbjct: 604 KEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHIN-LNETWTSKKKL 662
Query: 730 EKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGET------LAKTIACYSGQLAALT 783
+ I+ + +++ K FE++ + + K+N E K + L A
Sbjct: 663 FQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFA 722
Query: 784 DENTTLRSKLE-------------KQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRD 830
+E+ + L KQ+ + E E S C +N A+ D++ H
Sbjct: 723 NEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSEC-VNLAK-DNEVLHQ---- 776
Query: 831 QELAFQGTVDKCRHLQE----------NLNSH-----VLILSLQLSKAESKSRVLKT--- 872
+ L+ + +KC L++ NL +H V + LQ K+E R ++
Sbjct: 777 ELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEK 836
Query: 873 --ELHYTGEALKEKAL--VFEHVQSELKQKQSQMKDIEKMY---KSGYNTMEKCIEK-QE 924
E+H +A EK L + + + LK+K+ +KD+E + K+ Y + +E+ +E
Sbjct: 837 LEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKE 896
Query: 925 RFCQLKKQNMLLQQQL 940
F K N + ++L
Sbjct: 897 AFAGAVKANNSMSKKL 912
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 196 bits (497), Expect = 1e-49
Identities = 158/530 (29%), Positives = 276/530 (52%), Gaps = 37/530 (6%)
Query: 608 NKASVLQKRISEKEEIKSQ----LKHEILELEKELCSLRFAIQQEKKK--RRNVEELHQK 661
N +S++ + + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 318 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 377
Query: 662 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 720
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 378 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 437
Query: 721 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQ 778
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ N + + KT+A YS Q
Sbjct: 438 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 497
Query: 779 LAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGT 838
L L EN L S+LEK++ +++RLE E++S L A ++++ ++D EL
Sbjct: 498 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 556
Query: 839 VDKCRHLQENLNSHVL-----ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQS 893
D RH + N L +L+ Q+ KA K LK +L T +AL+EK L VQ
Sbjct: 557 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 616
Query: 894 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 949
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 617 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 676
Query: 950 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1009
+E ++NI C ++N + + LLEE NK L+ E N+ KEK Q EKEKAEREV
Sbjct: 677 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 726
Query: 1010 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1069
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 727 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 785
Query: 1070 TIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVF 1119
+ ++ RK ++ +++ +K L+ + ML F
Sbjct: 786 LFELISLLNYTADQI-------RKKNRELEEEATGYKKCLEMTINMLNAF 828
Score = 58.2 bits (139), Expect = 4e-08
Identities = 131/672 (19%), Positives = 277/672 (41%), Gaps = 129/672 (19%)
Query: 478 ENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDI 537
+N+++ +K+ + AE +L++ASE +Q+RL+ EN QP
Sbjct: 374 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQP--------------- 418
Query: 538 IQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCE 597
Q SQ+ + D++ N +LK K+ L + L +K++
Sbjct: 419 -QDSQSYGKKKDAMYGN-------------------FMLK-KDIAMLKEELYAIKNDSLR 457
Query: 598 QLRVKIRKLKNKASV-----LQKRISEKEEIKSQLKH--EILELEKELCSLRFAIQQEKK 650
+ + I+++K+ + R++EK K+ ++ ++ +L+ E L +++EK
Sbjct: 458 KEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKH 517
Query: 651 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEK 710
+ +E + + L +Y E K ++ L A+ ++ + +S+ +K
Sbjct: 518 NKERLEAEVESLHSSLATAINEYN-EIVERKDLELVLWRAD-DVSRHEKMGSNISQLTDK 575
Query: 711 EDLL----HENRLMQDEI-ARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKR-- 763
+LL H+ R+ + + +LR +D ++ + L L ++ R+ + K +K+
Sbjct: 576 NELLTEQVHKARVKFNTLKGKLRETRDALREKTLA---LGSVQLDLRQAQHRIKEMKQMH 632
Query: 764 -NGETL-AKTIACYSG---QLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAAR 818
NGE +++I + ++ EN L +LE R+ E + +R L +
Sbjct: 633 PNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGK 692
Query: 819 CDHDQSHSSKRDQELAF------QGTVDKC------RHLQENLNSHVLILSLQLSKAE-- 864
D + + + +E + Q +K R QE L H+ S+ S E
Sbjct: 693 EDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGT 752
Query: 865 ------------SKSRVLKTEL-----HYTGEALKEKALVFEHVQSELKQKQSQMKDIEK 907
SK ++ + E+ H L E + + ++++K ++++
Sbjct: 753 SHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEAT 812
Query: 908 MYKSGYN---TMEKCIEKQERFC-------QLKKQNML--LQQQLDDARNKADNQEKAIL 955
YK M ++ C QLK + L+Q+ +D + + +
Sbjct: 813 GYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECV 872
Query: 956 NIQARCDA------RVQNLQAECRKHRLLLEEDNKMLVNELNHSK---EKEC-------Q 999
N+ + ++N+Q +C K LE+D KML E+ + K EK+ +
Sbjct: 873 NLAKDNEVLHQELLSMRNVQEKCEK----LEKDKKMLEEEVLNLKTHMEKDMVELGKLQE 928
Query: 1000 YEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT----YLENGMQDSRKKLDQ 1055
Y+ E ER AV+++++ + L K + + L+ ++ T E ++D K +
Sbjct: 929 YKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSK 986
Query: 1056 MRSQFQEIQDQL 1067
M++ ++E+ +L
Sbjct: 987 MKTAYEEVTTEL 998
Score = 35.8 bits (81), Expect = 0.23
Identities = 114/556 (20%), Positives = 217/556 (39%), Gaps = 101/556 (18%)
Query: 461 KSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENN 520
K+ Y + L LKA +S L KE E ++E + EY
Sbjct: 489 KTVARYSQQLNDLKAENARLNSELE-----KEKHNKERLEAEVESLHSSLATAINEY--- 540
Query: 521 QPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK- 579
N+I R DL+ ++ + VS N+ L D++E+ + VH ++K
Sbjct: 541 -----NEIVERKDLELVLWRADDVSRHEKM----GSNISQLTDKNELLTEQ-VHKARVKF 590
Query: 580 NTF---------CLWKRLIKLKDNHCE--QLRVKIRKLKN--------------KASVLQ 614
NT L ++ + L + Q + +I+++K K + L+
Sbjct: 591 NTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLE 650
Query: 615 KRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 674
+RI ++E L+ ++ + KE + I + N +E + R K + E Y
Sbjct: 651 ERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYL 710
Query: 675 ----IEADVTKPIKPALKSAEVELKTGGNNSNQVSETD-EKEDLLHENRLMQDEIARLRL 729
++ + K + + E + +SE+ E H N L + ++ +L
Sbjct: 711 KEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHIN-LNETWTSKKKL 769
Query: 730 EKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGET------LAKTIACYSGQLAALT 783
+ I+ + +++ K FE++ + + K+N E K + L A
Sbjct: 770 FQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFA 829
Query: 784 DENTTLRSKLE-------------KQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRD 830
+E+ + L KQ+ + E E S C +N A+ D++ H
Sbjct: 830 NEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSEC-VNLAK-DNEVLHQ---- 883
Query: 831 QELAFQGTVDKCRHLQE----------NLNSH-----VLILSLQLSKAESKSRVLKT--- 872
+ L+ + +KC L++ NL +H V + LQ K+E R ++
Sbjct: 884 ELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEK 943
Query: 873 --ELHYTGEALKEKAL--VFEHVQSELKQKQSQMKDIEKMY---KSGYNTMEKCIEK-QE 924
E+H +A EK L + + + LK+K+ +KD+E + K+ Y + +E+ +E
Sbjct: 944 LEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKE 1003
Query: 925 RFCQLKKQNMLLQQQL 940
F K N + ++L
Sbjct: 1004 AFAGAVKANNSMSKKL 1019
>gi|239754871 PREDICTED: similar to Coiled-coil domain-containing
protein 144C [Homo sapiens]
Length = 264
Score = 125 bits (313), Expect = 3e-28
Identities = 71/174 (40%), Positives = 113/174 (64%), Gaps = 14/174 (8%)
Query: 642 RFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNS 701
R ++QE++KR++ + L++K E+L+ EE+Y + ++ + +K LK+ +EL+T N
Sbjct: 91 RLTLKQEEEKRKDADMLYKKGSEELKRKEEEYGKDVEINQQLKRTLKTRAMELRTVRKNL 150
Query: 702 NQ-----------VSETDEKED-LLHENRLMQDEIARLRLEKDTIKNQN--LEKKYLKDF 747
+Q +S + +KE LLHEN ++Q+EIA LRLE DTIK+QN EKKY +D
Sbjct: 151 DQTFGNLHSLRFEISLSHKKEKGLLHENSMLQEEIAMLRLELDTIKHQNEIKEKKYFEDI 210
Query: 748 EIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQ 801
E VK +H++L KA+ N E LAKT+ Y+GQL+ LT EN L S+L+ + +++
Sbjct: 211 ESVKEEHDNLLKAITLNEEALAKTVFQYNGQLSILTTENKMLSSELKNVKHNKE 264
Score = 32.3 bits (72), Expect = 2.6
Identities = 29/127 (22%), Positives = 57/127 (44%), Gaps = 23/127 (18%)
Query: 889 EHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKAD 948
E+ + LKQ++ + KD + +YK G +++ K+E + +++ + QQL +
Sbjct: 88 EYHRLTLKQEEEKRKDADMLYKKGSEELKR---KEEEY----GKDVEINQQL---KRTLK 137
Query: 949 NQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAERE 1008
+ + ++ D NL H L E L+H KEK +E + E
Sbjct: 138 TRAMELRTVRKNLDQTFGNL------HSLRFE-------ISLSHKKEKGLLHENSMLQEE 184
Query: 1009 VAVRQLQ 1015
+A+ +L+
Sbjct: 185 IAMLRLE 191
>gi|239749410 PREDICTED: similar to Coiled-coil domain-containing
protein 144C [Homo sapiens]
Length = 264
Score = 125 bits (313), Expect = 3e-28
Identities = 71/174 (40%), Positives = 113/174 (64%), Gaps = 14/174 (8%)
Query: 642 RFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNS 701
R ++QE++KR++ + L++K E+L+ EE+Y + ++ + +K LK+ +EL+T N
Sbjct: 91 RLTLKQEEEKRKDADMLYKKGSEELKRKEEEYGKDVEINQQLKRTLKTRAMELRTVRKNL 150
Query: 702 NQ-----------VSETDEKED-LLHENRLMQDEIARLRLEKDTIKNQN--LEKKYLKDF 747
+Q +S + +KE LLHEN ++Q+EIA LRLE DTIK+QN EKKY +D
Sbjct: 151 DQTFGNLHSLRFEISLSHKKEKGLLHENSMLQEEIAMLRLELDTIKHQNEIKEKKYFEDI 210
Query: 748 EIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQ 801
E VK +H++L KA+ N E LAKT+ Y+GQL+ LT EN L S+L+ + +++
Sbjct: 211 ESVKEEHDNLLKAITLNEEALAKTVFQYNGQLSILTTENKMLSSELKNVKHNKE 264
Score = 32.3 bits (72), Expect = 2.6
Identities = 29/127 (22%), Positives = 57/127 (44%), Gaps = 23/127 (18%)
Query: 889 EHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKAD 948
E+ + LKQ++ + KD + +YK G +++ K+E + +++ + QQL +
Sbjct: 88 EYHRLTLKQEEEKRKDADMLYKKGSEELKR---KEEEY----GKDVEINQQL---KRTLK 137
Query: 949 NQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAERE 1008
+ + ++ D NL H L E L+H KEK +E + E
Sbjct: 138 TRAMELRTVRKNLDQTFGNL------HSLRFE-------ISLSHKKEKGLLHENSMLQEE 184
Query: 1009 VAVRQLQ 1015
+A+ +L+
Sbjct: 185 IAMLRLE 191
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.123 0.325
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,268,709
Number of Sequences: 37866
Number of extensions: 1717768
Number of successful extensions: 17148
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 287
Number of HSP's successfully gapped in prelim test: 1165
Number of HSP's that attempted gapping in prelim test: 8533
Number of HSP's gapped (non-prelim): 5606
length of query: 1121
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1008
effective length of database: 13,968,660
effective search space: 14080409280
effective search space used: 14080409280
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.