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Search of human proteins with 38158022
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
sapiens]
(1143 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi... 2281 0.0
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 379 e-105
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] 355 1e-97
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi... 352 2e-96
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 350 3e-96
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 348 1e-95
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi... 345 1e-94
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 332 1e-90
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 331 2e-90
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi... 313 6e-85
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 311 3e-84
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 311 3e-84
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 310 4e-84
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po... 272 1e-72
gi|166851804 tudor domain containing 9 [Homo sapiens] 271 3e-72
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 240 5e-63
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom... 229 9e-60
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 219 2e-56
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo... 206 1e-52
gi|38505213 YTH domain containing 2 [Homo sapiens] 200 7e-51
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 157 7e-38
gi|221139761 zinc finger protein 853 [Homo sapiens] 47 1e-04
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 45 5e-04
gi|93204881 Rab interacting lysosomal protein [Homo sapiens] 42 0.003
gi|24307875 zinc finger protein 33B [Homo sapiens] 41 0.007
gi|74027276 zinc finger protein 226 isoform a [Homo sapiens] 40 0.013
gi|74027274 zinc finger protein 226 isoform a [Homo sapiens] 40 0.013
gi|115495000 zinc finger protein 17 [Homo sapiens] 40 0.013
gi|24432013 zinc finger protein 668 [Homo sapiens] 40 0.013
gi|55741659 zinc finger protein 14-like [Homo sapiens] 40 0.017
>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapiens]
Length = 1143
Score = 2281 bits (5912), Expect = 0.0
Identities = 1143/1143 (100%), Positives = 1143/1143 (100%)
Query: 1 MPPPRTREGRDRRDHHRAPSEEEALEKWDWNCPETRRLLEDAFFREEDYIRQGSEECQKF 60
MPPPRTREGRDRRDHHRAPSEEEALEKWDWNCPETRRLLEDAFFREEDYIRQGSEECQKF
Sbjct: 1 MPPPRTREGRDRRDHHRAPSEEEALEKWDWNCPETRRLLEDAFFREEDYIRQGSEECQKF 60
Query: 61 WTFFERLQRFQNLKTSRKEEKDPGQPKHSIPALADLPRTYDPRYRINLSVLGPATRGSQG 120
WTFFERLQRFQNLKTSRKEEKDPGQPKHSIPALADLPRTYDPRYRINLSVLGPATRGSQG
Sbjct: 61 WTFFERLQRFQNLKTSRKEEKDPGQPKHSIPALADLPRTYDPRYRINLSVLGPATRGSQG 120
Query: 121 LGRHLPAERVAEFRRALLHYLDFGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQV 180
LGRHLPAERVAEFRRALLHYLDFGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQV
Sbjct: 121 LGRHLPAERVAEFRRALLHYLDFGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQV 180
Query: 181 VVVAGDTGCGKSTQVPQYLLAAGFSHVACTQPRRIACISLAKRVGFESLSQYGSQVGYQI 240
VVVAGDTGCGKSTQVPQYLLAAGFSHVACTQPRRIACISLAKRVGFESLSQYGSQVGYQI
Sbjct: 181 VVVAGDTGCGKSTQVPQYLLAAGFSHVACTQPRRIACISLAKRVGFESLSQYGSQVGYQI 240
Query: 241 RFESTRSAATKIVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLP 300
RFESTRSAATKIVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLP
Sbjct: 241 RFESTRSAATKIVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLP 300
Query: 301 TRPDLKVILMSATINISLFSSYFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPR 360
TRPDLKVILMSATINISLFSSYFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPR
Sbjct: 301 TRPDLKVILMSATINISLFSSYFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPR 360
Query: 361 PFLRVLESIDHKYPPEERGDLLVFLSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVA 420
PFLRVLESIDHKYPPEERGDLLVFLSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVA
Sbjct: 361 PFLRVLESIDHKYPPEERGDLLVFLSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVA 420
Query: 421 DQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWI 480
DQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWI
Sbjct: 421 DQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWI 480
Query: 481 SQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDP 540
SQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDP
Sbjct: 481 SQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDP 540
Query: 541 RTFPFIEPPPPASLETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFS 600
RTFPFIEPPPPASLETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFS
Sbjct: 541 RTFPFIEPPPPASLETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFS 600
Query: 601 LVEPVLTIAAALSVQSPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERS 660
LVEPVLTIAAALSVQSPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERS
Sbjct: 601 LVEPVLTIAAALSVQSPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERS 660
Query: 661 RNSRKWCRRRGIEEHRLYEMANLRRQFKELLEDHGLLAGAQAAQVGDSYSRLQQRRERRA 720
RNSRKWCRRRGIEEHRLYEMANLRRQFKELLEDHGLLAGAQAAQVGDSYSRLQQRRERRA
Sbjct: 661 RNSRKWCRRRGIEEHRLYEMANLRRQFKELLEDHGLLAGAQAAQVGDSYSRLQQRRERRA 720
Query: 721 LHQLKRQHEEGAGRRRKVLRLQEEQDGGSSDEDRAGPAPPGASDGVDIQDVKFKLRHDLA 780
LHQLKRQHEEGAGRRRKVLRLQEEQDGGSSDEDRAGPAPPGASDGVDIQDVKFKLRHDLA
Sbjct: 721 LHQLKRQHEEGAGRRRKVLRLQEEQDGGSSDEDRAGPAPPGASDGVDIQDVKFKLRHDLA 780
Query: 781 QLQAAASSAQDLSREQLALLKLVLGRGLYPQLAVPDAFNSSRKDSDQIFHTQAKQGAVLH 840
QLQAAASSAQDLSREQLALLKLVLGRGLYPQLAVPDAFNSSRKDSDQIFHTQAKQGAVLH
Sbjct: 781 QLQAAASSAQDLSREQLALLKLVLGRGLYPQLAVPDAFNSSRKDSDQIFHTQAKQGAVLH 840
Query: 841 PTCVFAGSPEVLHAQELEASNCDGSRDDKDKMSSKHQLLSFVSLLETNKPYLVNCVRIPA 900
PTCVFAGSPEVLHAQELEASNCDGSRDDKDKMSSKHQLLSFVSLLETNKPYLVNCVRIPA
Sbjct: 841 PTCVFAGSPEVLHAQELEASNCDGSRDDKDKMSSKHQLLSFVSLLETNKPYLVNCVRIPA 900
Query: 901 LQSLLLFSRSLDTNGDCSRLVADGWLELQLADSESAIRLLAASLRLRARWESALDRQLAH 960
LQSLLLFSRSLDTNGDCSRLVADGWLELQLADSESAIRLLAASLRLRARWESALDRQLAH
Sbjct: 901 LQSLLLFSRSLDTNGDCSRLVADGWLELQLADSESAIRLLAASLRLRARWESALDRQLAH 960
Query: 961 QAQQQLEEEEEDTPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEVQNMYVGPQTIPAT 1020
QAQQQLEEEEEDTPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEVQNMYVGPQTIPAT
Sbjct: 961 QAQQQLEEEEEDTPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEVQNMYVGPQTIPAT 1020
Query: 1021 PHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTNDTDLYSDCLRTFWTCPHCGLHAPLTP 1080
PHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTNDTDLYSDCLRTFWTCPHCGLHAPLTP
Sbjct: 1021 PHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTNDTDLYSDCLRTFWTCPHCGLHAPLTP 1080
Query: 1081 LERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPYHCEACGKDFLFTPTEVLRHRK 1140
LERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPYHCEACGKDFLFTPTEVLRHRK
Sbjct: 1081 LERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPYHCEACGKDFLFTPTEVLRHRK 1140
Query: 1141 QHV 1143
QHV
Sbjct: 1141 QHV 1143
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 379 bits (974), Expect = e-105
Identities = 222/581 (38%), Positives = 335/581 (57%), Gaps = 30/581 (5%)
Query: 144 GQKQAFGRLAKLQ--RERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLA 201
G K ++G+ ++ +R +LPI + +++Q + ++Q+++V G+TG GK+TQ+ QYL
Sbjct: 545 GNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAE 604
Query: 202 AGFSH---VACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVG 258
AG++ + CTQPRR+A +S+AKRV E G +VGY IRFE S T I ++T G
Sbjct: 605 AGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDG 664
Query: 259 LLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISL 318
+LLR+ +P L QY ++++DE HER +H D L G+L++ + R D+K+I+ SAT++
Sbjct: 665 MLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVK 724
Query: 319 FSSYFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEER 378
FS YF AP+ +PGR +P+ ++Y EP T + LD L + I PP
Sbjct: 725 FSQYFYEAPIFTIPGRTYPVEILY---TKEPET---DYLDAS--LITVMQIHLTEPP--- 773
Query: 379 GDLLVFLSGMAEISA----VLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVR 434
GD+LVFL+G EI + E ++ ++LP++SAL Q ++FD APPG R
Sbjct: 774 GDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSR 833
Query: 435 KCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGR 494
K +++TNIAETS+TIDGI +VVD G VK+ Y+ + + +L ISQA A+QR GRAGR
Sbjct: 834 KVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGR 893
Query: 495 TGPGVCFRLYAESDY-DAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPAS 553
TGPG C+RLY E Y D VPEI+R L S VL +K+M + D +F F++ PP +
Sbjct: 894 TGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMET 953
Query: 554 LETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALS 613
L TA+ L GALD LT +G +A+ P++ ++ KMLI+ E +LTI + LS
Sbjct: 954 LITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLS 1013
Query: 614 VQSPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIE 673
VQ+ F R + +GD TL V+N+W + ++ S WC I+
Sbjct: 1014 VQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSW-----KNNKFSNPWCYENFIQ 1068
Query: 674 EHRLYEMANLRRQFKELLEDHGLLAGAQAAQVGDSYSRLQQ 714
L ++R+Q +++ H L G S R+Q+
Sbjct: 1069 ARSLRRAQDIRKQMLGIMDRHKL----DVVSCGKSTVRVQK 1105
>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
Length = 1041
Score = 355 bits (912), Expect = 1e-97
Identities = 209/549 (38%), Positives = 314/549 (57%), Gaps = 28/549 (5%)
Query: 155 LQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSH----VACT 210
+Q R +LP+ + +L + HQV+++ G+TG GK+TQ+PQYL G+++ +ACT
Sbjct: 392 IQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACT 451
Query: 211 QPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPSL 270
QPRR+A +S+A RV E + G++VGY IRFE S T + ++T G+LLR+ EP L
Sbjct: 452 QPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDL 511
Query: 271 PQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSYFSNAPVVQ 330
Y V++VDE HER LH D L G+++ + RP+LKV++ SAT++ + FS++F +APV +
Sbjct: 512 ASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFR 571
Query: 331 VPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRV-LESIDHKYPPEERGDLLVFLSGMA 389
+PGR FP+ + Y +K+ + D +L + S+ + + GD+LVFL+G
Sbjct: 572 IPGRRFPVDIFY---------TKAPEAD---YLEACVVSVLQIHVTQPPGDILVFLTGQE 619
Query: 390 EISAVLEAAQ----TYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAET 445
EI A E Q S + +VLP+++ L Q ++F PPG RK +++TNIAET
Sbjct: 620 EIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAET 679
Query: 446 SVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYA 505
S TI+GI +V+D G K+ SY+P+ ++ L S+ASA QR GRAGR G CFRLY
Sbjct: 680 SPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYT 739
Query: 506 ESDYD-AFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPASLETAILYLRDQ 564
Y VPEI+R +L ++VL +KS+ + D F F++PPP +L + L
Sbjct: 740 AWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYAL 799
Query: 565 GALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSV-QSPFTRSAQ 623
GAL+ LT G +A+LPVD ++ KM++ +S E +LT+AA LSV S F R
Sbjct: 800 GALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKD 859
Query: 624 SSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIEEHRLYEMANL 683
AR GD L NV+ W + S S +WC ++ + ++
Sbjct: 860 KVVHADNARVNFFLPGGDHLVLLNVYTQWAE-----SGYSSQWCCENFVQFRSMRRARDV 914
Query: 684 RRQFKELLE 692
R Q + LLE
Sbjct: 915 REQLEGLLE 923
>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
Length = 1227
Score = 352 bits (902), Expect = 2e-96
Identities = 201/550 (36%), Positives = 302/550 (54%), Gaps = 23/550 (4%)
Query: 149 FGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSH-- 206
F + + +R LPI +L ++++ +V+V G+TG GK+TQ+ QYL G++
Sbjct: 519 FAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYG 578
Query: 207 -VACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQ 265
+ CTQPRR+A +S+AKRV E G +VGY IRFE S T I ++T G+LLR+
Sbjct: 579 MIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESL 638
Query: 266 REPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSYFSN 325
RE L Y +I+DE HER L+ D L G+L+ ++ R DLK+I+ SAT++ F+++F N
Sbjct: 639 READLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGN 698
Query: 326 APVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVFL 385
P+ +PGR FP+ +++ E + K + L GD+L+F+
Sbjct: 699 VPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHL-----------SGAPGDILIFM 747
Query: 386 SGMAEISAVLEAAQTYASHTQR---WVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNI 442
G +I + + + VLP++S L Q K+F AP GVRKCI++TNI
Sbjct: 748 PGQEDIEVTSDQIVEHLEELENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNI 807
Query: 443 AETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFR 502
AETS+T+DGI FV+DSG K ++P+ + LQ + ISQA+A QR GRAGRTGPG CFR
Sbjct: 808 AETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFR 867
Query: 503 LYAESDY-DAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPASLETAILYL 561
LY +S Y + VPEI+R L ++VL +KS+ V D F F++PPP ++ ++ L
Sbjct: 868 LYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQL 927
Query: 562 RDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSPFTRS 621
GALD++ LT G L+ + P+D + KMLI+ +L I + LSV + F R
Sbjct: 928 WILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRP 987
Query: 622 AQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIEEHRLYEMA 681
E R + D T NV+ W + + S WC I + ++
Sbjct: 988 KGREEESDQIREKFAVPESDHLTYLNVYLQW-----KNNNYSTIWCNDHFIHAKAMRKVR 1042
Query: 682 NLRRQFKELL 691
+R Q K+++
Sbjct: 1043 EVRAQLKDIM 1052
>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
sapiens]
Length = 795
Score = 350 bits (899), Expect = 3e-96
Identities = 213/563 (37%), Positives = 306/563 (54%), Gaps = 32/563 (5%)
Query: 151 RLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYL------LAAGF 204
R + ++R LP+ +Y +R L HQ V+ G+TG GK+TQ+PQ+ L
Sbjct: 126 RYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPK 185
Query: 205 SHVACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQI 264
VACTQPRR+A +S+A+RV E G +VGY IRFE SA T + ++T G+LLR+
Sbjct: 186 RGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREA 245
Query: 265 QREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSYFS 324
+P L +Y V+I+DE HER L D L+GVL+ ++ R DLKVI+MSAT++ F YF
Sbjct: 246 MNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFD 305
Query: 325 NAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVF 384
N P++ +PGR P+ + Y P EP E + I EE GDLL+F
Sbjct: 306 NCPLLTIPGRTHPVEIFYTP---EPERDYLE-------AAIRTVIQIHMCEEEEGDLLLF 355
Query: 385 LSGMAEISAVLEAAQTYASHTQRWV----VLPLHSALSVADQDKVFDVAPPGV------R 434
L+G EI + + V ++PL+S L Q ++F+ PP R
Sbjct: 356 LTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGR 415
Query: 435 KCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGR 494
K ++STNIAETS+TIDG+ FV+D G K+ Y+P+ +++ L IS+ASA+QR GRAGR
Sbjct: 416 KVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGR 475
Query: 495 TGPGVCFRLYAESDYDA-FAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPAS 553
T PG CFRLY E Y PEI R L S+VLQ+K + + D F F++PP P +
Sbjct: 476 TRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPET 535
Query: 554 LETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALS 613
L A+ L AL+ LT +GS++A+ P+D + KM+I ++ VL+I A LS
Sbjct: 536 LMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLS 595
Query: 614 VQSPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIE 673
V F R ++ A+ GD TL NV++A+ Q + S +WC I
Sbjct: 596 VPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQ-----NHESVQWCYDNFIN 650
Query: 674 EHRLYEMANLRRQFKELLEDHGL 696
L N+R+Q +++ L
Sbjct: 651 YRSLMSADNVRQQLSRIMDRFNL 673
>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
[Homo sapiens]
Length = 1008
Score = 348 bits (894), Expect = 1e-95
Identities = 220/682 (32%), Positives = 347/682 (50%), Gaps = 79/682 (11%)
Query: 142 DFGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLL- 200
D +K+ R ++Q R LP ++ + HQV V++G+TGCGK+TQV Q++L
Sbjct: 187 DLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILD 246
Query: 201 ------AAGFSHVACTQPRRIACISLAKRVGFESLSQYGS--QVGYQIRFESTRSAAT-K 251
+ CTQPRRI+ IS+A+RV E GS GYQIR +S
Sbjct: 247 NYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGS 306
Query: 252 IVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMS 311
I++ T G++L+ +Q +P L +++DE+HER+L +D L+ V++ LL R DLKVILMS
Sbjct: 307 ILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMS 366
Query: 312 ATINISLFSSYFSNAPVVQVPGRLFPIT----------VVYQPQEAEPTT---------- 351
AT+N FS YF N P++ +PG FP+ + Y P++ E +
Sbjct: 367 ATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGH 426
Query: 352 -SKSEKLDPRPFLR----------------------------------VLESIDHKYPPE 376
++ EK + + ++ I + E
Sbjct: 427 VNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEE 486
Query: 377 ERGDLLVFLSGMAEISAVLEAAQTYASH-TQRWVVLPLHSALSVADQDKVFDVAPPGVRK 435
E G +LVFL G IS + + + + +++++PLHS + +Q +VF PPGVRK
Sbjct: 487 EDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRK 546
Query: 436 CILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT 495
+++TNIAETS+TID + +V+D GK+KE +D Q + + W+S+A+A+QRKGRAGR
Sbjct: 547 IVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRV 606
Query: 496 GPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTF--PFIEPPPPAS 553
PG C+ LY Y +PEI R L+ L LQ+K + +G F ++PP +
Sbjct: 607 QPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEA 666
Query: 554 LETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALS 613
+ +I +L + ALD E LTP+G LA+LPV+ IGKM++ G++F ++PVLTIAA+LS
Sbjct: 667 VLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLS 726
Query: 614 VQSPFTRSAQSSPECAAARRPLESD-QGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGI 672
+ PF A R+ L D + D T+ N F W + + R + +C +
Sbjct: 727 FKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFL 786
Query: 673 EEHRLYEMANLRRQFKELLEDHGLLAGAQAAQVGDSYSRLQQRRER-------RALHQLK 725
+ L + N++ QF E L G ++ D S + E+ L+
Sbjct: 787 SSNTLQMLHNMKGQFAEHLLGAGFVSSRNPK---DPESNINSDNEKIIKAVICAGLYPKV 843
Query: 726 RQHEEGAGRRRKVLRLQEEQDG 747
+ G++RK++++ + DG
Sbjct: 844 AKIRLNLGKKRKMVKVYTKTDG 865
>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo
sapiens]
Length = 707
Score = 345 bits (886), Expect = 1e-94
Identities = 207/551 (37%), Positives = 305/551 (55%), Gaps = 30/551 (5%)
Query: 155 LQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSH---VACTQ 211
++ +R +LPI Q ++L L+ V+ G+TG GK+TQ+PQYL G S +A TQ
Sbjct: 67 VELQRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQGIIAVTQ 126
Query: 212 PRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPSLP 271
PRR+A ISLA RV E ++ G VGY +RF+ S T+I FLT G+LLR+ + L
Sbjct: 127 PRRVAAISLATRVSDEKRTELGKLVGYTVRFDDVTSEDTRIKFLTDGMLLREAISDSLLR 186
Query: 272 QYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDL-----KVILMSATINISLFSSYFSNA 326
+Y +I+DE HER +H D L GV++ R +L KVI+MSAT+++ LFS YF+ A
Sbjct: 187 KYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMDVDLFSQYFNGA 246
Query: 327 PVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVFLS 386
PV+ + GR PI V Y Q + L + I + P + D+LVFL+
Sbjct: 247 PVLYLEGRQHPIQVFYTKQPQNDYLHAA--------LVSVFQIHQEAPSSQ--DILVFLT 296
Query: 387 GMAEISAVLEAAQTYASHTQ----RWVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNI 442
G EI A+ + + A H +VLPL+++L A Q +VF AP G RK I+STNI
Sbjct: 297 GQEEIEAMSKTCRDIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKVIISTNI 356
Query: 443 AETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFR 502
AETS+TI GI++VVD+G VK Y+P + L+ L +S+ A QR GRAGR G+C+R
Sbjct: 357 AETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYR 416
Query: 503 LYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPASLETAILYLR 562
LY E +++ F VPEI+R L S++LQ+ +M V + TF F+ P P ++ AI L
Sbjct: 417 LYTEDEFEKFDKMTVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSKPSPDHIQAAIAQLD 476
Query: 563 DQGAL---DSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSPFT 619
GAL D LTP+G +A P++ K +++ F E +LTI + LSV S
Sbjct: 477 LLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSLLSVDSVLH 536
Query: 620 RSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIEEHRLYE 679
E R+ S +GD TL N++ + + ++ WC+ + +
Sbjct: 537 NPPSRREEVQGVRKKFISSEGDHMTLLNIYRTF-----KNLGGNKDWCKENFVNSKNMTL 591
Query: 680 MANLRRQFKEL 690
+A +R Q +++
Sbjct: 592 VAEVRAQLRDI 602
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
sapiens]
Length = 703
Score = 332 bits (851), Expect = 1e-90
Identities = 204/594 (34%), Positives = 324/594 (54%), Gaps = 42/594 (7%)
Query: 122 GRHLPAERVAEFRRALLHYLDFGQKQAFGRLAKL--QRERAALPIAQYGNRILQTLKEHQ 179
G P ++E R++L + G + A L +++R LP+ + N IL ++ +Q
Sbjct: 14 GTEGPGVSISEERQSLAE--NSGTTVVYNPYAALSIEQQRQKLPVFKLRNHILYLIENYQ 71
Query: 180 VVVVAGDTGCGKSTQVPQYLLAAGFSH----VACTQPRRIACISLAKRVGFESLSQYGSQ 235
VV+ G+TGCGKSTQ+PQYL AG++ V TQPRR+A +++A RV E + G +
Sbjct: 72 TVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHE 131
Query: 236 VGYQIRFES-TRSAATKIVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGV 294
VGY IRF+ T AT+I FLT G+L+R++ +P L +Y V+++DE HER L+ D +G+
Sbjct: 132 VGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGL 191
Query: 295 LQRLLPTRPDLKVILMSATINISLFSSYFSN----------APVVQVPGRLFPITVVYQP 344
L+++ R DL++I+ SAT++ F +F+ ++ V GR FP+ + Y
Sbjct: 192 LKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYL- 250
Query: 345 QEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVFLSGMAEISAV----LEAAQT 400
Q P KS +E++ + E GD+L FL+G E+ V +E A+
Sbjct: 251 QSPVPDYIKS----------TVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARA 300
Query: 401 YA--SHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDS 458
A + VLP+++ L +Q KVF+ VRK I++TN+AETS+TI GI +V+D
Sbjct: 301 LARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDC 360
Query: 459 GKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAPYPVP 518
G VK +Y+P+ ++ L +SQASA QR GR GR+ G C+RLY E +D VP
Sbjct: 361 GFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVP 420
Query: 519 EIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPASLETAILYLRDQGALDSSEALT-PIG 577
E++R L ++LQ+K++ + + F F+ PPP S+ A+ L G LD LT P+G
Sbjct: 421 EMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLG 480
Query: 578 SLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSPFTRSAQSSPECAAARRPLES 637
+A+ P++ + KML+ F + +L+IAA + +Q+ F R
Sbjct: 481 MRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAV 540
Query: 638 DQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIEEHRLYEMANLRRQFKELL 691
++GD T+ N++ A++ + KWC+ + L A +R Q K+LL
Sbjct: 541 EEGDHLTMLNIYEAFI-----KHNKDSKWCQEHFLNYKGLVRAATVREQLKKLL 589
>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
[Homo sapiens]
Length = 994
Score = 331 bits (849), Expect = 2e-90
Identities = 217/681 (31%), Positives = 337/681 (49%), Gaps = 91/681 (13%)
Query: 142 DFGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLL- 200
D +K+ R ++Q R LP ++ + HQV V++G+TGCGK+TQV Q++L
Sbjct: 187 DLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILD 246
Query: 201 ------AAGFSHVACTQPRRIACISLAKRVGFESLSQYGS--QVGYQIRFESTRSAAT-K 251
+ CTQPRRI+ IS+A+RV E GS GYQIR +S
Sbjct: 247 NYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGS 306
Query: 252 IVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMS 311
I++ T G++L+ +Q +P L +++DE+HER+L +D L+ V++ LL R DLKVILMS
Sbjct: 307 ILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMS 366
Query: 312 ATINISLFSSYFSNAPVVQVPGRLFPIT----------VVYQPQEAEPTT---------- 351
AT+N FS YF N P++ +PG FP+ + Y P++ E +
Sbjct: 367 ATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGH 426
Query: 352 -SKSEKLDPRPFLR----------------------------------VLESIDHKYPPE 376
++ EK + + ++ I + E
Sbjct: 427 VNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEE 486
Query: 377 ERGDLLVFLSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKC 436
E G +LVFL G IS + + +L +Q +VF PPGVRK
Sbjct: 487 EDGAILVFLPGWDNISTLHD-------------LLMSQVMFKSVNQTQVFKRTPPGVRKI 533
Query: 437 ILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTG 496
+++TNIAETS+TID + +V+D GK+KE +D Q + + W+S+A+A+QRKGRAGR
Sbjct: 534 VIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQ 593
Query: 497 PGVCFRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTF--PFIEPPPPASL 554
PG C+ LY Y +PEI R L+ L LQ+K + +G F ++PP ++
Sbjct: 594 PGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAV 653
Query: 555 ETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSV 614
+I +L + ALD E LTP+G LA+LPV+ IGKM++ G++F ++PVLTIAA+LS
Sbjct: 654 LLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSF 713
Query: 615 QSPFTRSAQSSPECAAARRPLESD-QGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIE 673
+ PF A R+ L D + D T+ N F W + + R + +C +
Sbjct: 714 KDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLS 773
Query: 674 EHRLYEMANLRRQFKELLEDHGLLAGAQAAQVGDSYSRLQQRRER-------RALHQLKR 726
+ L + N++ QF E L G ++ D S + E+ L+
Sbjct: 774 SNTLQMLHNMKGQFAEHLLGAGFVSSRNPK---DPESNINSDNEKIIKAVICAGLYPKVA 830
Query: 727 QHEEGAGRRRKVLRLQEEQDG 747
+ G++RK++++ + DG
Sbjct: 831 KIRLNLGKKRKMVKVYTKTDG 851
>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo
sapiens]
Length = 779
Score = 313 bits (802), Expect = 6e-85
Identities = 198/598 (33%), Positives = 325/598 (54%), Gaps = 43/598 (7%)
Query: 123 RHLPAERVAEFRRALLHYLDFGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVV 182
R ER + + L + ++ G ++ PI + +I+Q ++++ ++
Sbjct: 14 RQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLI 73
Query: 183 VAGDTGCGKSTQVPQYLLAAGFSH---VACTQPRRIACISLAKRVGFESLSQYGSQVGYQ 239
V G+TG GK+TQ+P+YL AGFS + TQPR++A IS+A+RV E GS+VGYQ
Sbjct: 74 VTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQ 133
Query: 240 IRFESTRSAATKIVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLL 299
+RF+ S T I ++T G LL+ I +P+L ++ V+I+DE HER L D L G+L++L
Sbjct: 134 VRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLF 193
Query: 300 ----PTRPD-LKVILMSATINISLFSSYFSNAPVVQVPGRLFPITVVY----QPQEAEPT 350
P R + LKV++MSAT+ ++ S++F N P+ +PGRL+P+ + P++ E T
Sbjct: 194 QEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENT 253
Query: 351 TSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVFLSGMAEISAVLEAAQTYASHTQR--- 407
++E + E GD+LVFL+G EI E A
Sbjct: 254 AY---------IQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYD 304
Query: 408 --------WVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSG 459
++LP + +++ Q ++F PPG+RKC++STNI+ TS+TIDGIR+VVD G
Sbjct: 305 VQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGG 364
Query: 460 KVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAP-YPVP 518
VK+++++P+ L L+ IS++ A QR GRAGRT G CFR+Y++ ++ P + +P
Sbjct: 365 FVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIP 424
Query: 519 EIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPASLETAILYLRDQGALDSSEALTPIGS 578
EI+R +L S+VL +K +++ D FP+++PP + A+ L A+D S +T +G
Sbjct: 425 EIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGL 484
Query: 579 LLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSPFTR--SAQSSPECAAARRPLE 636
+ + P+ + +I + + +L IAA LSV++ F R + E R L
Sbjct: 485 SMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELA 544
Query: 637 SDQGDPFTLFNVFNAWVQVKSERSRNS---RKWCRRRGIEEHRLYEMANLRRQFKELL 691
+ G FN F A + V E+ ++S WC++ I L+ + Q +EL+
Sbjct: 545 AKAGG----FNDF-ATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELI 597
>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2
[Homo sapiens]
Length = 1155
Score = 311 bits (796), Expect = 3e-84
Identities = 204/572 (35%), Positives = 308/572 (53%), Gaps = 43/572 (7%)
Query: 151 RLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFS----- 205
R + +E LP+ + + IL +++H VVV++GDTGCGK+T++PQ LL +
Sbjct: 384 RRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGA 443
Query: 206 --HVACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTR-SAATKIVFLTVGLLLR 262
+V TQPRRI+ +S+A+RV E VG+Q+R ES S ++F TVG+LLR
Sbjct: 444 RCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLR 503
Query: 263 QIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSY 322
++Q PSL +IVDEVHER ++ DFLL +L+ L P L+++LMSAT + FS Y
Sbjct: 504 KLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRY 563
Query: 323 FSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESID------------ 370
F PV++VPG ++P+ Y E +K K R ES D
Sbjct: 564 FGGCPVIKVPGFMYPVKEHY----LEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDL 619
Query: 371 --HKYPPEERGDLLVFLSGMAEISAVLEAAQ-TYASHTQRWVVLPLHSALSVADQDKVFD 427
H E G +L FL G EI V + Q H ++++LP+HS + + DQ +F
Sbjct: 620 VLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQ 679
Query: 428 VAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQ 487
P GVRK +L+TNIAETS+TI+ I VVDSG KE YD + K+ L+ W+S+A+ Q
Sbjct: 680 QPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQ 739
Query: 488 RKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPF-- 545
R+GRAGR G + L+ S + P+ VPEI R L++LVLQ K + + + F
Sbjct: 740 RRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEKTAVEFLS 798
Query: 546 --IEPPPPASLETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVE 603
++ P +++ A++ L++ G LD E LT +G LA + D + K ++L ++F +
Sbjct: 799 KAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLH 858
Query: 604 PVLTIAAALSVQSPFTRSAQSSPECAAARRPLESDQG-DPFTLFNVFNAWVQVKSERSRN 662
P+L + + L+ + PF+ S Q+ E + L D G D W +V + R+
Sbjct: 859 PLLVVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRS 917
Query: 663 SRKWCRRRGIEEHRLYE-----MANLRRQFKE 689
SR+ +EE+ LY + L +QF E
Sbjct: 918 SRE----NYLEENLLYAPSLRFIHGLIKQFSE 945
>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1
[Homo sapiens]
Length = 1194
Score = 311 bits (796), Expect = 3e-84
Identities = 204/572 (35%), Positives = 308/572 (53%), Gaps = 43/572 (7%)
Query: 151 RLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFS----- 205
R + +E LP+ + + IL +++H VVV++GDTGCGK+T++PQ LL +
Sbjct: 423 RRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGA 482
Query: 206 --HVACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTR-SAATKIVFLTVGLLLR 262
+V TQPRRI+ +S+A+RV E VG+Q+R ES S ++F TVG+LLR
Sbjct: 483 RCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLR 542
Query: 263 QIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSY 322
++Q PSL +IVDEVHER ++ DFLL +L+ L P L+++LMSAT + FS Y
Sbjct: 543 KLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRY 602
Query: 323 FSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESID------------ 370
F PV++VPG ++P+ Y E +K K R ES D
Sbjct: 603 FGGCPVIKVPGFMYPVKEHY----LEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDL 658
Query: 371 --HKYPPEERGDLLVFLSGMAEISAVLEAAQ-TYASHTQRWVVLPLHSALSVADQDKVFD 427
H E G +L FL G EI V + Q H ++++LP+HS + + DQ +F
Sbjct: 659 VLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQ 718
Query: 428 VAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQ 487
P GVRK +L+TNIAETS+TI+ I VVDSG KE YD + K+ L+ W+S+A+ Q
Sbjct: 719 QPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQ 778
Query: 488 RKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPF-- 545
R+GRAGR G + L+ S + P+ VPEI R L++LVLQ K + + + F
Sbjct: 779 RRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEKTAVEFLS 837
Query: 546 --IEPPPPASLETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVE 603
++ P +++ A++ L++ G LD E LT +G LA + D + K ++L ++F +
Sbjct: 838 KAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLH 897
Query: 604 PVLTIAAALSVQSPFTRSAQSSPECAAARRPLESDQG-DPFTLFNVFNAWVQVKSERSRN 662
P+L + + L+ + PF+ S Q+ E + L D G D W +V + R+
Sbjct: 898 PLLVVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRS 956
Query: 663 SRKWCRRRGIEEHRLYE-----MANLRRQFKE 689
SR+ +EE+ LY + L +QF E
Sbjct: 957 SRE----NYLEENLLYAPSLRFIHGLIKQFSE 984
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo
sapiens]
Length = 1270
Score = 310 bits (795), Expect = 4e-84
Identities = 209/614 (34%), Positives = 315/614 (51%), Gaps = 73/614 (11%)
Query: 152 LAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLL-------AAGF 204
L + +ER LP+ ++ + IL+ + ++ VV++ G TGCGK+TQVPQ++L A
Sbjct: 378 LQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAE 437
Query: 205 SHVACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAA-TKIVFLTVGLLLRQ 263
++ TQPRRI+ +S+A+RV FE + G GY +RFES I+F TVG+LLR+
Sbjct: 438 CNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRK 497
Query: 264 IQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSYF 323
+ E + +IVDE+HER ++ DFLL VL+ ++ P+++++LMSATI+ S+F YF
Sbjct: 498 L--EAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYF 555
Query: 324 SNAPVVQVPGRLFPITVVY-----QPQEAEPTTSKSEKLDPR------------------ 360
N P+++V GR +P+ + Q P +K D
Sbjct: 556 FNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDE 615
Query: 361 --PFLRV-LESIDHKYPPEER--------------GDLLVFLSGMAEISAV---LEAAQT 400
P R+ + ++ K P E G +LVFL G I + LE
Sbjct: 616 YGPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPH 675
Query: 401 YASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGK 460
+ SH R+ +LPLHS + +Q KVFD P GV K ILSTNIAETS+TI+ + +V+DS K
Sbjct: 676 FGSH--RYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCK 733
Query: 461 VKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEI 520
K + + W S+ + EQRKGRAGR PG CF L + + ++ + PE+
Sbjct: 734 QKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEM 793
Query: 521 RRVALDSLVLQMKSMSVGDPRTF--PFIEPPPPASLETAILYLRDQGALDSSEALTPIGS 578
R L + L +K + +G F IEPPP ++ A LR+ ALD+++ LTP+G
Sbjct: 794 FRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGR 853
Query: 579 LLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSPFTRSAQSSPECAAARRPLESD 638
+LA+LP++ GKM+I+G +F + + + TIAAA PF + R +
Sbjct: 854 ILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGK---RLGYIHRNFAGN 910
Query: 639 Q-GDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIEEHRLYEMANLRR------QFKELL 691
+ D L +VF AW + ++C EH+ MA LR Q KE+L
Sbjct: 911 RFSDHVALLSVFQAWDDARMGGEEAEIRFC------EHKRLNMATLRMTWEAKVQLKEIL 964
Query: 692 EDHGLLAGAQAAQV 705
+ G QV
Sbjct: 965 INSGFPEDCLLTQV 978
>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
polypeptide 40 [Homo sapiens]
Length = 452
Score = 272 bits (696), Expect = 1e-72
Identities = 159/441 (36%), Positives = 257/441 (58%), Gaps = 33/441 (7%)
Query: 123 RHLPAERVAEFRRALLHYLDFGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVV 182
R ER + + L + ++ G ++ PI + +I+Q ++++ ++
Sbjct: 14 RQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLI 73
Query: 183 VAGDTGCGKSTQVPQYLLAAGFSH---VACTQPRRIACISLAKRVGFESLSQYGSQVGYQ 239
V G+TG GK+TQ+P+YL AGFS + TQPR++A IS+A+RV E GS+VGYQ
Sbjct: 74 VTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQ 133
Query: 240 IRFESTRSAATKIVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLL 299
+RF+ S T I ++T G LL+ I +P+L ++ V+I+DE HER L D L G+L++L
Sbjct: 134 VRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLF 193
Query: 300 ----PTRPD-LKVILMSATINISLFSSYFSNAPVVQVPGRLFPITVVY----QPQEAEPT 350
P R + LKV++MSAT+ ++ S++F N P+ +PGRL+P+ + P++ E T
Sbjct: 194 QEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENT 253
Query: 351 TSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVFLSGMAEISAVLEAAQTYASHTQR--- 407
+ ++V I + E GD+LVFL+G EI E A
Sbjct: 254 AYI------QAIVKVTMDI---HLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYD 304
Query: 408 --------WVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSG 459
++LP + +++ Q ++F PPG+RKC++STNI+ TS+TIDGIR+VVD G
Sbjct: 305 VQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGG 364
Query: 460 KVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAP-YPVP 518
VK+++++P+ L L+ IS++ A QR GRAGRT G CFR+Y++ ++ P + +P
Sbjct: 365 FVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIP 424
Query: 519 EIRRVALDSLVLQMKSMSVGD 539
EI+R +L S+VL +K +++ D
Sbjct: 425 EIKRTSLTSVVLTLKCLAIHD 445
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 271 bits (693), Expect = 3e-72
Identities = 189/604 (31%), Positives = 303/604 (50%), Gaps = 59/604 (9%)
Query: 162 LPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLL-----AAGFSHVACTQPRRIA 216
LPI++Y ++ ++ + VV++ G TG GKSTQ+PQY+L + + + TQPR+I
Sbjct: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYCSIVVTQPRKIG 191
Query: 217 CISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPSLPQYEVL 276
S+A+ + E G VGYQ+ E + T+++++T G+LL++I SL ++ +
Sbjct: 192 ASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTHI 251
Query: 277 IVDEVHERHLHNDFLLGVLQRLLPTRPD-LKVILMSATINISLFSSYFSNAPVVQVPGRL 335
I+DEVHER DFLL V+++LL T +KV+LMSATI+ F+ YF+ PV
Sbjct: 252 IIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFA-VPVQNKMNPA 310
Query: 336 FPITVVYQPQEAEPTTSKS------EKLDPR----------------PFLRVLESIDHKY 373
+ V +P E KL P +++ + +D K
Sbjct: 311 YIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLIQMFDDLDMKE 370
Query: 374 PPE----------ERGDLLVFLSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVADQD 423
ER +LVFL G+ EI+ + E + +R V PLHS++++ +Q+
Sbjct: 371 SGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVH--KRLQVYPLHSSVALEEQN 428
Query: 424 KVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQA 483
VF PG RK ILSTNIAE+SVT+ +++V+D + + D Q L+ W S+
Sbjct: 429 NVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKT 488
Query: 484 SAEQRKGRAGRTGPGVCFRLYAESDYDAFAP-YPVPEIRRVALDSLVLQMKSMSVGDPRT 542
S QRKGRAGR G C+RL + +D P + VPE+ R L S +L++K + +G+PR
Sbjct: 489 SCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRA 548
Query: 543 F--PFIEPPPPASLETAILYLRDQGALDSS----------EALTPIGSLLAQLPVDVVIG 590
+ PP + +E IL L++ GAL S LT +G +LAQLPV+ +G
Sbjct: 549 LLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQQLG 608
Query: 591 KMLILGSMFSLVEPVLTIAAALSVQSPFTRSAQSSPECAAARRPLE-SDQGDPFTLFNVF 649
K+++LG +F ++ L IAAALS+++ F + + + S + D L F
Sbjct: 609 KLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKSDCIALVEAF 668
Query: 650 NAWVQVKS----ERSRNSRKWCRRRGIEEHRLYEMANLRRQFKELLEDHGLLAGAQAAQV 705
W + ++ W R I+ R+ E+A L + K + + ++ +
Sbjct: 669 KTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNMHVDSRRPVM 728
Query: 706 GDSY 709
Y
Sbjct: 729 DQEY 732
>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
Length = 1386
Score = 240 bits (613), Expect = 5e-63
Identities = 141/335 (42%), Positives = 191/335 (57%), Gaps = 13/335 (3%)
Query: 371 HKYPPEERGDLLVFLSGMAEISAVLEAAQTYA----SHTQRWVVLPLHSALSVADQDKVF 426
H YPP G +LVFL G+AEI + E Q+ + + R V+ PLHS+LS +Q VF
Sbjct: 843 HSYPP---GAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVF 899
Query: 427 DVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAE 486
P GV K I+STNIAETS+TID + +V+DSGK+KE YD ++ L++ ++SQA+A
Sbjct: 900 VKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANAL 959
Query: 487 QRKGRAGRTGPGVCFRLYAESDYD-AFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFP- 544
QRKGRAGR GVCF L+ Y+ +PEI+RV L+ L L++K + +
Sbjct: 960 QRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQS 1019
Query: 545 ----FIEPPPPASLETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFS 600
IEPP SL + + LRD GAL E LTP+G LA LPVDV IGK+++ GS+F
Sbjct: 1020 VFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFR 1079
Query: 601 LVEPVLTIAAALSVQSPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERS 660
++P LTIAA+L+ +SPF E + D L + W E
Sbjct: 1080 CLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGV 1139
Query: 661 RNSRKWCRRRGIEEHRLYEMANLRRQFKELLEDHG 695
R S +CR+ + L EMA+L+RQF ELL D G
Sbjct: 1140 RASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIG 1174
Score = 188 bits (477), Expect = 3e-47
Identities = 100/234 (42%), Positives = 151/234 (64%), Gaps = 9/234 (3%)
Query: 143 FGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAA 202
F KQA + + +ER +LP + IL L++HQVVV++G TGCGK+TQ+PQ++L
Sbjct: 525 FRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDD 584
Query: 203 GFS-------HVACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFL 255
+ ++ CTQPRRI+ IS+A+RV E + G VGYQIR ES +S+AT++++
Sbjct: 585 SLNGPPEKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYC 644
Query: 256 TVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATIN 315
T G+LLR+++ + +L +IVDEVHER +DFLL VL+ ++ RP L+VILMSAT+N
Sbjct: 645 TTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLN 704
Query: 316 ISLFSSYFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESI 369
LFS YF++ PV+ +PGR FP+ + E ++ D P++R ++ I
Sbjct: 705 AELFSDYFNSCPVITIPGRTFPVDQFF--LEDAIAVTRYVLQDGSPYMRSMKQI 756
>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
sapiens]
Length = 743
Score = 229 bits (585), Expect = 9e-60
Identities = 168/534 (31%), Positives = 267/534 (50%), Gaps = 28/534 (5%)
Query: 151 RLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQ----YLLAAGFSH 206
R KL +ER LPI + ++ L ++Q+V+V+GD CGKS QVPQ Y L+ + H
Sbjct: 51 RYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQH 110
Query: 207 --VACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQI 264
V CTQ + + LA RV E G +VGY I FE+ + T + + T +L R++
Sbjct: 111 GGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREM 170
Query: 265 QREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSYFS 324
P L Y V+I+D++HER + D LLG+L+ +L RP+LK+I+ S+ IS +SY+
Sbjct: 171 MSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYG 230
Query: 325 NAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVF 384
N PV++V + P+ VVY S+++K LR++ I H E+GD++VF
Sbjct: 231 NVPVIEVKNK-HPVEVVY--------LSEAQKDSFESILRLIFEIHHS---GEKGDIVVF 278
Query: 385 LSGMAEISAVLEAAQTYAS---HTQRWVVLPLHSALSVA---DQDKVFDVAPPGVRKCIL 438
L+ +I V E ++ VV+PL+ + D+ R+ +L
Sbjct: 279 LACEQDIEKVCETVYQGSNLNPDLGELVVVPLYPKEKCSLFKPLDETEKRCQVYQRRVVL 338
Query: 439 STNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPG 498
+T+ E + + +RFV+D G + Y+P+ + L ISQ+ AE RK G + G
Sbjct: 339 TTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSG 398
Query: 499 VCFRLYAESDYDA-FAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPASLETA 557
F LY E P E++ L S+VL MK + + F+ P P SL A
Sbjct: 399 KFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRPAPESLMQA 458
Query: 558 ILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSP 617
+ L ALD+ L+ G ++++ P+D + K ++ F V+ VLTIAA ++ +
Sbjct: 459 LEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNC 518
Query: 618 FTRSAQSSPECA-AARRPLESDQGDPFTLFNVFNAW--VQVKSERSRNSRKWCR 668
F+ + E A + +GD FTL +++ A+ + S KWCR
Sbjct: 519 FSHVPHGAEEAALTCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYCVEKWCR 572
>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
Length = 1369
Score = 219 bits (557), Expect = 2e-56
Identities = 121/322 (37%), Positives = 188/322 (58%), Gaps = 5/322 (1%)
Query: 379 GDLLVFLSGMAEISAVLEA-AQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCI 437
G +L+FL G+A I + + + +++R+ V+ LHS LS DQ F + PPGVRK +
Sbjct: 868 GAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIV 927
Query: 438 LSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGP 497
L+TNIAET +TI + FV+D+G+ KE Y +++ L E ++S+ASA QR+GRAGR
Sbjct: 928 LATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRD 987
Query: 498 GVCFRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTF--PFIEPPPPASLE 555
G CFR+Y ++ F Y VPEI RV L+ L L + ++G P F ++PP +
Sbjct: 988 GFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVIS 1047
Query: 556 TAILYLRDQGALDSSE-ALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSV 614
A+ LR GA + +E LTP+G LA LPV+V IGKMLI G++F ++PV T+AA ++
Sbjct: 1048 NAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTE 1107
Query: 615 QSPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERS-RNSRKWCRRRGIE 673
+SPFT E A+ L D T++N + W + + E R+ +CRR +
Sbjct: 1108 KSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLN 1167
Query: 674 EHRLYEMANLRRQFKELLEDHG 695
L + +++++ +L++ G
Sbjct: 1168 RTSLLTLEDVKQELIKLVKAAG 1189
Score = 173 bits (438), Expect = 1e-42
Identities = 97/227 (42%), Positives = 143/227 (62%), Gaps = 13/227 (5%)
Query: 143 FGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLA- 201
F + Q+ + KL +ER LP+ ++ + I++TLK H+VVVVAG+TG GKSTQVP +LL
Sbjct: 553 FRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLED 612
Query: 202 -------AGFSHVACTQPRRIACISLAKRVGFESLSQYG-----SQVGYQIRFESTRSAA 249
A ++ CTQPRRI+ +SLA RV E + G S GYQIR ES +
Sbjct: 613 LLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACES 672
Query: 250 TKIVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVIL 309
T++++ T G+LLR++Q + L +IVDEVHER + +DFLL +L+ +L R DL +IL
Sbjct: 673 TRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLIL 732
Query: 310 MSATINISLFSSYFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEK 356
MSAT++ FS+YF++ P++++ GR +P+ V + E T EK
Sbjct: 733 MSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEK 779
>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
sapiens]
Length = 717
Score = 206 bits (523), Expect = 1e-52
Identities = 173/557 (31%), Positives = 269/557 (48%), Gaps = 34/557 (6%)
Query: 151 RLAKLQRERAALPIAQYGNRILQTLKEHQ--VVVVAGDTGCGKSTQVPQ----YLLAAGF 204
R +L ++R ALPI L+ L+ + VV+V+G+ G GKSTQ+PQ + LA GF
Sbjct: 34 RYYELLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGF 93
Query: 205 S--HVACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLR 262
V TQP +A SLA RV E G +VGY I E T + F LLL+
Sbjct: 94 QKGQVTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRLLLQ 153
Query: 263 QIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQ--RLLPTRPDLKVILMSATINISLFS 320
++ + VL++DE ER + +D L G+LQ RL DL+V++++
Sbjct: 154 EVASTRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEPKLR 213
Query: 321 SYFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEERGD 380
+++ N P+V +P +P E P+ + + P +++ E GD
Sbjct: 214 AFWGNPPIVHIPR---------EPGE-RPSPIYWDTIPPDRVEAACQAVLELCRKELPGD 263
Query: 381 LLVFLSGMAEISAVLEA----AQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKC 436
+LVFL EIS E+ ++ VLPLH A Q D+ RK
Sbjct: 264 VLVFLPSEEEISLCCESLSREVESLLLQGLPPRVLPLHPDCGRAVQAVYEDM---DARKV 320
Query: 437 ILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTG 496
+++ +A+ S ++ I+ V+DSG Y+P+ + + IS+ AE R+ RA
Sbjct: 321 VVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGFP 380
Query: 497 PGVCFRLYAESDYDAFAP-YPVPEIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPASLE 555
PG C LY +S + AP P P + L SLVL +K + +P F++ P P +L
Sbjct: 381 PGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFLDQPAPEALM 440
Query: 556 TAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQ 615
A+ L ALD L+ +G +L++ P+ + K L+ F V+ +LT+AA L+
Sbjct: 441 QALEDLDYLAALDDDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAA 500
Query: 616 SPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIEEH 675
FTR S+ E AA RR LE GD +L V+ A++Q ++ + WC+ RG+
Sbjct: 501 PGFTRPPLSAEE-AALRRALEHTDGDHSSLIQVYEAFIQSGADEA-----WCQARGLNWA 554
Query: 676 RLYEMANLRRQFKELLE 692
L + LR + EL++
Sbjct: 555 ALCQAHKLRGELLELMQ 571
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 200 bits (508), Expect = 7e-51
Identities = 127/364 (34%), Positives = 192/364 (52%), Gaps = 16/364 (4%)
Query: 355 EKLDPRPFLRVLESIDHKYPPEERGDLLVFLSGMAEI----SAVLEAAQTYASHTQRWVV 410
EK+D + +L +I H + G +L+FL G EI +L + +A +T R+ V
Sbjct: 602 EKVDLDLIMHLLYNICHSC---DAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQV 658
Query: 411 LPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQA 470
LHS + +DQ KV P GVRK ILSTNIAETS+T++ + FV+DSGKVKE S+D
Sbjct: 659 FMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALN 718
Query: 471 KLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLVL 530
+ L+ WIS+ASA QRKGRAGR PG+CFRL++ + + PE+ R+ L L L
Sbjct: 719 FVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCL 778
Query: 531 QMKSMSVGDPRTFPFI----EPPPPASLETAILYLRDQGALDSSEALTPIGSLLAQLPVD 586
K ++ + F+ EPPP + A+ L+ A+D+ E LT +G LA LPV+
Sbjct: 779 HTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVE 838
Query: 587 VVIGKMLILGSMFSLVEPVLTIAAALSVQSPFTRSAQSSPECAA---ARRPLESDQGDPF 643
+GKM++ + ++P+LTIA L+ + PF Q+S + AA +R D
Sbjct: 839 PHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHM 898
Query: 644 TLFNVFNAWVQVKSERSRNSRKWCRRRGIEEHRLYEMANLRRQFKELLEDHGLLAGAQAA 703
L F AW + +S+ R +C + + + + + +R Q L G +
Sbjct: 899 ALLRAFQAWQKARSDGW--ERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGG 956
Query: 704 QVGD 707
+ D
Sbjct: 957 DIRD 960
Score = 149 bits (375), Expect = 2e-35
Identities = 80/190 (42%), Positives = 121/190 (63%), Gaps = 6/190 (3%)
Query: 159 RAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSH-----VACTQPR 213
R +LP+ + I++ +KE++VV++ G+TG GK+TQ+PQ+LL F + + CTQPR
Sbjct: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPR 249
Query: 214 RIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQR-EPSLPQ 272
R+A I++A+RV E + G +GYQIR ES S T + F T G+LLR + + +L
Sbjct: 250 RLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLST 309
Query: 273 YEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSYFSNAPVVQVP 332
+IVDEVHER +DFLL L+ LL P LK+IL SA ++++LF YF + PV+ +
Sbjct: 310 VTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQ 369
Query: 333 GRLFPITVVY 342
GR F + ++
Sbjct: 370 GRPFEVKEMF 379
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo
sapiens]
Length = 1157
Score = 157 bits (396), Expect = 7e-38
Identities = 97/257 (37%), Positives = 155/257 (60%), Gaps = 25/257 (9%)
Query: 151 RLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSH---- 206
R ++Q ER LPI I++ + EH +V+V G+TG GK+TQVPQ+L AGFS
Sbjct: 241 RSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSI 300
Query: 207 VACTQPRRIACISLAKRVGFE-SLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQ 265
+ T+PRR+A +++++RV E +LSQ V YQIR+E + T+I F+T G+LL++IQ
Sbjct: 301 IGVTEPRRVAAVAMSQRVAKEMNLSQ--RVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQ 358
Query: 266 REPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRP----DLKVILMSATINISLFSS 321
++ L +Y+V+I+DE HER ++ D L+G+L R++ R LK+++MSAT+ + F+
Sbjct: 359 KDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQ 418
Query: 322 ----YFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEE 377
+ PV++V R FP+TV + + + E F +V + H+ P
Sbjct: 419 NPRLFAKPPPVIKVESRQFPVTVHFNKR------TPLEDYSGECFRKVCKI--HRMLP-- 468
Query: 378 RGDLLVFLSGMAEISAV 394
G +LVFL+G AE+ A+
Sbjct: 469 AGGILVFLTGQAEVHAL 485
Score = 154 bits (390), Expect = 4e-37
Identities = 89/224 (39%), Positives = 126/224 (56%), Gaps = 15/224 (6%)
Query: 410 VLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQ 469
VLPL+S L+ Q +VF P G R C+++TN+AETS+TI GI++VVD GKVK+ YD
Sbjct: 590 VLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRV 649
Query: 470 AKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLV 529
+ + W+SQASA+QR GRAGRT PG C+RLY+ + + F +P PEI R ++ L+
Sbjct: 650 TGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLI 709
Query: 530 LQMKSMSVGDPRTFPFIEPPPPASLETAILYLRDQGALDSSE---------------ALT 574
LQMK+++V FPF PP +L A L GAL + +T
Sbjct: 710 LQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPIT 769
Query: 575 PIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSPF 618
+G +A PV KML L + +TI A+++V+ F
Sbjct: 770 ALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELF 813
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 47.0 bits (110), Expect = 1e-04
Identities = 64/237 (27%), Positives = 94/237 (39%), Gaps = 40/237 (16%)
Query: 944 LRLRARWESALDRQLAHQAQQQLEEEEEDTPVSPKEVATLSKEL-LQFTASKIPYSLRRL 1002
L+L+ + E Q Q QQQLE++E ++P E+ +E+ L+ T + L +
Sbjct: 357 LQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELV 416
Query: 1003 TG----------------------LEVQNMYVGPQTI-PATPHLPGLFGSSTLSPHPTKG 1039
+ VQ + V P PA +PG GS+ L+P +
Sbjct: 417 PAAGGGGAAVPGAPAAVVVAPPGYVVVQELMVLPAVAAPAVVAIPGPAGSAALTPARQRR 476
Query: 1040 GYAVTDFLTY--NC---LTNDTDLYSDCLRTFWTCPH----CGL----HAPLTPLERIAH 1086
D T C + TDL PH CG H+ L +RI H
Sbjct: 477 RRRARDRPTICGECGKGFSRSTDLVRHQATHTGERPHRCGECGKGFSQHSNLVTHQRI-H 535
Query: 1087 ENTCPQA-PQDGPPGAEEAALETLQKTSVLQRPYHCEACGKDFLFTPTEVLRHRKQH 1142
P A +E +AL Q+T +RPY C CGK F + + +LRHR+ H
Sbjct: 536 TGEKPYACSYCAKRFSESSALVQHQRTHTGERPYACGDCGKRFSVS-SNLLRHRRTH 591
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 44.7 bits (104), Expect = 5e-04
Identities = 54/248 (21%), Positives = 109/248 (43%), Gaps = 26/248 (10%)
Query: 217 CISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQ----REPSLPQ 272
C +K +G + YG + E R A +I+ T G ++ + R +L +
Sbjct: 465 CKKFSKTLGLRVVCVYGGTGISEQIAELKRGA--EIIVCTPGRMIDMLAANSGRVTNLRR 522
Query: 273 YEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISL--FSSYFSNAPV-V 329
+++DE +R F V++ + RPD + ++ SAT ++ + + P+ V
Sbjct: 523 VTYVVLDEA-DRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEV 581
Query: 330 QVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVFLSGMA 389
QV GR +VV E + + EK FL++LE + H +E G +++F+
Sbjct: 582 QVGGR----SVVCSDVEQQVIVIEEEK----KFLKLLELLGHY---QESGSVIIFVDKQE 630
Query: 390 EISAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTI 449
+L+ + + + LH + D+D + + G K +++T++A + +
Sbjct: 631 HADGLLKDLMRAS-----YPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDV 685
Query: 450 DGIRFVVD 457
+ VV+
Sbjct: 686 KHLILVVN 693
>gi|93204881 Rab interacting lysosomal protein [Homo sapiens]
Length = 401
Score = 42.4 bits (98), Expect = 0.003
Identities = 59/233 (25%), Positives = 94/233 (40%), Gaps = 30/233 (12%)
Query: 689 ELLEDHGLLAGAQAAQVGDSYSRLQQRRERRALHQLKRQHEEGAGRRRKVLRLQEEQDGG 748
ELLE + + QV + + RR R +L+R+ G R +LR +E
Sbjct: 63 ELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDR 122
Query: 749 SSDEDRA--------GPAPPGASDGVD-IQDVKFKLRHDLAQLQAAASSAQDLSREQLAL 799
DE RA G + + + V +LRH LA +Q +AQD RE
Sbjct: 123 QRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERE---- 178
Query: 800 LKLVLGRGLYPQLAVPDAFNSSRKDSDQIFHTQAKQGAVLHPTCVFAGSPE--VLHAQEL 857
R + A P A +R + + H ++ G+PE AQ+L
Sbjct: 179 ------RQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQL 232
Query: 858 ----EASNCDGSRDDKDK-MSSKHQLLSFVSLLETNKPY----LVNCVRIPAL 901
EA C SR++ ++ + +++L + V LL+ Y L+ R+P L
Sbjct: 233 GRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGL 285
>gi|24307875 zinc finger protein 33B [Homo sapiens]
Length = 778
Score = 40.8 bits (94), Expect = 0.007
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 7/83 (8%)
Query: 1060 SDCLRTFWTCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPY 1119
+ C +TFW + H E+ N C G + ++AL Q+T ++PY
Sbjct: 360 NQCGKTFWEKSNLTKHQRSHTGEKPFECNEC------GKAFSHKSALTLHQRTHTGEKPY 413
Query: 1120 HCEACGKDFLFTPTEVLRHRKQH 1142
C ACGK F + +++ +H++ H
Sbjct: 414 QCNACGKTF-YQKSDLTKHQRTH 435
Score = 35.0 bits (79), Expect = 0.41
Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 4/78 (5%)
Query: 1067 WTCPHCGL----HAPLTPLERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPYHCE 1122
+ C CG + LT +RI + + G ++AL Q+T ++PY C
Sbjct: 609 YECNECGKTFCQKSQLTQHQRIHIGEKPYECNECGKAFCHKSALIVHQRTHTQEKPYKCN 668
Query: 1123 ACGKDFLFTPTEVLRHRK 1140
CGK F +L RK
Sbjct: 669 ECGKSFCVKSGLILHERK 686
Score = 32.7 bits (73), Expect = 2.0
Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 1067 WTCPHCG----LHAPLTPLERIAHENTCP-QAPQDGPPGAEEAALETLQKTSVLQRPYHC 1121
+ C CG +++ LT +R H P + + G +++ L Q+T + +PY C
Sbjct: 441 YECYECGKSFCMNSHLTVHQR-THTGEKPFECLECGKSFCQKSHLTQHQRTHIGDKPYEC 499
Query: 1122 EACGKDFLFTPTEVLRHRKQH 1142
ACGK F + + + RH+ H
Sbjct: 500 NACGKTF-YHKSVLTRHQIIH 519
Score = 32.3 bits (72), Expect = 2.6
Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 7/83 (8%)
Query: 1060 SDCLRTFWTCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPY 1119
++C + FW H H + E+ N C G E++ L Q++ ++P+
Sbjct: 332 NECGKAFWEKSHLTRHQRVHTGEKHFQCNQC------GKTFWEKSNLTKHQRSHTGEKPF 385
Query: 1120 HCEACGKDFLFTPTEVLRHRKQH 1142
C CGK F L H++ H
Sbjct: 386 ECNECGKAFSHKSALTL-HQRTH 407
Score = 32.3 bits (72), Expect = 2.6
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 7/81 (8%)
Query: 1067 WTCPHCG----LHAPLTPLERIAHENTCPQA-PQDGPPGAEEAALETLQKTSVLQRPYHC 1121
+ C CG L + LT +R H P A P+ G + ++ L +T ++PY C
Sbjct: 525 YECYECGKTFCLKSDLTIHQR-THTGEKPFACPECGKFFSHKSTLSQHYRTHTGEKPYEC 583
Query: 1122 EACGKDFLFTPTEVLRHRKQH 1142
CGK F + + + +H + H
Sbjct: 584 HECGKIF-YNKSYLTKHNRTH 603
Score = 32.0 bits (71), Expect = 3.5
Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 5/78 (6%)
Query: 1069 CPHCGL---HAPLTPLERIAHENTCP-QAPQDGPPGAEEAALETLQKTSVLQRPYHCEAC 1124
C CG H L + H P Q G +++ L Q+T Q+PY C C
Sbjct: 387 CNECGKAFSHKSALTLHQRTHTGEKPYQCNACGKTFYQKSDLTKHQRTHTGQKPYECYEC 446
Query: 1125 GKDFLFTPTEVLRHRKQH 1142
GK F + + H++ H
Sbjct: 447 GKSFCMN-SHLTVHQRTH 463
>gi|74027276 zinc finger protein 226 isoform a [Homo sapiens]
Length = 803
Score = 40.0 bits (92), Expect = 0.013
Identities = 17/54 (31%), Positives = 31/54 (57%)
Query: 1075 HAPLTPLERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPYHCEACGKDF 1128
++P+ P+ + H + + G ++ A L+T QK V+++PY C+ CGK F
Sbjct: 291 YSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGF 344
Score = 33.5 bits (75), Expect = 1.2
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 15/94 (15%)
Query: 1049 YNCLTNDTDLYSDCLRTFWTCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGAEEAALET 1108
YNC +C R F H H L E+ + C G + + L++
Sbjct: 363 YNC--------EECGRAFSQASHLQDHQRLHTGEKPFKCDAC------GKSFSRNSHLQS 408
Query: 1109 LQKTSVLQRPYHCEACGKDFLFTPTEVLRHRKQH 1142
Q+ ++PY CE CGK F+ + + + H++ H
Sbjct: 409 HQRVHTGEKPYKCEECGKGFICS-SNLYIHQRVH 441
Score = 33.5 bits (75), Expect = 1.2
Identities = 20/77 (25%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 1067 WTCPHCGLH---APLTPLERIAHENTCP-QAPQDGPPGAEEAALETLQKTSVLQRPYHCE 1122
+ C CG + A L + H P + G + + L++ Q+ ++PY CE
Sbjct: 699 YKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCE 758
Query: 1123 ACGKDFLFTPTEVLRHR 1139
CGK F + + HR
Sbjct: 759 ICGKSFSWRSNLTVHHR 775
>gi|74027274 zinc finger protein 226 isoform a [Homo sapiens]
Length = 803
Score = 40.0 bits (92), Expect = 0.013
Identities = 17/54 (31%), Positives = 31/54 (57%)
Query: 1075 HAPLTPLERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPYHCEACGKDF 1128
++P+ P+ + H + + G ++ A L+T QK V+++PY C+ CGK F
Sbjct: 291 YSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGF 344
Score = 33.5 bits (75), Expect = 1.2
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 15/94 (15%)
Query: 1049 YNCLTNDTDLYSDCLRTFWTCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGAEEAALET 1108
YNC +C R F H H L E+ + C G + + L++
Sbjct: 363 YNC--------EECGRAFSQASHLQDHQRLHTGEKPFKCDAC------GKSFSRNSHLQS 408
Query: 1109 LQKTSVLQRPYHCEACGKDFLFTPTEVLRHRKQH 1142
Q+ ++PY CE CGK F+ + + + H++ H
Sbjct: 409 HQRVHTGEKPYKCEECGKGFICS-SNLYIHQRVH 441
Score = 33.5 bits (75), Expect = 1.2
Identities = 20/77 (25%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 1067 WTCPHCGLH---APLTPLERIAHENTCP-QAPQDGPPGAEEAALETLQKTSVLQRPYHCE 1122
+ C CG + A L + H P + G + + L++ Q+ ++PY CE
Sbjct: 699 YKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCE 758
Query: 1123 ACGKDFLFTPTEVLRHR 1139
CGK F + + HR
Sbjct: 759 ICGKSFSWRSNLTVHHR 775
>gi|115495000 zinc finger protein 17 [Homo sapiens]
Length = 662
Score = 40.0 bits (92), Expect = 0.013
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
Query: 1053 TNDTDLYSDCLRTFWTCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGAEEAALETLQKT 1112
T D+DL L + W PH H + + + +C Q +D + L QK
Sbjct: 157 TGDSDLQQQALHSGWK-PHRDTHG-VEAFQSGQNNYSCTQCGKDF---CHQHTLFEHQKI 211
Query: 1113 SVLQRPYHCEACGKDFLFTPTEVLRHRKQH 1142
+RPY C CGK F + +++++H++ H
Sbjct: 212 HTEERPYECSECGKLFRYN-SDLIKHQRNH 240
Score = 34.3 bits (77), Expect = 0.70
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 1104 AALETLQKTSVLQRPYHCEACGKDFLFTPTEVLRHRKQH 1142
+ L+T Q+ +RPY C CGK F + RHR+ H
Sbjct: 511 STLDTHQRIHTGERPYECSECGKFFRHNSNHI-RHRRNH 548
Score = 32.7 bits (73), Expect = 2.0
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 6/80 (7%)
Query: 1060 SDCLRTFWTCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPY 1119
S+C + F T H H + ER N C G +AL QK +RP+
Sbjct: 305 SECGKAFLTQAHLVGHQKIHTGERPYGCNEC------GKYFMYSSALIRHQKVHTGERPF 358
Query: 1120 HCEACGKDFLFTPTEVLRHR 1139
+C CGK F+ + T ++ R
Sbjct: 359 YCCECGKFFMDSCTLIIHQR 378
Score = 32.0 bits (71), Expect = 3.5
Identities = 13/33 (39%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
Query: 1110 QKTSVLQRPYHCEACGKDFLFTPTEVLRHRKQH 1142
Q+ ++PY C CGK F + T ++RH+K H
Sbjct: 377 QRVHTGEKPYECNECGKFFRYRST-LIRHQKVH 408
Score = 31.6 bits (70), Expect = 4.5
Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
Query: 1110 QKTSVLQRPYHCEACGKDFLFTPTEVLRHRKQH 1142
QK +RPY C CGK FL + +L+H++ H
Sbjct: 265 QKIHTGERPYECSECGKAFL-RKSHLLQHQRIH 296
Score = 31.6 bits (70), Expect = 4.5
Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 7/83 (8%)
Query: 1060 SDCLRTFWTCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPY 1119
++C R F H H + ER + C + D + L + ++ ++PY
Sbjct: 557 TECGRVFSQNSHLIRHQKVHTRERTYKCSKCGKFFMDS------STLISHERVHTGEKPY 610
Query: 1120 HCEACGKDFLFTPTEVLRHRKQH 1142
C CGK F + + +++HR+ H
Sbjct: 611 ECSECGKVFRYN-SSLIKHRRIH 632
Score = 31.2 bits (69), Expect = 5.9
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 1110 QKTSVLQRPYHCEACGKDFLFTPTEVLRHR 1139
QK ++PY C CGK F+ T T ++ R
Sbjct: 405 QKVHTGEKPYECSECGKFFMDTSTLIIHQR 434
>gi|24432013 zinc finger protein 668 [Homo sapiens]
Length = 619
Score = 40.0 bits (92), Expect = 0.013
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 15/85 (17%)
Query: 1067 WTCPHCGLHAPLTPLERI-AHENT--------CPQAPQDGPPGAEEAALETLQKTSVLQR 1117
+ CP CG T L +HE T CP+ G ++ ++ Q+ +
Sbjct: 252 YRCPACG--KGFTQLSSYQSHERTHSGEKPFLCPRC---GRMFSDPSSFRRHQRAHEEVK 306
Query: 1118 PYHCEACGKDFLFTPTEVLRHRKQH 1142
PYHCE CGKDF P ++ HR+ H
Sbjct: 307 PYHCEKCGKDFR-QPADLAMHRRVH 330
Score = 38.1 bits (87), Expect = 0.048
Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 17/98 (17%)
Query: 1049 YNCLTNDTDLYSDCLRTFWTCP----HCGLHAPLTPLERIAHENTCPQAPQDGPPGAEEA 1104
Y CL+ C +TF P H H P E +A P+ AEEA
Sbjct: 22 YKCLS--------CTKTFPNAPRAARHAATHGPADCSEEVAEVKPKPETEAK----AEEA 69
Query: 1105 ALETLQKTSVLQRPYHCEACGKDFLFTPTEVLRHRKQH 1142
+ E + ++ RPY C C K + P E+ H + H
Sbjct: 70 SGEKVSGSAAKPRPYACPLCPKAYKTAP-ELRSHGRSH 106
Score = 35.4 bits (80), Expect = 0.31
Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
Query: 1101 AEEAALETLQKTSVLQRPYHCEACGKDFLFTPTEVLRHRKQH 1142
AE A+L + +RP+HC ACGK F+ + + + +H + H
Sbjct: 374 AERASLTKHSRVHSGERPFHCNACGKSFVVS-SSLRKHERTH 414
Score = 32.3 bits (72), Expect = 2.6
Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 16/81 (19%)
Query: 1062 CLRTFWTCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPYHC 1121
CLR H HA P R AH CP+A + L+ Q+ +RPY C
Sbjct: 126 CLRV-----HLASHAGELPF-RCAH---CPKAY------GALSKLKIHQRGHTGERPYAC 170
Query: 1122 EACGKDFLFTPTEVLRHRKQH 1142
CGK F P+ +HR+ H
Sbjct: 171 ADCGKSFA-DPSVFRKHRRTH 190
Score = 32.3 bits (72), Expect = 2.6
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 4/66 (6%)
Query: 1067 WTCPHCG-LHAPLTPLERIAHENTCPQ---APQDGPPGAEEAALETLQKTSVLQRPYHCE 1122
++C CG +A L L +T + + G + ++L Q+ Q+PY C
Sbjct: 196 YSCERCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCP 255
Query: 1123 ACGKDF 1128
ACGK F
Sbjct: 256 ACGKGF 261
>gi|55741659 zinc finger protein 14-like [Homo sapiens]
Length = 533
Score = 39.7 bits (91), Expect = 0.017
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 6/68 (8%)
Query: 1061 DCLRTFWTCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGAEEAALETLQKTSVLQRPYH 1120
DC +TF C H H L E++ C +A GP L QK ++PY
Sbjct: 288 DCGKTFRQCTHLTRHQRLHTAEKLYECKECGKAFVCGPD------LRVHQKIHFGEKPYE 341
Query: 1121 CEACGKDF 1128
C+ CGK F
Sbjct: 342 CKECGKAF 349
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,500,030
Number of Sequences: 37866
Number of extensions: 2217882
Number of successful extensions: 16002
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 419
Number of HSP's that attempted gapping in prelim test: 11698
Number of HSP's gapped (non-prelim): 4599
length of query: 1143
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1030
effective length of database: 13,968,660
effective search space: 14387719800
effective search space used: 14387719800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.