Search of human proteins with 124256496

Search of human proteins with 124256496

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
         (641 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]          1266   0.0  
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]              1130   0.0  
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]              1130   0.0  
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]       1067   0.0  
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]                1050   0.0  
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]      1039   0.0  
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]       815   0.0  
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]                 782   0.0  
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]       562   e-160
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]      314   2e-85
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]                 293   4e-79
gi|48928056 heat shock protein 70kDa family member 13 precursor ...   279   5e-75
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]            278   8e-75
gi|42544159 heat shock 105kD [Homo sapiens]                           274   2e-73
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]          219   5e-57
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]            219   5e-57
gi|38348298 ankyrin repeat domain 45 [Homo sapiens]                    47   7e-05
gi|9910266 kinesin family member 15 [Homo sapiens]                     39   0.015
gi|123317881 germ cell associated 1 isoform 4 [Homo sapiens]           37   0.056
gi|123317861 germ cell associated 1 isoform 2 [Homo sapiens]           37   0.056
gi|31317303 heat shock 70kD protein 12B [Homo sapiens]                 36   0.096
gi|55770834 centromere protein F [Homo sapiens]                        36   0.12 
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    35   0.16 
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]                 32   1.4  
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]                 32   1.4  
gi|210147558 hypothetical protein LOC202051 [Homo sapiens]             32   1.4  
gi|109148552 keratin 3 [Homo sapiens]                                  32   1.8  
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s...    32   2.4  
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s...    32   2.4  
gi|102469034 janus kinase 1 [Homo sapiens]                             32   2.4  

>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
          Length = 641

 Score = 1266 bits (3276), Expect = 0.0
 Identities = 641/641 (100%), Positives = 641/641 (100%)

Query: 1   MATAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ 60
           MATAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ
Sbjct: 1   MATAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ 60

Query: 61  VAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEE 120
           VAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEE
Sbjct: 61  VAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEE 120

Query: 121 ISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTA 180
           ISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTA
Sbjct: 121 ISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTA 180

Query: 181 AAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 240
           AAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV
Sbjct: 181 AAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 240

Query: 241 SHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSIT 300
           SHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSIT
Sbjct: 241 SHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSIT 300

Query: 301 RARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRD 360
           RARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRD
Sbjct: 301 RARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRD 360

Query: 361 LNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNS 420
           LNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNS
Sbjct: 361 LNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNS 420

Query: 421 TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTF 480
           TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTF
Sbjct: 421 TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTF 480

Query: 481 DIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAA 540
           DIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAA
Sbjct: 481 DIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAA 540

Query: 541 KNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKE 600
           KNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKE
Sbjct: 541 KNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKE 600

Query: 601 LEQMCNPIITKLYQGGCTGPACGTGYVPGRPATGPTIEEVD 641
           LEQMCNPIITKLYQGGCTGPACGTGYVPGRPATGPTIEEVD
Sbjct: 601 LEQMCNPIITKLYQGGCTGPACGTGYVPGRPATGPTIEEVD 641


>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
          Length = 641

 Score = 1130 bits (2922), Expect = 0.0
 Identities = 573/640 (89%), Positives = 606/640 (94%), Gaps = 2/640 (0%)

Query: 4   AKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 63
           AK  AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA+
Sbjct: 2   AKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAL 61

Query: 64  NPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISS 123
           NPQNTVFDAKRLIGRKF DPVVQ+DMK WPFQVIN+G KPKV VSYKGE KAFYPEEISS
Sbjct: 62  NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISS 121

Query: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183
           MVLTK+KE AEA+LG+PVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI
Sbjct: 122 MVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 181

Query: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243
           AYGLD+ G+GER+VLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV+HF
Sbjct: 182 AYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHF 241

Query: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRAR 303
           VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQA+LEIDSL+EGIDFYTSITRAR
Sbjct: 242 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRAR 301

Query: 304 FEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNK 363
           FEELC+DLFR TLEPVEKALRDAK+DKA+IHD+VLVGGSTRIPKVQ+LLQD+FNGRDLNK
Sbjct: 302 FEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNK 361

Query: 364 SINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 423
           SINPDEAVAYGAAVQAAILMGDKSE VQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP
Sbjct: 362 SINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 421

Query: 424 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTFDID 483
           TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRF+L+GIPPAPRGVPQIEVTFDID
Sbjct: 422 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDID 481

Query: 484 ANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNA 543
           ANGILNVTATDKSTGK NKITITNDKGRLSKEEIERMV +AEKYKAEDEVQRE+++AKNA
Sbjct: 482 ANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNA 541

Query: 544 LESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKELEQ 603
           LESYAFNMKS V DEGLKGKISE+DK K+LDKC E++SWL+ N LAEKDEF+HKRKELEQ
Sbjct: 542 LESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQ 601

Query: 604 MCNPIITKLYQG-GCTGP-ACGTGYVPGRPATGPTIEEVD 641
           +CNPII+ LYQG G  GP   G     G   +GPTIEEVD
Sbjct: 602 VCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641


>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
          Length = 641

 Score = 1130 bits (2922), Expect = 0.0
 Identities = 573/640 (89%), Positives = 606/640 (94%), Gaps = 2/640 (0%)

Query: 4   AKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 63
           AK  AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA+
Sbjct: 2   AKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAL 61

Query: 64  NPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISS 123
           NPQNTVFDAKRLIGRKF DPVVQ+DMK WPFQVIN+G KPKV VSYKGE KAFYPEEISS
Sbjct: 62  NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISS 121

Query: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183
           MVLTK+KE AEA+LG+PVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI
Sbjct: 122 MVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 181

Query: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243
           AYGLD+ G+GER+VLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV+HF
Sbjct: 182 AYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHF 241

Query: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRAR 303
           VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQA+LEIDSL+EGIDFYTSITRAR
Sbjct: 242 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRAR 301

Query: 304 FEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNK 363
           FEELC+DLFR TLEPVEKALRDAK+DKA+IHD+VLVGGSTRIPKVQ+LLQD+FNGRDLNK
Sbjct: 302 FEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNK 361

Query: 364 SINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 423
           SINPDEAVAYGAAVQAAILMGDKSE VQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP
Sbjct: 362 SINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 421

Query: 424 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTFDID 483
           TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRF+L+GIPPAPRGVPQIEVTFDID
Sbjct: 422 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDID 481

Query: 484 ANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNA 543
           ANGILNVTATDKSTGK NKITITNDKGRLSKEEIERMV +AEKYKAEDEVQRE+++AKNA
Sbjct: 482 ANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNA 541

Query: 544 LESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKELEQ 603
           LESYAFNMKS V DEGLKGKISE+DK K+LDKC E++SWL+ N LAEKDEF+HKRKELEQ
Sbjct: 542 LESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQ 601

Query: 604 MCNPIITKLYQG-GCTGP-ACGTGYVPGRPATGPTIEEVD 641
           +CNPII+ LYQG G  GP   G     G   +GPTIEEVD
Sbjct: 602 VCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641


>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
          Length = 646

 Score = 1067 bits (2759), Expect = 0.0
 Identities = 534/645 (82%), Positives = 593/645 (91%), Gaps = 7/645 (1%)

Query: 4   AKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 63
           +KG A+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM
Sbjct: 2   SKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 61

Query: 64  NPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISS 123
           NP NTVFDAKRLIGR+F+D VVQ+DMK WPF V+N+ G+PKV V YKGE K+FYPEE+SS
Sbjct: 62  NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121

Query: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183
           MVLTK+KE AEA+LG  VTNAV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAAI
Sbjct: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181

Query: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243
           AYGLDK    ER+VLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+V+HF
Sbjct: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241

Query: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRAR 303
           + EFKRKHKKDIS+NKRAVRRLRTACERAKRTLSSSTQA++EIDSLYEGIDFYTSITRAR
Sbjct: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRAR 301

Query: 304 FEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNK 363
           FEEL ADLFRGTL+PVEKALRDAK+DK++IHDIVLVGGSTRIPK+Q+LLQD+FNG++LNK
Sbjct: 302 FEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNK 361

Query: 364 SINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 423
           SINPDEAVAYGAAVQAAIL GDKSE VQDLLLLDV PLSLG+ETAGGVMT LIKRN+TIP
Sbjct: 362 SINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIP 421

Query: 424 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTFDID 483
           TKQTQ FTTYSDNQPGVLIQVYEGERAMTKDNNLLG+F+LTGIPPAPRGVPQIEVTFDID
Sbjct: 422 TKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDID 481

Query: 484 ANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNA 543
           ANGILNV+A DKSTGK NKITITNDKGRLSKE+IERMV +AEKYKAEDE QR+K+++KN+
Sbjct: 482 ANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNS 541

Query: 544 LESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKELEQ 603
           LESYAFNMK+ V DE L+GKI++ DK KILDKCNE+++WL+ NQ AEK+EF+H++KELE+
Sbjct: 542 LESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEK 601

Query: 604 MCNPIITKLYQ------GGCTGPACGTGYVP-GRPATGPTIEEVD 641
           +CNPIITKLYQ      GG  G   G G  P G  ++GPTIEEVD
Sbjct: 602 VCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646


>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
          Length = 639

 Score = 1050 bits (2714), Expect = 0.0
 Identities = 526/641 (82%), Positives = 583/641 (90%), Gaps = 5/641 (0%)

Query: 3   TAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 62
           +A+G AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 2   SARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 61

Query: 63  MNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEIS 122
           MNP NT+FDAKRLIGRKF D  VQ+DMK WPF+V++EGGKPKV V YKGE K F+PEEIS
Sbjct: 62  MNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEIS 121

Query: 123 SMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 182
           SMVLTK+KE AEA+LG  V +AVITVPAYFNDSQRQATKDAG I GLNVLRIINEPTAAA
Sbjct: 122 SMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAA 181

Query: 183 IAYGLDKGG--QGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 240
           IAYGLDK G   GE++VLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+V
Sbjct: 182 IAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMV 241

Query: 241 SHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSIT 300
           SH  EEFKRKHKKDI  NKRAVRRLRTACERAKRTLSSSTQA++EIDSLYEG+DFYTSIT
Sbjct: 242 SHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSIT 301

Query: 301 RARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRD 360
           RARFEEL ADLFRGTLEPVEKALRDAK+DK +I +IVLVGGSTRIPK+Q+LLQD+FNG++
Sbjct: 302 RARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKE 361

Query: 361 LNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNS 420
           LNKSINPDEAVAYGAAVQAAIL+GDKSE VQDLLLLDV PLSLG+ETAGGVMT LIKRN+
Sbjct: 362 LNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNT 421

Query: 421 TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTF 480
           TIPTKQTQ FTTYSDNQ  VL+QVYEGERAMTKDNNLLG+FDLTGIPPAPRGVPQIEVTF
Sbjct: 422 TIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTF 481

Query: 481 DIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAA 540
           DIDANGILNVTA DKSTGK NKITITNDKGRLSK++I+RMV +AE+YK+EDE  R+++AA
Sbjct: 482 DIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAA 541

Query: 541 KNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKE 600
           KNALESY +N+K  V DE L+GKISE DKNKILDKC E+++WL+ NQ+AEKDE++HK+KE
Sbjct: 542 KNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKE 601

Query: 601 LEQMCNPIITKLYQGGCTGPACGTGYVPGRPATGPTIEEVD 641
           LE++CNPII+KLYQG   GP  G+G      + GPTIEEVD
Sbjct: 602 LERVCNPIISKLYQG---GPGGGSGGGGSGASGGPTIEEVD 639


>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
          Length = 643

 Score = 1039 bits (2687), Expect = 0.0
 Identities = 511/643 (79%), Positives = 585/643 (90%), Gaps = 2/643 (0%)

Query: 1   MATAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ 60
           M   + +A+GIDLGTTYSCVGVFQ G+VEI+ANDQGNRTTPSYVAFTDTERL+GDAAK+Q
Sbjct: 1   MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQ 60

Query: 61  VAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEE 120
            A+NP NTVFDAKRLIGRKF D  VQ+DMK WPF+V++EGGKPKV V Y+GE+K FYPEE
Sbjct: 61  AALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEE 120

Query: 121 ISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTA 180
           ISSMVL+K+KETAEA+LG PV +AVITVPAYFNDSQRQATKDAG IAGLNVLRIINEPTA
Sbjct: 121 ISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTA 180

Query: 181 AAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 240
           AAIAYGLD+ G GER+VLIFDLGGGTFDVS+L+ID G+FEVKATAGDTHLGGEDFDNRLV
Sbjct: 181 AAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLV 240

Query: 241 SHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSIT 300
           +HF+EEF+RKH KD+S NKRA+RRLRTACERAKRTLSSSTQA LEIDSL+EG+DFYTSIT
Sbjct: 241 NHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSIT 300

Query: 301 RARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRD 360
           RARFEELC+DLFR TLEPVEKALRDAK+DKA+IHD+VLVGGSTRIPKVQ+LLQD+FNG++
Sbjct: 301 RARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKE 360

Query: 361 LNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNS 420
           LNKSINPDEAVAYGAAVQAA+LMGDK EKVQDLLLLDVAPLSLGLETAGGVMT LI+RN+
Sbjct: 361 LNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNA 420

Query: 421 TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTF 480
           TIPTKQTQ FTTYSDNQPGV IQVYEGERAMTKDNNLLGRF+L+GIPPAPRGVPQIEVTF
Sbjct: 421 TIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF 480

Query: 481 DIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAA 540
           DIDANGIL+VTATD+STGK NKITITNDKGRLSKEE+ERMV +AE+YKAEDE QR+++AA
Sbjct: 481 DIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAA 540

Query: 541 KNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKE 600
           KN+LE++ F++K  + +E L+ KI E D+ K+ DKC E+L+WLE NQLAEK+E++H+++E
Sbjct: 541 KNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRE 600

Query: 601 LEQMCNPIITKLYQGGCT--GPACGTGYVPGRPATGPTIEEVD 641
           LEQ+C PI ++LY G     G +CGT    G P+TGP IEEVD
Sbjct: 601 LEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD 643


>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
          Length = 493

 Score =  815 bits (2104), Expect = 0.0
 Identities = 407/472 (86%), Positives = 443/472 (93%), Gaps = 1/472 (0%)

Query: 4   AKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 63
           +KG A+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM
Sbjct: 2   SKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 61

Query: 64  NPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISS 123
           NP NTVFDAKRLIGR+F+D VVQ+DMK WPF V+N+ G+PKV V YKGE K+FYPEE+SS
Sbjct: 62  NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121

Query: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183
           MVLTK+KE AEA+LG  VTNAV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAAI
Sbjct: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181

Query: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243
           AYGLDK    ER+VLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+V+HF
Sbjct: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241

Query: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRAR 303
           + EFKRKHKKDIS+NKRAVRRLRTACERAKRTLSSSTQA++EIDSLYEGIDFYTSITRAR
Sbjct: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRAR 301

Query: 304 FEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNK 363
           FEEL ADLFRGTL+PVEKALRDAK+DK++IHDIVLVGGSTRIPK+Q+LLQD+FNG++LNK
Sbjct: 302 FEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNK 361

Query: 364 SINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 423
           SINPDEAVAYGAAVQAAIL GDKSE VQDLLLLDV PLSLG+ETAGGVMT LIKRN+TIP
Sbjct: 362 SINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIP 421

Query: 424 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPA-PRGVP 474
           TKQTQ FTTYSDNQPGVLIQVYEGERAMTKDNNLLG+F+LTG+P   P G P
Sbjct: 422 TKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473


>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
          Length = 654

 Score =  782 bits (2019), Expect = 0.0
 Identities = 398/618 (64%), Positives = 498/618 (80%), Gaps = 8/618 (1%)

Query: 6   GIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMN 64
           G  +GIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  N
Sbjct: 28  GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87

Query: 65  PQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKG-ENKAFYPEEISS 123
           P+NTVFDAKRLIGR +NDP VQ D+K  PF+V+ +  KP + V   G + K F PEEIS+
Sbjct: 88  PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147

Query: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183
           MVLTK+KETAEA+LG  VT+AV+TVPAYFND+QRQATKDAG IAGLNV+RIINEPTAAAI
Sbjct: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207

Query: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243
           AYGLDK  +GE+++L+FDLGGGTFDVS+LTID+G+FEV AT GDTHLGGEDFD R++ HF
Sbjct: 208 AYGLDKR-EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 266

Query: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRAR 303
           ++ +K+K  KD+ ++ RAV++LR   E+AKR LSS  QA +EI+S YEG DF  ++TRA+
Sbjct: 267 IKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAK 326

Query: 304 FEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNK 363
           FEEL  DLFR T++PV+K L D+ + K+ I +IVLVGGSTRIPK+Q+L++++FNG++ ++
Sbjct: 327 FEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSR 386

Query: 364 SINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 423
            INPDEAVAYGAAVQA +L GD  +   DL+LLDV PL+LG+ET GGVMT LI RN+ +P
Sbjct: 387 GINPDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 444

Query: 424 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTFDID 483
           TK++QIF+T SDNQP V I+VYEGER +TKDN+LLG FDLTGIPPAPRGVPQIEVTF+ID
Sbjct: 445 TKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID 504

Query: 484 ANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNA 543
            NGIL VTA DK TG  NKITITND+ RL+ EEIERMV DAEK+  ED+  +E+I  +N 
Sbjct: 505 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE 564

Query: 544 LESYAFNMKSVVSD-EGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKELE 602
           LESYA+++K+ + D E L GK+S  DK  +     E + WLE +Q A+ ++F  K+KELE
Sbjct: 565 LESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELE 624

Query: 603 QMCNPIITKLYQGGCTGP 620
           ++  PII+KLY  G  GP
Sbjct: 625 EIVQPIISKLY--GSAGP 640


>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
          Length = 679

 Score =  562 bits (1449), Expect = e-160
 Identities = 305/585 (52%), Positives = 408/585 (69%), Gaps = 21/585 (3%)

Query: 5   KGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 63
           KG  +GIDLGTT SCV V +  + +++ N +G RTTPS VAFT D ERL+G  AK Q   
Sbjct: 52  KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111

Query: 64  NPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISS 123
           NP NT +  KRLIGR+++DP VQ D+K  PF+++        + ++    K + P +I +
Sbjct: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAH---GKLYSPSQIGA 168

Query: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183
            VL K+KETAE +LGH   NAVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+
Sbjct: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228

Query: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243
           AYGLDK    ++ + ++DLGGGTFD+SIL I  G+FEVK+T GDT LGGEDFD  L+ H 
Sbjct: 229 AYGLDKSE--DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286

Query: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGID----FYTSI 299
           V+EFKR+   D++++  A++R+R A E+AK  LSSS Q ++ +  L             +
Sbjct: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346

Query: 300 TRARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGR 359
           TRA+FE +  DL R T+ P +KA++DA++ K+ I +++LVGG TR+PKVQ+ +QD F GR
Sbjct: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GR 405

Query: 360 DLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRN 419
             +K++NPDEAVA GAA+Q  +L GD    V D+LLLDV PLSLG+ET GGV T LI RN
Sbjct: 406 APSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRN 461

Query: 420 STIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVT 479
           +TIPTK++Q+F+T +D Q  V I+V +GER M  DN LLG+F L GIPPAPRGVPQIEVT
Sbjct: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVT 521

Query: 480 FDIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIA 539
           FDIDANGI++V+A DK TG+  +I I    G LSK++IE MV +AEKY  ED  ++E++ 
Sbjct: 522 FDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKERVE 580

Query: 540 AKNALESYAFNMKSVVSDEGLKGKISESDKNKI---LDKCNELLS 581
           A N  E    + ++ +  E  K ++   + NK+   + K  ELL+
Sbjct: 581 AVNMAEGIIHDTETKM--EEFKDQLPADECNKLKEEISKMRELLA 623


>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
          Length = 509

 Score =  314 bits (804), Expect = 2e-85
 Identities = 177/504 (35%), Positives = 287/504 (56%), Gaps = 7/504 (1%)

Query: 8   AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQN 67
           AIG+ LG T +CV V++ G+  ++AND G+R TP+ VA+++ E ++G AAK     N  N
Sbjct: 3   AIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNISN 62

Query: 68  TVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISSMVLT 127
           TV   K+++GR  +DP  Q  +      VI + GK +  +    E K   PE+++ ++ +
Sbjct: 63  TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIFS 122

Query: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187
           K+KETA + LG    + VITVP  F + Q+ A  +A   AG NVLR+I+EP+AA +AYG+
Sbjct: 123 KMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGI 182

Query: 188 DKGGQ-GERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEE 246
            +    G+ ++L+F LGG +  +S++ ++ GI+ V +T  D ++GG  F   L  +   E
Sbjct: 183 GQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLASE 242

Query: 247 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEE 306
           F+R  K D+  N RA+ +L  + E AK +LS+   AN  +DSLYEG DF  +++RARFE 
Sbjct: 243 FQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFEL 302

Query: 307 LCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNKSIN 366
           LC+ LF   +E +   L         I+ +VL GGS+RIPK+Q+L++D F   +L  SI 
Sbjct: 303 LCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSIP 362

Query: 367 PDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAP---LSLGLETAGGV-MTALIKRNSTI 422
           PDE +  GAA++A IL+G ++  V+D L+++ +    L  G++ +G    T L    + +
Sbjct: 363 PDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTPL 422

Query: 423 PTKQTQIFTTYSDNQPGVLIQVYEGE-RAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTFD 481
           P ++         +   V +++YE + +   K+     +  L  +     G+  I     
Sbjct: 423 PARRQHTLQA-PGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVLT 481

Query: 482 IDANGILNVTATDKSTGKVNKITI 505
           +  +G L+VT TD+ TGK   I+I
Sbjct: 482 MKRDGSLHVTCTDQETGKCEAISI 505


>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
          Length = 840

 Score =  293 bits (749), Expect = 4e-79
 Identities = 189/580 (32%), Positives = 312/580 (53%), Gaps = 27/580 (4%)

Query: 9   IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNT 68
           +GIDLG     V V + G +E IAN+  +R TP+ ++F    R IG AAK+QV  N +NT
Sbjct: 4   VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63

Query: 69  VFDAKRLIGRKFNDPVVQADMKLWPFQVIN-EGGKPKVLVSYKGENKAFYPEEISSMVLT 127
           V   KR  GR F+DP V+A+     + ++    G   + V+Y  E + F  E++++M+L+
Sbjct: 64  VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123

Query: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187
           KLKETAE+ L  PV + V++VP ++ D++R++  DA  IAGLN LR++NE TA A+AYG+
Sbjct: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183

Query: 188 DKGG-----QGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSH 242
            K       +  R+V+  D+G   + VS+   + G  +V ATA DT LGG  FD  LV+H
Sbjct: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243

Query: 243 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQANLEIDSLYEGIDFYTSITR 301
           F EEF +K+K DI    RA+ RL   CE+ K+ +S +++   L I+     +D   ++ R
Sbjct: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303

Query: 302 ARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDL 361
            +F E+C DL      P+   L   K+ K  I+ + +VGG+TRIP V+  +  +F G++L
Sbjct: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362

Query: 362 NKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLE-----TAGGVMTALI 416
           + ++N DEAV  G A+Q AIL    + KV++  + DV P  + L        G     + 
Sbjct: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420

Query: 417 KRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRG-VPQ 475
            +N   P  +     T+   +P  L   Y   + +   +  + +F +  + P   G   +
Sbjct: 421 SKNHAAPFSKV---LTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477

Query: 476 IEVTFDIDANGILNVTA---TDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDE 532
           ++V   ++ +GI +V++    +    + N+  +  D+   +KEE E+M +D E+   E+ 
Sbjct: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEE-EKMQVDQEEPHVEE- 533

Query: 533 VQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKNKI 572
            Q+++  A+N  ES         S +    +  ++ K K+
Sbjct: 534 -QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 28/99 (28%), Positives = 52/99 (52%), Gaps = 2/99 (2%)

Query: 511 RLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKN 570
           ++ +E +   + +  K   +D++++E+  AKNA+E Y + M+  +S E  K  +SE D+N
Sbjct: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEK-FVSEDDRN 646

Query: 571 KILDKCNELLSWL-EVNQLAEKDEFDHKRKELEQMCNPI 608
               K  +  +WL E  +   K  +  K  EL+ +  PI
Sbjct: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 22/100 (22%), Positives = 43/100 (43%), Gaps = 14/100 (14%)

Query: 526 KYKAEDEVQREKIAAK--NALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSW- 582
           K + ++  +R K+  +    ++ Y   + S  + E     +  +D  K+    NE + W 
Sbjct: 686 KIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWM 745

Query: 583 -----------LEVNQLAEKDEFDHKRKELEQMCNPIITK 611
                      L ++ + +  E + K KEL   C+PII+K
Sbjct: 746 NNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISK 785


>gi|48928056 heat shock protein 70kDa family member 13 precursor
           [Homo sapiens]
          Length = 471

 Score =  279 bits (714), Expect = 5e-75
 Identities = 166/418 (39%), Positives = 243/418 (58%), Gaps = 50/418 (11%)

Query: 9   IGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQ 66
           IGIDLGTTY  VGVF    GKV++I ++ G+ + PS V+FTD +  +G  +      NPQ
Sbjct: 34  IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93

Query: 67  NTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISSMVL 126
           NT++DAKR IG+ F    ++A++  +PF+V+N+ G  +  V+   E     PE + S +L
Sbjct: 94  NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLL 152

Query: 127 TKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYG 186
            KLKE AEA+LG PV NAVI+VPA F+  QR +T +A  +AGL +LR+INEPTAAA+AYG
Sbjct: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212

Query: 187 LDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEE 246
           L K      HVL+ DLGGGT DVS+L    G+F  +A +G+  LGG+DF+ RL+ +  ++
Sbjct: 213 LHKA--DVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270

Query: 247 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEI-------------------- 286
             + +   +   K  + RLR A E  K  L+    A L +                    
Sbjct: 271 IYQTY-GFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329

Query: 287 -DSLYEGID----------------------FYTSITRARFEELCADLFRGTLEPVEKAL 323
            D L    D                      F T I+R  F+ L  DLF+  L P+++ L
Sbjct: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389

Query: 324 RDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNKSINPDEAVAYGAAVQAAI 381
           ++  ++K +I ++VLVGGSTRIP++++++Q++F G+D N S++PD AV  G A+QA I
Sbjct: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGI 446


>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
          Length = 839

 Score =  278 bits (712), Expect = 8e-75
 Identities = 182/604 (30%), Positives = 310/604 (51%), Gaps = 48/604 (7%)

Query: 9   IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNT 68
           +GIDLG     + V + G +E IAN+  +R TP+ ++     R IG+AAK+Q+  N +NT
Sbjct: 4   VGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNT 63

Query: 69  VFDAKRLIGRKFNDPVVQADMKLWPFQVIN-EGGKPKVLVSYKGENKAFYPEEISSMVLT 127
           +   K+L GR F+DP+VQ +    P+++     G   V V Y  E + F  E+++ M+L 
Sbjct: 64  IHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLA 123

Query: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187
           KLKET+E  L  PV + VI++P++F D++R++   A  +AGLN LR++NE TA A+AYG+
Sbjct: 124 KLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGI 183

Query: 188 DKG-----GQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSH 242
            K       +  R+V+  D+G   + V +   + G  +V AT  D +LGG +FD  LV +
Sbjct: 184 YKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEALVDY 243

Query: 243 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQANLEIDSLYEGIDFYTSITR 301
           F +EFK K+K ++ +N RA+ RL   CE+ K+ +S +++   L I+     +D  + + R
Sbjct: 244 FCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNR 303

Query: 302 ARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDL 361
           A+FE+LCA L      P++  +  A + +  I  I +VGG+TRIP V+  +  +F  +D+
Sbjct: 304 AQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFL-KDI 362

Query: 362 NKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGL------ETAGGVMTAL 415
           + ++N DEAVA G A+Q AIL    + KV++  + D+ P S+ L      E   G     
Sbjct: 363 STTLNADEAVARGCALQCAIL--SPAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVF 420

Query: 416 IKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRG-VP 474
            K +   P   +++  T+   +P  L   Y     +   +  +G F +  + P   G   
Sbjct: 421 CKNH---PAPFSKVI-TFHKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDSS 476

Query: 475 QIEVTFDIDANGILNVTATDKSTGKVNKITITNDKG-----------RLSKEEIERMVLD 523
           +++V   ++ +GI +V     S   + K  +  D               +K+ +++M +D
Sbjct: 477 KVKVKVRVNIHGIFSVA----SASVIEKQNLEGDHSDAPMETETSFKNENKDNMDKMQVD 532

Query: 524 AE--------KYKAEDEVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKNKILDK 575
            E        ++  E+E+       K+A+      +   +     KGK+   D       
Sbjct: 533 QEEGHQKCHAEHTPEEEIDHTGAKTKSAVSDKQDRLNQTLK----KGKVKSIDLPIQSSL 588

Query: 576 CNEL 579
           C +L
Sbjct: 589 CRQL 592



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 28/118 (23%), Positives = 56/118 (47%), Gaps = 5/118 (4%)

Query: 498 GKVNKITITNDKG---RLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSV 554
           GKV  I +        +L ++ +   + +  K   +D++++E+  AKNA+E Y ++ +  
Sbjct: 575 GKVKSIDLPIQSSLCRQLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDR 634

Query: 555 VSDEGLKGKISESDKNKILDKCNELLSWL-EVNQLAEKDEFDHKRKELEQMCNPIITK 611
           +     K  I+  D +K+     +  +WL E  +   K  +  K +EL++   PI  K
Sbjct: 635 LGTVYEK-FITPEDLSKLSAVLEDTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMK 691


>gi|42544159 heat shock 105kD [Homo sapiens]
          Length = 858

 Score =  274 bits (701), Expect = 2e-73
 Identities = 187/578 (32%), Positives = 297/578 (51%), Gaps = 26/578 (4%)

Query: 9   IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNT 68
           +G+D+G+    + V + G +E IAN+  +R TPS ++F    R IG AAKNQ   +  NT
Sbjct: 4   VGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNT 63

Query: 69  VFDAKRLIGRKFNDPVVQADMKLWPFQVIN-EGGKPKVLVSYKGENKAFYPEEISSMVLT 127
           V + KR  GR FNDP +Q + +   + ++  + G   + V Y GE   F  E+I++M+LT
Sbjct: 64  VSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLT 123

Query: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187
           KLKETAE  L  PVT+ VI+VP++F D++R++  DA  I GLN LR++N+ TA A+ YG+
Sbjct: 124 KLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGI 183

Query: 188 DKG-----GQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSH 242
            K       +  R V+  D+G   F VS    + G  +V  TA D  LGG++FD +LV H
Sbjct: 184 YKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEH 243

Query: 243 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSS-STQANLEIDSLYEGIDFYTSITR 301
           F  EFK K+K D     RA+ RL   CE+ K+ +SS ST   L I+      D    + R
Sbjct: 244 FCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNR 303

Query: 302 ARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDL 361
           ++FEELCA+L +    P+   L    +    +  + +VGG+TRIP V+  +  +F G+D+
Sbjct: 304 SQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-GKDI 362

Query: 362 NKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGL------ETAGGVMTAL 415
           + ++N DEAVA G A+Q AIL    + KV++  + D  P  + L      E   GV   +
Sbjct: 363 STTLNADEAVARGCALQCAIL--SPAFKVREFSVTDAVPFPISLIWNHDSEDTEGV-HEV 419

Query: 416 IKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRG-VP 474
             RN   P  +     T+    P  L   Y   + +      +GRF +  +     G   
Sbjct: 420 FSRNHAAPFSKV---LTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKS 476

Query: 475 QIEVTFDIDANGILNVTA---TDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAED 531
           +++V   ++ +GI  ++     +K   + N+++   D   L++   E    D    +   
Sbjct: 477 RVKVKVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNS 536

Query: 532 EVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDK 569
           E   +     +A ++        ++ E  + KI ++DK
Sbjct: 537 EAGTQPQVQTDAQQTSQSPPSPELTSE--ENKIPDADK 572



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 2/99 (2%)

Query: 511 RLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKN 570
           +L K+ +   +    K   +D++++E+  AKNA+E Y +  +  +     K  I E D  
Sbjct: 605 QLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEK-FICEQDHQ 663

Query: 571 KILDKCNELLSWL-EVNQLAEKDEFDHKRKELEQMCNPI 608
             L    E   WL E  +   K  +  K +EL ++  P+
Sbjct: 664 NFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPV 702



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 12/60 (20%)

Query: 564 ISESDKNKILDKCNELLSWLE--VNQLAEKD----------EFDHKRKELEQMCNPIITK 611
           I ES+  K+    NE++ W+   +N  A+K           E   K KEL   C P++T+
Sbjct: 743 IDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVTQ 802


>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  219 bits (559), Expect = 5e-57
 Identities = 143/455 (31%), Positives = 235/455 (51%), Gaps = 31/455 (6%)

Query: 9   IGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQN 67
           + +DLG+    V + + G  +EI+ N +  R TP  V   + ER  GD+A +    NP+ 
Sbjct: 36  MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95

Query: 68  TVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISSMVLT 127
           T+   + L+G++ ++P V      +P   +    + + +         F PEE+  MVL 
Sbjct: 96  TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLN 155

Query: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187
             +  AE F   P+ +AVITVP +FN ++R+A   A  +AGL VL++IN+ TA A++YG+
Sbjct: 156 YSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGV 215

Query: 188 DKG---GQGERHVLIFDLGGGTFDVSILTI------DDGI---FEVKATAGDTHLGGEDF 235
            +        ++++ +D+G G+   +I+T       + G+    +++    D  LGG + 
Sbjct: 216 FRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEM 275

Query: 236 D----NRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYE 291
           +     RL   F E+ K +  KD+ +N RA+ +L     R K  LS++     +I+ L +
Sbjct: 276 ELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMD 335

Query: 292 GIDFYTSITRARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRL 351
            +DF   +TR  FEELCADLF     PV++AL+ A+M   +I  ++LVGG+TR+P+VQ +
Sbjct: 336 DVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEV 395

Query: 352 LQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLD--VAPLSL------ 403
           L       +L K+IN DEA A GA  QAA L   K+ KV+  ++ D  V P+ +      
Sbjct: 396 LLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFTREV 453

Query: 404 ----GLETAGGVMTALIKRNSTIPTKQTQIFTTYS 434
               G+ +       L  R    P ++   F  YS
Sbjct: 454 EEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYS 488


>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  219 bits (559), Expect = 5e-57
 Identities = 143/455 (31%), Positives = 235/455 (51%), Gaps = 31/455 (6%)

Query: 9   IGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQN 67
           + +DLG+    V + + G  +EI+ N +  R TP  V   + ER  GD+A +    NP+ 
Sbjct: 36  MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95

Query: 68  TVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISSMVLT 127
           T+   + L+G++ ++P V      +P   +    + + +         F PEE+  MVL 
Sbjct: 96  TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLN 155

Query: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187
             +  AE F   P+ +AVITVP +FN ++R+A   A  +AGL VL++IN+ TA A++YG+
Sbjct: 156 YSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGV 215

Query: 188 DKG---GQGERHVLIFDLGGGTFDVSILTI------DDGI---FEVKATAGDTHLGGEDF 235
            +        ++++ +D+G G+   +I+T       + G+    +++    D  LGG + 
Sbjct: 216 FRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEM 275

Query: 236 D----NRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYE 291
           +     RL   F E+ K +  KD+ +N RA+ +L     R K  LS++     +I+ L +
Sbjct: 276 ELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMD 335

Query: 292 GIDFYTSITRARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRL 351
            +DF   +TR  FEELCADLF     PV++AL+ A+M   +I  ++LVGG+TR+P+VQ +
Sbjct: 336 DVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEV 395

Query: 352 LQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLD--VAPLSL------ 403
           L       +L K+IN DEA A GA  QAA L   K+ KV+  ++ D  V P+ +      
Sbjct: 396 LLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFTREV 453

Query: 404 ----GLETAGGVMTALIKRNSTIPTKQTQIFTTYS 434
               G+ +       L  R    P ++   F  YS
Sbjct: 454 EEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYS 488


>gi|38348298 ankyrin repeat domain 45 [Homo sapiens]
          Length = 266

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 1/74 (1%)

Query: 540 AKNALESYAFNMKSVVSD-EGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKR 598
           A+  L+ Y   +   V+D E   GK+ + DKN IL  C     WLE +  A  +E   +R
Sbjct: 167 ARLTLKKYIAKVSLAVTDTEKGSGKLLKEDKNTILSACRAKNEWLETHTEASINELFEQR 226

Query: 599 KELEQMCNPIITKL 612
           ++LE +  PI TK+
Sbjct: 227 QQLEDIVTPIFTKM 240


>gi|9910266 kinesin family member 15 [Homo sapiens]
          Length = 1388

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 64/345 (18%), Positives = 147/345 (42%), Gaps = 29/345 (8%)

Query: 275  TLSSSTQANLEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKALRDAKMDKAKIH 334
            +L +   + L+ D L E +     +    FE +  +L   T++    AL+ AK+D+ +  
Sbjct: 685  SLYTQNSSILDNDILNEPVP--PEMNEQAFEAISEEL--RTVQEQMSALQ-AKLDEEEHK 739

Query: 335  DIVLVGGSTRIPKVQRLLQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLL 394
            ++ L     ++      +Q+ F+   ++ +   +E ++    ++  +    +++   D L
Sbjct: 740  NLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQL---QETQTKNDFL 796

Query: 395  LLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQV----YEGERA 450
              +V  L + L +A   ++++    S+  T Q + F   S+    V +Q+     E E+ 
Sbjct: 797  KSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKL 856

Query: 451  MTKD-------NNL--LGRFDLTGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKVN 501
            +          +NL  + +F++  +    +   +   T   D N ++ +   +K      
Sbjct: 857  LESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKL 916

Query: 502  KITITNDKGRLSKEEIERMVLDAEKYKAEDEVQR--EKIAAKNALESYAFNMKSVVSDEG 559
             +    DK   SKE ++  VL+A + + + E  +  +++A    LE      + V+S   
Sbjct: 917  SLQFEEDKENSSKEILK--VLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISS-- 972

Query: 560  LKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKELEQM 604
               K  +SDK  + D  N++   L  +   + +  D  ++EL+ +
Sbjct: 973  -LEKSRDSDKKVVADLMNQIQE-LRTSVCEKTETIDTLKQELKDI 1015


>gi|123317881 germ cell associated 1 isoform 4 [Homo sapiens]
          Length = 362

 Score = 37.0 bits (84), Expect = 0.056
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 15/94 (15%)

Query: 241 SHFVEEFKRKHKKDISQNKRAV--------RRLRTACERAKRTLSSSTQANLEIDSLYEG 292
           +  V EFK KH K   +N   +        RRL +A        S     N  I S+ EG
Sbjct: 270 TRMVLEFKCKHSKSFKENPNCLPHHHQCFPRRLSSAAPTVGPLTSYHQYHNQPIHSVSEG 329

Query: 293 IDFYTSITRARFEELCADLFRGTLEPVEKALRDA 326
           +DFY+ +    F+       RG  + +++A+R +
Sbjct: 330 VDFYSELRNKGFQ-------RGASQELKEAVRSS 356


>gi|123317861 germ cell associated 1 isoform 2 [Homo sapiens]
          Length = 326

 Score = 37.0 bits (84), Expect = 0.056
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 15/94 (15%)

Query: 241 SHFVEEFKRKHKKDISQNKRAV--------RRLRTACERAKRTLSSSTQANLEIDSLYEG 292
           +  V EFK KH K   +N   +        RRL +A        S     N  I S+ EG
Sbjct: 234 TRMVLEFKCKHSKSFKENPNCLPHHHQCFPRRLSSAAPTVGPLTSYHQYHNQPIHSVSEG 293

Query: 293 IDFYTSITRARFEELCADLFRGTLEPVEKALRDA 326
           +DFY+ +    F+       RG  + +++A+R +
Sbjct: 294 VDFYSELRNKGFQ-------RGASQELKEAVRSS 320


>gi|31317303 heat shock 70kD protein 12B [Homo sapiens]
          Length = 686

 Score = 36.2 bits (82), Expect = 0.096
 Identities = 55/225 (24%), Positives = 86/225 (38%), Gaps = 42/225 (18%)

Query: 193 GERHVLIFDLGGGTFDVSILTIDD--GIFE--VKATAGDTHLGGED--FDNRLVSHFVEE 246
           G+R+V + D GGGT D+++  ++   G  +   KA+ G     G D  F+  L   F E+
Sbjct: 313 GDRYV-VADCGGGTVDLTVHQLEQPHGTLKELYKASGGPYGAVGVDLAFEQLLCRIFGED 371

Query: 247 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFY---------T 297
           F    K+   Q   A   L  A E  KRT        L I   +  IDFY         T
Sbjct: 372 FIATFKR---QRPAAWVDLTIAFEARKRTAGPHRAGALNISLPFSFIDFYRKQRGHNVET 428

Query: 298 SITRA------------------RFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLV 339
           ++ R+                     EL      G ++ +E  L   ++   K+  + LV
Sbjct: 429 ALRRSSVNFVKWSSQGMLRMSCEAMNELFQPTVSGIIQHIEALLARPEVQGVKL--LFLV 486

Query: 340 GGSTRIPKVQRLLQDYFNGRDLNKSINPDEAVAYGAAVQAAILMG 384
           GG      +Q  +Q     R L   +  D  +     ++ A+L G
Sbjct: 487 GGFAESAVLQHAVQAALGARGLRVVVPHDVGL---TILKGAVLFG 528


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 34/135 (25%), Positives = 65/135 (48%), Gaps = 12/135 (8%)

Query: 471  RGVPQIEVTFDIDANGILNVTATDKSTGKVN-----KITITNDKGRLSKEEIERMVLDAE 525
            RG+ ++ V  + D    L++    K   + N     K+     + ++S+E  E ++LDAE
Sbjct: 2119 RGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAE 2178

Query: 526  KYKAEDEVQREKI-AAKNALESYAFNMKSVVSD-EGLKGKISE-----SDKNKILDKCNE 578
              KAE E  + +I     +L+ +  ++ ++ S+ E L  +I E     S+ +K+L     
Sbjct: 2179 NSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKS 2238

Query: 579  LLSWLEVNQLAEKDE 593
            LL   E  ++  K+E
Sbjct: 2239 LLEEKEQAEIQIKEE 2253


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 29/116 (25%), Positives = 54/116 (46%), Gaps = 25/116 (21%)

Query: 510  GRLSKEEIERMVLDAEKYKAEDEVQREKIAAK-----------NALESYAFNMKS----- 553
            G++SKEE++    + +  K E+E ++ K+ A            + LE    N+K      
Sbjct: 970  GQISKEELQH---EFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKE 1026

Query: 554  VVSDEGLKGKISESDKNK------ILDKCNELLSWLEVNQLAEKDEFDHKRKELEQ 603
            +   E  +G++ E  +NK      +  KC E+  +L+     ++ E  H RK+LE+
Sbjct: 1027 IPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEE 1082


>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
          Length = 2647

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 23/80 (28%), Positives = 31/80 (38%)

Query: 164  GVIAGLNVLRIINEPTAAAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKA 223
            G  AG      I+   A     GL   G  E  +   D G GT  VS +  + G + +  
Sbjct: 1079 GGSAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINI 1138

Query: 224  TAGDTHLGGEDFDNRLVSHF 243
               DTH+ G  F   +V  F
Sbjct: 1139 LFADTHIPGSPFKAHVVPCF 1158


>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
          Length = 2639

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 23/80 (28%), Positives = 31/80 (38%)

Query: 164  GVIAGLNVLRIINEPTAAAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKA 223
            G  AG      I+   A     GL   G  E  +   D G GT  VS +  + G + +  
Sbjct: 1079 GGSAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINI 1138

Query: 224  TAGDTHLGGEDFDNRLVSHF 243
               DTH+ G  F   +V  F
Sbjct: 1139 LFADTHIPGSPFKAHVVPCF 1158


>gi|210147558 hypothetical protein LOC202051 [Homo sapiens]
          Length = 205

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 25/93 (26%), Positives = 48/93 (51%), Gaps = 15/93 (16%)

Query: 512 LSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKNK 571
           L+KEE +      E      ++++EK+A + AL S    +KS V  E  K       K++
Sbjct: 74  LAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSS----VKSKVLQESSK-------KDQ 122

Query: 572 ILDKCNELLSWLEVNQLAEKDEFDHKRKELEQM 604
           ++ KCNE    +E + + ++D  + K  E++++
Sbjct: 123 LITKCNE----IESHIIKQEDILNGKENEIKEL 151


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 16/77 (20%), Positives = 37/77 (48%)

Query: 231 GGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLY 290
           G  D + + +   VE+FK+K++ +I++   A     T  +       +  +   ++D+L 
Sbjct: 270 GRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALI 329

Query: 291 EGIDFYTSITRARFEEL 307
           + IDF  ++  A   ++
Sbjct: 330 DEIDFLRTLYDAELSQM 346


>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
           sapiens]
          Length = 732

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 51/188 (27%), Positives = 78/188 (41%), Gaps = 17/188 (9%)

Query: 229 HLGGEDFDNRLVSHFVEEFKRKHKKDISQ-----NKRAVRRLRTACERAKRTLSSSTQAN 283
           ++ GE  D    S FVE   RKH  ++       ++  V++L+   E   +TL S T+  
Sbjct: 493 YITGETKDQVANSAFVERL-RKHGLEVIYMIEPIDEYCVQQLK---EFEGKTLVSVTKEG 548

Query: 284 LEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGST 343
           LE+    E         + +FE LC  +     + VEK +   ++  +    +    G T
Sbjct: 549 LELPEDEEEKKKQEE-KKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWT 607

Query: 344 ----RIPKVQRLLQDYFNGRDLNKS---INPDEAVAYGAAVQAAILMGDKSEKVQDLLLL 396
               RI K Q L  +   G    K    INPD ++      +A     DKS K   +LL 
Sbjct: 608 ANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLY 667

Query: 397 DVAPLSLG 404
           + A LS G
Sbjct: 668 ETALLSSG 675


>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
           sapiens]
          Length = 854

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 51/188 (27%), Positives = 78/188 (41%), Gaps = 17/188 (9%)

Query: 229 HLGGEDFDNRLVSHFVEEFKRKHKKDISQ-----NKRAVRRLRTACERAKRTLSSSTQAN 283
           ++ GE  D    S FVE   RKH  ++       ++  V++L+   E   +TL S T+  
Sbjct: 615 YITGETKDQVANSAFVERL-RKHGLEVIYMIEPIDEYCVQQLK---EFEGKTLVSVTKEG 670

Query: 284 LEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGST 343
           LE+    E         + +FE LC  +     + VEK +   ++  +    +    G T
Sbjct: 671 LELPEDEEEKKKQEE-KKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWT 729

Query: 344 ----RIPKVQRLLQDYFNGRDLNKS---INPDEAVAYGAAVQAAILMGDKSEKVQDLLLL 396
               RI K Q L  +   G    K    INPD ++      +A     DKS K   +LL 
Sbjct: 730 ANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLY 789

Query: 397 DVAPLSLG 404
           + A LS G
Sbjct: 790 ETALLSSG 797


>gi|102469034 janus kinase 1 [Homo sapiens]
          Length = 1154

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 30/127 (23%), Positives = 56/127 (44%), Gaps = 12/127 (9%)

Query: 499 KVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSVVSDE 558
           K N +++  +K +L ++++E       K+K ++E  + KI  +    SY   +  +V  E
Sbjct: 328 KPNVVSVEKEKNKLKRKKLEN------KHKKDEE--KNKIREEWNNFSYFPEITHIVIKE 379

Query: 559 GLKGKISESDKNKI---LDKCNELLSWLEVNQLAEKDEFDHKRKELEQMCNPIITKLYQG 615
            +   I++ D  K+   L    E LS++ +     +   D        +  P+I    Q 
Sbjct: 380 SVVS-INKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQN 438

Query: 616 GCTGPAC 622
           GC GP C
Sbjct: 439 GCHGPIC 445


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,495,245
Number of Sequences: 37866
Number of extensions: 975512
Number of successful extensions: 3185
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 3070
Number of HSP's gapped (non-prelim): 102
length of query: 641
length of database: 18,247,518
effective HSP length: 109
effective length of query: 532
effective length of database: 14,120,124
effective search space: 7511905968
effective search space used: 7511905968
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.