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Search of human proteins with 38016935
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38016935 MLF1 interacting protein [Homo sapiens]
(418 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38016935 MLF1 interacting protein [Homo sapiens] 819 0.0
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 47 2e-05
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 47 4e-05
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ... 45 1e-04
gi|38569484 kinesin family member 21A [Homo sapiens] 44 3e-04
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 44 4e-04
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 43 5e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 43 6e-04
gi|219842247 periphilin 1 isoform 7 [Homo sapiens] 42 0.001
gi|62244004 modulator of estrogen induced transcription isoform ... 42 0.001
gi|63176611 modulator of estrogen induced transcription isoform ... 42 0.001
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 41 0.002
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 41 0.002
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 41 0.002
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 41 0.002
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 41 0.002
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 41 0.002
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 41 0.002
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 41 0.002
gi|110347568 centrosomal protein 152kDa [Homo sapiens] 41 0.002
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 41 0.002
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 41 0.002
gi|21735548 centrosomal protein 2 [Homo sapiens] 41 0.002
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 41 0.002
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] 41 0.002
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens] 41 0.002
gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens] 41 0.002
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 40 0.003
gi|55770834 centromere protein F [Homo sapiens] 40 0.003
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 40 0.003
>gi|38016935 MLF1 interacting protein [Homo sapiens]
Length = 418
Score = 819 bits (2115), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MAPRGRRRPRPHRSEGARRSKNTLERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGE 60
MAPRGRRRPRPHRSEGARRSKNTLERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGE
Sbjct: 1 MAPRGRRRPRPHRSEGARRSKNTLERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGE 60
Query: 61 NEKDEETYETFDPPLHSTAIYADEEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASEIES 120
NEKDEETYETFDPPLHSTAIYADEEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASEIES
Sbjct: 61 NEKDEETYETFDPPLHSTAIYADEEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASEIES 120
Query: 121 VKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAES 180
VKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAES
Sbjct: 121 VKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAES 180
Query: 181 VTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCP 240
VTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCP
Sbjct: 181 VTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCP 240
Query: 241 EGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLT 300
EGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLT
Sbjct: 241 EGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLT 300
Query: 301 NLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLRNAAYFLSN 360
NLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLRNAAYFLSN
Sbjct: 301 NLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLRNAAYFLSN 360
Query: 361 LKQLYQDYSDVQAQEPNVKETYDSSSLPALLFKARTLLGAESHLRNINHQLEKLLDQG 418
LKQLYQDYSDVQAQEPNVKETYDSSSLPALLFKARTLLGAESHLRNINHQLEKLLDQG
Sbjct: 361 LKQLYQDYSDVQAQEPNVKETYDSSSLPALLFKARTLLGAESHLRNINHQLEKLLDQG 418
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 47.4 bits (111), Expect = 2e-05
Identities = 82/352 (23%), Positives = 142/352 (40%), Gaps = 43/352 (12%)
Query: 22 NTLERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGENEKDEETYETFDPPLHSTAIY 81
N E T K K GQK K FD D+ ++ +KD ++ +T P + +
Sbjct: 87 NEEEFTSKDKKKKGQKGKK-QSFDDNDSEELE--------DKDSKSKKTAKPKVEMYSGS 137
Query: 82 ADEEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSES 141
D+++F+K L GK K + G+E E S KI + D+S+
Sbjct: 138 DDDDDFNK-----LPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDE 192
Query: 142 IEES----DTRRKVKSAEKISTQRHE-----VIRTTASSELSEKPAESVTSKKTGPLSAQ 192
+S +K K I + + I+T A + +K E KK A+
Sbjct: 193 FLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERE---RKKRDEEKAK 249
Query: 193 PSVEKENLAIESQSKTQKKGKISHDKRKKSRSKA-IGSDTSDIVHIWCPEGMKT----SD 247
KE +E+ K Q K K S K ++ K+ + DT I E +T D
Sbjct: 250 LRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPA--SEEKAETPTAAED 307
Query: 248 IKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNA 307
E + + +K E +++ + K + AT ++E K+ +E + + +
Sbjct: 308 DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKA-MQEALAKLKEEEERQKREEEERI 366
Query: 308 KMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLRNAAYFLS 359
K + ++E KR+ ++E L E + ++ Q + KERK L+ L+
Sbjct: 367 KRLEELEAKRK-----EEERLEQEKRERKKQKE----KERKERLKKEGKLLT 409
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 46.6 bits (109), Expect = 4e-05
Identities = 64/327 (19%), Positives = 140/327 (42%), Gaps = 27/327 (8%)
Query: 103 EAKRSSDTSGNEAS----EIESVKISAKKPGRKLRPISDDSESIE------ESDTRRKVK 152
+AK+ D+S E E+ES++ + +R + +ES + E + +
Sbjct: 976 KAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDV 1035
Query: 153 SAEKISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKG 212
E+ + H + T S E++ S L+ +++ +E Q ++
Sbjct: 1036 EKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRA 1095
Query: 213 KISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESK 272
K DK ++ + ++++EL + L + +K + Q +E
Sbjct: 1096 KAMVDKELEAEKLQKEQKIKE-------HATTVNELEELQVQLQKEKKQLQKTMQELEL- 1147
Query: 273 VCKAAIATFYVNVK-EQFIKMLKE-SQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRL 330
V K A T +N++ + +++KE +Q LTN K + +I+ ++Q+ +Q+E+ L
Sbjct: 1148 VKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSL 1207
Query: 331 EPQLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPAL 390
+ ++Q + K ++K+ + L++ KQ D+ +QA ++K ++S
Sbjct: 1208 QSSVQQYEEKNTKIKQLLVKTKKE---LADSKQAETDHLILQA---SLKGELEASQQQVE 1261
Query: 391 LFKARTLLGAESHLRNINHQLEKLLDQ 417
++K + L S I+ L+ +Q
Sbjct: 1262 VYKIQ-LAEITSEKHKIHEHLKTSAEQ 1287
Score = 30.0 bits (66), Expect = 4.1
Identities = 52/297 (17%), Positives = 131/297 (44%), Gaps = 38/297 (12%)
Query: 79 AIYADEEEFSKHC-GLSLSSTPPGKEAKRSSDTSGNEASEIESVKISAKKPGRKLRP--- 134
A+ ++ E + C L + +E + S G+ E+E I+ K L+
Sbjct: 80 ALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELM 139
Query: 135 ISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQPS 194
S ++++ +++++ A + E ++ +SE + K + K +P
Sbjct: 140 AVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEK------IRPG 193
Query: 195 VEKENLAIESQ---SKTQKKGKISH-----DKRKKSRSKAIGSDTSDIVHIWCPEGMKTS 246
E++ L ++ Q + +KK ++ + + K I S +++ + + +
Sbjct: 194 FEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQL---KAIHQE 250
Query: 247 DIKELNIVLPEFEKTHLEHQQRIES---------KVCKAAIATFYVNVKEQFIKMLKESQ 297
++KEL + + E + EH+ I K C+A+ N+++++ L+ +
Sbjct: 251 EVKEL---MCQIEASAKEHEAEINKLNELKENLVKQCEASEK----NIQKKYECELENLR 303
Query: 298 MLTNLKRKNAKMISDIEKKRQRMIEVQDELLR-LEPQLKQLQTKYDELKERKSSLRN 353
T+ ++ ++ S + ++ + +V +E ++ LE LK+L++++ LK+ + + N
Sbjct: 304 KATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNN 360
Score = 29.6 bits (65), Expect = 5.3
Identities = 58/278 (20%), Positives = 108/278 (38%), Gaps = 38/278 (13%)
Query: 109 DTSGNEASEIESVK----ISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEV 164
+++G + E ES+K + +KLR + +++ E+ R + ++ + +S Q
Sbjct: 496 ESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVP 555
Query: 165 IRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRS 224
L EK + S + K N E + K K SH++
Sbjct: 556 ELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHK 615
Query: 225 KA---------IGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCK 275
K +G + K + EL L E K ++ Q++E + +
Sbjct: 616 KCEREERLILELGKKVEQTIQYNSELEQK---VNELTGGLEETLKEKDQNDQKLEKLMVQ 672
Query: 276 AAIATFYVNVKEQFIKML-KESQMLTNLKRKNAK----------------MISDIEKKRQ 318
+ + V +K L +E+ L++ K++ ++ I+ +EKK Q
Sbjct: 673 MKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQ 732
Query: 319 RMIEVQDELLRL--EPQLKQLQTK---YDELKERKSSL 351
M+E QD L +L Q+++L K Y LKE S +
Sbjct: 733 LMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEV 770
>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2
[Homo sapiens]
Length = 1235
Score = 45.1 bits (105), Expect = 1e-04
Identities = 49/216 (22%), Positives = 93/216 (43%), Gaps = 15/216 (6%)
Query: 139 SESIEESDTRRKVKSAEKISTQRHEVIRTTASS-ELSEKPAESVTSKKTGPL-SAQPSVE 196
S+ I+E K E Q +I+ T + + S+ E + K Q ++
Sbjct: 679 SQKIQELKGLMKTLRKETDLKQIQTLIQGTQTRLKYSQNELEMIKKKHLVAFYQEQSQLQ 738
Query: 197 KENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLP 256
E L IESQ +G +R K + I DI +C E + +I+E
Sbjct: 739 SELLNIESQCIMLSEGIKERQRRIKEFQEKIDKVEDDIFQHFCEE-IGVENIRE------ 791
Query: 257 EFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIK--MLKESQMLTNLK---RKNAKMIS 311
FE H++ QQ I+ K + +NV+ ++ + + K+ + LK +K ++ I
Sbjct: 792 -FENKHVKRQQEIDQKRLEFEKQKTRLNVQLEYSRSHLKKKLNKINTLKETIQKGSEDID 850
Query: 312 DIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKER 347
++K + ++ +EL+ + QLK ++ + E+
Sbjct: 851 HLKKAEENCLQTVNELMAKQQQLKDIRVTQNSSAEK 886
Score = 32.0 bits (71), Expect = 1.1
Identities = 52/263 (19%), Positives = 117/263 (44%), Gaps = 44/263 (16%)
Query: 117 EIESVK--ISAKKPGRKLRPISDDSESIEESDTRRK-VKSAEKISTQRHEVIRTTASSEL 173
E++SV+ ++ K+P + ++ + S +++ D +K +K +EK +++ + I+ +EL
Sbjct: 283 ELKSVETLLNQKRP-QYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKAL-ETEL 340
Query: 174 SEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSD 233
++ A + +K +E+E L + + + + + K+ K + + T
Sbjct: 341 ADLDAAWRSFEK--------QIEEEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQ 392
Query: 234 IVHIWCPEGMKTSDIK---------ELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVN 284
+ + + KT + + E+ L + ++ +H++RIE
Sbjct: 393 LEKLQWEQ--KTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKL------------ 438
Query: 285 VKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDEL 344
E++ K + L K++ ++ +IEK + RM E +EL + +L+ E
Sbjct: 439 --EEYTKTCMDC--LKEKKQQEETLVDEIEKTKSRMSEFNEELNLIRSELQNAGIDTHEG 494
Query: 345 KERKSSLRNAAYFLSNLKQLYQD 367
K + + A L +LK+LY D
Sbjct: 495 KRQ----QKRAEVLEHLKRLYPD 513
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 43.9 bits (102), Expect = 3e-04
Identities = 64/297 (21%), Positives = 121/297 (40%), Gaps = 42/297 (14%)
Query: 135 ISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSE------LSEKPAESVTSKKTGP 188
+S D E+IE D +K EK+ + ++ A E +K + V+ ++
Sbjct: 528 LSSDKETIEIIDLAKK--DLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNE 585
Query: 189 LSAQPSVEKENLAIESQSKTQKK-----GKISHDKRKKSRSKAIGSDTSDIVHIWCPEGM 243
L + S E + E + + +++ G+ S + +S KA + +D+ +I C +
Sbjct: 586 LEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKA--NYQADLANITCEIAI 643
Query: 244 KTSDIKELNIV---LPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLT 300
K I EL L +K + E ++ K+ + ++Q ++ L + +
Sbjct: 644 KQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLE------RDQVLQNLGSVESYS 697
Query: 301 NLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLRNAAYFLSN 360
K K K+ S+ EKK Q M K+LQ KE L+N + +
Sbjct: 698 EEKAK--KVRSEYEKKLQAMN-------------KELQRLQAAQKEHARLLKNQSQYEKQ 742
Query: 361 LKQLYQDYSDVQAQEPNVKETYDSSSLPALLFKA---RTLLGAESHLRNINHQLEKL 414
LK+L QD +++ + + + A L ++ R + + R +HQL L
Sbjct: 743 LKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLL 799
Score = 30.4 bits (67), Expect = 3.1
Identities = 59/329 (17%), Positives = 129/329 (39%), Gaps = 36/329 (10%)
Query: 31 KDKAGQKCKPIDVFDFPDNSDVSSIGRLGENEKDEETYETFDPPLHSTAIYADEEEFSKH 90
K K +K K V DN+D + + + E E + + DEEE +
Sbjct: 547 KLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEE 606
Query: 91 CGLSLSSTPPGKEAKRSSDTSGNEASEIESV--KISAKKPGRKLRPISDDSESIEESDTR 148
+ E+ SD N +++ ++ +I+ K + + D+ E+ ++
Sbjct: 607 EEDDIDGGESSDESDSESDEKANYQADLANITCEIAIK------QKLIDELENSQKRLQT 660
Query: 149 RKVKSAEKISTQRHEVIRTTASSELSEKPAESVTS-KKTGPLSAQPSVEKENLAIESQSK 207
K + EK+ +H++ T + + SV S + + EK+ A+ + +
Sbjct: 661 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 720
Query: 208 TQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQ 267
+ + H + K++S+ +K+L + E +KT + +
Sbjct: 721 RLQAAQKEHARLLKNQSQ------------------YEKQLKKLQQDVMEMKKTKVRLMK 762
Query: 268 RIESKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMI--EVQD 325
+++ + KA + + + + I LK+ Q KR + + + +K+ Q ++ +
Sbjct: 763 QMKEEQEKARLTE---SRRNREIAQLKKDQR----KRDHQLRLLEAQKRNQEVVLRRKTE 815
Query: 326 ELLRLEPQLKQLQTKYDELKERKSSLRNA 354
E+ L Q++ + K RK S +A
Sbjct: 816 EVTALRRQVRPMSDKVAGKVTRKLSSSDA 844
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 43.5 bits (101), Expect = 4e-04
Identities = 73/367 (19%), Positives = 141/367 (38%), Gaps = 76/367 (20%)
Query: 60 ENEKDEETYETFDPPLHSTAIYADEEEFSKHCG------LSLSSTPPGKEAKRSSDTSGN 113
EN++D E + I + E C + S T KE + S
Sbjct: 326 ENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVE 385
Query: 114 EASEIESVKISAKKPGRKLRPISDDSESIEES----------DTRRKVKSAEKISTQ--- 160
E ++ A+ +L ++ D+ E++ + + + S EK Q
Sbjct: 386 EVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSL 445
Query: 161 -----RHEVIRTTASSELS---------------EKPAESVTSKKTGPLSAQPSVEKEN- 199
+EVI++TA+ ++S E+ S+K ++ ++++N
Sbjct: 446 LKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQ 505
Query: 200 -------LAIESQSKTQKKG-----KISHDKR-KKSRSKAIGSDTSDIVHIWCPEGMKTS 246
L + SK Q +G K+ D +K R + D DI K
Sbjct: 506 EATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDIT--------KEL 557
Query: 247 DIKELNIVLPEFEKTHLE-HQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLT-NLKR 304
D+++ ++ E L +Q++E KV E + L +SQ ++++
Sbjct: 558 DVQKEKLIQSEVALNDLHLTKQKLEDKV-------------ENLVDQLNKSQESNVSIQK 604
Query: 305 KNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLRNAAYFLSNLKQL 364
+N ++ I + + + +++EL++ Q K LKER++ +RN LS L+QL
Sbjct: 605 ENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQL 664
Query: 365 YQDYSDV 371
++ V
Sbjct: 665 NENLKKV 671
Score = 38.5 bits (88), Expect = 0.011
Identities = 46/238 (19%), Positives = 97/238 (40%), Gaps = 8/238 (3%)
Query: 146 DTRRKVKSAEKISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQ 205
+ + V + E + Q E + L + + G + A+ K+ L E+
Sbjct: 678 ENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEAN 737
Query: 206 SKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEH 265
+ ++S+ + + + + + H+ K +I EL + + + H E
Sbjct: 738 KYEKTIEELSNARNLNTSALQLEHE-----HLIKLNQKKDMEIAELKKNIEQMDTDHKET 792
Query: 266 QQRIESKVCKAAIATFYVNVKEQFIKMLKE-SQMLTNLKRKNAKMISDIEKKRQRMIEVQ 324
+ + S + + T +N KE FI+ LKE S L K ++ + E RQ + E
Sbjct: 793 KDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKD 852
Query: 325 DELLRLEPQLKQLQTKYDELKERKSSLRNAA--YFLSNLKQLYQDYSDVQAQEPNVKE 380
L ++ + LQ + + L+E +S A L ++ +L + S + + +++E
Sbjct: 853 RSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEE 910
Score = 34.3 bits (77), Expect = 0.22
Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 10/179 (5%)
Query: 246 SDIKELNIVLPEFEKTHL------EHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQML 299
S+ + LN + E HL + + E K + T + K+ L+E + L
Sbjct: 747 SNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQL 806
Query: 300 TNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLRNAAYFLS 359
T L K I EK ++R ++Q+EL + L++ + ++E+ SL + +
Sbjct: 807 TQLINKKEIFI---EKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENN 863
Query: 360 NLKQLYQDYSDVQAQEPNVKETYDSSSLPALLFKARTLLGAESHL-RNINHQLEKLLDQ 417
+L++ + + Q++ V + S+ L + L + HL I H + + DQ
Sbjct: 864 HLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQ 922
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 43.1 bits (100), Expect = 5e-04
Identities = 85/479 (17%), Positives = 179/479 (37%), Gaps = 88/479 (18%)
Query: 10 RPHRSEGARRSKNTLERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGENEKDEET-- 67
+ H+++ KN+L+ H ++ + ++ K I L +++ ++
Sbjct: 571 KSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKL 630
Query: 68 YETFDPPLHSTAIYAD------EEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASEIESV 121
E + +AI AD EEE +K L S + R +T A+ I +
Sbjct: 631 LEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEET----ATIITQL 686
Query: 122 KISAKKPGRKLRPISDDSESIE---ESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPA 178
K+ R+L+ ++ +S++ E + + +K +K ++ IRT + L EK
Sbjct: 687 KLERDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTLKAESLEEKNM 746
Query: 179 ESVTSKKTGPLSAQP-----------------------------------SVEKENLAIE 203
+ + L +Q S+E+E+L
Sbjct: 747 AKIHRGQLEKLKSQCDRLTEELTQNENENKKLKLKYQCLKDQLEEREKHISIEEEHLRRM 806
Query: 204 SQSKTQKKGKI-------------------------SHDKRKKSRSKAIGSDTSDIVHIW 238
+++ Q K ++ S D +K + + G D H W
Sbjct: 807 EEARLQLKDQLLCLETEQESILGVIGKEIDAACKTFSKDSVEKLKVFSSGPDIHYDPHRW 866
Query: 239 CPEGMKTSDIKELNIVLPEF-EKTHLEHQQRIESKVCKAAIATFYVNVKEQ----FIKML 293
E KT +L + E E+ + E R + +C+ + N + + F ++
Sbjct: 867 LAES-KT----KLQWLCEELKERENREKNLRHQLMLCRQQLRNLTENKESELQCLFQQIE 921
Query: 294 KESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLRN 353
++ Q+L + R+ ++ + ++K + M +QD ++ LE + + + E+ S L +
Sbjct: 922 RQEQLLDEIHREKRDLLEETQRKDEEMGSLQDRVIALETSTQVALDHLESVPEKLSLLED 981
Query: 354 AAYF---LSNLKQLYQDYSDVQAQEPNVKETYDSSSLPALLFKARTLLGAESHLRNINH 409
F S+ ++ YS + + +++ D + FK SH R ++H
Sbjct: 982 FKDFRDSCSSSERTDGRYSKYRVRRNSLQHHQDDTKYRTKSFKGDRTFLEGSHTRGLDH 1040
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 42.7 bits (99), Expect = 6e-04
Identities = 62/277 (22%), Positives = 113/277 (40%), Gaps = 41/277 (14%)
Query: 96 SSTPPGKEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESI------------- 142
+ +P +EAK ++ E ++ VK AK P P+ ++++S
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAK-SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPT 642
Query: 143 -EESDTRRKVKSAEKISTQRHEVIRTTASSELS--EKPAESVTSKKTGPLSAQPSV---- 195
EE+ + K KS EK + E ++ +E EK V ++ P A+ V
Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA 702
Query: 196 ---EKENLAIESQSKTQKKGKISHDKRKKSRSKA---IGSDTSDIVHIWCPEGMKTSDIK 249
EK ++ ++K+ +K K + K+ KA + + PE KT D+K
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK 762
Query: 250 ELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKM 309
PE + E + K + A + VKE+ +K + + +++AK
Sbjct: 763 S-----PEAKTPAKEEARSPADKFPEKAKSP----VKEE----VKSPEKAKSPLKEDAKA 809
Query: 310 -ISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELK 345
+I KK + V++E E ++K+ K +E K
Sbjct: 810 PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEK 846
Score = 40.8 bits (94), Expect = 0.002
Identities = 47/222 (21%), Positives = 84/222 (37%), Gaps = 12/222 (5%)
Query: 2 APRGRRRPRPHRSEGARRSKNTLERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGEN 61
+P + P ++ ++K+ ++ +KA K S V + E
Sbjct: 690 SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK 749
Query: 62 EKDEETYETFDPPLHSTAIYADEEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASEIESV 121
K E +T D A EE S + P KE +S + + + E
Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE---- 805
Query: 122 KISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAESV 181
AK P +++ + ++E + ++VK E E T +E + +
Sbjct: 806 --DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEE 863
Query: 182 TSKKTGPLSAQPSV-EKENLAIE--SQSKTQKKGKISHDKRK 220
KK P +P V EK+ A+E +SK + K + + DK+K
Sbjct: 864 APKKEAP---KPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902
Score = 37.0 bits (84), Expect = 0.033
Identities = 44/181 (24%), Positives = 72/181 (39%), Gaps = 33/181 (18%)
Query: 60 ENEKDEETYETFDPPLHSTAIYADEEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASEIE 119
E E + ET PP A + E+E + +P +EAK ++ E E
Sbjct: 491 EEEAEGGEEETKSPPAEEAA--SPEKE---------AKSPVKEEAKSPAEAKSPEKEE-- 537
Query: 120 SVKISAKKPG------RKLRPISDDSES--------IEESDTRRKVKSAEKISTQRHEVI 165
AK P + P ++++S EE+ + +VKS EK + E
Sbjct: 538 -----AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 592
Query: 166 RTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSK 225
++ A ++ EK V + P A+ V KE ++ K+ +K K + KS K
Sbjct: 593 KSPAEAKSPEKAKSPVKEEAKSPAEAKSPV-KEEAKSPAEVKSPEKAKSPTKEEAKSPEK 651
Query: 226 A 226
A
Sbjct: 652 A 652
Score = 33.5 bits (75), Expect = 0.37
Identities = 31/131 (23%), Positives = 54/131 (41%), Gaps = 8/131 (6%)
Query: 96 SSTPPGKEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAE 155
+ +P +EAK + E E AK P P S + EE+ + + KS E
Sbjct: 550 AKSPAKEEAKSPPEAKSPEKEE-------AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE 602
Query: 156 KISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKIS 215
K + E ++ A ++ K ++ P A+ S KE ++K+ +K +
Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK-SPTKEEAKSPEKAKSPEKEEAK 661
Query: 216 HDKRKKSRSKA 226
++ KS KA
Sbjct: 662 SPEKAKSPVKA 672
Score = 32.3 bits (72), Expect = 0.82
Identities = 39/188 (20%), Positives = 74/188 (39%), Gaps = 22/188 (11%)
Query: 9 PRPHRSEGARRSKNTLERTHSMKDKAGQKCKPID--------VFDFPDNSDVSSIGRLGE 60
P+ E A + T E+ S K++A +K P + P S V + E
Sbjct: 839 PKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE 898
Query: 61 NEKDEETYETFDPP---LHSTAIYADEEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASE 117
++K T E P + A ++ E +K + P K A++ + ++
Sbjct: 899 DKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTK 958
Query: 118 IESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKP 177
E K +KP + + DD +++ + ++ K + AEK ++++ + KP
Sbjct: 959 EEKAKKPEEKPKTEAKAKEDD-KTLSKEPSKPKAEKAEK----------SSSTDQKDSKP 1007
Query: 178 AESVTSKK 185
E T K
Sbjct: 1008 PEKATEDK 1015
>gi|219842247 periphilin 1 isoform 7 [Homo sapiens]
Length = 348
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/278 (20%), Positives = 102/278 (36%), Gaps = 46/278 (16%)
Query: 3 PRGRRRPRPHRSEGARRSKNTLERTHSMKDKAGQKC-----KPIDVFDFPDNSDVSSIGR 57
PR R PR H S+G R N + + + D+ G+ +D D+ + S R
Sbjct: 13 PRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRR 72
Query: 58 LGENEKDEETYETFDPPLHSTA---IYADEEE-------FSKHCGLSLSSTPPGKEAKRS 107
G + +E+ + HS + Y D + +S H S R
Sbjct: 73 SGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRE 132
Query: 108 SDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRT 167
S ++ S + R P S S +S R K + + + T R +
Sbjct: 133 SPVGRKDSPHSRS---GSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSS 189
Query: 168 ---TASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIES-------------------- 204
+SS++ +KP+ +T K+ +++ + EK + ES
Sbjct: 190 GSAVSSSKVLDKPSR-LTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQ 248
Query: 205 ----QSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIW 238
+S T ++ D + +RSKAI S T +I ++
Sbjct: 249 PEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVY 286
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 41.6 bits (96), Expect = 0.001
Identities = 58/274 (21%), Positives = 110/274 (40%), Gaps = 16/274 (5%)
Query: 102 KEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEK----I 157
K + RSS N + + S KK ++ S+ SE E DT++ EK
Sbjct: 458 KSSSRSSGDKKNTSDRSSKTQASVKKEEKRS---SEKSEKKESKDTKKIEGKDEKNDNGA 514
Query: 158 STQRHEVIRTTASSE--LSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKIS 215
S Q E I+ + + S+ P V +T +PS I +SK +++ +
Sbjct: 515 SGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLD 574
Query: 216 HDKRKKSRSKAI-----GSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIE 270
+ K R K I + H+ E ++ + + E E+ E + I
Sbjct: 575 KKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIR 634
Query: 271 SKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRL 330
+ + + ++ + K+ +E L+R+ ++ + K+ +R+ ++EL R
Sbjct: 635 EREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQ 694
Query: 331 EPQLKQLQTKYDELKERK--SSLRNAAYFLSNLK 362
+ QL+ Q K + LK + R+ Y+ N K
Sbjct: 695 QQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKK 728
Score = 29.3 bits (64), Expect = 6.9
Identities = 50/249 (20%), Positives = 105/249 (42%), Gaps = 34/249 (13%)
Query: 116 SEIESVKISAKK----PGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASS 171
+E+ IS +K P +K +D +S S +K S TQ SS
Sbjct: 430 TELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSS 489
Query: 172 ELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDT 231
E SEK T K G + +N A S++ KK +++K+ SK+ G
Sbjct: 490 EKSEKKESKDTKKIEG-----KDEKNDNGASGQTSESIKKS----EEKKRISSKSPG--- 537
Query: 232 SDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATF-------YVN 284
H+ + K + +EK H +++ + + K + +
Sbjct: 538 ----HMVILDQTKGDHCRPSR--RGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEK 591
Query: 285 VKEQFIK--MLKESQMLTNLKRKNAKMISDIEKK---RQRMIEVQDELLRLEPQLKQLQT 339
+KEQ ++ +++ ++ ++ + + I++ E++ R R+I ++E RL+ + ++L+
Sbjct: 592 MKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEI 651
Query: 340 KYDELKERK 348
+ +L+ +
Sbjct: 652 ERQKLERER 660
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 41.6 bits (96), Expect = 0.001
Identities = 58/274 (21%), Positives = 110/274 (40%), Gaps = 16/274 (5%)
Query: 102 KEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEK----I 157
K + RSS N + + S KK ++ S+ SE E DT++ EK
Sbjct: 476 KSSSRSSGDKKNTSDRSSKTQASVKKEEKRS---SEKSEKKESKDTKKIEGKDEKNDNGA 532
Query: 158 STQRHEVIRTTASSE--LSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKIS 215
S Q E I+ + + S+ P V +T +PS I +SK +++ +
Sbjct: 533 SGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLD 592
Query: 216 HDKRKKSRSKAI-----GSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIE 270
+ K R K I + H+ E ++ + + E E+ E + I
Sbjct: 593 KKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIR 652
Query: 271 SKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRL 330
+ + + ++ + K+ +E L+R+ ++ + K+ +R+ ++EL R
Sbjct: 653 EREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQ 712
Query: 331 EPQLKQLQTKYDELKERK--SSLRNAAYFLSNLK 362
+ QL+ Q K + LK + R+ Y+ N K
Sbjct: 713 QQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKK 746
Score = 29.3 bits (64), Expect = 6.9
Identities = 50/249 (20%), Positives = 105/249 (42%), Gaps = 34/249 (13%)
Query: 116 SEIESVKISAKK----PGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASS 171
+E+ IS +K P +K +D +S S +K S TQ SS
Sbjct: 448 TELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSS 507
Query: 172 ELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDT 231
E SEK T K G + +N A S++ KK +++K+ SK+ G
Sbjct: 508 EKSEKKESKDTKKIEG-----KDEKNDNGASGQTSESIKKS----EEKKRISSKSPG--- 555
Query: 232 SDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATF-------YVN 284
H+ + K + +EK H +++ + + K + +
Sbjct: 556 ----HMVILDQTKGDHCRPSR--RGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEK 609
Query: 285 VKEQFIK--MLKESQMLTNLKRKNAKMISDIEKK---RQRMIEVQDELLRLEPQLKQLQT 339
+KEQ ++ +++ ++ ++ + + I++ E++ R R+I ++E RL+ + ++L+
Sbjct: 610 MKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEI 669
Query: 340 KYDELKERK 348
+ +L+ +
Sbjct: 670 ERQKLERER 678
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 41.2 bits (95), Expect = 0.002
Identities = 81/340 (23%), Positives = 137/340 (40%), Gaps = 24/340 (7%)
Query: 59 GENEKDEETYETFDPPLHST-AIYADEEEFSKHCGLSLSSTPPGKEAKRSSD--TSGNEA 115
G N E + + HST + AD + G + P K+ K D T E
Sbjct: 388 GNNTYKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFP-KKLKEEHDRCTLKQEN 446
Query: 116 SEIESVKISAKKPGRKL-RPISDDSESIEESDTRRKVKSAE-KISTQRHEVIRTTAS-SE 172
E +V + KK +L R + +E V+S E K T R+ + + E
Sbjct: 447 EEKTNVNMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTPNQDFHNHEE 506
Query: 173 LSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTS 232
+ + E+ K + Q +N +E ++K K KI+ + + K I +
Sbjct: 507 VKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNA-ALEKCIKLNEE 565
Query: 233 DIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKV------CKAAIATFYVNVK 286
I + +D+K N L E ++++E+++ AAI+ NVK
Sbjct: 566 MITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVK 625
Query: 287 EQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKE 346
+ + LK + T + KM SDI E++D+ L QL ++Q K++ LK+
Sbjct: 626 TE--RNLKLALERTQDISEQVKMSSDIS-------EIEDKNXFLTEQLSKMQIKFNTLKD 676
Query: 347 RKSSLRNAAYFLS-NLKQLYQDYSDVQAQEPNVKETYDSS 385
+ R+ S L+ + D S Q Q +KE Y S+
Sbjct: 677 KFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSA 716
Score = 33.9 bits (76), Expect = 0.28
Identities = 53/244 (21%), Positives = 106/244 (43%), Gaps = 44/244 (18%)
Query: 114 EASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSEL 173
E + + S + K+ +KL + ES + K +E + T+R+ + + ++
Sbjct: 584 ENTRLNSELLKEKESKKKLEA---EIESYQSRLAAAISKHSENVKTERNLKLALERTQDI 640
Query: 174 SEKPAESVTSKKTGPLSAQPSVEKENLAIESQ-SKTQKKGKISHDKRKKSRS----KAIG 228
SE+ S S +E +N + Q SK Q K DK +K+R K++
Sbjct: 641 SEQVKMS---------SDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLA 691
Query: 229 SDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQ 288
+T +D+ + + E ++ + Q E+KV K+ + V+E+
Sbjct: 692 LETVQ------------NDLSQTQQQIKEMKEMY----QSAEAKVSKSTGK--WNCVEER 733
Query: 289 FIKMLKESQML------TNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYD 342
++ +E+ L + K + +++ +I++ IE + + L LE + K+L +YD
Sbjct: 734 ICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRG---FIESRKKDLMLEEKNKKLMNEYD 790
Query: 343 ELKE 346
LKE
Sbjct: 791 HLKE 794
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 41.2 bits (95), Expect = 0.002
Identities = 81/340 (23%), Positives = 137/340 (40%), Gaps = 24/340 (7%)
Query: 59 GENEKDEETYETFDPPLHST-AIYADEEEFSKHCGLSLSSTPPGKEAKRSSD--TSGNEA 115
G N E + + HST + AD + G + P K+ K D T E
Sbjct: 388 GNNTYKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFP-KKLKEEHDRCTLKQEN 446
Query: 116 SEIESVKISAKKPGRKL-RPISDDSESIEESDTRRKVKSAE-KISTQRHEVIRTTAS-SE 172
E +V + KK +L R + +E V+S E K T R+ + + E
Sbjct: 447 EEKTNVNMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTPNQDFHNHEE 506
Query: 173 LSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTS 232
+ + E+ K + Q +N +E ++K K KI+ + + K I +
Sbjct: 507 VKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNA-ALEKCIKLNEE 565
Query: 233 DIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKV------CKAAIATFYVNVK 286
I + +D+K N L E ++++E+++ AAI+ NVK
Sbjct: 566 MITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVK 625
Query: 287 EQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKE 346
+ + LK + T + KM SDI E++D+ L QL ++Q K++ LK+
Sbjct: 626 TE--RNLKLALERTQDISEQVKMSSDIS-------EIEDKNXFLTEQLSKMQIKFNTLKD 676
Query: 347 RKSSLRNAAYFLS-NLKQLYQDYSDVQAQEPNVKETYDSS 385
+ R+ S L+ + D S Q Q +KE Y S+
Sbjct: 677 KFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSA 716
Score = 33.9 bits (76), Expect = 0.28
Identities = 53/244 (21%), Positives = 106/244 (43%), Gaps = 44/244 (18%)
Query: 114 EASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSEL 173
E + + S + K+ +KL + ES + K +E + T+R+ + + ++
Sbjct: 584 ENTRLNSELLKEKESKKKLEA---EIESYQSRLAAAISKHSENVKTERNLKLALERTQDI 640
Query: 174 SEKPAESVTSKKTGPLSAQPSVEKENLAIESQ-SKTQKKGKISHDKRKKSRS----KAIG 228
SE+ S S +E +N + Q SK Q K DK +K+R K++
Sbjct: 641 SEQVKMS---------SDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLA 691
Query: 229 SDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQ 288
+T +D+ + + E ++ + Q E+KV K+ + V+E+
Sbjct: 692 LETVQ------------NDLSQTQQQIKEMKEMY----QSAEAKVSKSTGK--WNCVEER 733
Query: 289 FIKMLKESQML------TNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYD 342
++ +E+ L + K + +++ +I++ IE + + L LE + K+L +YD
Sbjct: 734 ICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRG---FIESRKKDLMLEEKNKKLMNEYD 790
Query: 343 ELKE 346
LKE
Sbjct: 791 HLKE 794
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 41.2 bits (95), Expect = 0.002
Identities = 41/167 (24%), Positives = 74/167 (44%), Gaps = 25/167 (14%)
Query: 83 DEEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASEIESVKISAKKPGRKLR--------- 133
D ++ SK ++ K+ K+ ++++ E+ + + + KK +KL+
Sbjct: 305 DAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTK 364
Query: 134 --PISDDSESIEESDTR---RKVKSAEKISTQRHEVIRTTASSELSEKPAESVTS----- 183
P S D+ES + D R R +K A K ++ + + T S++ SE ES S
Sbjct: 365 KYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTD-SESELESKESQKDEK 423
Query: 184 --KKTGPLSAQPSVEKENLAIESQSKTQ---KKGKISHDKRKKSRSK 225
KK + SV+ + + ++ S+ + KKGK K KK K
Sbjct: 424 KDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKK 470
Score = 35.4 bits (80), Expect = 0.097
Identities = 68/297 (22%), Positives = 119/297 (40%), Gaps = 31/297 (10%)
Query: 57 RLGENEKDEETY--ETFDPPLHSTAIYADEEEFSKHCGLSLSSTPPGK-EAKRSSDTSGN 113
+L E +K + +F L IY E + L S T K E K+S D G
Sbjct: 65 KLEEGQKPAHKWIRHSFRKILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGG 124
Query: 114 EASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSEL 173
+K +KK G + +S+ I E T+R+ ++ + HE ++ S
Sbjct: 125 TP-----LKKDSKKKGGSYAT-NPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSS 178
Query: 174 SEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSD 233
SE ES SK +Q +K++ ++ T+ ++ K+ RSK S+
Sbjct: 179 SETNPESQNSKTVSKNCSQK--DKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISE 236
Query: 234 IVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKML 293
I C E LN+ + L Q ES A + + N + + L
Sbjct: 237 I----CSE-------NSLNV-----DFLMLVGQSDDESINFDAWLRNYSQNNSKNY--SL 278
Query: 294 KESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSS 350
K ++ +KNAK SD E + + + + + +++ +K+ K D K+ +S+
Sbjct: 279 KYTKYTKKDTKKNAKKSSDAESEDSK--DAKKDSKKVKKNVKKDDKKKDVKKDTEST 333
Score = 34.3 bits (77), Expect = 0.22
Identities = 31/142 (21%), Positives = 61/142 (42%), Gaps = 19/142 (13%)
Query: 102 KEAKRSSDTSGNEASEI----ESVKISAKKPGRKLRPISDDSESIE-------------E 144
K AK+SSD ++ + + VK + KK +K + + D+ES + +
Sbjct: 290 KNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKK-KDVKKDTESTDAESGDSKDERKDTK 348
Query: 145 SDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAESVTSKKTGPL-SAQPSVEKENLAIE 203
D ++ K +K T+++ T S + + +S KK + +K + +
Sbjct: 349 KDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTD 408
Query: 204 SQSKTQKKGKISHDKRKKSRSK 225
S+S+ + K +K+ K SK
Sbjct: 409 SESELESKESQKDEKKDKKDSK 430
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 41.2 bits (95), Expect = 0.002
Identities = 62/330 (18%), Positives = 147/330 (44%), Gaps = 19/330 (5%)
Query: 102 KEAKRSSDTSGNEASEIESVKISAKKPGRKL-------RPISDDSESIEESDTRRKVKSA 154
++AK + S I +++ KK + R + D+ E + + A
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
Query: 155 E-KISTQRHEVIRTTASSELSEKPAESVTS-KKTGPLSAQPSVEKENLAIE--SQSKTQK 210
E K+ + E A + L ++ A+ + KK L S +E+L E +++K +K
Sbjct: 1080 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1139
Query: 211 KGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIE 270
+ + ++ + +++ DT D + ++ +E+ ++ ++ H+ +++
Sbjct: 1140 QKRDLGEELEALKTEL--EDTLDSTAT--QQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
Query: 271 SKVCKAAIATFYVNVKEQFIKMLKES--QMLTNLKRKNAKMISDIEKKRQRMIEVQDELL 328
K A A + + + K K + + L+++NA + ++ Q EV+ +
Sbjct: 1196 EMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK 1255
Query: 329 RLEPQLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLP 388
+LE Q+++LQ+K + + ++ L + + L N + + +A+ +K D +SL
Sbjct: 1256 KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLN-EAEGKAIKLAKDVASLS 1314
Query: 389 ALLFKARTLLGAESHLR-NINHQLEKLLDQ 417
+ L + LL E+ + N++ +L +L ++
Sbjct: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEEE 1344
Score = 34.3 bits (77), Expect = 0.22
Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 11/95 (11%)
Query: 299 LTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLR------ 352
L++ K+K S +E + Q E+ L Q ++ YD+L++ K+ L+
Sbjct: 1373 LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
Query: 353 -----NAAYFLSNLKQLYQDYSDVQAQEPNVKETY 382
N +SNL++ + + + A+E N+ Y
Sbjct: 1433 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1467
Score = 33.5 bits (75), Expect = 0.37
Identities = 69/320 (21%), Positives = 127/320 (39%), Gaps = 52/320 (16%)
Query: 105 KRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEV 164
K ++D +G E + K + +KL + +S R + + +K+ ++EV
Sbjct: 1231 KENADLAG-ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1289
Query: 165 IRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRS 224
T +E A + +K LS+Q +E L Q +T++K +S R+
Sbjct: 1290 ESVTGMLNEAEGKAIKL-AKDVASLSSQLQDTQELL----QEETRQKLNVSTKLRQLEEE 1344
Query: 225 KAIGSDTSDIVHIWCPEGMKTSD-----IKELNIVLPEFEKTHLEHQQRIESKVCKAAIA 279
+ D D E M+ I LNI L + +K + +E+
Sbjct: 1345 RNSLQDQLD-------EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA-------- 1389
Query: 280 TFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELL-------RLEP 332
++E + KE + LT + A +EK + R+ + D+L+ +L
Sbjct: 1390 -----LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS 1444
Query: 333 QLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPALLF 392
L++ Q K+D+L + ++ S+ +D ++ +A+E KET S AL
Sbjct: 1445 NLEKKQRKFDQLLAEEKNI-------SSKYADERDRAEAEARE---KETKALSLARAL-- 1492
Query: 393 KARTLLGAESHLRNINHQLE 412
L A+ L N L+
Sbjct: 1493 --EEALEAKEELERTNKMLK 1510
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 41.2 bits (95), Expect = 0.002
Identities = 62/330 (18%), Positives = 147/330 (44%), Gaps = 19/330 (5%)
Query: 102 KEAKRSSDTSGNEASEIESVKISAKKPGRKL-------RPISDDSESIEESDTRRKVKSA 154
++AK + S I +++ KK + R + D+ E + + A
Sbjct: 1027 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1086
Query: 155 E-KISTQRHEVIRTTASSELSEKPAESVTS-KKTGPLSAQPSVEKENLAIE--SQSKTQK 210
E K+ + E A + L ++ A+ + KK L S +E+L E +++K +K
Sbjct: 1087 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1146
Query: 211 KGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIE 270
+ + ++ + +++ DT D + ++ +E+ ++ ++ H+ +++
Sbjct: 1147 QKRDLGEELEALKTEL--EDTLDSTAT--QQELRAKREQEVTVLKKALDEETRSHEAQVQ 1202
Query: 271 SKVCKAAIATFYVNVKEQFIKMLKES--QMLTNLKRKNAKMISDIEKKRQRMIEVQDELL 328
K A A + + + K K + + L+++NA + ++ Q EV+ +
Sbjct: 1203 EMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK 1262
Query: 329 RLEPQLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLP 388
+LE Q+++LQ+K + + ++ L + + L N + + +A+ +K D +SL
Sbjct: 1263 KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLN-EAEGKAIKLAKDVASLS 1321
Query: 389 ALLFKARTLLGAESHLR-NINHQLEKLLDQ 417
+ L + LL E+ + N++ +L +L ++
Sbjct: 1322 SQLQDTQELLQEETRQKLNVSTKLRQLEEE 1351
Score = 34.3 bits (77), Expect = 0.22
Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 11/95 (11%)
Query: 299 LTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLR------ 352
L++ K+K S +E + Q E+ L Q ++ YD+L++ K+ L+
Sbjct: 1380 LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
Query: 353 -----NAAYFLSNLKQLYQDYSDVQAQEPNVKETY 382
N +SNL++ + + + A+E N+ Y
Sbjct: 1440 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1474
Score = 33.5 bits (75), Expect = 0.37
Identities = 69/320 (21%), Positives = 127/320 (39%), Gaps = 52/320 (16%)
Query: 105 KRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEV 164
K ++D +G E + K + +KL + +S R + + +K+ ++EV
Sbjct: 1238 KENADLAG-ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1296
Query: 165 IRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRS 224
T +E A + +K LS+Q +E L Q +T++K +S R+
Sbjct: 1297 ESVTGMLNEAEGKAIKL-AKDVASLSSQLQDTQELL----QEETRQKLNVSTKLRQLEEE 1351
Query: 225 KAIGSDTSDIVHIWCPEGMKTSD-----IKELNIVLPEFEKTHLEHQQRIESKVCKAAIA 279
+ D D E M+ I LNI L + +K + +E+
Sbjct: 1352 RNSLQDQLD-------EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA-------- 1396
Query: 280 TFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELL-------RLEP 332
++E + KE + LT + A +EK + R+ + D+L+ +L
Sbjct: 1397 -----LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS 1451
Query: 333 QLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPALLF 392
L++ Q K+D+L + ++ S+ +D ++ +A+E KET S AL
Sbjct: 1452 NLEKKQRKFDQLLAEEKNI-------SSKYADERDRAEAEARE---KETKALSLARAL-- 1499
Query: 393 KARTLLGAESHLRNINHQLE 412
L A+ L N L+
Sbjct: 1500 --EEALEAKEELERTNKMLK 1517
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 41.2 bits (95), Expect = 0.002
Identities = 62/330 (18%), Positives = 147/330 (44%), Gaps = 19/330 (5%)
Query: 102 KEAKRSSDTSGNEASEIESVKISAKKPGRKL-------RPISDDSESIEESDTRRKVKSA 154
++AK + S I +++ KK + R + D+ E + + A
Sbjct: 1027 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1086
Query: 155 E-KISTQRHEVIRTTASSELSEKPAESVTS-KKTGPLSAQPSVEKENLAIE--SQSKTQK 210
E K+ + E A + L ++ A+ + KK L S +E+L E +++K +K
Sbjct: 1087 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1146
Query: 211 KGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIE 270
+ + ++ + +++ DT D + ++ +E+ ++ ++ H+ +++
Sbjct: 1147 QKRDLGEELEALKTEL--EDTLDSTAT--QQELRAKREQEVTVLKKALDEETRSHEAQVQ 1202
Query: 271 SKVCKAAIATFYVNVKEQFIKMLKES--QMLTNLKRKNAKMISDIEKKRQRMIEVQDELL 328
K A A + + + K K + + L+++NA + ++ Q EV+ +
Sbjct: 1203 EMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK 1262
Query: 329 RLEPQLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLP 388
+LE Q+++LQ+K + + ++ L + + L N + + +A+ +K D +SL
Sbjct: 1263 KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLN-EAEGKAIKLAKDVASLS 1321
Query: 389 ALLFKARTLLGAESHLR-NINHQLEKLLDQ 417
+ L + LL E+ + N++ +L +L ++
Sbjct: 1322 SQLQDTQELLQEETRQKLNVSTKLRQLEEE 1351
Score = 34.3 bits (77), Expect = 0.22
Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 11/95 (11%)
Query: 299 LTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLR------ 352
L++ K+K S +E + Q E+ L Q ++ YD+L++ K+ L+
Sbjct: 1380 LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
Query: 353 -----NAAYFLSNLKQLYQDYSDVQAQEPNVKETY 382
N +SNL++ + + + A+E N+ Y
Sbjct: 1440 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1474
Score = 33.5 bits (75), Expect = 0.37
Identities = 69/320 (21%), Positives = 127/320 (39%), Gaps = 52/320 (16%)
Query: 105 KRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEV 164
K ++D +G E + K + +KL + +S R + + +K+ ++EV
Sbjct: 1238 KENADLAG-ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1296
Query: 165 IRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRS 224
T +E A + +K LS+Q +E L Q +T++K +S R+
Sbjct: 1297 ESVTGMLNEAEGKAIKL-AKDVASLSSQLQDTQELL----QEETRQKLNVSTKLRQLEEE 1351
Query: 225 KAIGSDTSDIVHIWCPEGMKTSD-----IKELNIVLPEFEKTHLEHQQRIESKVCKAAIA 279
+ D D E M+ I LNI L + +K + +E+
Sbjct: 1352 RNSLQDQLD-------EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA-------- 1396
Query: 280 TFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELL-------RLEP 332
++E + KE + LT + A +EK + R+ + D+L+ +L
Sbjct: 1397 -----LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS 1451
Query: 333 QLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPALLF 392
L++ Q K+D+L + ++ S+ +D ++ +A+E KET S AL
Sbjct: 1452 NLEKKQRKFDQLLAEEKNI-------SSKYADERDRAEAEARE---KETKALSLARAL-- 1499
Query: 393 KARTLLGAESHLRNINHQLE 412
L A+ L N L+
Sbjct: 1500 --EEALEAKEELERTNKMLK 1517
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 41.2 bits (95), Expect = 0.002
Identities = 62/330 (18%), Positives = 147/330 (44%), Gaps = 19/330 (5%)
Query: 102 KEAKRSSDTSGNEASEIESVKISAKKPGRKL-------RPISDDSESIEESDTRRKVKSA 154
++AK + S I +++ KK + R + D+ E + + A
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
Query: 155 E-KISTQRHEVIRTTASSELSEKPAESVTS-KKTGPLSAQPSVEKENLAIE--SQSKTQK 210
E K+ + E A + L ++ A+ + KK L S +E+L E +++K +K
Sbjct: 1080 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1139
Query: 211 KGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIE 270
+ + ++ + +++ DT D + ++ +E+ ++ ++ H+ +++
Sbjct: 1140 QKRDLGEELEALKTEL--EDTLDSTAT--QQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
Query: 271 SKVCKAAIATFYVNVKEQFIKMLKES--QMLTNLKRKNAKMISDIEKKRQRMIEVQDELL 328
K A A + + + K K + + L+++NA + ++ Q EV+ +
Sbjct: 1196 EMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK 1255
Query: 329 RLEPQLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLP 388
+LE Q+++LQ+K + + ++ L + + L N + + +A+ +K D +SL
Sbjct: 1256 KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLN-EAEGKAIKLAKDVASLS 1314
Query: 389 ALLFKARTLLGAESHLR-NINHQLEKLLDQ 417
+ L + LL E+ + N++ +L +L ++
Sbjct: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEEE 1344
Score = 34.3 bits (77), Expect = 0.22
Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 11/95 (11%)
Query: 299 LTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLR------ 352
L++ K+K S +E + Q E+ L Q ++ YD+L++ K+ L+
Sbjct: 1373 LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
Query: 353 -----NAAYFLSNLKQLYQDYSDVQAQEPNVKETY 382
N +SNL++ + + + A+E N+ Y
Sbjct: 1433 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1467
Score = 33.5 bits (75), Expect = 0.37
Identities = 69/320 (21%), Positives = 127/320 (39%), Gaps = 52/320 (16%)
Query: 105 KRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEV 164
K ++D +G E + K + +KL + +S R + + +K+ ++EV
Sbjct: 1231 KENADLAG-ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1289
Query: 165 IRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRS 224
T +E A + +K LS+Q +E L Q +T++K +S R+
Sbjct: 1290 ESVTGMLNEAEGKAIKL-AKDVASLSSQLQDTQELL----QEETRQKLNVSTKLRQLEEE 1344
Query: 225 KAIGSDTSDIVHIWCPEGMKTSD-----IKELNIVLPEFEKTHLEHQQRIESKVCKAAIA 279
+ D D E M+ I LNI L + +K + +E+
Sbjct: 1345 RNSLQDQLD-------EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA-------- 1389
Query: 280 TFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELL-------RLEP 332
++E + KE + LT + A +EK + R+ + D+L+ +L
Sbjct: 1390 -----LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS 1444
Query: 333 QLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPALLF 392
L++ Q K+D+L + ++ S+ +D ++ +A+E KET S AL
Sbjct: 1445 NLEKKQRKFDQLLAEEKNI-------SSKYADERDRAEAEARE---KETKALSLARAL-- 1492
Query: 393 KARTLLGAESHLRNINHQLE 412
L A+ L N L+
Sbjct: 1493 --EEALEAKEELERTNKMLK 1510
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 41.2 bits (95), Expect = 0.002
Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 20/159 (12%)
Query: 197 KENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLP 256
KE A+ + + +DKRKK KA DT H + + K+
Sbjct: 149 KERTALFEEISRSGELAQEYDKRKKEMVKA-EEDTQFNYHRKKNIAAERKEAKQ------ 201
Query: 257 EFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKK 316
EK + QR++ +V +A V+ Q K+ + L ++ A +IEK
Sbjct: 202 --EKEEADRYQRLKDEVVRA-------QVQLQLFKLYHNEVEIEKLNKELASKNKEIEKD 252
Query: 317 RQRMIEVQDELLRLEPQL----KQLQTKYDELKERKSSL 351
++RM +V+DEL + +L ++ Q E+KE+ S L
Sbjct: 253 KKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Score = 37.0 bits (84), Expect = 0.033
Identities = 62/335 (18%), Positives = 135/335 (40%), Gaps = 55/335 (16%)
Query: 24 LERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGENEKDE-ETYETFDPP-------L 75
L + + + K K + F++ ++++ + + EK+E + Y+ L
Sbjct: 164 LAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQL 223
Query: 76 HSTAIYADEEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASEIESVKISAKKPGRKLRPI 135
+Y +E E K L+ KE ++ E++ K K+ G+ +R
Sbjct: 224 QLFKLYHNEVEIEK---LNKELASKNKEIEKDKKRMDKVEDELKEKK---KELGKMMREQ 277
Query: 136 SDDSESIEESDTRRKVKSAEKISTQRH--EVIRTTASSELSEKPAESVTSKKTGPLSAQP 193
+ I+E D+ K + I + + I+ +++ S + A+ K+ G +
Sbjct: 278 QQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMD--- 334
Query: 194 SVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNI 253
+EKE L++E K + ++R + S++ G D +
Sbjct: 335 ELEKEMLSVE-------KARQEFEERMEEESQSQGRDLT--------------------- 366
Query: 254 VLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDI 313
E+ ++ R++ + K A AT + E+F + K Q +L+ + K +
Sbjct: 367 ----LEENQVKKYHRLKEEASKRA-ATLAQEL-EKFNRDQKADQDRLDLEER--KKVETE 418
Query: 314 EKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERK 348
K +Q++ E+++ R+E + + T L+E+K
Sbjct: 419 AKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQK 453
Score = 31.6 bits (70), Expect = 1.4
Identities = 42/223 (18%), Positives = 100/223 (44%), Gaps = 29/223 (13%)
Query: 166 RTTASSELSEKP--AESVTSKKTGPLSAQPSVE-----KENLAIESQSKTQKKGKISHDK 218
RT E+S A+ +K + A+ + K+N+A E + Q+K + D+
Sbjct: 151 RTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEA--DR 208
Query: 219 RKKSRSKAIGSDTS-DIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAA 277
++ + + + + + ++ E +I++LN L K + ++R++
Sbjct: 209 YQRLKDEVVRAQVQLQLFKLYHNE----VEIEKLNKELASKNKEIEKDKKRMDK------ 258
Query: 278 IATFYVNVKEQFIKMLKESQMLTN-LKRKNAKMISDIEKKRQRMIEVQD----ELLRLEP 332
+ K++ KM++E Q + +K K+ S++ +KR + I+ ++ ++ +LE
Sbjct: 259 VEDELKEKKKELGKMMREQQQIEKEIKEKD----SELNQKRPQYIKAKENTSHKIKKLEA 314
Query: 333 QLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQE 375
K LQ K+RK + + ++++ Q++ + +E
Sbjct: 315 AKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEE 357
>gi|110347568 centrosomal protein 152kDa [Homo sapiens]
Length = 1654
Score = 41.2 bits (95), Expect = 0.002
Identities = 66/288 (22%), Positives = 119/288 (41%), Gaps = 19/288 (6%)
Query: 102 KEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEE-SDTRRKVKSAEKISTQ 160
K+ +R+ + E +EI + + + +K S S++E + + +++ A+K
Sbjct: 403 KQLERNQEAIKLEKTEIINKLTRSLEESQKQCAHLLQSGSVQEVAQLQFQLQQAQKAHAM 462
Query: 161 RHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRK 220
+ + EL+E E + L PS + L IE G I K
Sbjct: 463 SANMNKAL-QEELTELKDEISLYESAAKLGIHPSDSEGELNIELTESYVDLG-IKKVNWK 520
Query: 221 KSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIAT 280
KS+ +I + + E + + ++ K HL Q + + K C I
Sbjct: 521 KSKVTSIVQEEDPNEELSKDEFILKLKAEVQRLLGSNSMKRHLVSQLQNDLKDCHKKIED 580
Query: 281 FYVNVKEQFIKMLKESQMLTNLKRKNA----KMISDIEKKRQRMIEVQDELLRLEPQLKQ 336
+ VK+ + E++ T+ K KN SD+ V+D++L L+ +++
Sbjct: 581 LH-QVKKDEKSIEVETKTDTSEKPKNQLWPESSTSDV---------VRDDILLLKNEIQV 630
Query: 337 LQTKYDELKERKSSLRNAAYFLSN-LKQLYQDYS-DVQAQEPNVKETY 382
LQ + ELKE + LRN L N ++Q+ QD+ D Q + TY
Sbjct: 631 LQQQNQELKETEGKLRNTNQDLCNQMRQMVQDFDHDKQEAVDRCERTY 678
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 40.8 bits (94), Expect = 0.002
Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Query: 100 PGKEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKIST 159
P E+ + ++ S E S ++ ++ G P + E E+SD+ + S+ +S
Sbjct: 336 PSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEE-DSSHTLSH 394
Query: 160 QRHEVIRTTASSELSEK---PAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISH 216
+ E A SE SE ES S + S+Q ++ + + ESQS+ +
Sbjct: 395 SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 454
Query: 217 DKRKKSRSKAIGSDT 231
D + SRSK + T
Sbjct: 455 DSQDSSRSKEDSNST 469
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 40.8 bits (94), Expect = 0.002
Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Query: 100 PGKEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKIST 159
P E+ + ++ S E S ++ ++ G P + E E+SD+ + S+ +S
Sbjct: 320 PSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEE-DSSHTLSH 378
Query: 160 QRHEVIRTTASSELSEK---PAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISH 216
+ E A SE SE ES S + S+Q ++ + + ESQS+ +
Sbjct: 379 SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 438
Query: 217 DKRKKSRSKAIGSDT 231
D + SRSK + T
Sbjct: 439 DSQDSSRSKEDSNST 453
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 40.8 bits (94), Expect = 0.002
Identities = 62/318 (19%), Positives = 140/318 (44%), Gaps = 31/318 (9%)
Query: 114 EASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSEL 173
+ + +E + + KK ++ + E I+E + R V ++ Q E T ++
Sbjct: 1454 QKAALELLSLDLKKRNQE---VDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQI 1510
Query: 174 SEKPAESVTSKKTGPLSAQP-SVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTS 232
E + T + L Q +EK++ IESQ +G++ K++ + + +
Sbjct: 1511 RELEKDRETQRNV--LEHQLLELEKKDQMIESQ-----RGQVQDLKKQLVTLECLALELE 1563
Query: 233 DIVH-IWCP-------EGMKTSDIKELNIVLPEFEKTHLEHQ---QRIESKVCKAAIATF 281
+ H + C EG + + L + + E+ E Q +I + +
Sbjct: 1564 ENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLAR 1623
Query: 282 YVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQ-LKQLQTK 340
+ ++Q +K +E + L+R+ + D+E++ Q ++ ++ + LE Q +Q +
Sbjct: 1624 ELQERDQEVKSQREQ--IEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKIL 1681
Query: 341 YDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPALL-FKARTLLG 399
++L++ K SLR L+ +QL Q+ ++ + + P+ + + +L K + +
Sbjct: 1682 EEDLEQIKLSLRERGRELTTQRQLMQERAE-EGKGPSKAQRGSLEHMKLILRDKEKEVEC 1740
Query: 400 AESHLRNINHQLEKLLDQ 417
+ H+ H+L++L DQ
Sbjct: 1741 QQEHI----HELQELKDQ 1754
Score = 32.3 bits (72), Expect = 0.82
Identities = 54/266 (20%), Positives = 114/266 (42%), Gaps = 31/266 (11%)
Query: 102 KEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEE-----SDTRRKVKSAEK 156
+EAKR + E E++ +L+ + D + + E S + ++S+
Sbjct: 715 QEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLF 774
Query: 157 ISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISH 216
+ Q++ VI T E ++VT K Q V L ++++ ++Q + +
Sbjct: 775 EAQQQNSVIEVTKGQ--LEVQIQTVTQAKE---VIQGEVRCLKLELDTE-RSQAEQERDA 828
Query: 217 DKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKV--C 274
R+ ++++ G E K + KE+N + ++EK HQQ + +
Sbjct: 829 AARQLAQAEQEGKTAL--------EQQKAAHEKEVNQLREKWEKERSWHQQELAKALESL 880
Query: 275 KAAIATFYVNVKEQFIKM----LKESQMLTNLKRKNAKMISDIEKKR----QRMIEVQDE 326
+ + +KEQ +M + + T + +M + EK+R + +++ Q E
Sbjct: 881 EREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKE 940
Query: 327 LLRLEPQLKQLQ--TKYDELKERKSS 350
L QL++L+ K +LKE++++
Sbjct: 941 LADASQQLERLRQDMKVQKLKEQETT 966
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 40.8 bits (94), Expect = 0.002
Identities = 47/221 (21%), Positives = 82/221 (37%), Gaps = 4/221 (1%)
Query: 14 SEGARRSKNTLERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGENEKDEETYETFDP 73
S + S N+ + + S + D D D+SD S + ++ ++ D
Sbjct: 956 SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015
Query: 74 PLHSTAIYADEEEFSKHCGLSLSSTPPGKEAKRS-SDTSGNEASEIESVKISAKKPGRKL 132
S + + + S S S+ + S S S N + +S S
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075
Query: 133 RPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQ 192
SD SES + SD+ S++ S+ + ++ SS+ S+ S +S + +
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133
Query: 193 PSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSD 233
S + N + S S S D S S + SD+SD
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS-SDSSDSSD 1173
Score = 39.3 bits (90), Expect = 0.007
Identities = 43/194 (22%), Positives = 73/194 (37%), Gaps = 13/194 (6%)
Query: 45 DFPDNSDVSSIGRLGENEKDEETYETFDPPLHS----TAIYADEEEFSKHCGLSLSSTPP 100
D DNSD S + ++ ++ D S ++ +D + S S SS
Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 101 GKEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQ 160
++ SSD+S + +S+ +S S SD S+S SD+ S+
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSD-- 766
Query: 161 RHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDK-R 219
++ SS+ S+ S +S ++ S + N + S S S D
Sbjct: 767 ------SSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDS 820
Query: 220 KKSRSKAIGSDTSD 233
S + SD+SD
Sbjct: 821 SNSSDSSNSSDSSD 834
Score = 38.9 bits (89), Expect = 0.009
Identities = 45/222 (20%), Positives = 79/222 (35%), Gaps = 2/222 (0%)
Query: 14 SEGARRSKNTLERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGENEKDEETYETFDP 73
S+ + S ++ S + D D D+SD S ++ ++ ++ D
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138
Query: 74 PLHSTAIYADEEEFSKHCGLSLSSTPPGKEAKRS-SDTSGNEASEIESVKISAKKPGRKL 132
S + + E S S S+ + S S S N + +S S
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 133 RPISDDSESIEESDTRRKVKSAEKI-STQRHEVIRTTASSELSEKPAESVTSKKTGPLSA 191
SD S+S + SD+ S++ S+ + ++ SS+ S+ S +S + +
Sbjct: 1199 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDS 1258
Query: 192 QPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSD 233
S N +SQSK+ D S TSD
Sbjct: 1259 SDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300
Score = 37.0 bits (84), Expect = 0.033
Identities = 42/197 (21%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 48 DNSDVSSIGRLGENEKDEETYETFDPPLHSTAIYADEEEF----------SKHCGLSLSS 97
D++D S G+ + D ++ ++ + S + +D + S S S
Sbjct: 535 DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594
Query: 98 TPPGKEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSES-IEESDTRRKVKSAEK 156
+ + SSD+S + S S +K K S DS+S + SD+ S
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654
Query: 157 ISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISH 216
S+ ++ SS+ S+ S +S + + S + N + ES + S
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN-SSESSDSSDSSDSDSS 713
Query: 217 DKRKKSRSKAIGSDTSD 233
D S S + SD+S+
Sbjct: 714 DSSDSSNSNSSDSDSSN 730
Score = 35.4 bits (80), Expect = 0.097
Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 10/193 (5%)
Query: 45 DFPDNSDVSSIGRLGENEKDEETYETFDPPLHSTAIYADEEEFSKHCGLSLSSTPPGKEA 104
D D+SD S ++ ++ E+ D S + +D + S S SS ++
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS--SDSSDSSDSSDSSDSSD--SSDS 1114
Query: 105 KRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKI----STQ 160
SSD+S N + +S S SD SES + SD+ S++ S+
Sbjct: 1115 SDSSDSS-NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSD 1173
Query: 161 RHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRK 220
+ ++ SS+ S+ S +S + + S + + + S S S D +
Sbjct: 1174 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNE 1233
Query: 221 KSRSKAIGSDTSD 233
S S + SD+SD
Sbjct: 1234 SSDS-SDSSDSSD 1245
Score = 33.5 bits (75), Expect = 0.37
Identities = 44/206 (21%), Positives = 77/206 (37%), Gaps = 9/206 (4%)
Query: 32 DKAGQKCKPIDVFDFPDNSDVSSIGRLGENEKDEETYETFDPPLHSTAIYADEEEFSKHC 91
D G + D +NSD + G G ++ D+ S + +D + S
Sbjct: 506 DSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSD----SGKGKSDSSDSDSSDSSNSS 561
Query: 92 GLSLSSTPPGKEAKRSSDT--SGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRR 149
S SS ++ SSD+ S +++S+ S SD S+S + SD+
Sbjct: 562 DSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 621
Query: 150 KVKSAEKISTQRHEVIRTTASSE--LSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSK 207
+ K + + + SS+ S+ S +S + ++ S + + + S S
Sbjct: 622 SKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSS 681
Query: 208 TQKKGKISHDKRKKSRSKAIGSDTSD 233
S D S S SD+SD
Sbjct: 682 DSSNSSDSSDSSDSSNSSE-SSDSSD 706
Score = 32.7 bits (73), Expect = 0.63
Identities = 41/192 (21%), Positives = 71/192 (36%), Gaps = 11/192 (5%)
Query: 42 DVFDFPDNSDVSSIGRLGENEKDEETYETFDPPLHSTAIYADEEEFSKHCGLSLSSTPPG 101
D D D+SD S ++ + ++ D S + + + S S SS
Sbjct: 766 DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN--S 823
Query: 102 KEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQR 161
++ SSD+S + S +S S G DS+S SD+ S++ +
Sbjct: 824 SDSSNSSDSSDSSNSS-DSSDSSDSSDG-------SDSDSSNRSDSSNSSDSSDSSDSSN 875
Query: 162 HEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKK 221
++ S S ++S S + + S + + S S + S D
Sbjct: 876 SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNS 935
Query: 222 SRSKAIGSDTSD 233
S S + SD+SD
Sbjct: 936 SDS-SNSSDSSD 946
Score = 31.6 bits (70), Expect = 1.4
Identities = 40/192 (20%), Positives = 74/192 (38%), Gaps = 8/192 (4%)
Query: 45 DFPDNSDVSSIGRLGENEKDEETYETFDPPLHSTAIYADEEEFSKHCGLSLSSTPPGKEA 104
D P++SD S+ +E D + D +S DE + + + S + ++
Sbjct: 463 DDPNSSDESNGNDDANSESDNNSSSRGDASYNS-----DESKDNGNGSDSKGAEDDDSDS 517
Query: 105 K---RSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQR 161
+SD++GN + + S G+ SD S+S SD+ S S
Sbjct: 518 TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577
Query: 162 HEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKK 221
+ + + S S S +S + + S + + + S SK+ S
Sbjct: 578 SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSD 637
Query: 222 SRSKAIGSDTSD 233
S+S + S++SD
Sbjct: 638 SKSDSSDSNSSD 649
Score = 31.6 bits (70), Expect = 1.4
Identities = 42/220 (19%), Positives = 84/220 (38%), Gaps = 11/220 (5%)
Query: 14 SEGARRSKNTLERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGENEKDEETYETFDP 73
SE + S ++ + D + D + D+SD S+ ++ + ++ D
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758
Query: 74 PLHSTAIYADEEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASEIESVKISAKKPGRKLR 133
S + + + S S +S+ + S + + +S+ + S+
Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD---- 814
Query: 134 PISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQP 193
S DS+S SD+ S++ S+ + ++ SS+ S+ + S S + +
Sbjct: 815 --SSDSDSSNSSDSSNSSDSSD--SSNSSDSSDSSDSSDGSDSDS-SNRSDSSNSSDSSD 869
Query: 194 SVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSD 233
S + N + S S + S D S S SD+SD
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS--DSDSSD 907
>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 40.8 bits (94), Expect = 0.002
Identities = 61/284 (21%), Positives = 121/284 (42%), Gaps = 23/284 (8%)
Query: 107 SSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIR 166
+ DT A E++ ++ K +L S++ + I+ + +++ EK + I
Sbjct: 242 AEDTKVRSAEELKEMQDKVIKLQEEL---SENDKKIKALN--HEIEELEKRKDKETGGIL 296
Query: 167 TTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIE-SQSKTQKKGKISHDKRKKSRSK 225
+ L+E A+ V +K ++K+NLA E S+ K +K + K ++ K
Sbjct: 297 RSLEDALAE--AQRVNTKSQSAFD----LKKKNLACEESKRKELEKNMVEDSKTLAAKEK 350
Query: 226 AIGSDTSDIVHIWCPEGMKTSDI-----KELNIVLPEFEKTHLEHQQRIESKV--CKAAI 278
+ T D +H K ++ + N V + + ++ CK I
Sbjct: 351 EVKKIT-DGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMMACKNDI 409
Query: 279 ATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQ 338
+ K+ +K+ Q L N + + KM S K ++ + V+ +LE ++K+L
Sbjct: 410 SKAQTEAKQAQMKLKHAQQELKNKQAEVKKMDSGYRKDQEALEAVKRLKEKLEAEMKKL- 468
Query: 339 TKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETY 382
Y+E KE +S L ++ +L + Y + A+ PN++ Y
Sbjct: 469 -NYEENKE-ESLLEKRRQLSRDIGRLKETYEALLARFPNLRFAY 510
>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 40.8 bits (94), Expect = 0.002
Identities = 61/284 (21%), Positives = 121/284 (42%), Gaps = 23/284 (8%)
Query: 107 SSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIR 166
+ DT A E++ ++ K +L S++ + I+ + +++ EK + I
Sbjct: 242 AEDTKVRSAEELKEMQDKVIKLQEEL---SENDKKIKALN--HEIEELEKRKDKETGGIL 296
Query: 167 TTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIE-SQSKTQKKGKISHDKRKKSRSK 225
+ L+E A+ V +K ++K+NLA E S+ K +K + K ++ K
Sbjct: 297 RSLEDALAE--AQRVNTKSQSAFD----LKKKNLACEESKRKELEKNMVEDSKTLAAKEK 350
Query: 226 AIGSDTSDIVHIWCPEGMKTSDI-----KELNIVLPEFEKTHLEHQQRIESKV--CKAAI 278
+ T D +H K ++ + N V + + ++ CK I
Sbjct: 351 EVKKIT-DGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMMACKNDI 409
Query: 279 ATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQ 338
+ K+ +K+ Q L N + + KM S K ++ + V+ +LE ++K+L
Sbjct: 410 SKAQTEAKQAQMKLKHAQQELKNKQAEVKKMDSGYRKDQEALEAVKRLKEKLEAEMKKL- 468
Query: 339 TKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETY 382
Y+E KE +S L ++ +L + Y + A+ PN++ Y
Sbjct: 469 -NYEENKE-ESLLEKRRQLSRDIGRLKETYEALLARFPNLRFAY 510
>gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 40.8 bits (94), Expect = 0.002
Identities = 61/284 (21%), Positives = 121/284 (42%), Gaps = 23/284 (8%)
Query: 107 SSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIR 166
+ DT A E++ ++ K +L S++ + I+ + +++ EK + I
Sbjct: 242 AEDTKVRSAEELKEMQDKVIKLQEEL---SENDKKIKALN--HEIEELEKRKDKETGGIL 296
Query: 167 TTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIE-SQSKTQKKGKISHDKRKKSRSK 225
+ L+E A+ V +K ++K+NLA E S+ K +K + K ++ K
Sbjct: 297 RSLEDALAE--AQRVNTKSQSAFD----LKKKNLACEESKRKELEKNMVEDSKTLAAKEK 350
Query: 226 AIGSDTSDIVHIWCPEGMKTSDI-----KELNIVLPEFEKTHLEHQQRIESKV--CKAAI 278
+ T D +H K ++ + N V + + ++ CK I
Sbjct: 351 EVKKIT-DGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMMACKNDI 409
Query: 279 ATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQ 338
+ K+ +K+ Q L N + + KM S K ++ + V+ +LE ++K+L
Sbjct: 410 SKAQTEAKQAQMKLKHAQQELKNKQAEVKKMDSGYRKDQEALEAVKRLKEKLEAEMKKL- 468
Query: 339 TKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETY 382
Y+E KE +S L ++ +L + Y + A+ PN++ Y
Sbjct: 469 -NYEENKE-ESLLEKRRQLSRDIGRLKETYEALLARFPNLRFAY 510
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/258 (23%), Positives = 107/258 (41%), Gaps = 44/258 (17%)
Query: 148 RRKVKSAEKISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSK 207
+R S E++ + E E +++T K AQ N+AI+SQ
Sbjct: 59 KRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQD----RNIAIQSQF- 113
Query: 208 TQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQ 267
T+ K ++ +KR R+ S + + T D+K LN L E T E Q
Sbjct: 114 TRTKEELEAEKRDLIRTNERLSQELEYL---------TEDVKRLNEKLKESNTTKGELQL 164
Query: 268 RIESKVCKAAIATFYVNVKEQFIKML--KESQMLTNLKRKNAKMISDIEKKRQRMIEVQ- 324
+++ + EQ ++L + + + T LK K ++++ +K ++E++
Sbjct: 165 KLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKC 224
Query: 325 ------DELLRLEPQLKQLQT--------------KYDELKERKSSLR-------NAAYF 357
+E+ RLE Q+ L+T K E KE+++S+ NA
Sbjct: 225 NLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIK 284
Query: 358 LSNLKQLYQDYSDVQAQE 375
LSNL + D S+ ++ E
Sbjct: 285 LSNLYKSAADDSEAKSNE 302
Score = 33.1 bits (74), Expect = 0.48
Identities = 48/247 (19%), Positives = 103/247 (41%), Gaps = 35/247 (14%)
Query: 141 SIEESDTRRKVKSAEKISTQRHEVIRTTAS----SELSEKPAESVTSKKTGPLSAQPSVE 196
S +E T+R + E+I + E+ R+ AS L + E + +T + Q ++
Sbjct: 1359 SEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLD 1418
Query: 197 KENLAIESQSKT-------QKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIK 249
+ + I+ + KT ++ K +++ K + K + + + + +++
Sbjct: 1419 AKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQ-EQHVSVQEMQ 1477
Query: 250 ELNIVLPEFEKTHLEHQQRIES-KVCKAAIATFYVNVKEQFIKMLKE------------- 295
EL L + E + ++E+ + + T N++EQ +++ E
Sbjct: 1478 ELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTT 1537
Query: 296 -----SQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQ----LQTKYDELKE 346
Q +T + K K I + K + V+D+L + +LKQ L + DEL
Sbjct: 1538 QEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDV 1597
Query: 347 RKSSLRN 353
R ++L++
Sbjct: 1598 RITALKS 1604
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 40.4 bits (93), Expect = 0.003
Identities = 57/279 (20%), Positives = 113/279 (40%), Gaps = 25/279 (8%)
Query: 148 RRKVKSAEK---ISTQRHEVIRTTASSELSEKP---AESVTSKKTGPLSAQ-PSVEKENL 200
+ KV+ EK ++ R E++RTTA + + E K T LS Q + E
Sbjct: 324 KAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARC 383
Query: 201 AIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEK 260
++E + K ++K R++ + + + + E + ++ N++ E +K
Sbjct: 384 SLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMH--NVLQAELDK 441
Query: 261 THLEHQQ------RIESKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIE 314
QQ + K+C+A A +KE ++ E +K++N + S E
Sbjct: 442 LTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEE-----MKKENNLLKSHSE 496
Query: 315 KKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQ 374
+K + + ++ EL ++ L Q Q +E+K + +S L ++ ++
Sbjct: 497 QKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKL 556
Query: 375 EPNVKETYDSSSLPALLFKARTLLGAESHLRNINHQLEK 413
+ V + L K R E H+ +N +L K
Sbjct: 557 KLAVADLEKQRDCSQDLLKKR-----EHHIEQLNDKLSK 590
Score = 36.2 bits (82), Expect = 0.057
Identities = 66/312 (21%), Positives = 131/312 (41%), Gaps = 38/312 (12%)
Query: 110 TSGNEASEIESV-KISAKKPG--RKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIR 166
T ++ S +E V K++AK+ R++ ++ + ++E + K + A ++ E+
Sbjct: 2600 TKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEI-- 2657
Query: 167 TTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKA 226
++ +L E E+ KK+ + VEKE E ++ Q + H+ KK ++
Sbjct: 2658 KSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLR---LHEAEKKHQALL 2714
Query: 227 IGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVK 286
+ ++ V I TS K Q++E + K++ K
Sbjct: 2715 LDTNKQYEVEIQTYREKLTS-------------KEECLSSQKLEIDLLKSS--------K 2753
Query: 287 EQFIKMLKES-QMLTNLKR---KNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYD 342
E+ LK + Q+L LK+ N K ++ ++K+ +R Q ++ L KQL+ + +
Sbjct: 2754 EELNNSLKATTQILEELKKTKMDNLKYVNQLKKENER---AQGKMKLLIKSCKQLEEEKE 2810
Query: 343 ELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPA--LLFKARTLLGA 400
L++ S L+ A + ++ + +KET + + A L K +LL +
Sbjct: 2811 ILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLIS 2870
Query: 401 ESHLRNINHQLE 412
L LE
Sbjct: 2871 HEKLEKAKEMLE 2882
Score = 33.9 bits (76), Expect = 0.28
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 17/125 (13%)
Query: 241 EGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLT 300
EG+ T ++++ + + +K E QQR + + + +++Q K+ E T
Sbjct: 10 EGLPTRALQKIQELEGQLDKLKKEKQQR------QFQLDSLEAALQKQKQKVENEKTEGT 63
Query: 301 NLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQL-----------KQLQTKYDELKERKS 349
NLKR+N +++ E + ++ EL E Q+ KQ++ ELK KS
Sbjct: 64 NLKRENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKS 123
Query: 350 SLRNA 354
L +
Sbjct: 124 ELERS 128
Score = 31.2 bits (69), Expect = 1.8
Identities = 57/284 (20%), Positives = 124/284 (43%), Gaps = 46/284 (16%)
Query: 131 KLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAESVTSKKTGPLS 190
K++ + + ES +S+ ++ AE ++ E+++T SS++SE + KT
Sbjct: 1983 KMKEKTQELES-HQSECLHCIQVAEAEVKEKTELLQTL-SSDVSE-----LLKDKTHLQE 2035
Query: 191 AQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKE 250
S+EK++ A+ S +K + + +I+ ++K +K S+ +
Sbjct: 2036 KLQSLEKDSQAL-SLTKCELENQIAQLNKEKELL------------------VKESESLQ 2076
Query: 251 LNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKMI 310
+ ++EK ++ SK +AA+ K +F L +Q + R+
Sbjct: 2077 ARLSESDYEKLNV-------SKALEAALVE-----KGEFALRLSSTQEEVHQLRRG---- 2120
Query: 311 SDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSL-RNAAYFLSNLKQLYQDYS 369
IEK R R+ + + L + +LK+ + + D LK++ +L R N + + D
Sbjct: 2121 --IEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAE 2178
Query: 370 DVQAQEPNVKETYDSSSLPALLFKARTLLGAESHLRNINHQLEK 413
+ +A+ +K + + +F+ L+ S N+ Q+++
Sbjct: 2179 NSKAEVETLKTQIEEMARSLKVFEL-DLVTLRSEKENLTKQIQE 2221
Score = 30.4 bits (67), Expect = 3.1
Identities = 53/235 (22%), Positives = 100/235 (42%), Gaps = 41/235 (17%)
Query: 117 EIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEK 176
E +S+K + R+L+ +S++++ + D E + TQ E+ R+ EL
Sbjct: 2148 ENDSLKDKVENLERELQ-MSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL--- 2203
Query: 177 PAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVH 236
+ VT + EKENL + Q +K+G++S + S K++
Sbjct: 2204 --DLVTLRS----------EKENLTKQIQ---EKQGQLSELDKLLSSFKSL--------- 2239
Query: 237 IWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKES 296
+ ++ I + E KT +E Q + K A+A +Q I E
Sbjct: 2240 --------LEEKEQAEIQIKEESKTAVEMLQN-QLKELNEAVAAL---CGDQEIMKATEQ 2287
Query: 297 QMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSL 351
+ ++ ++ ++ + IEK R R+ + + L + QLK+ + D LK R +L
Sbjct: 2288 SLDPPIEEEH-QLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENL 2341
Score = 29.6 bits (65), Expect = 5.3
Identities = 32/165 (19%), Positives = 73/165 (44%), Gaps = 10/165 (6%)
Query: 262 HLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMI 321
HL Q + +++ + I + ++ +M + L+ + K ++ +K + +
Sbjct: 278 HLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLN 337
Query: 322 EVQDELLRLEPQLKQLQTKYDELKERKSSL--------RNAAYFLSNLKQ-LYQDYSDVQ 372
+ +DEL+R Q Q TKY L+++ L +NA +L+Q + + + Q
Sbjct: 338 KCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQ 397
Query: 373 AQEPNVKETYDSSSLPALLFKARTLLGAESHLRNINHQLEKLLDQ 417
+ + ++ + + KAR L +N+++ L+ LD+
Sbjct: 398 EELSRQQRSFQTLDQECIQMKAR-LTQELQQAKNMHNVLQAELDK 441
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 40.4 bits (93), Expect = 0.003
Identities = 66/293 (22%), Positives = 122/293 (41%), Gaps = 46/293 (15%)
Query: 116 SEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSE 175
S +E + K +K P+S+ E D K S EK T + + I +SE
Sbjct: 1010 SRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYS-EKCVTSKCQEIEIYLKQTISE 1068
Query: 176 KPAESVTSKKTGPLSAQPSVEKENLAIE---SQSKTQKKGKISHDKRKKSRSKAI----- 227
K E +K L + + E++ A+ +Q+ K +I + + S ++AI
Sbjct: 1069 KEVELQHIRKD--LEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLI 1126
Query: 228 --GSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNV 285
+D SD G + +KE ++ P + + +E K+
Sbjct: 1127 TSNTDASD--------GDSVALVKETVVISPPCTGSSEHWKPELEEKILALE------KE 1172
Query: 286 KEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELK 345
KEQ K L+E+ LT+ K + ++K +++ +++EL + + +LQ ++DE
Sbjct: 1173 KEQLQKKLQEA--LTSRK-------AILKKAQEKERHLREELKQQKDDYNRLQEQFDEQS 1223
Query: 346 ERKSSLRNAAYFLSNLKQL-YQDYSDVQAQEPNVKETYDSSSLPAL---LFKA 394
+ ++ + L+QL Q + + P+ + SS P L LFKA
Sbjct: 1224 KENENIGD------QLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKA 1270
Score = 40.0 bits (92), Expect = 0.004
Identities = 60/298 (20%), Positives = 120/298 (40%), Gaps = 35/298 (11%)
Query: 85 EEFSKHCGLSLSSTPPGKEAKRSSDTSGNEAS-EIESVKISAKKPGRKLRPISDD----- 138
EE G L + P +E D S E EIE +K ++ + +
Sbjct: 112 EEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQ 171
Query: 139 SESIEESDTRRKVKSAEKISTQRHEVIRTTASSELS----EKPAESVTSKKTGPLSAQPS 194
+E +S T + K Q E +T ++LS E+ A+ V +K Q
Sbjct: 172 AEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVR 231
Query: 195 VEKENLA-----IESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIK 249
+ ++ L + +++ Q+K ++ K ++ +G + +V + E T+ +
Sbjct: 232 LHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGR--AQVVDLLQQE--LTAAEQ 287
Query: 250 ELNIVLPEFEKTHLEHQ--------QRIESKVCK-------AAIATFYVNVKEQFIKMLK 294
I+ + ++ EH +R ESK+ A + N++E+ +L+
Sbjct: 288 RNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLE 347
Query: 295 ESQMLTNLKRKNAKMISDIEKKRQ-RMIEVQDELLRLEPQLKQLQTKYDELKERKSSL 351
+ + + + S +E+K + M E +L L+ ++LQ+ D LK++ S L
Sbjct: 348 QFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKL 405
Score = 37.0 bits (84), Expect = 0.033
Identities = 57/286 (19%), Positives = 109/286 (38%), Gaps = 53/286 (18%)
Query: 116 SEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTAS----- 170
S ESVK K+ K + E EE + K EK+ R E + +
Sbjct: 2107 SNKESVKSQMKQ---KDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQ 2163
Query: 171 ----------SELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRK 220
+L E +VT S + + I+ K ++K S +
Sbjct: 2164 VTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERK--FSDAIQS 2221
Query: 221 KSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEK--THLEHQQRIESKVCKAAI 278
K + D ++ +++++I + E + + LEH ++I + +
Sbjct: 2222 KEEEIRLKEDNCSVLK---------DQLRQMSIHMEELKINISRLEHDKQIWESKAQTEV 2272
Query: 279 ATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQ 338
+ ++ L+ +N +++S +E+ R Q+EL +LE +LK L+
Sbjct: 2273 QL--------------QQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLK 2318
Query: 339 TKYDELKERKSSLRNAAYFLSNLKQLY-QDYSDVQAQEPNVKETYD 383
D+L + +SL NL+ + Q +D+Q N K +Y+
Sbjct: 2319 ---DQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQ----NSKFSYE 2357
Score = 37.0 bits (84), Expect = 0.033
Identities = 66/320 (20%), Positives = 133/320 (41%), Gaps = 42/320 (13%)
Query: 115 ASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELS 174
+ EIES+K+S + R++ + ++ ++ + KVK E R + +++ ++
Sbjct: 2601 SKEIESLKVSISQLTRQVTALQEEG-TLGLYHAQLKVKEEE---VHRLSALFSSSQKRIA 2656
Query: 175 EKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHD-----KRKKSRSKAIGS 229
E E V +K K+ IE + K + K + HD ++ + +
Sbjct: 2657 ELEEELVCVQK--------EAAKKVGEIEDKLKKELK-HLHHDAGIMRNETETAEERVAE 2707
Query: 230 DTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLE--------HQQRIESKVCKAAIATF 281
D+V + M T + K L + F ++ +++ E K A
Sbjct: 2708 LARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKE 2767
Query: 282 YVNVKEQFI------KMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLK 335
+KEQ + +L E+ N +N+ +S +EK Q+++ ++LL L QL+
Sbjct: 2768 LAQLKEQGLLNRERDALLSETAFSMNSTEENS--LSHLEKLNQQLLSKDEQLLHLSSQLE 2825
Query: 336 QLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPALLFKAR 395
+ + +SL+N L N + ++ +++E + S+ PA + +
Sbjct: 2826 DSYNQVQSFSKAMASLQNERDHLWNELEKFR-----KSEEGKQRSAAQPSTSPA---EVQ 2877
Query: 396 TLLGAESHLRNINHQLEKLL 415
+L A S L+N +L K L
Sbjct: 2878 SLKKAMSSLQNDRDRLLKEL 2897
Score = 36.6 bits (83), Expect = 0.043
Identities = 57/287 (19%), Positives = 120/287 (41%), Gaps = 40/287 (13%)
Query: 136 SDDSESIEESDTRRKVK-SAEKISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQPS 194
S D + E + +RK S ++++ + + + L + A S+ S + LS
Sbjct: 2746 SRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEK 2805
Query: 195 VEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIV 254
+ ++ L+ + Q + +S SKA+ S ++ H+W
Sbjct: 2806 LNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNE-------------- 2851
Query: 255 LPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIE 314
L +F K+ E +QR ++ + ++ LK++ +++L+ +++ +++
Sbjct: 2852 LEKFRKSE-EGKQRSAAQPSTSPAE----------VQSLKKA--MSSLQNDRDRLLKELK 2898
Query: 315 KKRQRMIEVQDELLRLEPQLKQLQTKYDELKE----RKSSLRNAAYFLSNLKQLYQDYSD 370
+Q+ +++ E+ L P QLQ D+ K ++ + + L QL + S
Sbjct: 2899 NLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSS 2958
Query: 371 VQAQEPNVKETYDSSSLPALLFKARTLLGAESHLRNINHQLEKLLDQ 417
+ E +KE Y L A+ K + L SHL+N+ +L Q
Sbjct: 2959 WEIHERRMKEQY----LMAISDKDQQL----SHLQNLIRELRSSSSQ 2997
Score = 33.5 bits (75), Expect = 0.37
Identities = 55/320 (17%), Positives = 126/320 (39%), Gaps = 24/320 (7%)
Query: 103 EAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRH 162
+AK +S E + + + +P + + D S EE K+K + +
Sbjct: 101 KAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELI 160
Query: 163 EVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQ---SKTQKKGKISHDKR 219
++ + +E+PA+S T + + Q EKE Q S+TQ + R
Sbjct: 161 STLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVR 220
Query: 220 KKSR--SKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAA 277
+K + +++ + ++T ++L ++ + E EH++ + +
Sbjct: 221 EKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLE----EHEESLVGRAQVVD 276
Query: 278 IATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQL 337
+ + EQ ++L SQ L ++ ++ + + +E +R+ + ++L + +L
Sbjct: 277 LLQQELTAAEQRNQIL--SQQLQQMEAEHNTLRNTVETERE-----ESKILLEKMEL--- 326
Query: 338 QTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPALLFKARTL 397
E+ ERK S N + +L + ++ QA+ + + + K +
Sbjct: 327 -----EVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHI 381
Query: 398 LGAESHLRNINHQLEKLLDQ 417
L + + + + L DQ
Sbjct: 382 LSLQKTGQELQSACDALKDQ 401
Score = 33.1 bits (74), Expect = 0.48
Identities = 55/288 (19%), Positives = 110/288 (38%), Gaps = 22/288 (7%)
Query: 99 PPGKEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKIS 158
P + + S T G E ++ + +P + D E++ + S +I
Sbjct: 1249 PSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIK 1308
Query: 159 TQRHEVIRTTASSELSEKPAESVTSKKTGPL-SAQPSVEKENLAIESQSKTQKKGKISHD 217
Q E+ EL S +KK+ + Q + K+ L IES + ++ +
Sbjct: 1309 AQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE 1368
Query: 218 ----KRKKSRSKAIGSDTSDIVHIWCPE-----GMKTSDIKELNIVLPEFEKTHLEHQQR 268
K + S+ + G + + E K D+ L+ L E E + Q
Sbjct: 1369 SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTE 1428
Query: 269 I--ESKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDE 326
I + + KA + KE ++ + L +K+K ++ + K+Q ++Q
Sbjct: 1429 IIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAA 1488
Query: 327 LLRLEPQLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQ 374
L+ ++ + LKE KS + +++L + +DV++Q
Sbjct: 1489 LI----------SRKEALKENKSLQEELSLARGTIERLTKSLADVESQ 1526
Score = 32.7 bits (73), Expect = 0.63
Identities = 34/171 (19%), Positives = 76/171 (44%), Gaps = 32/171 (18%)
Query: 190 SAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIK 249
S+ P+VEKE + E QS+T ++ ++ + +K G K
Sbjct: 630 SSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGD-------------------K 670
Query: 250 ELNIVLPEFEKTHLEHQQRIESKVCK------AAIATFYVNVKEQFIKMLKESQMLTNLK 303
L+ V P+ + H + +R++S++ + A + N+ E+ ++ +Q++ K
Sbjct: 671 SLSAV-PDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFK 729
Query: 304 R---KNAKMISDIEKKRQRMIEVQDEL---LRLEPQLKQLQTKYDELKERK 348
+ N+ + + ++R +++ EL L Q+KQL+ E + ++
Sbjct: 730 KNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQR 780
Score = 32.7 bits (73), Expect = 0.63
Identities = 67/310 (21%), Positives = 126/310 (40%), Gaps = 35/310 (11%)
Query: 122 KISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAESV 181
+I K K + IS+ ++ IEE K+A+ S+ T S E + ++
Sbjct: 705 EIYEKNLDEKAKEISNLNQLIEEFK-----KNADNNSSAF-----TALSEERDQLLSQVK 754
Query: 182 TSKKTGPLSAQPSVEKENLA-IESQSKTQKKGKISHDK-----------RKKSRSKAIGS 229
L AQ + NLA E Q + + + +HD KS+ I
Sbjct: 755 ELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEV 814
Query: 230 DTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQF 289
+++ + +++ I+ L L E LE +R+ K + ++ KE
Sbjct: 815 LQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE-- 872
Query: 290 IKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQ----DELLRLEPQLKQLQTKYDELK 345
+++ K Q+L KR + IE+K Q++ E+ +++++L + L + LK
Sbjct: 873 LEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLK 932
Query: 346 ERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPALLFKARTLLGAESHLR 405
E+ + L A K+ ++ ++V + +K+ YD S PA L L+
Sbjct: 933 EQLNLLSRAE---EAKKEQVEEDNEVSS---GLKQNYDEMS-PAGQISKEELQHEFDLLK 985
Query: 406 NINHQLEKLL 415
N Q ++ L
Sbjct: 986 KENEQRKRKL 995
Score = 29.3 bits (64), Expect = 6.9
Identities = 40/210 (19%), Positives = 95/210 (45%), Gaps = 22/210 (10%)
Query: 160 QRHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKR 219
Q+H+ + LS++ E++ ++ + +V+K N +E+ KT KK I +
Sbjct: 2404 QQHDKEIKELENLLSQEEEENIVLEEEN----KKAVDKTNQLMETL-KTIKKENIQQKAQ 2458
Query: 220 KKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIA 279
S K++ S +D I + + + L+I+L EK L + E+ K I
Sbjct: 2459 LDSFVKSMSSLQNDRDRI--VGDYQQLEERHLSIIL---EKDQLIQEAAAENNKLKEEIR 2513
Query: 280 TFYVNVKE----------QFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLR 329
++ + + I+ ++ + +K K + +++ ++ + E++++ +
Sbjct: 2514 GLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNK--ELENKYAK 2571
Query: 330 LEPQLKQLQTKYDELKERKSSLRNAAYFLS 359
LE +LK+ + ++L+ ++L+ LS
Sbjct: 2572 LEEKLKESEEANEDLRRSFNALQEEKQDLS 2601
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,125,788
Number of Sequences: 37866
Number of extensions: 657972
Number of successful extensions: 4887
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 565
Number of HSP's that attempted gapping in prelim test: 3693
Number of HSP's gapped (non-prelim): 1634
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.