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Search of human proteins with 38373673
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38373673 synaptonemal complex protein 2 [Homo sapiens]
(1530 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38373673 synaptonemal complex protein 2 [Homo sapiens] 3037 0.0
gi|94400925 synaptonemal complex protein 2-like [Homo sapiens] 278 2e-74
gi|87299628 biorientation of chromosomes in cell division 1-like... 61 7e-09
gi|71061468 centromere protein E [Homo sapiens] 60 2e-08
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 58 8e-08
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 53 2e-06
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 53 3e-06
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 53 3e-06
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 50 2e-05
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 50 2e-05
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 50 2e-05
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 49 3e-05
gi|24233580 synaptonemal complex protein 3 [Homo sapiens] 49 4e-05
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 49 5e-05
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 49 5e-05
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 47 1e-04
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 46 2e-04
gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens] 46 2e-04
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 46 2e-04
gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens] 46 3e-04
gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens] 46 3e-04
gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens] 46 3e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens] 46 3e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 46 3e-04
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 45 7e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 44 0.001
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 44 0.001
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 44 0.001
gi|104526627 triadin [Homo sapiens] 44 0.002
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 42 0.003
>gi|38373673 synaptonemal complex protein 2 [Homo sapiens]
Length = 1530
Score = 3037 bits (7874), Expect = 0.0
Identities = 1530/1530 (100%), Positives = 1530/1530 (100%)
Query: 1 MPIRPDLQQLEKCIDDALRKNDFKPLKTLLQIDICEDVKIKCSKQFFHKVDNLICRELNK 60
MPIRPDLQQLEKCIDDALRKNDFKPLKTLLQIDICEDVKIKCSKQFFHKVDNLICRELNK
Sbjct: 1 MPIRPDLQQLEKCIDDALRKNDFKPLKTLLQIDICEDVKIKCSKQFFHKVDNLICRELNK 60
Query: 61 EDIHNVSAILVSVGRCGKNISVLGQAGLLTMIKQGLIQKMVAWFEKSKDIIQSQGNSKDE 120
EDIHNVSAILVSVGRCGKNISVLGQAGLLTMIKQGLIQKMVAWFEKSKDIIQSQGNSKDE
Sbjct: 61 EDIHNVSAILVSVGRCGKNISVLGQAGLLTMIKQGLIQKMVAWFEKSKDIIQSQGNSKDE 120
Query: 121 AVLNMIEDLVDLLLVIHDVSDEGKKQVVESFVPRICSLVIDSRVNICIQQEIIKKMNAML 180
AVLNMIEDLVDLLLVIHDVSDEGKKQVVESFVPRICSLVIDSRVNICIQQEIIKKMNAML
Sbjct: 121 AVLNMIEDLVDLLLVIHDVSDEGKKQVVESFVPRICSLVIDSRVNICIQQEIIKKMNAML 180
Query: 181 DKMPQDARKILSNQEMLILMSSMGERILDAGDYDLQVGIVEALCRMTTEKQRQELAHQWF 240
DKMPQDARKILSNQEMLILMSSMGERILDAGDYDLQVGIVEALCRMTTEKQRQELAHQWF
Sbjct: 181 DKMPQDARKILSNQEMLILMSSMGERILDAGDYDLQVGIVEALCRMTTEKQRQELAHQWF 240
Query: 241 SMDFIAKAFKRIKDSEFETDCRIFLNLVNGMLGDKRRVFTFPCLSAFLDKYELQIPSDEK 300
SMDFIAKAFKRIKDSEFETDCRIFLNLVNGMLGDKRRVFTFPCLSAFLDKYELQIPSDEK
Sbjct: 241 SMDFIAKAFKRIKDSEFETDCRIFLNLVNGMLGDKRRVFTFPCLSAFLDKYELQIPSDEK 300
Query: 301 LEEFWIDFNLGSQTLSFYIAGDNDDHQWEAVTVPEEKVQIYSIEVRESKKLLTIILKNTV 360
LEEFWIDFNLGSQTLSFYIAGDNDDHQWEAVTVPEEKVQIYSIEVRESKKLLTIILKNTV
Sbjct: 301 LEEFWIDFNLGSQTLSFYIAGDNDDHQWEAVTVPEEKVQIYSIEVRESKKLLTIILKNTV 360
Query: 361 KISKREGKELLLYFDASLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQI 420
KISKREGKELLLYFDASLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQI
Sbjct: 361 KISKREGKELLLYFDASLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQI 420
Query: 421 LVPESQISPVGEELVSLKEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEA 480
LVPESQISPVGEELVSLKEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEA
Sbjct: 421 LVPESQISPVGEELVSLKEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEA 480
Query: 481 SMIVSGADRYTMRSPVLFSNTSIPPRRRRIKPPLQMTSSAEKPSVSQTSENRVDNAASLK 540
SMIVSGADRYTMRSPVLFSNTSIPPRRRRIKPPLQMTSSAEKPSVSQTSENRVDNAASLK
Sbjct: 481 SMIVSGADRYTMRSPVLFSNTSIPPRRRRIKPPLQMTSSAEKPSVSQTSENRVDNAASLK 540
Query: 541 SRSSEGRHRRDNIDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILP 600
SRSSEGRHRRDNIDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILP
Sbjct: 541 SRSSEGRHRRDNIDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILP 600
Query: 601 GVLDNICGNKIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSIS 660
GVLDNICGNKIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSIS
Sbjct: 601 GVLDNICGNKIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSIS 660
Query: 661 DHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVES 720
DHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVES
Sbjct: 661 DHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVES 720
Query: 721 ETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNS 780
ETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNS
Sbjct: 721 ETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNS 780
Query: 781 WDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQ 840
WDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQ
Sbjct: 781 WDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQ 840
Query: 841 LSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACAD 900
LSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACAD
Sbjct: 841 LSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACAD 900
Query: 901 RSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSK 960
RSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSK
Sbjct: 901 RSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSK 960
Query: 961 PQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKATK 1020
PQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKATK
Sbjct: 961 PQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKATK 1020
Query: 1021 TKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQQKVFCAETEKELS 1080
TKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQQKVFCAETEKELS
Sbjct: 1021 TKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQQKVFCAETEKELS 1080
Query: 1081 KQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPY 1140
KQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPY
Sbjct: 1081 KQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPY 1140
Query: 1141 PKTSSLESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTIVNRK 1200
PKTSSLESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTIVNRK
Sbjct: 1141 PKTSSLESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTIVNRK 1200
Query: 1201 KISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQSKREESHLASSLSKSSE 1260
KISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQSKREESHLASSLSKSSE
Sbjct: 1201 KISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQSKREESHLASSLSKSSE 1260
Query: 1261 GREKTWFDMPCDATHVSGPTQHLSRKRIYIEDNLSNSNEVEMEEKGERRANLLPKKLCKI 1320
GREKTWFDMPCDATHVSGPTQHLSRKRIYIEDNLSNSNEVEMEEKGERRANLLPKKLCKI
Sbjct: 1261 GREKTWFDMPCDATHVSGPTQHLSRKRIYIEDNLSNSNEVEMEEKGERRANLLPKKLCKI 1320
Query: 1321 EDADHHIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMTYETYERLNSEFKRRNNIRHKM 1380
EDADHHIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMTYETYERLNSEFKRRNNIRHKM
Sbjct: 1321 EDADHHIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMTYETYERLNSEFKRRNNIRHKM 1380
Query: 1381 LSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIIIEELENFEKDSQSLKDLEKEFV 1440
LSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIIIEELENFEKDSQSLKDLEKEFV
Sbjct: 1381 LSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIIIEELENFEKDSQSLKDLEKEFV 1440
Query: 1441 DFWEKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCNTDSEETVFTSEMCLMKEDMKVLQDR 1500
DFWEKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCNTDSEETVFTSEMCLMKEDMKVLQDR
Sbjct: 1441 DFWEKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCNTDSEETVFTSEMCLMKEDMKVLQDR 1500
Query: 1501 LLKDMLEEELLNVRRELMSVFMSHERNANV 1530
LLKDMLEEELLNVRRELMSVFMSHERNANV
Sbjct: 1501 LLKDMLEEELLNVRRELMSVFMSHERNANV 1530
>gi|94400925 synaptonemal complex protein 2-like [Homo sapiens]
Length = 812
Score = 278 bits (712), Expect = 2e-74
Identities = 158/386 (40%), Positives = 240/386 (62%), Gaps = 10/386 (2%)
Query: 10 LEKCIDDALRKNDFKPLKTLLQIDICEDVKIKCSKQFFHKVDNLICRELNKEDIHNVSAI 69
L+ I DA F+ +K Q + K ++ +++D I +EL+K + +VS +
Sbjct: 27 LQSLITDAFHDKGFQKIKEYFQQKESHFPQ-KYNRLLLYRLDRSINKELDKNEFQSVSLL 85
Query: 70 LVSVGRCGKNISVLG-QAGLLTMIKQGLIQKMVAWFEKSKDIIQSQGNSKDEAVLNMIED 128
L +C + V G + +I+QGLI K+V+WFE++ I+ S+G + D +++ +IED
Sbjct: 86 L----KCIQRFLVDGLKEDEPLLIRQGLIPKLVSWFERTTGILTSEGLASDTSLICVIED 141
Query: 129 LVDLLLVIHDVSDEGKKQVVESFVPRICSLVIDSRVNICIQQEIIKKMNAMLDKMPQDAR 188
D L+I S EGK Q+++SF+ + LV + VN +QQE +K N +L +P++ R
Sbjct: 142 FFDTALIISRSSSEGKIQMLDSFLLSLGFLVTEKTVNHLLQQEGLKTFNCILHAVPREER 201
Query: 189 KILSNQE-MLILMSSMGERILDAGDYDLQVGIVEALCRMTTEKQRQELAHQWFSMDFIAK 247
K E M LM + +L GDYD QV I EALCR+T +K R EL H+WF + IA+
Sbjct: 202 KKFPLSEGMCHLMKDLARTLLTVGDYDQQVAISEALCRLTIKKSRDELVHKWFDDEVIAE 261
Query: 248 AFKRIKDSEFETDCRIFLNLVNGMLGDKRRVFTFPCLSAFLDKYELQIPSDEKLEEFWID 307
AFK IKD EFETD R FLN +N LGD+RRV++FPC++AF D++E++ P+DEKLE+FWID
Sbjct: 262 AFKEIKDREFETDSRRFLNHLNNRLGDQRRVYSFPCIAAFADEHEMRKPADEKLEKFWID 321
Query: 308 FNLGSQTLSFYIAGDNDDHQ-WEAVTVPEEKVQIYSIEVRESKKLLTIILKNTVKISKRE 366
FNLGSQ+++FYI DN ++ W++VT+P+E V +SI E K+ I LK + IS +E
Sbjct: 322 FNLGSQSVTFYI--DNAENTLWDSVTLPKEAVMNFSITETEKIKIFIIYLKKPMIISYKE 379
Query: 367 GKELLLYFDASLEITNVTQKIFGATK 392
++ ++FD I+ V+ + G K
Sbjct: 380 VMKIEIHFDLQFNISQVSIQALGEDK 405
Score = 61.6 bits (148), Expect = 6e-09
Identities = 93/408 (22%), Positives = 174/408 (42%), Gaps = 43/408 (10%)
Query: 1074 ETEKELSKQWKNSSLLKDAIRDNCL------DLSPRSLSGSPSSIEVTRCIEKITEKDFT 1127
E E E +++ N A D CL D S + G P+S + + DF
Sbjct: 434 ERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFP 493
Query: 1128 QDYDCITKSISPYPKTSSLESL--NSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFL 1185
Q + S Y K ES +S S + T K + K++ ++ + + L
Sbjct: 494 Q------QPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRI-L 546
Query: 1186 PRHTPTKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQ-S 1244
P P+ + + K + L+ E + + S +SE++F + + E+ Q +
Sbjct: 547 PVFPPSSGSG--HEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQDSFAFLTAEDSAQKT 604
Query: 1245 KREESHLASSLS--KSSEGREKTWF---DMPCDATHVSGPTQHLSRKRIYIEDNLSNSNE 1299
+ ++ H S LS K SE EK + ++T + ++L K I E + + S +
Sbjct: 605 ELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLEDKDIP-EGSFAKSQQ 663
Query: 1300 VEMEEKGERRANLLPKKLCKIEDADHHIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMT 1359
+EE+ A+ P + + + I S V + N +I
Sbjct: 664 SRLEEEV---ASGSPFSITEERELPEGISTSSLEVVPENLNGSAI--------------- 705
Query: 1360 YETYERLNSEFKRRNNIRHKMLSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIII 1419
T+E + KR+ +R++ F +++ K A L + +Q Q R+ KL++FQ +++
Sbjct: 706 LPTFENFTKKRKRKYELRYRKRP-FNSENAKKAPDCLIKLLNQMQLFRLNKLERFQNLVL 764
Query: 1420 EELENFEKDSQSLKDLEKEFVDFWEKIFQKFSAYQKSEQQRLHLLKTS 1467
+EL + ++D Q+L+ LEKE ++FW K ++ + R + +TS
Sbjct: 765 QELSSLKQDIQALEHLEKEVLEFWGKQSADLQSFCDLQVLRFNSTQTS 812
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 61.2 bits (147), Expect = 7e-09
Identities = 89/439 (20%), Positives = 174/439 (39%), Gaps = 61/439 (13%)
Query: 629 NQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVE 688
NQ AS + T + +++ +K+ S +D +++ KE+T DK +
Sbjct: 212 NQEASAARASTETSNAKTSERASKKLPSQPTTDTSTD--------KERTSEDMADKEKST 263
Query: 689 VCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKS-----VLLNKTIEESLIYRKKY 743
+ PK +E PVE + +LLNK +++ +K
Sbjct: 264 ADSGGEGLETAPK------SEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNK 317
Query: 744 ILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGKEFTNVAES 803
S D D N + + K EK+ S D+++ K +++K KE ES
Sbjct: 318 --STDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKE----VES 371
Query: 804 LISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTS 863
L K ++ T++ SLI+S T + V+S
Sbjct: 372 LKLPSEKNSNKAKTVEGTKE-DFSLIDSDVDG--------------------LTDITVSS 410
Query: 864 ECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRSIRLVGPRNHDELKSSVKTKDK 923
+D+ +F + ++ + ++E + T+ + ++ + + S KTK
Sbjct: 411 -VHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNK---TKTQTSDSSEGKTKSV 466
Query: 924 KIITNHQK---KNLFSDTETEYRCDDSKTDISWLREPKSKPQLIDYSRNKNVKNHKSGKS 980
+ H+ +SD++ E + + I+ +E + + I+ + + + K+ K+
Sbjct: 467 RHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKT 526
Query: 981 RSSLEKGQPSSKMTPSKNITKKMD------KTIPEGRIRLPRKATKTKKNYKDLSNSE-- 1032
+SS KGQ S + ++ TK ++ K + + R L +K +KK KD N E
Sbjct: 527 KSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEEN 586
Query: 1033 SECEQEFSHSFKENIPVKE 1051
S+ +Q++ KE + E
Sbjct: 587 SKKKQQYEEDSKETLKTSE 605
Score = 47.0 bits (110), Expect = 1e-04
Identities = 118/638 (18%), Positives = 256/638 (40%), Gaps = 95/638 (14%)
Query: 640 LNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKI----DKAEVEVCK--KH 693
L + + ++KK ++K S ++ +++ + K +Y+++ + +K +K ++ K KH
Sbjct: 566 LEKKVALSKK--RKKDSRNVEENSKK---KQQYEEDSKETLKTSEHCEKEKISSSKELKH 620
Query: 694 NQQQNHPKYSGQKNTE-------NAKQSDWPVESETTFKSVLLNKTIEESLIYR--KKYI 744
++ P ++ +E N +S E + + ++ + ++E R K+ +
Sbjct: 621 VHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQV 680
Query: 745 LSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGKEFTNVAESL 804
++ T K S KN + H K + T L S K+ K ++ +E T + L
Sbjct: 681 ERSEICTEEPQKQKSTLKN-EKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKL 739
Query: 805 ISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTSE 864
+ ++K K D + L +S K +E +QK+S + ++ +
Sbjct: 740 ----SVKHKYKGDCMHKTGDETELHSSEKGLKV-----EENIQKQSQQTKLSSDDKTERK 790
Query: 865 CPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRSIRLVGPRNHDELKSSVKTKDKK 924
+ ++ G D + I + ++ + RL + E KS ++ D K
Sbjct: 791 SKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSR-RSSDSK 849
Query: 925 IITNHQKKNLFS-----------DTETEYRCDDSKTDISWLREP-----KSKPQLIDYSR 968
I QK +L S ++ +E +CD T++ +P K K +
Sbjct: 850 I----QKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLE 905
Query: 969 NKNVKNHKS---GKS----RSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRL-----PR 1016
K V KS GK + L++G TP + K ++ E + + P
Sbjct: 906 EKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPF 965
Query: 1017 KATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTV------KLPKKQQKV 1070
+ T + + S+S +++ SH K +P+ +E S + KL +
Sbjct: 966 EETGVEPVLETASSSAHSTQKDSSHRAK--LPLAKEKYKSDKDSTSTRLERKLSDGHKSR 1023
Query: 1071 FCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDY 1130
+ K++ K+ +N S KD +D S G+ S +E +K++ +
Sbjct: 1024 SLKHSSKDIKKKDENKSDDKDGKE---VDSSHEKARGNSSLME-----KKLSRRLCENRR 1075
Query: 1131 DCITKSISPYPKTSSLESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTP 1190
+++ ++ + + +L++ SG +++ PK + L +P P
Sbjct: 1076 GSLSQEMAKGEEKLAANTLSTPSG--SSLQRPKKSGDMTL--------------IPEQEP 1119
Query: 1191 TKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEER 1228
+ ++ + + + TQ+ +N+NS D+ S + +++
Sbjct: 1120 MEIDSEPGVENVFEVSKTQDNRNNNSQQDIDSENMKQK 1157
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 59.7 bits (143), Expect = 2e-08
Identities = 165/934 (17%), Positives = 365/934 (39%), Gaps = 150/934 (16%)
Query: 676 QTDHIKIDKAEVEVCKKHNQQQNHPK-YSGQKNTENAKQSDWPVESETTFKSVLLNKTIE 734
+++++++ + E+ + Q +N + Y Q + Q D E ++ F + ++
Sbjct: 645 RSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLI 704
Query: 735 ESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKE--LTSELNSWDSKQKKMREKS 792
+ + K + + ++ D +K V+ + +E L SEL S S+ +++R++
Sbjct: 705 DGKV-PKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEI 763
Query: 793 KGKE-----FTNVAESLISQINKRY-----------KTKDDIKSTRKLKESLINSGFSNK 836
+ K T+ + L S++ + KTKDD+ +T+ +S + F N
Sbjct: 764 QDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKST-DQEFQNF 822
Query: 837 PVVQLSKEKVQK---KSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEFQAT 893
+ + E+ K + ++ VN++ E D + GA + QE Q
Sbjct: 823 KTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFD----SSLGALKTELSYKTQELQEK 878
Query: 894 AKEACADRSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISW 953
+E RL ++LK ++ +D + T ++K L ++ + + ++
Sbjct: 879 TREV----QERL---NEMEQLKEQLENRDSTLQTVEREKTLITE-----KLQQTLEEVKT 926
Query: 954 LREPKSKPQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIR 1013
L + K + + S +E+ Q S + + N+ + +
Sbjct: 927 LTQEKDDLKQLQESLQ--------------IERDQLKSDIHDTVNMNIDTQEQL------ 966
Query: 1014 LPRKATKTKKNYKDLSNS-ESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQQKVFC 1072
R A ++ K +++ N+ +S+ +E S + E + K V + KKQ
Sbjct: 967 --RNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDL--- 1021
Query: 1073 AETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDC 1132
+ KN+ L ++DN + R + S I+ ++++ E +
Sbjct: 1022 ---------EAKNTQTLTADVKDNEIIEQQRKIF---SLIQEKNELQQMLESVIAEKEQL 1069
Query: 1133 ITKSISPYPKTSSLESLNSNSGVGGTIKSPKN---NEKNFLCASES--CSPIPRPLFLPR 1187
T T +E+ +G +K + EKN E R +
Sbjct: 1070 KTDLKENIEMT--IENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEE 1127
Query: 1188 HTPTKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPH----------- 1236
KS + +++ V + ++ +++ + +E + E+ H
Sbjct: 1128 KLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQK 1187
Query: 1237 INENY--IQSKREESHLASSLSKSSEGREK--TWFDMPCDATHVSGPTQHLSRKRIYIED 1292
+NENY ++S +E + L KS E + +AT + + L I++++
Sbjct: 1188 LNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQ-TKEELKIAHIHLKE 1246
Query: 1293 NLSNSNEVE--MEEKGERRANL--LPKKLCKIEDADHHIHK----------MSESVSSLS 1338
+ +E+ + EK + N L K K+++ +H+ +SE+ +++
Sbjct: 1247 HQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMN 1306
Query: 1339 TNDFSIPWETWQNE--FAGIEMT--------YETYERLNSEFKRRNN---------IRHK 1379
+ T ++ A IEM E+ E + S K R+N ++H
Sbjct: 1307 ELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHD 1366
Query: 1380 MLSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIIIEELENFEKDSQSLKDLEKEF 1439
L ++ Q+ + + Q Q +K+ D I+ E+E F+ +L +E E
Sbjct: 1367 QLKEHIRETLAKIQE---SQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEM 1423
Query: 1440 VDFWEKIFQ-----KFSAYQKSEQQRLH--------LLKTSLAKSVFCNTDSEETVFTSE 1486
+ +++ + K A +K + QRL LK ++ + V + ++EE + +
Sbjct: 1424 LGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAH 1483
Query: 1487 MCLMKEDMKVLQDRLLKDMLEEELLNVRRELMSV 1520
CL +++ + + R+ E E+ ++++L ++
Sbjct: 1484 CCLKEQEETINELRVNLSEKETEISTIQKQLEAI 1517
Score = 49.3 bits (116), Expect = 3e-05
Identities = 148/825 (17%), Positives = 330/825 (40%), Gaps = 123/825 (14%)
Query: 674 KEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKTI 733
KE+ D + + E + K Q H + + ++A+ + +E+E + K LL +
Sbjct: 529 KEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREK- 587
Query: 734 EESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSK 793
E+ + ++YI S+ + D + S + + +E + D+K++ +S+
Sbjct: 588 EDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSE 647
Query: 794 GKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKSYRK 853
E + L + + ++DI+ L S K +Q+ EK + ++ +
Sbjct: 648 NLELKEKMKELATTYKQM---ENDIQ--------LYQSQLEAKKKMQVDLEKELQSAFNE 696
Query: 854 LKTTFVNVTSECPVNDVYNFNLNGADDPIIK---LGIQEFQATAKEACADRSIRLVGPRN 910
+ + + P + + N L G + K ++E +A +E ++ + P
Sbjct: 697 ITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSL-PSE 755
Query: 911 HDELKSSVKTKDKKI-ITNHQKKNLFSDT-ETEYRCDDSKTDISWLREPKSKPQLIDYSR 968
+ L+ ++ K +++ I +K LFS+ E R +I ++ + Q S
Sbjct: 756 VERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKST 815
Query: 969 NKNVKNHKS------GKSRSSLEKGQP-SSKMTPSKNITKKMDKTIPEGRIRLPRKATKT 1021
++ +N K+ K + LE+ + + ++ +K D ++ + L K +
Sbjct: 816 DQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQEL 875
Query: 1022 KKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQQKVFCAETEKELSK 1081
++ +++ +E EQ KE + EN S ++TV +++K E ++ +
Sbjct: 876 QEKTREVQERLNEMEQ-----LKEQL----ENRDSTLQTV----EREKTLITEKLQQTLE 922
Query: 1082 QWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPYP 1141
+ K + KD L S+++ R ++ + +D + +I
Sbjct: 923 EVKTLTQEKD------------DLKQLQESLQIER------DQLKSDIHDTVNMNIDTQE 964
Query: 1142 K-TSSLESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTIVNRK 1200
+ ++LESL + T+KS + E + R L + +T + ++
Sbjct: 965 QLRNALESLKQHQETINTLKSKISEE------------VSRNLHMEENTGETKDEF--QQ 1010
Query: 1201 KISSLVLTQETQNSNSY---SDVSSYSSEERFMEIESPHINENYIQSKRE---------E 1248
K+ + Q+ + N+ +DV E+ +I S +N +Q E +
Sbjct: 1011 KMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLK 1070
Query: 1249 SHLASSLSKSSEGREKTWF---DMPCDATHVSGPTQHLSRKRIYIEDNLSNSNE--VEME 1303
+ L ++ + E +E+ ++ V+ H +K E LS + + E+E
Sbjct: 1071 TDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKK----EGELSRTCDRLAEVE 1126
Query: 1304 EKGERRANLLPKKLCKIEDADHHIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMTYETY 1363
EK + ++ L +K ++ + + +M + ++ + E +NE E+T E
Sbjct: 1127 EKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEI---------ENLKNELKNKELTLEHM 1177
Query: 1364 ERLNSEFKRRNNIRHKMLSYFTTQ---------SWKTAQQHLRTMNHQSQDSRIKKLDKF 1414
E E ++ N ++ + T + S++T + HLR + + + ++ ++
Sbjct: 1178 ETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEEL 1237
Query: 1415 QFI---------IIEELEN--FEKDSQ--SLKDLEKEFVDFWEKI 1446
+ I+EL EK +Q + +DLEK E+I
Sbjct: 1238 KIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEI 1282
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 57.8 bits (138), Expect = 8e-08
Identities = 81/385 (21%), Positives = 159/385 (41%), Gaps = 62/385 (16%)
Query: 771 EKELTSELNSWDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLIN 830
+K+LT ++ + KQ K+++++ +E A + + R ++K++ K+
Sbjct: 518 QKDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHV--- 574
Query: 831 SGFSNKPVVQLSKEKVQKKSYRKLKT-TFVNVTSECPVNDVYNFNLNGADDPI-IKLGIQ 888
KP SKEKV K + +KT T +VT + + ++P +K +
Sbjct: 575 ----EKPPKVESKEKVMVKKDKPIKTETKPSVTEK---------EVPSKEEPSPVKAEVA 621
Query: 889 EFQAT--AKEACADRSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDD 946
E QAT +A +++++ ++ VK +DKK KK E +
Sbjct: 622 EKQATDVKPKAAKEKTVKK---------ETKVKPEDKKEEKEKPKK--------EVAKKE 664
Query: 947 SKTDISWLREPKSKPQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKT 1006
KT I +E K K + + K +K + + + ++K P ++ K + K+ K
Sbjct: 665 DKTPIK--KEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEV--KKEVKKEEKKE 720
Query: 1007 IPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKK 1066
+ + ++ K K+ K S SE ++ + K +P KEE++ PK+
Sbjct: 721 VKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAA--LKPKVPKKEESVKKDSVAAGKPKE 778
Query: 1067 QQKVFCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLS-----GSPSSIEVTRCIEKI 1121
+ K+ K + K+ K + + A+ + + + G +E R +
Sbjct: 779 KGKI------KVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSS 832
Query: 1122 TEKDFTQDYD-------CITKSISP 1139
E D T+D++ +TK I P
Sbjct: 833 PE-DLTKDFEELKAEEVDVTKDIKP 856
Score = 38.5 bits (88), Expect = 0.050
Identities = 52/239 (21%), Positives = 91/239 (38%), Gaps = 16/239 (6%)
Query: 972 VKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPE-GRIRLPRKATKTKKNYKDLSN 1030
VK K + S E +P++K PSK++ K+ + PE ++ K K + K +
Sbjct: 530 VKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVK 589
Query: 1031 SESECEQEFSHSF--------KENIPVKEENIHSRMKTVKLPKKQQKVFCAETE-KELSK 1081
+ + E S +E PVK E + VK ++K ET+ K K
Sbjct: 590 KDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDK 649
Query: 1082 QWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPYP 1141
+ + K+ + D +P P EV + ++K +K+ ++ K +P
Sbjct: 650 KEEKEKPKKEVAKKE--DKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPK 707
Query: 1142 KTSSLESLNSNSGVGGTIKSPKNNEKNF-LCASESCSPI---PRPLFLPRHTPTKSNTI 1196
+ V K PK K A +S +P+ +P L P K ++
Sbjct: 708 EVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESV 766
Score = 33.1 bits (74), Expect = 2.1
Identities = 47/227 (20%), Positives = 87/227 (38%), Gaps = 26/227 (11%)
Query: 648 KKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKN 707
K K S S+ + E T +V K++ E + KK + K S +
Sbjct: 546 KPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEK 605
Query: 708 TENAKQSDWPVESETTFKSV--LLNKTIEESLIYRKKYILSKDVN----------TATCD 755
+K+ PV++E K + K +E + ++ + +D D
Sbjct: 606 EVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKED 665
Query: 756 KNPSASKNVQSHRKAEKELTSELNSWDSKQ--KKMREKSKGKEF-TNVAESLISQINKRY 812
K P + + +KE+ E+ + K+ K++++++ KE V + ++ K
Sbjct: 666 KTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEE 725
Query: 813 K---------TKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKS 850
K KD KS+ L E+ + KP V +E V+K S
Sbjct: 726 KEPKKEIKKLPKDAKKSSTPLSEA--KKPAALKPKVPKKEESVKKDS 770
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 53.1 bits (126), Expect = 2e-06
Identities = 207/1078 (19%), Positives = 412/1078 (38%), Gaps = 169/1078 (15%)
Query: 524 SVSQTSENRVDNAASLKSRSSEGRHRRDNIDKHIKTAKCVENTENKNVEFPNQNFSELQD 583
++SQ S ++D A + + N+DK K N + E P ++D
Sbjct: 151 TISQQSAEKLDAACGIDKTENGTLFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKD 210
Query: 584 VIPDSQAAEKRDH--TILPGVLDNICGNKIHSKWACWTPVTNIELCNNQRASTSSGDTLN 641
DH T G +D++ ++ S+ + +T E + +A+ D+
Sbjct: 211 ----------SDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPP 260
Query: 642 QDIVINKKLTKQKSSSSISDHNS-------EG--TGKVKYKKEQTDHIKIDKAE--VEVC 690
V ++K +K++S D S EG +G V +K+ + D+ + +
Sbjct: 261 PGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 320
Query: 691 KKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKTIEESLIYRKKYILSKDVN 750
+ + Q S Q KQS W V I++KK L +N
Sbjct: 321 TEIKEGQQSGTVSPQ------KQSAWKV-------------------IFKKKVSL---LN 352
Query: 751 TATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGKEFTNVAESLISQINK 810
AT S V S ++ + TS+ DS E G + V+
Sbjct: 353 IATRITGGGKSGTVSSQKQPPSKATSD--KTDSALNIATEIKDGLQCGTVSS-------- 402
Query: 811 RYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLKT----TFVNVTSECP 866
+ + +K+T ++S+ N K + QK+ K T + +N+ +E
Sbjct: 403 --QKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIK 460
Query: 867 VNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRSIRLVGPRNHDELKSSVKTKDKK-- 924
+ + ++ P +K AT E + S+ ++ D KS + KK
Sbjct: 461 DGE-KSETVSSQKQPALK-------ATTDE---EDSVSIIATEIKDGEKSGTVSSRKKPA 509
Query: 925 IITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSKPQLIDYSRNKNV-KNHKSG-KSRS 982
+ +K+ FS+ E + + +S + P K + ++ + K G KSR+
Sbjct: 510 LKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRT 569
Query: 983 SLEKGQPSSKMTPSK-----NIT---KKMDKTIPEGRIRLPR-KATKTKKNYKDLSNSES 1033
+ P K T + NI K +KT + P KAT K+N +E+
Sbjct: 570 VSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATET 629
Query: 1034 ECEQEFSHSFKENIPVKEENIHSRMKTVKLP---KKQQKVFCAETEKELSKQWKNSSLLK 1090
+ EQ + P + + +P K Q+ ++K+L+ WK +S+ K
Sbjct: 630 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLA--WKATSVKK 687
Query: 1091 DAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPYPKTSSLESLN 1150
D++ + ++ + G+ SS EKD + I + I K+ ++
Sbjct: 688 DSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSN---IAREIKDGEKSGTVSP-- 742
Query: 1151 SNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTIVNRKKI-SSLVLTQ 1209
I K + N A+ P + PT TI N+ + ++ +
Sbjct: 743 QKQSAQKVIFKKKVSLLNI--ATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMK 800
Query: 1210 ETQNSNSYS---DVSSYSSEERFMEIES--PHINENYIQSKREESHLASSLSKSSEGREK 1264
+ Q S +++S ++R E E+ P + +N I S+ + + S SE +
Sbjct: 801 DVQTSTPAEQDLEMASEGEQKRLEEYENNQPQV-KNQIHSRDDLDDIIQSSQTVSEDGDS 859
Query: 1265 ------------TWFDMPC-DATHV--SGPTQHLSRKRIYIEDNLSNSNEVEMEEKGERR 1309
+M C D H+ T L ++ ++DN V++ K + +
Sbjct: 860 LCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKI-RKLKNK 918
Query: 1310 ANLLPKKLCKIEDADHHI-HKMSESVSSLSTNDFSIPWETWQNEFAGIEMTYETYERLNS 1368
A++L K+L + E+ + H+ E L + F+I E + E L+
Sbjct: 919 ASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQE---------KKKRRNVEELHQ 969
Query: 1369 EFKRRNNIRHKM------LSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIIIEE- 1421
+ + + I + ++ + K+A+ L+T + S +++ + D+ + ++ E
Sbjct: 970 KVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNS--NQVSETDEKEDLLHENR 1027
Query: 1422 -------LENFEKDSQSLKDLEKEFVDFWEKIFQKFSAYQKSEQQRLHLLKTSLAKSVFC 1474
EKD+ ++LEK+++ +E + +K QK+ ++ + +LA+++ C
Sbjct: 1028 LMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRN----EETLAETIAC 1083
Query: 1475 NTDSEETVFTSEMCLMKEDMKVLQDRLLK-----DMLEEELLNVRRELMSVFMSHERN 1527
++ ++ + ++ L+ +L K LE E+ + R L + H+++
Sbjct: 1084 --------YSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQS 1133
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 52.8 bits (125), Expect = 3e-06
Identities = 171/840 (20%), Positives = 298/840 (35%), Gaps = 142/840 (16%)
Query: 438 KEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSP-- 495
K K + + S+ N + + E T + K ++ S D +R
Sbjct: 898 KHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPM 957
Query: 496 ----VLFSNTSIPPRRRRIKPPLQMTSSAEKPSVSQTS--ENRVDNAASLKSRSSEGRHR 549
+ F + S +R R KP + + K S S EN V A + + R R
Sbjct: 958 DAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERER 1017
Query: 550 RDNIDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDNICGN 609
+ IK AK E + N + S ++ ++D I
Sbjct: 1018 SPRSEPPIKKAK-EETPKTDNTK---------------SSSSSQKDEKITG------TPR 1055
Query: 610 KIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGK 669
K HSK A T + S +D+ K TK++ + ++ N K
Sbjct: 1056 KAHSKSAKEHQETKPVKEEKVKKDYS------KDVKSEKLTTKEEKAKKPNEKNKPLDNK 1109
Query: 670 VKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLL 729
+ +K +T+ +DK + + + K S + TE K S T K +
Sbjct: 1110 GEKRKRKTEEKGVDK---------DFESSSMKISKLEVTEIVKPSPKRKMEPDTEK---M 1157
Query: 730 NKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMR 789
++T E+ I +N T K +++N+ + KE + +L S SK K +
Sbjct: 1158 DRTPEKDKISLSAPAKKIKLNRET-GKKIGSTENISN----TKEPSEKLESTSSKVK--Q 1210
Query: 790 EKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKK 849
EK KGK R K S+ L + S P V+ S+EK K
Sbjct: 1211 EKVKGK--------------VRRKVTGTEGSSSTLVDYTSTSSTGGSP-VRKSEEKTDTK 1255
Query: 850 SYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGI-------QEFQATAKEACADRS 902
+KT + + N N A+D II + + +F++ ++ + +
Sbjct: 1256 R-TVIKT----------MEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQP 1304
Query: 903 IRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSKPQ 962
I VG + +V TK I+ +K++ EP K Q
Sbjct: 1305 ISSVG--KPASVIKNVSTKPSNIVKYPEKES----------------------EPSEKIQ 1340
Query: 963 LIDYSRNKNVKNH--KSGKSRSSLEKGQPSSK---MTPSKNITKKMDKTIPEGRIRLPRK 1017
+ + H KS K+ +S EKG+ + + +N K+ + T PE L R
Sbjct: 1341 KFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDR- 1399
Query: 1018 ATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQQKVFCAETEK 1077
+ N+K LS S E H K+ + KT ++ + +
Sbjct: 1400 -LNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKN 1458
Query: 1078 ELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSI 1137
EL+++ + S KD S SG + R + K D + ++
Sbjct: 1459 ELTRRKDSPSRNKD------------SASGQKNKPREERDLPKKGTGDSKKSNSSPSRDR 1506
Query: 1138 SPYPKTSSLESLNSNSGVGGTIKSP-KNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTI 1196
P+ ++ ++ N K+P K+ EK+ L A + L + P T
Sbjct: 1507 KPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPP---ETQ 1563
Query: 1197 VNRKKISSLV-------LTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQSKREES 1249
V +++I+ + Q + +S SD++ + E F + +E+ + K EES
Sbjct: 1564 VEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEES 1623
Score = 43.1 bits (100), Expect = 0.002
Identities = 93/443 (20%), Positives = 173/443 (39%), Gaps = 72/443 (16%)
Query: 449 KPSKYIKNSDKG---NRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNTSIPP 505
K SK +S+KG +R+ S LEK P KRK S S DR + F + S
Sbjct: 1356 KSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGN--FKSLSQSS 1413
Query: 506 RRRRIKPPLQMTSSAEKPSVSQTSENRVD------NAASLKSRSSEGRHRRDNIDKHIKT 559
+ R T ++ + + + D +++ + +E R+D+ ++ +
Sbjct: 1414 KEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDS 1473
Query: 560 AKCVENTENKNVEFPNQ--------NFSELQDVIPDSQAA---EKRDHTILPGVLDNICG 608
A +N + + P + N S +D P A KR + V N C
Sbjct: 1474 ASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCK 1533
Query: 609 NKIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTG 668
++ +E NN+ SSG+ L + I Q I+ + T
Sbjct: 1534 DREKHV---------LEARNNKE---SSGNKL---LYILNPPETQVEKEQITGQIDKSTV 1578
Query: 669 KVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVL 728
K K + + + D + ++ ++ P Y+ E+ +S+ V+ E + S
Sbjct: 1579 KPKPQLSHSSRLSSD-----LTRETDEAAFEPDYN-----ESDSESNVSVKEEES--SGN 1626
Query: 729 LNKTIEESLIYRKKYIL----------SKDVNTATCDKNPSASKNVQ-SHRKAEKELTSE 777
++K +++ ++ + K L S++ + ++ +PS S + S ++ S
Sbjct: 1627 ISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASS 1686
Query: 778 LNSWDS-KQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNK 836
S DS K+KK +EK K K+ K K K + +L++S + K
Sbjct: 1687 AESQDSKKKKKKKEKKKHKKH-----------KKHKKHKKHAGTEVELEKSQKHKHKKKK 1735
Query: 837 PVVQLSKEKVQKKSYRKLKTTFV 859
KEK ++K +K+K+ V
Sbjct: 1736 SKKNKDKEKEKEKDDQKVKSVTV 1758
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 52.8 bits (125), Expect = 3e-06
Identities = 171/840 (20%), Positives = 298/840 (35%), Gaps = 142/840 (16%)
Query: 438 KEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSP-- 495
K K + + S+ N + + E T + K ++ S D +R
Sbjct: 932 KHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPM 991
Query: 496 ----VLFSNTSIPPRRRRIKPPLQMTSSAEKPSVSQTS--ENRVDNAASLKSRSSEGRHR 549
+ F + S +R R KP + + K S S EN V A + + R R
Sbjct: 992 DAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERER 1051
Query: 550 RDNIDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDNICGN 609
+ IK AK E + N + S ++ ++D I
Sbjct: 1052 SPRSEPPIKKAK-EETPKTDNTK---------------SSSSSQKDEKITG------TPR 1089
Query: 610 KIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGK 669
K HSK A T + S +D+ K TK++ + ++ N K
Sbjct: 1090 KAHSKSAKEHQETKPVKEEKVKKDYS------KDVKSEKLTTKEEKAKKPNEKNKPLDNK 1143
Query: 670 VKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLL 729
+ +K +T+ +DK + + + K S + TE K S T K +
Sbjct: 1144 GEKRKRKTEEKGVDK---------DFESSSMKISKLEVTEIVKPSPKRKMEPDTEK---M 1191
Query: 730 NKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMR 789
++T E+ I +N T K +++N+ + KE + +L S SK K +
Sbjct: 1192 DRTPEKDKISLSAPAKKIKLNRET-GKKIGSTENISN----TKEPSEKLESTSSKVK--Q 1244
Query: 790 EKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKK 849
EK KGK R K S+ L + S P V+ S+EK K
Sbjct: 1245 EKVKGK--------------VRRKVTGTEGSSSTLVDYTSTSSTGGSP-VRKSEEKTDTK 1289
Query: 850 SYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGI-------QEFQATAKEACADRS 902
+KT + + N N A+D II + + +F++ ++ + +
Sbjct: 1290 R-TVIKT----------MEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQP 1338
Query: 903 IRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSKPQ 962
I VG + +V TK I+ +K++ EP K Q
Sbjct: 1339 ISSVG--KPASVIKNVSTKPSNIVKYPEKES----------------------EPSEKIQ 1374
Query: 963 LIDYSRNKNVKNH--KSGKSRSSLEKGQPSSK---MTPSKNITKKMDKTIPEGRIRLPRK 1017
+ + H KS K+ +S EKG+ + + +N K+ + T PE L R
Sbjct: 1375 KFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDR- 1433
Query: 1018 ATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQQKVFCAETEK 1077
+ N+K LS S E H K+ + KT ++ + +
Sbjct: 1434 -LNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKN 1492
Query: 1078 ELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSI 1137
EL+++ + S KD S SG + R + K D + ++
Sbjct: 1493 ELTRRKDSPSRNKD------------SASGQKNKPREERDLPKKGTGDSKKSNSSPSRDR 1540
Query: 1138 SPYPKTSSLESLNSNSGVGGTIKSP-KNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTI 1196
P+ ++ ++ N K+P K+ EK+ L A + L + P T
Sbjct: 1541 KPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPP---ETQ 1597
Query: 1197 VNRKKISSLV-------LTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQSKREES 1249
V +++I+ + Q + +S SD++ + E F + +E+ + K EES
Sbjct: 1598 VEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEES 1657
Score = 43.1 bits (100), Expect = 0.002
Identities = 93/443 (20%), Positives = 173/443 (39%), Gaps = 72/443 (16%)
Query: 449 KPSKYIKNSDKG---NRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNTSIPP 505
K SK +S+KG +R+ S LEK P KRK S S DR + F + S
Sbjct: 1390 KSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGN--FKSLSQSS 1447
Query: 506 RRRRIKPPLQMTSSAEKPSVSQTSENRVD------NAASLKSRSSEGRHRRDNIDKHIKT 559
+ R T ++ + + + D +++ + +E R+D+ ++ +
Sbjct: 1448 KEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDS 1507
Query: 560 AKCVENTENKNVEFPNQ--------NFSELQDVIPDSQAA---EKRDHTILPGVLDNICG 608
A +N + + P + N S +D P A KR + V N C
Sbjct: 1508 ASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCK 1567
Query: 609 NKIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTG 668
++ +E NN+ SSG+ L + I Q I+ + T
Sbjct: 1568 DREKHV---------LEARNNKE---SSGNKL---LYILNPPETQVEKEQITGQIDKSTV 1612
Query: 669 KVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVL 728
K K + + + D + ++ ++ P Y+ E+ +S+ V+ E + S
Sbjct: 1613 KPKPQLSHSSRLSSD-----LTRETDEAAFEPDYN-----ESDSESNVSVKEEES--SGN 1660
Query: 729 LNKTIEESLIYRKKYIL----------SKDVNTATCDKNPSASKNVQ-SHRKAEKELTSE 777
++K +++ ++ + K L S++ + ++ +PS S + S ++ S
Sbjct: 1661 ISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASS 1720
Query: 778 LNSWDS-KQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNK 836
S DS K+KK +EK K K+ K K K + +L++S + K
Sbjct: 1721 AESQDSKKKKKKKEKKKHKKH-----------KKHKKHKKHAGTEVELEKSQKHKHKKKK 1769
Query: 837 PVVQLSKEKVQKKSYRKLKTTFV 859
KEK ++K +K+K+ V
Sbjct: 1770 SKKNKDKEKEKEKDDQKVKSVTV 1792
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 50.1 bits (118), Expect = 2e-05
Identities = 101/452 (22%), Positives = 172/452 (38%), Gaps = 75/452 (16%)
Query: 716 WP-----VESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASK------NV 764
WP +T F+ + +KT + Y+K SKD T K S K N
Sbjct: 87 WPPIYTAAREQTPFRHLYTSKTHLKKAEYKK----SKDEKGGTPLKKDSKKKGGSYATNP 142
Query: 765 QSHRKAEKELTSELNSWD------SKQKKMREKSKGKEFTNVAESLISQINKRYKTKD-- 816
+S + E E T N D S + + +KSK TN ++K KD
Sbjct: 143 ESKQIVE-EKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKK 201
Query: 817 DIKSTRKL-----------KESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTSEC 865
D K+++K K+ L S SN P+ ++ E + L V + +
Sbjct: 202 DSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLML----VGQSDDE 257
Query: 866 PVN-DVY--NFNLNGADDPIIKLGIQEFQATAKEACADRSIRLVGPRNHDELKSSVKTKD 922
+N D + N++ N + + +K + T K A +S + D K S K K
Sbjct: 258 SINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNA--KKSSDAESEDSKDAKKDSKKVK- 314
Query: 923 KKIITNHQKKNLFSDTE-TEYRCDDSKTDISWLREPKSKPQLIDYSRNKNVKNHKSGKSR 981
K + + +KK++ DTE T+ DSK + ++ K K ++ K+ K
Sbjct: 315 KNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKK-----LKKDDKKKDTKKYPES 369
Query: 982 SSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKATKTKKNYKDLS----NSESECEQ 1037
+ E G S+N+ +KA+K KD +++SE E
Sbjct: 370 TDTESGDAKDARNDSRNL----------------KKASKNDDKKKDAKKITFSTDSESEL 413
Query: 1038 EFSHSFKENIPVKEENIHSRMKTVKLPKKQQKVFCAETEKELSKQWKNSSLLKDAIRDNC 1097
E S K+ K+++ K+VK ++ K SK+ K K +D+
Sbjct: 414 ESKESQKDEKKDKKDSKTDNKKSVK--NDEESTDADSEPKGDSKKGKKDE--KKGKKDSK 469
Query: 1098 LDLSPRSLSGSPSSIEVTRCIEKITEKDFTQD 1129
D + + S E+ +E +K +++
Sbjct: 470 KDDKKKDAKKNAESTEMESDLELKKDKKHSKE 501
Score = 36.6 bits (83), Expect = 0.19
Identities = 123/614 (20%), Positives = 227/614 (36%), Gaps = 87/614 (14%)
Query: 440 KSKSPKEFA----KPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSP 495
KS + K FA KP + N DK SQ+ T KRK+ E R++ R
Sbjct: 26 KSWNQKHFALTFPKPLQRGTN-DKSRPLKSQITVTRHDKRKLEEGQKPAHKWIRHSFRKI 84
Query: 496 VLFSNTSIPPRRRRIKPPLQMTSSAEKPSVS-QTSENRVDNAASLKSRSSEGRHRRDNID 554
+ + PP+ + + P TS+ + A KS+ +G D
Sbjct: 85 LQW-------------PPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKK-D 130
Query: 555 KHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDNICGNKIHSK 614
K N E+K + V ++ + D T L +N K S
Sbjct: 131 SKKKGGSYATNPESKQI------------VEEKTKRQNEADKTPLKSSHENEQSKKSKS- 177
Query: 615 WACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKK 674
+ TN E +Q + T S + +D KK +K ++ +++ K K+
Sbjct: 178 ----SSETNPE---SQNSKTVSKNCSQKD----KKDSKNSKKTNTEFLHTKNNPKKDLKR 226
Query: 675 EQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVE-SETTFKSVLLNKTI 733
+T + I E+C +++ + GQ + E+ W S+ K+ L T
Sbjct: 227 SKTSNDPIS----EICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTK 282
Query: 734 EESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKEL--------TSELNSWDSK- 784
+K S D + SK V+ + K + + +++ S DSK
Sbjct: 283 YTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKD 342
Query: 785 --------QKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKL------KESLIN 830
+KK+++ K K+ ES ++ ++D ++ +K K+
Sbjct: 343 ERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKK 402
Query: 831 SGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEF 890
FS +L ++ QK + K + + + ND + + + K G ++
Sbjct: 403 ITFSTDSESELESKESQKDEKKDKKDSKTD-NKKSVKNDEESTDADSEPKGDSKKGKKDE 461
Query: 891 QATAKEACADRSIRLVGPRNHD--ELKSSVK-TKDKKIITNHQKKNLFSDTETEYRCDDS 947
+ K++ D + +N + E++S ++ KDKK + +KK D + + R D
Sbjct: 462 KKGKKDSKKDDK-KKDAKKNAESTEMESDLELKKDKK--HSKEKKGSKKDIKKDARKDTE 518
Query: 948 KTDISWLREPKSKPQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPS--KNITKKMDK 1005
TD + K+ + + +K + +S SL K K+ S + KM+
Sbjct: 519 STDAEFDESSKT-----GFKTSTKIKGSDT-ESEESLYKPGAKKKIDESDGTSANSKMEG 572
Query: 1006 TIPEGRIRLPRKAT 1019
+ R+ K T
Sbjct: 573 LESKRGFRMSSKKT 586
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 49.7 bits (117), Expect = 2e-05
Identities = 158/841 (18%), Positives = 304/841 (36%), Gaps = 88/841 (10%)
Query: 511 KPPLQMTSSAEKPS----VSQTSENRVDNAASLKSRSS---EGRHRRDNIDKHIKTAKCV 563
+ P T+ +P+ V+ S+ + K + S + +R++ D I K
Sbjct: 617 RSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPN 676
Query: 564 ENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDNICGNKIHSKWACWTPVTN 623
+ ++K E +QN S+ +++ + + H+ N + + T
Sbjct: 677 KLPKSKQSETVDQN-SDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGK 735
Query: 624 IELCNNQRASTSSGDTLN-------QDIVINKKLTKQKSSSSISDHNSEGT-------GK 669
+ +R S++SG + + +I+KK + +S SS D E G
Sbjct: 736 DDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGA 795
Query: 670 VKYKKEQTDHIK-IDKAEVEVCKKH---NQQQNHPKYSGQKNTENAKQSDWPVESETTFK 725
+ K++ + K D +E E K NQ + K S + ++++A++ + TF
Sbjct: 796 ARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERK----QERETFS 851
Query: 726 SVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQ 785
S + +++ + + K +A+ D S QS E +E
Sbjct: 852 SAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHL 911
Query: 786 KKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRK-LKESLINSGFSNKPVVQLSKE 844
K K +++AE + + ++DD K ++K +E S F K + +
Sbjct: 912 KTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQY 971
Query: 845 KVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRSIR 904
+ KL + + N +G I++ + K+ +D + +
Sbjct: 972 ESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK---SKKIRDKTSKKKDELSDYAEK 1028
Query: 905 LVGPRNHDELKSSVKTKDKKIITNHQKKN---LFSDTETEYRCDDSKTDISWLREPKSKP 961
G D SS K K +KK L + C S T+ ++E
Sbjct: 1029 STG--KGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNS 1086
Query: 962 -----------QLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEG 1010
+ + S +N K +SG S S E+ +K + +KK + E
Sbjct: 1087 SDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEK 1146
Query: 1011 RIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQQKV 1070
+ R +TK +K S+S S+ E + +S E + + T L
Sbjct: 1147 KRNSLRTSTK-RKQADITSSSSSDIEDDDQNSIGEG---SSDEQKIKPVTENLVLSSHTG 1202
Query: 1071 FCAET-EKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQD 1129
FC + ++ LSK + + D+ D P + +E + E + D
Sbjct: 1203 FCQSSGDEALSKS------VPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD 1256
Query: 1130 YDCITKSISPYPKTSSLESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHT 1189
P N + K+ N+E + + ES P R L RH
Sbjct: 1257 --------EPEEGKKRTGKQNEENPGDEEAKNQVNSESD-SDSEESKKPRYRHRLL-RHK 1306
Query: 1190 PTKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQSKREES 1249
T S+ +K + +E + N VSS SE+ + + ++E +S+ E+
Sbjct: 1307 LTVSDGESGEEKKTKPKEHKEVKGRNR-RKVSSEDSED--SDFQESGVSEEVSESEDEQR 1363
Query: 1250 HLASSLSKSS-EGREKTWFDMPCDATHVSGPTQHLSRKRIYIEDNLSNSNEVEMEEKGER 1308
S K+ E ++++ Q R+RI ++++ S+ N+ EE+ E
Sbjct: 1364 PRTRSAKKAELEENQRSY-------------KQKKKRRRIKVQEDSSSENKSNSEEEEEE 1410
Query: 1309 R 1309
+
Sbjct: 1411 K 1411
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 49.7 bits (117), Expect = 2e-05
Identities = 158/841 (18%), Positives = 304/841 (36%), Gaps = 88/841 (10%)
Query: 511 KPPLQMTSSAEKPS----VSQTSENRVDNAASLKSRSS---EGRHRRDNIDKHIKTAKCV 563
+ P T+ +P+ V+ S+ + K + S + +R++ D I K
Sbjct: 655 RSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPN 714
Query: 564 ENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDNICGNKIHSKWACWTPVTN 623
+ ++K E +QN S+ +++ + + H+ N + + T
Sbjct: 715 KLPKSKQSETVDQN-SDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGK 773
Query: 624 IELCNNQRASTSSGDTLN-------QDIVINKKLTKQKSSSSISDHNSEGT-------GK 669
+ +R S++SG + + +I+KK + +S SS D E G
Sbjct: 774 DDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGA 833
Query: 670 VKYKKEQTDHIK-IDKAEVEVCKKH---NQQQNHPKYSGQKNTENAKQSDWPVESETTFK 725
+ K++ + K D +E E K NQ + K S + ++++A++ + TF
Sbjct: 834 ARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERK----QERETFS 889
Query: 726 SVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQ 785
S + +++ + + K +A+ D S QS E +E
Sbjct: 890 SAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHL 949
Query: 786 KKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRK-LKESLINSGFSNKPVVQLSKE 844
K K +++AE + + ++DD K ++K +E S F K + +
Sbjct: 950 KTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQY 1009
Query: 845 KVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRSIR 904
+ KL + + N +G I++ + K+ +D + +
Sbjct: 1010 ESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK---SKKIRDKTSKKKDELSDYAEK 1066
Query: 905 LVGPRNHDELKSSVKTKDKKIITNHQKKN---LFSDTETEYRCDDSKTDISWLREPKSKP 961
G D SS K K +KK L + C S T+ ++E
Sbjct: 1067 STG--KGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNS 1124
Query: 962 -----------QLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEG 1010
+ + S +N K +SG S S E+ +K + +KK + E
Sbjct: 1125 SDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEK 1184
Query: 1011 RIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQQKV 1070
+ R +TK +K S+S S+ E + +S E + + T L
Sbjct: 1185 KRNSLRTSTK-RKQADITSSSSSDIEDDDQNSIGEG---SSDEQKIKPVTENLVLSSHTG 1240
Query: 1071 FCAET-EKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQD 1129
FC + ++ LSK + + D+ D P + +E + E + D
Sbjct: 1241 FCQSSGDEALSKS------VPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD 1294
Query: 1130 YDCITKSISPYPKTSSLESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHT 1189
P N + K+ N+E + + ES P R L RH
Sbjct: 1295 --------EPEEGKKRTGKQNEENPGDEEAKNQVNSESD-SDSEESKKPRYRHRLL-RHK 1344
Query: 1190 PTKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQSKREES 1249
T S+ +K + +E + N VSS SE+ + + ++E +S+ E+
Sbjct: 1345 LTVSDGESGEEKKTKPKEHKEVKGRNR-RKVSSEDSED--SDFQESGVSEEVSESEDEQR 1401
Query: 1250 HLASSLSKSS-EGREKTWFDMPCDATHVSGPTQHLSRKRIYIEDNLSNSNEVEMEEKGER 1308
S K+ E ++++ Q R+RI ++++ S+ N+ EE+ E
Sbjct: 1402 PRTRSAKKAELEENQRSY-------------KQKKKRRRIKVQEDSSSENKSNSEEEEEE 1448
Query: 1309 R 1309
+
Sbjct: 1449 K 1449
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 49.3 bits (116), Expect = 3e-05
Identities = 86/403 (21%), Positives = 156/403 (38%), Gaps = 60/403 (14%)
Query: 680 IKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKTIEESLIY 739
IK DK+E+ K++ Q++ + +K T++ S+ P K V +K+ +
Sbjct: 381 IKGDKSELNEIKEN--QRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDI 438
Query: 740 RKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGKEFTN 799
R+ + S S++ + KE S+ N +++K+MR +SKG++ N
Sbjct: 439 RRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNR--NEEKRMRSRSKGRDHEN 496
Query: 800 VAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFV 859
V E + K KD +S K K + S SN+ SKEK ++ R
Sbjct: 497 VKE---KEKQSDSKGKDQERSRSKEKSKQLESK-SNEHDHSKSKEKDRRAQSR------- 545
Query: 860 NVTSECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRS-IRLVGPRNHDELKSSV 918
+ EC + G + + +E R R V R HD +S
Sbjct: 546 --SRECDITK----------------GKHSYNSRTRERSRSRDRSRRVRSRTHDRDRS-- 585
Query: 919 KTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSKPQLIDYSRNKNVKNHKSG 978
+ K E EYR + S RE ++ P SR+K+ + +
Sbjct: 586 -----------RSKEYHRYREQEYR----RRGRSRSRERRTPP---GRSRSKDRRRRRRD 627
Query: 979 KSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQE 1038
S E+ Q +K +K + E R +K++ + ++ E + +++
Sbjct: 628 SRSSEREESQSRNKDKYRNQESKSSHR--KENSESEKRMYSKSRDHNSSNNSREKKADRD 685
Query: 1039 FSHSFKENIPVKEENIHSRMKTVKLPKKQQKVFCAETEKELSK 1081
S K +K+ + + +K+ L K+ + + EKE K
Sbjct: 686 QSPFSK----IKQSSQDNELKSSMLKNKEDEKIRSSVEKENQK 724
Score = 37.7 bits (86), Expect = 0.086
Identities = 52/270 (19%), Positives = 101/270 (37%), Gaps = 26/270 (9%)
Query: 647 NKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQK 706
+K K KS S HN +++ + + DH + + E + K Q+ K
Sbjct: 462 SKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSK 521
Query: 707 NTEN---------AKQSDWPVESE------TTFKSVLLNKTIEESLIYRKKYILSKDVNT 751
E+ +K+ D +S T K ++T E S + S+ V +
Sbjct: 522 QLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERS----RSRDRSRRVRS 577
Query: 752 ATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGK------EFTNVAESLI 805
T D++ S SK +R+ E S + + R +SK + ++ E
Sbjct: 578 RTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQ 637
Query: 806 SQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTSEC 865
S+ +Y+ ++ S RK +S S +KK+ R ++ F +
Sbjct: 638 SRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRD-QSPFSKIKQSS 696
Query: 866 PVNDVYNFNLNGADDPIIKLGIQEFQATAK 895
N++ + L +D I+ +++ +K
Sbjct: 697 QDNELKSSMLKNKEDEKIRSSVEKENQKSK 726
Score = 32.3 bits (72), Expect = 3.6
Identities = 34/131 (25%), Positives = 59/131 (45%), Gaps = 9/131 (6%)
Query: 957 PKSKPQLIDYSRNKNVKNHKSGKSRS-SLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLP 1015
PKSK + + R+K+ + S S S S Q SS + S++ T++ K + +
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238
Query: 1016 RK-------ATKTKKNYKDLSNSES-ECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQ 1067
RK K+KK+ S +E+ E + + + +E P+ E R K +K+
Sbjct: 239 RKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKE 298
Query: 1068 QKVFCAETEKE 1078
+K E E+E
Sbjct: 299 RKNRERERERE 309
>gi|24233580 synaptonemal complex protein 3 [Homo sapiens]
Length = 236
Score = 48.9 bits (115), Expect = 4e-05
Identities = 31/147 (21%), Positives = 70/147 (47%), Gaps = 3/147 (2%)
Query: 1377 RHKMLSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIIIEELENFEKDSQSLKDLE 1436
+ K L +T S KT+ Q + + QD R K ++ + + ++ D Q ++ E
Sbjct: 88 KRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQE 147
Query: 1437 KEFVDFW---EKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCNTDSEETVFTSEMCLMKED 1493
++ ++ + +KI Q+ Q + + L KS+ + + + T K++
Sbjct: 148 EKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKE 207
Query: 1494 MKVLQDRLLKDMLEEELLNVRRELMSV 1520
M +LQ +++ + ++E+ +VR+ L S+
Sbjct: 208 MAMLQKKIMMETQQQEIASVRKSLQSM 234
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 48.5 bits (114), Expect = 5e-05
Identities = 137/687 (19%), Positives = 266/687 (38%), Gaps = 77/687 (11%)
Query: 647 NKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQK 706
N+ K K + + + +++ K + +++K A+ ++H Q ++ + QK
Sbjct: 628 NEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLE---QK 684
Query: 707 NTENAKQSDWPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCD-KNPSASKNV- 764
+ E K+ +E T K+ L K IE+ +Y +L + + T + KN V
Sbjct: 685 SGELGKKI-----TELTLKNQTLQKEIEK--VYLDNKLLKEQAHNLTIEMKNHYVPLKVS 737
Query: 765 QSHRKAEKELTSELNS--WDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTR 822
+ +K+ + +LN D QK +K + ++ +SL +++
Sbjct: 738 EDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSR------------ 785
Query: 823 KLKESLINSGFSNKPVVQLSKEKVQ-KKSYRKLKTTFVNVTSECPVNDVYNFNLNG--AD 879
L+ + K ++ L V+ KK +LK + N NL ++
Sbjct: 786 -LETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSN 844
Query: 880 DPIIKLGIQEFQATAKEACA--DRSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSD 937
+ +E + T + A +R + V + D + VK KDK I +N +
Sbjct: 845 QYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQ 904
Query: 938 TETEY-RCDDSKTDISWLREPKSKPQLIDYSRNKNVKNHKSGKSR----SSLEKGQPSSK 992
+ EY + + +S L + K Q S + + N++ G+ + K Q
Sbjct: 905 IKAEYISLAEHEAKMSSLSQSMRKVQ---DSNAEILANYRKGQEEIVTLHAEIKAQKKEL 961
Query: 993 MTPSKNITKKMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEE 1052
T + I K + KAT+ K+L + SE Q++S S +E K+E
Sbjct: 962 DTIQECIKVKYAPIVSFEECERKFKATE-----KELKDQLSEQTQKYSVSEEEVKKNKQE 1016
Query: 1053 NIHSRMKTVKLPKK-QQKVFCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSS 1111
N + + L K + K E E+ + + D + DLS +
Sbjct: 1017 NDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKT---DELNKQLKDLSQK-------Y 1066
Query: 1112 IEVTRCIEKITEKDFTQDYDCITKSISPYPKTSSLESLNS-NSGVGGTIKSPKNNEKNFL 1170
EV EK+ E++ Q + + + LE + + + GTI++ K K+
Sbjct: 1067 TEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQ 1126
Query: 1171 CASESCSPIPRPLFLPRHTPTKSNTIVNRKKISSLVLTQETQNSNSY-SDVSSYSSEERF 1229
E + T TK + ++ +K SS+ L + Q ++ +V + R
Sbjct: 1127 RCYEK----------EQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLRE 1176
Query: 1230 MEIESPHINENYIQSKREESHLASSLSKSSEGRE--------KTWFDMPCDATHVSGPTQ 1281
E ES + E + + E + +L K E RE T D+ + ++
Sbjct: 1177 KEEESQNKMEEVSKLQSEVQNTKQAL-KKLETREVVDLSKYKATKSDLETQISSLNEKLA 1235
Query: 1282 HLSRKRIYIEDNLSNSNEVEMEEKGER 1308
+L+RK + + + ++ + E+ K E+
Sbjct: 1236 NLNRKYEEVCEEVLHAKKKEISAKDEK 1262
Score = 31.6 bits (70), Expect = 6.2
Identities = 21/94 (22%), Positives = 47/94 (50%), Gaps = 12/94 (12%)
Query: 763 NVQSHRKAEKELTS-ELNSWDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKST 821
NV+SH++ + + E+ + D K++ + + + + + L Q+N+ DD++S
Sbjct: 272 NVKSHQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESE 331
Query: 822 RKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLK 855
R+ +SL+ +KEK ++S R ++
Sbjct: 332 REKLKSLL-----------AAKEKQHEESLRTIE 354
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 48.5 bits (114), Expect = 5e-05
Identities = 137/687 (19%), Positives = 266/687 (38%), Gaps = 77/687 (11%)
Query: 647 NKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQK 706
N+ K K + + + +++ K + +++K A+ ++H Q ++ + QK
Sbjct: 641 NEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLE---QK 697
Query: 707 NTENAKQSDWPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCD-KNPSASKNV- 764
+ E K+ +E T K+ L K IE+ +Y +L + + T + KN V
Sbjct: 698 SGELGKKI-----TELTLKNQTLQKEIEK--VYLDNKLLKEQAHNLTIEMKNHYVPLKVS 750
Query: 765 QSHRKAEKELTSELNS--WDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTR 822
+ +K+ + +LN D QK +K + ++ +SL +++
Sbjct: 751 EDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSR------------ 798
Query: 823 KLKESLINSGFSNKPVVQLSKEKVQ-KKSYRKLKTTFVNVTSECPVNDVYNFNLNG--AD 879
L+ + K ++ L V+ KK +LK + N NL ++
Sbjct: 799 -LETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSN 857
Query: 880 DPIIKLGIQEFQATAKEACA--DRSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSD 937
+ +E + T + A +R + V + D + VK KDK I +N +
Sbjct: 858 QYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQ 917
Query: 938 TETEY-RCDDSKTDISWLREPKSKPQLIDYSRNKNVKNHKSGKSR----SSLEKGQPSSK 992
+ EY + + +S L + K Q S + + N++ G+ + K Q
Sbjct: 918 IKAEYISLAEHEAKMSSLSQSMRKVQ---DSNAEILANYRKGQEEIVTLHAEIKAQKKEL 974
Query: 993 MTPSKNITKKMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEE 1052
T + I K + KAT+ K+L + SE Q++S S +E K+E
Sbjct: 975 DTIQECIKVKYAPIVSFEECERKFKATE-----KELKDQLSEQTQKYSVSEEEVKKNKQE 1029
Query: 1053 NIHSRMKTVKLPKK-QQKVFCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSS 1111
N + + L K + K E E+ + + D + DLS +
Sbjct: 1030 NDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKT---DELNKQLKDLSQK-------Y 1079
Query: 1112 IEVTRCIEKITEKDFTQDYDCITKSISPYPKTSSLESLNS-NSGVGGTIKSPKNNEKNFL 1170
EV EK+ E++ Q + + + LE + + + GTI++ K K+
Sbjct: 1080 TEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQ 1139
Query: 1171 CASESCSPIPRPLFLPRHTPTKSNTIVNRKKISSLVLTQETQNSNSY-SDVSSYSSEERF 1229
E + T TK + ++ +K SS+ L + Q ++ +V + R
Sbjct: 1140 RCYEK----------EQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLRE 1189
Query: 1230 MEIESPHINENYIQSKREESHLASSLSKSSEGRE--------KTWFDMPCDATHVSGPTQ 1281
E ES + E + + E + +L K E RE T D+ + ++
Sbjct: 1190 KEEESQNKMEEVSKLQSEVQNTKQAL-KKLETREVVDLSKYKATKSDLETQISSLNEKLA 1248
Query: 1282 HLSRKRIYIEDNLSNSNEVEMEEKGER 1308
+L+RK + + + ++ + E+ K E+
Sbjct: 1249 NLNRKYEEVCEEVLHAKKKEISAKDEK 1275
Score = 31.6 bits (70), Expect = 6.2
Identities = 21/94 (22%), Positives = 47/94 (50%), Gaps = 12/94 (12%)
Query: 763 NVQSHRKAEKELTS-ELNSWDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKST 821
NV+SH++ + + E+ + D K++ + + + + + L Q+N+ DD++S
Sbjct: 285 NVKSHQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESE 344
Query: 822 RKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLK 855
R+ +SL+ +KEK ++S R ++
Sbjct: 345 REKLKSLL-----------AAKEKQHEESLRTIE 367
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 47.0 bits (110), Expect = 1e-04
Identities = 81/408 (19%), Positives = 167/408 (40%), Gaps = 44/408 (10%)
Query: 628 NNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKE-QTDHIKIDKAE 686
++++ S+SS TL+ K K + SS SE + Y + + ++ ++
Sbjct: 769 SHKKHSSSSEKTLHS------KYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSA 822
Query: 687 VEVCKKHNQQQNHPKYSGQKNTENAK-QSDWPVESETTFKSVLLNKTIEESLIYRKKYIL 745
E K+ ++ H K + E +K + + P + T K L + S RK Y
Sbjct: 823 QEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAG 882
Query: 746 SKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGKEFTNVAESLI 805
SK + + +++ + + SH ++KE + +S+ ++ K K ++ SL
Sbjct: 883 SKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLP 942
Query: 806 SQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQL----SKEKVQKKSYRKLKTTF--- 858
N +K+ ST + S NS +N+ Q SKE ++++ +K+K
Sbjct: 943 DD-NGAWKSSKQRTSTSDSEGSCSNSE-NNRGKPQKHKHGSKENLKREHTKKVKEKLKGK 1000
Query: 859 VNVTSECPV-NDVYNFNLNGADDPIIKLGIQEFQATAKEACADRSIRLVGPRNHDELKSS 917
+ + P +++ P ++ G +E + + S N++ +K +
Sbjct: 1001 KDKKHKAPKRKQAFHW------QPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDN 1054
Query: 918 V----KTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSKPQLIDYSRN---- 969
+ K+ ++ + H + SD + ++ DDSK IS P ++ N
Sbjct: 1055 ILKTEKSSEEDLSGKHDTVTVSSDLD-QFTKDDSKLSIS--------PTALNTEENVACL 1105
Query: 970 KNVKNHKSGKSRSSLEKGQPSSKM---TPSKNITKKMDKTIPEGRIRL 1014
+N+++ + + Q M TP ++ K+++T P G RL
Sbjct: 1106 QNIQHVEESVPNGVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNARL 1153
Score = 35.0 bits (79), Expect = 0.56
Identities = 80/390 (20%), Positives = 140/390 (35%), Gaps = 66/390 (16%)
Query: 440 KSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFS 499
+S S ++ K SK N + + + E T+ S+ ++SE + V + + +
Sbjct: 888 ESNSERDVTKNSK---NDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSS-------T 937
Query: 500 NTSIPPRRRRIKPPLQMTSSAEKPSVSQTSENRVDNAASLKSRSSEG--RHRRDNIDKHI 557
NTS+P K Q TS+++ SEN K S E R + + +
Sbjct: 938 NTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKL 997
Query: 558 KTAKCVENTENKN---------VEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDNICG 608
K K ++ K +EF + E+ D ++ EK+ + DNI
Sbjct: 998 KGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILK 1057
Query: 609 NKIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTG 668
+ S+ +L T S D + TK S SIS
Sbjct: 1058 TEKSSE---------EDLSGKHDTVTVSSDL--------DQFTKDDSKLSISP------- 1093
Query: 669 KVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVL 728
++ E C ++ Q H + S E+ Q+D +E T +S
Sbjct: 1094 -----------TALNTEENVACLQNIQ---HVEESVPNGVEDVLQTDDNMEICTPDRS-- 1137
Query: 729 LNKTIEESLIYRKKYILSKDVNTA----TCDKNPSASKNVQSHRKAEKELTSELNSWDSK 784
+EE+ + + D+N ++P A Q +E ++ E+ DS
Sbjct: 1138 SPAKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSS 1197
Query: 785 QKKMREKSKGKEFTNVAE-SLISQINKRYK 813
+ + VAE S I+ I+K++K
Sbjct: 1198 SASLASAGESTGKKEVAEKSQINLIDKKWK 1227
Score = 32.0 bits (71), Expect = 4.7
Identities = 85/450 (18%), Positives = 171/450 (38%), Gaps = 56/450 (12%)
Query: 627 CNNQRASTSSG---------DTLNQDIVINKKLTKQKSSS----SISDHNSEGTGKVKYK 673
C+ +R+S SS D D + LT S S S S G+ + +
Sbjct: 479 CDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTA 538
Query: 674 KEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQ--SDWPVESETTFKSVLLNK 731
+ + H + + + + H K + + + A Q + PV++E ++ N+
Sbjct: 539 SKSSSHSRSRSKS-----RSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNE 593
Query: 732 TIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREK 791
+ + ++++++ +P S+ + +K K + +K +
Sbjct: 594 NVVV------QPVVAENIPVIPLSDSPPPSR-WKPGQKPWKPSYERIQEMKAKTTHLLPI 646
Query: 792 SKGKEFTNVAES-LISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKS 850
N+ E+ S +KR K + +ST K S +S S + + S+ + +S
Sbjct: 647 QSTYSLANIKETGSSSSYHKREKNSESDQSTYS-KYSDRSSESSPRSRSRSSRSRSYSRS 705
Query: 851 YRKLKTTFVNVT-SECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRSIRLVGPR 909
Y + ++ + + S P + ++ N + ++ A R +R G +
Sbjct: 706 YTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKK 765
Query: 910 NHDELK----SSVKTKDKKIITNHQKKNLF-----SDTETEYRCDDSKTDISWLR--EPK 958
N K SS KT K + + + S + +Y D ++ + + + K
Sbjct: 766 NSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEK 825
Query: 959 SKPQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKA 1018
K ++ + NK KN KS+S E S K T +N++ + R
Sbjct: 826 EKQGQMERTHNKQEKNRGEEKSKSERECPH-SKKRTLKENLSDHL------------RNG 872
Query: 1019 TKTK-KNYKDLS-NSESECEQEFSHSFKEN 1046
+K K KNY +SES E++ + + K +
Sbjct: 873 SKPKRKNYAGSKWDSESNSERDVTKNSKND 902
>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
Length = 1884
Score = 46.2 bits (108), Expect = 2e-04
Identities = 112/567 (19%), Positives = 223/567 (39%), Gaps = 95/567 (16%)
Query: 377 SLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQILVPES----------- 425
SL+ T+++ ++ R KQ I KTS++I + S+ V ++
Sbjct: 146 SLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELL 205
Query: 426 QISPVG-EELVSLKEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTT-------PSKRKM 477
QI+P G + +SL K+ EF++ + N++ +N+ L T P K +
Sbjct: 206 QITPQGTRDEISLDSAKKAACEFSETD--VTNTEHHQPSNNDLNTTEKRAAERHPEKYQG 263
Query: 478 SEASMI-VSGADRYTMRSPVLFSNTSIPPRRRRIK-PPLQMTSSAEKPSVSQTSENR-VD 534
S S + V T S + N+S+ + R+ + + +++P ++++ NR
Sbjct: 264 SSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQHNRWAG 323
Query: 535 NAASLKSRSSEGRHRRDNIDK---------HIKTAKCVEN----------TENKNVEFPN 575
+ + R + ++ +++ + + C EN T N +++ N
Sbjct: 324 SKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNSSIQKVN 383
Query: 576 QNFSELQDVI--PDSQAAEKRDHTILPGVLDNICGNKIHSKWACWTPVTNIE-------L 626
+ FS +++ DS E + + VLD + N++ + + +
Sbjct: 384 EWFSRSDELLGSDDSHDGESESNAKVADVLDVL--NEVDEYSGSSEKIDLLASDPHEALI 441
Query: 627 CNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEG------------------TG 668
C ++R + S ++ +D + K K+ S ++S H +E T
Sbjct: 442 CKSERVHSKSVESNIEDKIFGKTYRKKASLPNLS-HVTENLIIGAFVTEPQIIQERPLTN 500
Query: 669 KVKYKKEQTDHIK----IDKAEVEVCKKH---NQQQNHPKYSGQ------KNTENAKQSD 715
K+K K+ T + I KA++ V K NQ N + +GQ EN + D
Sbjct: 501 KLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKTKGD 560
Query: 716 WPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELT 775
+++E + +ES K +S ++ + N SK + +R K T
Sbjct: 561 -SIQNEKNPNPI--ESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSST 617
Query: 776 SELNSWDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKL-----KESLIN 830
+++ + + E + S +I K+ + ++ +R L KE
Sbjct: 618 RHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATG 677
Query: 831 SGFSNKPVVQLSKEKVQKKSYRKLKTT 857
+ SNKP Q SK + ++ +LK T
Sbjct: 678 AKKSNKPNEQTSK-RHDSDTFPELKLT 703
>gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]
Length = 1816
Score = 46.2 bits (108), Expect = 2e-04
Identities = 112/567 (19%), Positives = 223/567 (39%), Gaps = 95/567 (16%)
Query: 377 SLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQILVPES----------- 425
SL+ T+++ ++ R KQ I KTS++I + S+ V ++
Sbjct: 99 SLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELL 158
Query: 426 QISPVG-EELVSLKEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTT-------PSKRKM 477
QI+P G + +SL K+ EF++ + N++ +N+ L T P K +
Sbjct: 159 QITPQGTRDEISLDSAKKAACEFSETD--VTNTEHHQPSNNDLNTTEKRAAERHPEKYQG 216
Query: 478 SEASMI-VSGADRYTMRSPVLFSNTSIPPRRRRIK-PPLQMTSSAEKPSVSQTSENR-VD 534
S S + V T S + N+S+ + R+ + + +++P ++++ NR
Sbjct: 217 SSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQHNRWAG 276
Query: 535 NAASLKSRSSEGRHRRDNIDK---------HIKTAKCVEN----------TENKNVEFPN 575
+ + R + ++ +++ + + C EN T N +++ N
Sbjct: 277 SKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNSSIQKVN 336
Query: 576 QNFSELQDVI--PDSQAAEKRDHTILPGVLDNICGNKIHSKWACWTPVTNIE-------L 626
+ FS +++ DS E + + VLD + N++ + + +
Sbjct: 337 EWFSRSDELLGSDDSHDGESESNAKVADVLDVL--NEVDEYSGSSEKIDLLASDPHEALI 394
Query: 627 CNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEG------------------TG 668
C ++R + S ++ +D + K K+ S ++S H +E T
Sbjct: 395 CKSERVHSKSVESNIEDKIFGKTYRKKASLPNLS-HVTENLIIGAFVTEPQIIQERPLTN 453
Query: 669 KVKYKKEQTDHIK----IDKAEVEVCKKH---NQQQNHPKYSGQ------KNTENAKQSD 715
K+K K+ T + I KA++ V K NQ N + +GQ EN + D
Sbjct: 454 KLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKTKGD 513
Query: 716 WPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELT 775
+++E + +ES K +S ++ + N SK + +R K T
Sbjct: 514 -SIQNEKNPNPI--ESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSST 570
Query: 776 SELNSWDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKL-----KESLIN 830
+++ + + E + S +I K+ + ++ +R L KE
Sbjct: 571 RHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATG 630
Query: 831 SGFSNKPVVQLSKEKVQKKSYRKLKTT 857
+ SNKP Q SK + ++ +LK T
Sbjct: 631 AKKSNKPNEQTSK-RHDSDTFPELKLT 656
>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
Length = 1863
Score = 46.2 bits (108), Expect = 2e-04
Identities = 112/567 (19%), Positives = 223/567 (39%), Gaps = 95/567 (16%)
Query: 377 SLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQILVPES----------- 425
SL+ T+++ ++ R KQ I KTS++I + S+ V ++
Sbjct: 146 SLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELL 205
Query: 426 QISPVG-EELVSLKEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTT-------PSKRKM 477
QI+P G + +SL K+ EF++ + N++ +N+ L T P K +
Sbjct: 206 QITPQGTRDEISLDSAKKAACEFSETD--VTNTEHHQPSNNDLNTTEKRAAERHPEKYQG 263
Query: 478 SEASMI-VSGADRYTMRSPVLFSNTSIPPRRRRIK-PPLQMTSSAEKPSVSQTSENR-VD 534
S S + V T S + N+S+ + R+ + + +++P ++++ NR
Sbjct: 264 SSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQHNRWAG 323
Query: 535 NAASLKSRSSEGRHRRDNIDK---------HIKTAKCVEN----------TENKNVEFPN 575
+ + R + ++ +++ + + C EN T N +++ N
Sbjct: 324 SKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNSSIQKVN 383
Query: 576 QNFSELQDVI--PDSQAAEKRDHTILPGVLDNICGNKIHSKWACWTPVTNIE-------L 626
+ FS +++ DS E + + VLD + N++ + + +
Sbjct: 384 EWFSRSDELLGSDDSHDGESESNAKVADVLDVL--NEVDEYSGSSEKIDLLASDPHEALI 441
Query: 627 CNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEG------------------TG 668
C ++R + S ++ +D + K K+ S ++S H +E T
Sbjct: 442 CKSERVHSKSVESNIEDKIFGKTYRKKASLPNLS-HVTENLIIGAFVTEPQIIQERPLTN 500
Query: 669 KVKYKKEQTDHIK----IDKAEVEVCKKH---NQQQNHPKYSGQ------KNTENAKQSD 715
K+K K+ T + I KA++ V K NQ N + +GQ EN + D
Sbjct: 501 KLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKTKGD 560
Query: 716 WPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELT 775
+++E + +ES K +S ++ + N SK + +R K T
Sbjct: 561 -SIQNEKNPNPI--ESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSST 617
Query: 776 SELNSWDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKL-----KESLIN 830
+++ + + E + S +I K+ + ++ +R L KE
Sbjct: 618 RHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATG 677
Query: 831 SGFSNKPVVQLSKEKVQKKSYRKLKTT 857
+ SNKP Q SK + ++ +LK T
Sbjct: 678 AKKSNKPNEQTSK-RHDSDTFPELKLT 703
>gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]
Length = 1260
Score = 45.8 bits (107), Expect = 3e-04
Identities = 84/399 (21%), Positives = 149/399 (37%), Gaps = 64/399 (16%)
Query: 442 KSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNT 501
+ P EF P+ + D GN +S+++ K G D P +++
Sbjct: 759 EDPSEFETPA--LSTKDSGNLYDSEIQNVLGVKH----------GHDM----QPACQNDS 802
Query: 502 SIPPRRRRIKPPLQMTSSAEK-PSVSQTSEN--------RVDNAASLKSRSSEGRHRRDN 552
I KP L + +E P +Q EN DN SL + E
Sbjct: 803 KIGK-----KPRLNVCQKSEIIPETNQIYENDNKGVHDLEKDNFFSLTPKDKETISENLQ 857
Query: 553 IDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDNICGNKIH 612
+ +T + ++ QN EL+ + D ++AE+ + I N NK++
Sbjct: 858 VTNEFQTVDLLIKDNGNLCDYDTQNILELKKYVTDRKSAEQNESKI------NKLRNKVN 911
Query: 613 SKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKY 672
K + + I N++ A T + D +NK K + I+ H E
Sbjct: 912 WKTEIISEMNQIYEDNDKDAHVQESYTKDLDFKVNKSKQKLECQDIINKHYMEVNSN--- 968
Query: 673 KKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKT 732
+KE D I +D +V KK ++ + + +N S S+T+ +
Sbjct: 969 EKESCDQI-LD--SYKVVKKRKKESSCKAKNILTKAKNKLASQLTESSQTSI-------S 1018
Query: 733 IEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKS 792
+E L K+I T+ D +P N K +K+ T+ LN D + E
Sbjct: 1019 LESDL----KHI------TSEADSDPG---NPVELCKTQKQSTTTLNKKD--LPFVEEIK 1063
Query: 793 KGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINS 831
+G+ + S+ KR + D + ++ E +++S
Sbjct: 1064 EGECQVKKVNKMTSKSKKRKTSIDPSPESHEVMERILDS 1102
>gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]
Length = 1265
Score = 45.8 bits (107), Expect = 3e-04
Identities = 84/399 (21%), Positives = 149/399 (37%), Gaps = 64/399 (16%)
Query: 442 KSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNT 501
+ P EF P+ + D GN +S+++ K G D P +++
Sbjct: 759 EDPSEFETPA--LSTKDSGNLYDSEIQNVLGVKH----------GHDM----QPACQNDS 802
Query: 502 SIPPRRRRIKPPLQMTSSAEK-PSVSQTSEN--------RVDNAASLKSRSSEGRHRRDN 552
I KP L + +E P +Q EN DN SL + E
Sbjct: 803 KIGK-----KPRLNVCQKSEIIPETNQIYENDNKGVHDLEKDNFFSLTPKDKETISENLQ 857
Query: 553 IDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDNICGNKIH 612
+ +T + ++ QN EL+ + D ++AE+ + I N NK++
Sbjct: 858 VTNEFQTVDLLIKDNGNLCDYDTQNILELKKYVTDRKSAEQNESKI------NKLRNKVN 911
Query: 613 SKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKY 672
K + + I N++ A T + D +NK K + I+ H E
Sbjct: 912 WKTEIISEMNQIYEDNDKDAHVQESYTKDLDFKVNKSKQKLECQDIINKHYMEVNSN--- 968
Query: 673 KKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKT 732
+KE D I +D +V KK ++ + + +N S S+T+ +
Sbjct: 969 EKESCDQI-LD--SYKVVKKRKKESSCKAKNILTKAKNKLASQLTESSQTSI-------S 1018
Query: 733 IEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKS 792
+E L K+I T+ D +P N K +K+ T+ LN D + E
Sbjct: 1019 LESDL----KHI------TSEADSDPG---NPVELCKTQKQSTTTLNKKD--LPFVEEIK 1063
Query: 793 KGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINS 831
+G+ + S+ KR + D + ++ E +++S
Sbjct: 1064 EGECQVKKVNKMTSKSKKRKTSIDPSPESHEVMERILDS 1102
>gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]
Length = 1261
Score = 45.8 bits (107), Expect = 3e-04
Identities = 84/399 (21%), Positives = 149/399 (37%), Gaps = 64/399 (16%)
Query: 442 KSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNT 501
+ P EF P+ + D GN +S+++ K G D P +++
Sbjct: 759 EDPSEFETPA--LSTKDSGNLYDSEIQNVLGVKH----------GHDM----QPACQNDS 802
Query: 502 SIPPRRRRIKPPLQMTSSAEK-PSVSQTSEN--------RVDNAASLKSRSSEGRHRRDN 552
I KP L + +E P +Q EN DN SL + E
Sbjct: 803 KIGK-----KPRLNVCQKSEIIPETNQIYENDNKGVHDLEKDNFFSLTPKDKETISENLQ 857
Query: 553 IDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDNICGNKIH 612
+ +T + ++ QN EL+ + D ++AE+ + I N NK++
Sbjct: 858 VTNEFQTVDLLIKDNGNLCDYDTQNILELKKYVTDRKSAEQNESKI------NKLRNKVN 911
Query: 613 SKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKY 672
K + + I N++ A T + D +NK K + I+ H E
Sbjct: 912 WKTEIISEMNQIYEDNDKDAHVQESYTKDLDFKVNKSKQKLECQDIINKHYMEVNSN--- 968
Query: 673 KKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKT 732
+KE D I +D +V KK ++ + + +N S S+T+ +
Sbjct: 969 EKESCDQI-LD--SYKVVKKRKKESSCKAKNILTKAKNKLASQLTESSQTSI-------S 1018
Query: 733 IEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKS 792
+E L K+I T+ D +P N K +K+ T+ LN D + E
Sbjct: 1019 LESDL----KHI------TSEADSDPG---NPVELCKTQKQSTTTLNKKD--LPFVEEIK 1063
Query: 793 KGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINS 831
+G+ + S+ KR + D + ++ E +++S
Sbjct: 1064 EGECQVKKVNKMTSKSKKRKTSIDPSPESHEVMERILDS 1102
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 45.8 bits (107), Expect = 3e-04
Identities = 160/887 (18%), Positives = 338/887 (38%), Gaps = 103/887 (11%)
Query: 336 EKVQIYSIEVRESKKLLTIILKNTV-KISKREGKEL-LLYFDASLEITNVTQKIFGATKH 393
E+++ +++ +L + NT ++ ++ EL L D + + +T+K
Sbjct: 413 EQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKT--GKLQ 470
Query: 394 RESIRKQGISVAKTSLHILFDASGSQILVPESQISPVGEELVSLKEKSKSPKEFAKP--- 450
+E ++K+ A T L + + + EE+ S K + E A+
Sbjct: 471 QEEVQKKNAEQAATQLKVQLQEAERR-----------WEEVQSYIRKRTAEHEAAQQDLQ 519
Query: 451 SKYIKNSDKGNRNNSQLEKTTPSKRKMSEASM--IVSGADRYTMRSPVLFSNTSIPPRRR 508
SK++ ++ +S+L T SK+++ + M + S R + I +
Sbjct: 520 SKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNE 579
Query: 509 RIKPPLQMTSS--AEKPSVSQTSENR----VDNAASLKSRSSEGRHRRDNIDKHIKTAKC 562
+K +Q S A + S S +E + +K RD + + K
Sbjct: 580 ALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKD 639
Query: 563 VENTE-------NKNVEFPNQNFSELQDVIPDSQAAEKRDHTI--LPGVLDNICGNKIHS 613
++N K N+ + ++ Q+ +D I L L + NK+
Sbjct: 640 IQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKME- 698
Query: 614 KWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLT---KQKSSSSISDHNSEGTGKV 670
++ Q+ T + N+D+V + K + ++ + G +V
Sbjct: 699 EFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQV 758
Query: 671 KYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLN 730
K+E+ + I+ + + + + + + + + S E K+ + +
Sbjct: 759 ATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKI-------- 810
Query: 731 KTIEESLIYRKKYILSKDVNTATCDKNPSASK----NVQSHRKAEKELTSEL----NSWD 782
K++EE L + +K+ + A K NVQ + + +TS++ N
Sbjct: 811 KSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLK 870
Query: 783 SKQKKMRE-----KSKGKEFTNVAESL--ISQINKRYKTKDDIKSTRKLKESLINSGFSN 835
K+++M + K K+ N + L + + N+ K + LKE+ S F
Sbjct: 871 GKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEE 930
Query: 836 KPVVQLSKEKVQKKSYRKLKTTFVNVTSECPV-NDVYNFNLNGADDPIIKLGIQEFQATA 894
+V KE K+ LK +++S+ + DV + N I +L Q +Q +
Sbjct: 931 LEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDEN-KLFKSQIEQLKQQNYQQAS 989
Query: 895 KEACADRSIRLVGPRNH---------DELKSSVKTKDKKIITNHQKKNLFSDTETEYRCD 945
+ ++++ R D LK +V+ + KK N++++ E E +
Sbjct: 990 SFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKK---NNERQQQVEAVELEAKEV 1046
Query: 946 DSK--------TDIS---WLR--EPKSKPQLIDYSRNKNVK--NHKSGKSRS-----SLE 985
K +++S WL E K+K + S ++ VK HK ++ LE
Sbjct: 1047 LKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLE 1106
Query: 986 KGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKE 1045
+ S + ++ I +K+ +++ + + K ++ K K + +S + EQE E
Sbjct: 1107 CEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSE 1166
Query: 1046 NIPVKEENIHSRMKTVKLPKKQQKVFCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSL 1105
N ++ ++L K + + TE K N +L K N L
Sbjct: 1167 NKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDL 1226
Query: 1106 SGSPSSIEV--TRCIEKITEKDFTQDYDCITKSISPYPKTSSLESLN 1150
+ S+E+ ++ ++ + ++ D +SP ++S E+++
Sbjct: 1227 HKAQQSLELIQSKIVKAAGDTTVIENSD-----VSPETESSEKETMS 1268
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 45.8 bits (107), Expect = 3e-04
Identities = 228/1305 (17%), Positives = 487/1305 (37%), Gaps = 154/1305 (11%)
Query: 316 SFYIAGDNDDHQWEAVTVPEEKVQIYSIEVRESKKL----------------LTIILKNT 359
S Y+ + Q E++ + E ++Q +I KL L L+ +
Sbjct: 520 SEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 579
Query: 360 VKISKREGKELLLYFDASLEITNVTQKIFGATKHR---ESIRKQGISVAKTSLHILFDAS 416
++ +K + K+L ++ +A N + KH+ ES++ Q ++ L
Sbjct: 580 LQENKNQSKDLAVHLEAEKNKHNKEITVM-VEKHKTELESLKHQQDALWTEKL------- 631
Query: 417 GSQILVPESQISPVGEELVSLKEKSKSPKE-FAKPSKYIKNSDKGNRNNSQLEKTTPSKR 475
Q+L + Q E+ L+EK + KE K + I + N LEK +
Sbjct: 632 --QVLKQQYQT-----EMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQT 684
Query: 476 KM----SEASMIVSGADRYTMRSPVLFSNTSIPPRRRRIKPPLQMTSSAEK-PSVSQTSE 530
++ SE S ++ + VL T + K Q ++ S+ + E
Sbjct: 685 ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHE 744
Query: 531 NRVDNAA-SLKSRSSEGRHRRDNIDKHIKTAKC-VENTEN--KNVEFPNQNFSELQDVIP 586
+ +LK + ++ DKH+K + VEN E K E Q S DV
Sbjct: 745 VSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQ 804
Query: 587 DSQAA--------EKRDHTILPGVLDNICGNKIHSKWACWTPVTNIELCNNQRASTSSGD 638
Q+A E++ + +LD + +K ++C A
Sbjct: 805 SYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQ 864
Query: 639 TLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQN 698
L Q + +QK S + S+ K ++EQT I ++K + + + Q++
Sbjct: 865 DLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNK-EQEQTKQILVEKENMILQMREGQKKE 923
Query: 699 HPKYSGQKNTENAKQSDWPVESETTFKSVL------------LNKTIEESLIYRKKYILS 746
+ + + + E ET FK+ + +T+++ L+ ++ +
Sbjct: 924 IEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKK 983
Query: 747 KDVNTAT------CDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGKEFTNV 800
+ NTA N + Q++ + S L + +Q + + +E +V
Sbjct: 984 ELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDV 1043
Query: 801 AESLISQINKRYKTKDDI---------KSTRKLKESLINSGFSNKPVVQLSKEKVQKKSY 851
++N++ + +I + +LK+ ++ G + +++KE K
Sbjct: 1044 ISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKE---EMNKEITWLKEE 1100
Query: 852 RKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRSI---RLV-- 906
+ T +N E + N D+ +K +++ + ++ + + +LV
Sbjct: 1101 GVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVEL 1160
Query: 907 ------GPRNHDELKSSVKTKDKK---IITNHQKKNL-FSDTETEYRCDDSKTDISWLRE 956
R EL S +KT D++ + ++H+K N D E++ + I
Sbjct: 1161 KMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDIC 1220
Query: 957 PKSKPQLIDYSRNK--NVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIR- 1013
K L++ N+ N+ + K+ S + Q + + K + E ++R
Sbjct: 1221 CKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQ 1280
Query: 1014 LPRKATKTKKNYKDLSNSESECEQEFSHSFK---ENIPVKEENIHSRMKTVKLPKKQQKV 1070
L + +++ ++ E E + S K E++ ++E + + +++
Sbjct: 1281 LTEEQNTLNISFQQATHQLEEKENQIK-SMKADIESLVTEKEALQKEGGNQQQAASEKES 1339
Query: 1071 FCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDY 1130
+ +KELS+ +L+K+ +++ +++S S + ++++ I ++EK+
Sbjct: 1340 CITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSI-SLSEKE----- 1393
Query: 1131 DCITKSISPYPKTSSLESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTP 1190
+IS K E V K + A E F
Sbjct: 1394 ----AAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNK-FSEWKKK 1448
Query: 1191 TKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQSKREESH 1250
+S ++ + L + E ++ +Y + ++ E N+ + K E
Sbjct: 1449 AQSRFTQHQNTVKELQIQLELKSKEAYEK----DEQINLLKEELDQQNKRFDCLKGEMED 1504
Query: 1251 LASSLSKSSEGREKTWFDMPCDATHVSGPTQHLSRKRIYIED------NLSNSNEVEMEE 1304
S + K E ++ + H+++K I IE N + ++E +E
Sbjct: 1505 DKSKMEKKESNLET---ELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKE 1561
Query: 1305 KGERRANLLPKKLCKIEDADHHIHKMSESVSSLSTNDFSI--PWETWQNEFAGIEMTYET 1362
++ + E+ D+ + + E + +L +S+ ET + E + ++ ++
Sbjct: 1562 LVQKLQHFQELG----EEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKS 1617
Query: 1363 YERLNSEFKRRNNIRHKMLSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIIIEEL 1422
E E K + + + + A+Q + + Q +K ++++ L
Sbjct: 1618 KE---EELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHL 1674
Query: 1423 ENFEKDSQSLKDLEKEFVDFWEKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCNTDSEETV 1482
+ L++ E+E + +K + + S+ + L + ++ AK+V T+ EE
Sbjct: 1675 SEL---NTKLQEREREV----HILEEKLKSVESSQSETLIVPRS--AKNVAAYTEQEEA- 1724
Query: 1483 FTSEMCLMK---EDMKVLQDRLLKDMLEEELLNVRRELMSVFMSH 1524
S+ C+ K E + VLQ L + E+ L V +E SH
Sbjct: 1725 -DSQGCVQKTYEEKISVLQRNLTEK--EKLLQRVGQEKEETVSSH 1766
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 44.7 bits (104), Expect = 7e-04
Identities = 176/1067 (16%), Positives = 368/1067 (34%), Gaps = 151/1067 (14%)
Query: 455 KNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNTSIPPRRRRIKPPL 514
++ +K +R + E+ S R + G DR R RR ++
Sbjct: 424 RDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDT---------RDRRELRDSR 474
Query: 515 QMTSSAEKPSVSQTSENRVDNAASLKSRSSEGRHRRDNIDKHIKTAKCVENT-------- 566
M S E S+ ++ D S +R + R+ D H K E +
Sbjct: 475 DMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHL 534
Query: 567 --ENKNVEFPNQNFSELQDVIPDSQAAEKRDHTI-LP---------GVLDNICGNK-IHS 613
E+ E N++ +E + I + + R LP +D+ N H
Sbjct: 535 REESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHD 594
Query: 614 KWACWTPVTNI----ELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGK 669
W + E N +A SS + + + +++ +++ S +G
Sbjct: 595 SWETRSSYPERDRYPERDNRDQARDSSFERRHGER--DRRDNRERDQRPSSPIRHQGRND 652
Query: 670 VKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLL 729
+ E+ + ++D+ + ++ ++ + ++ E ++ D E E +
Sbjct: 653 ELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER--- 709
Query: 730 NKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMR 789
+ E K+ +D D++ + + R EKE E + ++++ R
Sbjct: 710 ERAREREREREKERDRERDR-----DRDHDRERERERERDREKEREREREERERERERER 764
Query: 790 EKSKGKEFTNVAESLISQINKR---YKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKV 846
E+ + +E + +R ++ KD + R+ K I + + E+
Sbjct: 765 ERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPR---DGHDERK 821
Query: 847 QKKSYRKLKTTFVNVT-----SECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADR 901
KK YR + + P +D Y N DD K +
Sbjct: 822 SKKRYRNEGSPSPRQSPKRRREHSPDSDAY----NSGDDKNEKHRLLS------------ 865
Query: 902 SIRLVGPRNHDELKSSVKTKDKK-IITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSK 960
++V P+ L S T+D++ +K ++ Y + K +S + + + +
Sbjct: 866 --QVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQ 923
Query: 961 PQLIDYSRNK--NVKNHKSGKSRSSLEKGQPSSK---MTPSKNITKK-----------MD 1004
++++ SR + ++ H + R + ++ +K K I KK ++
Sbjct: 924 TEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIE 983
Query: 1005 KTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTVKLP 1064
T +G++ P+K K K K S+ + + + +E + K + P
Sbjct: 984 TTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSD------------ISDEEAAQQSKKKRGP 1031
Query: 1065 KKQQKVFCAETEKELSKQWK-NSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITE 1123
+ T++EL + + +L+D+ + S S P EVT T
Sbjct: 1032 RTPP----ITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATA 1087
Query: 1124 KDFTQDYDCITKSISPYPKTSSLESLNSNSGVGGTIKSPKNN-EKNFLCASESCSPIPRP 1182
++ + P P ++ + + + T + + + + S S +P
Sbjct: 1088 TTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATP---- 1143
Query: 1183 LFLPRHTPTKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHIN-ENY 1241
T T +NT N D R ++E+PH+ E+
Sbjct: 1144 ------TNTTNNTFAN-------------------EDSHRKCHRTRVEKVETPHVTIEDA 1178
Query: 1242 IQSKREESHLASSLSKSSEGREKTWFDMPC---DATHVSGPTQHLSRKRIYIEDNLSNSN 1298
K + +SSL + R T + D+ H SG Q RKR+ +
Sbjct: 1179 QHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQS-GRKRVLHSGSRDREK 1237
Query: 1299 EVEMEEKGERRANLLPKKL---CKIEDADHHIHKMSESVSSLSTNDFSIPWETWQNEFAG 1355
+E GER++ + K + +D + S S +D + + +
Sbjct: 1238 TKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRD 1297
Query: 1356 IEMTYETYERLNSEFKRRNNIRHKMLSYFTTQSW--KTAQQHLRTMNHQSQDSRIKKLDK 1413
+ YE + R + R + + W + LR + + + + LD+
Sbjct: 1298 RLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDR 1357
Query: 1414 FQFIIIEELENFEKDSQSLKDLEKEFVDFWEKIFQKFSAYQKSEQQR 1460
+ +I + ++D +D ++ F + ++ A + E +R
Sbjct: 1358 ERERLISDSVERDRD----RDRDRTFESSQIESVKRCEAKLEGEHER 1400
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 43.9 bits (102), Expect = 0.001
Identities = 182/1009 (18%), Positives = 400/1009 (39%), Gaps = 198/1009 (19%)
Query: 651 TKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTEN 710
T K S+ + +V+ K Q + +A +E +KH+ Q N TE
Sbjct: 1737 TLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNV--------TEE 1788
Query: 711 AKQSDWPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKA 770
QS P E+E ++SL + S+ V +A NP+ SK+ SH
Sbjct: 1789 GTQSI-PGETEE-----------QDSLSMSTRPTCSESVPSAK-SANPAVSKDFSSH--- 1832
Query: 771 EKELTSELNSWDSKQKKM----REKSKGKEFTNVAESLISQINKRYKTKD-DIKSTRK-- 823
E+ + L D ++++ EK K KEF+ E+ + + + TKD ++K ++
Sbjct: 1833 -DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEV 1891
Query: 824 LKESLINSGFSN--------KPVVQLSKEKVQKKSYRKLKTTFVNVTSECP-------VN 868
K +L+N K + K+ ++++ +L ++ + C N
Sbjct: 1892 TKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKN 1951
Query: 869 DVYNFNLNGADDPIIKLGIQEFQATAKEACADRSIRL------------VGPRNH-DELK 915
++ + + +L ++ Q ++ + IR G ++H EL+
Sbjct: 1952 ELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQ 2011
Query: 916 SSVKTKDKKI----------------ITNHQKKNLFSDTETEYRCDDSKTDISWLREPKS 959
+K K +++ + K F TE++ + +K +++ E +
Sbjct: 2012 ELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRK 2071
Query: 960 KPQ--------LIDYSRNK-------NVKNHKSGKSRSSLEKGQPSSK------------ 992
K Q L+D ++++ N+K K +S K Q K
Sbjct: 2072 KAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAE 2131
Query: 993 ---MTPSKNITKKMD----------KTIPEGRIRLPRKATKTKKNYKDLSNSESEC---- 1035
+ KN+ +K+D +TI E ++ L +K + ++ ++L ++ ++
Sbjct: 2132 EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFT 2191
Query: 1036 --------------------EQEFS---HSFKENIPVKEEN---IHSRMKTVKLPKKQQK 1069
E++FS S +E I +KE+N + +++ + + ++ K
Sbjct: 2192 KSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELK 2251
Query: 1070 VFCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQD 1129
+ + E + + W++ + + ++ D S +E TR + ++ + +
Sbjct: 2252 INISRLEHD-KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAK- 2309
Query: 1130 YDCITKSISPY--PKTSSLESLNSNSG-VGGTIKSPKNNEKNFLCASESCSPIPRPLFLP 1186
+ KS+ ++SLE G + G I+ + + +N + S + L
Sbjct: 2310 LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQN---SKFSYEQLETDLQAS 2366
Query: 1187 RHTPTKSNTIVNRK--KISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQS 1244
R ++ + +N K KI SL+ +E + +++ +E E+ EN +
Sbjct: 2367 RELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKE-IKEL------ENLLSQ 2419
Query: 1245 KREESHLASSLSKSSEGREKTWFDMPCDATHVSGPTQHLSRKRIYIEDNLSNSNE----- 1299
+ EE+ + +K + +KT M T Q ++ +++ S N+
Sbjct: 2420 EEEENIVLEEENKKAV--DKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIV 2477
Query: 1300 VEMEEKGERRANLLPKKLCKIEDADHHIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMT 1359
+ ++ ER +++ +K I++A +K+ E + L ++ + +E A ++
Sbjct: 2478 GDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSH-----MDDLNSENAKLDAE 2532
Query: 1360 YETY-ERLNSEFKRRNNIRHKMLSYFTTQS------WKTAQQHLRTMNHQSQDSRIKKLD 1412
Y E LN +++ + ++L Q+ + ++ L+ ++D R + +
Sbjct: 2533 LIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLR-RSFN 2591
Query: 1413 KFQFIIIEELENFEKDSQSLK----DLEKEFVDFWEK-IFQKFSAYQKSEQQRLHLLKTS 1467
Q EE ++ K+ +SLK L ++ E+ + A K +++ +H L
Sbjct: 2592 ALQ----EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSAL 2647
Query: 1468 LAKSVFCNTDSEETVFTSEMCLMKEDMKVLQDRLLKDMLEEELLNVRRE 1516
+ S + EE + +C+ KE K + + ++D L++EL ++ +
Sbjct: 2648 FSSSQKRIAELEEEL----VCVQKEAAKKVGE--IEDKLKKELKHLHHD 2690
Score = 32.3 bits (72), Expect = 3.6
Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 19/152 (12%)
Query: 720 SETTFKSVLLNKTIEESLIYRKKY---ILSKDVNTATCDKNPSASKN-VQSHRKAEKELT 775
SET F +N T E SL + +K +LSKD S N VQS KA L
Sbjct: 2786 SETAFS---MNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQ 2842
Query: 776 SELNSWDSKQKKMREKSKGKE------FTNVAE--SLISQINKRYKTKDD-IKSTRKLKE 826
+E + ++ +K R+ +GK+ T+ AE SL ++ +D +K + L++
Sbjct: 2843 NERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQ 2902
Query: 827 SLINSGFSNKPVVQLSKEKVQKKSYRKLKTTF 858
+ N+ + +L K Q + Y+ F
Sbjct: 2903 QYLQ---INQEITELHPLKAQLQEYQDKTKAF 2931
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform 1
[Homo sapiens]
Length = 1722
Score = 43.9 bits (102), Expect = 0.001
Identities = 86/473 (18%), Positives = 185/473 (39%), Gaps = 65/473 (13%)
Query: 617 CWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKEQ 676
CW +E + D +N ++ +K+ K+ K K +E
Sbjct: 209 CWMKQFKVEKKKLENIQKQEQDKMNDELYKEEKIWKE---------------KFKQHEEY 253
Query: 677 TDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKTIEES 736
++ + E K Q++ +KN+ +Q++ V+ + +K+ + +
Sbjct: 254 IRNLHLQMEEERTRFKDQQEK-------EKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPI 306
Query: 737 LIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGKE 796
+ K+ I SK + + + + + E + KQK+ K + KE
Sbjct: 307 I---KEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKE 363
Query: 797 F---TNVAESLISQINKRYK--TKDDIKSTRKLKESLINSGFSNKPVV---------QLS 842
+ N+ + Q+ + K ++D + +L SG++NK + ++
Sbjct: 364 YEEKKNIVKQEREQLISKEKIILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIA 423
Query: 843 KEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRS 902
K V + S +K + + + E N N I+K + Q KE+ + ++
Sbjct: 424 KNLVDENS-KKQEDVLLWLVEES------NMKENVDRQTILK---ESIQVKLKESISSQT 473
Query: 903 IRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISW---LREPKS 959
I L + ++ ++ K + + + ++K +D +TE D K ++ L+E KS
Sbjct: 474 I-LADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELGNSDLKGNLKEQFPLQELKS 532
Query: 960 KPQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKAT 1019
Q + + + K++ L Q S++ N +K+ K + +I+ K
Sbjct: 533 DAQKEEKIMKHVINENTGQKTQIILGHNQEISEV--KTNEEQKIIKDNQQKKIQKVEKEE 590
Query: 1020 KTKKN---YKDLSNSESECEQ-------EFSHSFKENIPVKEENIHSRMKTVK 1062
++N YKD +Q E S +EN+ ++E+ I+S+ K ++
Sbjct: 591 IQEQNGLLYKDKDTLVISVKQRSLSLTSENSKDVRENVILQEKEIYSKSKEIE 643
Score = 35.4 bits (80), Expect = 0.43
Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 8/96 (8%)
Query: 929 HQKKNLFSDTETEYRCDDSKTDISWLREPK-SKPQLIDYSRNKNVKNHKSGKSRSSLEKG 987
+ K+NL S T++ SW E K S+ L+ + K + K S+ ++
Sbjct: 1498 NDKENLSSSEHTQFNSRSENKTSSWTPESKTSRKSLLKSEKEKKISEEWGFKDISTAQQM 1557
Query: 988 QPSSKMTPSKNITKKMDKTI-------PEGRIRLPR 1016
++ SK + KK+D T+ E ++ LP+
Sbjct: 1558 LKRAQKMKSKKLKKKIDSTVRLALFKNNENKVSLPK 1593
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform 2
[Homo sapiens]
Length = 1336
Score = 43.9 bits (102), Expect = 0.001
Identities = 86/473 (18%), Positives = 185/473 (39%), Gaps = 65/473 (13%)
Query: 617 CWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKEQ 676
CW +E + D +N ++ +K+ K+ K K +E
Sbjct: 209 CWMKQFKVEKKKLENIQKQEQDKMNDELYKEEKIWKE---------------KFKQHEEY 253
Query: 677 TDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKTIEES 736
++ + E K Q++ +KN+ +Q++ V+ + +K+ + +
Sbjct: 254 IRNLHLQMEEERTRFKDQQEK-------EKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPI 306
Query: 737 LIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGKE 796
+ K+ I SK + + + + + E + KQK+ K + KE
Sbjct: 307 I---KEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKE 363
Query: 797 F---TNVAESLISQINKRYK--TKDDIKSTRKLKESLINSGFSNKPVV---------QLS 842
+ N+ + Q+ + K ++D + +L SG++NK + ++
Sbjct: 364 YEEKKNIVKQEREQLISKEKIILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIA 423
Query: 843 KEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRS 902
K V + S +K + + + E N N I+K + Q KE+ + ++
Sbjct: 424 KNLVDENS-KKQEDVLLWLVEES------NMKENVDRQTILK---ESIQVKLKESISSQT 473
Query: 903 IRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISW---LREPKS 959
I L + ++ ++ K + + + ++K +D +TE D K ++ L+E KS
Sbjct: 474 I-LADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELGNSDLKGNLKEQFPLQELKS 532
Query: 960 KPQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKAT 1019
Q + + + K++ L Q S++ N +K+ K + +I+ K
Sbjct: 533 DAQKEEKIMKHVINENTGQKTQIILGHNQEISEV--KTNEEQKIIKDNQQKKIQKVEKEE 590
Query: 1020 KTKKN---YKDLSNSESECEQ-------EFSHSFKENIPVKEENIHSRMKTVK 1062
++N YKD +Q E S +EN+ ++E+ I+S+ K ++
Sbjct: 591 IQEQNGLLYKDKDTLVISVKQRSLSLTSENSKDVRENVILQEKEIYSKSKEIE 643
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 43.5 bits (101), Expect = 0.002
Identities = 81/390 (20%), Positives = 136/390 (34%), Gaps = 43/390 (11%)
Query: 704 GQKNTENAKQSDWPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKN 763
G ++T+ + + P+ + K + E I K K+ + K
Sbjct: 124 GDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKK 183
Query: 764 VQSHRKAEKELTSELNSWDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRK 823
K EK+ E + +QKK + K +E T E + K +T +K +K
Sbjct: 184 ATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTK-KEVKGGKQEKVKQTAAKVKEVQK 242
Query: 824 LKESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPII 883
K V ++K Q R + FV + +L P I
Sbjct: 243 TPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFV------------HGDLKPGQSPAI 290
Query: 884 KLGIQEFQATAKEACADRSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYR 943
+ QA+ + G + E K + +TK K +K+++ +E E
Sbjct: 291 PPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKK------EKEDIKKKSEKETA 344
Query: 944 CDDSKTDISWLREPKSKPQLI--DYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITK 1001
D K + E K I + K+ K S K++ E QP K +
Sbjct: 345 IDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKK------QE 398
Query: 1002 KMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTV 1061
K +K + + P+K + + + +E E+ + S K+ +P K+E KT
Sbjct: 399 KKEKHVEPA--KSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEE-----KTT 451
Query: 1062 KLPKKQQKVFCAETEKELSKQWKNSSLLKD 1091
K E E K K SS+LKD
Sbjct: 452 K---------TVEQEIRKEKSGKTSSILKD 472
Score = 35.0 bits (79), Expect = 0.56
Identities = 87/449 (19%), Positives = 171/449 (38%), Gaps = 66/449 (14%)
Query: 675 EQTDHIKIDKAEV---EVCKKHNQQQNHPKYSGQKNT---ENAKQSDWPVESETTFKSVL 728
E TD +ID+ + E+ K ++Q P+ Q E K + E E K
Sbjct: 126 EDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKAT 185
Query: 729 LNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKM 788
+ IE+ K + + T +K+ +K K EK + +K K++
Sbjct: 186 HKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEK-----VKQTAAKVKEV 240
Query: 789 REK-SKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNK---------PV 838
++ SK KE + ++ +S +++ KD R + + ++ P
Sbjct: 241 QKTPSKPKEKEDKEKAAVS----KHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPT 296
Query: 839 VQLSKEK-----VQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPII---------- 883
Q S+ +++K K K VTSE + + + I
Sbjct: 297 EQASRPTPASPALEEKEGEKKKAE-KKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKA 355
Query: 884 ---KLGIQEFQATA---KEACADRSIRLVGPRNHDELKSSVKTKDKKII----TNHQKKN 933
K G + A A K+ + S + P ++ K + K +K + + ++ +
Sbjct: 356 SETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHS 415
Query: 934 LFSDTETEYRCDDSKTDISWLREPKSKPQLIDYSRNKNV----KNHKSGKSRSSLEKGQP 989
+ SD + + + + +K +I + K+ P + K V + KSGK+ S L+ +P
Sbjct: 416 VPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEP 475
Query: 990 --------SSKMTPSKNITKKMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSH 1041
+ + + TKK +K G+ P+ K + E + ++E
Sbjct: 476 IKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEE---KPEPQIKKEAKP 532
Query: 1042 SFKENIPVKEENIHSRMKTVKLPKKQQKV 1070
+ E + + +++I KTV K ++KV
Sbjct: 533 AISEKVQIHKQDIVKPEKTVSHGKPEEKV 561
Score = 31.6 bits (70), Expect = 6.2
Identities = 46/212 (21%), Positives = 80/212 (37%), Gaps = 27/212 (12%)
Query: 651 TKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTEN 710
TK+K I + + T KKE + + V++ + +++ K +K +
Sbjct: 327 TKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKP 386
Query: 711 AKQSDWPVESETTFKSVLLNKTIEESLIYRKKYILSKD-------------VNTATCDKN 757
A+ VE K K +E + +K++ + D + + K
Sbjct: 387 AE-----VEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKA 441
Query: 758 PSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDD 817
K ++ + E+E+ E + S K +E KGKE V SL K +TK D
Sbjct: 442 VPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKE-EKVPASL---KEKEPETKKD 497
Query: 818 IKSTR-----KLKESLINSGFSNKPVVQLSKE 844
K ++ K K + KP Q+ KE
Sbjct: 498 EKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKE 529
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 42.4 bits (98), Expect = 0.003
Identities = 162/831 (19%), Positives = 323/831 (38%), Gaps = 116/831 (13%)
Query: 783 SKQKKMREKSKGKE-------FTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSN 835
S QK+ EK+ + T + E IS K + K+T K+S+ N
Sbjct: 24 SPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAE-KATSDEKDSVSNIATEI 82
Query: 836 KPVVQLSKEKVQKKSYRKL----KTTFVNVTSEC------------------PVNDVYNF 873
K Q QK+S +K+ K + +N+ + +D +
Sbjct: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
Query: 874 NLNGADDPIIKLGIQ-------EFQATAKEACADRSIRLVGPRNHDELKSSVKTKDKK-- 924
LN A + IK G+Q + QA + S+ + D KS + KK
Sbjct: 143 ALNTATE--IKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPA 200
Query: 925 IITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSKPQLIDYSRNKNVKNHKSG--KSRS 982
+ +K+ FS+ E + + +S + P K + N+ K KSR+
Sbjct: 201 LKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRT 260
Query: 983 SLEKGQPSSKMTPSK-----NIT---KKMDKTIPEGRIRLPR-KATKTKKNYKDLSNSES 1033
+ P K T + NI K +KT + P KAT K++ +E+
Sbjct: 261 VSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATET 320
Query: 1034 ECEQEFSHSFKENIPVKEENIHSRMKTVKLP---KKQQKVFCAETEKELSKQWKNSSLLK 1090
+ EQ + P + + +P K Q+ ++K+ + WK +S+ K
Sbjct: 321 KDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPA--WKATSVKK 378
Query: 1091 DAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPYPK--TSSLES 1148
D++ + ++ + G+ SS EKD + I + I K T S +
Sbjct: 379 DSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSN---IAREIKDGEKSGTVSPQK 435
Query: 1149 LNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTIVNRKKISSLVLT 1208
++ + S N +S + P L + T ++++N + +
Sbjct: 436 QSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLN--TATKMKEV 493
Query: 1209 QETQNSNSYSDVSSYSSEERFMEIES--PHINENYIQSKREESHLASSLSKSSEGREK-- 1264
Q + + +++S ++R E E+ P + +N I S+ + + S SE +
Sbjct: 494 QTSTPAEQDLEMASEGEQKRLEEYENNQPQV-KNQIHSRDDLDDIIQSSQTVSEDGDSLC 552
Query: 1265 ----------TWFDMPC-DATHV--SGPTQHLSRKRIYIEDNLSNSNEVEMEEKGERRAN 1311
+M C D H+ T L ++ I ++DN V++ K + +A+
Sbjct: 553 CNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKI-RKLKNKAS 611
Query: 1312 LLPKKLCKIEDADHHI-HKMSESVSSLSTNDFSIPWETWQNEFAGIEMTYETYERLNSEF 1370
+L K++ + E+ + H++ E L + F+I E + E L+ +
Sbjct: 612 VLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQE---------KKKRRNVEELHQKV 662
Query: 1371 KRRNNIRHKM------LSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIIIEE--- 1421
+ + I + ++ + K+A+ L+T + S +++ + D+ + ++ E
Sbjct: 663 REKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNS--NQVSETDEKEDLLHENRLM 720
Query: 1422 -----LENFEKDSQSLKDLEKEFVDFWEKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCNT 1476
EKD+ ++LEK+++ +E + +K QK+ ++ +LAK++ C +
Sbjct: 721 QDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRN----GETLAKTIACYS 776
Query: 1477 DSEETVFTSEMCLMKEDMKVLQDRLLKDMLEEELLNVRRELMSVFMSHERN 1527
+ T E ++ K+ + R + LE E+ + R L + H+++
Sbjct: 777 -GQLAALTDENTTLRS--KLEKQRESRQRLETEMQSYRCRLNAARCDHDQS 824
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.127 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,110,139
Number of Sequences: 37866
Number of extensions: 2497694
Number of successful extensions: 9370
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 265
Number of HSP's that attempted gapping in prelim test: 8683
Number of HSP's gapped (non-prelim): 931
length of query: 1530
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1415
effective length of database: 13,892,928
effective search space: 19658493120
effective search space used: 19658493120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.