Guide to the Human Genome
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Name: VHL Sequence: fasta or formatted (213aa) NCBI GI: 4507891
Description:

von Hippel-Lindau tumor suppressor isoform 1

Referenced in:

Adrenals
Cullins and SCF Complexes
Oxygen Sensing and Hemoglobin
PHD Finger Proteins
RNA Polymerase and General Transcription Factors

Other entries for this name:
alt prot [172aa] von Hippel-Lindau tumor suppressor isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.7         10           1
 C cysteine            0.9          2           1
 D aspartate           5.2         11           1
 E glutamate          14.1         30           3
 F phenylalanine       2.3          5           1
 G glycine             8.5         18           2
 H histidine           2.3          5           1
 I isoleucine          2.8          6           1
 K lysine              1.4          3           1
 L leucine             9.4         20           2
 M methionine          1.4          3           1
 N asparagine          4.2          9           1
 P proline             8.9         19           2
 Q glutamine           3.8          8           1
 R arginine            9.4         20           2
 S serine              5.2         11           1
 T threonine           3.3          7           1
 V valine              8.0         17           2
 W tryptophan          1.4          3           1
 Y tyrosine            2.8          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   von Hippel-Lindau tumor suppressor isoform 1 
VHL                   0.748   von Hippel-Lindau tumor suppressor isoform 2 
VHLL                  0.349   von Hippel-Lindau tumor suppressor-like 
SLC24A1               0.038   solute carrier family 24 (sodium/potassium/calcium ex...
TGOLN2                0.038   trans-golgi network protein 2 
PTMS                  0.036   parathymosin 
LOC100132713          0.034   PREDICTED: similar to hCG1654128 
LOC100132713          0.034   PREDICTED: similar to hCG1654128 
ZFHX2                 0.034   PREDICTED: zinc finger homeobox 2 
ZFHX2                 0.034   PREDICTED: zinc finger homeobox 2 
ZFHX2                 0.034   PREDICTED: zinc finger homeobox 2 
LOC100132713          0.031   PREDICTED: similar to hCG1654128 
RANGAP1               0.024   Ran GTPase activating protein 1 
YTHDC1                0.024   splicing factor YT521-B isoform 2 
YTHDC1                0.024   splicing factor YT521-B isoform 1 
PALM3                 0.024   hypothetical protein LOC342979 
NEFH                  0.024   neurofilament, heavy polypeptide 200kDa 
NEFM                  0.024   neurofilament, medium polypeptide 150kDa isoform 1 ...
NEFM                  0.024   neurofilament, medium polypeptide 150kDa isoform 2 ...
NEFL                  0.024   neurofilament, light polypeptide 68kDa 
AATF                  0.024   apoptosis antagonizing transcription factor 
BDP1                  0.024   transcription factor-like nuclear regulator 
ZNF592                0.024   zinc finger protein 592 
TNNT2                 0.022   troponin T type 2, cardiac isoform 3 
TNNT2                 0.022   troponin T type 2, cardiac isoform 2 
LOC100287390          0.022   PREDICTED: hypothetical protein XP_002342820 
LOC100287390          0.022   PREDICTED: hypothetical protein 
MYT1                  0.022   myelin transcription factor 1 
RPGR                  0.022   retinitis pigmentosa GTPase regulator isoform C [Hom...
KIF21B                0.022   kinesin family member 21B 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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