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Search of human proteins with 38016156
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38016156 hypothetical protein LOC55345 [Homo sapiens]
(1062 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38016156 hypothetical protein LOC55345 [Homo sapiens] 2129 0.0
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 45 3e-04
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 43 0.001
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 43 0.001
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 43 0.002
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 41 0.005
gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens] 41 0.007
gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens] 41 0.007
gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens] 41 0.007
gi|55770834 centromere protein F [Homo sapiens] 40 0.009
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 40 0.012
gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens] 40 0.015
gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens] 40 0.015
gi|197313732 pleckstrin homology-like domain, family B, member 2... 40 0.015
gi|197313730 pleckstrin homology-like domain, family B, member 2... 40 0.015
gi|197313728 pleckstrin homology-like domain, family B, member 2... 40 0.015
gi|21955172 pleckstrin homology-like domain, family B, member 2 ... 40 0.015
gi|130980075 centromere protein J [Homo sapiens] 39 0.026
gi|60685227 SECIS binding protein 2-like [Homo sapiens] 39 0.026
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 37 0.099
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 37 0.099
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 37 0.099
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 37 0.099
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 37 0.099
gi|56550043 sarcolemma associated protein [Homo sapiens] 37 0.099
gi|169217962 PREDICTED: similar to phosphodiesterase 4D interact... 37 0.13
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 37 0.13
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 37 0.13
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 36 0.17
gi|38044112 restin isoform b [Homo sapiens] 36 0.22
>gi|38016156 hypothetical protein LOC55345 [Homo sapiens]
Length = 1062
Score = 2129 bits (5517), Expect = 0.0
Identities = 1062/1062 (100%), Positives = 1062/1062 (100%)
Query: 1 MESQEFIVLYTHQKMKKSKVWQDGILKITHLGNKAILYDDKGACLESLFLKCLEVKPGDD 60
MESQEFIVLYTHQKMKKSKVWQDGILKITHLGNKAILYDDKGACLESLFLKCLEVKPGDD
Sbjct: 1 MESQEFIVLYTHQKMKKSKVWQDGILKITHLGNKAILYDDKGACLESLFLKCLEVKPGDD 60
Query: 61 LESDRYLITVEEVKVAGAIGIVKQNVNKEAPELNSRTFISSGRSLGCQPSGLKRKFTGFQ 120
LESDRYLITVEEVKVAGAIGIVKQNVNKEAPELNSRTFISSGRSLGCQPSGLKRKFTGFQ
Sbjct: 61 LESDRYLITVEEVKVAGAIGIVKQNVNKEAPELNSRTFISSGRSLGCQPSGLKRKFTGFQ 120
Query: 121 GPRQVPKKMVIMESGESAASHEAKKTGPTIFSPFCSMPPLFPTVGKKDVNNILADPENIV 180
GPRQVPKKMVIMESGESAASHEAKKTGPTIFSPFCSMPPLFPTVGKKDVNNILADPENIV
Sbjct: 121 GPRQVPKKMVIMESGESAASHEAKKTGPTIFSPFCSMPPLFPTVGKKDVNNILADPENIV 180
Query: 181 TYKNRERNAMDFSSVFSPSFQINPEVLCEENYFCSPVNSGNKLSDSLLTNEPVKRDSLAS 240
TYKNRERNAMDFSSVFSPSFQINPEVLCEENYFCSPVNSGNKLSDSLLTNEPVKRDSLAS
Sbjct: 181 TYKNRERNAMDFSSVFSPSFQINPEVLCEENYFCSPVNSGNKLSDSLLTNEPVKRDSLAS 240
Query: 241 HYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTEHFPQKQPQGSLKIATKPKYLIQQE 300
HYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTEHFPQKQPQGSLKIATKPKYLIQQE
Sbjct: 241 HYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTEHFPQKQPQGSLKIATKPKYLIQQE 300
Query: 301 ECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVN 360
ECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVN
Sbjct: 301 ECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVN 360
Query: 361 SNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCS 420
SNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCS
Sbjct: 361 SNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCS 420
Query: 421 SAENDGILSESDIQEDNKIPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLP 480
SAENDGILSESDIQEDNKIPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLP
Sbjct: 421 SAENDGILSESDIQEDNKIPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLP 480
Query: 481 ELKHLQIESSNNSRISDDITDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLNNFETS 540
ELKHLQIESSNNSRISDDITDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLNNFETS
Sbjct: 481 ELKHLQIESSNNSRISDDITDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLNNFETS 540
Query: 541 DTEEESQESNKISQDSESWVKDILVNDGNSCFQKRSENTNCEEIEGEHLPFLTSVSDKPT 600
DTEEESQESNKISQDSESWVKDILVNDGNSCFQKRSENTNCEEIEGEHLPFLTSVSDKPT
Sbjct: 541 DTEEESQESNKISQDSESWVKDILVNDGNSCFQKRSENTNCEEIEGEHLPFLTSVSDKPT 600
Query: 601 VTFPVKETLPSQFCDKTYVGFDMGICKTENTGKEIEEYSDTLSNFESFKWTDAVYGDNKE 660
VTFPVKETLPSQFCDKTYVGFDMGICKTENTGKEIEEYSDTLSNFESFKWTDAVYGDNKE
Sbjct: 601 VTFPVKETLPSQFCDKTYVGFDMGICKTENTGKEIEEYSDTLSNFESFKWTDAVYGDNKE 660
Query: 661 DANKPIQEVRINYDFALPPNKSKGINMNLHIPHIQNQIAENSNLFSEDAQPQPFILGSDL 720
DANKPIQEVRINYDFALPPNKSKGINMNLHIPHIQNQIAENSNLFSEDAQPQPFILGSDL
Sbjct: 661 DANKPIQEVRINYDFALPPNKSKGINMNLHIPHIQNQIAENSNLFSEDAQPQPFILGSDL 720
Query: 721 DKNDEHVLPSTSSSDNSVQLLNTNQNHYECIALDKSNTHISNSLFYPLGKKHLISKDTEA 780
DKNDEHVLPSTSSSDNSVQLLNTNQNHYECIALDKSNTHISNSLFYPLGKKHLISKDTEA
Sbjct: 721 DKNDEHVLPSTSSSDNSVQLLNTNQNHYECIALDKSNTHISNSLFYPLGKKHLISKDTEA 780
Query: 781 HISEPEDLGKIRSPPPDHVEVETAREGKQYWNPRNSSELSGLVNTISILKSLCEHSTALD 840
HISEPEDLGKIRSPPPDHVEVETAREGKQYWNPRNSSELSGLVNTISILKSLCEHSTALD
Sbjct: 781 HISEPEDLGKIRSPPPDHVEVETAREGKQYWNPRNSSELSGLVNTISILKSLCEHSTALD 840
Query: 841 SLEILKKKNTVFQQGTQQTYEPDSPPEVRKPFITVVSPKSPHLHKDSQQILKEDEVELSE 900
SLEILKKKNTVFQQGTQQTYEPDSPPEVRKPFITVVSPKSPHLHKDSQQILKEDEVELSE
Sbjct: 841 SLEILKKKNTVFQQGTQQTYEPDSPPEVRKPFITVVSPKSPHLHKDSQQILKEDEVELSE 900
Query: 901 PLQSVQFSSSGSKEETAFQAVIPKQIERKTCDPKPVEFQGHQVKGSATSGVMVRGHSSQL 960
PLQSVQFSSSGSKEETAFQAVIPKQIERKTCDPKPVEFQGHQVKGSATSGVMVRGHSSQL
Sbjct: 901 PLQSVQFSSSGSKEETAFQAVIPKQIERKTCDPKPVEFQGHQVKGSATSGVMVRGHSSQL 960
Query: 961 GCGQFPDSTEYENFMTETPELPSTCMQIDFLQVTSPEENISTLSPVSTFSLNSRDEDFMV 1020
GCGQFPDSTEYENFMTETPELPSTCMQIDFLQVTSPEENISTLSPVSTFSLNSRDEDFMV
Sbjct: 961 GCGQFPDSTEYENFMTETPELPSTCMQIDFLQVTSPEENISTLSPVSTFSLNSRDEDFMV 1020
Query: 1021 EFSETSLKARTLPDDLHFLNLEGSRYHIALISVYSFKMKFFI 1062
EFSETSLKARTLPDDLHFLNLEGSRYHIALISVYSFKMKFFI
Sbjct: 1021 EFSETSLKARTLPDDLHFLNLEGSRYHIALISVYSFKMKFFI 1062
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 45.4 bits (106), Expect = 3e-04
Identities = 74/374 (19%), Positives = 135/374 (36%), Gaps = 18/374 (4%)
Query: 215 SPVNSGNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEM 274
S S + S+S ++ K DS S+ S S N S + S+SS S + +S
Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679
Query: 275 TEHFPQKQPQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQ 334
+ ++ + ++ S+++ S N+ + S + S
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS----SDSSNSNSSDSDSSNSSDSS 735
Query: 335 SSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNN 394
S S + D +D+ + + +SN D S ++ N S ++
Sbjct: 736 DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS------DSSDSSDSSNSSDSNDSS 789
Query: 395 DPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNKIPFNQNDKGCIKESV- 453
+ S + + S N S S + SS + S+S D+ N +D +S
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849
Query: 454 ---LIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDITDMISESKMDN 510
N + + + S SS ESSN+S SD S+S +
Sbjct: 850 GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909
Query: 511 ESLNSIHESLSNVTQPFLEVTFNLNNFETSDTEEESQESNKISQDSESWVKDIL----VN 566
S +S S S+ + + N N+ ++S++ + S S+ + S D +
Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969
Query: 567 DGNSCFQKRSENTN 580
D NS S N++
Sbjct: 970 DSNSSDSSDSSNSS 983
Score = 37.7 bits (86), Expect = 0.058
Identities = 69/377 (18%), Positives = 135/377 (35%), Gaps = 14/377 (3%)
Query: 218 NSGNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTEH 277
NS + + S +N DS S S S N + S SS S + NS +
Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD 987
Query: 278 FPQKQPQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSP 337
++ + ++ ++ + S N+ + SS SS
Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Query: 338 IHSSTVDGNDTERKPKAQEDDVN--SNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNND 395
S+ N ++ + D + S+ D S + + S ++D
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107
Query: 396 PSWNQEVKLEIPSFNESSSLQVTCSS----AENDGILSESDIQEDNKIPFNQNDKGCIKE 451
S + + S N S S + SS + N S+S D+ + +D +
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD 1167
Query: 452 SVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDITDMISESKMDNE 511
S +++ N+ + + + S+SS +SS++S SD S+S ++
Sbjct: 1168 SSDSSDSSDSSNSSDSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSDS-----SDSSDSSD 1221
Query: 512 SLNSIHESLSNVTQPFLEVTFNLNNFETSDTEEESQESNKISQDSESWVKDILVNDGNSC 571
S +S S SN + + + + ++ +SD+ + S S+ S ++ D GN
Sbjct: 1222 SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDE--SDSQSKSGNGN 1279
Query: 572 FQKRSENTNCEEIEGEH 588
+++ E + H
Sbjct: 1280 NNGSDSDSDSEGSDSNH 1296
Score = 36.6 bits (83), Expect = 0.13
Identities = 72/370 (19%), Positives = 137/370 (37%), Gaps = 31/370 (8%)
Query: 215 SPVNSGNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEM 274
S ++ ++ SDS +++ DS S S S + S + S+SS S +S
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS-------SDSSDSSNSSDSSD 745
Query: 275 TEHFPQKQPQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQ 334
+ ++ + ++ + N N N S + +S
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN----SSDSNDSSNSSDSSDSSNSS 801
Query: 335 SSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNN 394
S S + D +D+ + D +SN D S ++ + D S G++
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSD-SSNSSDSS--------DSSNSSDSSDSSDSSDGSD 852
Query: 395 DPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNKIPFNQNDKGCIKESVL 454
S N+ S N S S + SS +D SD + N+ + + S
Sbjct: 853 SDSSNRS-----DSSNSSDSSDSSDSSNSSDS----SDSSDSNESSNSSDSSDSSNSSDS 903
Query: 455 IKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDI-TDMISESKMDNESL 513
++ + + SESS +SSN+S SD + S+S ++S
Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963
Query: 514 NSIHESLSNVTQPFLEVTFNLNNFETSDTEEESQESNKISQDSESWVKDILVNDGNSCFQ 573
NS S SN + + + + ++ ++SD+ + S S+ + S D + +S
Sbjct: 964 NSSDSSDSN-SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS 1022
Query: 574 KRSENTNCEE 583
S+++N +
Sbjct: 1023 NSSDSSNSSD 1032
Score = 36.6 bits (83), Expect = 0.13
Identities = 72/369 (19%), Positives = 139/369 (37%), Gaps = 24/369 (6%)
Query: 215 SPVNSGNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEM 274
S N + SDS ++ DS S S S + + + SESS+S + NS
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD-----SSESSNSSDNSNSSD 937
Query: 275 TEHFPQKQPQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQ 334
+ + ++ ++ S N S N+ + SS
Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSSNSSD-SSDSNSSDSSDSSNSSDSSDSSDSSDSSD 996
Query: 335 SSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNN 394
SS +S+ D +D+ + +SN D S ++ + S ++
Sbjct: 997 SSDSSNSS-DSSDSSDSSDSSNSSDSSNSSDSS---------NSSDSSDSSDSSDSSDSS 1046
Query: 395 DPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNKIPFNQNDKGCIKESVL 454
D S + + S + S S + SS +D S+S D+ N +D +S
Sbjct: 1047 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS--SDSSESSDSSDSSNSSDSSDSSDSSD 1104
Query: 455 IKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDITDMISESKMDNESLN 514
+++ ++ + + S+SS +SSN+S SD SES ++S +
Sbjct: 1105 SSDSSDSSDSSDSSDSS-NSSDSSDSSDSSDSSDSSNSSDSSDS-----SESSDSSDSSD 1158
Query: 515 SIHESLSNVTQPFLEVTFNLNNFETSDTEEESQESNKISQDSESWVKDILVNDGNSCFQK 574
S S S+ + + + + N+ ++SD+ + S S+ S D + +S
Sbjct: 1159 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1218
Query: 575 RSENTNCEE 583
S++++ +
Sbjct: 1219 SSDSSDSSD 1227
Score = 34.3 bits (77), Expect = 0.64
Identities = 64/353 (18%), Positives = 125/353 (35%), Gaps = 16/353 (4%)
Query: 218 NSGNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTEH 277
+S N S ++ DS S+ S S + S + S+SS S + NS +
Sbjct: 949 DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008
Query: 278 FPQKQPQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSP 337
+ ++ + ++ + + S ++ + + SS SS
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068
Query: 338 IHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNNDPS 397
S+ D +D+ ++ + +SN D S ++ + S ++D S
Sbjct: 1069 SSDSS-DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127
Query: 398 WNQEVKLEIPSFNESSSLQVTCSSAENDGI-------LSESDIQEDNKIPFNQNDKGCIK 450
+ + S N S S + SS +D S+S D+ N +D
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187
Query: 451 ESVLIKENAQEVNTCGTLEK-EYEQSESSLPELKHLQIESSNNSRISDDITDMISESKMD 509
+S +++ ++ + + + S S S++S S D +D S
Sbjct: 1188 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSS 1247
Query: 510 NESLNSIHESLSNVTQPFLEVTFNL-------NNFETSDTEEESQESNKISQD 555
N S +S S+ T + + + NN SD++ E +SN + D
Sbjct: 1248 NSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300
Score = 32.7 bits (73), Expect = 1.9
Identities = 45/180 (25%), Positives = 80/180 (44%), Gaps = 19/180 (10%)
Query: 388 DQSVGNNDP---SWNQEVKLEIPSFNESSSLQVTCSS----AENDGILSESDIQ--EDNK 438
D+S GN+D S N S+N S S AE+D S SD + N
Sbjct: 469 DESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNG 528
Query: 439 IPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDD 498
N ND +S K ++ + ++ + + S+SS + S +NS D
Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSS-DSSDSSDSD------SSDSNSSSDSD 581
Query: 499 ITDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLNNFETSDTEEESQESNKISQDSES 558
+D S D++S +S + S S+ + + + + ++ ++SD++ +S +S S DS+S
Sbjct: 582 SSDSDSSDSSDSDSSDSSNSSDSSDSS---DSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 43.1 bits (100), Expect = 0.001
Identities = 63/271 (23%), Positives = 105/271 (38%), Gaps = 47/271 (17%)
Query: 321 MRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAE 380
+ + SR S S S +D N+T + K+ + NSN +D L + + + ++
Sbjct: 260 LEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTE-NSNSRDTGLSQPRRDSKGDSQ 318
Query: 381 ERKKYNVDQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNKIP 440
E K N+ Q N + + SS + SS EN SES
Sbjct: 319 EDSKENLSQEESQN-----------VDGPSSESSQEANLSSQENS---SES--------- 355
Query: 441 FNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDIT 500
+E V+ + + + ++ E S+SS + H S + SR
Sbjct: 356 ---------QEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESR------ 400
Query: 501 DMISESKMDNESLNSIHESLSNVTQPFLEVTFNLNNFE--TSDTEEESQESNKISQDSES 558
E + D+ES S++ S + P E + + + +S E +S+ES+ DS+S
Sbjct: 401 ----EEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDS 456
Query: 559 WVKDILVNDGNSCFQKRS--ENTNCEEIEGE 587
D NS K S E+ + IE E
Sbjct: 457 QDSSRSKEDSNSTESKSSSEEDGQLKNIEIE 487
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 43.1 bits (100), Expect = 0.001
Identities = 63/271 (23%), Positives = 105/271 (38%), Gaps = 47/271 (17%)
Query: 321 MRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAE 380
+ + SR S S S +D N+T + K+ + NSN +D L + + + ++
Sbjct: 244 LEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTE-NSNSRDTGLSQPRRDSKGDSQ 302
Query: 381 ERKKYNVDQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNKIP 440
E K N+ Q N + + SS + SS EN SES
Sbjct: 303 EDSKENLSQEESQN-----------VDGPSSESSQEANLSSQENS---SES--------- 339
Query: 441 FNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDIT 500
+E V+ + + + ++ E S+SS + H S + SR
Sbjct: 340 ---------QEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESR------ 384
Query: 501 DMISESKMDNESLNSIHESLSNVTQPFLEVTFNLNNFE--TSDTEEESQESNKISQDSES 558
E + D+ES S++ S + P E + + + +S E +S+ES+ DS+S
Sbjct: 385 ----EEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDS 440
Query: 559 WVKDILVNDGNSCFQKRS--ENTNCEEIEGE 587
D NS K S E+ + IE E
Sbjct: 441 QDSSRSKEDSNSTESKSSSEEDGQLKNIEIE 471
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 42.7 bits (99), Expect = 0.002
Identities = 73/347 (21%), Positives = 136/347 (39%), Gaps = 47/347 (13%)
Query: 223 LSDSLLTNEPVKRDSLAS------HYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTE 276
L DSL + VK D L+S + + + K + + +K + + +EL+S E
Sbjct: 928 LKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKE 987
Query: 277 HFPQKQPQGSLK-----IATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMY- 330
K+ SL+ ++ + LIQ AE L Y+ QSE K R +
Sbjct: 988 TQTVKEELESLRSEKDQLSASMRDLIQG---AESYKNLLLEYEKQSEQLDVEKERANNFE 1044
Query: 331 --LSSQSSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAEERKKYNVD 388
+ + + +ST+ + +D+ + ++ L + V+ +R K VD
Sbjct: 1045 HRIEDLTRQLRNSTLQCETIN----SDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVD 1100
Query: 389 QSVGNNDPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNKIPFNQNDKGC 448
+ + Q++K + NE LQV +Q++ K Q K
Sbjct: 1101 KELEAEKLQKEQKIKEHATTVNELEELQV--------------QLQKEKK----QLQK-T 1141
Query: 449 IKESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDITDMISESKM 508
++E L+K++AQ+ +YE+ +K L + +N + +D+ I K
Sbjct: 1142 MQELELVKKDAQQTTLMNMEIADYERL------MKELNQKLTNKNNKIEDLEQEIKIQKQ 1195
Query: 509 DNESLNSIHESLSNVTQPFLEVTFNLNNFETSDTEEESQESNKISQD 555
E+L SL + Q + E + T++E +S + D
Sbjct: 1196 KQETLQEEITSLQSSVQQYEEKNTKIKQLLVK-TKKELADSKQAETD 1241
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 41.2 bits (95), Expect = 0.005
Identities = 112/573 (19%), Positives = 215/573 (37%), Gaps = 97/573 (16%)
Query: 223 LSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEE------------- 269
LSD+ NE ++ SL S N++ K +I L K +S S E+
Sbjct: 394 LSDA--ENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNE 451
Query: 270 ---LNSEMTEHFPQKQPQGSLKIATKPKYLIQQEECAEMKST----ENLYYQHQ--SENT 320
+ S T L++ + K + +E ++ E L Q+Q +++
Sbjct: 452 YEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHM 511
Query: 321 MRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAE 380
+ K + + + S I D ND +++ EDD K+L +Q
Sbjct: 512 ILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQ----------- 560
Query: 381 ERKKYNVDQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNKIP 440
K+ + V ND ++ KLE N L S E++ + + +++ I
Sbjct: 561 --KEKLIQSEVALNDLHLTKQ-KLEDKVENLVDQLN---KSQESNVSIQKENLELKEHIR 614
Query: 441 FNQNDKGCIKESVLIKENA-QEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDI 499
N+ + I+ ++ N N TL KE E E+++L+ S ++++++
Sbjct: 615 QNEEELSRIRNELMQSLNQDSNSNFKDTLLKERE------AEVRNLKQNLSELEQLNENL 668
Query: 500 TDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLNNFETSDTEEESQESNKISQDSESW 559
+ + KM+NE L E + + + L L+ + + E E +I + W
Sbjct: 669 KKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAEL-CW 727
Query: 560 VKDILVNDGNSCFQK--------RSENTNCEEIEGEHLPFLTSVSDKPTVTF-------- 603
K L+ + N ++K R+ NT+ ++E EHL L D
Sbjct: 728 AKKRLLEEANK-YEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMD 786
Query: 604 ----PVKETLPS---------QFCDKTYVGFDMGICKTENTGKEIEEYSDTLSNFESFKW 650
K+ L S Q +K + + ++ +E+++YS L E +
Sbjct: 787 TDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQ 846
Query: 651 T----DAVYGDNKEDAN---KPIQEVRINYDFALPPNKSKGIN-----------MNLHIP 692
T D G KE+ N + ++ +R P K ++ +N
Sbjct: 847 TIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKE 906
Query: 693 HIQNQIAENSNLFSEDAQPQPFILGSDLDKNDE 725
H++ +I + + + Q + +L S ++ E
Sbjct: 907 HLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKE 939
>gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]
Length = 1260
Score = 40.8 bits (94), Expect = 0.007
Identities = 82/401 (20%), Positives = 153/401 (38%), Gaps = 74/401 (18%)
Query: 245 VSQNIR--SKAQILALLKSESSSSCEE-------LNSEMTEHFPQKQPQGSLKIATKPKY 295
+S+NI + QI AL ++ + C+ L ++T +P +Q + + + K
Sbjct: 657 ISENIEVSKELQIPALSTRDNENQCDYRTQNVLGLQKQITNMYPVQQNESKVNKKLRQKV 716
Query: 296 LIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQ 355
+ E +E+ +N E T+++ S ++L+ + I ++ P
Sbjct: 717 NRKTEIISEVNHLDN---DKSIEYTVKSHS---LFLTQKDKEIIPGNLEDPSEFETPALS 770
Query: 356 EDDVNSNLKDLSLQKIIQFVETYAEERKKYNVD-QSVGNNDPSWNQEVKLEIPSFNESSS 414
D + NL D +Q ++ K+ D Q ND ++ +L + +S
Sbjct: 771 TKD-SGNLYDSEIQNVLGV---------KHGHDMQPACQNDSKIGKKPRLNV--CQKSEI 818
Query: 415 LQVTCSSAENDGILSESDIQEDNKIPFNQNDKGCIKES-----------VLIKENAQ--- 460
+ T END D+++DN DK I E+ +LIK+N
Sbjct: 819 IPETNQIYENDN-KGVHDLEKDNFFSLTPKDKETISENLQVTNEFQTVDLLIKDNGNLCD 877
Query: 461 -------EVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDITDMISESKMDNESL 513
E+ T K EQ+ES + +L+ N +I +++ DN+
Sbjct: 878 YDTQNILELKKYVTDRKSAEQNESKINKLR-------NKVNWKTEIISEMNQIYEDNDKD 930
Query: 514 NSIHESLS-------NVTQPFLEV--TFNLNNFETSDTEEESQES--------NKISQDS 556
+ ES + N ++ LE N + E + E+ES + K ++S
Sbjct: 931 AHVQESYTKDLDFKVNKSKQKLECQDIINKHYMEVNSNEKESCDQILDSYKVVKKRKKES 990
Query: 557 ESWVKDILVNDGNSCFQKRSENTNCEEIEGEHLPFLTSVSD 597
K+IL N + +E++ L +TS +D
Sbjct: 991 SCKAKNILTKAKNKLASQLTESSQTSISLESDLKHITSEAD 1031
>gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]
Length = 1265
Score = 40.8 bits (94), Expect = 0.007
Identities = 82/401 (20%), Positives = 153/401 (38%), Gaps = 74/401 (18%)
Query: 245 VSQNIR--SKAQILALLKSESSSSCEE-------LNSEMTEHFPQKQPQGSLKIATKPKY 295
+S+NI + QI AL ++ + C+ L ++T +P +Q + + + K
Sbjct: 657 ISENIEVSKELQIPALSTRDNENQCDYRTQNVLGLQKQITNMYPVQQNESKVNKKLRQKV 716
Query: 296 LIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQ 355
+ E +E+ +N E T+++ S ++L+ + I ++ P
Sbjct: 717 NRKTEIISEVNHLDN---DKSIEYTVKSHS---LFLTQKDKEIIPGNLEDPSEFETPALS 770
Query: 356 EDDVNSNLKDLSLQKIIQFVETYAEERKKYNVD-QSVGNNDPSWNQEVKLEIPSFNESSS 414
D + NL D +Q ++ K+ D Q ND ++ +L + +S
Sbjct: 771 TKD-SGNLYDSEIQNVLGV---------KHGHDMQPACQNDSKIGKKPRLNV--CQKSEI 818
Query: 415 LQVTCSSAENDGILSESDIQEDNKIPFNQNDKGCIKES-----------VLIKENAQ--- 460
+ T END D+++DN DK I E+ +LIK+N
Sbjct: 819 IPETNQIYENDN-KGVHDLEKDNFFSLTPKDKETISENLQVTNEFQTVDLLIKDNGNLCD 877
Query: 461 -------EVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDITDMISESKMDNESL 513
E+ T K EQ+ES + +L+ N +I +++ DN+
Sbjct: 878 YDTQNILELKKYVTDRKSAEQNESKINKLR-------NKVNWKTEIISEMNQIYEDNDKD 930
Query: 514 NSIHESLS-------NVTQPFLEV--TFNLNNFETSDTEEESQES--------NKISQDS 556
+ ES + N ++ LE N + E + E+ES + K ++S
Sbjct: 931 AHVQESYTKDLDFKVNKSKQKLECQDIINKHYMEVNSNEKESCDQILDSYKVVKKRKKES 990
Query: 557 ESWVKDILVNDGNSCFQKRSENTNCEEIEGEHLPFLTSVSD 597
K+IL N + +E++ L +TS +D
Sbjct: 991 SCKAKNILTKAKNKLASQLTESSQTSISLESDLKHITSEAD 1031
>gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]
Length = 1261
Score = 40.8 bits (94), Expect = 0.007
Identities = 82/401 (20%), Positives = 153/401 (38%), Gaps = 74/401 (18%)
Query: 245 VSQNIR--SKAQILALLKSESSSSCEE-------LNSEMTEHFPQKQPQGSLKIATKPKY 295
+S+NI + QI AL ++ + C+ L ++T +P +Q + + + K
Sbjct: 657 ISENIEVSKELQIPALSTRDNENQCDYRTQNVLGLQKQITNMYPVQQNESKVNKKLRQKV 716
Query: 296 LIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQ 355
+ E +E+ +N E T+++ S ++L+ + I ++ P
Sbjct: 717 NRKTEIISEVNHLDN---DKSIEYTVKSHS---LFLTQKDKEIIPGNLEDPSEFETPALS 770
Query: 356 EDDVNSNLKDLSLQKIIQFVETYAEERKKYNVD-QSVGNNDPSWNQEVKLEIPSFNESSS 414
D + NL D +Q ++ K+ D Q ND ++ +L + +S
Sbjct: 771 TKD-SGNLYDSEIQNVLGV---------KHGHDMQPACQNDSKIGKKPRLNV--CQKSEI 818
Query: 415 LQVTCSSAENDGILSESDIQEDNKIPFNQNDKGCIKES-----------VLIKENAQ--- 460
+ T END D+++DN DK I E+ +LIK+N
Sbjct: 819 IPETNQIYENDN-KGVHDLEKDNFFSLTPKDKETISENLQVTNEFQTVDLLIKDNGNLCD 877
Query: 461 -------EVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDITDMISESKMDNESL 513
E+ T K EQ+ES + +L+ N +I +++ DN+
Sbjct: 878 YDTQNILELKKYVTDRKSAEQNESKINKLR-------NKVNWKTEIISEMNQIYEDNDKD 930
Query: 514 NSIHESLS-------NVTQPFLEV--TFNLNNFETSDTEEESQES--------NKISQDS 556
+ ES + N ++ LE N + E + E+ES + K ++S
Sbjct: 931 AHVQESYTKDLDFKVNKSKQKLECQDIINKHYMEVNSNEKESCDQILDSYKVVKKRKKES 990
Query: 557 ESWVKDILVNDGNSCFQKRSENTNCEEIEGEHLPFLTSVSD 597
K+IL N + +E++ L +TS +D
Sbjct: 991 SCKAKNILTKAKNKLASQLTESSQTSISLESDLKHITSEAD 1031
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 40.4 bits (93), Expect = 0.009
Identities = 82/376 (21%), Positives = 139/376 (36%), Gaps = 45/376 (11%)
Query: 232 PVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTEHFPQKQPQG-SLKIA 290
P++RD AS++SG Q + L + K +++SS + NS Q + Q L+
Sbjct: 236 PIRRDFSASYFSG-EQEVTPSRSTLQIGKRDANSSFFD-NSSSPHLLDQLKAQNQELRNK 293
Query: 291 TKPKYLIQQEECAEMKSTENLY--YQHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDT 348
L Q EMK N + Q Q E L+ + +T +
Sbjct: 294 INELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQA 353
Query: 349 ERKPKAQEDDVNSNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNNDPSWNQEVKLEIPS 408
K A E + +DLS Q+ E + +++Q + + + +E+ + S
Sbjct: 354 STKYTALEQKLKKLTEDLSCQR-------QNAESARCSLEQKIKEKEKEFQEELSRQQRS 406
Query: 409 FN--ESSSLQVTCS---------------SAENDGILSESDIQEDNKIPFNQNDKGCIKE 451
F + +Q+ AE D + S E+N F Q K C E
Sbjct: 407 FQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQ--KLCRAE 464
Query: 452 SVL----IKEN-----AQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDITDM 502
IKEN +E+ L K + SE E+ HL+ E N + + +
Sbjct: 465 QAFQASQIKENELRRSMEEMKKENNLLKSH--SEQKAREVCHLEAELKNIKQCLNQSQNF 522
Query: 503 ISESKMDNESLNSIHESL-SNVTQPFLEVTFNLNNFETSDTEEESQESNKISQDSESWVK 561
E K N S ++ L + Q +T +D E++ S + + E ++
Sbjct: 523 AEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIE 582
Query: 562 DILVNDGNSCFQKRSE 577
+ ND S +K S+
Sbjct: 583 QL--NDKLSKTEKESK 596
>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
Length = 681
Score = 40.0 bits (92), Expect = 0.012
Identities = 59/286 (20%), Positives = 117/286 (40%), Gaps = 15/286 (5%)
Query: 423 ENDGILSESDIQE--DNKIPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEY-EQSE-SS 478
E+ +L ES+ QE ++ +DK +++ +EV+ G + E E++E SS
Sbjct: 102 EDISLLPESEEQEREEDGSEIEADDKEDLEDL-----EEEEVSDMGNDDPEMGERAENSS 156
Query: 479 LPELKHLQIESSNNSRISDDITDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLNNFE 538
+L+ + S +S + DI+ + +SK+ N+ E S V F +++ E
Sbjct: 157 KSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKGQGKPREK-SIVDDKFFKLSEMEAYLE 215
Query: 539 TSDTEEESQESNKISQDSESWVKDI-LVNDGNSCFQKRSENTNCEEIEGEHLPFLTSVSD 597
+ EEE ++ N ++ + +DI D F + + ++ F V
Sbjct: 216 NIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFFDPVES 275
Query: 598 KPTVTFPVKETLPSQFCDKTYV---GFDMGICKTENTGKEIEEYSDTLSNFESFKWTDAV 654
+T + L S D ++ I +T+ +++E D + ES K
Sbjct: 276 DEDITNVHDDELDSNKEDDEIAEEEAEELSISETDE-DDDLQENEDNKQHKESLKRVTFA 334
Query: 655 YGDNKEDANKPIQEVRINYDFALPPNKSKGINMNLHIPHIQNQIAE 700
D+ E + + V+ N D + + MN I ++ ++ E
Sbjct: 335 LPDDAETEDTGVLNVKKNSDEVKSSFEKRQEKMNEKIASLEKELLE 380
>gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens]
Length = 1302
Score = 39.7 bits (91), Expect = 0.015
Identities = 101/523 (19%), Positives = 201/523 (38%), Gaps = 101/523 (19%)
Query: 450 KESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDITDMISESKMD 509
+E +I + Q+++ E E E S SLP +++ + ++ D D+ ES
Sbjct: 549 REKYMIGNSVQKIS-----EPEAEISPGSLPVTANMKASENLKHIVNHD--DVFEES--- 598
Query: 510 NESLNSIHE-SLSNVTQPFLEVTFN------LNNFETSDTEEESQESNKISQDSESWVKD 562
E L+S E ++ + P +E + N L+N + DT+E S++++ +S
Sbjct: 599 -EELSSDEEMKMAEMRPPLIETSINQPKVVALSNNKKDDTKETDSLSDEVTHNSNQ---- 653
Query: 563 ILVNDGNSCFQKRSENTNCEEIE--GEHLPFLTSVSDKPTVTFPVKETLPSQFCDKTYVG 620
N+NC + + T S ++ PVK+T ++
Sbjct: 654 --------------NNSNCSSPSRMSDSVSLNTDSSQDTSLCSPVKQT---------HID 690
Query: 621 FDMGICKTENTGKEIEEYSDTL--SNFESFKWTDAVYGDNKEDANKPIQEVRINYDFAL- 677
+ I + + + + D L S E FK D K+D N P ++ + L
Sbjct: 691 INSKIRQEDENFNSLLQNGDILNSSTEEKFKAHD------KKDFNLPEYDLNVEERLVLI 744
Query: 678 -----------PPNKSKGINMNLHIPHIQNQIAENSNL---FSEDAQPQPFILGSD---L 720
+K INMNL N++ N E ++ Q +LG+ +
Sbjct: 745 EKSVDSTATADDTHKLDHINMNL------NKLITNDTFQPEIMERSKTQDIVLGTSFLSI 798
Query: 721 DKNDEHVLPSTSSSDNSVQLLNTNQNHYECIALDKSNTHISNS-LFYPLGKKHLISKDTE 779
+ +E + +++ +N H E + + T +S LG ISK TE
Sbjct: 799 NSKEETEHLENGNKYPNLESVNKVNGHSEETSQSPNRTEPHDSDCSVDLG----ISKSTE 854
Query: 780 AHISEPEDLGKIRSPPPDHVEVETAREGKQYWNPRNSSELSGLVNTISILKSLCEHSTAL 839
P+ G + S H G + ++ + + T+ I ++A+
Sbjct: 855 D--LSPQKSGPVGSVVKSHSITNMEIGGLKIYDILSDNGPQQPSTTVKI-------TSAV 905
Query: 840 DSLEILKKKNT--VFQQ------GTQQTYEPDSPPEVRKPFITVVSPKSPHLHKDSQQIL 891
D I++ K+ ++ Q G+ + + S + F + +P+ P++ +
Sbjct: 906 DGKNIVRSKSATLLYDQPLQVFTGSSSSSDLISGTKAIFKFDSNHNPEEPNIIRGPTSGP 965
Query: 892 KEDEVELSEPLQSVQFSSSGSKEETAFQAVIPKQIERKTCDPK 934
+ P ++Q+SSS + ++T + + QI+ + P+
Sbjct: 966 QSAPQIYGPPQYNIQYSSSAAVKDTLWHSKQNPQIDHASFPPQ 1008
>gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens]
Length = 1371
Score = 39.7 bits (91), Expect = 0.015
Identities = 101/523 (19%), Positives = 201/523 (38%), Gaps = 101/523 (19%)
Query: 450 KESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDITDMISESKMD 509
+E +I + Q+++ E E E S SLP +++ + ++ D D+ ES
Sbjct: 549 REKYMIGNSVQKIS-----EPEAEISPGSLPVTANMKASENLKHIVNHD--DVFEES--- 598
Query: 510 NESLNSIHE-SLSNVTQPFLEVTFN------LNNFETSDTEEESQESNKISQDSESWVKD 562
E L+S E ++ + P +E + N L+N + DT+E S++++ +S
Sbjct: 599 -EELSSDEEMKMAEMRPPLIETSINQPKVVALSNNKKDDTKETDSLSDEVTHNSNQ---- 653
Query: 563 ILVNDGNSCFQKRSENTNCEEIE--GEHLPFLTSVSDKPTVTFPVKETLPSQFCDKTYVG 620
N+NC + + T S ++ PVK+T ++
Sbjct: 654 --------------NNSNCSSPSRMSDSVSLNTDSSQDTSLCSPVKQT---------HID 690
Query: 621 FDMGICKTENTGKEIEEYSDTL--SNFESFKWTDAVYGDNKEDANKPIQEVRINYDFAL- 677
+ I + + + + D L S E FK D K+D N P ++ + L
Sbjct: 691 INSKIRQEDENFNSLLQNGDILNSSTEEKFKAHD------KKDFNLPEYDLNVEERLVLI 744
Query: 678 -----------PPNKSKGINMNLHIPHIQNQIAENSNL---FSEDAQPQPFILGSD---L 720
+K INMNL N++ N E ++ Q +LG+ +
Sbjct: 745 EKSVDSTATADDTHKLDHINMNL------NKLITNDTFQPEIMERSKTQDIVLGTSFLSI 798
Query: 721 DKNDEHVLPSTSSSDNSVQLLNTNQNHYECIALDKSNTHISNS-LFYPLGKKHLISKDTE 779
+ +E + +++ +N H E + + T +S LG ISK TE
Sbjct: 799 NSKEETEHLENGNKYPNLESVNKVNGHSEETSQSPNRTEPHDSDCSVDLG----ISKSTE 854
Query: 780 AHISEPEDLGKIRSPPPDHVEVETAREGKQYWNPRNSSELSGLVNTISILKSLCEHSTAL 839
P+ G + S H G + ++ + + T+ I ++A+
Sbjct: 855 D--LSPQKSGPVGSVVKSHSITNMEIGGLKIYDILSDNGPQQPSTTVKI-------TSAV 905
Query: 840 DSLEILKKKNT--VFQQ------GTQQTYEPDSPPEVRKPFITVVSPKSPHLHKDSQQIL 891
D I++ K+ ++ Q G+ + + S + F + +P+ P++ +
Sbjct: 906 DGKNIVRSKSATLLYDQPLQVFTGSSSSSDLISGTKAIFKFDSNHNPEEPNIIRGPTSGP 965
Query: 892 KEDEVELSEPLQSVQFSSSGSKEETAFQAVIPKQIERKTCDPK 934
+ P ++Q+SSS + ++T + + QI+ + P+
Sbjct: 966 QSAPQIYGPPQYNIQYSSSAAVKDTLWHSKQNPQIDHASFPPQ 1008
>gi|197313732 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 39.7 bits (91), Expect = 0.015
Identities = 87/398 (21%), Positives = 149/398 (37%), Gaps = 48/398 (12%)
Query: 215 SPVNSGNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEM 274
SP+ + + S SL + K+ S Y G +NI K LL + SS S L
Sbjct: 73 SPLGTSVRSSPSLAKIQGSKQFS----YDGTDKNIPMKPPT-PLLNTTSSLSGYPLGRAD 127
Query: 275 TEHFPQKQPQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQ 334
+H+ + + +L+++ KP Y + + KS +N+Y E + S AM+ S
Sbjct: 128 FDHYTGRDSERALRLSEKPPY---SKYSSRHKSHDNVYSLGGLEGRKASGSLLAMWNGSS 184
Query: 335 SSPIHSSTVDGNDTERKPKAQEDDVNSNLKD-LSLQ-KIIQFVETYAE----ERKKYNVD 388
S + + P + + +++D L+LQ K+ + E +E +KY+
Sbjct: 185 LSDAGPPPISRSGAASMPSSPKQARKMSIQDSLALQPKLTRHKELASENINLRTRKYSSS 244
Query: 389 Q-----SVGNNDP-----SWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNK 438
+ + P + NQ L +P N + + T E D L S I DN
Sbjct: 245 SLSHMGAYSRSLPRLYRATENQLTPLSLPPRNSLGNSKRT-KLGEKD--LPHSVIDNDNY 301
Query: 439 IPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDD 498
+ F+ G + E V++ TL S + P + + +S +S SDD
Sbjct: 302 LNFSSLSSGALPYKTSASEGNPYVSS--TL------SVPASPRVARKMLLASTSSCASDD 353
Query: 499 ITDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLN----NFETSDTEEESQES---NK 551
+ N H L+ + N + F+ +D E Q S
Sbjct: 354 F------DQASYVGTNPSHSLLAGESDRVFATRRNFSCGSVEFDEADLESLRQASGTPQP 407
Query: 552 ISQDSESWVKDILVNDGNSCFQKRSENTNCEEIEGEHL 589
++ +S + I D + +R E E E L
Sbjct: 408 ALRERKSSISSISGRDDLMDYHRRQREERLREQEMERL 445
>gi|197313730 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 39.7 bits (91), Expect = 0.015
Identities = 87/398 (21%), Positives = 149/398 (37%), Gaps = 48/398 (12%)
Query: 215 SPVNSGNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEM 274
SP+ + + S SL + K+ S Y G +NI K LL + SS S L
Sbjct: 73 SPLGTSVRSSPSLAKIQGSKQFS----YDGTDKNIPMKPPT-PLLNTTSSLSGYPLGRAD 127
Query: 275 TEHFPQKQPQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQ 334
+H+ + + +L+++ KP Y + + KS +N+Y E + S AM+ S
Sbjct: 128 FDHYTGRDSERALRLSEKPPY---SKYSSRHKSHDNVYSLGGLEGRKASGSLLAMWNGSS 184
Query: 335 SSPIHSSTVDGNDTERKPKAQEDDVNSNLKD-LSLQ-KIIQFVETYAE----ERKKYNVD 388
S + + P + + +++D L+LQ K+ + E +E +KY+
Sbjct: 185 LSDAGPPPISRSGAASMPSSPKQARKMSIQDSLALQPKLTRHKELASENINLRTRKYSSS 244
Query: 389 Q-----SVGNNDP-----SWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNK 438
+ + P + NQ L +P N + + T E D L S I DN
Sbjct: 245 SLSHMGAYSRSLPRLYRATENQLTPLSLPPRNSLGNSKRT-KLGEKD--LPHSVIDNDNY 301
Query: 439 IPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDD 498
+ F+ G + E V++ TL S + P + + +S +S SDD
Sbjct: 302 LNFSSLSSGALPYKTSASEGNPYVSS--TL------SVPASPRVARKMLLASTSSCASDD 353
Query: 499 ITDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLN----NFETSDTEEESQES---NK 551
+ N H L+ + N + F+ +D E Q S
Sbjct: 354 F------DQASYVGTNPSHSLLAGESDRVFATRRNFSCGSVEFDEADLESLRQASGTPQP 407
Query: 552 ISQDSESWVKDILVNDGNSCFQKRSENTNCEEIEGEHL 589
++ +S + I D + +R E E E L
Sbjct: 408 ALRERKSSISSISGRDDLMDYHRRQREERLREQEMERL 445
>gi|197313728 pleckstrin homology-like domain, family B, member 2
isoform b [Homo sapiens]
Length = 1237
Score = 39.7 bits (91), Expect = 0.015
Identities = 87/398 (21%), Positives = 149/398 (37%), Gaps = 48/398 (12%)
Query: 215 SPVNSGNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEM 274
SP+ + + S SL + K+ S Y G +NI K LL + SS S L
Sbjct: 100 SPLGTSVRSSPSLAKIQGSKQFS----YDGTDKNIPMKPPT-PLLNTTSSLSGYPLGRAD 154
Query: 275 TEHFPQKQPQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQ 334
+H+ + + +L+++ KP Y + + KS +N+Y E + S AM+ S
Sbjct: 155 FDHYTGRDSERALRLSEKPPY---SKYSSRHKSHDNVYSLGGLEGRKASGSLLAMWNGSS 211
Query: 335 SSPIHSSTVDGNDTERKPKAQEDDVNSNLKD-LSLQ-KIIQFVETYAE----ERKKYNVD 388
S + + P + + +++D L+LQ K+ + E +E +KY+
Sbjct: 212 LSDAGPPPISRSGAASMPSSPKQARKMSIQDSLALQPKLTRHKELASENINLRTRKYSSS 271
Query: 389 Q-----SVGNNDP-----SWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNK 438
+ + P + NQ L +P N + + T E D L S I DN
Sbjct: 272 SLSHMGAYSRSLPRLYRATENQLTPLSLPPRNSLGNSKRT-KLGEKD--LPHSVIDNDNY 328
Query: 439 IPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDD 498
+ F+ G + E V++ TL S + P + + +S +S SDD
Sbjct: 329 LNFSSLSSGALPYKTSASEGNPYVSS--TL------SVPASPRVARKMLLASTSSCASDD 380
Query: 499 ITDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLN----NFETSDTEEESQES---NK 551
+ N H L+ + N + F+ +D E Q S
Sbjct: 381 F------DQASYVGTNPSHSLLAGESDRVFATRRNFSCGSVEFDEADLESLRQASGTPQP 434
Query: 552 ISQDSESWVKDILVNDGNSCFQKRSENTNCEEIEGEHL 589
++ +S + I D + +R E E E L
Sbjct: 435 ALRERKSSISSISGRDDLMDYHRRQREERLREQEMERL 472
>gi|21955172 pleckstrin homology-like domain, family B, member 2
isoform c [Homo sapiens]
Length = 1210
Score = 39.7 bits (91), Expect = 0.015
Identities = 87/398 (21%), Positives = 149/398 (37%), Gaps = 48/398 (12%)
Query: 215 SPVNSGNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEM 274
SP+ + + S SL + K+ S Y G +NI K LL + SS S L
Sbjct: 73 SPLGTSVRSSPSLAKIQGSKQFS----YDGTDKNIPMKPPT-PLLNTTSSLSGYPLGRAD 127
Query: 275 TEHFPQKQPQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQ 334
+H+ + + +L+++ KP Y + + KS +N+Y E + S AM+ S
Sbjct: 128 FDHYTGRDSERALRLSEKPPY---SKYSSRHKSHDNVYSLGGLEGRKASGSLLAMWNGSS 184
Query: 335 SSPIHSSTVDGNDTERKPKAQEDDVNSNLKD-LSLQ-KIIQFVETYAE----ERKKYNVD 388
S + + P + + +++D L+LQ K+ + E +E +KY+
Sbjct: 185 LSDAGPPPISRSGAASMPSSPKQARKMSIQDSLALQPKLTRHKELASENINLRTRKYSSS 244
Query: 389 Q-----SVGNNDP-----SWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNK 438
+ + P + NQ L +P N + + T E D L S I DN
Sbjct: 245 SLSHMGAYSRSLPRLYRATENQLTPLSLPPRNSLGNSKRT-KLGEKD--LPHSVIDNDNY 301
Query: 439 IPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDD 498
+ F+ G + E V++ TL S + P + + +S +S SDD
Sbjct: 302 LNFSSLSSGALPYKTSASEGNPYVSS--TL------SVPASPRVARKMLLASTSSCASDD 353
Query: 499 ITDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLN----NFETSDTEEESQES---NK 551
+ N H L+ + N + F+ +D E Q S
Sbjct: 354 F------DQASYVGTNPSHSLLAGESDRVFATRRNFSCGSVEFDEADLESLRQASGTPQP 407
Query: 552 ISQDSESWVKDILVNDGNSCFQKRSENTNCEEIEGEHL 589
++ +S + I D + +R E E E L
Sbjct: 408 ALRERKSSISSISGRDDLMDYHRRQREERLREQEMERL 445
>gi|130980075 centromere protein J [Homo sapiens]
Length = 1338
Score = 38.9 bits (89), Expect = 0.026
Identities = 63/295 (21%), Positives = 121/295 (41%), Gaps = 31/295 (10%)
Query: 243 SGVSQNIRSKAQILALLKSESSSSCEELNSEMTEHFPQKQPQGSLKIATKPKYLIQQEEC 302
+G + + +K+ I +K ES SS + + E + +++ + +L++ ++L ++
Sbjct: 530 TGPASRLAAKSPIRETMK-ESESSLDVSLQKKLETWEREKEKENLEL---DEFLFLEQAA 585
Query: 303 AEMKSTEN-------LYYQHQSENTMRNKSRWAMYLSSQSSPIH--SSTVDGNDTERKPK 353
E+ + N L Q R S + +++P S D + +
Sbjct: 586 DEISFSSNSSFVLKILERDQQICKGHRMSSTPVKAVPQKTNPADPISHCNRSEDLDHTAR 645
Query: 354 AQEDDVNSNLKDL-SLQKIIQFVETYAEERKKYNVDQSVGNNDPSWNQEVKLEIPSFNES 412
+E + K L SL + E + RK V +S N WN +P+ + S
Sbjct: 646 EKESECEVAPKQLHSLSSADELREQPCKIRKA--VQKSTSENQTEWNARDDEGVPNSDSS 703
Query: 413 SS----LQVTCSSAENDGILSESDIQEDNKIPFNQNDKGCIKESVLIKENAQEVNTCGTL 468
+ L VT + D E I P +DKG K++ ++ ++V+
Sbjct: 704 TDSEEQLDVTIKPSTED---RERGISSREDSPQVCDDKGPFKDTRTQEDKRRDVDL-DLS 759
Query: 469 EKEYEQSESSLPELKHLQIESSNNSRISDDITDMISESKMDNE-SLNSIHESLSN 522
+K+Y ES + +KH E S +S +S +S+ D+E + + E+L N
Sbjct: 760 DKDYSSDESIMESIKHKVSEPSRSSSLS------LSKMDFDDERTWTDLEENLCN 808
>gi|60685227 SECIS binding protein 2-like [Homo sapiens]
Length = 1056
Score = 38.9 bits (89), Expect = 0.026
Identities = 60/289 (20%), Positives = 122/289 (42%), Gaps = 38/289 (13%)
Query: 314 QHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQ 373
Q Q+E ++N + ++ +P +S + +P ++ ++ ++ +
Sbjct: 782 QEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETSD 841
Query: 374 FVETYAEERKKYNVDQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCS--SAENDGILSES 431
+E +E K+ + S PS ++ + P + SL T S SA + G + S
Sbjct: 842 GLEA-SENEKEVSCKHSTSEK-PS---KLPFDTPPIGKQPSLVATGSTTSATSAGKSTAS 896
Query: 432 DIQE----DNKIPFNQN-DKGCIKESVLIKENAQEVNTCGTL-----EKEYEQSESSLPE 481
D +E D + Q+ + G + S N+ +T TL E+E ++ E +
Sbjct: 897 DKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEED 956
Query: 482 LKH--LQIESSNNSRISDDITDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLNNFET 539
H + +E NSRI +SE++ E+L + ++L+ + +E ++
Sbjct: 957 YTHEPISVEVQLNSRIES----WVSETQRTMETLQ-LGKTLNGSEEDNVE--------QS 1003
Query: 540 SDTEEESQESNKISQDSESWVKDILVNDGNSCFQKRSENTNCEEIEGEH 588
+ E E+ E + DSE+W D + G + +++NC + EH
Sbjct: 1004 GEEEAEAPEVLEPGMDSEAWTADQQASPG------QQKSSNCSSLNKEH 1046
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 37.0 bits (84), Expect = 0.099
Identities = 41/179 (22%), Positives = 77/179 (43%), Gaps = 24/179 (13%)
Query: 335 SSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNN 394
S P +G+ R K +E + +K ++I++ E + + QS G++
Sbjct: 162 SFPREGQKEEGSQQNRDMKDEEKEQQLTMKP---EEIVRLREELSHINQSLLQSQSSGDS 218
Query: 395 D-------PSWNQEVKL----EIPSFNES-SSLQVTCSSAENDGILSES---DIQEDNKI 439
PS +++K E+ +++ LQ+ C+SAEN+ D+++ N +
Sbjct: 219 SDDSGAQHPSSGEKLKYNQQGEVQQLHQNLHRLQILCNSAENELRYERGQNLDLKQHNSL 278
Query: 440 PFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLPE-----LKHLQ-IESSNN 492
+N K I+ ++ C +L EY+ + + E LKH Q I+S NN
Sbjct: 279 LQEENIKIKIELKHAQQKLLDSTKMCSSLTAEYKHCQQKIKELELEVLKHTQSIKSQNN 337
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 37.0 bits (84), Expect = 0.099
Identities = 54/287 (18%), Positives = 117/287 (40%), Gaps = 22/287 (7%)
Query: 297 IQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQE 356
I+QE + +L Q Q NT++ + ++ + + N RK +
Sbjct: 796 IEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDA 855
Query: 357 DDVNSNLKDL--SLQKIIQFVETYAEERKKYNVDQS-VGNNDPSWNQEVKLEIPSFNESS 413
D L+D + Q +T E K+ +++ +G QE++ E S ++
Sbjct: 856 DGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSL--AA 913
Query: 414 SLQVTCSSAENDGILSESDIQEDNKIPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYE 473
L++T + A+++ L+ S +E ++ +K I + + IKE ++E
Sbjct: 914 QLEITLTKADSEQ-LARSIAEEQ----YSDLEKEKIMKELEIKE------MMARHKQELT 962
Query: 474 QSESSLPELKHLQIESSNNSRISDDITDMISESKMDNESLNSIHESLSNVTQPFLEVTFN 533
+ ++++ L+ N ++ D+ ++ +E + N L + E LS + +
Sbjct: 963 EKDATIASLEE------TNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAI 1016
Query: 534 LNNFETSDTEEESQESNKISQDSESWVKDILVNDGNSCFQKRSENTN 580
FE E + ++ +++ +E + V GN +R E N
Sbjct: 1017 KAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKEN 1063
Score = 34.3 bits (77), Expect = 0.64
Identities = 81/377 (21%), Positives = 136/377 (36%), Gaps = 63/377 (16%)
Query: 227 LLTNEPVKR--DSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEMT--EHFPQKQ 282
LL++ P R DS+ S + SQ I+ K L E L++EM E QK
Sbjct: 421 LLSDSPSCRETDSIQSRKNEESQEIQKKLYTLE----------EHLSNEMQAKEELEQKC 470
Query: 283 PQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSST 342
+ ++ K L +EE KS E+ Q + E + A Y Q H +
Sbjct: 471 KSVNTRLEKTAKEL--EEEITLRKSVESALRQLEREKALLQHKN-AEY---QRKADHEAD 524
Query: 343 VDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNNDPSWNQEV 402
K + E+DVNS LKD E+ KK N + + + Q
Sbjct: 525 --------KKRNLENDVNS-LKD------------QLEDLKKRNQNSQISTEKVNQLQRQ 563
Query: 403 KLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNKIPFNQNDKGCIKESVLIKENAQEV 462
E + + S T + S IQ+ + DK C+ E+ +K + +
Sbjct: 564 LDETNALLRTES--DTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFI 621
Query: 463 NTCGTLEKEYEQSESSLPELKHLQ------IESSNNSRISDDITDMISESKMDNESLNSI 516
N LE E + LQ E N +I + + E + E +
Sbjct: 622 NLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKIL--LAKVELEKRQLQERFTDL 679
Query: 517 HESLSNVTQPFLEVTFNLNNFETSDTEEESQ---------ESNKISQDSESWVKDILVND 567
+ SN+ +++T+ L + S +EE++ + NKI + E + +
Sbjct: 680 EKEKSNME---IDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEM 736
Query: 568 GNSCFQKRSENTNCEEI 584
++R+ E +
Sbjct: 737 EKKLLEERTLKQKVENL 753
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
sapiens]
Length = 2346
Score = 37.0 bits (84), Expect = 0.099
Identities = 73/377 (19%), Positives = 147/377 (38%), Gaps = 68/377 (18%)
Query: 220 GNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTEHFP 279
G + ++++T E + SL + + + +++ I+ LLK + S +E NS++T
Sbjct: 1080 GEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIINLLKEQLVLSSKEGNSKLT---- 1135
Query: 280 QKQPQGSLKIATKPKYLIQQEECAEMKSTENL----YYQHQSEN--TMRNKSRWAMYLSS 333
P+ L+ E +TE + +QHQ E T+R R
Sbjct: 1136 -------------PELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVRPFPRPQSLDLG 1182
Query: 334 QSSPIHSSTVDGNDTERKP---------------KAQEDDVNSNLKDLSLQKIIQFVETY 378
+ + + +D R P ++Q +DL + ++ +
Sbjct: 1183 ATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVF 1242
Query: 379 AE--ERKKYNVDQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQED 436
A+ E +KY V + + ++++++++ TC +EN+ E+ E
Sbjct: 1243 AQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYE-----TCGRSENEAEREETTSPE- 1296
Query: 437 NKIPFNQNDKGCIKESVLIKENAQEVNTCGTL---EKEYEQSESSLPELKHLQI--ESSN 491
+ +KE VL++ E G+ E + E+ L + + ++ +S N
Sbjct: 1297 ------CEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSEN 1350
Query: 492 NSRISDDITDMISESKMDN---ESLNSIHESLSNVTQPF---LEVTFNLNNFETSDTEEE 545
+ DI D+ ++ + N ++L S SLS VT + LE + L T E
Sbjct: 1351 ILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLS-VTSDYSSSLERPWKLRAVGTL----E 1405
Query: 546 SQESNKISQDSESWVKD 562
+ + + E W+ D
Sbjct: 1406 GSSPHSVPDEDEGWLSD 1422
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 37.0 bits (84), Expect = 0.099
Identities = 86/418 (20%), Positives = 164/418 (39%), Gaps = 74/418 (17%)
Query: 353 KAQEDDVN-SNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNNDPSWNQEVKLEIPSFNE 411
+AQ ++ N +KDL QK Q A+ + KY+ ++S+ E
Sbjct: 146 EAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSL------------------RE 187
Query: 412 SSSLQVTCSSAENDGILSESDIQEDNKIPFNQNDKGCIKESVLIKENAQEVNTC---GTL 468
++ +VT + E + E+ + +D K Q + I++ ++K+ +V T TL
Sbjct: 188 AAEQKVTRLTEE---LNKEATVIQDLKTELLQ--RPGIEDVAVLKKELVQVQTLMDNMTL 242
Query: 469 EKEYEQSESSLPELKHLQIESSNN----SRISDDITDMISESKMDNESLNSIHESLSNVT 524
E+E E SE E K LQ + +++ S++ ++ E + + L + S++ +T
Sbjct: 243 ERERE-SEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELT 301
Query: 525 QPFLEVTFNLNNFETSDTEEESQESNKISQDSESWVKDILVNDGNSCFQKRSENTNCEEI 584
Q +T NL E T+ E + + + V+ N ++ +C+++
Sbjct: 302 QKNQTLTENLLKKEQDYTKLEEKHNEE------------SVSKKNIQATLHQKDLDCQQL 349
Query: 585 EGEHLPFLTSVSDKPTVTFPVKETLPSQFCDKTYVGFDMGICKTENTGKEIEEYSDTLSN 644
+ + +S T + L K E T K EE S+ +
Sbjct: 350 Q-------SRLSASETSLHRIHVELSE---------------KGEATQKLKEELSEVETK 387
Query: 645 FESFKWTDAVYGDNKEDANKPIQEVRINYDFALPPNKSKGINMNLHIPHIQNQIAENSNL 704
++ K +E+ ++ + + SK + + ++ E L
Sbjct: 388 YQHLKAEFKQLQQQREEK----EQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQL 443
Query: 705 FSE---DAQPQPFILGSDLDKNDEHVLPS-TSSSDNSVQLLNTNQNHYECIALDKSNT 758
SE D + Q L L + +E + T+S++ QL T Q H E AL +S T
Sbjct: 444 SSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTT 501
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 37.0 bits (84), Expect = 0.099
Identities = 82/410 (20%), Positives = 158/410 (38%), Gaps = 78/410 (19%)
Query: 222 KLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQI---LALLKSESSSSCEELNSEMTEHF 278
++++ L VK+ L S S +S+ ++++ ++ L++LK ++ +EL ++M E
Sbjct: 670 EMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQK 729
Query: 279 PQKQPQGSLKIATKPKYLIQQEECAE----------MKSTENLYYQHQS--ENTMRNKSR 326
Q Q I + + IQ+ E A +K + +HQ+ EN + R
Sbjct: 730 NHHQQQVD-SIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKR 788
Query: 327 WAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDV---NSNLKDLSLQKII---QFVETYAE 380
L S+ + + T + KA E+ + L DL ++I+ Q E A+
Sbjct: 789 SEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQ 848
Query: 381 ----------------------ERKKYNVDQSVGN---------NDPSWNQEVKLEIPSF 409
E++ ++Q V + D + QE +I
Sbjct: 849 KKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVE 908
Query: 410 NESSSLQVTCSSAENDGILSESDIQEDNKI-----PFNQNDKGCIKESVLIKENAQEVNT 464
E+ LQ+ + IL++ +++ I + K K+ +K+ A+E+
Sbjct: 909 KENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQE 968
Query: 465 C---------GTLEKEYEQSESSLPE------LKHLQIESSNNSRISDDITDMISESKMD 509
L+KE E + L + K L++ +N++ ISD ++ + + K
Sbjct: 969 TLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQ 1028
Query: 510 NESLNSIHESLSNVTQPFLEVTFN-----LNNFETSDTEEESQESNKISQ 554
ESL +H N E N L +E+ QE ++ Q
Sbjct: 1029 IESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQ 1078
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 37.0 bits (84), Expect = 0.099
Identities = 81/390 (20%), Positives = 153/390 (39%), Gaps = 83/390 (21%)
Query: 191 DFSSVFSPSFQINPEVLCEENYFCSPVNSGNKLSDSLLTNEPVKRDSLASH-YSGVSQNI 249
DFS SPS + + + ++ + D NEP+ + SL G I
Sbjct: 429 DFSDTLSPSKEKSSD------------DTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEI 476
Query: 250 RSKAQILALLKS---------ESSSSCEELNSEMTEHFPQKQPQGSLKIATKPKYLIQQE 300
+K +I L K S C EL + + E +K + ++ +TK ++Q +
Sbjct: 477 EAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEE--RKAYRNQVEESTKQIQVLQAQ 534
Query: 301 ECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVN 360
TENL + SE T + + +H + K ++ D
Sbjct: 535 LQRLHIDTENLREEKDSEITSTRDE--LLSARDEILLLHQAAA-------KVASERDTDI 585
Query: 361 SNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNN----------DPSWNQEVKL--EIPS 408
++L++ L+K+ +E + + +Y + + N D + +L E+
Sbjct: 586 ASLQE-ELKKVRAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEK 644
Query: 409 FN-ESSSLQVTCSSAENDGILSESDIQEDNKIPFN----------------------QND 445
E ++L+ C S + + +L S++Q K N +N
Sbjct: 645 LRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQ 704
Query: 446 KGCIKESVLIKENA-------QEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDD 498
G +KE L +++A + N ++KEYE++++ L ELK L+ E + + S
Sbjct: 705 VGSLKEQHL-RDSADLKTLLSKAENQAKDVQKEYEKTQTVLSELK-LKFEMTEQEKQS-- 760
Query: 499 ITDMISESKMDNESLNSIHESLSNVTQPFL 528
ITD + + K +L + E +N P++
Sbjct: 761 ITDELKQCK---NNLKLLREKGNNKPWPWM 787
>gi|169217962 PREDICTED: similar to phosphodiesterase 4D interacting
protein [Homo sapiens]
Length = 424
Score = 36.6 bits (83), Expect = 0.13
Identities = 71/374 (18%), Positives = 144/374 (38%), Gaps = 62/374 (16%)
Query: 220 GNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTEHFP 279
G + ++++T E + SL + + + +++ I+ LLK + S +E NS++T
Sbjct: 32 GEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIINLLKEQLVLSSKEGNSKLT---- 87
Query: 280 QKQPQGSLKIATKPKYLIQQEECAEMKSTENL----YYQHQSEN--TMRNKSRWAMYLSS 333
P+ L+ E +TE + +QHQ E T+R R
Sbjct: 88 -------------PELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVRPFPRPQSLDLG 134
Query: 334 QSSPIHSSTVDGNDTERKP---------------KAQEDDVNSNLKDLSLQKIIQFVETY 378
+ + + +D R P ++Q +DL + ++ +
Sbjct: 135 ATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVF 194
Query: 379 AE--ERKKYNVDQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQED 436
A+ E +KY V + + ++++++++ TC +EN+ E+ E
Sbjct: 195 AQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYE-----TCGRSENEAEREETTSPE- 248
Query: 437 NKIPFNQNDKGCIKESVLIKENAQEVNTCGTL---EKEYEQSESSLPELKHLQI--ESSN 491
+ +KE VL++ E G+ E + E+ L + + ++ +S N
Sbjct: 249 ------CEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSEN 302
Query: 492 NSRISDDITDMISESKMDN---ESLNSIHESLSNVTQPFLEVTFNLNNFETSDTEEESQE 548
+ DI D+ ++ + N ++L S SLS VT + T E S
Sbjct: 303 ILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLS-VTSDYSSSLERPRKLRAVGTLEGS-S 360
Query: 549 SNKISQDSESWVKD 562
+ + + E W+ D
Sbjct: 361 PHSVPDEDEGWLSD 374
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 36.6 bits (83), Expect = 0.13
Identities = 85/385 (22%), Positives = 147/385 (38%), Gaps = 67/385 (17%)
Query: 225 DSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTEHFPQKQPQ 284
D LL E + LA + I K ++ L SE EE ++ E K P+
Sbjct: 2036 DKLLPTEDQSFNDLAHDVIHWIKEI--KESLMVLNSSEGKMPLEERIQKIKEIILLK-PE 2092
Query: 285 GSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSSTVD 344
G +I T K E K+ ++ +Q +NT+ S YLS Q + ++
Sbjct: 2093 GDARIETIMKQAESSEAPLVQKTLTDI--SNQWDNTLHLAST---YLSHQEKLL----LE 2143
Query: 345 GNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAEERKKYNVD---------------- 388
G K ++D+ L +L ++ F + + KK +
Sbjct: 2144 GE----KYLQSKEDLRLMLIELKKKQEAGFALQHGLQEKKAQLKIYKKFLKKAQDLTSLL 2199
Query: 389 ---QSVGN------NDPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNKI 439
+S GN +PS+++E LEI +ES Q+ S DG + E D +
Sbjct: 2200 KELKSQGNYLLECTKNPSFSEEPWLEIKHLHESLLQQLQDSVQNLDGHVREHDSYQVCVT 2259
Query: 440 PFNQNDKGCIKE----------SVLIKENAQEVNTC--------GTLE------KEYEQS 475
N KE + ++E Q++ GTL+ K +Q+
Sbjct: 2260 DLNTTLDNFSKEFVSFSDKPVDQIAVEEKLQKLQELENRLSLQDGTLKKILALAKSVKQN 2319
Query: 476 ESSLPELKHLQIESSNNSRISDDITDMISESKMDNE-SLNSIHESLSNVTQPFLEVTFNL 534
SS+ + K ++ + + D+ + ++ +K + E LNSI +S + +
Sbjct: 2320 TSSVGQ-KIIKDDIKSLQCKQKDLENRLASAKQEMECCLNSILKSKRSTEKKGKFTLPGR 2378
Query: 535 NNFETSDTEEESQESNKISQDSESW 559
TSD +E +QES + + E W
Sbjct: 2379 EKQATSDVQESTQESAAVEKLEEDW 2403
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 36.6 bits (83), Expect = 0.13
Identities = 85/385 (22%), Positives = 147/385 (38%), Gaps = 67/385 (17%)
Query: 225 DSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTEHFPQKQPQ 284
D LL E + LA + I K ++ L SE EE ++ E K P+
Sbjct: 2036 DKLLPTEDQSFNDLAHDVIHWIKEI--KESLMVLNSSEGKMPLEERIQKIKEIILLK-PE 2092
Query: 285 GSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSSTVD 344
G +I T K E K+ ++ +Q +NT+ S YLS Q + ++
Sbjct: 2093 GDARIETIMKQAESSEAPLVQKTLTDI--SNQWDNTLHLAST---YLSHQEKLL----LE 2143
Query: 345 GNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAEERKKYNVD---------------- 388
G K ++D+ L +L ++ F + + KK +
Sbjct: 2144 GE----KYLQSKEDLRLMLIELKKKQEAGFALQHGLQEKKAQLKIYKKFLKKAQDLTSLL 2199
Query: 389 ---QSVGN------NDPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNKI 439
+S GN +PS+++E LEI +ES Q+ S DG + E D +
Sbjct: 2200 KELKSQGNYLLECTKNPSFSEEPWLEIKHLHESLLQQLQDSVQNLDGHVREHDSYQVCVT 2259
Query: 440 PFNQNDKGCIKE----------SVLIKENAQEVNTC--------GTLE------KEYEQS 475
N KE + ++E Q++ GTL+ K +Q+
Sbjct: 2260 DLNTTLDNFSKEFVSFSDKPVDQIAVEEKLQKLQELENRLSLQDGTLKKILALAKSVKQN 2319
Query: 476 ESSLPELKHLQIESSNNSRISDDITDMISESKMDNE-SLNSIHESLSNVTQPFLEVTFNL 534
SS+ + K ++ + + D+ + ++ +K + E LNSI +S + +
Sbjct: 2320 TSSVGQ-KIIKDDIKSLQCKQKDLENRLASAKQEMECCLNSILKSKRSTEKKGKFTLPGR 2378
Query: 535 NNFETSDTEEESQESNKISQDSESW 559
TSD +E +QES + + E W
Sbjct: 2379 EKQATSDVQESTQESAAVEKLEEDW 2403
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 36.2 bits (82), Expect = 0.17
Identities = 103/522 (19%), Positives = 215/522 (41%), Gaps = 63/522 (12%)
Query: 269 ELNSEMTEHFPQKQPQGSLKIATKPKYL------IQQEECAEMKSTENLYYQHQSEN-TM 321
EL S + E K+ + ++ K + + ++Q+ E+K ENL Q + EN +
Sbjct: 2368 ELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVL 2427
Query: 322 RNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAEE 381
+++ A+ ++Q + N + KAQ D ++ L + + V Y +
Sbjct: 2428 EEENKKAVDKTNQLMETLKTIKKENIQQ---KAQLDSFVKSMSSLQNDR-DRIVGDYQQL 2483
Query: 382 RKKY-----NVDQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQED 436
+++ DQ + + N ++K EI S + +A+ D L + +
Sbjct: 2484 EERHLSIILEKDQLI-QEAAAENNKLKEEIRGL-RSHMDDLNSENAKLDAELIQYREDLN 2541
Query: 437 NKIPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRIS 496
I + + + E V +++N + N LE++ ++SE + +L+ S N+
Sbjct: 2542 QVITIKDSQQKQLLE-VQLQQNKELENKYAKLEEKLKESEEANEDLRR-----SFNA--- 2592
Query: 497 DDITDMISESKMD-NESLNSIHESLSNVTQPFL----EVTFNLNNFETSDTEEESQESNK 551
+ E K D ++ + S+ S+S +T+ E T L + + EEE +
Sbjct: 2593 ------LQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSA 2646
Query: 552 ISQDSESWVKDI---LVNDGNSCFQKRSENTNCEEIEGEHLPFLTSVSDKPTVTFPVKET 608
+ S+ + ++ LV +K E + + E +HL + T T +E
Sbjct: 2647 LFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETET--AEER 2704
Query: 609 LPSQFCDKTYVGFDMGICKTENTG--KEIEEYSDTLSNFESFKWTDAVYGDNKEDANKPI 666
+ D + + + EN G +I+ + ++S+ + ++++ AN+ +
Sbjct: 2705 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQ----------NSRDHANEEL 2754
Query: 667 QEVRINYDFA---LPPNKSKGINMNLHIPHIQNQIAENSNLFSEDAQPQPFILGSDLDKN 723
E++ YD + L K +G+ +N + ++ A + N E++ L L
Sbjct: 2755 DELKRKYDASLKELAQLKEQGL-LNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSK 2813
Query: 724 DEHVLPSTSSSDNSVQLLNTNQNHYECIA-LDKSNTHISNSL 764
DE +L +S ++S N Q+ + +A L H+ N L
Sbjct: 2814 DEQLLHLSSQLEDS---YNQVQSFSKAMASLQNERDHLWNEL 2852
Score = 34.3 bits (77), Expect = 0.64
Identities = 45/211 (21%), Positives = 84/211 (39%), Gaps = 14/211 (6%)
Query: 356 EDDVNSNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNND--------PSWNQEVKLEIP 407
E V N KD +Q++ + +++ + + S +D W ++ I
Sbjct: 2161 EIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQ 2220
Query: 408 SFNESSSLQVTCSSAENDGILSESDIQEDNKIPFN--QNDKGCIKESVLIKENAQEVNTC 465
S E L+ S D + S E+ KI + ++DK I ES E + C
Sbjct: 2221 SKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQ-IWESKAQTEVQLQQKVC 2279
Query: 466 GTLEKEYEQSESSLPELKHLQIESSNN-SRISDDITDMISESKMDNESLNSIHESLSNVT 524
TL+ E ++ S L E +HL S N +++ ++ + + + SL E N+
Sbjct: 2280 DTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2339
Query: 525 QPFLEVTFNLNN--FETSDTEEESQESNKIS 553
+ ++ N F E + Q S +++
Sbjct: 2340 GIIRQQEADIQNSKFSYEQLETDLQASRELT 2370
Score = 32.3 bits (72), Expect = 2.4
Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 9/111 (8%)
Query: 220 GNKLSDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEELNSEMTEHFP 279
G + S + + P + SL S + QN R + +L LK+ + +N E+TE P
Sbjct: 2861 GKQRSAAQPSTSPAEVQSLKKAMSSL-QNDRDR--LLKELKNLQQQYLQ-INQEITELHP 2916
Query: 280 QKQPQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMY 330
K + TK + I QEE + ENL +QH+ KS W ++
Sbjct: 2917 LKAQLQEYQDKTK-AFQIMQEELRQ----ENLSWQHELHQLRMEKSSWEIH 2962
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 35.8 bits (81), Expect = 0.22
Identities = 67/337 (19%), Positives = 122/337 (36%), Gaps = 53/337 (15%)
Query: 224 SDSLLTNEPVKRDSLASHYSGVSQNIRSKAQILALLKSESSSSCEEL---NSEMTEHFPQ 280
S LLT E K + + Q K+Q L+ L+ E+ EEL E+T H
Sbjct: 1094 SKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKL 1153
Query: 281 KQPQGSLKIATKPKYLIQQEECAEMKSTENLYYQHQSENTMRNKSRWAMYLSSQSSPIHS 340
++ + L + EMK E+ + + E +S I S
Sbjct: 1154 EEERSVL-----------NNQLLEMKKRESKFIKDADEEKAS---------LQKSISITS 1193
Query: 341 STVDGNDTERKPKAQEDDV--NSNLKDLSLQKIIQFVETYAEERKKYNVDQSVGNNDPSW 398
+ + D E + E V N SL ++Q +E+ K ++ V
Sbjct: 1194 ALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLES-----DKVKLELKVK------ 1242
Query: 399 NQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQEDNKIPFNQNDKGCIKESVLIKEN 458
N E++L+ SSS T + A+ D ES I N + + K + + +
Sbjct: 1243 NLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMS 1302
Query: 459 AQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRISDDITDMI---------SESKMD 509
+N G Y+ + + +S R+ DI D ++++M
Sbjct: 1303 EAALNGNGDDLNNYDSDDQ--------EKQSKKKPRLFCDICDCFDLHDTEDCPTQAQMS 1354
Query: 510 NESLNSIHESLSNVTQPFLEVTFNLNNFETSDTEEES 546
+ +S H +P+ E+ ++ T+ ++E+
Sbjct: 1355 EDPPHSTHHGSRGEERPYCEICEMFGHWATNCNDDET 1391
Score = 35.0 bits (79), Expect = 0.38
Identities = 72/328 (21%), Positives = 126/328 (38%), Gaps = 71/328 (21%)
Query: 250 RSKAQILALLKSESSSSCEELNSEMTEHFPQKQPQGSLKIATKPKYLIQQEECAEMKST- 308
+ + ++AL KS+ L + + H +Q LK++ + E AE+K+
Sbjct: 568 KENSDVIALWKSK-------LETAIASH---QQAMEELKVSFSKGLGTETAEFAELKTQI 617
Query: 309 --ENLYYQHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVNSNLKDL 366
L YQH+ EN + D+ER A+E +
Sbjct: 618 EKMRLDYQHEIENLQNQQ----------------------DSERAAHAKEMEALR----A 651
Query: 367 SLQKIIQFVETYAEE-RKKYNV--DQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCSSAE 423
L K+I+ E E R K + DQ + + + N+ + EI E LQ C+
Sbjct: 652 KLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEI-KVKELEVLQAKCNEQT 710
Query: 424 N--DGILSESDIQEDNKIPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLPE 481
D S+ E+ + + K E E ++K +Q E++ +
Sbjct: 711 KVIDNFTSQLKATEEKLLDLDALRKAS-------SEGKSE------MKKLRQQLEAAEKQ 757
Query: 482 LKHLQIESSNNSRISDDITDMISESKMDNESLNSIHESLSNVTQ---------PFLEVTF 532
+KHL+IE + S + IT + ++ L ++ E+LS V+Q L+ F
Sbjct: 758 IKHLEIEKNAESSKASSITRELQGREL---KLTNLQENLSEVSQVKETLEKELQILKEKF 814
Query: 533 NLNNFETSDTEEESQES-NKISQDSESW 559
+ E + QE+ NK+ Q E +
Sbjct: 815 AEASEEAVSVQRSMQETVNKLHQKEEQF 842
Score = 32.7 bits (73), Expect = 1.9
Identities = 53/252 (21%), Positives = 106/252 (42%), Gaps = 28/252 (11%)
Query: 323 NKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQFVETYAE-- 380
NKS+ + + +Q ++ T ++ AQ+ S L++ +++ + + E
Sbjct: 1092 NKSKELLTVENQKMEEFRKEIE---TLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVT 1148
Query: 381 ERKKYNVDQSVGNND--PSWNQEVKLEIPSFNESSSLQVTCSSAENDGILSESDIQED-- 436
+K ++SV NN +E K + E +SLQ + S +L+E D + +
Sbjct: 1149 SHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITS--ALLTEKDAELEKL 1206
Query: 437 -NKIPFNQNDKGCIKESVLIKENAQEVNTCGTLEKEYEQSESSLPELKHLQIESSNNSRI 495
N++ + + K + + + LE + + E L E K SS N+
Sbjct: 1207 RNEVTVLRGENASAKSLHSVVQTLESDKV--KLELKVKNLELQLKENKRQLSSSSGNTDT 1264
Query: 496 SDDITDMISESKMDNESLNSI-------HESLSNVTQPFLEVTFN-----LNNFETSDTE 543
D + ES++D LNS+ ++ L + E N LNN+++ D E
Sbjct: 1265 QADEDERAQESQID--FLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQE 1322
Query: 544 EESQESNKISQD 555
++S++ ++ D
Sbjct: 1323 KQSKKKPRLFCD 1334
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,482,660
Number of Sequences: 37866
Number of extensions: 1945496
Number of successful extensions: 5124
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 150
Number of HSP's that attempted gapping in prelim test: 4945
Number of HSP's gapped (non-prelim): 328
length of query: 1062
length of database: 18,247,518
effective HSP length: 113
effective length of query: 949
effective length of database: 13,968,660
effective search space: 13256258340
effective search space used: 13256258340
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.