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Search of human proteins with 38348362
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38348362 short-chain dehydrogenase/reductase 10 isoform e
[Homo sapiens]
(315 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Ho... 629 e-180
gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Ho... 438 e-123
gi|38424081 short-chain dehydrogenase/reductase 10 isoform f [Ho... 362 e-100
gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Ho... 265 4e-71
gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Ho... 231 5e-61
gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 194 1e-49
gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 194 1e-49
gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Ho... 171 6e-43
gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo s... 90 2e-18
gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo... 75 8e-14
gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens] 74 2e-13
gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Hom... 72 6e-13
gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A... 71 1e-12
gi|5031737 dehydrogenase/reductase member 2 isoform 2 [Homo sapi... 70 2e-12
gi|33667109 dehydrogenase/reductase member 2 isoform 1 [Homo sap... 70 2e-12
gi|4503817 3-ketodihydrosphingosine reductase precursor [Homo sa... 65 6e-11
gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens] 64 1e-10
gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo... 63 3e-10
gi|22507405 short chain dehydrogenase/reductase family 9C, membe... 62 5e-10
gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens] 59 6e-09
gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens] 58 1e-08
gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo sap... 57 3e-08
gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 57 3e-08
gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 57 3e-08
gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 57 3e-08
gi|4557649 estradiol 17 beta-dehydrogenase 3 [Homo sapiens] 56 4e-08
gi|150247226 retinol dehydrogenase 16 [Homo sapiens] 56 4e-08
gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens] 56 5e-08
gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo... 54 1e-07
gi|146231950 dehydrogenase/reductase (SDR family) member 13 [Hom... 54 1e-07
>gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Homo
sapiens]
Length = 315
Score = 629 bits (1622), Expect = e-180
Identities = 315/315 (100%), Positives = 315/315 (100%)
Query: 1 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA 60
MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA
Sbjct: 1 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA 60
Query: 61 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP 120
HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP
Sbjct: 61 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP 120
Query: 121 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA 180
AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA
Sbjct: 121 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA 180
Query: 181 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQ 240
AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQ
Sbjct: 181 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQ 240
Query: 241 SQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVR 300
SQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVR
Sbjct: 241 SQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVR 300
Query: 301 RLCRGLARPHLFGHD 315
RLCRGLARPHLFGHD
Sbjct: 301 RLCRGLARPHLFGHD 315
>gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Homo
sapiens]
Length = 286
Score = 438 bits (1127), Expect = e-123
Identities = 224/226 (99%), Positives = 224/226 (99%)
Query: 1 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA 60
MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA
Sbjct: 1 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA 60
Query: 61 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP 120
HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP
Sbjct: 61 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP 120
Query: 121 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA 180
AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA
Sbjct: 121 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA 180
Query: 181 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSST 226
AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVR T
Sbjct: 181 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 226
>gi|38424081 short-chain dehydrogenase/reductase 10 isoform f [Homo
sapiens]
Length = 181
Score = 362 bits (929), Expect = e-100
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 135 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 194
MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 1 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
Query: 195 ELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGA 254
ELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGA
Sbjct: 61 ELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGA 120
Query: 255 RTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGH 314
RTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGH
Sbjct: 121 RTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGH 180
Query: 315 D 315
D
Sbjct: 181 D 181
>gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Homo
sapiens]
Length = 199
Score = 265 bits (677), Expect = 4e-71
Identities = 137/139 (98%), Positives = 137/139 (98%)
Query: 88 MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 147
MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS
Sbjct: 1 MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 60
Query: 148 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 207
RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM
Sbjct: 61 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 120
Query: 208 CVLGLRDRASAAEAVRSST 226
CVLGLRDRASAAEAVR T
Sbjct: 121 CVLGLRDRASAAEAVRGVT 139
>gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Homo
sapiens]
Length = 205
Score = 231 bits (590), Expect = 5e-61
Identities = 119/121 (98%), Positives = 119/121 (98%)
Query: 106 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 165
GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS
Sbjct: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 84
Query: 166 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSS 225
LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVR
Sbjct: 85 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 144
Query: 226 T 226
T
Sbjct: 145 T 145
Score = 57.4 bits (137), Expect = 2e-08
Identities = 25/27 (92%), Positives = 25/27 (92%)
Query: 1 MKVLLLTGLGALFFAYYWDDNFDPASL 27
MKVLLLTGLGALFFAYYWDDNFDP L
Sbjct: 1 MKVLLLTGLGALFFAYYWDDNFDPGGL 27
>gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 292
Score = 194 bits (492), Expect = 1e-49
Identities = 111/225 (49%), Positives = 142/225 (63%), Gaps = 4/225 (1%)
Query: 1 MKVLLLTGLGALFFAYYW---DDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLV 57
MK LL LG LF AYY+ ++ F P LQG +V++TGA+ G+G E+AYH A++G+H+V
Sbjct: 4 MKKYLLPILG-LFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVV 62
Query: 58 LTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIG 117
+TA ++ LQKVV +C +LGA YIA M E V A +GGLD L+LNHI
Sbjct: 63 VTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHIT 122
Query: 118 GAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTP 177
R M+VNF+SYV LT ALP L S GS+VVVSSL G+V
Sbjct: 123 NTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAA 182
Query: 178 YSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAV 222
YSA+KFALDGFF S+R+E V VNV+IT+CVLGL D +A +AV
Sbjct: 183 YSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAV 227
>gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 292
Score = 194 bits (492), Expect = 1e-49
Identities = 111/225 (49%), Positives = 142/225 (63%), Gaps = 4/225 (1%)
Query: 1 MKVLLLTGLGALFFAYYW---DDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLV 57
MK LL LG LF AYY+ ++ F P LQG +V++TGA+ G+G E+AYH A++G+H+V
Sbjct: 4 MKKYLLPILG-LFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVV 62
Query: 58 LTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIG 117
+TA ++ LQKVV +C +LGA YIA M E V A +GGLD L+LNHI
Sbjct: 63 VTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHIT 122
Query: 118 GAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTP 177
R M+VNF+SYV LT ALP L S GS+VVVSSL G+V
Sbjct: 123 NTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAA 182
Query: 178 YSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAV 222
YSA+KFALDGFF S+R+E V VNV+IT+CVLGL D +A +AV
Sbjct: 183 YSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAV 227
>gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Homo
sapiens]
Length = 152
Score = 171 bits (434), Expect = 6e-43
Identities = 90/92 (97%), Positives = 90/92 (97%)
Query: 135 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 194
MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 1 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
Query: 195 ELDVQDVNVAITMCVLGLRDRASAAEAVRSST 226
ELDVQDVNVAITMCVLGLRDRASAAEAVR T
Sbjct: 61 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 92
>gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo
sapiens]
Length = 339
Score = 90.1 bits (222), Expect = 2e-18
Identities = 60/181 (33%), Positives = 93/181 (51%), Gaps = 4/181 (2%)
Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPK---VFYIAADM 88
V +TGA++G+GEELAY ++LG LVL+A L++V C + G K + + D+
Sbjct: 53 VWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDL 112
Query: 89 ASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSR 148
+ E+ + L + G +D LV N + S R L+++N++ V LT
Sbjct: 113 TDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKC 172
Query: 149 ALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 207
LP + + K G +V V+S+LG + S Y A+K AL GFF LR EL + +
Sbjct: 173 VLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNI 232
Query: 208 C 208
C
Sbjct: 233 C 233
>gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo
sapiens]
Length = 325
Score = 75.1 bits (183), Expect = 8e-14
Identities = 53/188 (28%), Positives = 94/188 (50%), Gaps = 8/188 (4%)
Query: 25 ASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVV-----GNCRKLGAP 79
A L+ A V++TGA +G+G+E A + G+ LVL L++++ + K+
Sbjct: 48 AYLRNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTH 107
Query: 80 KVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGT-RARSPQATRWLMQVN 138
K + + D+ A + L G +D LV N+ G + GT + + +M+ N
Sbjct: 108 KPYLVTFDLTDSGAIVAAAAEILQCFGYVDILV-NNAGISYRGTIMDTTVDVDKRVMETN 166
Query: 139 FVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELD 197
+ V LT LPS+ + G +V +SS+ G++ F + Y+A+K A FF LR E++
Sbjct: 167 YFGPVALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEME 226
Query: 198 VQDVNVAI 205
++ V +
Sbjct: 227 QYEIEVTV 234
>gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens]
Length = 300
Score = 73.9 bits (180), Expect = 2e-13
Identities = 66/239 (27%), Positives = 105/239 (43%), Gaps = 9/239 (3%)
Query: 26 SLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIA 85
S+ G VL+TGA G+G AY +A+L S LVL + L++ C+ LGA KV
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGA-KVHTFV 91
Query: 86 ADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQL 145
D ++ E S + ++G + LV N + A +VN +++
Sbjct: 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151
Query: 146 TSRALPSLT-DSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 204
T LP++T ++ G +V V+S G V F Y ++KFA GF +L EL +
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 205 ITMCVLGLRDRASAAEAVRSSTSRPRQPEH------RGVPLQSQTAMFLPPTVPGARTL 257
T C+ + +S +PE G+ L Q +F+P ++ TL
Sbjct: 212 KTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGI-LTEQKMIFIPSSIAFLTTL 269
>gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Homo
sapiens]
Length = 311
Score = 72.0 bits (175), Expect = 6e-13
Identities = 58/212 (27%), Positives = 100/212 (47%), Gaps = 10/212 (4%)
Query: 1 MKVLLLTGLGALFFAYYWDDN-FDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLT 59
M LLL G+ L F Y + +++Q V++T A +G+G+E A + G+ LVL
Sbjct: 8 MLPLLLLGISGLLFIYQEVSRLWSKSAVQNKVVVITDAISGLGKECARVFHTGGARLVLC 67
Query: 60 AHTEALLQKV------VGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVL 113
L+ + V + K PK+ + D++ V + LD G +D L+
Sbjct: 68 GKNWERLENLYDALISVADPSKTFTPKL--VLLDLSDISCVPDVAKEVLDCYGCVDILIN 125
Query: 114 NHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPT 172
N S + + +M N+ + LT LP++ + G +V+V+++ G+
Sbjct: 126 NASVKVKGPAHKISLELDKKIMDANYFGPITLTKALLPNMISRRTGQIVLVNNIQGKFGI 185
Query: 173 SFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 204
F T Y+A+K A GFF LR E++ DV ++
Sbjct: 186 PFRTTYAASKHAALGFFDCLRAEVEEYDVVIS 217
>gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A
[Homo sapiens]
Length = 300
Score = 71.2 bits (173), Expect = 1e-12
Identities = 54/186 (29%), Positives = 86/186 (46%), Gaps = 4/186 (2%)
Query: 26 SLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIA 85
S+ G VL+TGA G+G + Y +A+ S LVL + +++ CRKLG Y+
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVV 92
Query: 86 ADMASPEAPESVVQFALDKLGGLDYLVLNHIGGA-PAGTRARSPQATRWLMQVNFVSYVQ 144
E S+ Q + K G +V+N+ G PA + + +VN + +
Sbjct: 93 DCSNREEIYRSLNQ--VKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFW 150
Query: 145 LTSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
+T LPS+ + + G +V V+S+ G + PY ++KFA GF L EL
Sbjct: 151 ITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 204 AITMCV 209
T C+
Sbjct: 211 IKTSCL 216
>gi|5031737 dehydrogenase/reductase member 2 isoform 2 [Homo
sapiens]
Length = 280
Score = 70.1 bits (170), Expect = 2e-12
Identities = 51/175 (29%), Positives = 91/175 (52%), Gaps = 8/175 (4%)
Query: 33 LLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPE 92
++TG+ +G+G +A AR G+H+V+++ + + + + + G V I + E
Sbjct: 40 VVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGL-SVAGIVCHVGKAE 98
Query: 93 APESVVQFALDKLGGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSR 148
E +V AL+ GG+D+LV +N + G+ GT S Q ++ VN S L S+
Sbjct: 99 DREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGT---SEQIWDKILSVNVKSPALLLSQ 155
Query: 149 ALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
LP + + +G++++VSS+ P Y+ +K AL G +L EL +D+ V
Sbjct: 156 LLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRV 210
>gi|33667109 dehydrogenase/reductase member 2 isoform 1 [Homo
sapiens]
Length = 300
Score = 70.1 bits (170), Expect = 2e-12
Identities = 51/175 (29%), Positives = 91/175 (52%), Gaps = 8/175 (4%)
Query: 33 LLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPE 92
++TG+ +G+G +A AR G+H+V+++ + + + + + G V I + E
Sbjct: 40 VVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGL-SVAGIVCHVGKAE 98
Query: 93 APESVVQFALDKLGGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSR 148
E +V AL+ GG+D+LV +N + G+ GT S Q ++ VN S L S+
Sbjct: 99 DREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGT---SEQIWDKILSVNVKSPALLLSQ 155
Query: 149 ALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
LP + + +G++++VSS+ P Y+ +K AL G +L EL +D+ V
Sbjct: 156 LLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRV 210
>gi|4503817 3-ketodihydrosphingosine reductase precursor [Homo
sapiens]
Length = 332
Score = 65.5 bits (158), Expect = 6e-11
Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 9/213 (4%)
Query: 24 PASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALL---QKVVGNCRKLGAPK 80
P +L GA V++TG ++G+G+ +A + G+ + L A E L +K +
Sbjct: 27 PLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQV 86
Query: 81 VFYIAADMASP-EAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQAT-RWLMQVN 138
V I+ D++ E+V++ A +KLG +D LV N G A +G +T LM +N
Sbjct: 87 VLCISVDVSQDYNQVENVIKQAQEKLGPVDMLV-NCAGMAVSGKFEDLEVSTFERLMSIN 145
Query: 139 FVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELD 197
++ V + + ++ + + G +V VSS G++ T YSA+KFA+ G +L +++
Sbjct: 146 YLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEAL--QME 203
Query: 198 VQDVNVAITMCVLGLRDRASAAEAVRSSTSRPR 230
V+ NV IT+ D AE R+ R
Sbjct: 204 VKPYNVYITVAYPPDTDTPGFAEENRTKPLETR 236
>gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]
Length = 311
Score = 64.3 bits (155), Expect = 1e-10
Identities = 56/176 (31%), Positives = 80/176 (45%), Gaps = 21/176 (11%)
Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASP 91
VL++G ++G+G ELA V AH +VV R LG + AA A
Sbjct: 8 VLISGCSSGIGLELA----------VQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALG 57
Query: 92 E----------APESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVS 141
+ + ESV Q G +D LV N G S A + + NF
Sbjct: 58 QTLTVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFG 117
Query: 142 YVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRREL 196
V+L LP + + G +VV+SS++G F+ Y+A+KFAL+GFF SL +L
Sbjct: 118 AVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQL 173
>gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo
sapiens]
Length = 270
Score = 63.2 bits (152), Expect = 3e-10
Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 8/159 (5%)
Query: 29 GARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADM 88
G V++TG G+G + + G+ +V+ E+ G + P +I D+
Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDES-----GGRALEQELPGAVFILCDV 63
Query: 89 ASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRAR--SPQATRWLMQVNFVSYVQLT 146
+ +++V + + G LD V+N+ G P R S Q R L+++N + LT
Sbjct: 64 TQEDDVKTLVSETIRRFGRLD-CVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 147 SRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFAL 185
ALP L S+G+++ +SSL+G + + + PY A K A+
Sbjct: 123 KLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAV 161
>gi|22507405 short chain dehydrogenase/reductase family 9C, member 7
[Homo sapiens]
Length = 313
Score = 62.4 bits (150), Expect = 5e-10
Identities = 60/211 (28%), Positives = 94/211 (44%), Gaps = 23/211 (10%)
Query: 6 LTGLGALFFAYYWDDNFD-PASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEA 64
+ L L F Y W N + +L V +TG ++G G LA G ++ TE
Sbjct: 1 MAALTDLSFMYRWFKNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEE 60
Query: 65 LLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLG--GLDYLVLNHIGGAPAG 122
QK+ ++ + ++ D+ E+ ++ Q+ DK+G GL LV N G P+G
Sbjct: 61 GSQKL----QRDTSYRLQTTLLDVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSG 116
Query: 123 TRARSPQATRWL--------MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSF 174
WL + VN V +++T LP + ++G +V +SS GRV
Sbjct: 117 PN-------EWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAV-I 168
Query: 175 STPYSAAKFALDGFFGSLRRELDVQDVNVAI 205
Y +KF ++ F S+RREL V V I
Sbjct: 169 GGGYCVSKFGVEAFSDSIRRELYYFGVKVCI 199
>gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens]
Length = 309
Score = 58.9 bits (141), Expect = 6e-09
Identities = 52/177 (29%), Positives = 80/177 (45%), Gaps = 5/177 (2%)
Query: 26 SLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIA 85
++ G VL+TGA +G+G LA +ARLGS LVL + ++ R+ GA +V
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYT 96
Query: 86 ADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARS--PQATRWLMQVNFVSYV 143
D + E V ++G + L+ N G G + + VNF +++
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINN--AGIVTGKKFLDCPDELMEKSFDVNFKAHL 154
Query: 144 QLTSRALPS-LTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQ 199
LP+ + + G LV +SS G + Y A+KFA GF S+ E VQ
Sbjct: 155 WTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQ 211
>gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens]
Length = 317
Score = 57.8 bits (138), Expect = 1e-08
Identities = 54/207 (26%), Positives = 97/207 (46%), Gaps = 11/207 (5%)
Query: 4 LLLTGLGALFFAYYWDDNFDPAS-LQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHT 62
L L L++ +W S LQ V +TG ++G G LA G ++ T
Sbjct: 3 LYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLT 62
Query: 63 EALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLG--GLDYLVLNHIGGAP 120
E +++ G + ++ + D+ E+ + Q+ + +G GL LV N+ G
Sbjct: 63 EKGAEQLRGQT----SDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLV-NNAGILT 117
Query: 121 AGTRAR--SPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPY 178
T + + + +++VN + +Q+T LP + ++G +V VSS+LGRV F Y
Sbjct: 118 PITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRV-AFFVGGY 176
Query: 179 SAAKFALDGFFGSLRRELDVQDVNVAI 205
+K+ ++ F LRRE+ V ++I
Sbjct: 177 CVSKYGVEAFSDILRREIQHFGVKISI 203
>gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo
sapiens]
Length = 318
Score = 56.6 bits (135), Expect = 3e-08
Identities = 55/206 (26%), Positives = 99/206 (48%), Gaps = 19/206 (9%)
Query: 9 LGALFFAYYW---DDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEAL 65
LGAL +A W D PAS A V +TG ++G G LA + G ++ + T +
Sbjct: 7 LGALLWAVLWLLRDRQSLPAS--NAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSG 64
Query: 66 LQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALD--KLGGLDYLVLNHIGGAPAGT 123
+ + +++ + ++ D+ P++ + ++ K GL LV N AG
Sbjct: 65 AEDL----QRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNN---AGVAGI 117
Query: 124 RARSPQATR----WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYS 179
+P TR ++ VN + + +T LP L ++G ++ ++S+LGR+ + Y
Sbjct: 118 IGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAAN-GGGYC 176
Query: 180 AAKFALDGFFGSLRRELDVQDVNVAI 205
+KF L+ F SLRR++ + V+I
Sbjct: 177 VSKFGLEAFSDSLRRDVAHFGIRVSI 202
>gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
sapiens]
Length = 343
Score = 56.6 bits (135), Expect = 3e-08
Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASP 91
VL+TG ++G G LA H G + + V L + ++ + ++ S
Sbjct: 58 VLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSS 117
Query: 92 EAPESVVQFALDKLGGLD---YLVLNHIGGAPAG-TRARSPQATRWLMQVNFVSYVQLTS 147
E E VV+ L + + ++N+ G + G S + + + +VN V++T
Sbjct: 118 EEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTK 177
Query: 148 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 205
LP + +KG +V +SS+LGR+ +PY KF ++ F LR E+ V V++
Sbjct: 178 SFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSV 235
>gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
sapiens]
Length = 343
Score = 56.6 bits (135), Expect = 3e-08
Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASP 91
VL+TG ++G G LA H G + + V L + ++ + ++ S
Sbjct: 58 VLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSS 117
Query: 92 EAPESVVQFALDKLGGLD---YLVLNHIGGAPAG-TRARSPQATRWLMQVNFVSYVQLTS 147
E E VV+ L + + ++N+ G + G S + + + +VN V++T
Sbjct: 118 EEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTK 177
Query: 148 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 205
LP + +KG +V +SS+LGR+ +PY KF ++ F LR E+ V V++
Sbjct: 178 SFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSV 235
>gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
sapiens]
Length = 343
Score = 56.6 bits (135), Expect = 3e-08
Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASP 91
VL+TG ++G G LA H G + + V L + ++ + ++ S
Sbjct: 58 VLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSS 117
Query: 92 EAPESVVQFALDKLGGLD---YLVLNHIGGAPAG-TRARSPQATRWLMQVNFVSYVQLTS 147
E E VV+ L + + ++N+ G + G S + + + +VN V++T
Sbjct: 118 EEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTK 177
Query: 148 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 205
LP + +KG +V +SS+LGR+ +PY KF ++ F LR E+ V V++
Sbjct: 178 SFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSV 235
>gi|4557649 estradiol 17 beta-dehydrogenase 3 [Homo sapiens]
Length = 310
Score = 56.2 bits (134), Expect = 4e-08
Identities = 43/182 (23%), Positives = 86/182 (47%), Gaps = 9/182 (4%)
Query: 29 GARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADM 88
G ++TGA G+G+ ++ A+ G ++VL + T L+ + + V I AD
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADF 107
Query: 89 ASPEAPESVVQFALDKLGGLDY-LVLNHIGGAP---AGTRARSPQATRWLMQVNFVSYVQ 144
+ + + +KL GL+ +++N++G P +P + L+ N S V+
Sbjct: 108 TK----DDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 145 LTSRALPSL-TDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
+T L + + KG ++ +SS + P + YSA+K + F +L+ E ++V +
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVII 223
Query: 204 AI 205
+
Sbjct: 224 QV 225
>gi|150247226 retinol dehydrogenase 16 [Homo sapiens]
Length = 317
Score = 56.2 bits (134), Expect = 4e-08
Identities = 52/208 (25%), Positives = 98/208 (47%), Gaps = 8/208 (3%)
Query: 1 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA 60
M + L +G + +++ + + L+ V +TG ++G G+ LA G ++
Sbjct: 1 MWLYLAVFVGLYYLLHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAAC 60
Query: 61 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLG--GLDYLVLNHIGG 118
TE +++ G + ++ + D+ E+ + Q+ + + GL LV N
Sbjct: 61 LTEKGAEQLRGQT----SDRLETVTLDVTKTESVAAAAQWVKECVRDKGLWGLVNNAGIS 116
Query: 119 AP-AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTP 177
P A + Q ++ VN + + +T LP + ++G +V VSS++GRV + F
Sbjct: 117 LPTAPNELLTKQDFVTILDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRV-SLFGGG 175
Query: 178 YSAAKFALDGFFGSLRRELDVQDVNVAI 205
Y +K+ ++ F SLRREL V VA+
Sbjct: 176 YCISKYGVEAFSDSLRRELSYFGVKVAM 203
>gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]
Length = 387
Score = 55.8 bits (133), Expect = 5e-08
Identities = 54/181 (29%), Positives = 79/181 (43%), Gaps = 15/181 (8%)
Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVG--NCRKLGAPKVFYIAADMA 89
VL+TG + G+G L + LG T L + G R+ +P++ + D+
Sbjct: 85 VLVTGGDCGLGHALCKYLDELG----FTVFAGVLNENGPGAEELRRTCSPRLSVLQMDIT 140
Query: 90 SP----EAPESVVQFALDKLGGLDYLVLNHIG--GAPAGTRARSPQATRWLMQVNFVSYV 143
P +A V D+ GL + V+N+ G G P + M VNF V
Sbjct: 141 KPVQIKDAYSKVAAMLQDR--GL-WAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 144 QLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
++T LP L SKG LV VSS+ G P Y ++K A+ F +R EL + V
Sbjct: 198 EVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKV 257
Query: 204 A 204
A
Sbjct: 258 A 258
>gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 54.3 bits (129), Expect = 1e-07
Identities = 44/176 (25%), Positives = 88/176 (50%), Gaps = 8/176 (4%)
Query: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASP 91
+ +TG ++G G A + + G H++ TE+ + + ++ + D+ P
Sbjct: 32 IFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSE----RLRTVLLDVTDP 87
Query: 92 EAPESVVQFALDKLG--GLDYLVLNH-IGGAPAGTRARSPQATRWLMQVNFVSYVQLTSR 148
E + Q+ +++G GL L+ N + G A T + + R ++VN + +T
Sbjct: 88 ENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLN 147
Query: 149 ALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 204
LP + ++G ++ VSS+ GR+ Y+ +K+A++GF SLRR++ V+V+
Sbjct: 148 MLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202
>gi|146231950 dehydrogenase/reductase (SDR family) member 13 [Homo
sapiens]
Length = 377
Score = 54.3 bits (129), Expect = 1e-07
Identities = 51/171 (29%), Positives = 79/171 (46%), Gaps = 12/171 (7%)
Query: 1 MKVLLLTG---LGALFFAYYWDDNFDPA----SLQGARVLLTGANAGVGEELAYHYARLG 53
M+ LLL LGA YY P +L+G ++TGAN+G+G+ A AR G
Sbjct: 1 MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRG 60
Query: 54 SHLVLTAHTEALLQKVVGNCR-KLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLV 112
+ +VL ++ + + R + G +V ++A D+AS + + L LD L+
Sbjct: 61 ARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILI 120
Query: 113 LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVV 163
N A + R+ +A L++VN + LT LP L S VVV
Sbjct: 121 HN----AGISSCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVV 167
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,936,824
Number of Sequences: 37866
Number of extensions: 537355
Number of successful extensions: 1857
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 1750
Number of HSP's gapped (non-prelim): 87
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.