Search of human proteins with 38488716

Search of human proteins with 38488716

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38488716 DEP domain containing 1 isoform b [Homo sapiens]
         (527 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38488716 DEP domain containing 1 isoform b [Homo sapiens]         1072   0.0  
gi|166295188 DEP domain containing 1 isoform a [Homo sapiens]         627   e-180
gi|223633999 DEP domain containing 1B isoform 1 [Homo sapiens]        551   e-157
gi|223633997 DEP domain containing 1B isoform 2 [Homo sapiens]        461   e-130
gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens]          129   9e-30
gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens]          127   2e-29
gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]            65   1e-10
gi|22748695 DEP domain containing 4 [Homo sapiens]                     62   1e-09
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                50   5e-06
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]    48   2e-05
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi...    48   2e-05
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi...    48   2e-05
gi|215820652 StAR-related lipid transfer (START) domain containi...    46   7e-05
gi|215820650 StAR-related lipid transfer (START) domain containi...    46   7e-05
gi|31543659 StAR-related lipid transfer (START) domain containin...    46   7e-05
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]    45   1e-04
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]     45   1e-04
gi|41281907 StAR-related lipid transfer (START) domain containin...    45   2e-04
gi|16445031 StAR-related lipid transfer (START) domain containin...    45   2e-04
gi|41281898 StAR-related lipid transfer (START) domain containin...    45   2e-04
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap...    44   4e-04
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap...    44   4e-04
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]            44   5e-04
gi|23510413 sorting nexin 26 [Homo sapiens]                            43   6e-04
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]        43   6e-04
gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap...    43   8e-04
gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap...    43   8e-04
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]         42   0.001
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]         42   0.001
gi|54860105 nadrin isoform 2 [Homo sapiens]                            41   0.002

>gi|38488716 DEP domain containing 1 isoform b [Homo sapiens]
          Length = 527

 Score = 1072 bits (2773), Expect = 0.0
 Identities = 527/527 (100%), Positives = 527/527 (100%)

Query: 1   MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
           MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN
Sbjct: 1   MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60

Query: 61  SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120
           SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP
Sbjct: 61  SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120

Query: 121 ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE 180
           ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE
Sbjct: 121 ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE 180

Query: 181 LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS 240
           LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS
Sbjct: 181 LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS 240

Query: 241 DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV 300
           DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV
Sbjct: 241 DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV 300

Query: 301 NILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRS 360
           NILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRS
Sbjct: 301 NILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRS 360

Query: 361 LMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGH 420
           LMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGH
Sbjct: 361 LMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGH 420

Query: 421 IENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKL 480
           IENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKL
Sbjct: 421 IENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKL 480

Query: 481 KQFQKEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR 527
           KQFQKEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR
Sbjct: 481 KQFQKEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR 527


>gi|166295188 DEP domain containing 1 isoform a [Homo sapiens]
          Length = 811

 Score =  627 bits (1617), Expect = e-180
 Identities = 303/303 (100%), Positives = 303/303 (100%)

Query: 1   MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
           MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN
Sbjct: 1   MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60

Query: 61  SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120
           SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP
Sbjct: 61  SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120

Query: 121 ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE 180
           ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE
Sbjct: 121 ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE 180

Query: 181 LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS 240
           LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS
Sbjct: 181 LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS 240

Query: 241 DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV 300
           DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV
Sbjct: 241 DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV 300

Query: 301 NIL 303
           NIL
Sbjct: 301 NIL 303



 Score =  447 bits (1150), Expect = e-125
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 305 LLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIH 364
           LLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIH
Sbjct: 589 LLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIH 648

Query: 365 TFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENP 424
           TFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENP
Sbjct: 649 TFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENP 708

Query: 425 GDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQ 484
           GDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQ
Sbjct: 709 GDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQ 768

Query: 485 KEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR 527
           KEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR
Sbjct: 769 KEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR 811


>gi|223633999 DEP domain containing 1B isoform 1 [Homo sapiens]
          Length = 529

 Score =  551 bits (1419), Expect = e-157
 Identities = 282/531 (53%), Positives = 379/531 (71%), Gaps = 24/531 (4%)

Query: 1   MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
           ME + V PGPYRAT+LWNE    FRA MPLRKHR  FK Y +CFTA EAVDWL++LLR +
Sbjct: 1   MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS 60

Query: 61  SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120
            NFGPEVTR+QT+QLL+KFLKNHVIEDIKG+WG E+ +DN  L+RFP +SPLK  P++ P
Sbjct: 61  QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP 120

Query: 121 ELRK-------NNIE-NFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQ 172
             +        N++    S++   +  +   S    KRH + + +    ++ H       
Sbjct: 121 NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHR------ 174

Query: 173 ENAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRG 232
                 R+L++ +VEE+W+ + L YLQ ILG+ SLEEV++ K V  ++I++N+ + SK+G
Sbjct: 175 ------RQLTEANVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQG 228

Query: 233 VVILQNKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLT 292
           VVIL +KS +LPHWVLSAMKCLANWP  +D+  P Y+GFE+DVF+TIADY+  L EPLLT
Sbjct: 229 VVILDDKSKELPHWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLT 288

Query: 293 FEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKL 352
           F  ++ FV++LGLLQ   E+VA++A Q+CCLLLPP NRRKLQLLMRM++R+  N +MP L
Sbjct: 289 FHLFDAFVSVLGLLQK--EKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPL 346

Query: 353 HDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKH 412
            D  GTR+LM+ TFSRC+LC  +EVDLDELLA RLV+FLMD++QEIL+VP  LQT++E+ 
Sbjct: 347 CDGFGTRTLMVQTFSRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEER 406

Query: 413 LDYLKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLP 472
           + +L++  I+ PG  +   L   S+C+QIS +EF+ Q+   SQ  +A LLE +I +  L 
Sbjct: 407 VAHLRRVQIKYPGADMDITLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITDAKLS 466

Query: 473 LKEKRKKLKQFQKEYPLIYQKRFPTTESEAALFGDKPTIKQPMLI--LRKP 521
            KEK+KKLKQFQK YP +YQ+RFPT ES A LF +KP  K  +L+  L+KP
Sbjct: 467 NKEKKKKLKQFQKSYPEVYQERFPTPESAALLFPEKPKPKPQLLMWALKKP 517


>gi|223633997 DEP domain containing 1B isoform 2 [Homo sapiens]
          Length = 467

 Score =  461 bits (1187), Expect = e-130
 Identities = 231/426 (54%), Positives = 311/426 (73%), Gaps = 22/426 (5%)

Query: 1   MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
           ME + V PGPYRAT+LWNE    FRA MPLRKHR  FK Y +CFTA EAVDWL++LLR +
Sbjct: 1   MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS 60

Query: 61  SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120
            NFGPEVTR+QT+QLL+KFLKNHVIEDIKG+WG E+ +DN  L+RFP +SPLK  P++ P
Sbjct: 61  QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP 120

Query: 121 ELRK-------NNI-ENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQ 172
             +        N++    S++   +  +   S    KRH + + +    ++ H       
Sbjct: 121 NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVH------- 173

Query: 173 ENAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRG 232
                 R+L++ +VEE+W+ + L YLQ ILG+ SLEEV++ K V  ++I++N+ + SK+G
Sbjct: 174 -----RRQLTEANVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQG 228

Query: 233 VVILQNKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLT 292
           VVIL +KS +LPHWVLSAMKCLANWP  +D+  P Y+GFE+DVF+TIADY+  L EPLLT
Sbjct: 229 VVILDDKSKELPHWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLT 288

Query: 293 FEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKL 352
           F  ++ FV++LGLLQ   E+VA++A Q+CCLLLPP NRRKLQLLMRM++R+  N +MP L
Sbjct: 289 FHLFDAFVSVLGLLQK--EKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPL 346

Query: 353 HDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKH 412
            D  GTR+LM+ TFSRC+LC  +EVDLDELLA RLV+FLMD++QEIL+VP  LQT++E+ 
Sbjct: 347 CDGFGTRTLMVQTFSRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEER 406

Query: 413 LDYLKK 418
           + +L++
Sbjct: 407 VAHLRR 412



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 36/98 (36%), Positives = 55/98 (56%), Gaps = 11/98 (11%)

Query: 434 TYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPL------KEKRKKLK--QFQK 485
           T+S C   S  E D  ++  ++  +  L++N  +   +PL      +E+   L+  QFQK
Sbjct: 359 TFSRCILCSKDEVDLDELLAARL-VTFLMDNYQEILKVPLALQTSIEERVAHLRRVQFQK 417

Query: 486 EYPLIYQKRFPTTESEAALFGDKPTIKQPMLI--LRKP 521
            YP +YQ+RFPT ES A LF +KP  K  +L+  L+KP
Sbjct: 418 SYPEVYQERFPTPESAALLFPEKPKPKPQLLMWALKKP 455


>gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens]
          Length = 511

 Score =  129 bits (323), Expect = 9e-30
 Identities = 116/516 (22%), Positives = 232/516 (44%), Gaps = 56/516 (10%)

Query: 7   PPG------PYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
           PPG      P+ AT +W+ +  + +  + ++K R   K++ +CF   EAVD ++  L  N
Sbjct: 23  PPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQN 82

Query: 61  SNFGP-EVTRQQTIQLLRKFLKNHVIEDIKGR-WGSEN----VDDNNQLFRFPATSPLKT 114
             FG  ++ R + +++ +  +   V E +  + +G +      D +  L+RF       T
Sbjct: 83  KYFGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRF------TT 136

Query: 115 LPRRYPEL-RKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQE 173
           +P +  +L ++N + + ++  D++FK  ++   +         ++  E +  +  N    
Sbjct: 137 IPNQDSQLGKENKLYSPARYADALFKSSDIRSAS--------LEDLWENLSLKPANSPHV 188

Query: 174 NAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIP-------QYIMYNMA 226
           N   +  LS + + EVW+   +  L  ++ +P L+ ++  ++ +P       Q  M N +
Sbjct: 189 NI--SATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSS 246

Query: 227 NTSKRGVVILQNKSDDLPHWVLSAMKCLANWP-------RSNDMNNPTYVGFERDVFRTI 279
           N   RG++   + S +   W+ +A+ CL   P         +    P      +++    
Sbjct: 247 NYLDRGILKAYSDSQE-DEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDA 305

Query: 280 ADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRM 339
              +    EPLL     ++   I  LL      +A++A QL   LL   NR + + L+  
Sbjct: 306 IGRYYSSREPLLN-HLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYF 364

Query: 340 ISRMSQNVDMPKLHDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEIL 399
           ++ ++ N    KL      R ++   FS+ ++   +  +L +     LV FLMDH +++ 
Sbjct: 365 MA-VAANPSEFKLQKESDNRMVVKRIFSKAIV---DNKNLSKGKTDLLVLFLMDHQKDVF 420

Query: 400 QVPSYLQTAVEKHLDYLKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIA 459
           ++P  L   V   L  ++ G   N   G       Y YC++I  +++      T++  + 
Sbjct: 421 KIPGTLHKIVSVKLMAIQNGRDPNRDAG-------YIYCQRIDQRDYSNNTEKTTKDELL 473

Query: 460 ELLENIIKNRSLPLKEKRKKLKQFQKEYPLIYQKRF 495
            LL+ + ++  L  KEK+K L QF K +P I+ + F
Sbjct: 474 NLLKTLDEDSKLSAKEKKKLLGQFYKCHPDIFIEHF 509


>gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens]
          Length = 502

 Score =  127 bits (320), Expect = 2e-29
 Identities = 113/507 (22%), Positives = 229/507 (45%), Gaps = 50/507 (9%)

Query: 10  PYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGP-EVT 68
           P+ AT +W+ +  + +  + ++K R   K++ +CF   EAVD ++  L  N  FG  ++ 
Sbjct: 23  PFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIP 82

Query: 69  RQQTIQLLRKFLKNHVIEDIKGR-WGSEN----VDDNNQLFRFPATSPLKTLPRRYPEL- 122
           R + +++ +  +   V E +  + +G +      D +  L+RF       T+P +  +L 
Sbjct: 83  RAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRF------TTIPNQDSQLG 136

Query: 123 RKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRELS 182
           ++N + + ++  D++FK  ++   +         ++  E +  +  N    N   +  LS
Sbjct: 137 KENKLYSPARYADALFKSSDIRSAS--------LEDLWENLSLKPANSPHVNI--SATLS 186

Query: 183 QEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIP-------QYIMYNMANTSKRGVVI 235
            + + EVW+   +  L  ++ +P L+ ++  ++ +P       Q  M N +N   RG++ 
Sbjct: 187 PQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGILK 246

Query: 236 LQNKSDDLPHWVLSAMKCLANWP-------RSNDMNNPTYVGFERDVFRTIADYFLDLPE 288
             + S +   W+ +A+ CL   P         +    P      +++       +    E
Sbjct: 247 AYSDSQE-DEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSSRE 305

Query: 289 PLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVD 348
           PLL     ++   I  LL      +A++A QL   LL   NR + + L+  ++ ++ N  
Sbjct: 306 PLLN-HLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMA-VAANPS 363

Query: 349 MPKLHDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTA 408
             KL      R ++   FS+ ++   +  +L +     LV FLMDH +++ ++P  L   
Sbjct: 364 EFKLQKESDNRMVVKRIFSKAIV---DNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKI 420

Query: 409 VEKHLDYLKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKN 468
           V   L  ++ G   N   G       Y YC++I  +++      T++  +  LL+ + ++
Sbjct: 421 VSVKLMAIQNGRDPNRDAG-------YIYCQRIDQRDYSNNTEKTTKDELLNLLKTLDED 473

Query: 469 RSLPLKEKRKKLKQFQKEYPLIYQKRF 495
             L  KEK+K L QF K +P I+ + F
Sbjct: 474 SKLSAKEKKKLLGQFYKCHPDIFIEHF 500


>gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]
          Length = 494

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 68/262 (25%), Positives = 123/262 (46%), Gaps = 34/262 (12%)

Query: 263 MNNPTYVGFERDVFR-----TIADYFL-DLPEPLLTFEYYELFVNILGLLQ--------- 307
           +NN T +  E   F      T+   FL +LPEPLLT +++   + I  L+Q         
Sbjct: 158 LNNGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTN 217

Query: 308 -PHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHT- 365
            P  +R  I+ALQL  L+LPPPNR  L+LL+ ++ + ++  D  K+           H  
Sbjct: 218 IPDKDR-QIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVL 276

Query: 366 FSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENPG 425
           + + V     + ++ +L +G  ++F++ H Q++ + P+Y++     H  YL      +  
Sbjct: 277 WPKNVTANDLQENITKLNSG--MAFMIKHSQKLFKAPAYIRECARLH--YLGSRTQASKD 332

Query: 426 D-GLFAPLPTYSY-------CKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKR 477
           D  L A   T S+         ++ +    E+    ++ A+ EL +++     +P   K+
Sbjct: 333 DLDLIASCHTKSFQLAKSQKRNRVDSCPHQEETQHHTEEALRELFQHV---HDMPESAKK 389

Query: 478 KKL-KQFQKEYPLIYQKRFPTT 498
           K+L +QF K+       R P+T
Sbjct: 390 KQLIRQFNKQSLTQTPGREPST 411


>gi|22748695 DEP domain containing 4 [Homo sapiens]
          Length = 294

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 27/218 (12%)

Query: 9   GPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVD-WLYDLLRNNSNFGPEV 67
           GP++AT+LW+ +  S +A + +++ R H + Y +CFT  +AVD  L  L++N      ++
Sbjct: 56  GPFQATQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDI 115

Query: 68  TRQQTIQLLRKFLKNHVIEDI------KGRWGSENVDDNNQLFRFPATSPLKTLPRRYPE 121
           +  + + L +  + + V E +      K     E  D N  L+RF               
Sbjct: 116 SCLKGVHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLG------------- 162

Query: 122 LRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQ------ENA 175
             K++ +   + KD+  +     R   +     L+QE GE+   E+I+          N 
Sbjct: 163 -NKSSYDCCKRQKDAENEFNETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNI 221

Query: 176 IDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINP 213
              +   +   E+VW+   L+ L  ++ +P L+ ++ P
Sbjct: 222 TVQKPFLRLSKEDVWKEQTLLCLLQLIHLPFLDNILEP 259


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 24/74 (32%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 279 IADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMR 338
           +  Y  +LPEPL+TF+ Y+ ++    L +P      + ALQ  C  LPP N   L+ LM+
Sbjct: 348 LKSYLRELPEPLMTFDLYDDWMRAASLKEPGAR---LQALQEVCSRLPPENLSNLRYLMK 404

Query: 339 MISRMSQNVDMPKL 352
            ++R+++  ++ K+
Sbjct: 405 FLARLAEEQEVNKM 418


>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
          Length = 771

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 28/75 (37%), Positives = 44/75 (58%), Gaps = 4/75 (5%)

Query: 274 DVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKL 333
           DV   + ++  D+P+PLLT E Y  F+N L LL+P  +   +  LQL   LLPP N   L
Sbjct: 261 DVAALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQ---LGTLQLLIYLLPPCNCDTL 316

Query: 334 QLLMRMISRMSQNVD 348
             L++ +S ++++ D
Sbjct: 317 HRLLQFLSIVARHAD 331


>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
           sapiens]
          Length = 765

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 28/75 (37%), Positives = 44/75 (58%), Gaps = 4/75 (5%)

Query: 274 DVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKL 333
           DV   + ++  D+P+PLLT E Y  F+N L LL+P  +   +  LQL   LLPP N   L
Sbjct: 464 DVAALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQ---LGTLQLLIYLLPPCNCDTL 519

Query: 334 QLLMRMISRMSQNVD 348
             L++ +S ++++ D
Sbjct: 520 HRLLQFLSIVARHAD 534


>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
           sapiens]
          Length = 974

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 28/75 (37%), Positives = 44/75 (58%), Gaps = 4/75 (5%)

Query: 274 DVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKL 333
           DV   + ++  D+P+PLLT E Y  F+N L LL+P  +   +  LQL   LLPP N   L
Sbjct: 464 DVAALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQ---LGTLQLLIYLLPPCNCDTL 519

Query: 334 QLLMRMISRMSQNVD 348
             L++ +S ++++ D
Sbjct: 520 HRLLQFLSIVARHAD 534


>gi|215820652 StAR-related lipid transfer (START) domain containing
           8 isoform b [Homo sapiens]
          Length = 1023

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 46/147 (31%), Positives = 64/147 (43%), Gaps = 14/147 (9%)

Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
           Q + GVP L  V    Q +PQ I   M     + +       D +  +  S +K      
Sbjct: 567 QHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCL-------DQVGIFRKSGVKSRIQNL 619

Query: 259 RSNDMNNPTYVGFERDVFRTIAD----YFLDLPEPLLTFEYYELFVNILGLLQPHLERVA 314
           R  +  +P  V +E      +AD    YF DLPEP+ T +    F+ I  LL P  + +A
Sbjct: 620 RQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLL-PKDQWLA 678

Query: 315 IDALQLCCLLLPPPNRRKLQLLMRMIS 341
             A Q   LLLP  NR  LQ L+  +S
Sbjct: 679 --AAQAATLLLPDENREVLQTLLYFLS 703


>gi|215820650 StAR-related lipid transfer (START) domain containing
           8 isoform a [Homo sapiens]
          Length = 1103

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 46/147 (31%), Positives = 64/147 (43%), Gaps = 14/147 (9%)

Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
           Q + GVP L  V    Q +PQ I   M     + +       D +  +  S +K      
Sbjct: 647 QHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCL-------DQVGIFRKSGVKSRIQNL 699

Query: 259 RSNDMNNPTYVGFERDVFRTIAD----YFLDLPEPLLTFEYYELFVNILGLLQPHLERVA 314
           R  +  +P  V +E      +AD    YF DLPEP+ T +    F+ I  LL P  + +A
Sbjct: 700 RQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLL-PKDQWLA 758

Query: 315 IDALQLCCLLLPPPNRRKLQLLMRMIS 341
             A Q   LLLP  NR  LQ L+  +S
Sbjct: 759 --AAQAATLLLPDENREVLQTLLYFLS 783


>gi|31543659 StAR-related lipid transfer (START) domain containing 8
           isoform b [Homo sapiens]
          Length = 1023

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 46/147 (31%), Positives = 64/147 (43%), Gaps = 14/147 (9%)

Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
           Q + GVP L  V    Q +PQ I   M     + +       D +  +  S +K      
Sbjct: 567 QHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCL-------DQVGIFRKSGVKSRIQNL 619

Query: 259 RSNDMNNPTYVGFERDVFRTIAD----YFLDLPEPLLTFEYYELFVNILGLLQPHLERVA 314
           R  +  +P  V +E      +AD    YF DLPEP+ T +    F+ I  LL P  + +A
Sbjct: 620 RQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLL-PKDQWLA 678

Query: 315 IDALQLCCLLLPPPNRRKLQLLMRMIS 341
             A Q   LLLP  NR  LQ L+  +S
Sbjct: 679 --AAQAATLLLPDENREVLQTLLYFLS 703


>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
          Length = 2087

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 5/93 (5%)

Query: 262 DMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAI-DALQL 320
           D+    YV     V      YF +LP PLLT++ YE F + +         + I D +Q 
Sbjct: 429 DLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQ- 487

Query: 321 CCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLH 353
               LPPP+ R L+ LMR +S ++    +  +H
Sbjct: 488 ---QLPPPHYRTLEFLMRHLSLLADYCSITNMH 517


>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
          Length = 1738

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 5/93 (5%)

Query: 262 DMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAI-DALQL 320
           D+    YV     V      YF +LP PLLT++ YE F + +         + I D +Q 
Sbjct: 80  DLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQ- 138

Query: 321 CCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLH 353
               LPPP+ R L+ LMR +S ++    +  +H
Sbjct: 139 ---QLPPPHYRTLEFLMRHLSLLADYCSITNMH 168


>gi|41281907 StAR-related lipid transfer (START) domain containing
           13 isoform beta [Homo sapiens]
          Length = 1105

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 14/143 (9%)

Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
           + + GVP +  V    Q +PQ I   +         +  N  D +  +  S +K   +  
Sbjct: 650 KAVFGVPLIVHVQRTGQPLPQSIQQALR-------YLRSNCLDQVGLFRKSGVKSRIHAL 702

Query: 259 RSNDMNNPTYVGFER----DVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVA 314
           R  + N P  V +E     DV   +  +F DLPEPL T +  E F++I   +    +   
Sbjct: 703 RQMNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVS---KEQR 759

Query: 315 IDALQLCCLLLPPPNRRKLQLLM 337
           + A+Q   LLL   NR  LQ L+
Sbjct: 760 LQAVQAAILLLADENREVLQTLL 782


>gi|16445031 StAR-related lipid transfer (START) domain containing
           13 isoform gamma [Homo sapiens]
          Length = 995

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 14/143 (9%)

Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
           + + GVP +  V    Q +PQ I   +         +  N  D +  +  S +K   +  
Sbjct: 540 KAVFGVPLIVHVQRTGQPLPQSIQQALR-------YLRSNCLDQVGLFRKSGVKSRIHAL 592

Query: 259 RSNDMNNPTYVGFER----DVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVA 314
           R  + N P  V +E     DV   +  +F DLPEPL T +  E F++I   +    +   
Sbjct: 593 RQMNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVS---KEQR 649

Query: 315 IDALQLCCLLLPPPNRRKLQLLM 337
           + A+Q   LLL   NR  LQ L+
Sbjct: 650 LQAVQAAILLLADENREVLQTLL 672


>gi|41281898 StAR-related lipid transfer (START) domain containing
           13 isoform alpha [Homo sapiens]
          Length = 1113

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 14/143 (9%)

Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
           + + GVP +  V    Q +PQ I   +         +  N  D +  +  S +K   +  
Sbjct: 658 KAVFGVPLIVHVQRTGQPLPQSIQQALR-------YLRSNCLDQVGLFRKSGVKSRIHAL 710

Query: 259 RSNDMNNPTYVGFER----DVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVA 314
           R  + N P  V +E     DV   +  +F DLPEPL T +  E F++I   +    +   
Sbjct: 711 RQMNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVS---KEQR 767

Query: 315 IDALQLCCLLLPPPNRRKLQLLM 337
           + A+Q   LLL   NR  LQ L+
Sbjct: 768 LQAVQAAILLLADENREVLQTLL 790


>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
           sapiens]
          Length = 890

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 5/96 (5%)

Query: 259 RSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILGL-LQPHLERVAIDA 317
           R  D+    Y+     V      YF +LP+PLLT+  Y+ F   +G+ L+P      ++ 
Sbjct: 74  RKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEV 133

Query: 318 LQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLH 353
           L+     LP PN R L+ LMR +  M+       +H
Sbjct: 134 LR----ELPVPNYRTLEFLMRHLVHMASFSAQTNMH 165


>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
           sapiens]
          Length = 1101

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 5/96 (5%)

Query: 259 RSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILGL-LQPHLERVAIDA 317
           R  D+    Y+     V      YF +LP+PLLT+  Y+ F   +G+ L+P      ++ 
Sbjct: 74  RKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEV 133

Query: 318 LQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLH 353
           L+     LP PN R L+ LMR +  M+       +H
Sbjct: 134 LR----ELPVPNYRTLEFLMRHLVHMASFSAQTNMH 165


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 34/132 (25%), Positives = 66/132 (50%), Gaps = 9/132 (6%)

Query: 217 IPQYIMYNMANTSKRGVVI--LQNKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERD 274
           +P+++   + +  + G+ I  +   S +L   V+  ++   N     D+N+  +      
Sbjct: 669 VPKFVKLCIEHVEEHGLDIDGIYRVSGNLA--VIQKLRFAVNHDEKLDLNDSKWEDIHV- 725

Query: 275 VFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQ 334
           +   +  +F +LPEPL TF ++  FVN   + Q   +RVA  A++     LP PN+  +Q
Sbjct: 726 ITGALKMFFRELPEPLFTFNHFNDFVN--AIKQEPRQRVA--AVKDLIRQLPKPNQDTMQ 781

Query: 335 LLMRMISRMSQN 346
           +L R + R+ +N
Sbjct: 782 ILFRHLRRVIEN 793


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 5/96 (5%)

Query: 259 RSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAI-DA 317
           R  +++ P ++     V      YF +LP PLLT++ Y  F   + +       V + D 
Sbjct: 369 RIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDV 428

Query: 318 LQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLH 353
           +Q     LPPP+ R L+ L+R ++RM+++     +H
Sbjct: 429 IQQ----LPPPHYRTLEYLLRHLARMARHSANTSMH 460


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 3/74 (4%)

Query: 279 IADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMR 338
           +  Y  +LPEPL+TFE Y+ ++    + +   +   + AL   C  LP  N   ++ L++
Sbjct: 327 LKSYLRELPEPLMTFELYDEWIQASNVQE---QDKKLQALWNACEKLPKANHNNIRYLIK 383

Query: 339 MISRMSQNVDMPKL 352
            +S++S+  D+ K+
Sbjct: 384 FLSKLSEYQDVNKM 397


>gi|59710113 Rho GTPase activating protein 28 isoform a [Homo
           sapiens]
          Length = 570

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 36/136 (26%), Positives = 65/136 (47%), Gaps = 14/136 (10%)

Query: 282 YFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMIS 341
           +F +LP  L   EY   F++++    PH+ +V   AL L  + LP  NR   Q LM   +
Sbjct: 303 FFRELPTSLFPVEYIPAFISLME-RGPHV-KVQFQALHLMVMALPDANRDAAQALMTFFN 360

Query: 342 RMSQNVDMPKLHDAMGTRSLMIHT--FSRCVLCCAEEVDLDELL----AGRLVSFLMDHH 395
           ++  N    ++       ++M     FSR     ++  D +ELL    A  ++  ++ + 
Sbjct: 361 KVIANESKNRM-SLWNISTVMAPNLFFSR-----SKHSDYEELLLANTAAHIIRLMLKYQ 414

Query: 396 QEILQVPSYLQTAVEK 411
           + + +VPS+L T V +
Sbjct: 415 KILWKVPSFLITQVRR 430


>gi|59710111 Rho GTPase activating protein 28 isoform b [Homo
           sapiens]
          Length = 563

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 36/136 (26%), Positives = 65/136 (47%), Gaps = 14/136 (10%)

Query: 282 YFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMIS 341
           +F +LP  L   EY   F++++    PH+ +V   AL L  + LP  NR   Q LM   +
Sbjct: 303 FFRELPTSLFPVEYIPAFISLME-RGPHV-KVQFQALHLMVMALPDANRDAAQALMTFFN 360

Query: 342 RMSQNVDMPKLHDAMGTRSLMIHT--FSRCVLCCAEEVDLDELL----AGRLVSFLMDHH 395
           ++  N    ++       ++M     FSR     ++  D +ELL    A  ++  ++ + 
Sbjct: 361 KVIANESKNRM-SLWNISTVMAPNLFFSR-----SKHSDYEELLLANTAAHIIRLMLKYQ 414

Query: 396 QEILQVPSYLQTAVEK 411
           + + +VPS+L T V +
Sbjct: 415 KILWKVPSFLITQVRR 430


>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
          Length = 1528

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 3/74 (4%)

Query: 274  DVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKL 333
            DV   +  YF DLPEPL+T +  E F+ I   + P  +R  + A++   +LLP  NR  L
Sbjct: 1145 DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYV-PKDQR--LQAIKAAIMLLPDENREVL 1201

Query: 334  QLLMRMISRMSQNV 347
            Q L+  +S ++  V
Sbjct: 1202 QTLLYFLSDVTAAV 1215


>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
          Length = 1091

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 3/74 (4%)

Query: 274 DVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKL 333
           DV   +  YF DLPEPL+T +  E F+ I   + P  +R  + A++   +LLP  NR  L
Sbjct: 708 DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYV-PKDQR--LQAIKAAIMLLPDENREVL 764

Query: 334 QLLMRMISRMSQNV 347
           Q L+  +S ++  V
Sbjct: 765 QTLLYFLSDVTAAV 778


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 43/199 (21%), Positives = 79/199 (39%), Gaps = 21/199 (10%)

Query: 279 IADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMR 338
           +  Y  +LPEPL+TF  YE +  +  +     +   +  L   C  LPP N    + L++
Sbjct: 324 LKSYLRELPEPLMTFNLYEEWTQVASVQD---QDKKLQDLWRTCQKLPPQNFVNFRYLIK 380

Query: 339 MISRMSQNVDMPKLHDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEI 398
            +++++Q  D+ K+     T S +       +L    E  L E+ A   V     H   +
Sbjct: 381 FLAKLAQTSDVNKM-----TPSNIAIVLGPNLLWARNEGTLAEMAAATSV-----HVVAV 430

Query: 399 LQVPSYLQTAVEKHLDYLKKGHIENPGDGLFAPLPTYSYCKQI-SAQEFDEQKVSTSQAA 457
           ++        + +H D+     +E      F PL T S      +  + D   +   + A
Sbjct: 431 IE-------PIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERKRPA 483

Query: 458 IAELLENIIKNRSLPLKEK 476
              ++E  +  +  P K K
Sbjct: 484 SMAVMEGDLVKKESPPKPK 502


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,751,908
Number of Sequences: 37866
Number of extensions: 938062
Number of successful extensions: 2903
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 2807
Number of HSP's gapped (non-prelim): 112
length of query: 527
length of database: 18,247,518
effective HSP length: 107
effective length of query: 420
effective length of database: 14,195,856
effective search space: 5962259520
effective search space used: 5962259520
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.