Guide to the Human Genome
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Name: HSD17B6 Sequence: fasta or formatted (317aa) NCBI GI: 19743808
Description:

hydroxysteroid (17-beta) dehydrogenase 6

Referenced in:

Alcohol and Aldehyde Dehydrogenases
Steroid Hormones

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.9         22           3
 C cysteine            1.9          6           1
 D aspartate           3.8         12           1
 E glutamate           5.0         16           1
 F phenylalanine       3.8         12           3
 G glycine             7.3         23           2
 H histidine           2.2          7           1
 I isoleucine          5.0         16           1
 K lysine              4.4         14           1
 L leucine            12.0         38           2
 M methionine          3.2         10           1
 N asparagine          3.8         12           2
 P proline             2.8          9           1
 Q glutamine           4.1         13           2
 R arginine            6.3         20           2
 S serine              6.0         19           2
 T threonine           6.6         21           1
 V valine              7.9         25           2
 W tryptophan          2.5          8           1
 Y tyrosine            4.4         14           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hydroxysteroid (17-beta) dehydrogenase 6 
RDH16                 0.663   retinol dehydrogenase 16 
SDR9C7                0.490   short chain dehydrogenase/reductase family 9C, membe...
RDH5                  0.466   retinol dehydrogenase 5 (11-cis and 9-cis) 
DHRS9                 0.437   NADP-dependent retinol dehydrogenase/reductase [Homo...
DHRS9                 0.437   NADP-dependent retinol dehydrogenase/reductase [Hom...
DHRS9                 0.437   NADP-dependent retinol dehydrogenase/reductase [Hom...
DHRS9                 0.437   NADP-dependent retinol dehydrogenase/reductase [Homo...
BDH1                  0.271   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
BDH1                  0.271   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
BDH1                  0.271   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
HSD17B2               0.219   hydroxysteroid (17-beta) dehydrogenase 2 
HSD11B2               0.211   hydroxysteroid (11-beta) dehydrogenase 2 
DHRS7B                0.111   dehydrogenase/reductase (SDR family) member 7B [Homo...
DHRS7                 0.084   dehydrogenase/reductase (SDR family) member 7 
RDH8                  0.076   retinol dehydrogenase 8 (all-trans) 
RDH12                 0.073   retinol dehydrogenase 12 
CBR4                  0.073   carbonic reductase 4 
RDH11                 0.071   retinol dehydrogenase 11 
HSD17B1               0.071   hydroxysteroid (17-beta) dehydrogenase 1 
RDH13                 0.068   retinol dehydrogenase 13 isoform 1 
HSD11B1               0.066   11-beta-hydroxysteroid dehydrogenase 1 
HSD11B1               0.066   11-beta-hydroxysteroid dehydrogenase 1 
HPGD                  0.065   hydroxyprostaglandin dehydrogenase 15-(NAD) isoform ...
HSD17B13              0.065   hydroxysteroid (17-beta) dehydrogenase 13 isoform A...
HSD17B14              0.063   dehydrogenase/reductase (SDR family) member 10 [Homo...
SDR16C5               0.060   epidermal retinal dehydrogenase 2 
DHRS7C                0.058   dehydrogenase/reductase (SDR family) member 7C [Hom...
RDH14                 0.055   retinol dehydrogenase 14 (all-trans and 9-cis) [Homo...
HSD17B3               0.055   estradiol 17 beta-dehydrogenase 3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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