Guide to the Human Genome
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Name: VHL Sequence: fasta or formatted (172aa) NCBI GI: 38045906
Description:

von Hippel-Lindau tumor suppressor isoform 2

Referenced in:

Adrenals
Cullins and SCF Complexes
Oxygen Sensing and Hemoglobin
PHD Finger Proteins
RNA Polymerase and General Transcription Factors

Other entries for this name:
alt prot [213aa] von Hippel-Lindau tumor suppressor isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.7          8           1
 C cysteine            1.2          2           1
 D aspartate           4.7          8           1
 E glutamate          16.9         29           3
 F phenylalanine       1.2          2           1
 G glycine             8.1         14           2
 H histidine           1.7          3           1
 I isoleucine          2.3          4           1
 K lysine              1.7          3           1
 L leucine             7.6         13           1
 M methionine          1.7          3           1
 N asparagine          3.5          6           1
 P proline             9.3         16           2
 Q glutamine           3.5          6           1
 R arginine           11.0         19           2
 S serine              5.8         10           1
 T threonine           2.3          4           1
 V valine              8.1         14           2
 W tryptophan          1.2          2           1
 Y tyrosine            3.5          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   von Hippel-Lindau tumor suppressor isoform 2 
VHL                   0.940   von Hippel-Lindau tumor suppressor isoform 1 
VHLL                  0.236   von Hippel-Lindau tumor suppressor-like 
SLC24A1               0.048   solute carrier family 24 (sodium/potassium/calcium ex...
TGOLN2                0.048   trans-golgi network protein 2 
PTMS                  0.045   parathymosin 
LOC100132713          0.042   PREDICTED: similar to hCG1654128 
LOC100132713          0.042   PREDICTED: similar to hCG1654128 
ZFHX2                 0.042   PREDICTED: zinc finger homeobox 2 
ZFHX2                 0.042   PREDICTED: zinc finger homeobox 2 
ZFHX2                 0.042   PREDICTED: zinc finger homeobox 2 
LOC100132713          0.039   PREDICTED: similar to hCG1654128 
RANGAP1               0.030   Ran GTPase activating protein 1 
YTHDC1                0.030   splicing factor YT521-B isoform 2 
YTHDC1                0.030   splicing factor YT521-B isoform 1 
PALM3                 0.030   hypothetical protein LOC342979 
NEFH                  0.030   neurofilament, heavy polypeptide 200kDa 
NEFM                  0.030   neurofilament, medium polypeptide 150kDa isoform 1 ...
NEFM                  0.030   neurofilament, medium polypeptide 150kDa isoform 2 ...
NEFL                  0.030   neurofilament, light polypeptide 68kDa 
AATF                  0.030   apoptosis antagonizing transcription factor 
BDP1                  0.030   transcription factor-like nuclear regulator 
ZNF592                0.030   zinc finger protein 592 
TNNT2                 0.027   troponin T type 2, cardiac isoform 3 
TNNT2                 0.027   troponin T type 2, cardiac isoform 2 
LOC100287390          0.027   PREDICTED: hypothetical protein XP_002342820 
LOC100287390          0.027   PREDICTED: hypothetical protein 
MYT1                  0.027   myelin transcription factor 1 
RPGR                  0.027   retinitis pigmentosa GTPase regulator isoform C [Hom...
KIF21B                0.027   kinesin family member 21B 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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