BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Homo sapiens] (286 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Ho... 565 e-161 gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Ho... 438 e-123 gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Ho... 391 e-109 gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Ho... 358 4e-99 gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Ho... 298 5e-81 gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 220 1e-57 gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 220 1e-57 gi|38424081 short-chain dehydrogenase/reductase 10 isoform f [Ho... 171 5e-43 gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo s... 90 2e-18 gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo... 75 7e-14 gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens] 75 9e-14 gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A... 72 6e-13 gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Hom... 72 6e-13 gi|5031737 dehydrogenase/reductase member 2 isoform 2 [Homo sapi... 70 2e-12 gi|33667109 dehydrogenase/reductase member 2 isoform 1 [Homo sap... 70 2e-12 gi|4503817 3-ketodihydrosphingosine reductase precursor [Homo sa... 65 9e-11 gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens] 64 1e-10 gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo... 63 3e-10 gi|22507405 short chain dehydrogenase/reductase family 9C, membe... 62 4e-10 gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens] 59 5e-09 gi|146231950 dehydrogenase/reductase (SDR family) member 13 [Hom... 59 6e-09 gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens] 58 1e-08 gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo sap... 57 2e-08 gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 57 2e-08 gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 57 2e-08 gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 57 2e-08 gi|4557649 estradiol 17 beta-dehydrogenase 3 [Homo sapiens] 56 3e-08 gi|150247226 retinol dehydrogenase 16 [Homo sapiens] 56 3e-08 gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens] 56 4e-08 gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo... 54 1e-07 >gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Homo sapiens] Length = 286 Score = 565 bits (1455), Expect = e-161 Identities = 286/286 (100%), Positives = 286/286 (100%) Query: 1 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA 60 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA Sbjct: 1 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA 60 Query: 61 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP 120 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP Sbjct: 61 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP 120 Query: 121 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA 180 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA Sbjct: 121 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA 180 Query: 181 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAV 240 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAV Sbjct: 181 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAV 240 Query: 241 IRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 286 IRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA Sbjct: 241 IRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 286 >gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Homo sapiens] Length = 315 Score = 438 bits (1127), Expect = e-123 Identities = 224/226 (99%), Positives = 224/226 (99%) Query: 1 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA 60 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA Sbjct: 1 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA 60 Query: 61 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP 120 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP Sbjct: 61 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP 120 Query: 121 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA 180 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA Sbjct: 121 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA 180 Query: 181 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 226 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVR T Sbjct: 181 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSST 226 >gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Homo sapiens] Length = 199 Score = 391 bits (1005), Expect = e-109 Identities = 199/199 (100%), Positives = 199/199 (100%) Query: 88 MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 147 MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS Sbjct: 1 MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 60 Query: 148 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 207 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM Sbjct: 61 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 120 Query: 208 CVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWL 267 CVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWL Sbjct: 121 CVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWL 180 Query: 268 PRPRAWFIRQELNVTAAAA 286 PRPRAWFIRQELNVTAAAA Sbjct: 181 PRPRAWFIRQELNVTAAAA 199 >gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Homo sapiens] Length = 205 Score = 358 bits (918), Expect = 4e-99 Identities = 181/181 (100%), Positives = 181/181 (100%) Query: 106 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 165 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS Sbjct: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 84 Query: 166 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 225 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV Sbjct: 85 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 144 Query: 226 TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA 285 TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA Sbjct: 145 TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA 204 Query: 286 A 286 A Sbjct: 205 A 205 Score = 57.4 bits (137), Expect = 1e-08 Identities = 25/27 (92%), Positives = 25/27 (92%) Query: 1 MKVLLLTGLGALFFAYYWDDNFDPASL 27 MKVLLLTGLGALFFAYYWDDNFDP L Sbjct: 1 MKVLLLTGLGALFFAYYWDDNFDPGGL 27 >gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Homo sapiens] Length = 152 Score = 298 bits (762), Expect = 5e-81 Identities = 152/152 (100%), Positives = 152/152 (100%) Query: 135 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 194 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR Sbjct: 1 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60 Query: 195 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 254 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP Sbjct: 61 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 120 Query: 255 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 286 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA Sbjct: 121 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 152 >gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] Length = 292 Score = 220 bits (561), Expect = 1e-57 Identities = 124/256 (48%), Positives = 162/256 (63%), Gaps = 4/256 (1%) Query: 1 MKVLLLTGLGALFFAYYW---DDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLV 57 MK LL LG LF AYY+ ++ F P LQG +V++TGA+ G+G E+AYH A++G+H+V Sbjct: 4 MKKYLLPILG-LFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVV 62 Query: 58 LTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIG 117 +TA ++ LQKVV +C +LGA YIA M E V A +GGLD L+LNHI Sbjct: 63 VTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHIT 122 Query: 118 GAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTP 177 R M+VNF+SYV LT ALP L S GS+VVVSSL G+V Sbjct: 123 NTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAA 182 Query: 178 YSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAA 237 YSA+KFALDGFF S+R+E V VNV+IT+CVLGL D +A +AV G+ ++AAP + A Sbjct: 183 YSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA 242 Query: 238 LAVIRGGATRAAGVFY 253 L +I+GGA R V+Y Sbjct: 243 LEIIKGGALRQEEVYY 258 >gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] Length = 292 Score = 220 bits (561), Expect = 1e-57 Identities = 124/256 (48%), Positives = 162/256 (63%), Gaps = 4/256 (1%) Query: 1 MKVLLLTGLGALFFAYYW---DDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLV 57 MK LL LG LF AYY+ ++ F P LQG +V++TGA+ G+G E+AYH A++G+H+V Sbjct: 4 MKKYLLPILG-LFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVV 62 Query: 58 LTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIG 117 +TA ++ LQKVV +C +LGA YIA M E V A +GGLD L+LNHI Sbjct: 63 VTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHIT 122 Query: 118 GAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTP 177 R M+VNF+SYV LT ALP L S GS+VVVSSL G+V Sbjct: 123 NTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAA 182 Query: 178 YSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAA 237 YSA+KFALDGFF S+R+E V VNV+IT+CVLGL D +A +AV G+ ++AAP + A Sbjct: 183 YSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA 242 Query: 238 LAVIRGGATRAAGVFY 253 L +I+GGA R V+Y Sbjct: 243 LEIIKGGALRQEEVYY 258 >gi|38424081 short-chain dehydrogenase/reductase 10 isoform f [Homo sapiens] Length = 181 Score = 171 bits (434), Expect = 5e-43 Identities = 90/92 (97%), Positives = 90/92 (97%) Query: 135 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 194 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR Sbjct: 1 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60 Query: 195 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 226 ELDVQDVNVAITMCVLGLRDRASAAEAVR T Sbjct: 61 ELDVQDVNVAITMCVLGLRDRASAAEAVRSST 92 >gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo sapiens] Length = 339 Score = 90.1 bits (222), Expect = 2e-18 Identities = 60/181 (33%), Positives = 93/181 (51%), Gaps = 4/181 (2%) Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPK---VFYIAADM 88 V +TGA++G+GEELAY ++LG LVL+A L++V C + G K + + D+ Sbjct: 53 VWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDL 112 Query: 89 ASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSR 148 + E+ + L + G +D LV N + S R L+++N++ V LT Sbjct: 113 TDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKC 172 Query: 149 ALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 207 LP + + K G +V V+S+LG + S Y A+K AL GFF LR EL + + Sbjct: 173 VLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNI 232 Query: 208 C 208 C Sbjct: 233 C 233 >gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo sapiens] Length = 325 Score = 75.1 bits (183), Expect = 7e-14 Identities = 53/188 (28%), Positives = 94/188 (50%), Gaps = 8/188 (4%) Query: 25 ASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVV-----GNCRKLGAP 79 A L+ A V++TGA +G+G+E A + G+ LVL L++++ + K+ Sbjct: 48 AYLRNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTH 107 Query: 80 KVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGT-RARSPQATRWLMQVN 138 K + + D+ A + L G +D LV N+ G + GT + + +M+ N Sbjct: 108 KPYLVTFDLTDSGAIVAAAAEILQCFGYVDILV-NNAGISYRGTIMDTTVDVDKRVMETN 166 Query: 139 FVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELD 197 + V LT LPS+ + G +V +SS+ G++ F + Y+A+K A FF LR E++ Sbjct: 167 YFGPVALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEME 226 Query: 198 VQDVNVAI 205 ++ V + Sbjct: 227 QYEIEVTV 234 >gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens] Length = 300 Score = 74.7 bits (182), Expect = 9e-14 Identities = 69/258 (26%), Positives = 113/258 (43%), Gaps = 5/258 (1%) Query: 26 SLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIA 85 S+ G VL+TGA G+G AY +A+L S LVL + L++ C+ LGA KV Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGA-KVHTFV 91 Query: 86 ADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQL 145 D ++ E S + ++G + LV N + A +VN +++ Sbjct: 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151 Query: 146 TSRALPSLT-DSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 204 T LP++T ++ G +V V+S G V F Y ++KFA GF +L EL + Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211 Query: 205 ITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAAL-AVIRGGATRAAGVFYPWRFRLLCLL 263 T C+ + + T + P+ + ++ G T +F P L L Sbjct: 212 KTTCL--CPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTL 269 Query: 264 RRWLPRPRAWFIRQELNV 281 R LP ++Q+++V Sbjct: 270 ERILPERFLAVLKQKISV 287 >gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A [Homo sapiens] Length = 300 Score = 72.0 bits (175), Expect = 6e-13 Identities = 65/259 (25%), Positives = 112/259 (43%), Gaps = 7/259 (2%) Query: 26 SLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIA 85 S+ G VL+TGA G+G + Y +A+ S LVL + +++ CRKLG Y+ Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVV 92 Query: 86 ADMASPEAPESVVQFALDKLGGLDYLVLNHIGGA-PAGTRARSPQATRWLMQVNFVSYVQ 144 E S+ Q + K G +V+N+ G PA + + +VN + + Sbjct: 93 DCSNREEIYRSLNQ--VKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFW 150 Query: 145 LTSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203 +T LPS+ + + G +V V+S+ G + PY ++KFA GF L EL Sbjct: 151 ITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210 Query: 204 AITMCVLGLRDRASAAEAVRGVTRV-KAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCL 262 T C+ + + TR+ + ++I G T +F P + Sbjct: 211 IKTSCLCPV--FVNTGFTKNPSTRLWPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLR 268 Query: 263 LRRWLPRPRAWFIRQELNV 281 L+++LP + + + N+ Sbjct: 269 LQKFLPERASAILNRMQNI 287 >gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Homo sapiens] Length = 311 Score = 72.0 bits (175), Expect = 6e-13 Identities = 58/212 (27%), Positives = 100/212 (47%), Gaps = 10/212 (4%) Query: 1 MKVLLLTGLGALFFAYYWDDN-FDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLT 59 M LLL G+ L F Y + +++Q V++T A +G+G+E A + G+ LVL Sbjct: 8 MLPLLLLGISGLLFIYQEVSRLWSKSAVQNKVVVITDAISGLGKECARVFHTGGARLVLC 67 Query: 60 AHTEALLQKV------VGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVL 113 L+ + V + K PK+ + D++ V + LD G +D L+ Sbjct: 68 GKNWERLENLYDALISVADPSKTFTPKL--VLLDLSDISCVPDVAKEVLDCYGCVDILIN 125 Query: 114 NHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPT 172 N S + + +M N+ + LT LP++ + G +V+V+++ G+ Sbjct: 126 NASVKVKGPAHKISLELDKKIMDANYFGPITLTKALLPNMISRRTGQIVLVNNIQGKFGI 185 Query: 173 SFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 204 F T Y+A+K A GFF LR E++ DV ++ Sbjct: 186 PFRTTYAASKHAALGFFDCLRAEVEEYDVVIS 217 >gi|5031737 dehydrogenase/reductase member 2 isoform 2 [Homo sapiens] Length = 280 Score = 70.1 bits (170), Expect = 2e-12 Identities = 51/175 (29%), Positives = 91/175 (52%), Gaps = 8/175 (4%) Query: 33 LLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPE 92 ++TG+ +G+G +A AR G+H+V+++ + + + + + G V I + E Sbjct: 40 VVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGL-SVAGIVCHVGKAE 98 Query: 93 APESVVQFALDKLGGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSR 148 E +V AL+ GG+D+LV +N + G+ GT S Q ++ VN S L S+ Sbjct: 99 DREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGT---SEQIWDKILSVNVKSPALLLSQ 155 Query: 149 ALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203 LP + + +G++++VSS+ P Y+ +K AL G +L EL +D+ V Sbjct: 156 LLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRV 210 >gi|33667109 dehydrogenase/reductase member 2 isoform 1 [Homo sapiens] Length = 300 Score = 70.1 bits (170), Expect = 2e-12 Identities = 51/175 (29%), Positives = 91/175 (52%), Gaps = 8/175 (4%) Query: 33 LLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPE 92 ++TG+ +G+G +A AR G+H+V+++ + + + + + G V I + E Sbjct: 40 VVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGL-SVAGIVCHVGKAE 98 Query: 93 APESVVQFALDKLGGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSR 148 E +V AL+ GG+D+LV +N + G+ GT S Q ++ VN S L S+ Sbjct: 99 DREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGT---SEQIWDKILSVNVKSPALLLSQ 155 Query: 149 ALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203 LP + + +G++++VSS+ P Y+ +K AL G +L EL +D+ V Sbjct: 156 LLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRV 210 >gi|4503817 3-ketodihydrosphingosine reductase precursor [Homo sapiens] Length = 332 Score = 64.7 bits (156), Expect = 9e-11 Identities = 61/206 (29%), Positives = 104/206 (50%), Gaps = 9/206 (4%) Query: 24 PASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALL---QKVVGNCRKLGAPK 80 P +L GA V++TG ++G+G+ +A + G+ + L A E L +K + Sbjct: 27 PLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQV 86 Query: 81 VFYIAADMASP-EAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQAT-RWLMQVN 138 V I+ D++ E+V++ A +KLG +D LV N G A +G +T LM +N Sbjct: 87 VLCISVDVSQDYNQVENVIKQAQEKLGPVDMLV-NCAGMAVSGKFEDLEVSTFERLMSIN 145 Query: 139 FVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELD 197 ++ V + + ++ + + G +V VSS G++ T YSA+KFA+ G +L +++ Sbjct: 146 YLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEAL--QME 203 Query: 198 VQDVNVAITMCVLGLRDRASAAEAVR 223 V+ NV IT+ D AE R Sbjct: 204 VKPYNVYITVAYPPDTDTPGFAEENR 229 >gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens] Length = 311 Score = 64.3 bits (155), Expect = 1e-10 Identities = 56/176 (31%), Positives = 80/176 (45%), Gaps = 21/176 (11%) Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASP 91 VL++G ++G+G ELA V AH +VV R LG + AA A Sbjct: 8 VLISGCSSGIGLELA----------VQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALG 57 Query: 92 E----------APESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVS 141 + + ESV Q G +D LV N G S A + + NF Sbjct: 58 QTLTVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFG 117 Query: 142 YVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRREL 196 V+L LP + + G +VV+SS++G F+ Y+A+KFAL+GFF SL +L Sbjct: 118 AVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQL 173 >gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo sapiens] Length = 270 Score = 63.2 bits (152), Expect = 3e-10 Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 8/159 (5%) Query: 29 GARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADM 88 G V++TG G+G + + G+ +V+ E+ G + P +I D+ Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDES-----GGRALEQELPGAVFILCDV 63 Query: 89 ASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRAR--SPQATRWLMQVNFVSYVQLT 146 + +++V + + G LD V+N+ G P R S Q R L+++N + LT Sbjct: 64 TQEDDVKTLVSETIRRFGRLD-CVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 Query: 147 SRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFAL 185 ALP L S+G+++ +SSL+G + + + PY A K A+ Sbjct: 123 KLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAV 161 >gi|22507405 short chain dehydrogenase/reductase family 9C, member 7 [Homo sapiens] Length = 313 Score = 62.4 bits (150), Expect = 4e-10 Identities = 60/211 (28%), Positives = 94/211 (44%), Gaps = 23/211 (10%) Query: 6 LTGLGALFFAYYWDDNFD-PASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEA 64 + L L F Y W N + +L V +TG ++G G LA G ++ TE Sbjct: 1 MAALTDLSFMYRWFKNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEE 60 Query: 65 LLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLG--GLDYLVLNHIGGAPAG 122 QK+ ++ + ++ D+ E+ ++ Q+ DK+G GL LV N G P+G Sbjct: 61 GSQKL----QRDTSYRLQTTLLDVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSG 116 Query: 123 TRARSPQATRWL--------MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSF 174 WL + VN V +++T LP + ++G +V +SS GRV Sbjct: 117 PN-------EWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAV-I 168 Query: 175 STPYSAAKFALDGFFGSLRRELDVQDVNVAI 205 Y +KF ++ F S+RREL V V I Sbjct: 169 GGGYCVSKFGVEAFSDSIRRELYYFGVKVCI 199 >gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens] Length = 309 Score = 58.9 bits (141), Expect = 5e-09 Identities = 52/177 (29%), Positives = 80/177 (45%), Gaps = 5/177 (2%) Query: 26 SLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIA 85 ++ G VL+TGA +G+G LA +ARLGS LVL + ++ R+ GA +V Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYT 96 Query: 86 ADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARS--PQATRWLMQVNFVSYV 143 D + E V ++G + L+ N G G + + VNF +++ Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINN--AGIVTGKKFLDCPDELMEKSFDVNFKAHL 154 Query: 144 QLTSRALPS-LTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQ 199 LP+ + + G LV +SS G + Y A+KFA GF S+ E VQ Sbjct: 155 WTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQ 211 >gi|146231950 dehydrogenase/reductase (SDR family) member 13 [Homo sapiens] Length = 377 Score = 58.5 bits (140), Expect = 6e-09 Identities = 69/242 (28%), Positives = 104/242 (42%), Gaps = 21/242 (8%) Query: 1 MKVLLLTG---LGALFFAYYWDDNFDPA----SLQGARVLLTGANAGVGEELAYHYARLG 53 M+ LLL LGA YY P +L+G ++TGAN+G+G+ A AR G Sbjct: 1 MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRG 60 Query: 54 SHLVLTAHTEALLQKVVGNCR-KLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLV 112 + +VL ++ + + R + G +V ++A D+AS + + L LD L+ Sbjct: 61 ARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILI 120 Query: 113 LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPT 172 N A + R+ +A L++VN + LT LP L S VVV + Sbjct: 121 HN----AGISSCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRG 176 Query: 173 SFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAP 232 + + G+ LR D + N VL R+ A+ EA GVT A P Sbjct: 177 RLD--FKRLDRPVVGWRQELRAYADTKLAN------VLFARELANQLEAT-GVTCYAAHP 227 Query: 233 GP 234 GP Sbjct: 228 GP 229 >gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens] Length = 317 Score = 57.8 bits (138), Expect = 1e-08 Identities = 54/207 (26%), Positives = 97/207 (46%), Gaps = 11/207 (5%) Query: 4 LLLTGLGALFFAYYWDDNFDPAS-LQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHT 62 L L L++ +W S LQ V +TG ++G G LA G ++ T Sbjct: 3 LYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLT 62 Query: 63 EALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLG--GLDYLVLNHIGGAP 120 E +++ G + ++ + D+ E+ + Q+ + +G GL LV N+ G Sbjct: 63 EKGAEQLRGQT----SDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLV-NNAGILT 117 Query: 121 AGTRAR--SPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPY 178 T + + + +++VN + +Q+T LP + ++G +V VSS+LGRV F Y Sbjct: 118 PITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRV-AFFVGGY 176 Query: 179 SAAKFALDGFFGSLRRELDVQDVNVAI 205 +K+ ++ F LRRE+ V ++I Sbjct: 177 CVSKYGVEAFSDILRREIQHFGVKISI 203 >gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo sapiens] Length = 318 Score = 56.6 bits (135), Expect = 2e-08 Identities = 55/206 (26%), Positives = 99/206 (48%), Gaps = 19/206 (9%) Query: 9 LGALFFAYYW---DDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEAL 65 LGAL +A W D PAS A V +TG ++G G LA + G ++ + T + Sbjct: 7 LGALLWAVLWLLRDRQSLPAS--NAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSG 64 Query: 66 LQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALD--KLGGLDYLVLNHIGGAPAGT 123 + + +++ + ++ D+ P++ + ++ K GL LV N AG Sbjct: 65 AEDL----QRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNN---AGVAGI 117 Query: 124 RARSPQATR----WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYS 179 +P TR ++ VN + + +T LP L ++G ++ ++S+LGR+ + Y Sbjct: 118 IGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAAN-GGGYC 176 Query: 180 AAKFALDGFFGSLRRELDVQDVNVAI 205 +KF L+ F SLRR++ + V+I Sbjct: 177 VSKFGLEAFSDSLRRDVAHFGIRVSI 202 >gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo sapiens] Length = 343 Score = 56.6 bits (135), Expect = 2e-08 Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%) Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASP 91 VL+TG ++G G LA H G + + V L + ++ + ++ S Sbjct: 58 VLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSS 117 Query: 92 EAPESVVQFALDKLGGLD---YLVLNHIGGAPAG-TRARSPQATRWLMQVNFVSYVQLTS 147 E E VV+ L + + ++N+ G + G S + + + +VN V++T Sbjct: 118 EEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTK 177 Query: 148 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 205 LP + +KG +V +SS+LGR+ +PY KF ++ F LR E+ V V++ Sbjct: 178 SFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSV 235 >gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo sapiens] Length = 343 Score = 56.6 bits (135), Expect = 2e-08 Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%) Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASP 91 VL+TG ++G G LA H G + + V L + ++ + ++ S Sbjct: 58 VLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSS 117 Query: 92 EAPESVVQFALDKLGGLD---YLVLNHIGGAPAG-TRARSPQATRWLMQVNFVSYVQLTS 147 E E VV+ L + + ++N+ G + G S + + + +VN V++T Sbjct: 118 EEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTK 177 Query: 148 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 205 LP + +KG +V +SS+LGR+ +PY KF ++ F LR E+ V V++ Sbjct: 178 SFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSV 235 >gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo sapiens] Length = 343 Score = 56.6 bits (135), Expect = 2e-08 Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%) Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASP 91 VL+TG ++G G LA H G + + V L + ++ + ++ S Sbjct: 58 VLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSS 117 Query: 92 EAPESVVQFALDKLGGLD---YLVLNHIGGAPAG-TRARSPQATRWLMQVNFVSYVQLTS 147 E E VV+ L + + ++N+ G + G S + + + +VN V++T Sbjct: 118 EEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTK 177 Query: 148 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 205 LP + +KG +V +SS+LGR+ +PY KF ++ F LR E+ V V++ Sbjct: 178 SFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSV 235 >gi|4557649 estradiol 17 beta-dehydrogenase 3 [Homo sapiens] Length = 310 Score = 56.2 bits (134), Expect = 3e-08 Identities = 43/182 (23%), Positives = 86/182 (47%), Gaps = 9/182 (4%) Query: 29 GARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADM 88 G ++TGA G+G+ ++ A+ G ++VL + T L+ + + V I AD Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADF 107 Query: 89 ASPEAPESVVQFALDKLGGLDY-LVLNHIGGAP---AGTRARSPQATRWLMQVNFVSYVQ 144 + + + +KL GL+ +++N++G P +P + L+ N S V+ Sbjct: 108 TK----DDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163 Query: 145 LTSRALPSL-TDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203 +T L + + KG ++ +SS + P + YSA+K + F +L+ E ++V + Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVII 223 Query: 204 AI 205 + Sbjct: 224 QV 225 >gi|150247226 retinol dehydrogenase 16 [Homo sapiens] Length = 317 Score = 56.2 bits (134), Expect = 3e-08 Identities = 52/208 (25%), Positives = 98/208 (47%), Gaps = 8/208 (3%) Query: 1 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA 60 M + L +G + +++ + + L+ V +TG ++G G+ LA G ++ Sbjct: 1 MWLYLAVFVGLYYLLHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAAC 60 Query: 61 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLG--GLDYLVLNHIGG 118 TE +++ G + ++ + D+ E+ + Q+ + + GL LV N Sbjct: 61 LTEKGAEQLRGQT----SDRLETVTLDVTKTESVAAAAQWVKECVRDKGLWGLVNNAGIS 116 Query: 119 AP-AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTP 177 P A + Q ++ VN + + +T LP + ++G +V VSS++GRV + F Sbjct: 117 LPTAPNELLTKQDFVTILDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRV-SLFGGG 175 Query: 178 YSAAKFALDGFFGSLRRELDVQDVNVAI 205 Y +K+ ++ F SLRREL V VA+ Sbjct: 176 YCISKYGVEAFSDSLRRELSYFGVKVAM 203 >gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens] Length = 387 Score = 55.8 bits (133), Expect = 4e-08 Identities = 54/181 (29%), Positives = 79/181 (43%), Gaps = 15/181 (8%) Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVG--NCRKLGAPKVFYIAADMA 89 VL+TG + G+G L + LG T L + G R+ +P++ + D+ Sbjct: 85 VLVTGGDCGLGHALCKYLDELG----FTVFAGVLNENGPGAEELRRTCSPRLSVLQMDIT 140 Query: 90 SP----EAPESVVQFALDKLGGLDYLVLNHIG--GAPAGTRARSPQATRWLMQVNFVSYV 143 P +A V D+ GL + V+N+ G G P + M VNF V Sbjct: 141 KPVQIKDAYSKVAAMLQDR--GL-WAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197 Query: 144 QLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203 ++T LP L SKG LV VSS+ G P Y ++K A+ F +R EL + V Sbjct: 198 EVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKV 257 Query: 204 A 204 A Sbjct: 258 A 258 >gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo sapiens] Length = 319 Score = 54.3 bits (129), Expect = 1e-07 Identities = 44/176 (25%), Positives = 88/176 (50%), Gaps = 8/176 (4%) Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASP 91 + +TG ++G G A + + G H++ TE+ + + ++ + D+ P Sbjct: 32 IFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSE----RLRTVLLDVTDP 87 Query: 92 EAPESVVQFALDKLG--GLDYLVLNH-IGGAPAGTRARSPQATRWLMQVNFVSYVQLTSR 148 E + Q+ +++G GL L+ N + G A T + + R ++VN + +T Sbjct: 88 ENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLN 147 Query: 149 ALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 204 LP + ++G ++ VSS+ GR+ Y+ +K+A++GF SLRR++ V+V+ Sbjct: 148 MLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.137 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,249,144 Number of Sequences: 37866 Number of extensions: 430916 Number of successful extensions: 1443 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 52 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 1338 Number of HSP's gapped (non-prelim): 80 length of query: 286 length of database: 18,247,518 effective HSP length: 101 effective length of query: 185 effective length of database: 14,423,052 effective search space: 2668264620 effective search space used: 2668264620 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.