Guide to the Human Genome
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Search of human proteins with 38424081

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38424081 short-chain dehydrogenase/reductase 10 isoform f
[Homo sapiens]
         (181 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Ho...   362   e-100
gi|38424081 short-chain dehydrogenase/reductase 10 isoform f [Ho...   362   e-100
gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Ho...   171   2e-43
gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Ho...   171   2e-43
gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Ho...   171   2e-43
gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Ho...   171   2e-43
gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]     100   7e-22
gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]      100   7e-22
gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo s...    49   2e-06
gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo...    49   2e-06
gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [H...    46   2e-05
gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [H...    46   2e-05
gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [H...    46   2e-05
gi|150247226 retinol dehydrogenase 16 [Homo sapiens]                   46   2e-05
gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Hom...    46   2e-05
gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens]    46   2e-05
gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]          46   2e-05
gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]     45   3e-05
gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens]         42   3e-04
gi|22507405 short chain dehydrogenase/reductase family 9C, membe...    41   6e-04
gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo...    40   8e-04
gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Hom...    40   8e-04
gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Hom...    40   8e-04
gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo...    40   8e-04
gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo sap...    40   0.001
gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B...    40   0.001
gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A...    40   0.001
gi|7705855 hydroxysteroid (17-beta) dehydrogenase 12 [Homo sapiens]    39   0.003
gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo...    38   0.005
gi|25282469 retinol dehydrogenase 10 [Homo sapiens]                    38   0.005

>gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Homo
           sapiens]
          Length = 315

 Score =  362 bits (929), Expect = e-100
 Identities = 181/181 (100%), Positives = 181/181 (100%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 135 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 194

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGA 120
           ELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGA
Sbjct: 195 ELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGA 254

Query: 121 RTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGH 180
           RTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGH
Sbjct: 255 RTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGH 314

Query: 181 D 181
           D
Sbjct: 315 D 315


>gi|38424081 short-chain dehydrogenase/reductase 10 isoform f [Homo
           sapiens]
          Length = 181

 Score =  362 bits (929), Expect = e-100
 Identities = 181/181 (100%), Positives = 181/181 (100%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGA 120
           ELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGA
Sbjct: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGA 120

Query: 121 RTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGH 180
           RTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGH
Sbjct: 121 RTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGH 180

Query: 181 D 181
           D
Sbjct: 181 D 181


>gi|38424083 short-chain dehydrogenase/reductase 10 isoform d
          [Homo sapiens]
          Length = 152

 Score =  171 bits (434), Expect = 2e-43
 Identities = 90/92 (97%), Positives = 90/92 (97%)

Query: 1  MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
          MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 1  MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60

Query: 61 ELDVQDVNVAITMCVLGLRDRASAAEAVRSST 92
          ELDVQDVNVAITMCVLGLRDRASAAEAVR  T
Sbjct: 61 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 92


>gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Homo
           sapiens]
          Length = 205

 Score =  171 bits (434), Expect = 2e-43
 Identities = 90/92 (97%), Positives = 90/92 (97%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 54  MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 113

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRSST 92
           ELDVQDVNVAITMCVLGLRDRASAAEAVR  T
Sbjct: 114 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 145


>gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Homo
           sapiens]
          Length = 199

 Score =  171 bits (434), Expect = 2e-43
 Identities = 90/92 (97%), Positives = 90/92 (97%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 48  MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 107

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRSST 92
           ELDVQDVNVAITMCVLGLRDRASAAEAVR  T
Sbjct: 108 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 139


>gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Homo
           sapiens]
          Length = 286

 Score =  171 bits (434), Expect = 2e-43
 Identities = 90/92 (97%), Positives = 90/92 (97%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 135 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 194

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRSST 92
           ELDVQDVNVAITMCVLGLRDRASAAEAVR  T
Sbjct: 195 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 226


>gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
          Length = 292

 Score =  100 bits (249), Expect = 7e-22
 Identities = 53/88 (60%), Positives = 64/88 (72%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           M+VNF+SYV LT  ALP L  S GS+VVVSSL G+V       YSA+KFALDGFF S+R+
Sbjct: 140 MEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRK 199

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAV 88
           E  V  VNV+IT+CVLGL D  +A +AV
Sbjct: 200 EYSVSRVNVSITLCVLGLIDTETAMKAV 227


>gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
          Length = 292

 Score =  100 bits (249), Expect = 7e-22
 Identities = 53/88 (60%), Positives = 64/88 (72%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           M+VNF+SYV LT  ALP L  S GS+VVVSSL G+V       YSA+KFALDGFF S+R+
Sbjct: 140 MEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRK 199

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAV 88
           E  V  VNV+IT+CVLGL D  +A +AV
Sbjct: 200 EYSVSRVNVSITLCVLGLIDTETAMKAV 227


>gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo
           sapiens]
          Length = 339

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 1/75 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 59
           +++N++  V LT   LP + + K G +V V+S+LG +    S  Y A+K AL GFF  LR
Sbjct: 159 IELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLR 218

Query: 60  RELDVQDVNVAITMC 74
            EL      +   +C
Sbjct: 219 TELATYPGIIVSNIC 233


>gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo
           sapiens]
          Length = 325

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 1/72 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 59
           M+ N+   V LT   LPS+   + G +V +SS+ G++   F + Y+A+K A   FF  LR
Sbjct: 163 METNYFGPVALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLR 222

Query: 60  RELDVQDVNVAI 71
            E++  ++ V +
Sbjct: 223 AEMEQYEIEVTV 234


>gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
           sapiens]
          Length = 343

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 24/70 (34%), Positives = 39/70 (55%)

Query: 2   QVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRE 61
           +VN    V++T   LP +  +KG +V +SS+LGR+     +PY   KF ++ F   LR E
Sbjct: 166 EVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225

Query: 62  LDVQDVNVAI 71
           +    V V++
Sbjct: 226 MYPLGVKVSV 235


>gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
           sapiens]
          Length = 343

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 24/70 (34%), Positives = 39/70 (55%)

Query: 2   QVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRE 61
           +VN    V++T   LP +  +KG +V +SS+LGR+     +PY   KF ++ F   LR E
Sbjct: 166 EVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225

Query: 62  LDVQDVNVAI 71
           +    V V++
Sbjct: 226 MYPLGVKVSV 235


>gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
           sapiens]
          Length = 343

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 24/70 (34%), Positives = 39/70 (55%)

Query: 2   QVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRE 61
           +VN    V++T   LP +  +KG +V +SS+LGR+     +PY   KF ++ F   LR E
Sbjct: 166 EVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225

Query: 62  LDVQDVNVAI 71
           +    V V++
Sbjct: 226 MYPLGVKVSV 235


>gi|150247226 retinol dehydrogenase 16 [Homo sapiens]
          Length = 317

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 26/71 (36%), Positives = 42/71 (59%), Gaps = 1/71 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           + VN +  + +T   LP +  ++G +V VSS++GRV + F   Y  +K+ ++ F  SLRR
Sbjct: 134 LDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRV-SLFGGGYCISKYGVEAFSDSLRR 192

Query: 61  ELDVQDVNVAI 71
           EL    V VA+
Sbjct: 193 ELSYFGVKVAM 203


>gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Homo
           sapiens]
          Length = 311

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 59
           M  N+   + LT   LP++   + G +V+V+++ G+    F T Y+A+K A  GFF  LR
Sbjct: 147 MDANYFGPITLTKALLPNMISRRTGQIVLVNNIQGKFGIPFRTTYAASKHAALGFFDCLR 206

Query: 60  RELDVQDVNVA 70
            E++  DV ++
Sbjct: 207 AEVEEYDVVIS 217


>gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens]
          Length = 317

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 1/71 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           ++VN +  +Q+T   LP +  ++G +V VSS+LGRV   F   Y  +K+ ++ F   LRR
Sbjct: 134 LKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRV-AFFVGGYCVSKYGVEAFSDILRR 192

Query: 61  ELDVQDVNVAI 71
           E+    V ++I
Sbjct: 193 EIQHFGVKISI 203


>gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]
          Length = 311

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 25/60 (41%), Positives = 37/60 (61%), Gaps = 1/60 (1%)

Query: 4   NFVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRREL 62
           NF   V+L    LP +   + G +VV+SS++G     F+  Y+A+KFAL+GFF SL  +L
Sbjct: 114 NFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQL 173


>gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]
          Length = 387

 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 28/70 (40%), Positives = 36/70 (51%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           M VNF   V++T   LP L  SKG LV VSS+ G  P      Y ++K A+  F   +R 
Sbjct: 189 MAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRL 248

Query: 61  ELDVQDVNVA 70
           EL    + VA
Sbjct: 249 ELSKWGIKVA 258


>gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens]
          Length = 300

 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 8/129 (6%)

Query: 2   QVNFVSYVQLTSRALPSLT-DSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           +VN +++   T   LP++T ++ G +V V+S  G V   F   Y ++KFA  GF  +L  
Sbjct: 142 EVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTD 201

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEH------RGVPLQSQTAMFLP 114
           EL    +    T C+          +   +S     +PE        G+ L  Q  +F+P
Sbjct: 202 ELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGI-LTEQKMIFIP 260

Query: 115 PTVPGARTL 123
            ++    TL
Sbjct: 261 SSIAFLTTL 269


>gi|22507405 short chain dehydrogenase/reductase family 9C, member 7
           [Homo sapiens]
          Length = 313

 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 1/71 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           + VN V  +++T   LP +  ++G +V +SS  GRV       Y  +KF ++ F  S+RR
Sbjct: 130 INVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAV-IGGGYCVSKFGVEAFSDSIRR 188

Query: 61  ELDVQDVNVAI 71
           EL    V V I
Sbjct: 189 ELYYFGVKVCI 199


>gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           ++VN    + +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192

Query: 61  ELDVQDVNVA 70
           ++    V+V+
Sbjct: 193 DMKAFGVHVS 202


>gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           ++VN    + +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192

Query: 61  ELDVQDVNVA 70
           ++    V+V+
Sbjct: 193 DMKAFGVHVS 202


>gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           ++VN    + +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192

Query: 61  ELDVQDVNVA 70
           ++    V+V+
Sbjct: 193 DMKAFGVHVS 202


>gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           ++VN    + +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192

Query: 61  ELDVQDVNVA 70
           ++    V+V+
Sbjct: 193 DMKAFGVHVS 202


>gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo
           sapiens]
          Length = 318

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 22/71 (30%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           + VN +  + +T   LP L  ++G ++ ++S+LGR+  +    Y  +KF L+ F  SLRR
Sbjct: 133 LNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAAN-GGGYCVSKFGLEAFSDSLRR 191

Query: 61  ELDVQDVNVAI 71
           ++    + V+I
Sbjct: 192 DVAHFGIRVSI 202


>gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B
           [Homo sapiens]
          Length = 264

 Score = 39.7 bits (91), Expect = 0.001
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 2   QVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           +VN + +  +T   LPS+ + + G +V V+S+ G     +  PY ++KFA  GF   L  
Sbjct: 106 EVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTS 165

Query: 61  ELDVQDVNVAITMCV 75
           EL         T C+
Sbjct: 166 ELQALGKTGIKTSCL 180


>gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A
           [Homo sapiens]
          Length = 300

 Score = 39.7 bits (91), Expect = 0.001
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 2   QVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           +VN + +  +T   LPS+ + + G +V V+S+ G     +  PY ++KFA  GF   L  
Sbjct: 142 EVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTS 201

Query: 61  ELDVQDVNVAITMCV 75
           EL         T C+
Sbjct: 202 ELQALGKTGIKTSCL 216


>gi|7705855 hydroxysteroid (17-beta) dehydrogenase 12 [Homo sapiens]
          Length = 312

 Score = 38.5 bits (88), Expect = 0.003
 Identities = 44/162 (27%), Positives = 70/162 (43%), Gaps = 21/162 (12%)

Query: 1   MQVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 59
           + +N +S  ++T   LP + + SKG+++ +SS  G +P    T YSA K  +D F   L 
Sbjct: 158 ININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLH 217

Query: 60  RELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEH------RGVPLQSQTAMFL 113
            E   + V V   +        A+    +R  T     PE       + V LQS+T  +L
Sbjct: 218 EEYRSKGVFVQSVLPYF----VATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYL 273

Query: 114 PPTVPGARTLTETPLRGWPQPKMKSSRQKS-------KTEKN 148
              + G+     + L  W   K+  +  KS       KT+KN
Sbjct: 274 IHALMGS---IISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN 312


>gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo
           sapiens]
          Length = 270

 Score = 37.7 bits (86), Expect = 0.005
 Identities = 18/51 (35%), Positives = 32/51 (62%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFAL 51
           +++N +    LT  ALP L  S+G+++ +SSL+G +  + + PY A K A+
Sbjct: 111 LELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAV 161


>gi|25282469 retinol dehydrogenase 10 [Homo sapiens]
          Length = 341

 Score = 37.7 bits (86), Expect = 0.005
 Identities = 32/122 (26%), Positives = 54/122 (44%), Gaps = 22/122 (18%)

Query: 1   MQVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 59
           M VN  ++   T   LP++ + + G +V V+S LG   T+    Y A+KF + GF  SL 
Sbjct: 166 MMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLS 225

Query: 60  RELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPE---HRGVPLQSQTAMFLPPT 116
            EL                  +A+  + ++++   P   +    RG  ++ +   FLPP 
Sbjct: 226 HEL------------------KAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPL 267

Query: 117 VP 118
            P
Sbjct: 268 KP 269


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.131    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,824,032
Number of Sequences: 37866
Number of extensions: 296895
Number of successful extensions: 1367
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1314
Number of HSP's gapped (non-prelim): 73
length of query: 181
length of database: 18,247,518
effective HSP length: 96
effective length of query: 85
effective length of database: 14,612,382
effective search space: 1242052470
effective search space used: 1242052470
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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