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Search of human proteins with 37595528
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens]
(858 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens] 1711 0.0
gi|37595530 polyhomeotic-like 2 isoform b [Homo sapiens] 649 0.0
gi|62953127 polyhomeotic 1-like [Homo sapiens] 387 e-107
gi|148612879 polyhomeotic like 3 [Homo sapiens] 285 1e-76
gi|32699038 sterile alpha motif domain containing 7 [Homo sapiens] 80 6e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 2e-13
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 75 3e-13
gi|158138528 l(3)mbt-like 4 [Homo sapiens] 74 4e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni... 74 4e-13
gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens] 74 6e-13
gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens] 74 6e-13
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 74 6e-13
gi|47132519 Ras association and pleckstrin homology domains 1 is... 74 8e-13
gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens] 74 8e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 73 1e-12
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 69 2e-11
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 68 4e-11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 67 5e-11
gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ... 67 7e-11
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 66 2e-10
gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens] 65 2e-10
gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens] 65 2e-10
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 64 5e-10
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 64 5e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 6e-10
gi|53692193 Scm-like with four mbt domains 1 [Homo sapiens] 64 6e-10
gi|53692191 Scm-like with four mbt domains 1 [Homo sapiens] 64 6e-10
gi|53692195 Scm-like with four mbt domains 1 [Homo sapiens] 64 6e-10
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 64 8e-10
gi|110832843 TBP-associated factor 4 [Homo sapiens] 63 1e-09
>gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens]
Length = 858
Score = 1711 bits (4430), Expect = 0.0
Identities = 858/858 (100%), Positives = 858/858 (100%)
Query: 1 MENELPVPHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVI 60
MENELPVPHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVI
Sbjct: 1 MENELPVPHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVI 60
Query: 61 QQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQG 120
QQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQG
Sbjct: 61 QQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQG 120
Query: 121 STSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALT 180
STSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALT
Sbjct: 121 STSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALT 180
Query: 181 ASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGP 240
ASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGP
Sbjct: 181 ASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGP 240
Query: 241 TPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSV 300
TPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSV
Sbjct: 241 TPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSV 300
Query: 301 PGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQ 360
PGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQ
Sbjct: 301 PGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQ 360
Query: 361 PPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGS 420
PPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGS
Sbjct: 361 PPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGS 420
Query: 421 QQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEK 480
QQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEK
Sbjct: 421 QQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEK 480
Query: 481 SVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSPGMTSGN 540
SVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSPGMTSGN
Sbjct: 481 SVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSPGMTSGN 540
Query: 541 GNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKK 600
GNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKK
Sbjct: 541 GNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKK 600
Query: 601 YAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRF 660
YAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRF
Sbjct: 601 YAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRF 660
Query: 661 CSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTV 720
CSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTV
Sbjct: 661 CSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTV 720
Query: 721 PLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLV 780
PLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLV
Sbjct: 721 PLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLV 780
Query: 781 GMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNI 840
GMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNI
Sbjct: 781 GMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNI 840
Query: 841 KLGPALKIYARISMLKDS 858
KLGPALKIYARISMLKDS
Sbjct: 841 KLGPALKIYARISMLKDS 858
>gi|37595530 polyhomeotic-like 2 isoform b [Homo sapiens]
Length = 323
Score = 649 bits (1675), Expect = 0.0
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 536 MTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVG 595
MTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVG
Sbjct: 1 MTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVG 60
Query: 596 NLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFK 655
NLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFK
Sbjct: 61 NLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFK 120
Query: 656 RSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQ 715
RSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQ
Sbjct: 121 RSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQ 180
Query: 716 PTGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMH 775
PTGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMH
Sbjct: 181 PTGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMH 240
Query: 776 MRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLM 835
MRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLM
Sbjct: 241 MRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLM 300
Query: 836 SAMNIKLGPALKIYARISMLKDS 858
SAMNIKLGPALKIYARISMLKDS
Sbjct: 301 SAMNIKLGPALKIYARISMLKDS 323
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 387 bits (995), Expect = e-107
Identities = 359/1071 (33%), Positives = 483/1071 (45%), Gaps = 298/1071 (27%)
Query: 17 TSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQ 76
T S ++S++G +SSSGGS RP Q+S+Y +RQ VQ +Q AL RQP+ AAQY
Sbjct: 3 TESEQNSNSTNG--SSSSGGSSRPQIAQMSLY----ERQAVQALQ-ALQRQPN-AAQYFH 54
Query: 77 QMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSG-SNVSAQAPAQS 135
Q + QQ LS+AQL SLAAVQQA++ ++RQ S+ S Q
Sbjct: 55 QF--------------MLQQQLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQ 100
Query: 136 SSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMYLRAQM--- 192
+SINLA + +AAQL++R+QSV+S +A+ + Q +VLLGNT+SP L SQAQMYLR Q+
Sbjct: 101 ASINLATT-SAAQLISRSQSVSSPSATTLTQ-SVLLGNTTSPPLNQSQAQMYLRPQLGNL 158
Query: 193 ----------------LIFTPTATVATVQPEL---------------------------- 208
LI P VA VQ E+
Sbjct: 159 LQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQ 218
Query: 209 -----GTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGS---- 259
G+ A PP + V +L+ + Q A A + T SL L GGS
Sbjct: 219 GPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQ---SLNLSQAGGGSGNSI 275
Query: 260 -------------------------------------QPLPTPAQSRNTAQASPAGAKPG 282
QPLP AQ+ +Q S A+
Sbjct: 276 PGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPA-AQTVTVSQGSQTEAESA 334
Query: 283 IADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPA-YAQLQPHQLLPQPSS 341
A KK + + S G L+RT + LI+ A Y Q+QPH L+ Q
Sbjct: 335 AA-------KKAEADGS--GQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQ 385
Query: 342 KHLQPQFVI-----------------------------------QQQPQPQQQQP----- 361
HLQ + V+ QQQ Q QQQQP
Sbjct: 386 IHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTL 445
Query: 362 --------------PPQQSR---------PVLQAEP------------------------ 374
PP QS+ P+LQ+ P
Sbjct: 446 TAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPI 505
Query: 375 -HPQLASVSPSVALQP---------------SSEAHAMPLGPVTPALP--------LQCP 410
PQL + S A QP +++A A+ L + A+P +Q
Sbjct: 506 KPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSG 565
Query: 411 TANL-------HKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASP 463
A+L PG Q+C PPT G +G H + +S V+ Q+ PA+
Sbjct: 566 QAHLASSPPSSQAPGALQEC-PPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQV-PAAF 623
Query: 464 PQQCVPDDWKEVAPGE-KSVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQP-------S 515
Q V PG+ +++ R S ++ V+ + LP SP + S
Sbjct: 624 YMQSVH------LPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKS 677
Query: 516 PAHETGQGIVHALTDLSSP---GMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHV 572
E + + + + S +T ++A + Q G++KPPQAIVKPQILTH+
Sbjct: 678 SLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHI 737
Query: 573 IEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESK 632
IEGFVIQEGAEPFPVG S LL K ++ L LP T T+++ P +S
Sbjct: 738 IEGFVIQEGAEPFPVGCSQLL------KESEKPLQTGLP----TGLTENQSGGPLGVDSP 787
Query: 633 EEGAPLK---LKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQK 689
K LKCE CG+ A +F+ SKRFCSM CAKRYNV C+ + L + Q+
Sbjct: 788 SAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRKKMKEFQE 847
Query: 690 AGAATHNRRRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEP 749
A A RR ++S + + + G + QEDSSR SDNSSY+E
Sbjct: 848 ANYARVRRRGPRRSS----SDIARAKIQG----------KCHRGQEDSSRGSDNSSYDEA 893
Query: 750 LSPISASSSTSRRRQGQRDLELPDMH--MRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLP 807
LSP S + R G+RDL P+ +L G+ FL S P++W+VE+VYEFI SL
Sbjct: 894 LSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQ 953
Query: 808 GCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS 858
GCQEIAEEFR+QEIDGQALLLLKE+HLMSAMNIKLGPALKI A+I++LK++
Sbjct: 954 GCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET 1004
>gi|148612879 polyhomeotic like 3 [Homo sapiens]
Length = 995
Score = 285 bits (729), Expect = 1e-76
Identities = 290/924 (31%), Positives = 413/924 (44%), Gaps = 120/924 (12%)
Query: 11 SSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQAL---HRQ 67
SS +TS T + S + +S S PT Q+ S + + QQ +
Sbjct: 116 SSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTS 175
Query: 68 PSTAAQYLQQMYAAQQQHLMLQT--AALQQQ-----HLSSAQLQSLAA-VQQASLVSNRQ 119
P+ A Q AQ T AA+Q SS+ QS A VQ +L S +
Sbjct: 176 PTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKL 235
Query: 120 GSTSGS-NVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPA 178
G S S N ++ +Q+ S+ + + +Q S ++ + L +++
Sbjct: 236 GVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVT 295
Query: 179 LTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAAS 238
T+S Q+ A P + + Q L + PP+ L L+ QQ +
Sbjct: 296 RTSSIHQLIAPASYSPIQPHSLIKHQQIPLHS-----PPSKVSHHQLILQQQQQQIQPIT 350
Query: 239 GPTPTQPVLPSLALKPTPG-GSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGN 297
TQ PS P G P P+ AQS++ SP + P + + P++
Sbjct: 351 LQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQH---CSPIQSHP--SPLTVSPNQSQSAQ 405
Query: 298 SSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQ 357
SV S S++ P + HP A +QPH L+ S LQP +QQ Q
Sbjct: 406 QSVVVSPPPPHSPSQS-PTIIIHP-----QALIQPHPLV----SSALQPGPNLQQSTANQ 455
Query: 358 QQQPP--------PQQSRPVLQAEPHPQLASVSP-----SVALQPSSEAHAMPLGPVTP- 403
Q P + PV+ P Q A VSP S + Q S + P+ +P
Sbjct: 456 VQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPP 515
Query: 404 ----ALPLQCPTANLHKPGGSQQCHPPTPDTGP---QNG--HPEGVPHTP---QRRFQ-- 449
+ P Q P L S Q P G QN E +P Q FQ
Sbjct: 516 QMSTSPPAQIPPLPLQSMQ-SLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTL 574
Query: 450 ---HTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPET--------RSGPSPHQQAIVT 498
T AV LQ+QP +P V ++V E+ +PE R+ P P
Sbjct: 575 PPPQTVAVNLQVQPPAPVDPPVVYQVEDVC--EEEMPEESDECVRMDRTPPPPTLSPAAI 632
Query: 499 AMPGGLPV----PTSPNIQPSPAHETGQGIVHALTDLSSPG-------MTSGNGNSASSI 547
+ G + P ++ ++ + +D S + + S S+
Sbjct: 633 TVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTS 692
Query: 548 AGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKY------ 601
++ + ENKPPQAIVKPQILTHVIEGFVIQEG EPFPV RSSLL+ KK
Sbjct: 693 MHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQ 752
Query: 602 ---AQGFLPEKLPQQDHT-TTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRS 657
+ PE H ++D+EME+ +E+ EE LKCE CG++ +A +F RS
Sbjct: 753 VINSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLRS 812
Query: 658 KRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPT 717
KRFC+M+CAKRYNV C+K+ L +R ++ H RR S P
Sbjct: 813 KRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQS--LGHRGRRPSG-------------PD 857
Query: 718 GTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMR 777
G + L +T+ + D +S+E+ + P + ++ R+ + +R+ EL D+ +R
Sbjct: 858 GAAREHILRQLPITYPSAEE----DLASHEDSV-PSAMTTRLRRQSERERERELRDVRIR 912
Query: 778 DLVGMGHHFLP---SEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHL 834
+ LP +EP+ W V+DV+ FI SLPGCQ+IA+EFRAQEIDGQALLLLKEDHL
Sbjct: 913 KMPE-NSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHL 971
Query: 835 MSAMNIKLGPALKIYARISMLKDS 858
MSAMNIKLGPALKI ARI+ LK+S
Sbjct: 972 MSAMNIKLGPALKICARINSLKES 995
Score = 261 bits (668), Expect = 1e-69
Identities = 217/552 (39%), Positives = 282/552 (51%), Gaps = 88/552 (15%)
Query: 6 PVPHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALH 65
P P TSS + TSST+ + ++ S R PQISVYSG DR VQVIQQALH
Sbjct: 17 PNPGTSSVSTTTSSTTTTTITTS--------SSRMQQPQISVYSG-SDRHAVQVIQQALH 67
Query: 66 RQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGS 125
R PS+AAQYLQQMYAAQQQHLML TAALQQQHLSS+QLQSLAAV QASL S R ++
Sbjct: 68 RPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAV-QASLSSGRPSTSPTG 126
Query: 126 NVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQ 185
+V+ Q+ +SINL+ SP AQL++R+Q+ +S + S I QQ +LLG+T SP LTASQAQ
Sbjct: 127 SVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGS-ITQQTMLLGST-SPTLTASQAQ 184
Query: 186 MYLRAQMLIFTPTATVATVQPEL----GTGSPARPPTPAQVQNLTLRTQQTPAAAASGPT 241
MYLRAQMLIFTP TVA VQ ++ + S + QVQNLTLR+Q+ ++S
Sbjct: 185 MYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNG 244
Query: 242 PTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVP 301
P + + +L T ++ T +S + D E +KKG+
Sbjct: 245 PPKSTSQTQSL-----------TICHNKTTVTSSKISQR----DPSPESNKKGES----- 284
Query: 302 GSMEGRA-GLSRTVPAVAAHPLIAPA-YAQLQPHQL-------LPQPSSKHLQPQFVIQQ 352
S+E R+ ++RT + H LIAPA Y+ +QPH L L P SK Q ++QQ
Sbjct: 285 PSLESRSTAVTRT---SSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQ 341
Query: 353 QPQPQQ--------QQPPPQQSRPVLQ------------------AEPHPQLASVSPSVA 386
Q Q Q Q PPP Q LQ + HP +VSP+
Sbjct: 342 QQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPN-- 399
Query: 387 LQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDT-GPQNGHPEGVPHTPQ 445
Q S ++ + P P P Q PT +H P Q HP P + + Q
Sbjct: 400 -QSQSAQQSVVVSPPPPHSPSQSPTIIIH-PQALIQPHPLVSSALQPGPNLQQSTANQVQ 457
Query: 446 RRFQHTSAVILQLQPASPPQQCVPDDWKE-VAPGEKSVPETRSGPSPHQQAIVTAMPGGL 504
Q L L PASP P V+PG++ V SP Q + +
Sbjct: 458 ATAQLNLPSHLPL-PASPVVHIGPVQQSALVSPGQQIV-------SPSHQQYSSLQSSPI 509
Query: 505 PVPTSPNIQPSP 516
P+ + P + SP
Sbjct: 510 PIASPPQMSTSP 521
>gi|32699038 sterile alpha motif domain containing 7 [Homo sapiens]
Length = 446
Score = 80.5 bits (197), Expect = 6e-15
Identities = 40/83 (48%), Positives = 54/83 (65%), Gaps = 1/83 (1%)
Query: 771 LPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLK 830
LP H +G G+ L + KW V+DV+ FIRSLPGC + A+ F+ IDG+ L LL
Sbjct: 305 LPGTHALVTIG-GNLSLDEDIQKWTVDDVHSFIRSLPGCSDYAQVFKDHAIDGETLPLLT 363
Query: 831 EDHLMSAMNIKLGPALKIYARIS 853
E+HL M +KLGPALKI +++S
Sbjct: 364 EEHLRGTMGLKLGPALKIQSQVS 386
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 75.5 bits (184), Expect = 2e-13
Identities = 105/418 (25%), Positives = 150/418 (35%), Gaps = 67/418 (16%)
Query: 115 VSNRQGSTSGSNVSAQAP-------AQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQ 167
++ R G G+ + AP A +SS N A+ P A+ RA + + ++
Sbjct: 58 LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117
Query: 168 AVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGS--PARPPTPAQVQNL 225
G T L Q + + A+ + AT A + L G+ PTP
Sbjct: 118 GRASGTTRPGPL--GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175
Query: 226 TLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAK-PGIA 284
R + P P PS +P G + + A +T + SPA + P
Sbjct: 176 MARRSRAAGTEVGLPRPA----PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 285 DSVMEPHKKGDGNSSVPGSMEGRAGLS-RTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKH 343
+ P + +S+ P S R+G S R P AHP QP K
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP---------------SQPKPKG 276
Query: 344 LQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTP 403
LQ +P Q PP + + P L LA+ SPS ALQ + A P P TP
Sbjct: 277 LQAL-------RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ----SQAPPTLPATP 325
Query: 404 -ALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVP--------HTPQRRFQHTSAV 454
+ L C A PP+ T P P P +P + H+
Sbjct: 326 HSSSLTCQLATPLPLAPPSPSAPPSLQTLPS---PPATPPSQATTSLGSPTLQATHSFLP 382
Query: 455 ILQLQP-ASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSPN 511
L P A+PP Q AP ++P ++ PSP A P P P +PN
Sbjct: 383 SPPLSPLATPPPQ---------APPALALPPLQAPPSP--PASPPLSPLATPSPQAPN 429
Score = 58.2 bits (139), Expect = 3e-08
Identities = 144/628 (22%), Positives = 211/628 (33%), Gaps = 104/628 (16%)
Query: 8 PHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALHRQ 67
P S S+ + ST+ S ++ S+ GG RP +S + +
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS--------SSATPLSSPARSG 256
Query: 68 PSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGSNV 127
PS + +Q + LQ AL+ ++ + + A+ S S S + +
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQ--ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAA-L 313
Query: 128 SAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMY 187
+QAP L A+P ++ L + + A + L S PA SQA
Sbjct: 314 QSQAPP-----TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
Query: 188 LRAQMLIFTPTATVATVQPELGTGSPARPPTPA--QVQNLTLRTQQTPAAAASGPTPTQP 245
L + L T + + L T P PP A +Q P + + P+P P
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 428
Query: 246 VLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSME 305
++ L P P P P Q A SP A P ++ S P
Sbjct: 429 NALAVHLLQAPFSPPPSP-PVQ----APFSPP-ASPPVSPSATPP--------------- 467
Query: 306 GRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQ 365
S+ P++AA PL P P P S PQ P Q PP Q
Sbjct: 468 -----SQAPPSLAAPPLQVPPSPPASP----PMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518
Query: 366 SRPVLQAEP----------HPQLASVSPSVALQPSSEAHAMPLGPVTPALP-LQCPTANL 414
+ P L P P A SPS +L S A P P A P LQ P +
Sbjct: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578
Query: 415 HKPGGSQQCHPPTPDTGPQNGHPE-------GVPHTPQRRFQHTSAVILQLQPASPPQQC 467
P PPTP P G P P R T + L S
Sbjct: 579 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG-PDLAGHSSSATS 637
Query: 468 VPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAM-----------------PGGLPVPTSP 510
P++ + G S PE + SP A + A G P+P P
Sbjct: 638 TPEELR----GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 693
Query: 511 NIQPSPAH-----------ETGQGIVHALTDLSSPGMTSGNGNSASSIAGTAPQNGE--- 556
P A E+ AL SPG TSG +A + AG + ++ +
Sbjct: 694 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG-TSGGKAAAGAGAGASSRSPKQAR 752
Query: 557 -NKPPQAIVKPQILTHVIEGFVIQEGAE 583
+ P ++ ++ H++ ++ AE
Sbjct: 753 LGELPLGALQASVVQHLLSRTLLLAAAE 780
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 74.7 bits (182), Expect = 3e-13
Identities = 108/466 (23%), Positives = 170/466 (36%), Gaps = 64/466 (13%)
Query: 112 ASLVSNRQGSTSGSNVSA--QAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAV 169
AS+VS + + + VSA +A + ++++ AA ++ + A A+ I Q+ +
Sbjct: 886 ASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGM 945
Query: 170 LLGNTSSPALTASQAQMYLRAQMLI----FTPTATV-ATVQPELGTGSPARPPTPAQVQN 224
SP A + + + TP TV A +P+ + P PA
Sbjct: 946 SAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAA 1005
Query: 225 LTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQP---LPTPAQSRNTAQASPAGAKP 281
++ + AA+ PTP +P P+ A+ P + P +PTP + + A A P +P
Sbjct: 1006 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1065
Query: 282 -GIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPS 340
A +V P + ++VP E T PA A +P P
Sbjct: 1066 TSPAAAVPTPEEPTSPAAAVPTPEE------PTSPAAA-----------------VPTP- 1101
Query: 341 SKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGP 400
++ P P P++ A P P+ +P+S A A+P P
Sbjct: 1102 ----------EEPTSPAAAVPTPEEPASPAAAVPTPE----------EPASPAAAVPT-P 1140
Query: 401 VTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQP 460
PA P P + S PTP+ ++ P TP +AV+ L+
Sbjct: 1141 EEPAFP--APAVPTPEESASAAVAVPTPE---ESASPAAAVPTPAESASF-AAVVATLEE 1194
Query: 461 ASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAHET 520
+ P VP VA E+ S P+ + A + A PTSP E
Sbjct: 1195 PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEP 1254
Query: 521 GQGIVHALT--DLSSPGMTSGNGNSASSIAGTAPQNGENKPPQAIV 564
LT +LSSP + +S A E P A V
Sbjct: 1255 TSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAV 1300
>gi|158138528 l(3)mbt-like 4 [Homo sapiens]
Length = 623
Score = 74.3 bits (181), Expect = 4e-13
Identities = 41/93 (44%), Positives = 60/93 (64%), Gaps = 2/93 (2%)
Query: 767 RDLELP-DMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQA 825
RDL L + H + L G+ S+ +W V++V EF++SL GC+E A+ F+ ++IDG+A
Sbjct: 516 RDLPLGREQHCKLLPGVAD-IRASQVARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKA 574
Query: 826 LLLLKEDHLMSAMNIKLGPALKIYARISMLKDS 858
LLL + ++ M IKLGPALKIY I M + S
Sbjct: 575 FLLLTQTDIVKVMKIKLGPALKIYNSILMFRHS 607
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 74.3 bits (181), Expect = 4e-13
Identities = 108/433 (24%), Positives = 152/433 (35%), Gaps = 53/433 (12%)
Query: 116 SNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTS 175
S ++ T S SA A ++ + LA SP+ + Q+ G A +GN S
Sbjct: 766 SPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLS 825
Query: 176 SPALTASQAQMYLRAQMLIF-----TPTATVATVQPELGTGSPARPPTPAQV-----QNL 225
SP + +L L F +P T + P SP PTP+ V + +
Sbjct: 826 SPVSPVEAS--FLPENSLSFQGSKDSPATTHSPTPP-----SPKGAPTPSAVTPLSPKGV 878
Query: 226 TLRTQQTPAAAA-------SGP-TPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPA 277
TL ++TP + GP TP P+L++ + + TPA A SP
Sbjct: 879 TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSM-TSSSPKKARATPAPKGIPASPSPK 937
Query: 278 GAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLI-APAYAQLQPHQLL 336
GA A + P G + P + T P+ P +P A P
Sbjct: 938 GAPTPPAATPPSP----KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993
Query: 337 PQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVA-LQPSSEAHA 395
P P P + P P PP + P A P P+ AS P+ P A
Sbjct: 994 PSPKGGPATPS--PKGAPTPPAVTPPSPKGSPA--ATPFPKGASTPPAATPPSPKGSPAA 1049
Query: 396 MPL---GPVTPALPLQCP-----TANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRR 447
PL P TPA L P T +L PP+P GP P+G P P
Sbjct: 1050 TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT 1109
Query: 448 FQHTSAVILQLQPASPPQQCVPDDWKEVAPGEK---SVPETRSGPSPHQQAIVTAMPGGL 504
+ A+PP + P P K + P + P+ A + GGL
Sbjct: 1110 PPSPKGGL-----ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT-PAATPPSPKGGL 1163
Query: 505 PVPTSPNIQPSPA 517
P +PA
Sbjct: 1164 ATPPPKGAPTTPA 1176
Score = 70.9 bits (172), Expect = 5e-12
Identities = 99/380 (26%), Positives = 133/380 (35%), Gaps = 55/380 (14%)
Query: 199 ATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGG 258
+T P GSPA P P T +P + P+ P A P+P G
Sbjct: 1033 STPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092
Query: 259 SQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGN-SSVPGSMEGRAGLSRTVPAV 317
P+P + A+P K G+A PHK ++ P S +G GL+ P
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLA---TPPHKGAPTTPAATPPSPKG--GLATPPPKG 1147
Query: 318 AAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQ 377
A PA P L P K P P P+ A P P+
Sbjct: 1148 AP---TTPAATPPSPKGGLATPPPK--------GAPTTPAATPPSPKGG----LATPSPK 1192
Query: 378 LASVSPSVALQPSSE---AHAMPLG-PVTPALPLQCPTANLHKPG-----GSQQCHPPTP 428
A +P+ A PS + A P G P TPA P L P + PP+P
Sbjct: 1193 GAPTTPA-ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1251
Query: 429 DTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSG 488
GP P+G P P + L+ A+PP + P+ P + P + G
Sbjct: 1252 KGGPATPPPKGAPTPPA-----ATPPSLKGGLATPPHKGAPN------PAVVTPPSPKGG 1300
Query: 489 PSPHQQAIVTAMPGGLP-----VPTSPNIQPSPAHETGQGIVHALTDLSSPGMTSGNGNS 543
P+ T+ P G P P SP P G A+T S G + +
Sbjct: 1301 PA-------TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 544 ASSIAG-TAPQNGENKPPQA 562
SS G T P + E P A
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPA 1373
Score = 66.2 bits (160), Expect = 1e-10
Identities = 92/393 (23%), Positives = 128/393 (32%), Gaps = 59/393 (15%)
Query: 197 PTATVATVQPELGTGSPA-----RPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLA 251
P ++ + P+ +PA P+P T +P + P+P P A
Sbjct: 909 PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 252 LKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIA----------DSVMEPHKKGDGNSSVP 301
P+P G P+P + A+P K G A +V P KG ++ P
Sbjct: 969 TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG-SPAATP 1027
Query: 302 GSMEGRAGLSRTVPAVAAHPLIA--PAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQ 359
+ T P+ P P A P LP P P ++ P P
Sbjct: 1028 FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPS--LKGAPTPPAA 1085
Query: 360 QPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPL---GPVTPALPLQCPTANLHK 416
PP + P A P P+ A + P+ A P P TPA P L
Sbjct: 1086 TPPSPKGGP---ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT 1142
Query: 417 P-----GGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDD 471
P + PP+P G P+G P TP A+PP
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP---------------AATPPS----PK 1183
Query: 472 WKEVAPGEKSVPETRSG--PSPHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALT 529
P K P T + PSP + + T P G P T PSP +G + +
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSP-KGGLATPSPKGAPT-TPAATPPSP-----KGGLATPS 1236
Query: 530 DLSSPGMTSGNGNSASSIAGTAPQNGENKPPQA 562
+P + S T P G PP A
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269
Score = 64.3 bits (155), Expect = 5e-10
Identities = 143/630 (22%), Positives = 207/630 (32%), Gaps = 121/630 (19%)
Query: 196 TPTATVATVQPELGTGSP-ARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKP 254
TP AT + + L T SP P TPA T +P + P+P A P
Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAA-------TPPSPKGGLATPSPKGAPTTPAATPP 1249
Query: 255 TPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTV 314
+P G P P + A+P K G+A P KG N +V + G + +
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLAT----PPHKGAPNPAVVTPPSPKGGPATSP 1305
Query: 315 PAVAAHPLIA-------------PAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQP----Q 357
P A P A P A P P P P + P
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365
Query: 358 QQQPPPQQSRPV-----LQAEPHPQLASVSPSVALQPSSEAHAMPLGPV-TPALPLQCPT 411
++ P P + P P P+ PS P+S A +PL P PA P+
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA-VIPLSPKKAPATPVTREG 1424
Query: 412 ANLHKPGG--SQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVP 469
A G P + P P+G P TP + T + P PP
Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP--- 1481
Query: 470 DDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLP-----VPTSPNIQPSPAHETGQGI 524
K+VA T S P ++A T P G P +P+SP P+ I
Sbjct: 1482 ---KQVA--------TSSSP---KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 525 VHALTDLSS--------------PGMTSGNGNSASSI-----AGTAPQNGENKPPQAIV- 564
T LS P MT + +I A P + E P A+
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587
Query: 565 ---------KPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDH 615
K ++ + +E P V S PEK P
Sbjct: 1588 STYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS---------------PEKGPATPA 1632
Query: 616 T--TTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGC 673
T T + L++S +P + C++ V A K +K+ K V
Sbjct: 1633 PKGTPTSPPVTPSSLKDSPT--SPASVTCKMGATVPQASKGLPAKK--GPTALKEVLVAP 1688
Query: 674 TKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTHS 733
+ + + A + + S A+ PP+ D + PLS A L
Sbjct: 1689 AP-------ESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPV 1741
Query: 734 QEDSSRCSD----NSSYEEPLSPISASSST 759
Q+DSS+ + + S + PL+P + +ST
Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKAST 1771
Score = 63.9 bits (154), Expect = 6e-10
Identities = 104/449 (23%), Positives = 165/449 (36%), Gaps = 39/449 (8%)
Query: 118 RQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNR-AQSVNSAAASGIAQQAVLLGNTSS 176
+Q +TS S +APA + + PA + + S+ IA A LL +
Sbjct: 1482 KQVATSSS--PKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539
Query: 177 PALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPAR-----PP--TPAQVQNLTLRT 229
L +A + M + +P T A P+ +P+ PP TP+ +
Sbjct: 1540 ATLAPKEA--LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597
Query: 230 QQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVME 289
+ A + P+P + P P+P P P + + +P+ K
Sbjct: 1598 ELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASV 1657
Query: 290 PHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFV 349
K G ++VP + +G ++ P L+APA + ++ P+ K Q +
Sbjct: 1658 TCKMG---ATVPQASKGLP--AKKGPTALKEVLVAPA---PESTPIITAPTRKGPQTKKS 1709
Query: 350 IQQQPQPQQQQPPPQQSR--PVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTP---- 403
P P P + P+ P P L S +A P GP+ P
Sbjct: 1710 SATSP-PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESK 1768
Query: 404 -ALPLQCPTAN--LHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQP 460
+ PL L KP + P+P P VP P ++ S+ L L+
Sbjct: 1769 ASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA-PSPVPTLPPKQQFLPSSPGLVLE- 1826
Query: 461 ASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIV---TAMPGGLPVPTSPNIQPSPA 517
SP + P D E+ P PE SG P Q +V T G+PVPT QP
Sbjct: 1827 -SPSKPLAPADEDELLP--LIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTK 1883
Query: 518 HETGQGIVHALTDLSSPGMTSGNGNSASS 546
+ G G + +D S P + + A++
Sbjct: 1884 NNKGSG-TESDSDESVPELEEQDSTQATT 1911
Score = 58.5 bits (140), Expect = 3e-08
Identities = 88/360 (24%), Positives = 134/360 (37%), Gaps = 50/360 (13%)
Query: 198 TATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPG 257
T T V P SP P + T+ A GPT + VL + A + TP
Sbjct: 1636 TPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI 1695
Query: 258 GSQPLPTPAQSRNTAQASP-----AGAKPG-------IADSVMEPHKKGDGNSSVPGSME 305
+ P Q++ ++ SP AK G +A + + P +K D + + G
Sbjct: 1696 ITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQK-DSSKTAKGKDA 1754
Query: 306 GRAGLSRTVP--AVAAHPLIAPAYAQLQPHQLLPQPSSKHL----QPQFVIQQQPQPQQQ 359
+ P + A+ PL A A+ ++LP+P S + P + P P
Sbjct: 1755 SHSPKGPLAPPESKASTPLTAAAF-----EKVLPKPESASVSAAPSPPVSLPLAPSPVPT 1809
Query: 360 QPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPL---GPVTPALPLQCPTANLHK 416
PP QQ P P L SPS L P+ E +PL P++ +P Q N+
Sbjct: 1810 LPPKQQFLP-----SSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPT 1864
Query: 417 PGGSQQCHPPTPD-----------TGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQ 465
P S PTP +G ++ E VP ++ + QL A+
Sbjct: 1865 P-KSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID 1923
Query: 466 QCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAM-----PGGLPVPTSPNIQPSPAHET 520
+ P + + EK + S Q VT + L V T P++ SPA +T
Sbjct: 1924 E-EPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDT 1982
Score = 57.4 bits (137), Expect = 6e-08
Identities = 83/406 (20%), Positives = 139/406 (34%), Gaps = 64/406 (15%)
Query: 112 ASLVSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLL 171
A+ S++ G T+ S+ P ++ + R ++ S + + L
Sbjct: 1351 ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL 1410
Query: 172 GNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSP-ARPPTPAQVQNLTLRTQ 230
+PA ++ ++ + P T +++ T +P P TP+ + TL
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470
Query: 231 QTPAAAASGPTPTQPVLPSLALK----PTPGGSQPLPTP-AQSRNTAQASPAGAKPGIAD 285
TP + P P Q S K P P G+ LP S A+P+ + IA
Sbjct: 1471 -TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529
Query: 286 SVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQ 345
+ LS+ PA +AP A + P +P P
Sbjct: 1530 TA--------------------TLLSKKTPAT-----LAPKEALIPPAMTVPSPKKTPAI 1564
Query: 346 P-QFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPA 404
P P ++ PP + + P P+ + P+V EA P PA
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEA------PTPPA 1618
Query: 405 LPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPP 464
+ PP+P+ GP P+G P +P + L+ P SP
Sbjct: 1619 VT------------------PPSPEKGPATPAPKGTPTSPP-----VTPSSLKDSPTSPA 1655
Query: 465 QQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSP 510
V K +P + GP+ ++ +V P P+ T+P
Sbjct: 1656 SVTCKMG-ATVPQASKGLP-AKKGPTALKEVLVAPAPESTPIITAP 1699
Score = 42.4 bits (98), Expect = 0.002
Identities = 90/374 (24%), Positives = 128/374 (34%), Gaps = 61/374 (16%)
Query: 196 TPTATVA--TVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALK 253
+P AT+A ++ L G PA T N + +T + A GP P+L S +
Sbjct: 585 SPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA--GPDSAGPLLKSSLIT 642
Query: 254 PT----------PGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSS---- 299
PT P G P S T ASP G + H +G +
Sbjct: 643 PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF--LEGTVSLAPKNHPVKEGTLTTLPL 700
Query: 300 VPGSMEGR--AGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQ----PSSK------HLQPQ 347
VP + E A + A A ++AP + P LP P +K H
Sbjct: 701 VPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSAL 760
Query: 348 FVIQQQPQ--PQQQQ-----PPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGP 400
+ P+ P + + + L P P SVSP P+ + A P P
Sbjct: 761 APVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP 820
Query: 401 V----TPALPLQC---PTANLHKPGGSQQ---CHPPTPDTGPQNGHPEGVPHTPQRRFQH 450
+ +P P++ P +L G H PTP + P+G P TP
Sbjct: 821 IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS------PKGAP-TPSA-VTP 872
Query: 451 TSAVILQLQPASPPQQCVPD----DWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPV 506
S + L P P V + P K P S ++A T P G+P
Sbjct: 873 LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPA 932
Query: 507 PTSPNIQPSPAHET 520
SP P+P T
Sbjct: 933 SPSPKGAPTPPAAT 946
Score = 38.9 bits (89), Expect = 0.021
Identities = 117/526 (22%), Positives = 179/526 (34%), Gaps = 78/526 (14%)
Query: 127 VSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQM 186
V+ A QS +L + L + V S + G+ S + A +
Sbjct: 217 VTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAAL 276
Query: 187 YLRAQMLIFTPTATVATVQPE------LGTGSPARPPTPAQVQNLTLRTQQTPAAAASGP 240
L Q L T++ T P + GS P + ++ L Q P+A +
Sbjct: 277 SLSTQSLPVV-TSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPT 335
Query: 241 TPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGN-SS 299
T V S P +P P SRN + A P +A SV KG SS
Sbjct: 336 VKTISVDHSSTGASYPSQRSVIP-PLPSRNEVVPATVAAFPVVAPSV----DKGPSTISS 390
Query: 300 VPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQ-LLPQPSSKHLQPQFVIQQQPQPQQ 358
+ S G ++ + LI + H L+ Q + ++ P
Sbjct: 391 ITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIA 450
Query: 359 QQP-----------PPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPL 407
P PP S P+ EP SP+ A+ + PV P P
Sbjct: 451 AAPTTTFEVATCVSPPMSSGPISNIEP------TSPA----------ALVMAPVAPKEPS 494
Query: 408 QCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQQC 467
L P PP PD PE + + P S+V+++ P Q
Sbjct: 495 TQVATTLRIP-----VSPPLPD-------PEDLKNLP-------SSVLVKF-PTQKDLQT 534
Query: 468 VPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLP----VPTSPNIQPSPAHETGQG 523
VP E AP + + P +V A P P +SP I SP +
Sbjct: 535 VPAS-LEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKK 593
Query: 524 IVHALTDLSSP--GMTSGNG-NSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQE 580
+ + P MTS G NS++S+ T G + ++K ++T + F + E
Sbjct: 594 SLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDS-AGPLLKSSLITPTVAAFPL-E 651
Query: 581 GAEPFPVGRSSLLVGNLKKKYAQGFL-------PEKLPQQDHTTTT 619
A+P V ++ + A FL P+ P ++ T TT
Sbjct: 652 SADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTT 697
Score = 35.8 bits (81), Expect = 0.17
Identities = 86/392 (21%), Positives = 127/392 (32%), Gaps = 83/392 (21%)
Query: 198 TATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPG 257
T TV + EL +P V ++ T A GPT P P+ P
Sbjct: 6 TETVPATEQEL-----PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
Query: 258 GSQ-------------PLPTPAQSRNTAQASPAGAKP-------------------GIAD 285
+Q PL P ++ A P G P +A
Sbjct: 61 ANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALAS 120
Query: 286 SVMEPHKKGDGNSSVPGSMEGRA------------GLSRTVPAVAA---------HPLIA 324
++ P KG +SS P ++ A L + P+VA IA
Sbjct: 121 PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180
Query: 325 PAYAQLQ----PHQLLPQPSSKHLQPQFVIQQQP----QPQQQQPPPQQSRPVLQAEPHP 376
P+ + P +++P P P ++ P P S P Q P
Sbjct: 181 PSEPKTNLNKVPSEVVPNPKGTP-SPPCIVSTVPYHCVTPMASIQSGVASLP--QTTPTT 237
Query: 377 QLASVSP--------SVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTP 428
LA SP SV + P + GPV+P L T +L SQ+ P
Sbjct: 238 TLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQK--TAGP 295
Query: 429 DTGPQNGHPEGVPHTPQRRFQHTSAVIL-QLQPASPPQQCVPDDWKEVAPGEKSVPETRS 487
+T P G P + S +L Q P++ V + + S P RS
Sbjct: 296 NTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRS 355
Query: 488 --GPSPHQQAIVTAMPGGLPVPTSPNIQPSPA 517
P P + +V A PV +P++ P+
Sbjct: 356 VIPPLPSRNEVVPATVAAFPV-VAPSVDKGPS 386
>gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens]
Length = 755
Score = 73.9 bits (180), Expect = 6e-13
Identities = 33/68 (48%), Positives = 51/68 (75%)
Query: 789 SEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKI 848
S+ +KW+ ++V EFI+SLPGC+E + F+ ++IDG+A LL+ + ++ M+IKLGPALKI
Sbjct: 678 SKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKI 737
Query: 849 YARISMLK 856
+ I M K
Sbjct: 738 FNSILMFK 745
>gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens]
Length = 780
Score = 73.9 bits (180), Expect = 6e-13
Identities = 33/68 (48%), Positives = 51/68 (75%)
Query: 789 SEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKI 848
S+ +KW+ ++V EFI+SLPGC+E + F+ ++IDG+A LL+ + ++ M+IKLGPALKI
Sbjct: 703 SKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKI 762
Query: 849 YARISMLK 856
+ I M K
Sbjct: 763 FNSILMFK 770
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 73.9 bits (180), Expect = 6e-13
Identities = 110/424 (25%), Positives = 154/424 (36%), Gaps = 103/424 (24%)
Query: 162 SGIAQQAVLLGNTSSPALTA-SQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPA 220
S + Q ++ G S P L+ S+ LR + AT EL P A
Sbjct: 2 SALLQDPMIAGQVSKPLLSVRSEMNAELRGE-------DKAATSDSELNE------PLLA 48
Query: 221 QVQNLTLRTQQTPA---AAASGPTPTQPVLP-----SLALKPTPGGSQPLPTPAQSRNTA 272
V++ ++ TP+ A P + P P S P P G QPL T Q +
Sbjct: 49 PVESND--SEDTPSKLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAV 106
Query: 273 QASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAA---HPLIAPAYA- 328
G P + ++ P ++ G + G+ GL T+P L+A A A
Sbjct: 107 AGVMPGGPPALNQPILIPF-------NMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAG 159
Query: 329 -----QLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSP 383
LQ Q +S+ Q Q +QQQ Q QQQQPPP ++ HPQ A +P
Sbjct: 160 GIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQ-------HPQPAPQAP 212
Query: 384 SVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHT 443
S++ PL P P P P SQQ PP P + Q P+ H
Sbjct: 213 -------SQSQQQPLQPTPPQQP----------PPASQQ--PPAPTSQLQQA-PQPQQHQ 252
Query: 444 PQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGG 503
P Q+ + Q +SPPQ+ +PG G
Sbjct: 253 PHSHSQNQNQPSPTQQSSSPPQK------PSQSPGH-----------------------G 283
Query: 504 LPVPTSPNIQPSPAHETGQGIVH----ALTDLSSPGMTSGNGNSASSIAGTAPQNGENKP 559
LP P +P P+P + A +SS + GN+ SS+ G Q N
Sbjct: 284 LPSPLTP---PNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQ 340
Query: 560 PQAI 563
Q I
Sbjct: 341 GQII 344
Score = 34.7 bits (78), Expect = 0.39
Identities = 60/230 (26%), Positives = 87/230 (37%), Gaps = 22/230 (9%)
Query: 65 HRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQ-----ASLVSNRQ 119
H QP+ A Q Q A QQ ++QLQ QQ S N+
Sbjct: 204 HPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQP 263
Query: 120 GSTSGSNVSAQAPAQSSSINLAA---SPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSS 176
T S+ Q P+QS L + P QL+N + + AAA+ A ++
Sbjct: 264 SPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLA-SQAAAAAAAMSSIASSQAFG 322
Query: 177 PALTASQAQMYLRAQMLIFTPTATVATV--QPELGTGSPARPPTPA-QVQNLT---LRTQ 230
AL++ Q + Q++ + T+ P G S A T QVQ +T L
Sbjct: 323 NALSSLQG---VTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNA 379
Query: 231 QTPAAAASGPTPTQPVL--PSLALKPTPGGSQPLPTPAQSRNTAQASPAG 278
Q A PV+ + L P G Q L P+Q+ + QA+ G
Sbjct: 380 QGQIIATVIGNQILPVINTQGITLSPIKPGQQ-LHQPSQT-SVGQAASQG 427
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 73.6 bits (179), Expect = 8e-13
Identities = 116/492 (23%), Positives = 164/492 (33%), Gaps = 88/492 (17%)
Query: 72 AQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGSNVSAQA 131
A+Y +Q+Y Q+ L +A LSS+ ++S ++ + + S S VS
Sbjct: 503 AKYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQ 562
Query: 132 PAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMY---- 187
PA R+QS+ S+ S ++ L SS A S + Y
Sbjct: 563 PAGHV---------------RSQSIVSSVFSEAWKRGTQL-EESSKARMESMNRPYTSLV 606
Query: 188 --LRAQMLIFTP-TATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGP---- 240
L Q I TP TA+ + P PP P L +Q P+A ++ P
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666
Query: 241 -------------------TPTQPVLPSLALKP---------TPGGSQPLPTPAQSRNTA 272
PT PV+ S ++KP P P P P A
Sbjct: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA 726
Query: 273 QASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAV--AAHPLIAPAYAQL 330
Q PA P + P P + +++ P P+ AP Q
Sbjct: 727 QLKPAPCAPSLPQFSAPP---------PPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA 777
Query: 331 QPHQL--LPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQ 388
P L +P P+S V Q P PP + +P A P + +P V +
Sbjct: 778 PPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP-SPPTPPVPVP 836
Query: 389 PSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRF 448
P + P PL P ++ K SQ PPTP P
Sbjct: 837 PPTLPKQQSFCAKPPPSPLS-PVPSVVKQIASQFPPPPTP---------------PAMES 880
Query: 449 QHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPT 508
Q V + P SPP W+ P VP P P + ++V P PVP
Sbjct: 881 QPLKPVPANVAPQSPPAVKAKPKWQ---PSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA 937
Query: 509 SPNIQPSPAHET 520
P P A T
Sbjct: 938 PPPPPPPTASPT 949
Score = 57.4 bits (137), Expect = 6e-08
Identities = 97/409 (23%), Positives = 139/409 (33%), Gaps = 70/409 (17%)
Query: 196 TPTATVATVQPELGTGSPAR---PPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLAL 252
TP + +A ++P S + PP P ++ + TQ P P P+ P
Sbjct: 720 TPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP 779
Query: 253 KPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSR 312
KP P T + QA+P P + + +P + P S S
Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQP--------AFPASY---IPPSP 828
Query: 313 TVPAVAAHPLIAPAY----AQLQPHQLLPQPS-SKHLQPQFVIQQQPQPQQQQP------ 361
P V P P A+ P L P PS K + QF P + QP
Sbjct: 829 PTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPA 888
Query: 362 -PPQQSRPVLQAEPHPQLASV---SPSVALQPSSEAHAMPLGPVTPALPLQCP------- 410
QS P ++A+P Q +S+ SP P + P P +P +P P
Sbjct: 889 NVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP-VPAPPPPPPPTAS 947
Query: 411 ------------TANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQL 458
T+ PGG + PPTP G H +R S V
Sbjct: 948 PTPDKSGSPGKKTSKTSSPGGKKP--PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFT 1005
Query: 459 QPA---SPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGL----------- 504
PA SP ++ +P PG+ ++ P QQ V+A L
Sbjct: 1006 PPAESGSPSKETLPPPAAPPKPGKLNLSGVNL-PGVLQQGCVSAKAPVLSGRGKDSVVEF 1064
Query: 505 PVPTSPNIQPSPAHETGQGIVHALTDLSSPGMTSGNGNSASSIAGTAPQ 553
P P S + P P ET L + P + SGN + ++ PQ
Sbjct: 1065 PSPPSDSDFPPPPPETEL----PLPPIEIPAVFSGNTSPKVAVVNPQPQ 1109
Score = 41.2 bits (95), Expect = 0.004
Identities = 57/214 (26%), Positives = 84/214 (39%), Gaps = 39/214 (18%)
Query: 210 TGSPA-RPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTP---GGS---QPL 262
T SP + P P +N ++++ ++ A P P +P + SL K TP GS + L
Sbjct: 963 TSSPGGKKPPPTPQRNSSIKS----SSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETL 1018
Query: 263 PTPAQSRNTAQASPAGAK-PGIAD----SVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAV 317
P PA + + +G PG+ S P G G SV + P+
Sbjct: 1019 PPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFP--------SPPSD 1070
Query: 318 AAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQ-------QQPPPQQ----- 365
+ P P P +P S + P+ + PQPQQ + PPP +
Sbjct: 1071 SDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVN-PQPQQWSKMSVKKAPPPTRPKRND 1129
Query: 366 SRPVLQAE--PHPQLASVSPSVALQPSSEAHAMP 397
S + QAE P +A+V P V P S P
Sbjct: 1130 STRLTQAEISEQPTMATVVPQVPTSPKSSLSVQP 1163
>gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens]
Length = 681
Score = 73.6 bits (179), Expect = 8e-13
Identities = 34/66 (51%), Positives = 45/66 (68%)
Query: 788 PSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALK 847
P + TKW V+DV F+ L GC E FR Q IDG+ L LL E+HL++ M +KLGPALK
Sbjct: 537 PEDVTKWTVDDVCSFVGGLSGCGEYTRVFREQGIDGETLPLLTEEHLLTNMGLKLGPALK 596
Query: 848 IYARIS 853
I A+++
Sbjct: 597 IRAQVA 602
Score = 34.7 bits (78), Expect = 0.39
Identities = 89/392 (22%), Positives = 130/392 (33%), Gaps = 67/392 (17%)
Query: 134 QSSSINLAASPAAAQL---LNRAQSVNS------AAASGIAQQAVLLGNTSSPALTASQA 184
Q S+ + PA L L R+ ++S A S Q+A+LL P++
Sbjct: 132 QRGSLEIGLRPAGDLLGKRLGRSPRISSDCFSEKRARSESPQEALLLPRELGPSMAPED- 190
Query: 185 QMYLRAQMLIFTPTATVATVQPELGTGSPAR--------PPTPAQVQNLTLRTQQTPAAA 236
+ R + + +T Q G P+ PP +L Q+ AAA
Sbjct: 191 --HYRRLVSALSEASTFEDPQRLYHLGLPSHGEDPPWHDPPHHLPSHDLLRVRQEVAAAA 248
Query: 237 ASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDG 296
GP+ + LPS + G + AQ R GA P A S E
Sbjct: 249 LRGPSGLEAHLPS-----STAGQRRKQGLAQHRE-------GAAPAAAPSFSERELPQPP 296
Query: 297 NSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQP----QFVIQQ 352
P + P VA P + P + + P L P L P F QQ
Sbjct: 297 PLLSP----------QNAPHVALGPHLRPPFLGV-PSALCQTPGYGFLPPAQAEMFARQQ 345
Query: 353 QPQPQQQ----QPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQ 408
+ +Q + P R PQL ++P AL+P+ A + L
Sbjct: 346 ELLRKQNLARLELPADLLRQKELESARPQL--LAPETALRPNDGAEELQRRGALLVLNHG 403
Query: 409 CPTANLHKPGGSQQCHPPTPD-----TGPQNGHPEGVPHTPQRRFQHTSAVILQLQPA-- 461
P G PPTP P+ G P P + T A + +
Sbjct: 404 AAPLLALPPQGPPGSGPPTPSRDSARRAPRKGGPGPASARPSESKEMTGARLWAQDGSED 463
Query: 462 SPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQ 493
PP+ +D + A G + GP+P Q
Sbjct: 464 EPPKDSDGEDPETAAVGCR-------GPTPGQ 488
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 72.8 bits (177), Expect = 1e-12
Identities = 144/579 (24%), Positives = 198/579 (34%), Gaps = 108/579 (18%)
Query: 61 QQALHRQPSTAAQYLQQMYAAQQQHLM---LQTAALQQQHLSSAQLQSLAAVQQASLVSN 117
Q L QP + Q LQQ QQQ + Q QQQ L QLQ QQ
Sbjct: 3886 QPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQ 3945
Query: 118 RQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSP 177
+Q + Q Q LLN+++++ S QQ V LG P
Sbjct: 3946 QQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQ--QQQQVALG----P 3999
Query: 178 ALTASQAQMYLRAQMLIFTPTATVA-----TVQPELGTGSPARPPTPAQVQNLTLRTQQT 232
+ A Q + L PT + TV P + + + P T Q L T
Sbjct: 4000 GMPAKPLQHFSSPGAL--GPTLLLTGKEQNTVDPAVSSEATEGPSTH---QGGPLAIGTT 4054
Query: 233 PAAAASGPTPTQPVLPSLALKPTPGGSQPL---PTPAQSRNTAQASPAGAKPG-IADSVM 288
P + A+ P +P L G SQ L P P ++ Q P PG V
Sbjct: 4055 PESMATEPGEVKPSL--------SGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVS 4106
Query: 289 EPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSS---KHLQ 345
H G G+ GS G + + +VP + A P ++ L QP S L
Sbjct: 4107 LLHTAGGGSHGQLGS--GSSSEASSVPHLLAQPSVS----------LGDQPGSMTQNLLG 4154
Query: 346 PQFVIQQQPQPQQQQPPPQQSRPVLQA------------------------EPHPQLASV 381
PQ + ++P P P + PVLQ+ +PQL +
Sbjct: 4155 PQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHL 4214
Query: 382 SPSVALQPSS---EAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHP-----PTPDTGP- 432
SP Q + + V P Q P G C P P P TGP
Sbjct: 4215 SPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPL 4274
Query: 433 ----QNGHPEGVPHTP-QRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRS 487
P+G P P T V+ + P PP +P E P
Sbjct: 4275 QELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPS----------SPQEPKRPSQLP 4324
Query: 488 GPS---PHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSPGMTSGNGNSA 544
PS P + + P G P P P ++P P + A T L S G+ G +
Sbjct: 4325 SPSSQLPTEAQLPPTHP-GTPKPQGPTLEPPPGRVSPAAAQLADT-LFSKGL--GPWDPP 4380
Query: 545 SSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAE 583
++A T KP Q+ + P L V G V+ E ++
Sbjct: 4381 DNLAET------QKPEQSSLVPGHLDQV-NGQVVPEASQ 4412
Score = 54.3 bits (129), Expect = 5e-07
Identities = 71/306 (23%), Positives = 106/306 (34%), Gaps = 63/306 (20%)
Query: 216 PPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQAS 275
PP+PA +TP + +P P L P P P P SR +
Sbjct: 527 PPSPAL---------ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
Query: 276 PAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQL 335
+ P +S M P + SR P PL P + L
Sbjct: 578 ESPMSPPPEESPMSPPPEA----------------SRLFPPFEESPLSPPP----EESPL 617
Query: 336 LPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSP-SVALQPSSEAH 394
P P + L P P+ PPP++S P P+++ +SP V + S
Sbjct: 618 SPPPEASRLSP------PPEDSPMSPPPEES----PMSPPPEVSRLSPLPVVSRLSPPPE 667
Query: 395 AMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAV 454
PL P P + PT+ P + + PP P+ P + PE P +P ++
Sbjct: 668 ESPLSPP----PEESPTS---PPPEASRLSPP-PEDSPTSPPPEDSPASPPPE-DSLMSL 718
Query: 455 ILQLQPASP----PQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSP 510
L+ P P PQ C + ++P + E P P + P P P
Sbjct: 719 PLEESPLLPLPEEPQLCPRSEGPHLSPRPE---EPHLSPRPEE-------PHLSPQAEEP 768
Query: 511 NIQPSP 516
++ P P
Sbjct: 769 HLSPQP 774
Score = 51.6 bits (122), Expect = 3e-06
Identities = 87/354 (24%), Positives = 132/354 (37%), Gaps = 51/354 (14%)
Query: 212 SPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLA----LKPTPGGSQPLPTPAQ 267
SPA PP + +L L +++P P P +P L + L P P P P +
Sbjct: 705 SPASPPPEDSLMSLPL--EESPLL----PLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE 758
Query: 268 SRNTAQA-----SPAGAKPGIADSVMEPH--KKGDGNSSVPGSMEGRAGLSRTVP---AV 317
+ QA SP +P + EPH + +G P E P V
Sbjct: 759 PHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPV 818
Query: 318 AAHPLIAPA--YAQLQPHQ----LLPQPSSKHLQPQFVIQQQP-QPQQQQPPPQQSRPVL 370
P ++P + L P L P+P HL P+ +++ P P+ ++PP + +
Sbjct: 819 PEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE--LEKPPLSPRPEKPPEEPGQCPA 876
Query: 371 QAE----PHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPP 426
E P P S+SP + SE PL P+ LPL P+ +P S Q PP
Sbjct: 877 PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS-PSG---EPSLSPQLMPP 932
Query: 427 TPDTGPQN-----GHPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKS 481
P P + P + +P ++ P SP P ++P
Sbjct: 933 DPLPPPLSPIITAAAPPAL--SPLGELEYPFGAKGDSDPESP--LAAPILETPISP---- 984
Query: 482 VPETR-SGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSP 534
PE + P P I+ PG P SP + + + H+L +SP
Sbjct: 985 PPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSP 1038
Score = 50.8 bits (120), Expect = 5e-06
Identities = 75/313 (23%), Positives = 108/313 (34%), Gaps = 47/313 (15%)
Query: 207 ELGTGSP---ARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLP 263
EL T P +R P + ++ +++P + + P L P P S P
Sbjct: 560 ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP 619
Query: 264 TPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLI 323
P SR + + P +S M P + S +P +SR P PL
Sbjct: 620 PPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP-------VVSRLSPPPEESPLS 672
Query: 324 APAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSP 383
P + P P + L P P+ PPP+ S A P P+
Sbjct: 673 PPP----EESPTSPPPEASRLSP------PPEDSPTSPPPEDS----PASPPPE-----D 713
Query: 384 SVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHT 443
S+ P E+ +PL P P CP + G P P P+ PE +
Sbjct: 714 SLMSLPLEESPLLPL----PEEPQLCPRSE----GPHLSPRPEEPHLSPR---PEEPHLS 762
Query: 444 PQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGG 503
PQ H S QP P VP++ ++P + P P + T P
Sbjct: 763 PQAEEPHLSP-----QPEEPCLCAVPEE-PHLSP-QAEGPHLSPQPEELHLSPQTEEPHL 815
Query: 504 LPVPTSPNIQPSP 516
PVP P + P P
Sbjct: 816 SPVPEEPCLSPQP 828
Score = 49.3 bits (116), Expect = 2e-05
Identities = 89/373 (23%), Positives = 126/373 (33%), Gaps = 84/373 (22%)
Query: 233 PAAAASGPTPTQPVLPSLALKPTPGGS--------QPLPTPAQSRNTAQASPAGAKPGIA 284
PA + G P P+ L L P+ S PLP P TA A PA + G
Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL 957
Query: 285 DSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQ-----PHQLLPQP 339
+ KGD + P + P+ P A P +LP
Sbjct: 958 EYPFGA--KGDSDPESP-----------LAAPILETPISPPPEANCTDPEPVPPMILPPS 1004
Query: 340 SSKHLQPQFVIQQQPQPQQ------------QQPPPQQSRPVLQAEPHPQLASVSPSVAL 387
+ P I +P P Q PP Q S P L L+ + V +
Sbjct: 1005 PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGV 1064
Query: 388 QPSSEAHAMPLGPVT-PALPLQCPTAN--LHKPGGSQQCHPPTP------------DTGP 432
+E H M V+ P P P+A L P G C P+P DT P
Sbjct: 1065 SDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAP 1124
Query: 433 QNG--HPEGVPHTPQRRFQHTSAVILQLQPASP----PQQCVPDDWKEVAPGEKSVPETR 486
+G P P Q T + SP P++ P EV P K +T
Sbjct: 1125 LDGIDAPGSQPEPGQ-----TPGSLASELKGSPVLLDPEELAPVTPMEVYPECK---QTA 1176
Query: 487 SGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSPGMTSGNGNSASS 546
SP ++ P +P + P+P IV+ +++LS G++++S
Sbjct: 1177 GQGSPCEEQ---------EEPRAP-VAPTPPTLIKSDIVNEISNLS-------QGDASAS 1219
Query: 547 IAGTAPQNGENKP 559
G+ P G P
Sbjct: 1220 FPGSEPLLGSPDP 1232
Score = 48.5 bits (114), Expect = 3e-05
Identities = 98/429 (22%), Positives = 143/429 (33%), Gaps = 66/429 (15%)
Query: 164 IAQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPAR---PPTPA 220
+ QQ + L Q Q +L Q+ I VQ G + PP+
Sbjct: 3723 LQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSH 3782
Query: 221 Q---VQNLTLRTQQTPAAAASGPTPT---QPVLPSLALKPTPGGSQPLPTPAQSRNTAQA 274
Q VQ L+ + Q P GP Q P AL P Q L T ++ ++ Q
Sbjct: 3783 QGLLVQQLSPQPPQGPQGML-GPAQVAVLQQQHPG-ALGPQGPHRQVLMTQSRVLSSPQL 3840
Query: 275 SPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAP----AYAQL 330
+ G V ++ GSM G + L +++ + + P ++ + QL
Sbjct: 3841 AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQL 3900
Query: 331 QPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPS 390
Q Q L Q Q Q +QQQ Q QQQQ QQ + LQ + QL + Q
Sbjct: 3901 QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ 3960
Query: 391 SEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQH 450
+ + L + L P QQ Q G+P P + F
Sbjct: 3961 QQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQ---------QQVALGPGMPAKPLQHFSS 4011
Query: 451 TSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQ----------------- 493
A+ P + V P S E GPS HQ
Sbjct: 4012 PGAL-------GPTLLLTGKEQNTVDPAVSS--EATEGPSTHQGGPLAIGTTPESMATEP 4062
Query: 494 ----------QAIVTAMPGGLPVPTSPNIQPSPAHETGQ-----GIVHALTDLSSPGMTS 538
++ P P P+S +QP P GQ ++H S + S
Sbjct: 4063 GEVKPSLSGDSQLLLVQPQPQPQPSSLQLQP-PLRLPGQQQQQVSLLHTAGGGSHGQLGS 4121
Query: 539 GNGNSASSI 547
G+ + ASS+
Sbjct: 4122 GSSSEASSV 4130
Score = 47.8 bits (112), Expect = 4e-05
Identities = 76/288 (26%), Positives = 111/288 (38%), Gaps = 37/288 (12%)
Query: 204 VQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLP 263
V+P++ G R P+P Q T + + PAA + G +P + + T G+ P
Sbjct: 3118 VKPKVEEGG--RHPSPCQFTIATPKVEPAPAANSLG-LGLKPGQSMMGSRDTRMGTGPF- 3173
Query: 264 TPAQSRNTAQASPAGAKPGIADSVMEPHK-KGDGNSSVPGSMEGRAGLSRTVPA--VAAH 320
+ S +TA+ + GA G ++ P G G SS+ E +G + T+P A+
Sbjct: 3174 --SSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESG-ALTLPGGPAASG 3230
Query: 321 PLIAPAYAQLQPHQL------LPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEP 374
+ + L +L L + K LQ + + Q QP QQQ QQ +L A P
Sbjct: 3231 DELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSA-P 3289
Query: 375 HPQLASVSPSVALQPS----------SEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCH 424
P A P PS A A G P +P Q P L QQ
Sbjct: 3290 GPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHAL------QQRL 3343
Query: 425 PPTPDTGPQNGHPEGVPHTPQRRF--QHTSAVILQLQP--ASPPQQCV 468
P+ GH H Q Q +S +L +P PP C+
Sbjct: 3344 APSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCM 3391
Score = 43.1 bits (100), Expect = 0.001
Identities = 58/274 (21%), Positives = 94/274 (34%), Gaps = 36/274 (13%)
Query: 260 QPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAA 319
+P TP + + G G + M+P K G G+AG V
Sbjct: 376 EPGDTPTDEPDALYVACQGQPKGGHVTSMQP--KEPGPLQCEAKPLGKAG-------VQL 426
Query: 320 HPLIAPAYAQLQPHQLLPQPSSKHLQP---QFVIQQQPQPQQQQPPPQQ----------- 365
P + + P LLP P L P + P+ + PPP++
Sbjct: 427 EPQLEAPLNEEMP--LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALH 484
Query: 366 -SRPVLQA--EPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQ 422
SRP+ ++ P P+ + +SP P S PL P + P L P +
Sbjct: 485 LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP 544
Query: 423 CHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSV 482
PP ++ P + PE +P +P S + + PP++ E +
Sbjct: 545 LSPPFEES-PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603
Query: 483 PETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSP 516
E+ P P + + P P + + P P
Sbjct: 604 EESPLSPPPEESPL-------SPPPEASRLSPPP 630
Score = 41.6 bits (96), Expect = 0.003
Identities = 86/320 (26%), Positives = 116/320 (36%), Gaps = 76/320 (23%)
Query: 221 QVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAK 280
Q+Q TLR ++ AAAA+G P G++P +PA + + +P
Sbjct: 2694 QIQRNTLRQEKETAAAAAGAVG----------PPGSWGAEP-SSPAFEQLSRGQTPFAGT 2742
Query: 281 PGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPA-------VAAHPLIAPAYAQLQPH 333
+ V P K G PGS LSR P V + L+ + A +
Sbjct: 2743 QDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAF---Y 2799
Query: 334 QLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAE----PHPQL---ASVSPSVA 386
Q P P S LQ Q QQQ QQQ R + A P P+L A SP
Sbjct: 2800 QRAPYPGSLPLQQQ---QQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAG 2856
Query: 387 LQPSSEAHAMPL-GPVTPALPLQCPTANLHK---PGGSQQCHPPTPDTGPQNGHPEGVPH 442
+ P+ GP PA ++ N+ K PGG+ P P GP
Sbjct: 2857 ISTRLPGPGEPVPGPAGPAQFIEL-RHNVQKGLGPGGT-----PFPGQGP---------- 2900
Query: 443 TPQR-RFQHTSAVILQLQPAS---------PPQQCVPDDWKEVAPGEKSVPETRSG--PS 490
PQR RF S +L P PPQ+ P PE + P+
Sbjct: 2901 -PQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQK----------PSAPPAPELNNSLHPT 2949
Query: 491 PHQQAIVTAMPGGLPVPTSP 510
PH + +P GL + P
Sbjct: 2950 PHTKG--PTLPTGLELVNRP 2967
Score = 39.7 bits (91), Expect = 0.012
Identities = 72/316 (22%), Positives = 110/316 (34%), Gaps = 31/316 (9%)
Query: 165 AQQAVLLGNTSSPALTASQAQMYLRAQMLIF----TPTATVATVQPELGTGSPARPPTP- 219
A + +G+ ++PA ++ A +L+ +P + P++ P++ P
Sbjct: 2120 AAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGL 2179
Query: 220 AQVQNLTLRTQQTPAAAASGPTPT----QPVLPSLALKPTPGGSQPLPTPAQSRNTAQAS 275
A L R P P+PT QP P L PG QP + T +
Sbjct: 2180 APAYPLEPRFPTAPPTYPPYPSPTGAPAQP--PMLGASSRPGAGQP----GEFHTTPPGT 2233
Query: 276 PAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQL 335
P +P D ++P N +VP S G G + P ++ P A +
Sbjct: 2234 PRH-QPSTPDPFLKPRCPSLDNLAVPES-PGVGGGKASEPLLSPPPFGESRKALEVKKEE 2291
Query: 336 LPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRP-VLQAEPHPQLASV---SPSVALQPSS 391
L S + P P + P V +A P+ + V SP + L+P
Sbjct: 2292 LGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE 2351
Query: 392 EAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDT-GPQNGHPEGVPHTPQRRFQH 450
A L P P+ P ++ +PG + P T PQ PE P R
Sbjct: 2352 PPPAQALAPSPPSHP------DIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPS 2405
Query: 451 TSAVILQLQPASPPQQ 466
PASP Q
Sbjct: 2406 DP---FSRVPASPQSQ 2418
Score = 37.4 bits (85), Expect = 0.060
Identities = 28/72 (38%), Positives = 34/72 (47%), Gaps = 9/72 (12%)
Query: 34 SGGSGRPTGPQISVYSGI-------PDRQTVQVIQQALHRQPSTAAQYLQQMYA--AQQQ 84
SGG+G GP + G PD + +Q Q L +Q AQ LQQ QQQ
Sbjct: 3686 SGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQ 3745
Query: 85 HLMLQTAALQQQ 96
HL+ Q A QQQ
Sbjct: 3746 HLLGQVAIQQQQ 3757
Score = 34.7 bits (78), Expect = 0.39
Identities = 62/244 (25%), Positives = 77/244 (31%), Gaps = 49/244 (20%)
Query: 221 QVQNLTLRTQQTPAAAASGPTPTQPVLPSLA--LKPTPGGSQPLPTPAQSRNTAQASPAG 278
Q Q + QQ A A P+ + +L L L P G P P + +P G
Sbjct: 3602 QQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGG 3661
Query: 279 -AKPG----------IADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAY 327
A PG +A + H G GS+ G +G P A + P
Sbjct: 3662 MALPGQPGGPFLNTALAQQQQQQHSGG------AGSLAGPSG--GFFPGNLALRSLGPDS 3713
Query: 328 AQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQ-------PPPQQSRPVLQAEPHPQLAS 380
LQ QL Q L + QQQ Q QQQ QQ P +Q Q
Sbjct: 3714 RLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTN---QALG 3770
Query: 381 VSPSVALQPSSEAHAM--------PLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGP 432
P + PSS + P GP P Q PG GP
Sbjct: 3771 PKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGA----------LGP 3820
Query: 433 QNGH 436
Q H
Sbjct: 3821 QGPH 3824
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 68.9 bits (167), Expect = 2e-11
Identities = 90/340 (26%), Positives = 133/340 (39%), Gaps = 62/340 (18%)
Query: 213 PARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLP--------- 263
PA+ P P + + Q P A + P PT + +P G +QP P
Sbjct: 330 PAKLPEPVKASEAAAKKTQ-PKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPAL 388
Query: 264 TPAQSRNTAQASPAGA----KPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRT---VPA 316
TP + R T Q P A +PG+ SV +P + + +P + + T P+
Sbjct: 389 TP-RKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPS 447
Query: 317 VAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHP 376
A L PA AQ P +H Q F+ QQQ QQQQPPP Q +P
Sbjct: 448 TQAQGL--PAQAQATP---------QHQQQLFLKQQQ---QQQQPPPAQQQPA-GTFYQQ 492
Query: 377 QLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGH 436
Q A A+ P+++ A+ PV GGSQQ QN +
Sbjct: 493 QQAQTQQFQAVHPATQQPAIAQFPVV-------------SQGGSQQ-------QLMQNFY 532
Query: 437 PEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSG--PSPHQQ 494
+ Q++ Q + + Q Q + QQ +A G++ P+ + P+P Q+
Sbjct: 533 QQQQQQQQQQQQQQLATALHQQQLMT--QQAALQQKPTMAAGQQPQPQPAAAPQPAPAQE 590
Query: 495 AIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSP 534
+ A PV P +Q +P V +LT SSP
Sbjct: 591 PAIQA-----PVRQQPKVQTTPPPAVQGQKVGSLTPPSSP 625
Score = 48.1 bits (113), Expect = 3e-05
Identities = 62/243 (25%), Positives = 86/243 (35%), Gaps = 36/243 (14%)
Query: 172 GNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQ 231
G+++ P L AS Q P A + P+ P PPTP Q + + Q
Sbjct: 404 GSSNQPGLLASVPQP---------KPQAPPSQPLPQTQAKQPQAPPTPQQTP--STQAQG 452
Query: 232 TPAAAASGPTPTQPVL---PSLALKPTPGGSQPLPT-----PAQSRNTAQASPAGAKPGI 283
PA A + P Q + +P P QP T AQ++ PA +P I
Sbjct: 453 LPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQPAI 512
Query: 284 ADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKH 343
A + S M+ + +A A L QL+ Q ++
Sbjct: 513 AQFPVVSQ-----GGSQQQLMQNFYQQQQQQQQQQQQQQLATA---LHQQQLMTQQAALQ 564
Query: 344 LQPQFVIQQQPQPQ---QQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGP 400
+P QQPQPQ QP P Q P +QA Q P V P +G
Sbjct: 565 QKPTMAAGQQPQPQPAAAPQPAPAQ-EPAIQAPVRQQ-----PKVQTTPPPAVQGQKVGS 618
Query: 401 VTP 403
+TP
Sbjct: 619 LTP 621
Score = 39.3 bits (90), Expect = 0.016
Identities = 40/162 (24%), Positives = 58/162 (35%), Gaps = 19/162 (11%)
Query: 324 APAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSP 383
+P A+L + ++K QP+ + + P+Q Q +P+P + + P
Sbjct: 327 SPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQP 386
Query: 384 SVALQPSSEAHAMP-------------LGPVTPALPLQCPTANLHKPGGSQQCHPPTPDT 430
AL P A P L V P P+ L + Q PPTP
Sbjct: 387 --ALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQ 444
Query: 431 GPQNGHPEGVPHTPQRRFQHTSAVIL---QLQPASPPQQCVP 469
P +G+P Q QH + L Q Q PP Q P
Sbjct: 445 TPST-QAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQP 485
Score = 33.9 bits (76), Expect = 0.66
Identities = 45/191 (23%), Positives = 64/191 (33%), Gaps = 21/191 (10%)
Query: 54 RQTVQVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQAS 113
+QT Q L Q Q+ QQ++ QQQ Q QQQ + Q A QQ
Sbjct: 443 QQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQ-QQQPPPAQQQPAGTFYQQQQAQTQQFQ 501
Query: 114 LVSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGN 173
V + + Q PA +A P +Q ++ Q + + QQ
Sbjct: 502 AV----------HPATQQPA------IAQFPVVSQGGSQQQLMQNFYQQQQQQQQ----Q 541
Query: 174 TSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTP 233
L + Q L Q T+A Q + A P PAQ + +Q P
Sbjct: 542 QQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQP 601
Query: 234 AAAASGPTPTQ 244
+ P Q
Sbjct: 602 KVQTTPPPAVQ 612
Score = 30.4 bits (67), Expect = 7.3
Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 7/77 (9%)
Query: 43 PQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAA---QQQHLMLQTAALQQQHLS 99
P I+ + + + Q + Q ++Q Q QQ A QQ LM Q AALQQ+
Sbjct: 510 PAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTM 569
Query: 100 SA----QLQSLAAVQQA 112
+A Q Q AA Q A
Sbjct: 570 AAGQQPQPQPAAAPQPA 586
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 67.8 bits (164), Expect = 4e-11
Identities = 127/503 (25%), Positives = 170/503 (33%), Gaps = 91/503 (18%)
Query: 100 SAQLQSLAAVQ--QASLVSNRQGSTSGSNVSAQAPAQSSSI------NLAASPAAAQLLN 151
SA + S A +Q Q +L +GS + PA + + P+A +LN
Sbjct: 538 SAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLN 597
Query: 152 R----AQSVNSAAASGIAQ---------QAVLLGNTSSP-ALTASQAQMYLRAQMLIFTP 197
Q AAA+G A QA +T P L QAQ +A
Sbjct: 598 TPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAA 657
Query: 198 TATVATVQPELGTGSP------ARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLA 251
T QP G S +PP+ LT + Q P P L+
Sbjct: 658 PPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLS 717
Query: 252 LKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHK----------KGDGNSSVP 301
+ + S P P + T A AG P DS P KG G SS P
Sbjct: 718 VPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSP 777
Query: 302 GSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQ------------FV 349
S+ +A L + + HP P+ +P + PS L P FV
Sbjct: 778 -SLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFV 836
Query: 350 IQQQ--------------PQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHA 395
IQ Q P P Q PQ P P P L S S A+ SSE +
Sbjct: 837 IQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSS 896
Query: 396 MPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVI 455
P LQ P P P P T P P P R FQ +
Sbjct: 897 RLPAPTPSDFQLQFP------PSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
Query: 456 LQLQPASPPQQCVPDDWKEV---------APGEKSVPETRS--GP--SPHQQAIVTAM-P 501
PA P + + + + +V A G + P+T + GP SP +V+ P
Sbjct: 951 ----PALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAP 1006
Query: 502 GGLPVPTSPNIQPSPAHETGQGI 524
G PT+P+ P+PA G+
Sbjct: 1007 SG--TPTAPSHAPAPAPMAATGL 1027
Score = 67.4 bits (163), Expect = 5e-11
Identities = 147/601 (24%), Positives = 201/601 (33%), Gaps = 126/601 (20%)
Query: 14 ACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALHR-----QP 68
+ A ++T +S G ++S +G P+G ++V G+ V LHR QP
Sbjct: 294 SAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQP 353
Query: 69 STAAQYLQQMY---------AAQQQHLMLQTAALQQQHLSSAQLQSLAA--VQQASLVSN 117
A ++Y A + + AL QQ + L +AA Q ++S
Sbjct: 354 KPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSG 413
Query: 118 RQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSV---NSAAASGIAQQAVLLGNT 174
+NV Q PA ++ AA P L++ SV N ++ I Q +L G
Sbjct: 414 FPAPALQANVFKQPPATTTG---AAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQN 470
Query: 175 -----SSPALTASQAQMYLRAQM---------------LIFTPTATVATVQPELGTGSPA 214
+PA+ Q L A + LI P T + L G
Sbjct: 471 QFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVL 530
Query: 215 RP-----------PTPAQVQNLTLRTQQTPAAAASGPTPTQP---------VLPSLALKP 254
P P QV L AA S PT +QP VL + L P
Sbjct: 531 APHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPP 590
Query: 255 -------TPGGSQPLPTPAQSRNTA----------QASPAGAKPGIADSVMEPHKKGDGN 297
TP G TPA + A QA PA + P + + +P +
Sbjct: 591 SAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTP-LPLGLQQPQAQQPPQ 649
Query: 298 SSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQ---- 353
+ P P A P +P A +L QP S P ++ Q
Sbjct: 650 APTP---------QAAAPPQATTPQPSPGLASSPEKIVLGQPPS--ATPTAILTQDSLQM 698
Query: 354 --PQPQQQQP----PPQQSRP--VLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPAL 405
PQ + QQP P S P V+ + P P + P+ A + A P P + A
Sbjct: 699 FLPQERSQQPLSAEGPHLSVPASVIVSAPPP---AQDPAPATPVAKGAGLGPQAPDSQAS 755
Query: 406 PLQCP----TANLHKPGGSQQCHPPTPDTGP-------QNGHPEGVPHTPQRRFQHTSAV 454
P P A L PG S P P P + HP P P R Q S
Sbjct: 756 PAPAPQIPAAAPLKGPGPSSS--PSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSR- 812
Query: 455 ILQLQPASPP-QQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQ 513
P+ PP C P PG + P P TA PG P P Q
Sbjct: 813 ----PPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTA-PGPPQPPLRPQSQ 867
Query: 514 P 514
P
Sbjct: 868 P 868
Score = 31.6 bits (70), Expect = 3.3
Identities = 30/95 (31%), Positives = 35/95 (36%), Gaps = 9/95 (9%)
Query: 197 PTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPT- 255
P AT+ +P P PP P N T+ PAA P T P P L L+ T
Sbjct: 1336 PPATLKVAEPP---PRPPPPPPPTGQMNGTV-DHPPPAAPERKPLGTAPHCPRLPLRKTY 1391
Query: 256 ----PGGSQPLPTPAQSRNTAQASPAGAKPGIADS 286
G P TPA +P AK A S
Sbjct: 1392 RENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATS 1426
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 67.4 bits (163), Expect = 5e-11
Identities = 100/429 (23%), Positives = 142/429 (33%), Gaps = 65/429 (15%)
Query: 115 VSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNT 174
++ R G G+ + AP + + P A+ RA + + ++ G T
Sbjct: 58 LAERAGGIGGATIPESAPRAGPT--RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115
Query: 175 SSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGS--PARPPTPAQVQNLTLRTQQT 232
L Q + + A+ + AT A + L G+ PTP R +
Sbjct: 116 RPGPL--GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 173
Query: 233 PAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAK-PGIADSVMEPH 291
P P PS +P G + + A +T + SPA + P + P
Sbjct: 174 AGTEVGLPRPA----PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 229
Query: 292 KKGDGNSSVPGSMEGRAGLS-RTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVI 350
+ +S+ P S R+G S R P AHP QP K LQ
Sbjct: 230 SRSLSSSATPLSSPARSGPSARGTPRAPAHP---------------SQPKPKGLQAL--- 271
Query: 351 QQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCP 410
+P Q PP + + P L LA+ SPS PS+ L P PA P
Sbjct: 272 ----RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL-PSPPATPPSQA 326
Query: 411 TANLHKPGGSQQCHP--PTPDTGPQNGHPEGVP-----------------------HTPQ 445
T +L P Q H P+P P P P TP
Sbjct: 327 TTSLGSP-TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385
Query: 446 RRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLP 505
+ + AV L P SPP P + + P +P QA + L
Sbjct: 386 PQAPNALAVHLLQAPFSPP----PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441
Query: 506 VPTSPNIQP 514
VP SP P
Sbjct: 442 VPPSPPASP 450
Score = 57.8 bits (138), Expect = 4e-08
Identities = 136/619 (21%), Positives = 206/619 (33%), Gaps = 116/619 (18%)
Query: 8 PHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALHRQ 67
P S S+ + ST+ S ++ S+ GG RP +S + +
Sbjct: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS--------SSATPLSSPARSG 247
Query: 68 PSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGSNV 127
PS + H S + + L A++ + R+ +
Sbjct: 248 PSA------------------RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 289
Query: 128 SAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMY 187
+ +P + S + SP+A L Q++ S A+ +Q LG SP L A+ + +
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSL---QTLPSPPATPPSQATTSLG---SPTLQATHSFLP 343
Query: 188 LRAQMLIFT--PTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAA-------AAS 238
+ T P A A P L +P PP + L + Q P A A
Sbjct: 344 SPPLSPLATPPPQAPPALALPPL--QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401
Query: 239 GPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPG-IADSVMEPHKKGDGN 297
P P+ PV + +P S P+Q+ + A P P A M P
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461
Query: 298 SSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQ 357
+ P L+ +A P AP P Q LP P + F Q P
Sbjct: 462 APPP--------LAAPPLQLAKPPPQAPPALATPPLQALPSPPA-----SFPGQAPFSPS 508
Query: 358 QQQP------PPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPT 411
P PP Q+ PVL A L V PS P+ +A P P P + P
Sbjct: 509 ASLPMSPLATPPPQAPPVLAA----PLLQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPR 563
Query: 412 ANLHKPGGSQQCHPPTPDTGPQN--------GHPEGVPHTPQRRFQHTSAVILQLQPASP 463
L G PP P P + GH TP+ + S + P
Sbjct: 564 LTLALAPGP----PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 619
Query: 464 PQ----QCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAH- 518
P C P W GP+P + G P+P P P A
Sbjct: 620 PDAELAACHPAAWSR-------------GPAP---PLAFRGAPGAPLPWPPATGPGSADG 663
Query: 519 ----------ETGQGIVHALTDLSSPGMTSGNGNSASSIAGTAPQNGE----NKPPQAIV 564
E+ AL SPG TSG +A + AG + ++ + + P +
Sbjct: 664 LCTIYETEGPESATPAPGALDPGPSPG-TSGGKAAAGAGAGASSRSPKQARLGELPLGAL 722
Query: 565 KPQILTHVIEGFVIQEGAE 583
+ ++ H++ ++ AE
Sbjct: 723 QASVVQHLLSRTLLLAAAE 741
>gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3
[Homo sapiens]
Length = 837
Score = 67.0 bits (162), Expect = 7e-11
Identities = 122/471 (25%), Positives = 165/471 (35%), Gaps = 88/471 (18%)
Query: 73 QYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGSNVSAQAP 132
Q QQ+ QQQ LQ LQQQ L QL L + Q S + Q P
Sbjct: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
Query: 133 AQ---------SSSINLAASPAAAQLLNRAQSVNSAA-------ASGIAQQAVLLGN--- 173
Q S+S+ + A LL + Q ++ A +G+ LGN
Sbjct: 65 QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRG 124
Query: 174 --TSSPALTASQ--AQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRT 229
+SP L A + F P AT Q LG P P+Q NL+ R
Sbjct: 125 YGMASPGLAAPSLTPPQLATPNLQQFFPQ---ATRQSLLGPPPVGVPMNPSQF-NLSGRN 180
Query: 230 QQTPAAAASGPTPTQPVLPSLALKPTPGGS-------------QPLP-----------TP 265
Q A +S TP + +P P GS Q LP TP
Sbjct: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240
Query: 266 AQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAP 325
A +AS AK + S K+ G V + R TVP P + P
Sbjct: 241 APEPEPCEASELPAK-RLRSSEEPTEKEPPGQLQVKAQPQAR----MTVPKQTQTPDLLP 295
Query: 326 AYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLAS---VS 382
+ Q+LP+ + LQ Q +Q Q QP+ Q +P LQ + Q + V
Sbjct: 296 EALEA---QVLPRFQPRVLQVQAQVQSQTQPRIPS-TDTQVQPKLQKQAQTQTSPEHLVL 351
Query: 383 PSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDT--GPQNGHPEGV 440
+QP + A P V P + Q +P Q HPP + P+ H +
Sbjct: 352 QQKQVQPQLQQEAEPQKQVQPQVHTQA------QPSVQPQEHPPAQVSVQPPEQTHEQ-- 403
Query: 441 PHTPQRRFQHTSAVILQLQPASPP---QQC---VPDDWKEVAPG-EKSVPE 484
HT + L P P C +P D E G EK++PE
Sbjct: 404 --------PHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPE 446
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 65.9 bits (159), Expect = 2e-10
Identities = 109/422 (25%), Positives = 155/422 (36%), Gaps = 61/422 (14%)
Query: 131 APAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSS--PALTASQAQMYL 188
AP S ASP+A+ L + S ++S +LL TSS P L ++ A
Sbjct: 1487 APGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAP--- 1543
Query: 189 RAQMLIFTPTATVATVQPELGTGSPARPP--TPAQVQNLTLRTQQTPAAAAS----GPTP 242
A + P + +A+ P +PA+ PA + L T P AA P+P
Sbjct: 1544 -ACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSP 1602
Query: 243 TQPVLPSLALKPTPGGS-------QPLPTPAQSRNTAQASPAGAKPGIADS-VMEPHKKG 294
P+ P L P+PG + P+P A S +T S A A P A + V+ P
Sbjct: 1603 APPLAPLPVLAPSPGAAPVLASSQTPVPVMAPS-STPGTSLASASPVPAPTPVLAP---S 1658
Query: 295 DGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQP 354
+ +P + + +A P +AP P Q L + Q P
Sbjct: 1659 STQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGN--------PQGP 1710
Query: 355 QPQQQQPPPQQSRPVLQAEPHP-QLASVSPSVALQPS---SEAHAMPLGPVTPALPLQCP 410
P Q P P P Q S++P L P+ S A A PL P +P P
Sbjct: 1711 FPTQ----TLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAH 1766
Query: 411 T---------ANLHKPGGSQQ---CHPPTPDTGPQNGHPEGV-PHTPQRRFQHTSAVILQ 457
T A+L P Q P P GP + P + Q S++++
Sbjct: 1767 TLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVS 1826
Query: 458 LQPASPPQQCVPDDWKEVAPGEKSVPET---RSGPSPHQQAIVTAMPGGLPVPTSPNIQP 514
A+P +P P K P+T RSGP P + T+ G P P
Sbjct: 1827 ASGAAP----LPVTMVSRLPVSKDEPDTLTLRSGP-PSPPSTATSFGGPRPRRQPPPPPR 1881
Query: 515 SP 516
SP
Sbjct: 1882 SP 1883
Score = 57.0 bits (136), Expect = 7e-08
Identities = 116/472 (24%), Positives = 157/472 (33%), Gaps = 86/472 (18%)
Query: 141 AASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTAT 200
A++P AA L +S + + L G SSP + + + + P ++
Sbjct: 1387 ASAPGAAPL---------TISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSS 1437
Query: 201 VATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQ 260
+ +PA P + + PA S P PV+P+ PG
Sbjct: 1438 SLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPA-----APGPPS 1492
Query: 261 PLPTPAQSRNTAQASPAGAKPGIADSVMEPHK--KGDGNSSVPGSMEGRAGLSRTVPAVA 318
P+ A +A P ++ S H +S VP GL+ TV A A
Sbjct: 1493 LAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVP-------GLNSTV-APA 1544
Query: 319 AHPLIAPAYAQLQPHQLLPQP-------------SSKHLQPQFVIQQQPQPQQQQP---P 362
P++ PA A P P P +S+ L PQ P P
Sbjct: 1545 CSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAP 1604
Query: 363 PQQSRPVL----------------------QAEPHPQLASVSPSVA----LQPSSEAHAM 396
P PVL + P LAS SP A L PSS +
Sbjct: 1605 PLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTML 1664
Query: 397 PLGPVTPALPLQCPTANLHKP-------GGSQQCHPPTPDTG-PQNGHP-EGVPHTPQRR 447
P PV LP T L GGS + TG PQ P + + TP
Sbjct: 1665 P-APVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASS 1723
Query: 448 FQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSP-HQQAIVTA-MPGGLP 505
T A L L P P P +AP P + GP+P H + A L
Sbjct: 1724 LVPTPAQTLSLAPGPP---LGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLL 1780
Query: 506 VPTS-PNIQPSPAHETGQGIVHALTDLSSPGMTSGNGNSASSI----AGTAP 552
P S + SPA G A T +P T + ASS+ +G AP
Sbjct: 1781 APASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAP 1832
Score = 53.5 bits (127), Expect = 8e-07
Identities = 97/435 (22%), Positives = 156/435 (35%), Gaps = 59/435 (13%)
Query: 10 TSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALHRQPS 69
+ +S A++ T G +++ ++S + G P S G+ + L +
Sbjct: 1496 SGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGL-NSTVAPACSPVLVPASA 1554
Query: 70 TAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGSNVSA 129
A+ + A Q +L A+ Q L++ L +AA Q A L +
Sbjct: 1555 LASPFPSAPNPAPAQASLLAPASSASQALATP-LAPMAAPQTAILAPS------------ 1601
Query: 130 QAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMYLR 189
AP + LA SP AA +L +Q+ ++ +S+P + + A
Sbjct: 1602 PAPPLAPLPVLAPSPGAAPVLASSQT-----------PVPVMAPSSTPGTSLASA----- 1645
Query: 190 AQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPT------ 243
+ + TP ++ Q L P+ P+PA Q L L P S P+ T
Sbjct: 1646 SPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTG 1705
Query: 244 --QPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVP 301
Q P+ L TP S +PTPAQ+ + A P G ++ + P P
Sbjct: 1706 NPQGPFPTQTLSLTPASSL-VPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAP 1764
Query: 302 GSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQP 361
A PA ++ L+APA Q P P+ L P P Q
Sbjct: 1765 ------AHTLTLAPASSSASLLAPASVQTLTLSPAPVPT---LGPAAAQTLALAPASTQS 1815
Query: 362 PPQQSRPVL----QAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKP 417
P Q+ ++ A P P + VS + + + GP +P P+
Sbjct: 1816 PASQASSLVVSASGAAPLP-VTMVSRLPVSKDEPDTLTLRSGPPSP------PSTATSFG 1868
Query: 418 GGSQQCHPPTPDTGP 432
G + PP P P
Sbjct: 1869 GPRPRRQPPPPPRSP 1883
Score = 38.5 bits (88), Expect = 0.027
Identities = 63/266 (23%), Positives = 92/266 (34%), Gaps = 70/266 (26%)
Query: 209 GTGSPARPPTPAQVQNL--------------TLRTQQTPAAAASGP----TPTQPVLPSL 250
GTG P +PP P ++ L R QQ AA+ P T P PS+
Sbjct: 2734 GTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSV 2793
Query: 251 ALKPTPGGSQP------------LPTPAQS-----RNTAQASPAGAKPGIADSVM----- 288
P S P LPTP Q R+ G P D +
Sbjct: 2794 RSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITP 2853
Query: 289 --------EPHKK-------GDGNSSVPGS-MEGRAGLSRTVPA----VAAHPLIAPAYA 328
P KK G G P S ++G+ + VP + A P++ P
Sbjct: 2854 PAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLI 2913
Query: 329 QLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQ 388
P L PQP + P ++ + ++ +PP + P+ P ++ + +
Sbjct: 2914 P-GPQPLGPQPVHR---PNPLLSPVEKRRRGRPPKARDLPI----PGTISSAGDGNSESR 2965
Query: 389 PSSEAHAMPLGPVTPALPLQCPTANL 414
H PL P+ P L CPTA +
Sbjct: 2966 TQPPPHPSPLTPLPPL--LVCPTATV 2989
Score = 37.7 bits (86), Expect = 0.046
Identities = 59/239 (24%), Positives = 85/239 (35%), Gaps = 29/239 (12%)
Query: 314 VPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQ-- 371
VP A P+ AP + P +LP P P P PPP + P Q
Sbjct: 2460 VPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTC 2519
Query: 372 -AEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDT 430
P L PSV + S+ +PLG + P L C A L P + + +T
Sbjct: 2520 LVTPSSPLLLGPPSVPI--SASVTNLPLG-LRPEAEL-CAQA-LASPESLELASVASSET 2574
Query: 431 G------PQNGHPEGVPHTPQRRFQHTSAVILQLQPASP----PQQCVPDDWKEVAPGEK 480
P++ P V P S L L P++P +P+ ++ AP
Sbjct: 2575 SSLSLVPPKDLLPVAVEILP------VSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSA 2628
Query: 481 SVPETRSGPSPHQQAIVTAMPGGLPVPTS-----PNIQPSPAHETGQGIVHALTDLSSP 534
P + + + GL +P S P +P A T + + A T SSP
Sbjct: 2629 EGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSP 2687
Score = 37.4 bits (85), Expect = 0.060
Identities = 77/339 (22%), Positives = 110/339 (32%), Gaps = 45/339 (13%)
Query: 197 PTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKP-- 254
P A T T + P P + + A SG + L SLA +P
Sbjct: 1140 PPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVA 1199
Query: 255 TPGGSQPLP----------TPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSM 304
GGS+PL T AQ R A P + + V S
Sbjct: 1200 NAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLV---------------SA 1244
Query: 305 EGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQ 364
G+ L VA +AP P +LP S+ P P Q PP
Sbjct: 1245 GGQHHLISQPAHVALIQAVAPTPGP-TPVSVLPS-STPSTTPAPTGLSLPLAANQVPPTM 1302
Query: 365 QS-----RPVLQAEPHPQLASVSP-SVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPG 418
+ + V++ P L V P + A +P S L P P + PT L
Sbjct: 1303 VNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTL---- 1358
Query: 419 GSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPG 478
G+ + PTP + H+P ++ L +SP VP A
Sbjct: 1359 GTARAPMPTPTLVRP---LLKLVHSPSPEVSASAPGAAPLTISSPLH--VPSSLPGPASS 1413
Query: 479 EKSVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSPA 517
+P + SP + + LP+ + P P+PA
Sbjct: 1414 PMPIPNSSPLASPVSSTVSVPLSSSLPI-SVPTTLPAPA 1451
Score = 31.2 bits (69), Expect = 4.3
Identities = 76/325 (23%), Positives = 107/325 (32%), Gaps = 61/325 (18%)
Query: 214 ARPPTPAQVQNLTLRTQQTPAAAASGPTP-------TQPVLPSLALKPTPGGSQPLPTPA 266
+RPP P + L + P P+P ++P P+L+LKPTP P P
Sbjct: 1064 SRPPGPVLLPPLQPNSGSLPQVL---PSPLGVLSGTSRPPTPTLSLKPTP------PAP- 1113
Query: 267 QSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPA 326
+ SP A P + S+++P G + P + + + T A P PA
Sbjct: 1114 -----VRLSP--APPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAV-PAPTPA 1165
Query: 327 YAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQA-EPHPQLASVSPSV 385
P +L+ P + P + Q RPV A P + +
Sbjct: 1166 -----PQRLILSPDMQARLPSGEVVSIGQLAS-----LAQRPVANAGGSKPLTFQIQGNK 1215
Query: 386 ALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGG-----SQQCH-------PPTPDTGPQ 433
++ + +G PLQ +L GG SQ H PTP P
Sbjct: 1216 LTLTGAQVRQLAVG---QPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPV 1272
Query: 434 NGHPEGVPH-TPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAP--GEKSVPETRSGPS 490
+ P P TP Q+ P V AP G VP P
Sbjct: 1273 SVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPR 1332
Query: 491 PHQQAI-------VTAMPGGLPVPT 508
P + T PG LP PT
Sbjct: 1333 PPSSGLPAVLNPRPTLTPGRLPTPT 1357
>gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens]
Length = 660
Score = 65.5 bits (158), Expect = 2e-10
Identities = 34/68 (50%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
Query: 790 EPTKWNVEDVYEFIRSL-PGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKI 848
+P+ W VEDV +F+R P A+ FR EIDG+ALLLL+ D +M M +KLGPALK+
Sbjct: 589 DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
Query: 849 YARISMLK 856
I LK
Sbjct: 649 SYHIDRLK 656
Score = 32.3 bits (72), Expect = 1.9
Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 16/129 (12%)
Query: 263 PTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPL 322
P PA NT + S + + + +P ++G PG GR T + +HP+
Sbjct: 245 PYPASDVNTEKPSIHSSTKTVLEH--QPGQRG----RKPGKKRGR-----TPKTLISHPI 293
Query: 323 IAPAYAQLQ---PHQLLPQPSSKHLQPQFVIQQQP-QPQQQQPPPQQSRPVLQAEPHPQL 378
AP+ P + P+P SK +P+ ++ P P P P S A P
Sbjct: 294 SAPSKTAEPLKFPKKRGPKPGSKR-KPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSS 352
Query: 379 ASVSPSVAL 387
A +P+V +
Sbjct: 353 AMQAPTVCI 361
>gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens]
Length = 591
Score = 65.5 bits (158), Expect = 2e-10
Identities = 34/68 (50%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
Query: 790 EPTKWNVEDVYEFIRSL-PGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKI 848
+P+ W VEDV +F+R P A+ FR EIDG+ALLLL+ D +M M +KLGPALK+
Sbjct: 520 DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 579
Query: 849 YARISMLK 856
I LK
Sbjct: 580 SYHIDRLK 587
Score = 32.3 bits (72), Expect = 1.9
Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 16/129 (12%)
Query: 263 PTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPL 322
P PA NT + S + + + +P ++G PG GR T + +HP+
Sbjct: 198 PYPASDVNTEKPSIHSSTKTVLEH--QPGQRG----RKPGKKRGR-----TPKTLISHPI 246
Query: 323 IAPAYAQLQ---PHQLLPQPSSKHLQPQFVIQQQP-QPQQQQPPPQQSRPVLQAEPHPQL 378
AP+ P + P+P SK +P+ ++ P P P P S A P
Sbjct: 247 SAPSKTAEPLKFPKKRGPKPGSKR-KPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSS 305
Query: 379 ASVSPSVAL 387
A +P+V +
Sbjct: 306 AMQAPTVCI 314
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 64.3 bits (155), Expect = 5e-10
Identities = 129/554 (23%), Positives = 191/554 (34%), Gaps = 70/554 (12%)
Query: 112 ASLVSNRQGSTSGSNVSAQA-----PAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQ 166
A +S+ +G T GS +A A P+ S+S + ++S A Q +AA G
Sbjct: 228 AYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTP 287
Query: 167 QAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLT 226
Q + + S A+ Y P + + G G + P Q
Sbjct: 288 QPTATPTLNQLLTSPSSARGYQGY------PGGDYSGGPQDGGAG---KGPADMASQCWG 338
Query: 227 LRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLP-TPAQSRNTAQASPAGAKPGIAD 285
AAAASG + ++ + GG QPL TP S Q +P
Sbjct: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGT 398
Query: 286 SVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQ-----LQPHQLLPQPS 340
+ P+ + G S P G G +P+ AQ L Q +P
Sbjct: 399 N---PYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYG 455
Query: 341 SKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLG- 399
+ Q P QQ P PQQ +P +P Q PS QP S+ +
Sbjct: 456 QQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQ 515
Query: 400 PVTPALPLQCPTANLHKPGGSQQC----HPPT--PDTGPQNGHP-------EGVPHT--- 443
P P Q P P SQQ HP + P + PQ P + P T
Sbjct: 516 PPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQ 575
Query: 444 ----PQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTA 499
PQ + Q + Q PPQ+ D + A S+ ++ G ++ +
Sbjct: 576 QAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSL-QS 634
Query: 500 MPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSPGM-TSGNGNSASSIAGTAPQNGENK 558
P LP S +I P G SPG+ TSG +S Q ++
Sbjct: 635 RPSSLP-DLSGSIDDLPMGTEG---------ALSPGVSTSGISSS---------QGEQSN 675
Query: 559 PPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLP-EKLPQQDHTT 617
P Q+ P H + G G P PVG + + + + +P ++P + +
Sbjct: 676 PAQSPFSPHTSPH-LPGI---RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG 731
Query: 618 TTDSEMEEPYLQES 631
+DS M Q S
Sbjct: 732 QSDSIMHPSMNQSS 745
Score = 40.8 bits (94), Expect = 0.005
Identities = 125/600 (20%), Positives = 190/600 (31%), Gaps = 111/600 (18%)
Query: 11 SSSACATSSTSGASSSSG---CNNSSSGGSGRPTG--PQISVYSGIPDRQTVQVI----- 60
+++A A +++ GA S + SSGG G+P PQ S + Q
Sbjct: 341 AAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNP 400
Query: 61 ---QQALHRQPSTAAQYLQQMYAAQ--QQHLMLQTAALQQQHLSSAQLQSLAAV-QQASL 114
QQ P Y Q Y +Q Q++ M Q + Q + QQ
Sbjct: 401 YSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPS 460
Query: 115 VSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNT 174
+QG T N + P Q P +Q + S A QQ +
Sbjct: 461 GYGQQGQTPYYNQQSPHPQQQ-------QPPYSQ---QPPSQTPHAQPSYQQQP----QS 506
Query: 175 SSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPP---TPAQVQNLTLRTQQ 231
P L +SQ + P++PP +PA + TQQ
Sbjct: 507 QPPQLQSSQPPY-----------------------SQQPSQPPHQQSPAPYPSQQSTTQQ 543
Query: 232 TPAAAA--SGPTPTQPVLPSLALKPTPG-----GSQPLPTPAQSRNTAQASPAGAKPGIA 284
P + S P P +P P + P P QS+ TA + P
Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP--- 600
Query: 285 DSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHL 344
+ G SS P + G ++ + P P + LP + L
Sbjct: 601 -QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD--LPMGTEGAL 657
Query: 345 QPQFVIQQQPQPQQQQPPPQQSRPVLQAEPH-PQLASVSPSVALQPSSEAHAMPLGPVTP 403
P Q +Q P QS PH P + SPS P+S A + GP++P
Sbjct: 658 SPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRS-GPLSP 716
Query: 404 ALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASP 463
A PG PP +G + + H + +
Sbjct: 717 AA----------VPGNQMPPRPP-------SGQSDSIMHPSMNQSSIAQDRGYMQRNPQM 759
Query: 464 PQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAM---------PGGLPVPTSPNIQP 514
PQ P ++P + S + +G +QQ + + GG P + N P
Sbjct: 760 PQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALP 819
Query: 515 SPAHETGQGIVHALTDLSSPGMTSGN-----------GNSASSIAGTAP--QNGENKPPQ 561
+ A+ G+ + + + G G G + + G P N N PPQ
Sbjct: 820 N-ANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQ 878
Score = 35.4 bits (80), Expect = 0.23
Identities = 30/88 (34%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 353 QPQPQQQQPPPQQSRPVLQ---AEPHPQLASVSPSVALQPSSEAHA---MPLGPVTPALP 406
Q QPQQQQ PP Q +P Q A+P PQ + P++ A P G P
Sbjct: 1397 QGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFP 1456
Query: 407 LQCPTANLHKPGG--SQQCHPPTPDTGP 432
Q + P G +QQ PP GP
Sbjct: 1457 FQFGRDRVSAPPGTNAQQNMPPQMMGGP 1484
Score = 33.1 bits (74), Expect = 1.1
Identities = 77/349 (22%), Positives = 115/349 (32%), Gaps = 45/349 (12%)
Query: 258 GSQPLPTPAQSRNTAQASP--AGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVP 315
GS P + Q N P A PG+ + M P + G RT P
Sbjct: 1241 GSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG--------GPYDRVRTEP 1292
Query: 316 AVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPH 375
+ ++ Q P+ + P S P QQ Q QQQ+ ++ Q P
Sbjct: 1293 GIGPEGNMSTGAPQ--PNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPS 1350
Query: 376 PQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNG 435
+ Q + + P+ P A H+ G P + G Q
Sbjct: 1351 GSPFPSQQTTMYQQQQQNYKRPMDGT------YGPPAKRHE--GEMYSVPYSTGQG-QPQ 1401
Query: 436 HPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPG-EKSVPETRSGPSPHQQ 494
+ P PQ Q +A QP+ PQQ V + + P + E R P Q
Sbjct: 1402 QQQLPPAQPQPASQQQAA-----QPS--PQQDVYNQYGNAYPATATAATERRPAGGPQNQ 1454
Query: 495 AIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSPG--------MTSGNGNSASS 546
+ P N Q + + G + A +++ G MT N S+
Sbjct: 1455 FPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQST 1514
Query: 547 IAGTAPQ----NGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSS 591
G+APQ +G N+ + + Q H EG G P G S+
Sbjct: 1515 --GSAPQGPAYHGVNRTDEMLHTDQRANH--EGSWPSHGTRQPPYGPSA 1559
Score = 33.1 bits (74), Expect = 1.1
Identities = 74/340 (21%), Positives = 110/340 (32%), Gaps = 75/340 (22%)
Query: 211 GSPARPPTPAQVQNLTLRTQQT---PAAAASGPTPTQPVLPSLALKPTPGGSQPL----- 262
G+P+ P P+Q + + QQ P GP + ++ + G QP
Sbjct: 1347 GTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLP 1406
Query: 263 ---PTPAQSRNTAQASP--------AGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLS 311
P PA + AQ SP A P A + E G + P GR +S
Sbjct: 1407 PAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQF-GRDRVS 1465
Query: 312 RTVPAVAAHPLIAPAYAQLQPHQLLPQP--SSKHLQPQFVIQQQPQPQQQQPPPQQSRPV 369
P A Q P Q++ P +S + Q + Q +QS
Sbjct: 1466 AP-PGTNAQ--------QNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTG- 1515
Query: 370 LQAEPHPQLASVSPSVALQ------------PSSEAHAMPLGPVTPALPLQCPTANLHKP 417
A P V+ + + PS P GP P P+ P + ++P
Sbjct: 1516 -SAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQP 1574
Query: 418 GGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVIL----QLQPASPPQQCVPDDWK 473
S Q H PQ P +P + R + + L ++Q A PP
Sbjct: 1575 PPSMQNHI------PQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPP--------- 1619
Query: 474 EVAPGEKSVPETRSGPSPHQQAIV---TAMPGGLPVPTSP 510
VP + P+P Q ++ P G T P
Sbjct: 1620 --------VPASHIAPAPVQPPMIRRDITFPPGSVEATQP 1651
Score = 30.0 bits (66), Expect = 9.6
Identities = 49/197 (24%), Positives = 70/197 (35%), Gaps = 33/197 (16%)
Query: 205 QPELGTGSPARPPTPAQ-VQN---------LTLRTQQTPAAAASGPTPTQPVLPSLALKP 254
QP+ + A P+P Q V N T T++ PA P Q ++ P
Sbjct: 1409 QPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPP 1468
Query: 255 TPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSM-EGRA--GLS 311
Q +P P QAS A+ G N GS +G A G++
Sbjct: 1469 GTNAQQNMP-PQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVN 1527
Query: 312 RTVPAV-----AAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQS 366
RT + A H P++ QP P S + P +P P QPPP
Sbjct: 1528 RTDEMLHTDQRANHEGSWPSHGTRQP----PYGPSAPVPPM----TRPPPSNYQPPPSMQ 1579
Query: 367 RPVLQAEPHPQLASVSP 383
+ PQ++S +P
Sbjct: 1580 NHI------PQVSSPAP 1590
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 64.3 bits (155), Expect = 5e-10
Identities = 129/554 (23%), Positives = 191/554 (34%), Gaps = 70/554 (12%)
Query: 112 ASLVSNRQGSTSGSNVSAQA-----PAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQ 166
A +S+ +G T GS +A A P+ S+S + ++S A Q +AA G
Sbjct: 228 AYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTP 287
Query: 167 QAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLT 226
Q + + S A+ Y P + + G G + P Q
Sbjct: 288 QPTATPTLNQLLTSPSSARGYQGY------PGGDYSGGPQDGGAG---KGPADMASQCWG 338
Query: 227 LRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLP-TPAQSRNTAQASPAGAKPGIAD 285
AAAASG + ++ + GG QPL TP S Q +P
Sbjct: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGT 398
Query: 286 SVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQ-----LQPHQLLPQPS 340
+ P+ + G S P G G +P+ AQ L Q +P
Sbjct: 399 N---PYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYG 455
Query: 341 SKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLG- 399
+ Q P QQ P PQQ +P +P Q PS QP S+ +
Sbjct: 456 QQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQ 515
Query: 400 PVTPALPLQCPTANLHKPGGSQQC----HPPT--PDTGPQNGHP-------EGVPHT--- 443
P P Q P P SQQ HP + P + PQ P + P T
Sbjct: 516 PPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQ 575
Query: 444 ----PQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTA 499
PQ + Q + Q PPQ+ D + A S+ ++ G ++ +
Sbjct: 576 QAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSL-QS 634
Query: 500 MPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSPGM-TSGNGNSASSIAGTAPQNGENK 558
P LP S +I P G SPG+ TSG +S Q ++
Sbjct: 635 RPSSLP-DLSGSIDDLPMGTEG---------ALSPGVSTSGISSS---------QGEQSN 675
Query: 559 PPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLP-EKLPQQDHTT 617
P Q+ P H + G G P PVG + + + + +P ++P + +
Sbjct: 676 PAQSPFSPHTSPH-LPGI---RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG 731
Query: 618 TTDSEMEEPYLQES 631
+DS M Q S
Sbjct: 732 QSDSIMHPSMNQSS 745
Score = 40.8 bits (94), Expect = 0.005
Identities = 125/600 (20%), Positives = 190/600 (31%), Gaps = 111/600 (18%)
Query: 11 SSSACATSSTSGASSSSG---CNNSSSGGSGRPTG--PQISVYSGIPDRQTVQVI----- 60
+++A A +++ GA S + SSGG G+P PQ S + Q
Sbjct: 341 AAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNP 400
Query: 61 ---QQALHRQPSTAAQYLQQMYAAQ--QQHLMLQTAALQQQHLSSAQLQSLAAV-QQASL 114
QQ P Y Q Y +Q Q++ M Q + Q + QQ
Sbjct: 401 YSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPS 460
Query: 115 VSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNT 174
+QG T N + P Q P +Q + S A QQ +
Sbjct: 461 GYGQQGQTPYYNQQSPHPQQQ-------QPPYSQ---QPPSQTPHAQPSYQQQP----QS 506
Query: 175 SSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPP---TPAQVQNLTLRTQQ 231
P L +SQ + P++PP +PA + TQQ
Sbjct: 507 QPPQLQSSQPPY-----------------------SQQPSQPPHQQSPAPYPSQQSTTQQ 543
Query: 232 TPAAAA--SGPTPTQPVLPSLALKPTPG-----GSQPLPTPAQSRNTAQASPAGAKPGIA 284
P + S P P +P P + P P QS+ TA + P
Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP--- 600
Query: 285 DSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHL 344
+ G SS P + G ++ + P P + LP + L
Sbjct: 601 -QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD--LPMGTEGAL 657
Query: 345 QPQFVIQQQPQPQQQQPPPQQSRPVLQAEPH-PQLASVSPSVALQPSSEAHAMPLGPVTP 403
P Q +Q P QS PH P + SPS P+S A + GP++P
Sbjct: 658 SPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRS-GPLSP 716
Query: 404 ALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASP 463
A PG PP +G + + H + +
Sbjct: 717 AA----------VPGNQMPPRPP-------SGQSDSIMHPSMNQSSIAQDRGYMQRNPQM 759
Query: 464 PQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAM---------PGGLPVPTSPNIQP 514
PQ P ++P + S + +G +QQ + + GG P + N P
Sbjct: 760 PQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALP 819
Query: 515 SPAHETGQGIVHALTDLSSPGMTSGN-----------GNSASSIAGTAP--QNGENKPPQ 561
+ A+ G+ + + + G G G + + G P N N PPQ
Sbjct: 820 N-ANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQ 878
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 63.9 bits (154), Expect = 6e-10
Identities = 107/466 (22%), Positives = 161/466 (34%), Gaps = 87/466 (18%)
Query: 115 VSNRQGSTSGSNVSAQAP-------AQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQ 167
++ R G G+ + AP A +SS N A+ P A+ RA + + ++
Sbjct: 58 LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117
Query: 168 AVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGS--PARPPTPAQVQNL 225
G T L Q + + A+ + AT A + L G+ PTP
Sbjct: 118 GRASGTTRPGPL--GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175
Query: 226 TLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAK-PGIA 284
R + P P PS +P G + + A +T + SPA + P
Sbjct: 176 MARRSRAAGTEVGLPRPA----PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 285 DSVMEPHKKGDGNSSVPGSMEGRAGLS-RTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKH 343
+ P + +S+ P S R+G S R P AHP
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS--------------------- 270
Query: 344 LQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPS-SEAHAMPLGPVT 402
Q +P+ Q PPQ + P A P S SP PS ++A +P P
Sbjct: 271 -------QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP-PPDN 322
Query: 403 PALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPAS 462
A PL PP+P +P P S L PA+
Sbjct: 323 AATPLPATL-------------PPSPPLATP------LPLAPPSPSAPPSLQTLPSPPAT 363
Query: 463 PPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVP-TSPNIQPSPAHETG 521
PP Q AP + P ++ PS + T P +P TSP++Q +P
Sbjct: 364 PPSQ---------APPSMTTPPMQAPPS-----LQTIPPIQVPHSLTSPSLQ-APPSPLA 408
Query: 522 QGIVHALTDLSSPGMTSGNGNSASS-----IAGTAPQNGENKPPQA 562
+ A T L SP + + + S + T+P + PP +
Sbjct: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454
Score = 60.8 bits (146), Expect = 5e-09
Identities = 126/486 (25%), Positives = 170/486 (34%), Gaps = 64/486 (13%)
Query: 52 PDRQTVQVIQQALH-RQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQ 110
P QT+ IQ PS A ++ Q L + LQ H + L
Sbjct: 381 PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH---SFLTMSPRQT 437
Query: 111 QASLVS-NRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAV 169
QASL S +R ST + QAP ++L ASP L+ A S S+ + QA+
Sbjct: 438 QASLTSPSRPASTPPDSPPLQAP-----LSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492
Query: 170 LLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRT 229
SS A + QA + LI P T +++ P PA TP +L
Sbjct: 493 -----SSLASHSPQAPL----SSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAP 543
Query: 230 QQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPT-PAQSRNTAQASPAGAKPGIADSVM 288
A+A TP P A P PL T P ++ ++ P A P +A +
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603
Query: 289 E--PHKKGDGNSSVPGSMEGRAGLS--RTVPAVAAHPLIAP-------AYAQLQPHQL-- 335
+ P ++ P L + P+ A P ++P A L H L
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 663
Query: 336 -LPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAH 394
P S +Q F P PP Q+ P L A P V PS P
Sbjct: 664 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP----LQVPPSPPASPPMSPS 719
Query: 395 AMPLGPVTPAL---PLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHT 451
A P P L PLQ P + P S PP P VP +P
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP------- 772
Query: 452 SAVILQLQP-ASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSP 510
L + P A PP Q AP + P ++ PSP + PG P S
Sbjct: 773 -PASLPMSPLAKPPPQ---------APPALATPPLQALPSP-----PASFPGQAPFSPSA 817
Query: 511 NIQPSP 516
++ SP
Sbjct: 818 SLPMSP 823
Score = 57.8 bits (138), Expect = 4e-08
Identities = 130/547 (23%), Positives = 191/547 (34%), Gaps = 77/547 (14%)
Query: 8 PHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALHRQ 67
P S S+ + ST+ S ++ S+ GG RP +S + +
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS--------SSATPLSSPARSG 256
Query: 68 PSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGSNV 127
PS + +Q + LQ AL+ ++ + + A+ S S SG+
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQ--ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKA 314
Query: 128 SAQAPAQSSSINLAA----SPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQ 183
P +++ L A SP A L A SA S L S PA SQ
Sbjct: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS-------LQTLPSPPATPPSQ 367
Query: 184 AQMYLRAQMLIFTPT-ATVATVQPELGTGSPA--RPPTPAQVQN---------------- 224
A + + P+ T+ +Q SP+ PP+P + +
Sbjct: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427
Query: 225 --LTLRTQQTPAA--AASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAK 280
LT+ +QT A+ + S P T P P L + S PL T + +SP
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487
Query: 281 PGIADSVMEPHK-KGDGNSSVPGSMEGRAGL----------SRTVPAVAAHPLIAPAYAQ 329
P A S + H + +S + +E ++ L S T P + P +AP Q
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ 547
Query: 330 LQPHQL-LPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQ 388
L P + +Q P P PP P A P PQ P++A
Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPP---ETPSSIATPPPQ---APPALASP 601
Query: 389 PSSEAHAMPLGPV-TPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRR 447
P + PL P+ TP P Q P P + PP+P P P TP +
Sbjct: 602 PLQGLPSPPLSPLATP--PPQAPPXLALPPLQA----PPSPPASP----PLSPLATPSPQ 651
Query: 448 FQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVP 507
+ AV L P SPP P + + P +P QA + L VP
Sbjct: 652 APNALAVHLLQAPFSPP----PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707
Query: 508 TSPNIQP 514
SP P
Sbjct: 708 PSPPASP 714
>gi|53692193 Scm-like with four mbt domains 1 [Homo sapiens]
Length = 866
Score = 63.9 bits (154), Expect = 6e-10
Identities = 49/136 (36%), Positives = 64/136 (47%), Gaps = 10/136 (7%)
Query: 729 QLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPD--------MHMRDLV 780
+L E S + S +SS + S RR++ R D +R V
Sbjct: 724 ELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEV 783
Query: 781 GMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNI 840
H L S P KW+V DV FIRS C +A F QEIDGQALLLL + M++
Sbjct: 784 AERLH-LDSNPLKWSVADVVRFIRSTD-CAPLARIFLDQEIDGQALLLLTLPTVQECMDL 841
Query: 841 KLGPALKIYARISMLK 856
KLGPA+K+ I +K
Sbjct: 842 KLGPAIKLCHHIERIK 857
>gi|53692191 Scm-like with four mbt domains 1 [Homo sapiens]
Length = 866
Score = 63.9 bits (154), Expect = 6e-10
Identities = 49/136 (36%), Positives = 64/136 (47%), Gaps = 10/136 (7%)
Query: 729 QLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPD--------MHMRDLV 780
+L E S + S +SS + S RR++ R D +R V
Sbjct: 724 ELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEV 783
Query: 781 GMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNI 840
H L S P KW+V DV FIRS C +A F QEIDGQALLLL + M++
Sbjct: 784 AERLH-LDSNPLKWSVADVVRFIRSTD-CAPLARIFLDQEIDGQALLLLTLPTVQECMDL 841
Query: 841 KLGPALKIYARISMLK 856
KLGPA+K+ I +K
Sbjct: 842 KLGPAIKLCHHIERIK 857
>gi|53692195 Scm-like with four mbt domains 1 [Homo sapiens]
Length = 866
Score = 63.9 bits (154), Expect = 6e-10
Identities = 49/136 (36%), Positives = 64/136 (47%), Gaps = 10/136 (7%)
Query: 729 QLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPD--------MHMRDLV 780
+L E S + S +SS + S RR++ R D +R V
Sbjct: 724 ELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEV 783
Query: 781 GMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNI 840
H L S P KW+V DV FIRS C +A F QEIDGQALLLL + M++
Sbjct: 784 AERLH-LDSNPLKWSVADVVRFIRSTD-CAPLARIFLDQEIDGQALLLLTLPTVQECMDL 841
Query: 841 KLGPALKIYARISMLK 856
KLGPA+K+ I +K
Sbjct: 842 KLGPAIKLCHHIERIK 857
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 63.5 bits (153), Expect = 8e-10
Identities = 71/251 (28%), Positives = 90/251 (35%), Gaps = 42/251 (16%)
Query: 278 GAKPGIADSVMEPHKKGDGNSSVP-GSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLL 336
G + G+ D P G + P G G++G +P H Q P Q
Sbjct: 23 GGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQ----QQQQPPPQQPP 78
Query: 337 PQPSSKHLQPQFVIQQQPQPQQQQ---PPPQ-QSRPVLQAEPHPQLASVSPSVALQPSSE 392
PQ H P PQP QQQ PPPQ S+PV+ P P +P V P +
Sbjct: 79 PQQPPPHQPPP-----HPQPHQQQQPPPPPQDSSKPVVAQGPGP-----APGVGSAPPAS 128
Query: 393 AHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTS 452
+ A P P T P GS PTP + P P TP +S
Sbjct: 129 SSAPPATPPTSG-----------APPGSGPGPTPTPPPAVTSAPPGAPPPTPP-----SS 172
Query: 453 AVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTA--MPGGLPVPTSP 510
V P +PPQ P PG P+ GP + + PGG P ++P
Sbjct: 173 GV-----PTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTP 227
Query: 511 NIQPSPAHETG 521
P P H G
Sbjct: 228 GGHPKPPHRGG 238
Score = 47.0 bits (110), Expect = 8e-05
Identities = 64/234 (27%), Positives = 71/234 (30%), Gaps = 55/234 (23%)
Query: 332 PHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQL-ASVSPSVALQPS 390
P Q P+P P QQQ QP QQPPPQQ P Q PHPQ P Q S
Sbjct: 51 PGQSGPKPPIPPPPPH---QQQQQPPPQQPPPQQPPPH-QPPPHPQPHQQQQPPPPPQDS 106
Query: 391 SEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQH 450
S+ PV P P P S P T P +G P G P
Sbjct: 107 SK-------PVVAQGPGPAPGVGSAPPASSSA----PPATPPTSGAPPGSGPGPT----- 150
Query: 451 TSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSP 510
+PP P S P P+P + T P P P
Sbjct: 151 ----------PTPP------------PAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188
Query: 511 NIQPSPAHETGQGIVHALTDLSSPGMTSG----NGNSASSIAGTAPQNGENKPP 560
P P QG PG G G G + G KPP
Sbjct: 189 AAVPGPGPGPKQG--------PGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPP 234
Score = 40.8 bits (94), Expect = 0.005
Identities = 63/239 (26%), Positives = 72/239 (30%), Gaps = 35/239 (14%)
Query: 209 GTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTP-GGSQPLPTPAQ 267
G P PP P Q Q QQ P P P QP P P QP P P
Sbjct: 55 GPKPPIPPPPPHQQQ------QQPP---PQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQD 105
Query: 268 SRNTAQASPAGAKPGIAD----SVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLI 323
S A G PG+ S P + + PGS G PAV + P
Sbjct: 106 SSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS--GPGPTPTPPPAVTSAPPG 163
Query: 324 APAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSP 383
AP P P P + P PPP + P P P
Sbjct: 164 APP----------PTP------PSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGP 207
Query: 384 SVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPP---TPDTGPQNGHPEG 439
P G TP + P +P G +Q HPP GP G P G
Sbjct: 208 KGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGG 266
Score = 40.8 bits (94), Expect = 0.005
Identities = 48/161 (29%), Positives = 57/161 (35%), Gaps = 19/161 (11%)
Query: 206 PELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTP 265
P G GS PP + T T P + GPTPT P P++ P PG P PTP
Sbjct: 117 PAPGVGSA--PPASSSAPPATPPTSGAPPGSGPGPTPTPP--PAVTSAP-PGA--PPPTP 169
Query: 266 AQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHP-LIA 324
S AG P +V P G G PG + G P P L
Sbjct: 170 PSSGVPTTPPQAGGPPPPPAAVPGP---GPGPKQGPGPGGPKGGKMPGGPKPGGGPGLST 226
Query: 325 PAYAQLQPHQ--LLPQPSSKHLQPQFVIQQQPQPQQQQPPP 363
P PH+ P+ +H P Q Q PPP
Sbjct: 227 PGGHPKPPHRGGGEPRGGRQHHPPYH------QQHHQGPPP 261
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 63.2 bits (152), Expect = 1e-09
Identities = 102/379 (26%), Positives = 135/379 (35%), Gaps = 61/379 (16%)
Query: 209 GTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGS----QPLPT 264
G G P RP P+ R PA GP P P+ L+P P GS P+P
Sbjct: 98 GGGGPQRPGPPSP------RRPLVPA----GPAP-----PAAKLRPPPEGSAGSCAPVPA 142
Query: 265 PAQSRNTAQASPAG-AKPGIADSVMEPHKKGDGNSSVPGSMEGRA-----GLSRTVPAVA 318
A + +PAG AKP ++ G G PG G G ++T+ A
Sbjct: 143 AAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSA 202
Query: 319 A----HPLIAPAYAQLQ--PHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQA 372
A H APA + + P LLP P K P VI Q+ P + A
Sbjct: 203 ALLNSHHAAAPAVSLVNNGPAALLPLP--KPAAPGTVI--------------QTPPFVGA 246
Query: 373 EPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGP 432
P A+ SP A P++ A A P P PA + P H G P
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPG---HPAGPPTAAPAVPPPAAA 303
Query: 433 QNGHPEGVPHTPQRRFQHTSAVILQLQP----ASPPQQCVPDDWKEVAPGEKSVPETRSG 488
QNG G P + V Q P A+P + K V +T +
Sbjct: 304 QNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAA 363
Query: 489 PSPHQQA----IVTAMPGGLPVPTSPNIQPSPAHETG--QGIVHALTDLSSPGMTSGNGN 542
P A I M G LP P + P+P TG +G A+T S T+
Sbjct: 364 SGPASTAASMVIGPTMQGALPSPAAVP-PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSG 422
Query: 543 SASSIAGTAPQNGENKPPQ 561
+++ T +PPQ
Sbjct: 423 IRATLTPTVLAPRLPQPPQ 441
Score = 50.4 bits (119), Expect = 7e-06
Identities = 81/292 (27%), Positives = 101/292 (34%), Gaps = 62/292 (21%)
Query: 296 GNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQ 355
GN V GS G AG PA A P AP P P+ + +P Q+P
Sbjct: 59 GNHVVSGSPAGAAGAGPAAPAEGA-PGAAPE----------PPPAGR-ARPGGGGPQRP- 105
Query: 356 PQQQQPPPQQSRPVLQAEPHPQLASVSP-------SVALQPSSEAHA-----MPLGPVTP 403
PP RP++ A P P A + P S A P++ A A P GP P
Sbjct: 106 -----GPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKP 160
Query: 404 ALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASP 463
A P A L G P P GP G P G P Q + SA +L A+
Sbjct: 161 AGP-----AALAARAGPGPGPGPGPGPGPGPGKPAG-PGAAQT--LNGSAALLNSHHAAA 212
Query: 464 PQQCVPDDW--------KEVAPGE---------KSVPETRSGPSPHQQAIVTAMPGGLPV 506
P + ++ K APG + P + PSP A A P P
Sbjct: 213 PAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSP-PAAPAPAAPAAAPP 271
Query: 507 PTSP---NIQPSPAHETGQGIVHALTDLSSPGMTSGNGNSASSIAGTAPQNG 555
P P + P H G P + NG SA + AP G
Sbjct: 272 PPPPAPATLARPPGHPAGP---PTAAPAVPPPAAAQNGGSAGAAPAPAPAAG 320
Score = 49.3 bits (116), Expect = 2e-05
Identities = 113/471 (23%), Positives = 151/471 (32%), Gaps = 89/471 (18%)
Query: 142 ASPAAAQLLN-RAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTAT 200
A P AAQ LN A +NS A A AV L N AL +I TP
Sbjct: 190 AGPGAAQTLNGSAALLNSHHA---AAPAVSLVNNGPAALLPLPKPA--APGTVIQTPPFV 244
Query: 201 VATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAA------SGPTPTQPVLPSLALKP 254
A P SP P PA PA A +GP P +P A
Sbjct: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQ 304
Query: 255 TPGGSQPLPTPAQSRNTAQASPAGAK----PGIADSVMEPHKKGD--------------- 295
G + P PA A PAG PG A + P K +
Sbjct: 305 NGGSAGAAPAPA----PAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQT 360
Query: 296 ----GNSSVPGSMEGRAGLSRTVPAVAAHPLIAP----------AYAQLQPHQLLPQPSS 341
G +S SM + +P+ AA P AP A A Q P ++
Sbjct: 361 LAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATT 420
Query: 342 K----HLQPQFVIQQQPQPQQQ-------QPPPQQSRPVLQAEPHPQLASVSPSVALQPS 390
L P + + PQP Q Q PP VL + QL + Q
Sbjct: 421 SGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGM---VLVRSENGQLLMIPQQALAQMQ 477
Query: 391 SEAHAMPLGPVT--PALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRF 448
++AHA P + PA P P + S P TP Q TP
Sbjct: 478 AQAHAQPQTTMAPRPATPTSAPPVQI-----STVQAPGTPIIARQ--------VTPTTII 524
Query: 449 QHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPT 508
+ S +QP++ Q+ +PG + TA+ G P T
Sbjct: 525 KQVSQAQTTVQPSATLQR---------SPGVQPQLVLGGAAQTASLGTATAVQTGTPQRT 575
Query: 509 SP--NIQPSPAHETGQGIVHALTDLSSPGMTSGNGNSASSIAGTAPQNGEN 557
P S A ET + + LS+ + +G ++ A + +N
Sbjct: 576 VPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQN 626
Score = 40.8 bits (94), Expect = 0.005
Identities = 105/437 (24%), Positives = 150/437 (34%), Gaps = 61/437 (13%)
Query: 231 QTP--AAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVM 288
QTP AA+ P P P P+ P + P P PA + P A +V
Sbjct: 239 QTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP 298
Query: 289 EPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQF 348
P +G S+ G+ A + V+ P A A P P K P+
Sbjct: 299 PPAAAQNGGSA--GAAPAPAPAAGGPAGVSGQPGPGAAAA-------APAPGVKAESPKR 349
Query: 349 VIQQQPQPQQ--QQPPPQQSRPVLQAEPHPQLASVSPSVALQPS-SEAHAMP---LGPVT 402
V+Q P Q P + + P Q A SP+ P+ +P G VT
Sbjct: 350 VVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVT 409
Query: 403 PALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVIL----QL 458
+L + PTA G + PT P+ P P T + FQ ++L
Sbjct: 410 QSLS-RTPTAT---TSGIRATLTPTV-LAPRLPQPPQNP-TNIQNFQLPPGMVLVRSENG 463
Query: 459 QPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQA------IVTAMPGGLPV------ 506
Q PQQ + ++ + P+T P P I T G P+
Sbjct: 464 QLLMIPQQAL----AQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVT 519
Query: 507 PTSPNIQPSPAHETGQGIVHALTDLSSPG-----MTSGNGNSASSIAGTAPQNG--ENKP 559
PT+ Q S A T Q + T SPG + G +AS TA Q G +
Sbjct: 520 PTTIIKQVSQAQTTVQ---PSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTV 576
Query: 560 PQAIVKPQILTHVIEGF-----VIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQD 614
P A T +E + + G+ S K+ Q L K+ +D
Sbjct: 577 PGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAED 636
Query: 615 HTTTTDSEME---EPYL 628
T+ E+ +PYL
Sbjct: 637 FTSRLYRELNSSPQPYL 653
Score = 40.8 bits (94), Expect = 0.005
Identities = 135/574 (23%), Positives = 193/574 (33%), Gaps = 115/574 (20%)
Query: 8 PHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALHRQ 67
P T++ A + + S+G + + +G P G SG P
Sbjct: 290 PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAG-----VSGQPG-------------- 330
Query: 68 PSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGST-SGSN 126
P AA A+ ++Q A Q L+++ S AA + QG+ S +
Sbjct: 331 PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAA--SMVIGPTMQGALPSPAA 388
Query: 127 VSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQM 186
V AP + + A+ A Q L+R + ++ VL P + Q
Sbjct: 389 VPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQN 448
Query: 187 Y--------LRAQ--MLIFTPTATVATVQPELG----TGSPARPPTPAQVQNLTLRTQQT 232
+ +R++ L+ P +A +Q + T RP TP + + T Q
Sbjct: 449 FQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQA 508
Query: 233 PAAA--ASGPTPTQ----------PVLPSLALKPTPGGSQPL----PTPAQSRNTAQA-- 274
P A TPT V PS L+ +PG L S TA A
Sbjct: 509 PGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQ 568
Query: 275 --SPAGAKPGI------ADSVMEPHKKGDG--------NSSVPGSMEGRAGLSRTVP--- 315
+P PG A ME KK SS S E A + V
Sbjct: 569 TGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLL 628
Query: 316 --AVAAHPLIAPAYAQL----QPHQLLP-----QPSSKHLQPQFV--IQQQPQPQQQQPP 362
+ A + Y +L QP+ L+P P+ + L P IQQ QQQPP
Sbjct: 629 DGKIEAEDFTSRLYRELNSSPQPY-LVPFLKRSLPALRQLTPDSAAFIQQS----QQQPP 683
Query: 363 PQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPT-ANLHKPGGSQ 421
P P QA +S SV A + P L L PT + K G
Sbjct: 684 P----PTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQG--- 736
Query: 422 QCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPAS------------PPQQCVP 469
PTP Q P + PQ T V L+ QP + P Q VP
Sbjct: 737 ---QPTPLVIQQPPKPGALIRPPQVTLTQTPMVALR-QPHNRIMLTTPQQIQLNPLQPVP 792
Query: 470 DDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGG 503
V PG K++ + + Q+ + GG
Sbjct: 793 VVKPAVLPGTKALSAVSAQAAAAQKNKLKEPGGG 826
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,016,996
Number of Sequences: 37866
Number of extensions: 2501346
Number of successful extensions: 23451
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 281
Number of HSP's successfully gapped in prelim test: 1389
Number of HSP's that attempted gapping in prelim test: 12676
Number of HSP's gapped (non-prelim): 7079
length of query: 858
length of database: 18,247,518
effective HSP length: 111
effective length of query: 747
effective length of database: 14,044,392
effective search space: 10491160824
effective search space used: 10491160824
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.