BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] (530 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] 1036 0.0 gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 1018 0.0 gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens] 472 e-133 gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens] 459 e-129 gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] 434 e-122 gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 102 9e-22 gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 102 9e-22 gi|7706607 LEM domain containing 3 [Homo sapiens] 102 1e-21 gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 100 3e-21 gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofor... 89 8e-18 gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofo... 88 2e-17 gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 87 3e-17 gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ... 83 5e-16 gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform ... 83 5e-16 gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 83 5e-16 gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 83 5e-16 gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo... 83 7e-16 gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 81 3e-15 gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 81 3e-15 gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 81 3e-15 gi|20373175 musashi 2 isoform a [Homo sapiens] 80 4e-15 gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 80 6e-15 gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 79 8e-15 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 79 8e-15 gi|25121993 musashi 2 isoform b [Homo sapiens] 79 1e-14 gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 79 1e-14 gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 78 2e-14 gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 77 5e-14 gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 76 7e-14 gi|52426743 cisplatin resistance-associated overexpressed protei... 76 9e-14 >gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] Length = 530 Score = 1036 bits (2678), Expect = 0.0 Identities = 530/530 (100%), Positives = 530/530 (100%) Query: 1 MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60 MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD Sbjct: 1 MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60 Query: 61 RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120 RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL Sbjct: 61 RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120 Query: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR Sbjct: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180 Query: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN Sbjct: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240 Query: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD Sbjct: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300 Query: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM Sbjct: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360 Query: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQP 420 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQP Sbjct: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQP 420 Query: 421 LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS 480 LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS Sbjct: 421 LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS 480 Query: 481 IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 530 IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR Sbjct: 481 IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 530 >gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] Length = 524 Score = 1018 bits (2632), Expect = 0.0 Identities = 524/530 (98%), Positives = 524/530 (98%), Gaps = 6/530 (1%) Query: 1 MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60 MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD Sbjct: 1 MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60 Query: 61 RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120 RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL Sbjct: 61 RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120 Query: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR Sbjct: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180 Query: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN Sbjct: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240 Query: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD Sbjct: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300 Query: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM Sbjct: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360 Query: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQP 420 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVA DLQTRLSQQTEASALAAAASVQP Sbjct: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVA------DLQTRLSQQTEASALAAAASVQP 414 Query: 421 LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS 480 LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS Sbjct: 415 LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS 474 Query: 481 IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 530 IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR Sbjct: 475 IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 524 >gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens] Length = 439 Score = 472 bits (1214), Expect = e-133 Identities = 274/471 (58%), Positives = 327/471 (69%), Gaps = 77/471 (16%) Query: 4 DIDIEAMLEAPYKKDENKL---------------SSANGHEERS--------KKRKKSKS 40 DI IEAMLEAPYKK+E++ S++N E S K+K+S+S Sbjct: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRSRS 66 Query: 41 RSRSHERKRSKSKERKRSRDRE-RKKSKSRE-RKRSRSKERRR-SRSRSRDRRFRGR--Y 95 ++S +RKRS+S++R R R R R +S R+ R RSRS +RR S SRSRD R R Y Sbjct: 67 HNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHY 126 Query: 96 RSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTV 155 RSP + R SKSP ++KSPVREP+DNL+PEERDARTV Sbjct: 127 RSP------------------PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTV 168 Query: 156 FCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTG 215 FCMQLAARIRPRDLE+FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTG Sbjct: 169 FCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTG 228 Query: 216 QRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGR 275 QR+LGVPIIVQASQAEKNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+ Sbjct: 229 QRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGK 288 Query: 276 IESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSA 335 I++I LM DS+TGRSKGYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D + Sbjct: 289 IDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD 348 Query: 336 SSFLDSDELERTGIDLGTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSL 385 +F D D+ +DLG+ GR QLMA+LAEG G+Q+P A ALQ++G++ Sbjct: 349 ITFPDGDQ----ELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAV 404 Query: 386 AFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQT 436 GA+ +AL A + LA+QCFQLS++F PQT Sbjct: 405 PLGAL-----------------NPAALTALSPALNLASQCFQLSSLFTPQT 438 >gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens] Length = 423 Score = 459 bits (1180), Expect = e-129 Identities = 266/455 (58%), Positives = 314/455 (69%), Gaps = 61/455 (13%) Query: 4 DIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRS---KSKERKRSRD 60 DI IEAMLEAPYKK+E++ ++ S S S + S ++ R R RD Sbjct: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRD 66 Query: 61 RERKK-SKSRE-----RKRSRSKERRR-SRSRSRDRRFRGR--YRSPYSGPKFNSAIRGK 111 R R++ S+SR R RSRS +RR S SRSRD R R YRSP Sbjct: 67 RYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSP------------- 113 Query: 112 IGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEE 171 + R SKSP ++KSPVREP+DNL+PEERDARTVFCMQLAARIRPRDLE+ Sbjct: 114 -----PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLED 168 Query: 172 FFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAE 231 FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTGQR+LGVPIIVQASQAE Sbjct: 169 FFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAE 228 Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291 KNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+I++I LM DS+TGRSK Sbjct: 229 KNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSK 288 Query: 292 GYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDL 351 GYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D + +F D D+ +DL Sbjct: 289 GYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQ----ELDL 344 Query: 352 GTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSLAFGAVAEFSFVIDLQT 401 G+ GR QLMA+LAEG G+Q+P A ALQ++G++ GA+ Sbjct: 345 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGAL----------- 393 Query: 402 RLSQQTEASALAAAASVQPLATQCFQLSNMFNPQT 436 +AL A + LA+QCFQLS++F PQT Sbjct: 394 ------NPAALTALSPALNLASQCFQLSSLFTPQT 422 >gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] Length = 405 Score = 434 bits (1117), Expect = e-122 Identities = 253/445 (56%), Positives = 297/445 (66%), Gaps = 59/445 (13%) Query: 4 DIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERK-RSRDRE 62 DI IEAMLEAPYKK+E++ ++ S S S + S E RSRDR+ Sbjct: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRD 66 Query: 63 RKKSKSRERKRSRSKERR-RSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLS 121 R + R RSRS R+ R RSRS DRR RS Sbjct: 67 RYR---RRNSRSRSPGRQCRHRSRSWDRRHGSESRS-----------------------R 100 Query: 122 RRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRD 181 R + +R EP+DNL+PEERDARTVFCMQLAARIRPRDLE+FFS VGKVRD Sbjct: 101 DHRREDRVHYRSPPLATGEPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRD 160 Query: 182 VRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANN 241 VR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTGQR+LGVPIIVQASQAEKNR AAMANN Sbjct: 161 VRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANN 220 Query: 242 LQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDS 301 LQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+I++I LM DS+TGRSKGYGFITFSDS Sbjct: 221 LQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDS 280 Query: 302 ECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTT-GRLQLM 360 ECA++ALEQLNGFELAGRPM+VGHVTER D + +F D D+ +DLG+ GR QLM Sbjct: 281 ECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQ----ELDLGSAGGRFQLM 336 Query: 361 ARLAEGTGLQIPPAA---------QQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASA 411 A+LAEG G+Q+P A ALQ++G++ GA+ +A Sbjct: 337 AKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGAL-----------------NPAA 379 Query: 412 LAAAASVQPLATQCFQLSNMFNPQT 436 L A + LA+QCFQLS++F PQT Sbjct: 380 LTALSPALNLASQCFQLSSLFTPQT 404 >gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo sapiens] Length = 516 Score = 102 bits (254), Expect = 9e-22 Identities = 98/437 (22%), Positives = 183/437 (41%), Gaps = 79/437 (18%) Query: 141 PIDNLTPEERDARTVFCMQLAARIRPR----DLEEFFSTVGKVRDVRMISDRNSRRSKGI 196 P+ ++ + + A + C I + + F+ G ++ + M D + + KG Sbjct: 70 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 129 Query: 197 AYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGS 256 A+VE+ + LA+ +LG I + +A + + L + + R+YV S Sbjct: 130 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 189 Query: 257 LHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFEL 316 +H ++++D ++ +FE FG+I+S L D TG+ KGYGFI + ++ ++ A+ +N F+L Sbjct: 190 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 249 Query: 317 AGRPMKVGH--------VTERTD----------ASSASSFLDSDELERTGIDLGTTGRLQ 358 G+ ++VG +T T A++A++ + + E LGT G Sbjct: 250 GGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPG 309 Query: 359 LMA-RLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQT---------------- 401 L++ L L P A A Q G + A + + + Sbjct: 310 LVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGL 369 Query: 402 --------------------RLSQQTEASALAAAAS-------VQPLATQCFQLSNMFNP 434 LS+Q S ++A ++ + L NM +P Sbjct: 370 LEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDP 429 Query: 435 QTEEEVGWDTEIKDDVIEECNKHGGV--IHIYVDKNSAQGN------VYVKCPSIAAAIA 486 + D +++ +V EEC K G V + IY +K + + ++V+ + Sbjct: 430 K-----DIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHK 484 Query: 487 AVNALHGRWFAGKMITA 503 A+ AL+GRWFAG+ + A Sbjct: 485 AIQALNGRWFAGRKVVA 501 >gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo sapiens] Length = 559 Score = 102 bits (254), Expect = 9e-22 Identities = 98/437 (22%), Positives = 183/437 (41%), Gaps = 79/437 (18%) Query: 141 PIDNLTPEERDARTVFCMQLAARIRPR----DLEEFFSTVGKVRDVRMISDRNSRRSKGI 196 P+ ++ + + A + C I + + F+ G ++ + M D + + KG Sbjct: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172 Query: 197 AYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGS 256 A+VE+ + LA+ +LG I + +A + + L + + R+YV S Sbjct: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232 Query: 257 LHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFEL 316 +H ++++D ++ +FE FG+I+S L D TG+ KGYGFI + ++ ++ A+ +N F+L Sbjct: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292 Query: 317 AGRPMKVGH--------VTERTD----------ASSASSFLDSDELERTGIDLGTTGRLQ 358 G+ ++VG +T T A++A++ + + E LGT G Sbjct: 293 GGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPG 352 Query: 359 LMA-RLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQT---------------- 401 L++ L L P A A Q G + A + + + Sbjct: 353 LVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGL 412 Query: 402 --------------------RLSQQTEASALAAAAS-------VQPLATQCFQLSNMFNP 434 LS+Q S ++A ++ + L NM +P Sbjct: 413 LEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDP 472 Query: 435 QTEEEVGWDTEIKDDVIEECNKHGGV--IHIYVDKNSAQGN------VYVKCPSIAAAIA 486 + D +++ +V EEC K G V + IY +K + + ++V+ + Sbjct: 473 K-----DIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHK 527 Query: 487 AVNALHGRWFAGKMITA 503 A+ AL+GRWFAG+ + A Sbjct: 528 AIQALNGRWFAGRKVVA 544 >gi|7706607 LEM domain containing 3 [Homo sapiens] Length = 911 Score = 102 bits (253), Expect = 1e-21 Identities = 47/108 (43%), Positives = 68/108 (62%) Query: 423 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIA 482 T C ++ NMF+P E W I++ ++E+C+ + G++HI VDKNS +G VYVKC S Sbjct: 783 TPCLKIRNMFDPVMEIGDQWHLAIQEAILEKCSDNDGIVHIAVDKNSREGCVYVKCLSPE 842 Query: 483 AAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 530 A A ALHG WF GK++T Y+ L YH+ FP ++T+ L PS + Sbjct: 843 YAGKAFKALHGSWFDGKLVTVKYLRLDRYHHRFPQALTSNTPLKPSNK 890 >gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo sapiens] Length = 542 Score = 100 bits (250), Expect = 3e-21 Identities = 94/405 (23%), Positives = 173/405 (42%), Gaps = 75/405 (18%) Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQAS 228 + + F+ G ++ + M D + + KG A+VE+ + LA+ +LG I Sbjct: 128 IRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGR 187 Query: 229 QAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETG 288 + +A + + L + + R+YV S+H ++++D ++ +FE FG+I+S L D TG Sbjct: 188 PSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTG 247 Query: 289 RSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGH--------VTERTD--------- 331 + KGYGFI + ++ ++ A+ +N F+L G+ ++VG +T T Sbjct: 248 KHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAV 307 Query: 332 -ASSASSFLDSDELERTGIDLGTTGRLQLMA-RLAEGTGLQIPPAAQQALQMSGSLAFGA 389 A++A++ + + E LGT G L++ L L P A A Q G + Sbjct: 308 AAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVT 367 Query: 390 VAEFSFVIDLQT------------------------------------RLSQQTEASALA 413 A + + + LS+Q S Sbjct: 368 PARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISG 427 Query: 414 AAAS-------VQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGV--IHIY 464 ++A ++ + L NM +P+ D +++ +V EEC K G V + IY Sbjct: 428 SSARHMVMQKLLRKQESTVMVLRNMVDPK-----DIDDDLEGEVTEECGKFGAVNRVIIY 482 Query: 465 VDKNSAQGN------VYVKCPSIAAAIAAVNALHGRWFAGKMITA 503 +K + + ++V+ + A+ AL+GRWFAG+ + A Sbjct: 483 QEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVA 527 Score = 75.5 bits (184), Expect = 1e-13 Identities = 40/98 (40%), Positives = 58/98 (59%) Query: 227 ASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSE 286 A Q ++ MA Q+ A R+YVGS+++ + ED +R F PFG I+SI + DS Sbjct: 89 AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148 Query: 287 TGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVG 324 T + KG+ F+ + E A+ ALEQ+N L GR +KVG Sbjct: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186 Score = 32.0 bits (71), Expect = 1.4 Identities = 14/65 (21%), Positives = 28/65 (43%) Query: 142 IDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201 ID L E R ++ + + D++ F GK++ + D + + KG ++E+ Sbjct: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257 Query: 202 VDVSS 206 S Sbjct: 258 EKAQS 262 >gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform a [Homo sapiens] Length = 475 Score = 89.4 bits (220), Expect = 8e-18 Identities = 108/522 (20%), Positives = 194/522 (37%), Gaps = 100/522 (19%) Query: 28 HEERSKKRKKSKSRSRSHERKRSKSKERK-RSRDRERKKSKSRERKRSRSKERRRSRSRS 86 +E + ++ K+++ R RSH R RS+ ++R+ RSRDR + +S R R R R + +R Sbjct: 12 NENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR---RSKPLTRG 68 Query: 87 RDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLT 146 G RSP K +R +P + K+ + P + +T Sbjct: 69 AKEEHGGLIRSPRHEKK--KKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMT 126 Query: 147 PE----------------ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDR-- 188 P+ R AR ++ + I + +FF+ ++ + Sbjct: 127 PDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPV 186 Query: 189 ---NSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKG 245 + K A++EF V A+ G G + ++ + M+ N Sbjct: 187 LAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVY 245 Query: 246 SAGPM---------RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFI 296 G + +L++G L + +D ++ + FG +++ L+ DS TG SKGY F Sbjct: 246 VPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305 Query: 297 TFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGR 356 + D +A+ LNG +L + + V + A +A+ + +T + Sbjct: 306 EYVDINVTDQAIAGLNGMQLGDKKLLVQRAS--VGAKNATLVSPPSTINQTPVT------ 357 Query: 357 LQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAA 416 LQ+P +QM G Sbjct: 358 ------------LQVPGLMSSQVQMGGH-------------------------------- 373 Query: 417 SVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKN------SA 470 T+ L NM P+ + EI +DV +EC+K+G V I + + Sbjct: 374 -----PTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPG 428 Query: 471 QGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYH 512 G ++V+ S+ A+ L GR FA +++ Y +YH Sbjct: 429 CGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYH 470 >gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform b [Homo sapiens] Length = 471 Score = 88.2 bits (217), Expect = 2e-17 Identities = 108/522 (20%), Positives = 196/522 (37%), Gaps = 104/522 (19%) Query: 28 HEERSKKRKKSKSRSRSHERKRSKSKERK-RSRDRERKKSKSRERKRSRSKERRRSRSRS 86 +E + ++ K+++ R RSH R RS+ ++R+ RSRDR + +S R R R R + +R Sbjct: 12 NENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR---RSKPLTRG 68 Query: 87 RDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLT 146 G RSP K +R +P + K+ + P + +T Sbjct: 69 AKEEHGGLIRSPRHEKK--KKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMT 126 Query: 147 PE----------------ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDR-- 188 P+ R AR ++ + I + +FF+ ++ + Sbjct: 127 PDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPV 186 Query: 189 ---NSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKG 245 + K A++EF V A+ G G + ++ + M+ N Sbjct: 187 LAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVY 245 Query: 246 SAGPM---------RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFI 296 G + +L++G L + +D ++ + FG +++ L+ DS TG SKGY F Sbjct: 246 VPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305 Query: 297 TFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGR 356 + D +A+ LNG +L + + V +R + ++ L + + +T + Sbjct: 306 EYVDINVTDQAIAGLNGMQLGDKKLLV----QRASVGAKNATLST--INQTPVT------ 353 Query: 357 LQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAA 416 LQ+P +QM G Sbjct: 354 ------------LQVPGLMSSQVQMGGH-------------------------------- 369 Query: 417 SVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKN------SA 470 T+ L NM P+ + EI +DV +EC+K+G V I + + Sbjct: 370 -----PTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPG 424 Query: 471 QGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYH 512 G ++V+ S+ A+ L GR FA +++ Y +YH Sbjct: 425 CGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYH 466 >gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo sapiens] Length = 370 Score = 87.4 bits (215), Expect = 3e-17 Identities = 53/178 (29%), Positives = 101/178 (56%), Gaps = 8/178 (4%) Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213 VF L I + L E FS GK+ +++SD + SKG A+V F + S+ AI + Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157 Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273 G+ + G + V + K+R A + + + + +Y+ + ++ ++ L+ +F + Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREAELRSKASEFT----NVYIKNFGGDMDDERLKDVFSKY 213 Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331 G+ S+++M DS +G+SKG+GF++F E AKKA+E++NG ++ G+ + VG ++ + Sbjct: 214 GKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVE 270 Score = 75.9 bits (185), Expect = 9e-14 Identities = 51/163 (31%), Positives = 87/163 (53%), Gaps = 12/163 (7%) Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-LTGQRVLGVPIIVQA 227 L++ FS GK V++++D +S +SKG +V F + A+ + G+ + G I V Sbjct: 206 LKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGR 264 Query: 228 SQAEKNRAAAMANNLQ-------KGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQ 280 +Q + R A + + +G G ++LY+ +L I ++ LR F FG I ++ Sbjct: 265 AQKKVERQAELKQMFEQLKRERIRGCQG-VKLYIKNLDDTIDDEKLRNEFSSFGSISRVK 323 Query: 281 LMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323 +M E G+SKG+G I FS E A KA+ ++NG L +P+ + Sbjct: 324 VMQ--EEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364 Score = 68.6 bits (166), Expect = 1e-11 Identities = 54/172 (31%), Positives = 84/172 (48%), Gaps = 18/172 (10%) Query: 173 FSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQASQAE 231 FSTVG V +R+ D+ +RRS G AYV F+ ++ A+ ++ G I + SQ + Sbjct: 30 FSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTMNFDIIKGKSIRLMWSQRD 89 Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291 L++ G +++ +L +I L F FG+I S ++M D + SK Sbjct: 90 A--------YLRRSGIG--NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQ--GSK 137 Query: 292 GYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD-----ASSASSF 338 GY F+ F + A +A+E++NG L G + VG R D S AS F Sbjct: 138 GYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEF 189 Score = 53.5 bits (127), Expect = 5e-07 Identities = 27/72 (37%), Positives = 43/72 (59%) Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311 LYVG LH ++TED+L F G + SI++ D T RS GY ++ F A+KAL+ + Sbjct: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71 Query: 312 NGFELAGRPMKV 323 N + G+ +++ Sbjct: 72 NFDIIKGKSIRL 83 >gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b [Homo sapiens] Length = 285 Score = 83.2 bits (204), Expect = 5e-16 Identities = 53/167 (31%), Positives = 87/167 (52%), Gaps = 13/167 (7%) Query: 144 NLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVD 203 N + E DA +F L+ +DL+++F+ G+V D + D N+ RS+G ++ F D Sbjct: 61 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120 Query: 204 VSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263 +SV + R+ G I + +A AM + K +++VG L+ TE Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167 Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310 + +R F FG IE+I+L MD + + +G+ FITF + E KK LE+ Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214 Score = 53.9 bits (128), Expect = 4e-07 Identities = 26/79 (32%), Positives = 42/79 (53%) Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291 +N A N K +++VG L ++ ++ L+ F FG + + MD TGRS+ Sbjct: 52 QNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSR 111 Query: 292 GYGFITFSDSECAKKALEQ 310 G+GFI F D+ +K L+Q Sbjct: 112 GFGFILFKDAASVEKVLDQ 130 >gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform a [Homo sapiens] Length = 332 Score = 83.2 bits (204), Expect = 5e-16 Identities = 53/167 (31%), Positives = 87/167 (52%), Gaps = 13/167 (7%) Query: 144 NLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVD 203 N + E DA +F L+ +DL+++F+ G+V D + D N+ RS+G ++ F D Sbjct: 61 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120 Query: 204 VSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263 +SV + R+ G I + +A AM + K +++VG L+ TE Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167 Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310 + +R F FG IE+I+L MD + + +G+ FITF + E KK LE+ Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214 Score = 53.9 bits (128), Expect = 4e-07 Identities = 26/79 (32%), Positives = 42/79 (53%) Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291 +N A N K +++VG L ++ ++ L+ F FG + + MD TGRS+ Sbjct: 52 QNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSR 111 Query: 292 GYGFITFSDSECAKKALEQ 310 G+GFI F D+ +K L+Q Sbjct: 112 GFGFILFKDAASVEKVLDQ 130 >gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo sapiens] Length = 375 Score = 83.2 bits (204), Expect = 5e-16 Identities = 52/122 (42%), Positives = 77/122 (63%), Gaps = 15/122 (12%) Query: 17 KDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKE-RKRSRDRERKKSKSRERK--R 73 K +L+S+ E+R K++++ SR RSH R RS+ + R RSR+R++ +S+SRERK R Sbjct: 38 KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 97 Query: 74 SRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRK 133 SRS+ER++SRSRSR+R+ R R RS R + H + SR R+RS+S RK Sbjct: 98 SRSRERKKSRSRSRERKRRIRSRS-----------RSRSRHRHRTR-SRSRTRSRSRDRK 145 Query: 134 DK 135 + Sbjct: 146 KR 147 Score = 77.0 bits (188), Expect = 4e-14 Identities = 48/121 (39%), Positives = 65/121 (53%), Gaps = 2/121 (1%) Query: 12 EAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRER 71 E +K+ E K S H + ++ +SRSR ++ RS+S+ERK+SR R R++ KSR R Sbjct: 50 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 109 Query: 72 KRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPF 131 R R K R RSRSRSR R R R RS + + +I P S R+ S PF Sbjct: 110 SRER-KRRIRSRSRSRSRH-RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 167 Query: 132 R 132 R Sbjct: 168 R 168 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/89 (42%), Positives = 54/89 (60%), Gaps = 10/89 (11%) Query: 16 KKDENKLSSANGHEERSKKRKKSKSRSRSHERK-------RSKSKERKRSRDRERKKSKS 68 ++ +++ S + RS+ R++ KSRSRS ERK RS+S+ R R+R R R +S+S Sbjct: 82 ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRS 141 Query: 69 RERKRSRSKERRRSRSRSRDRR---FRGR 94 R+RK+ K RR SRS SR FRGR Sbjct: 142 RDRKKRIEKPRRFSRSLSRTPSPPPFRGR 170 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/118 (33%), Positives = 57/118 (48%), Gaps = 7/118 (5%) Query: 22 LSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRR 81 L HE + K KK KS + +++ S K R+R E + + + ++R S+ R Sbjct: 8 LKQGRRHESKDKSSKKHKSEEHN-DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH 66 Query: 82 SRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVR 139 SRSRSR+RR R R R K S R + S SR R +S+S R+ K +R Sbjct: 67 SRSRSRERRHRSRSR---ERKKSRSRSRER---KKSRSRSRERKKSRSRSRERKRRIR 118 Score = 36.6 bits (83), Expect = 0.058 Identities = 21/74 (28%), Positives = 38/74 (51%) Query: 16 KKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSR 75 +K + S + R + R +S++RSRS +RK+ K R+ SR R S R R+ Sbjct: 113 RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 172 Query: 76 SKERRRSRSRSRDR 89 + + + + +R +R Sbjct: 173 AMDAQEALARRLER 186 Score = 33.5 bits (75), Expect = 0.49 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 4/64 (6%) Query: 19 ENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKE 78 E K + RS+ R +++SRSR+ RS+S++RK+ ++ R+ S+S R S Sbjct: 112 ERKRRIRSRSRSRSRHRHRTRSRSRT----RSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 167 Query: 79 RRRS 82 R R+ Sbjct: 168 RGRN 171 >gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo sapiens] Length = 434 Score = 83.2 bits (204), Expect = 5e-16 Identities = 52/122 (42%), Positives = 77/122 (63%), Gaps = 15/122 (12%) Query: 17 KDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKE-RKRSRDRERKKSKSRERK--R 73 K +L+S+ E+R K++++ SR RSH R RS+ + R RSR+R++ +S+SRERK R Sbjct: 97 KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 156 Query: 74 SRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRK 133 SRS+ER++SRSRSR+R+ R R RS R + H + SR R+RS+S RK Sbjct: 157 SRSRERKKSRSRSRERKRRIRSRS-----------RSRSRHRHRTR-SRSRTRSRSRDRK 204 Query: 134 DK 135 + Sbjct: 205 KR 206 Score = 77.0 bits (188), Expect = 4e-14 Identities = 48/121 (39%), Positives = 65/121 (53%), Gaps = 2/121 (1%) Query: 12 EAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRER 71 E +K+ E K S H + ++ +SRSR ++ RS+S+ERK+SR R R++ KSR R Sbjct: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168 Query: 72 KRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPF 131 R R K R RSRSRSR R R R RS + + +I P S R+ S PF Sbjct: 169 SRER-KRRIRSRSRSRSRH-RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 226 Query: 132 R 132 R Sbjct: 227 R 227 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/89 (42%), Positives = 54/89 (60%), Gaps = 10/89 (11%) Query: 16 KKDENKLSSANGHEERSKKRKKSKSRSRSHERK-------RSKSKERKRSRDRERKKSKS 68 ++ +++ S + RS+ R++ KSRSRS ERK RS+S+ R R+R R R +S+S Sbjct: 141 ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRS 200 Query: 69 RERKRSRSKERRRSRSRSRDRR---FRGR 94 R+RK+ K RR SRS SR FRGR Sbjct: 201 RDRKKRIEKPRRFSRSLSRTPSPPPFRGR 229 Score = 53.5 bits (127), Expect = 5e-07 Identities = 53/164 (32%), Positives = 70/164 (42%), Gaps = 47/164 (28%) Query: 17 KDENKLSSANGHEERSKKRKKSKSRSRSHERK------------RSKSKERKR--SRDRE 62 +D+ K S R+ K S+SRSRS ERK RS+SKE +R S+D+ Sbjct: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKS 79 Query: 63 RKKSKSRE---------------------------RKRSRSKERRRSRSRSRDRRFRGRY 95 KK KS E ++R S+ R SRSRSR+RR R R Sbjct: 80 SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRS 139 Query: 96 RSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVR 139 R K S R + S SR R +S+S R+ K +R Sbjct: 140 R---ERKKSRSRSRER---KKSRSRSRERKKSRSRSRERKRRIR 177 Score = 36.6 bits (83), Expect = 0.058 Identities = 21/74 (28%), Positives = 38/74 (51%) Query: 16 KKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSR 75 +K + S + R + R +S++RSRS +RK+ K R+ SR R S R R+ Sbjct: 172 RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 231 Query: 76 SKERRRSRSRSRDR 89 + + + + +R +R Sbjct: 232 AMDAQEALARRLER 245 Score = 33.5 bits (75), Expect = 0.49 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 4/64 (6%) Query: 19 ENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKE 78 E K + RS+ R +++SRSR+ RS+S++RK+ ++ R+ S+S R S Sbjct: 171 ERKRRIRSRSRSRSRHRHRTRSRSRT----RSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 226 Query: 79 RRRS 82 R R+ Sbjct: 227 RGRN 230 >gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo sapiens] Length = 420 Score = 82.8 bits (203), Expect = 7e-16 Identities = 53/166 (31%), Positives = 88/166 (53%), Gaps = 12/166 (7%) Query: 144 NLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVD 203 N + ++D +F L+ +DL E+ S G+V D + +D + RS+G +V F D Sbjct: 139 NASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKD 198 Query: 204 VSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263 +SV + L ++ G I + RA A+ KG P +++VG L + +E Sbjct: 199 AASVDKVLELKEHKLDGKLI-------DPKRAKAL-----KGKEPPKKVFVGGLSPDTSE 246 Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALE 309 + ++ F FG IE+I+L MD++T +G+ FIT++D E KK LE Sbjct: 247 EQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLE 292 >gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo sapiens] Length = 631 Score = 80.9 bits (198), Expect = 3e-15 Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 10/186 (5%) Query: 145 LTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDV 204 L + ++ V+ + L+E FS GK V+++ D N + SKG +V + Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGFVSYEKH 241 Query: 205 SSVPLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQK------GSAGPMRLYVGSL 257 A+ + G+ + G I V +Q + R A + ++ + LY+ +L Sbjct: 242 EDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNL 301 Query: 258 HFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELA 317 I ++ LR F PFG I S ++M+ E GRSKG+GF+ FS E A KA+ ++NG + Sbjct: 302 DDTIDDEKLRKEFSPFGSITSAKVML--EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVG 359 Query: 318 GRPMKV 323 +P+ V Sbjct: 360 SKPLYV 365 Score = 75.9 bits (185), Expect = 9e-14 Identities = 48/178 (26%), Positives = 92/178 (51%), Gaps = 8/178 (4%) Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213 VF L I + L + FS G + +++ D N SKG A+V F + AI + Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKM 158 Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273 G + + V ++ K R A + ++ + +Y+ + + ++ L+ +F F Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT----NVYIKNFGEEVDDESLKELFSQF 214 Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331 G+ S+++M D G+SKG+GF+++ E A KA+E++NG E++G+ + VG ++ + Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271 Score = 70.5 bits (171), Expect = 4e-12 Identities = 55/164 (33%), Positives = 79/164 (48%), Gaps = 13/164 (7%) Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQA 227 L E FS G V +R+ D +RRS G AYV F + A+ V+ G PI + Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86 Query: 228 SQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSET 287 SQ + +L+K G +++ +L +I L F FG I S +++ D E Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD-EN 135 Query: 288 GRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331 G SKGY F+ F E A KA+E++NG L R + VG R + Sbjct: 136 G-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKE 178 Score = 58.2 bits (139), Expect = 2e-08 Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Query: 246 SAGPMR-LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECA 304 S+ PM LYVG LH ++TE ML F P G + SI++ D T RS GY ++ F A Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65 Query: 305 KKALEQLNGFELAGRPMKV 323 ++AL+ +N + G+P+++ Sbjct: 66 ERALDTMNFDVIKGKPIRI 84 >gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo sapiens] Length = 644 Score = 80.9 bits (198), Expect = 3e-15 Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 10/186 (5%) Query: 145 LTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDV 204 L + ++ V+ + L+E FS GK V+++ D N + SKG +V + Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGFVSYEKH 241 Query: 205 SSVPLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQK------GSAGPMRLYVGSL 257 A+ + G+ + G I V +Q + R A + ++ + LY+ +L Sbjct: 242 EDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNL 301 Query: 258 HFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELA 317 I ++ LR F PFG I S ++M+ E GRSKG+GF+ FS E A KA+ ++NG + Sbjct: 302 DDTIDDEKLRKEFSPFGSITSAKVML--EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVG 359 Query: 318 GRPMKV 323 +P+ V Sbjct: 360 SKPLYV 365 Score = 75.9 bits (185), Expect = 9e-14 Identities = 48/178 (26%), Positives = 92/178 (51%), Gaps = 8/178 (4%) Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213 VF L I + L + FS G + +++ D N SKG A+V F + AI + Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKM 158 Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273 G + + V ++ K R A + ++ + +Y+ + + ++ L+ +F F Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT----NVYIKNFGEEVDDESLKELFSQF 214 Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331 G+ S+++M D G+SKG+GF+++ E A KA+E++NG E++G+ + VG ++ + Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271 Score = 70.5 bits (171), Expect = 4e-12 Identities = 55/164 (33%), Positives = 79/164 (48%), Gaps = 13/164 (7%) Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQA 227 L E FS G V +R+ D +RRS G AYV F + A+ V+ G PI + Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86 Query: 228 SQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSET 287 SQ + +L+K G +++ +L +I L F FG I S +++ D E Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD-EN 135 Query: 288 GRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331 G SKGY F+ F E A KA+E++NG L R + VG R + Sbjct: 136 G-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKE 178 Score = 58.2 bits (139), Expect = 2e-08 Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Query: 246 SAGPMR-LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECA 304 S+ PM LYVG LH ++TE ML F P G + SI++ D T RS GY ++ F A Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65 Query: 305 KKALEQLNGFELAGRPMKV 323 ++AL+ +N + G+P+++ Sbjct: 66 ERALDTMNFDVIKGKPIRI 84 >gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo sapiens] Length = 660 Score = 80.9 bits (198), Expect = 3e-15 Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 10/186 (5%) Query: 145 LTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDV 204 L + ++ V+ + L+E FS GK V+++ D N + SKG +V + Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGFVSYEKH 241 Query: 205 SSVPLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQK------GSAGPMRLYVGSL 257 A+ + G+ + G I V +Q + R A + ++ + LY+ +L Sbjct: 242 EDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNL 301 Query: 258 HFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELA 317 I ++ LR F PFG I S ++M+ E GRSKG+GF+ FS E A KA+ ++NG + Sbjct: 302 DDTIDDEKLRKEFSPFGSITSAKVML--EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVG 359 Query: 318 GRPMKV 323 +P+ V Sbjct: 360 SKPLYV 365 Score = 75.9 bits (185), Expect = 9e-14 Identities = 48/178 (26%), Positives = 92/178 (51%), Gaps = 8/178 (4%) Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213 VF L I + L + FS G + +++ D N SKG A+V F + AI + Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKM 158 Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273 G + + V ++ K R A + ++ + +Y+ + + ++ L+ +F F Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT----NVYIKNFGEEVDDESLKELFSQF 214 Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331 G+ S+++M D G+SKG+GF+++ E A KA+E++NG E++G+ + VG ++ + Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271 Score = 70.5 bits (171), Expect = 4e-12 Identities = 55/164 (33%), Positives = 79/164 (48%), Gaps = 13/164 (7%) Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQA 227 L E FS G V +R+ D +RRS G AYV F + A+ V+ G PI + Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86 Query: 228 SQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSET 287 SQ + +L+K G +++ +L +I L F FG I S +++ D E Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD-EN 135 Query: 288 GRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331 G SKGY F+ F E A KA+E++NG L R + VG R + Sbjct: 136 G-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKE 178 Score = 58.2 bits (139), Expect = 2e-08 Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Query: 246 SAGPMR-LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECA 304 S+ PM LYVG LH ++TE ML F P G + SI++ D T RS GY ++ F A Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65 Query: 305 KKALEQLNGFELAGRPMKV 323 ++AL+ +N + G+P+++ Sbjct: 66 ERALDTMNFDVIKGKPIRI 84 >gi|20373175 musashi 2 isoform a [Homo sapiens] Length = 328 Score = 80.5 bits (197), Expect = 4e-15 Identities = 46/161 (28%), Positives = 79/161 (49%), Gaps = 8/161 (4%) Query: 149 ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVP 208 + D +F L+ + P L ++FS G++R+ ++ D ++RS+G +V F D +SV Sbjct: 17 QHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV- 75 Query: 209 LAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRG 268 +VLG P S+ + A K +++VG L N + ++ Sbjct: 76 -------DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQ 128 Query: 269 IFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALE 309 FE FG++E LM D T R +G+GF+TF + + +K E Sbjct: 129 YFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 169 Score = 55.5 bits (132), Expect = 1e-07 Identities = 26/80 (32%), Positives = 40/80 (50%) Query: 231 EKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRS 290 E N + + + P ++++G L + + D LR F FG I +M D T RS Sbjct: 2 EANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRS 61 Query: 291 KGYGFITFSDSECAKKALEQ 310 +G+GF+TF+D K L Q Sbjct: 62 RGFGFVTFADPASVDKVLGQ 81 >gi|188219591 TIA1 protein isoform 2 [Homo sapiens] Length = 386 Score = 79.7 bits (195), Expect = 6e-15 Identities = 50/194 (25%), Positives = 101/194 (52%), Gaps = 8/194 (4%) Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207 E+ +T++ L+ + + + FS +G ++ +MI D + + +VEF + Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59 Query: 208 PLAIG-LTGQRVLGVPIIVQ----ASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNIT 262 A+ + G++++G + V S +K+ +++ + Q+ S ++VG L IT Sbjct: 60 AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQR-SQDHFHVFVGDLSPEIT 118 Query: 263 EDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322 + ++ F PFGRI +++ D TG+SKGYGF++F + A+ A++Q+ G L GR ++ Sbjct: 119 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 178 Query: 323 VGHVTERTDASSAS 336 T + A ++ Sbjct: 179 TNWATRKPPAPKST 192 Score = 72.0 bits (175), Expect = 1e-12 Identities = 48/188 (25%), Positives = 83/188 (44%), Gaps = 17/188 (9%) Query: 146 TPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVS 205 T +D VF L+ I D++ F+ G++ D R++ D + +SKG +V F + Sbjct: 99 TQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKW 158 Query: 206 SVPLAIGLTGQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYV 254 AI G + LG P +++ + + + + S +Y Sbjct: 159 DAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYC 218 Query: 255 GSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGF 314 G + +TE ++R F PFG+I I++ D KGY F+ F+ E A A+ +NG Sbjct: 219 GGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGT 272 Query: 315 ELAGRPMK 322 + G +K Sbjct: 273 TIEGHVVK 280 >gi|188219593 TIA1 protein isoform 1 [Homo sapiens] Length = 375 Score = 79.3 bits (194), Expect = 8e-15 Identities = 48/190 (25%), Positives = 97/190 (51%), Gaps = 11/190 (5%) Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207 E+ +T++ L+ + + + FS +G ++ +MI D + + +VEF + Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59 Query: 208 PLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266 A+ + G++++G + K A ++ +K ++ ++VG L IT + + Sbjct: 60 AAALAAMNGRKIMGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 111 Query: 267 RGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHV 326 + F PFGRI +++ D TG+SKGYGF++F + A+ A++Q+ G L GR ++ Sbjct: 112 KAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWA 171 Query: 327 TERTDASSAS 336 T + A ++ Sbjct: 172 TRKPPAPKST 181 Score = 70.5 bits (171), Expect = 4e-12 Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 17/179 (9%) Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214 VF L+ I D++ F+ G++ D R++ D + +SKG +V F + AI Sbjct: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156 Query: 215 GQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263 G + LG P +++ + + + + S +Y G + +TE Sbjct: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216 Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322 ++R F PFG+I I++ D KGY F+ F+ E A A+ +NG + G +K Sbjct: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 79.3 bits (194), Expect = 8e-15 Identities = 56/184 (30%), Positives = 90/184 (48%), Gaps = 13/184 (7%) Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207 E TV+ L ++ L E F G V + M DR + + +G +VEF+ Sbjct: 8 ERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDA 67 Query: 208 PLAIGLTGQ-RVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266 AI + ++ G PI V N+A+A NL G+ +++G+L I E +L Sbjct: 68 DYAIKIMNMIKLYGKPIRV-------NKASAHNKNLDVGA----NIFIGNLDPEIDEKLL 116 Query: 267 RGIFEPFGRI-ESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGH 325 F FG I ++ ++M D +TG SKGY FI F+ + + A+E +NG L RP+ V + Sbjct: 117 YDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSY 176 Query: 326 VTER 329 ++ Sbjct: 177 AFKK 180 >gi|25121993 musashi 2 isoform b [Homo sapiens] Length = 251 Score = 79.0 bits (193), Expect = 1e-14 Identities = 45/155 (29%), Positives = 77/155 (49%), Gaps = 8/155 (5%) Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214 +F L+ + P L ++FS G++R+ ++ D ++RS+G +V F D +SV Sbjct: 19 MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV------- 71 Query: 215 GQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFG 274 +VLG P S+ + A K +++VG L N + ++ FE FG Sbjct: 72 -DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFG 130 Query: 275 RIESIQLMMDSETGRSKGYGFITFSDSECAKKALE 309 ++E LM D T R +G+GF+TF + + +K E Sbjct: 131 KVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 165 Score = 52.4 bits (124), Expect = 1e-06 Identities = 23/60 (38%), Positives = 34/60 (56%) Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310 ++++G L + + D LR F FG I +M D T RS+G+GF+TF+D K L Q Sbjct: 18 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 77 Score = 34.7 bits (78), Expect = 0.22 Identities = 14/49 (28%), Positives = 27/49 (55%) Query: 153 RTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201 + +F L+A D++++F GKV D ++ D+ + R +G +V F Sbjct: 106 KKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTF 154 >gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] Length = 288 Score = 78.6 bits (192), Expect = 1e-14 Identities = 65/195 (33%), Positives = 90/195 (46%), Gaps = 33/195 (16%) Query: 12 EAPYKKDENKLSSANGHEERS-KKRKKSKSRSRSHE-RKRSKSKERKRSRDRERKKSKSR 69 E Y + E++ +S +G S K + + +RSRS E +RS+SK R RS R R + SR Sbjct: 6 EQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSR 65 Query: 70 ERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKS 129 R +RS+ R RS RSR R + YR RR S S S Sbjct: 66 -RHYTRSRSRSRSHRRSRSRSYSRDYR-------------------------RRHSHSHS 99 Query: 130 PFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRN 189 P + R + P+ VF + L RDL E FS G + DV ++ D+ Sbjct: 100 PMSTRR---RHVGNRANPDPNCCLGVFGLSLYT--TERDLREVFSKYGPIADVSIVYDQQ 154 Query: 190 SRRSKGIAYVEFVDV 204 SRRS+G A+V F +V Sbjct: 155 SRRSRGFAFVYFENV 169 Score = 53.5 bits (127), Expect = 5e-07 Identities = 27/72 (37%), Positives = 43/72 (59%) Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311 L V L TE LR +F +G I + ++ D ++ RS+G+ F+ F + + AK+A E+ Sbjct: 120 LGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERA 179 Query: 312 NGFELAGRPMKV 323 NG EL GR ++V Sbjct: 180 NGMELDGRRIRV 191 >gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] Length = 375 Score = 77.8 bits (190), Expect = 2e-14 Identities = 48/198 (24%), Positives = 99/198 (50%), Gaps = 11/198 (5%) Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207 ++ RT++ L+ + + + FS +G + +MI++ S + +VEF + Sbjct: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDA 61 Query: 208 PLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266 A+ + G+++LG + K A ++ +K ++ ++VG L IT + + Sbjct: 62 AAALAAMNGRKILGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 113 Query: 267 RGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHV 326 + F PFG+I +++ D TG+SKGYGF++F + A+ A+ + G L GR ++ Sbjct: 114 KSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWA 173 Query: 327 TERTDASSASSFLDSDEL 344 T + A ++ ++ +L Sbjct: 174 TRKPPAPKSTQENNTKQL 191 Score = 72.4 bits (176), Expect = 1e-12 Identities = 58/231 (25%), Positives = 98/231 (42%), Gaps = 23/231 (9%) Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214 VF L+ I D++ F+ GK+ D R++ D + +SKG +V F + AI Sbjct: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158 Query: 215 GQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263 G + LG P +++Q + + + + S +Y G + +T+ Sbjct: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218 Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323 ++R F PFG+I I++ + KGY F+ FS E A A+ +NG + G +K Sbjct: 219 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKC 272 Query: 324 GHVTERTDASSASSFLDSDELERTGIDLGTTGRL-QLMARLAEGTGLQIPP 373 E D + +D + + G + Q MA G Q+PP Sbjct: 273 YWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMA-----NGWQVPP 318 >gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform B1 [Homo sapiens] Length = 353 Score = 76.6 bits (187), Expect = 5e-14 Identities = 45/171 (26%), Positives = 85/171 (49%), Gaps = 8/171 (4%) Query: 141 PIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVE 200 P++ E+ R +F L+ L ++ GK+ D ++ D S+RS+G +V Sbjct: 9 PLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVT 68 Query: 201 FVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMR-LYVGSLHF 259 F ++ V A+ P + E RA A + + G+ ++ L+VG + Sbjct: 69 FSSMAEVDAAMAAR-------PHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKE 121 Query: 260 NITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310 + E LR FE +G+I++I+++ D ++G+ +G+GF+TF D + K + Q Sbjct: 122 DTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQ 172 >gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] Length = 631 Score = 76.3 bits (186), Expect = 7e-14 Identities = 56/185 (30%), Positives = 95/185 (51%), Gaps = 13/185 (7%) Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-LTGQRVLGVPIIVQA 227 L++ F G V++++D S +SKG +V F A+ + G+ + G I V Sbjct: 207 LKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGR 265 Query: 228 SQAEKNRAAAMANNLQKGSAGPM------RLYVGSLHFNITEDMLRGIFEPFGRIESIQL 281 +Q + R + ++ + LYV +L I ++ LR F PFG I S ++ Sbjct: 266 AQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKV 325 Query: 282 MMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDS 341 MM E GRSKG+GF+ FS E A KA+ ++NG +A +P+ V + +R + A +L + Sbjct: 326 MM--EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVA-LAQRKEERQA--YLTN 380 Query: 342 DELER 346 + ++R Sbjct: 381 EYMQR 385 Score = 74.3 bits (181), Expect = 3e-13 Identities = 52/194 (26%), Positives = 97/194 (50%), Gaps = 16/194 (8%) Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213 +F L I + L + S G + ++ D N SKG +V F + AI + Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG--SKGYGFVHFETHEAAERAIKKM 158 Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273 G + G + V ++ K R A + ++ +Y+ + ++ ++ L+ +F F Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREAELGARAKEFP----NVYIKNFGEDMDDERLKDLFGKF 214 Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDAS 333 G S+++M D E+G+SKG+GF++F E A+KA++++NG EL G+ + VG ++ + Sbjct: 215 GPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQ 273 Query: 334 SASSFLDSDELERT 347 + EL+RT Sbjct: 274 T--------ELKRT 279 Score = 53.9 bits (128), Expect = 4e-07 Identities = 27/72 (37%), Positives = 43/72 (59%) Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311 LYVG LH ++TE ML F P G I SI++ D T S Y ++ F ++ A+ AL+ + Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72 Query: 312 NGFELAGRPMKV 323 N + G+P+++ Sbjct: 73 NFDVIKGKPVRI 84 >gi|52426743 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 75.9 bits (185), Expect = 9e-14 Identities = 52/142 (36%), Positives = 80/142 (56%), Gaps = 7/142 (4%) Query: 16 KKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSR 75 +++E + A E R + R +S+ SR+ +R+ S+S++ KRSR RER++S+SR+R+RSR Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334 Query: 76 SKER--RRSRSRSRD-RRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFR 132 S +R R+ RSRSRD RR + R R Y K S R + S + +R S K Sbjct: 335 SHDRSERKHRSRSRDRRRSKSRDRKSY---KHRSKSRDREQDRKSKEKEKRGSDDKKSSV 391 Query: 133 KDKSPVREPID-NLTPEERDAR 153 K S ++ D N +E D + Sbjct: 392 KSGSREKQSEDTNTESKESDTK 413 Score = 72.8 bits (177), Expect = 7e-13 Identities = 48/137 (35%), Positives = 74/137 (54%), Gaps = 14/137 (10%) Query: 12 EAPYKKDENKLSSANGHEERSKKR---KKSKSRSRSHERKRSKSKERKRSRDRERKKSKS 68 E +++E + EER K+R ++ + RSRS R S++ +R+ SR R+ K+S+S Sbjct: 260 EREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRS 319 Query: 69 RERKRSRSKERRRSRSRSR-DRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRS 127 RER+RSRS++RRRSRS R +R+ R R R + S R + H R +SR Sbjct: 320 RERRRSRSRDRRRSRSHDRSERKHRSRSRD-----RRRSKSRDRKSYKH-----RSKSRD 369 Query: 128 KSPFRKDKSPVREPIDN 144 + RK K + D+ Sbjct: 370 REQDRKSKEKEKRGSDD 386 Score = 60.1 bits (144), Expect = 5e-09 Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 2/109 (1%) Query: 25 ANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRRSRS 84 A E + K RK+++ R K+ K + +R ++RER++ + ++R +ER + R+ Sbjct: 225 ATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERA 284 Query: 85 RSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRK 133 R R+RR R R RS +S S R H SR R RS+S R+ Sbjct: 285 RDRERRKRSRSRSRHSSR--TSDRRCSRSRDHKRSRSRERRRSRSRDRR 331 Score = 55.8 bits (133), Expect = 9e-08 Identities = 49/161 (30%), Positives = 81/161 (50%), Gaps = 15/161 (9%) Query: 7 IEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKS 66 I+A +E +K + + E K++++ + R + ER+R + + ++R + ER+K Sbjct: 223 IKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKE 282 Query: 67 KSRE---RKRSRSKERRRSR------SRSRD-RRFRGR-YRSPYSGPKFNSAIRGKIGLP 115 ++R+ RKRSRS+ R SR SRSRD +R R R R S + S + Sbjct: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342 Query: 116 HSIKLSRRRSRSKSPFRKD---KSPVREPIDNLTPEERDAR 153 H + SR R RSKS RK +S R+ + +E++ R Sbjct: 343 HRSR-SRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKR 382 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.130 0.364 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,753,423 Number of Sequences: 37866 Number of extensions: 760464 Number of successful extensions: 22008 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 679 Number of HSP's successfully gapped in prelim test: 295 Number of HSP's that attempted gapping in prelim test: 6501 Number of HSP's gapped (non-prelim): 6450 length of query: 530 length of database: 18,247,518 effective HSP length: 107 effective length of query: 423 effective length of database: 14,195,856 effective search space: 6004847088 effective search space used: 6004847088 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.