Guide to the Human Genome
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Name: JAK1 Sequence: fasta or formatted (1154aa) NCBI GI: 102469034
Description:

janus kinase 1

Referenced in:

Interferon
Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.3         50           2
 C cysteine            2.8         32           2
 D aspartate           5.6         65           2
 E glutamate           8.2         95           2
 F phenylalanine       3.8         44           2
 G glycine             4.9         57           2
 H histidine           2.9         34           2
 I isoleucine          5.7         66           1
 K lysine              9.0        104           3
 L leucine             9.7        112           3
 M methionine          2.9         34           2
 N asparagine          5.1         59           2
 P proline             4.5         52           2
 Q glutamine           3.6         41           2
 R arginine            4.9         57           1
 S serine              6.3         73           2
 T threonine           4.7         54           2
 V valine              5.6         65           2
 W tryptophan          1.3         15           1
 Y tyrosine            3.9         45           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   janus kinase 1 
TYK2                  0.412   tyrosine kinase 2 
JAK2                  0.377   Janus kinase 2 
JAK3                  0.316   Janus kinase 3 
FRK                   0.068   fyn-related kinase 
ERBB4                 0.066   v-erb-a erythroblastic leukemia viral oncogene homo...
ERBB4                 0.066   v-erb-a erythroblastic leukemia viral oncogene homolo...
FGFR4                 0.063   fibroblast growth factor receptor 4 isoform 2 precur...
FGFR4                 0.063   fibroblast growth factor receptor 4 isoform 1 precur...
FGFR4                 0.063   fibroblast growth factor receptor 4 isoform 1 precur...
TNK2                  0.063   tyrosine kinase, non-receptor, 2 isoform 1 
TNK2                  0.063   tyrosine kinase, non-receptor, 2 isoform 2 
FGFR1                 0.062   fibroblast growth factor receptor 1 isoform 4 precur...
FGFR1                 0.062   fibroblast growth factor receptor 1 isoform 3 precur...
FGFR1                 0.062   fibroblast growth factor receptor 1 isoform 2 precur...
FGFR1                 0.062   fibroblast growth factor receptor 1 isoform 1 precu...
ZAP70                 0.061   zeta-chain associated protein kinase 70kDa isoform 2...
ZAP70                 0.061   zeta-chain associated protein kinase 70kDa isoform 1...
NTRK3                 0.061   neurotrophic tyrosine kinase, receptor, type 3 isofo...
FGFR2                 0.061   fibroblast growth factor receptor 2 isoform 9 precu...
FGFR2                 0.061   fibroblast growth factor receptor 2 isoform 3 precu...
FGFR2                 0.061   fibroblast growth factor receptor 2 isoform 8 precu...
FGFR2                 0.061   fibroblast growth factor receptor 2 isoform 7 precu...
FGFR2                 0.061   fibroblast growth factor receptor 2 isoform 6 precu...
FGFR2                 0.061   fibroblast growth factor receptor 2 isoform 5 precu...
FGFR2                 0.061   fibroblast growth factor receptor 2 isoform 4 precu...
FGFR2                 0.061   fibroblast growth factor receptor 2 isoform 1 precu...
FGFR2                 0.061   fibroblast growth factor receptor 2 isoform 2 precu...
NTRK2                 0.060   neurotrophic tyrosine kinase, receptor, type 2 isofo...
NTRK2                 0.060   neurotrophic tyrosine kinase, receptor, type 2 isofo...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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