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Search of human proteins with 34577057
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34577057 fibronectin leucine rich transmembrane protein 1
[Homo sapiens]
(674 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho... 1352 0.0
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre... 740 0.0
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec... 740 0.0
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom... 541 e-153
gi|41350214 asporin [Homo sapiens] 135 1e-31
gi|51317373 netrin-G1 ligand [Homo sapiens] 134 4e-31
gi|198041768 synleurin [Homo sapiens] 130 4e-30
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s... 126 6e-29
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa... 126 6e-29
gi|45505137 podocan [Homo sapiens] 126 7e-29
gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 125 2e-28
gi|15029530 leucine rich repeat containing 4 [Homo sapiens] 122 1e-27
gi|19743846 decorin isoform a preproprotein [Homo sapiens] 121 2e-27
gi|4503271 decorin isoform a preproprotein [Homo sapiens] 121 2e-27
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] 120 3e-27
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] 120 3e-27
gi|71040111 fibromodulin precursor [Homo sapiens] 119 7e-27
gi|4502403 biglycan preproprotein [Homo sapiens] 118 2e-26
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens] 116 6e-26
gi|156139147 leucine rich repeat transmembrane neuronal 4 isofor... 113 5e-25
gi|197927168 leucine rich repeat transmembrane neuronal 4 isofor... 113 5e-25
gi|5901992 keratocan [Homo sapiens] 112 9e-25
gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens] 110 3e-24
gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens] 110 3e-24
gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens] 110 3e-24
gi|4826876 osteomodulin [Homo sapiens] 108 2e-23
gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ... 107 5e-23
gi|153251229 chondroadherin precursor [Homo sapiens] 106 6e-23
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 105 2e-22
gi|229089140 leucine rich repeat containing 24 [Homo sapiens] 104 2e-22
>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
sapiens]
Length = 674
Score = 1352 bits (3498), Expect = 0.0
Identities = 674/674 (100%), Positives = 674/674 (100%)
Query: 1 MVVAHPTATATTTPTATVTATVVMTTATMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRC 60
MVVAHPTATATTTPTATVTATVVMTTATMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRC
Sbjct: 1 MVVAHPTATATTTPTATVTATVVMTTATMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRC 60
Query: 61 DNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDE 120
DNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDE
Sbjct: 61 DNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDE 120
Query: 121 FPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLK 180
FPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLK
Sbjct: 121 FPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLK 180
Query: 181 LLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIA 240
LLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIA
Sbjct: 181 LLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIA 240
Query: 241 DDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLD 300
DDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLD
Sbjct: 241 DDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLD 300
Query: 301 LSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGP 360
LSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGP
Sbjct: 301 LSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGP 360
Query: 361 EKVRGMAIKDITSEMDECFETGPQGGVANAAAKTTASNHASATTPQGSLFTLKAKRPGLR 420
EKVRGMAIKDITSEMDECFETGPQGGVANAAAKTTASNHASATTPQGSLFTLKAKRPGLR
Sbjct: 361 EKVRGMAIKDITSEMDECFETGPQGGVANAAAKTTASNHASATTPQGSLFTLKAKRPGLR 420
Query: 421 LPDSNIDYPMATGDGAKTLAIHVKALTADSIRITWKATLPASSFRLSWLRLGHSPAVGSI 480
LPDSNIDYPMATGDGAKTLAIHVKALTADSIRITWKATLPASSFRLSWLRLGHSPAVGSI
Sbjct: 421 LPDSNIDYPMATGDGAKTLAIHVKALTADSIRITWKATLPASSFRLSWLRLGHSPAVGSI 480
Query: 481 TETLVQGDKTEYLLTALEPKSTYIICMVTMETSNAYVADETPVCAKAETADSYGPTTTLN 540
TETLVQGDKTEYLLTALEPKSTYIICMVTMETSNAYVADETPVCAKAETADSYGPTTTLN
Sbjct: 481 TETLVQGDKTEYLLTALEPKSTYIICMVTMETSNAYVADETPVCAKAETADSYGPTTTLN 540
Query: 541 QEQNAGPMASLPLAGIIGGAVALVFLFLVLGAICWYVHQAGELLTRERAYNRGSRKKDDY 600
QEQNAGPMASLPLAGIIGGAVALVFLFLVLGAICWYVHQAGELLTRERAYNRGSRKKDDY
Sbjct: 541 QEQNAGPMASLPLAGIIGGAVALVFLFLVLGAICWYVHQAGELLTRERAYNRGSRKKDDY 600
Query: 601 MESGTKKDNSILEIRGPGLQMLPINPYRAKEEYVVHTIFPSNGSSLCKATHTIGYGTTRG 660
MESGTKKDNSILEIRGPGLQMLPINPYRAKEEYVVHTIFPSNGSSLCKATHTIGYGTTRG
Sbjct: 601 MESGTKKDNSILEIRGPGLQMLPINPYRAKEEYVVHTIFPSNGSSLCKATHTIGYGTTRG 660
Query: 661 YRDGGIPDIDYSYT 674
YRDGGIPDIDYSYT
Sbjct: 661 YRDGGIPDIDYSYT 674
>gi|38202222 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 740 bits (1911), Expect = 0.0
Identities = 377/627 (60%), Positives = 466/627 (74%), Gaps = 12/627 (1%)
Query: 53 TCPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIY 112
+CPSVCRCD GFIYCNDR LTSIP IP+DATTLYLQNNQINNAGIP DLK + V+ IY
Sbjct: 30 SCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIY 89
Query: 113 LYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDA 172
LY N LDEFP NLP+ ++ELHLQ+NN+RTI DSL++IP LE+LHLDDNSVS VSIEE A
Sbjct: 90 LYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGA 149
Query: 173 FADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGN 232
F DS L+LLFLSRNHLS+IP GLP T+EELRLDDNRISTI + +GL SL+RLVLDGN
Sbjct: 150 FRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGN 209
Query: 233 LLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAK 292
LL N + D F L NLTELSLVRNSL A P+NLP +L+KLYLQDN I+ +P N +
Sbjct: 210 LLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSY 269
Query: 293 MRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNV 352
+R+L RLD+SNNNL+ LP+G+FDDL N+ QL+LRNNPW+CGC + W+RDW+++ VNV
Sbjct: 270 LRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNV 329
Query: 353 RGLMCQGPEKVRGMAIKDITSEMDECFETGPQGGVANAAAKTTASNHASATTPQGSLFTL 412
RGLMCQ PEKVRGMAIKD+ +E+ +C ++ G+ + TTA + + QG
Sbjct: 330 RGLMCQAPEKVRGMAIKDLNAELFDCKDS----GIVSTIQITTAIPN-TVYPAQGQWPAP 384
Query: 413 KAKRPGLRLPDSNIDYPMATGDGAKTLAIHVKALTADSIRITWKATLPASSFRLSWLRLG 472
K+P ++ P D+ KT+ I VK++T+D+I I+WK LP ++ RLSWL+LG
Sbjct: 385 VTKQPDIKNPKLTKDHQTTGSPSRKTITITVKSVTSDTIHISWKLALPMTALRLSWLKLG 444
Query: 473 HSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMVTMETSNAYVADETPVCAKAETAD- 531
HSPA GSITET+V G+++EYL+TALEP S Y +CMV METSN Y+ DETPVC + ETA
Sbjct: 445 HSPAFGSITETIVTGERSEYLVTALEPDSPYKVCMVPMETSNLYLFDETPVCIETETAPL 504
Query: 532 -SYGPTTTLNQEQNAGPM--ASLPLAGIIGGAVALVFLFLVLGAICWYVHQAGELLTRER 588
Y PTTTLN+EQ P +LPLA IIGGAVALV + L L +CWYVH+ G L +R
Sbjct: 505 RMYNPTTTLNREQEKEPYKNPNLPLAAIIGGAVALVTIAL-LALVCWYVHRNGSLFSRNC 563
Query: 589 AYNRGSRKKDDYMESGTKKDNSILEIRGPGLQMLPI-NPYRAKEEYVVHTIFPSNGSSLC 647
AY++G R+KDDY E+GTKKDNSILEIR QMLPI N +KEE+V+HTIFP NG +L
Sbjct: 564 AYSKGRRRKDDYAEAGTKKDNSILEIRETSFQMLPISNEPISKEEFVIHTIFPPNGMNLY 623
Query: 648 KATHTIGYGTTRGYRDGGIPDIDYSYT 674
K H+ + R YRD GIPD D+S++
Sbjct: 624 KNNHSES-SSNRSYRDSGIPDSDHSHS 649
>gi|7019383 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 740 bits (1911), Expect = 0.0
Identities = 377/627 (60%), Positives = 466/627 (74%), Gaps = 12/627 (1%)
Query: 53 TCPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIY 112
+CPSVCRCD GFIYCNDR LTSIP IP+DATTLYLQNNQINNAGIP DLK + V+ IY
Sbjct: 30 SCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIY 89
Query: 113 LYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDA 172
LY N LDEFP NLP+ ++ELHLQ+NN+RTI DSL++IP LE+LHLDDNSVS VSIEE A
Sbjct: 90 LYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGA 149
Query: 173 FADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGN 232
F DS L+LLFLSRNHLS+IP GLP T+EELRLDDNRISTI + +GL SL+RLVLDGN
Sbjct: 150 FRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGN 209
Query: 233 LLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAK 292
LL N + D F L NLTELSLVRNSL A P+NLP +L+KLYLQDN I+ +P N +
Sbjct: 210 LLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSY 269
Query: 293 MRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNV 352
+R+L RLD+SNNNL+ LP+G+FDDL N+ QL+LRNNPW+CGC + W+RDW+++ VNV
Sbjct: 270 LRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNV 329
Query: 353 RGLMCQGPEKVRGMAIKDITSEMDECFETGPQGGVANAAAKTTASNHASATTPQGSLFTL 412
RGLMCQ PEKVRGMAIKD+ +E+ +C ++ G+ + TTA + + QG
Sbjct: 330 RGLMCQAPEKVRGMAIKDLNAELFDCKDS----GIVSTIQITTAIPN-TVYPAQGQWPAP 384
Query: 413 KAKRPGLRLPDSNIDYPMATGDGAKTLAIHVKALTADSIRITWKATLPASSFRLSWLRLG 472
K+P ++ P D+ KT+ I VK++T+D+I I+WK LP ++ RLSWL+LG
Sbjct: 385 VTKQPDIKNPKLTKDHQTTGSPSRKTITITVKSVTSDTIHISWKLALPMTALRLSWLKLG 444
Query: 473 HSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMVTMETSNAYVADETPVCAKAETAD- 531
HSPA GSITET+V G+++EYL+TALEP S Y +CMV METSN Y+ DETPVC + ETA
Sbjct: 445 HSPAFGSITETIVTGERSEYLVTALEPDSPYKVCMVPMETSNLYLFDETPVCIETETAPL 504
Query: 532 -SYGPTTTLNQEQNAGPM--ASLPLAGIIGGAVALVFLFLVLGAICWYVHQAGELLTRER 588
Y PTTTLN+EQ P +LPLA IIGGAVALV + L L +CWYVH+ G L +R
Sbjct: 505 RMYNPTTTLNREQEKEPYKNPNLPLAAIIGGAVALVTIAL-LALVCWYVHRNGSLFSRNC 563
Query: 589 AYNRGSRKKDDYMESGTKKDNSILEIRGPGLQMLPI-NPYRAKEEYVVHTIFPSNGSSLC 647
AY++G R+KDDY E+GTKKDNSILEIR QMLPI N +KEE+V+HTIFP NG +L
Sbjct: 564 AYSKGRRRKDDYAEAGTKKDNSILEIRETSFQMLPISNEPISKEEFVIHTIFPPNGMNLY 623
Query: 648 KATHTIGYGTTRGYRDGGIPDIDYSYT 674
K H+ + R YRD GIPD D+S++
Sbjct: 624 KNNHSES-SSNRSYRDSGIPDSDHSHS 649
>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
sapiens]
Length = 660
Score = 541 bits (1393), Expect = e-153
Identities = 290/669 (43%), Positives = 416/669 (62%), Gaps = 49/669 (7%)
Query: 31 LRDWLFLCYGLIAFLTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQN 90
L+ WL + GL + +++++ CPSVCRCD F+YCN+R LTS+P IP+ T LYL N
Sbjct: 16 LKSWLIISLGLYSQVSKLL---ACPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHN 72
Query: 91 NQINNAGIPQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARI 150
NQINNAG P +L +V +YLY N LDEFP+NLP+++R LHLQ+NN++TI+R +LA++
Sbjct: 73 NQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQL 132
Query: 151 PLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRI 210
LE+LHLDDNS+STV +E+ AF ++ LKLLFLS+NHLSS+P GLP L+ELR+D+NRI
Sbjct: 133 LKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRI 192
Query: 211 STIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSA 270
+ I AF+ L SL RL++DGNLL N+ IA+ TFS L L E S+VRNSL+ PP +LP
Sbjct: 193 AVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGT 252
Query: 271 HLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPW 330
HL +LYLQDN I+HIP + +R+LERLD+SNN L L +G+FD+L NL QL RNNPW
Sbjct: 253 HLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNNPW 312
Query: 331 FCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFETGPQGGVANA 390
FC C++ W+ +W+K + +NVRG MCQGPE+VRGMA++++ + C T P
Sbjct: 313 FCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTTTP-----GL 367
Query: 391 AAKTTASNHASATTPQGSLFTLKAKRPGLRLPDSNIDYPMAT-----------GDG---- 435
T A + AS TT + P L +P+ + Y T DG
Sbjct: 368 PLFTPAPSTASPTT----------QPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERV 417
Query: 436 ----AKTLAIHVKALTADSIRITWKATLPASSFRLSWLRLGHSPAVGSITETLVQGDKTE 491
++ + + + + SI+++W + +++L+W+++GHS G + E +V G+K
Sbjct: 418 TPPISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQH 477
Query: 492 YLLTALEPKSTYIICMVTMETSNAYVADETPVCAKAETADSY---GPTTTLNQEQNAGPM 548
L LEP+STY IC+V ++ N Y A E +C++A T SY G T + EQ
Sbjct: 478 LSLVNLEPRSTYRICLVPLDAFN-YRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHS 536
Query: 549 ASLP--LAGIIGGAVALVFLFLVLGAICWYVHQAGELLTRERAYNRGSRKKDDYMESGTK 606
P LAG+IGGAV V L ++L CW++H+ G +++ YNRG R+KDDY E+GTK
Sbjct: 537 MGSPFLLAGLIGGAVIFV-LVVLLSVFCWHMHKKGRYTSQKWKYNRG-RRKDDYCEAGTK 594
Query: 607 KDNSILEIRGPGLQMLPI-NPYRAKEEYVVHTIFPSNGSSLCKATHTIGYGTTRGYRDGG 665
KDNSILE+ Q++ + N K ++ + I+ NG H Y +
Sbjct: 595 KDNSILEMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCH---IPNNMRYCNSS 651
Query: 666 IPDIDYSYT 674
+PD+++ +T
Sbjct: 652 VPDLEHCHT 660
>gi|41350214 asporin [Homo sapiens]
Length = 380
Score = 135 bits (340), Expect = 1e-31
Identities = 92/281 (32%), Positives = 143/281 (50%), Gaps = 33/281 (11%)
Query: 54 CPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQI-------------------N 94
CP C+C + ++C+D GLTS+P +IP D L LQNN+I N
Sbjct: 75 CPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILN 134
Query: 95 NAGI----PQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARI 150
N + P+ T ++ +YL N L E P+NLP+SL EL + +N V+ I +D+ +
Sbjct: 135 NNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGM 194
Query: 151 PLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRI 210
L L + N + IE AF + + + ++ L+S+P GLP TL EL LD N+I
Sbjct: 195 NALHVLEMSANPLDNNGIEPGAF-EGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKI 253
Query: 211 STIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPS- 269
ST+ L FK L+RL L N + + I + + + + + E+ L N L P LP
Sbjct: 254 STVELEDFKRYKELQRLGLGNNKITD--IENGSLANIPRVREIHLENNKLKKIPSGLPEL 311
Query: 270 AHLQKLYLQDNAISHIPYN----TLAKMRE--LERLDLSNN 304
+LQ ++L N+I+ + N T+ KM++ + L NN
Sbjct: 312 KYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNN 352
>gi|51317373 netrin-G1 ligand [Homo sapiens]
Length = 640
Score = 134 bits (336), Expect = 4e-31
Identities = 117/408 (28%), Positives = 182/408 (44%), Gaps = 54/408 (13%)
Query: 48 VIDSTTCPSVCRCDNGF--IYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTK 105
++ + TCPSVC C N F + C + L +P I
Sbjct: 41 LVRAQTCPSVCSCSNQFSKVICVRKNLREVPDGI-------------------------S 75
Query: 106 VNVQVIYLYENDLDEFPINLPRSLRELH---LQDNNVRTIARDSLARIPLLEKLHLDDNS 162
N +++ L+EN + +N + LR L L N++RTI + + L L L DN
Sbjct: 76 TNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNR 135
Query: 163 VSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDD----NRISTIPLHAF 218
++T I AF +LK L+L N + SIPS + + LR D R+S I AF
Sbjct: 136 LTT--IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAF 193
Query: 219 KGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAA--PPLNLPSAHLQKLY 276
+GL++LR L L + N R + + L L EL L N L+A P HLQKL+
Sbjct: 194 EGLSNLRYLNL---AMCNLREIPN-LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLW 249
Query: 277 LQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNL 336
+ + I I N ++ L ++L++NNLT LP LF L +L ++ L +NPW C C++
Sbjct: 250 MIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDI 309
Query: 337 MWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFE----------TGPQGG 386
+WL W+K A C P ++G I ++ C+ +G
Sbjct: 310 LWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGM 369
Query: 387 VANAAAK-TTASNHASATTPQGSLFTLKAKRPGLR-LPDSNIDYPMAT 432
A + +T+ S TP G++ T A + + L D +++ T
Sbjct: 370 AAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVT 417
>gi|198041768 synleurin [Homo sapiens]
Length = 622
Score = 130 bits (327), Expect = 4e-30
Identities = 118/393 (30%), Positives = 171/393 (43%), Gaps = 71/393 (18%)
Query: 38 CYGLIAFLTEVIDSTTCPSVCR-CDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQI--- 93
CY L+ E++ C SVC+ C I C + GL+SIP + P+ LYL N I
Sbjct: 19 CYLLLLLHKEILG---CSSVCQLCTGRQINCRNLGLSSIPKNFPESTVFLYLTGNNISYI 75
Query: 94 ----------------NNAGI----------------------------PQDLKTKVNVQ 109
+N+ I P K +N++
Sbjct: 76 NESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLR 135
Query: 110 VIYLYENDLDEFP---INLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTV 166
+YL N + P N S++ L+LQ N + + + + L L L +N++ +
Sbjct: 136 NLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNI--L 193
Query: 167 SIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELR---LDDNRISTIPLHAFKGLNS 223
I E F + L L+L N+L+ +PS L+ LR L N I I AFKGL +
Sbjct: 194 RISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLAN 253
Query: 224 LRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQK----LYLQD 279
L L+L + + N + D FS + NL L L N L LN + L K L L
Sbjct: 254 LEYLLLKNSRIRN--VTRDGFSGINNLKHLILSHNDL--ENLNSDTFSLLKNLIYLKLDR 309
Query: 280 NAISHIPYNTLAKM-RELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMW 338
N I I +T M L+ L+LS NNLT L + L +L L +NPW C C L+
Sbjct: 310 NRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECNCKLLG 369
Query: 339 LRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDI 371
LRDW+ + A +N+ CQ P +RG A++ I
Sbjct: 370 LRDWLASSAITLNI---YCQNPPSMRGRALRYI 399
>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
sapiens]
Length = 587
Score = 126 bits (317), Expect = 6e-29
Identities = 99/306 (32%), Positives = 151/306 (49%), Gaps = 21/306 (6%)
Query: 79 IPDDA-------TTLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDEFPINLPR---S 128
IPD A T L L N + + P+ + N+QV+ LYEN L + P+ +
Sbjct: 170 IPDGAFDHLVGLTKLNLGKNSLTHIS-PRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVN 228
Query: 129 LRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNH 188
L+EL LQ N + ++ L++L+L +N +S + F QL L L N
Sbjct: 229 LQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHIS--QLPPSIFMQLPQLNRLTLFGNS 286
Query: 189 LSSIPSGL---PHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFS 245
L + G+ L EL L DN IS++P + F L L+ L+L N ++ I+ F+
Sbjct: 287 LKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISF--ISPGAFN 344
Query: 246 RLQNLTELSLVRNSLAAPPLNL--PSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSN 303
L L ELSL N+L N+ A+LQ + LQ+N + +P N A + L + L N
Sbjct: 345 GLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQN 404
Query: 304 NNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGL-MCQGPEK 362
N L LP G+FD LG L +L L +NPW C +++ LR+W+ + + +C P
Sbjct: 405 NQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPAN 464
Query: 363 VRGMAI 368
VRG ++
Sbjct: 465 VRGQSL 470
Score = 102 bits (253), Expect = 2e-21
Identities = 88/284 (30%), Positives = 134/284 (47%), Gaps = 14/284 (4%)
Query: 54 CPSVCRCDNGF-IYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIY 112
CPS C C + C + ++P +P +A +L + N I L + +
Sbjct: 31 CPSECTCSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALI-ALR 89
Query: 113 LYENDLDEFPINLPR---SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIE 169
+ +N+L R SLR L L +N ++ + + LE L L N + + I+
Sbjct: 90 IEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQL--LQIQ 147
Query: 170 EDAFADSKQLKLLFLSRNHLSSIPSG-LPHT--LEELRLDDNRISTIPLHAFKGLNSLRR 226
F+ LK L L NHL IP G H L +L L N ++ I F+ L +L+
Sbjct: 148 PAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQV 207
Query: 227 LVLDGNLLANQRIADDTFSRLQNLTELSLVRN--SLAAPPLNLPSAHLQKLYLQDNAISH 284
L L N L + I TF L NL EL+L +N L +P L + +LQ+LYL +N IS
Sbjct: 208 LRLYENRLTD--IPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQ 265
Query: 285 IPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
+P + ++ +L RL L N+L L G+F + NL +L L +N
Sbjct: 266 LPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDN 309
>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
sapiens]
Length = 581
Score = 126 bits (317), Expect = 6e-29
Identities = 99/306 (32%), Positives = 151/306 (49%), Gaps = 21/306 (6%)
Query: 79 IPDDA-------TTLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDEFPINLPR---S 128
IPD A T L L N + + P+ + N+QV+ LYEN L + P+ +
Sbjct: 164 IPDGAFDHLVGLTKLNLGKNSLTHIS-PRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVN 222
Query: 129 LRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNH 188
L+EL LQ N + ++ L++L+L +N +S + F QL L L N
Sbjct: 223 LQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHIS--QLPPSIFMQLPQLNRLTLFGNS 280
Query: 189 LSSIPSGL---PHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFS 245
L + G+ L EL L DN IS++P + F L L+ L+L N ++ I+ F+
Sbjct: 281 LKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISF--ISPGAFN 338
Query: 246 RLQNLTELSLVRNSLAAPPLNL--PSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSN 303
L L ELSL N+L N+ A+LQ + LQ+N + +P N A + L + L N
Sbjct: 339 GLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQN 398
Query: 304 NNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGL-MCQGPEK 362
N L LP G+FD LG L +L L +NPW C +++ LR+W+ + + +C P
Sbjct: 399 NQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPAN 458
Query: 363 VRGMAI 368
VRG ++
Sbjct: 459 VRGQSL 464
Score = 102 bits (253), Expect = 2e-21
Identities = 88/284 (30%), Positives = 134/284 (47%), Gaps = 14/284 (4%)
Query: 54 CPSVCRCDNGF-IYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIY 112
CPS C C + C + ++P +P +A +L + N I L + +
Sbjct: 25 CPSECTCSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALI-ALR 83
Query: 113 LYENDLDEFPINLPR---SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIE 169
+ +N+L R SLR L L +N ++ + + LE L L N + + I+
Sbjct: 84 IEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQL--LQIQ 141
Query: 170 EDAFADSKQLKLLFLSRNHLSSIPSG-LPHT--LEELRLDDNRISTIPLHAFKGLNSLRR 226
F+ LK L L NHL IP G H L +L L N ++ I F+ L +L+
Sbjct: 142 PAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQV 201
Query: 227 LVLDGNLLANQRIADDTFSRLQNLTELSLVRN--SLAAPPLNLPSAHLQKLYLQDNAISH 284
L L N L + I TF L NL EL+L +N L +P L + +LQ+LYL +N IS
Sbjct: 202 LRLYENRLTD--IPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQ 259
Query: 285 IPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
+P + ++ +L RL L N+L L G+F + NL +L L +N
Sbjct: 260 LPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDN 303
>gi|45505137 podocan [Homo sapiens]
Length = 661
Score = 126 bits (316), Expect = 7e-29
Identities = 85/282 (30%), Positives = 135/282 (47%), Gaps = 27/282 (9%)
Query: 51 STTCPSVCRCDN-GFIYCNDRGLTSIPADIPDDAT------------------------T 85
+ +CP C C G + C L P D+P+ T
Sbjct: 113 AVSCPRDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRLET 172
Query: 86 LYLQNNQINNAGIPQD-LKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIAR 144
L LQNN++ + G+P+ + N+ +YL N L P LP +L + N + I
Sbjct: 173 LNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYG 232
Query: 145 DSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELR 204
+ + P L ++L +N ++ + ++ F S +++L LS N L +P LP L +L
Sbjct: 233 LTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLH 292
Query: 205 LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPP 264
L +N++ IP AF L+SLR L L N L ++ + ++TF +L +L L L N+L+ P
Sbjct: 293 LKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVP 352
Query: 265 LNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNL 306
LP + L L+L+ NAI + N L +R LE L L +N L
Sbjct: 353 AGLPRS-LVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQL 393
Score = 114 bits (286), Expect = 2e-25
Identities = 79/255 (30%), Positives = 127/255 (49%), Gaps = 26/255 (10%)
Query: 85 TLYLQNNQINNAGIPQDL-KTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIA 143
++YL NN++ +AG+P ++ NV+V+ L N L P +LP +L +LHL++N + I
Sbjct: 243 SVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIP 302
Query: 144 RDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEEL 203
+ + + L +L+L +N ++ ++ + F L+ L LS N+LS +P+GLP +L L
Sbjct: 303 PGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLL 362
Query: 204 RLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAP 263
L+ N I ++ + + SL L+L N L Q I F L+ L + L N+L
Sbjct: 363 HLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERV 422
Query: 264 PLNLP-----------------------SAHLQKLYLQDNAIS--HIPYNTLAKMRELER 298
P LP + L++L L N I+ + + K+R L
Sbjct: 423 PSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRS 482
Query: 299 LDLSNNNLTTLPRGL 313
LDLS N L TLP GL
Sbjct: 483 LDLSGNRLHTLPPGL 497
Score = 112 bits (280), Expect = 1e-24
Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 2/222 (0%)
Query: 86 LYLQNNQINNAGI-PQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIAR 144
L L +NQ+ GI P + + ++LY N L+ P LPR +R L + N + I R
Sbjct: 386 LLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGR 445
Query: 145 DSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELR 204
+ A LE+L+L N +++ + DAF + L+ L LS N L ++P GLP + L+
Sbjct: 446 EDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLK 505
Query: 205 LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPP 264
+ N ++ + A G+ LR L L N L ++ + + L +L L + N L P
Sbjct: 506 VKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIP 565
Query: 265 LNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNL 306
LP + L+ LYLQ+N IS +P N L+ + L N L
Sbjct: 566 EGLPES-LEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKL 606
Score = 103 bits (258), Expect = 4e-22
Identities = 83/269 (30%), Positives = 123/269 (45%), Gaps = 29/269 (10%)
Query: 86 LYLQNNQINNAGIPQDLKTKVN-VQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIAR 144
LYLQNN + + G+ + K++ ++ + L N+L P LPRSL LHL+ N +R++
Sbjct: 315 LYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDA 374
Query: 145 DSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELR 204
+ L I LE L L N + I AF K+L + L N L +PSGLP + L
Sbjct: 375 NVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLM 434
Query: 205 LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPP 264
+ N+I+ I F L L L N + + ++ D F +L+ L L L N L P
Sbjct: 435 ILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLP 494
Query: 265 LNLP-----------------------SAHLQKLYLQDNAISHIPYNTLA--KMRELERL 299
LP A L++LYL N + A + L+ L
Sbjct: 495 PGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLL 554
Query: 300 DLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
D++ N LT +P GL + +L L L+NN
Sbjct: 555 DIAGNQLTEIPEGLPE---SLEYLYLQNN 580
Score = 91.7 bits (226), Expect = 2e-18
Identities = 66/212 (31%), Positives = 99/212 (46%), Gaps = 25/212 (11%)
Query: 117 DLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADS 176
DL EFP +LP L LQ+N + I + L+R+ LE L+L +N +++ + E AF
Sbjct: 134 DLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHL 193
Query: 177 KQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLAN 236
L L+L+ N L+ P LP+ L + N ++ I F +LR + L N LA+
Sbjct: 194 TNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLAD 253
Query: 237 QRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMREL 296
+ D+ F+ N+ L L N L P +LP A L
Sbjct: 254 AGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA-------------------------L 288
Query: 297 ERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
+L L NN L +P G F +L +L +L L+NN
Sbjct: 289 YKLHLKNNKLEKIPPGAFSELSSLRELYLQNN 320
Score = 91.3 bits (225), Expect = 3e-18
Identities = 59/184 (32%), Positives = 100/184 (54%), Gaps = 6/184 (3%)
Query: 81 DDATTLYLQN-----NQINNAGIPQDLKTKVNV-QVIYLYENDLDEFPINLPRSLRELHL 134
D ATT +L+ N+I + + +D K+ + + + L N L P LPR++ L +
Sbjct: 447 DFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKV 506
Query: 135 QDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPS 194
+ N + +AR +L + L +L+L N + + ++ A+ D L+LL ++ N L+ IP
Sbjct: 507 KRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE 566
Query: 195 GLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELS 254
GLP +LE L L +N+IS +P +AF +L+ + L N LA + D F RL++L L
Sbjct: 567 GLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLD 626
Query: 255 LVRN 258
+ N
Sbjct: 627 IEGN 630
Score = 29.6 bits (65), Expect = 9.5
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 3/48 (6%)
Query: 72 LTSIPADIPDDATTLYLQNNQINNAGIPQD-LKTKVNVQVIYLYENDL 118
LT IP +P+ LYLQNN+I + +P + + N++ I+L N L
Sbjct: 561 LTEIPEGLPESLEYLYLQNNKI--SAVPANAFDSTPNLKGIFLRFNKL 606
>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
Length = 713
Score = 125 bits (313), Expect = 2e-28
Identities = 113/380 (29%), Positives = 165/380 (43%), Gaps = 47/380 (12%)
Query: 51 STTCPSVCRCDN--GFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNV 108
+T+CP C C N + C R L +PA IP + L LQ N I Q ++T
Sbjct: 54 ATSCPVACSCSNQASRVICTRRDLAEVPASIPVNTRYLNLQENGI------QVIRTDTFK 107
Query: 109 QVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSI 168
+ R L L L N VR I + +P L L L DN ++TV
Sbjct: 108 HL----------------RHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPT 151
Query: 169 EEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDD----NRISTIPLHAFKGLNSL 224
+ AF +L+ L+L N + SIPS + + LR D R+ I AF+GL +L
Sbjct: 152 Q--AFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNL 209
Query: 225 RRLVLDGNLLANQRIADD--TFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAI 282
R L L + N + + RL+ L ELS R L P L+KL+L +
Sbjct: 210 RYLNLG---MCNLKDIPNLTALVRLEEL-ELSGNRLDLIRPGSFQGLTSLRKLWLMHAQV 265
Query: 283 SHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDW 342
+ I N ++ LE L+LS+NNL +LP LF L L ++ L +NPW C C+++WL W
Sbjct: 266 ATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWW 325
Query: 343 VKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFE----------TGPQGGVANAAA 392
+K C P ++G I ++ C+ +G A
Sbjct: 326 LKETVPSNTTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKC 385
Query: 393 KT-TASNHASATTPQGSLFT 411
+T T+ + TP G+L T
Sbjct: 386 RTGTSMTSVNWLTPNGTLMT 405
>gi|15029530 leucine rich repeat containing 4 [Homo sapiens]
Length = 653
Score = 122 bits (306), Expect = 1e-27
Identities = 122/470 (25%), Positives = 190/470 (40%), Gaps = 107/470 (22%)
Query: 1 MVVAHPTATATTTPTATVTATVVMTTATMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRC 60
+ V H T A P +TA V W+ LC + A + CPSVC C
Sbjct: 7 VTVHHHTWNAILLPFVYLTAQV-----------WI-LCAAIAAAASA--GPQNCPSVCSC 52
Query: 61 DNGF--IYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDL 118
N F + C RGL+
Sbjct: 53 SNQFSKVVCTRRGLS--------------------------------------------- 67
Query: 119 DEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQ 178
E P +P + R L+L +NN++ I D+ + LE L L NS+ IE AF
Sbjct: 68 -EVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIR--QIEVGAFNGLAS 124
Query: 179 LKLLFLSRNHLSSIPSGLPHTLEELR---LDDNRISTIPLHAFKGLNSLRRLVLDGNLLA 235
L L L N L+ IPSG L +LR L +N I +IP +AF + SL RL L G L
Sbjct: 125 LNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDL-GELKK 183
Query: 236 NQRIADDTFSRLQNLTELSLVRNSLAAPP----------LNLPSAH-------------- 271
+ I++ F L NL L+L ++ P L + H
Sbjct: 184 LEYISEGAFEGLFNLKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSS 243
Query: 272 LQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWF 331
L+KL++ ++ +S I N + L L+L++NNL++LP LF L L +L L +NPW
Sbjct: 244 LKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWN 303
Query: 332 CGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFETGP-------- 383
C C+++WL W++ + C P +RG + ++ +C + P
Sbjct: 304 CDCDILWLAWWLREYIPTNSTCCGRCHAPMHMRGRYLVEVDQASFQC--SAPFIMDAPRD 361
Query: 384 ----QGGVANAAAKTTASNHASATTPQGSLFTLKAKRPGLR-LPDSNIDY 428
+G +A +T + P G++ + ++ P + L D +++
Sbjct: 362 LNISEGRMAELKCRTPPMSSVKWLLPNGTVLSHASRHPRISVLNDGTLNF 411
>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 121 bits (303), Expect = 2e-27
Identities = 78/254 (30%), Positives = 128/254 (50%), Gaps = 26/254 (10%)
Query: 54 CPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNA--GIPQDLKTK------ 105
CP C+C + C+D GL +P D+P D T L LQNN+I G ++LK
Sbjct: 54 CPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILV 113
Query: 106 ---------------VNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARI 150
V ++ +YL +N L E P +P++L+EL +N + + + + +
Sbjct: 114 NNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGL 173
Query: 151 PLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRI 210
+ + L N + + IE AF K+L + ++ +++SIP GLP +L EL LD N+I
Sbjct: 174 NQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKI 233
Query: 211 STIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPS- 269
S + + KGLN+L +L L N ++ + + + + +L EL L N L P L
Sbjct: 234 SRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH 291
Query: 270 AHLQKLYLQDNAIS 283
++Q +YL +N IS
Sbjct: 292 KYIQVVYLHNNNIS 305
Score = 66.2 bits (160), Expect = 9e-11
Identities = 55/218 (25%), Positives = 93/218 (42%), Gaps = 48/218 (22%)
Query: 103 KTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNS 162
+ + +++V+ + LD+ P +LP L LQ+N + I + L L L +N
Sbjct: 57 RCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNK 116
Query: 163 VSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLN 222
+S VS AF +L+ L+LS+N L +P +P TL+ELR +N I+ + F GLN
Sbjct: 117 ISKVS--PGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLN 174
Query: 223 SLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAI 282
+ + L N L + I + F Q + +LS +R
Sbjct: 175 QMIVIELGTNPLKSSGIENGAF---QGMKKLSYIR------------------------- 206
Query: 283 SHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNL 320
+++ N+T++P+GL L L
Sbjct: 207 ------------------IADTNITSIPQGLPPSLTEL 226
Score = 30.4 bits (67), Expect = 5.6
Identities = 18/54 (33%), Positives = 26/54 (48%)
Query: 275 LYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
L LQ+N I+ I ++ L L L NN ++ + G F L L +L L N
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKN 139
>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 121 bits (303), Expect = 2e-27
Identities = 78/254 (30%), Positives = 128/254 (50%), Gaps = 26/254 (10%)
Query: 54 CPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNA--GIPQDLKTK------ 105
CP C+C + C+D GL +P D+P D T L LQNN+I G ++LK
Sbjct: 54 CPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILV 113
Query: 106 ---------------VNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARI 150
V ++ +YL +N L E P +P++L+EL +N + + + + +
Sbjct: 114 NNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGL 173
Query: 151 PLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRI 210
+ + L N + + IE AF K+L + ++ +++SIP GLP +L EL LD N+I
Sbjct: 174 NQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKI 233
Query: 211 STIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPS- 269
S + + KGLN+L +L L N ++ + + + + +L EL L N L P L
Sbjct: 234 SRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH 291
Query: 270 AHLQKLYLQDNAIS 283
++Q +YL +N IS
Sbjct: 292 KYIQVVYLHNNNIS 305
Score = 66.2 bits (160), Expect = 9e-11
Identities = 55/218 (25%), Positives = 93/218 (42%), Gaps = 48/218 (22%)
Query: 103 KTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNS 162
+ + +++V+ + LD+ P +LP L LQ+N + I + L L L +N
Sbjct: 57 RCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNK 116
Query: 163 VSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLN 222
+S VS AF +L+ L+LS+N L +P +P TL+ELR +N I+ + F GLN
Sbjct: 117 ISKVS--PGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLN 174
Query: 223 SLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAI 282
+ + L N L + I + F Q + +LS +R
Sbjct: 175 QMIVIELGTNPLKSSGIENGAF---QGMKKLSYIR------------------------- 206
Query: 283 SHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNL 320
+++ N+T++P+GL L L
Sbjct: 207 ------------------IADTNITSIPQGLPPSLTEL 226
Score = 30.4 bits (67), Expect = 5.6
Identities = 18/54 (33%), Positives = 26/54 (48%)
Query: 275 LYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
L LQ+N I+ I ++ L L L NN ++ + G F L L +L L N
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKN 139
>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
Length = 510
Score = 120 bits (302), Expect = 3e-27
Identities = 84/256 (32%), Positives = 123/256 (48%), Gaps = 28/256 (10%)
Query: 85 TLYLQNNQINNAGIPQD-LKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIA 143
++YL NNQ++NAG+P D + + + L N L P +LP SL LHLQ+N + +
Sbjct: 171 SVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVP 230
Query: 144 RDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEEL 203
R +L+R L +L+L N ++ ++ F+ L+ L LS N L+++P+GLP TL L
Sbjct: 231 RGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAIL 290
Query: 204 RLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAP 263
L NRI + G LR L+L N L + + L+ L L L N L
Sbjct: 291 HLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRV 350
Query: 264 PLNLPSAHLQKLYLQDNAIS----------------HIPYNTLA----------KMRELE 297
P LP L+ L L N ++ ++ YN LA ++R L
Sbjct: 351 PPALP-RRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALR 409
Query: 298 RLDLSNNNLTTLPRGL 313
LDL+ N LT LP GL
Sbjct: 410 SLDLAGNQLTRLPMGL 425
Score = 115 bits (287), Expect = 2e-25
Identities = 87/247 (35%), Positives = 116/247 (46%), Gaps = 4/247 (1%)
Query: 85 TLYLQNNQINNAGIPQD-LKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIA 143
TL L NN I++ G+P + ++ +Q + + N L P LPRSLR L N V I
Sbjct: 100 TLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIF 159
Query: 144 RDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEEL 203
+ P L ++L +N +S + DAF S+ + L LS N LS +P LP +LE L
Sbjct: 160 PLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERL 219
Query: 204 RLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAP 263
L +N IS +P A LR L L N L + + TFS+L +L L L N L
Sbjct: 220 HLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTV 279
Query: 264 PLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNL--TTLPRGLFDDLGNLA 321
P LP L L+L N I + L R L L L +N L + LP G L L
Sbjct: 280 PAGLPRT-LAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLH 338
Query: 322 QLLLRNN 328
L L N
Sbjct: 339 TLHLYGN 345
Score = 104 bits (260), Expect = 2e-22
Identities = 72/223 (32%), Positives = 113/223 (50%), Gaps = 27/223 (12%)
Query: 117 DLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADS 176
DL FP N+ R+ + L LQ+N ++ + + L+R+ L L+L +N +S+ + ++AF
Sbjct: 62 DLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESL 121
Query: 177 KQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLAN 236
QL+ L ++ N LS P LP +L L N++ I F +LR + L N L+N
Sbjct: 122 TQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSN 181
Query: 237 QRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIP---------- 286
+ D F + + LSL N L+ P +LP + L++L+LQ+N IS +P
Sbjct: 182 AGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPS-LERLHLQNNLISKVPRGALSRQTQL 240
Query: 287 ----------------YNTLAKMRELERLDLSNNNLTTLPRGL 313
T +K+ LE LDLS+N LTT+P GL
Sbjct: 241 RELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL 283
Score = 94.7 bits (234), Expect = 2e-19
Identities = 69/222 (31%), Positives = 103/222 (46%), Gaps = 2/222 (0%)
Query: 86 LYLQNNQINNAGIPQDLKTKVN-VQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIAR 144
LYLQ+NQ+ ++G+ +K++ ++ + L N L P LPR+L LHL N +R +
Sbjct: 243 LYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEA 302
Query: 145 DSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELR 204
L L L L N + + + A + L L L N L +P LP L L
Sbjct: 303 ARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALV 362
Query: 205 LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPP 264
L N ++ + L L L N LA+ R+ F RL+ L L L N L P
Sbjct: 363 LPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLP 422
Query: 265 LNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNL 306
+ LP+ L+ L LQ N + + LA + +L L L++N L
Sbjct: 423 MGLPTG-LRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRL 463
Score = 86.7 bits (213), Expect = 7e-17
Identities = 57/166 (34%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
Query: 86 LYLQNNQINNAGIPQD-LKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIAR 144
L LQ+NQ+ ++G+P L+ + ++LY N LD P LPR LR L L N+V +
Sbjct: 314 LLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA 373
Query: 145 DSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELR 204
L P L +L+L N +++ + AF + L+ L L+ N L+ +P GLP L L+
Sbjct: 374 RDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ 433
Query: 205 LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNL 250
L N++ + GL+ LR L L N L I T+ LQ L
Sbjct: 434 LQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQAL 479
>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
Length = 512
Score = 120 bits (302), Expect = 3e-27
Identities = 84/256 (32%), Positives = 123/256 (48%), Gaps = 28/256 (10%)
Query: 85 TLYLQNNQINNAGIPQD-LKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIA 143
++YL NNQ++NAG+P D + + + L N L P +LP SL LHLQ+N + +
Sbjct: 173 SVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVP 232
Query: 144 RDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEEL 203
R +L+R L +L+L N ++ ++ F+ L+ L LS N L+++P+GLP TL L
Sbjct: 233 RGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAIL 292
Query: 204 RLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAP 263
L NRI + G LR L+L N L + + L+ L L L N L
Sbjct: 293 HLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRV 352
Query: 264 PLNLPSAHLQKLYLQDNAIS----------------HIPYNTLA----------KMRELE 297
P LP L+ L L N ++ ++ YN LA ++R L
Sbjct: 353 PPALP-RRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALR 411
Query: 298 RLDLSNNNLTTLPRGL 313
LDL+ N LT LP GL
Sbjct: 412 SLDLAGNQLTRLPMGL 427
Score = 115 bits (287), Expect = 2e-25
Identities = 87/247 (35%), Positives = 116/247 (46%), Gaps = 4/247 (1%)
Query: 85 TLYLQNNQINNAGIPQD-LKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIA 143
TL L NN I++ G+P + ++ +Q + + N L P LPRSLR L N V I
Sbjct: 102 TLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIF 161
Query: 144 RDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEEL 203
+ P L ++L +N +S + DAF S+ + L LS N LS +P LP +LE L
Sbjct: 162 PLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERL 221
Query: 204 RLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAP 263
L +N IS +P A LR L L N L + + TFS+L +L L L N L
Sbjct: 222 HLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTV 281
Query: 264 PLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNL--TTLPRGLFDDLGNLA 321
P LP L L+L N I + L R L L L +N L + LP G L L
Sbjct: 282 PAGLPRT-LAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLH 340
Query: 322 QLLLRNN 328
L L N
Sbjct: 341 TLHLYGN 347
Score = 104 bits (260), Expect = 2e-22
Identities = 72/223 (32%), Positives = 113/223 (50%), Gaps = 27/223 (12%)
Query: 117 DLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADS 176
DL FP N+ R+ + L LQ+N ++ + + L+R+ L L+L +N +S+ + ++AF
Sbjct: 64 DLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESL 123
Query: 177 KQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLAN 236
QL+ L ++ N LS P LP +L L N++ I F +LR + L N L+N
Sbjct: 124 TQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSN 183
Query: 237 QRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIP---------- 286
+ D F + + LSL N L+ P +LP + L++L+LQ+N IS +P
Sbjct: 184 AGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPS-LERLHLQNNLISKVPRGALSRQTQL 242
Query: 287 ----------------YNTLAKMRELERLDLSNNNLTTLPRGL 313
T +K+ LE LDLS+N LTT+P GL
Sbjct: 243 RELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL 285
Score = 94.7 bits (234), Expect = 2e-19
Identities = 69/222 (31%), Positives = 103/222 (46%), Gaps = 2/222 (0%)
Query: 86 LYLQNNQINNAGIPQDLKTKVN-VQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIAR 144
LYLQ+NQ+ ++G+ +K++ ++ + L N L P LPR+L LHL N +R +
Sbjct: 245 LYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEA 304
Query: 145 DSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELR 204
L L L L N + + + A + L L L N L +P LP L L
Sbjct: 305 ARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALV 364
Query: 205 LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPP 264
L N ++ + L L L N LA+ R+ F RL+ L L L N L P
Sbjct: 365 LPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLP 424
Query: 265 LNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNL 306
+ LP+ L+ L LQ N + + LA + +L L L++N L
Sbjct: 425 MGLPTG-LRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRL 465
Score = 86.7 bits (213), Expect = 7e-17
Identities = 57/166 (34%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
Query: 86 LYLQNNQINNAGIPQD-LKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIAR 144
L LQ+NQ+ ++G+P L+ + ++LY N LD P LPR LR L L N+V +
Sbjct: 316 LLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA 375
Query: 145 DSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELR 204
L P L +L+L N +++ + AF + L+ L L+ N L+ +P GLP L L+
Sbjct: 376 RDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ 435
Query: 205 LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNL 250
L N++ + GL+ LR L L N L I T+ LQ L
Sbjct: 436 LQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQAL 481
>gi|71040111 fibromodulin precursor [Homo sapiens]
Length = 376
Score = 119 bits (299), Expect = 7e-27
Identities = 94/292 (32%), Positives = 135/292 (46%), Gaps = 43/292 (14%)
Query: 50 DSTTCPSVCRCDNGF---IYCNDRGLTSIPADIPDDATTLYLQNNQI---------NNAG 97
D CP C C F +YC++R L +P +P +Y QNNQI N G
Sbjct: 72 DPRDCPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDNATG 130
Query: 98 I-------PQDLKTKVNVQV---------IYLYENDLDEFPINLPRSLRELHLQDNNVRT 141
+ Q KV +V +YL N+L P LPRSLRELHL N +
Sbjct: 131 LLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISR 190
Query: 142 IARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLE 201
+ ++L + L L+L N + V + + L LL LS NHL +P GLP LE
Sbjct: 191 VPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPSALE 247
Query: 202 ELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSL- 260
+L ++ N + T+P F+G L + L N L N +A +TF+ +L EL L N L
Sbjct: 248 QLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNS-SSLLELDLSYNQLQ 306
Query: 261 AAPPLNLPSAHLQKLYLQDNAISHIPYNT------LAKMRELERLDLSNNNL 306
PP+N +L+ LYLQ N I+ ++ + +L+ L L N +
Sbjct: 307 KIPPVN---TNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEI 355
Score = 84.7 bits (208), Expect = 2e-16
Identities = 62/214 (28%), Positives = 107/214 (50%), Gaps = 7/214 (3%)
Query: 111 IYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEE 170
+Y +L P +P ++ ++ Q+N + +I L + L N +++ +
Sbjct: 90 MYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGR 148
Query: 171 DAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLD 230
F+ + L+ L+L N+L+ +P LP +L EL LD N+IS +P +A +GL +L L L
Sbjct: 149 KVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQ 208
Query: 231 GNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTL 290
N + + L++L L L N L P LPSA L++LY++ N + +P +
Sbjct: 209 HNEIQE---VGSSMRGLRSLILLDLSYNHLRKVPDGLPSA-LEQLYMEHNNVYTVPDSYF 264
Query: 291 AKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLL 324
+L + LS+N+LT GL + N + LL
Sbjct: 265 RGAPKLLYVRLSHNSLTN--NGLASNTFNSSSLL 296
>gi|4502403 biglycan preproprotein [Homo sapiens]
Length = 368
Score = 118 bits (295), Expect = 2e-26
Identities = 88/268 (32%), Positives = 122/268 (45%), Gaps = 29/268 (10%)
Query: 51 STTCPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLK------- 103
S CP C C + C+D GL S+P +I D T L LQNN I+ D K
Sbjct: 60 SAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELR-KDDFKGLQHLYA 118
Query: 104 --------TKVN---------VQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDS 146
+K++ +Q +Y+ +N L E P NLP SL EL + DN +R + +
Sbjct: 119 LVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGV 178
Query: 147 LARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLD 206
+ + + + + N + E AF D +L L +S L+ IP LP TL EL LD
Sbjct: 179 FSGLRNMNCIEMGGNPLENSGFEPGAF-DGLKLNYLRISEAKLTGIPKDLPETLNELHLD 237
Query: 207 DNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLN 266
N+I I L + L RL L N + + I + + S L L EL L N LA P
Sbjct: 238 HNKIQAIELEDLLRYSKLYRLGLGHNQI--RMIENGSLSFLPTLRELHLDNNKLARVPSG 295
Query: 267 LPSAH-LQKLYLQDNAISHIPYNTLAKM 293
LP LQ +YL N I+ + N M
Sbjct: 296 LPDLKLLQVVYLHSNNITKVGVNDFCPM 323
Score = 61.6 bits (148), Expect = 2e-09
Identities = 50/162 (30%), Positives = 78/162 (48%), Gaps = 5/162 (3%)
Query: 158 LDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHA 217
LD +SV+ F L+++ S L S+P + L L +N IS +
Sbjct: 50 LDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDD 109
Query: 218 FKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYL 277
FKGL L LVL N ++ +I + FS L+ L +L + +N L P NLPS+ L +L +
Sbjct: 110 FKGLQHLYALVLVNNKIS--KIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSS-LVELRI 166
Query: 278 QDNAISHIPYNTLAKMRELERLDLSNNNL--TTLPRGLFDDL 317
DN I +P + +R + +++ N L + G FD L
Sbjct: 167 HDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL 208
>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
Length = 545
Score = 116 bits (291), Expect = 6e-26
Identities = 114/429 (26%), Positives = 175/429 (40%), Gaps = 109/429 (25%)
Query: 54 CPSVCRCDNGFIYCNDRGLTSIPADIPD------------------------DATTLYLQ 89
CP C C ++C+D L ++P DIP + T +
Sbjct: 22 CPMGCDCFVQEVFCSDEELATVPLDIPPYTKNIIFVETSFTTLETRAFGSNPNLTKVVFL 81
Query: 90 NNQINN------AGIPQ------------DLKTKV-----NVQVIYLYENDLDEFPINLP 126
N Q+ G+P+ +L T + ++ + L N L+ P L
Sbjct: 82 NTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLF 141
Query: 127 R---SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLF 183
+ +L LHLQ N ++ + R + L+ L+L N ++ + E+ F L+ L
Sbjct: 142 QHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLA--QLPEELFHPLTSLQTLK 199
Query: 184 LSRNHLSSIPSGL---PHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIA 240
LS N LS +P G+ +L+EL LD N IS +P F L L RL L N + + ++
Sbjct: 200 LSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLS 259
Query: 241 DDTFSRLQNLTELSLVRNSLAAPPLNLPS--------------------------AHLQK 274
F+ L NLT LSL N L P L + ++L+
Sbjct: 260 --IFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRS 317
Query: 275 LYLQDNAISHIPYNTLAKMREL------------------------ERLDLSNNNLTTLP 310
L L NAI+H+P + EL E L LS N LTTLP
Sbjct: 318 LMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLP 377
Query: 311 RGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARA-AVVNVRGLMCQGPEKVRGMAIK 369
G+FD NL L L NPW C C+L +L +W++ ++N++ C GP ++G +
Sbjct: 378 EGIFDTNYNLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNIQ-TYCAGPAYLKGQVVP 436
Query: 370 DITSEMDEC 378
+ + C
Sbjct: 437 ALNEKQLVC 445
>gi|156139147 leucine rich repeat transmembrane neuronal 4 isoform b
[Homo sapiens]
Length = 518
Score = 113 bits (283), Expect = 5e-25
Identities = 114/447 (25%), Positives = 184/447 (41%), Gaps = 57/447 (12%)
Query: 54 CPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQ--DLKTKVNVQVI 111
CP CRCD +YC IP +I + L L+ N I Q L + + +
Sbjct: 34 CPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLD 93
Query: 112 YLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEED 171
+ Y + +DE R L+EL L N + + + +P L L L N + T+ E+
Sbjct: 94 HNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQ- 152
Query: 172 AFADSKQLKLLFLSRNHLSSIPSGL---PHTLEELRLDDNRISTIPLHAFKGLNSLRRLV 228
F ++L +L L N L ++P + L+ L L NR+ ++ +AF GL L+ L
Sbjct: 153 -FKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELH 211
Query: 229 LDGNLLANQRIADDTFSRLQNLTELSLVRNSL--AAPPLNLPSAHLQKLYLQDNAISHIP 286
L+ N + A F RL NL + L N + + L + L L L N I I
Sbjct: 212 LEHNQFSKINFAH--FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIE 269
Query: 287 YNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKAR 346
T + L++L+L +N LT + + + +L + L N W C ++ L W+K
Sbjct: 270 PGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLK-- 327
Query: 347 AAVVNVRG-----LMCQGPEKVRGMAIKDITSEMDECFETGPQGGVANAAAKTTASNHAS 401
N +G ++C GP+ ++G + D + C E T +H
Sbjct: 328 ----NFKGNKESTMICAGPKHIQGEKVSDAVETYNICSE---------VQVVNTERSHLV 374
Query: 402 ATTPQ----------------GSLFTLKAKRPGLRLPDSNIDY------PMATGDGAKTL 439
TPQ S F + PG ++P + +Y + G A L
Sbjct: 375 PQTPQKPLIIPRPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHVSFHKIIAGSVALFL 434
Query: 440 AIHVKALTADSIRITWKATLPASSFRL 466
++ + L I ++WK PAS +L
Sbjct: 435 SVAMILLV---IYVSWK-RYPASMKQL 457
>gi|197927168 leucine rich repeat transmembrane neuronal 4 isoform a
[Homo sapiens]
Length = 590
Score = 113 bits (283), Expect = 5e-25
Identities = 114/447 (25%), Positives = 184/447 (41%), Gaps = 57/447 (12%)
Query: 54 CPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQ--DLKTKVNVQVI 111
CP CRCD +YC IP +I + L L+ N I Q L + + +
Sbjct: 34 CPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLD 93
Query: 112 YLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEED 171
+ Y + +DE R L+EL L N + + + +P L L L N + T+ E+
Sbjct: 94 HNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQ- 152
Query: 172 AFADSKQLKLLFLSRNHLSSIPSGL---PHTLEELRLDDNRISTIPLHAFKGLNSLRRLV 228
F ++L +L L N L ++P + L+ L L NR+ ++ +AF GL L+ L
Sbjct: 153 -FKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELH 211
Query: 229 LDGNLLANQRIADDTFSRLQNLTELSLVRNSL--AAPPLNLPSAHLQKLYLQDNAISHIP 286
L+ N + A F RL NL + L N + + L + L L L N I I
Sbjct: 212 LEHNQFSKINFAH--FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIE 269
Query: 287 YNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKAR 346
T + L++L+L +N LT + + + +L + L N W C ++ L W+K
Sbjct: 270 PGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLK-- 327
Query: 347 AAVVNVRG-----LMCQGPEKVRGMAIKDITSEMDECFETGPQGGVANAAAKTTASNHAS 401
N +G ++C GP+ ++G + D + C E T +H
Sbjct: 328 ----NFKGNKESTMICAGPKHIQGEKVSDAVETYNICSE---------VQVVNTERSHLV 374
Query: 402 ATTPQ----------------GSLFTLKAKRPGLRLPDSNIDY------PMATGDGAKTL 439
TPQ S F + PG ++P + +Y + G A L
Sbjct: 375 PQTPQKPLIIPRPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHVSFHKIIAGSVALFL 434
Query: 440 AIHVKALTADSIRITWKATLPASSFRL 466
++ + L I ++WK PAS +L
Sbjct: 435 SVAMILLV---IYVSWK-RYPASMKQL 457
>gi|5901992 keratocan [Homo sapiens]
Length = 352
Score = 112 bits (281), Expect = 9e-25
Identities = 74/220 (33%), Positives = 117/220 (53%), Gaps = 5/220 (2%)
Query: 111 IYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEE 170
+Y L E P +P + L+LQ+N + TI L ++L+ N ++ IE+
Sbjct: 56 LYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEK 114
Query: 171 DAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLD 230
A + K+L LFL N L +PS LP +LE+L+L N++S IP F L +L L L
Sbjct: 115 GALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174
Query: 231 GNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTL 290
N L + DTF L+NL +L++ +N+L P LP A+ +L+L +N+I IP N
Sbjct: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLP-ANTMQLFLDNNSIEGIPENYF 233
Query: 291 AKMRELERLDLSNNNLTT--LPRGLFDDLGNLAQLLLRNN 328
+ ++ L L++N L+ LP F D+ ++ L L +N
Sbjct: 234 NVIPKVAFLRLNHNKLSDEGLPSRGF-DVSSILDLQLSHN 272
Score = 107 bits (266), Expect = 5e-23
Identities = 81/260 (31%), Positives = 124/260 (47%), Gaps = 32/260 (12%)
Query: 54 CPSVCRCDNGF---IYCNDRGLTSIPADIPDDATTLYLQN-------------------- 90
CP C C F +YC +RGL IPA IP LYLQN
Sbjct: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
Query: 91 ----NQINNAGIPQDLKTKV-NVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARD 145
N+I N GI + +++ + ++L +N+L+E P LPRSL +L L N V I +
Sbjct: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
Query: 146 SLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRL 205
+ + + L L L +N + + + D F K L L +++N L ++P LP +L L
Sbjct: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
Query: 206 DDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPL 265
D+N I IP + F + + L L+ N L+++ + F + ++ +L L N L P
Sbjct: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFD-VSSILDLQLSHNQLTKVP- 278
Query: 266 NLPSAHLQKLYLQDNAISHI 285
SAHLQ L+L N I +
Sbjct: 279 -RISAHLQHLHLDHNKIKSV 297
Score = 38.1 bits (87), Expect = 0.027
Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 28/145 (19%)
Query: 72 LTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKV-NVQVIYLYENDLDEFPINLPR--- 127
L ++P +P + L+L NN I GIP++ + V + L N L + LP
Sbjct: 204 LRNMPPRLPANTMQLFLDNNSIE--GIPENYFNVIPKVAFLRLNHNKLSDE--GLPSRGF 259
Query: 128 ---SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSI------------EEDA 172
S+ +L L N + + R S L+ LHLD N + +V++ E D+
Sbjct: 260 DVSSILDLQLSHNQLTKVPRISAH----LQHLHLDHNKIKSVNVSVICPSPSMLPAERDS 315
Query: 173 FADSKQLKLLFLSRNHLS-SIPSGL 196
F+ L+ L L N + IP L
Sbjct: 316 FSYGPHLRYLRLDGNEIKPPIPMAL 340
>gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 110 bits (276), Expect = 3e-24
Identities = 142/600 (23%), Positives = 241/600 (40%), Gaps = 131/600 (21%)
Query: 29 MDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCD-------------NGFIYCNDRGLTSI 75
M LR + L + + V CP +C C+ + CND GL +
Sbjct: 4 MPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTF 63
Query: 76 PADIPDDATTLYLQNNQI-----------NNAGIP---QDLKTKVNVQV--------IYL 113
PA +P + L LQ N I N G+ +L + N+ V +YL
Sbjct: 64 PARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYL 123
Query: 114 YENDLDEFP---INLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVS--- 167
EN L E P ++ +L+EL++ N + TI+ + + L +LHL+ N + ++
Sbjct: 124 EENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKW 183
Query: 168 -------------------IEEDAFADSKQLKLLFLSRNHLSSIPS----GLPHTLEELR 204
I++ F L+ L ++ +L+ IP GL + LE +
Sbjct: 184 FDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLEN-LESIS 242
Query: 205 LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVR------- 257
DNR+ +P A + + +L+ L L+ N + RI FS + +L EL +
Sbjct: 243 FYDNRLIKVPHVALQKVVNLKFLDLNKNPI--NRIRRGDFSNMLHLKELGINNMPELISI 300
Query: 258 NSLAAPPLNLPSAHLQKLYLQDNA-ISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDD 316
+SLA NLP L+K+ +N +S+I N ++ +LE L L++N L+ L G +
Sbjct: 301 DSLAVD--NLPD--LRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIES 356
Query: 317 LGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDI--TSE 374
L NL ++ + +NP C C + W+ + K + L C P + +G ++ +
Sbjct: 357 LPNLKEISIHSNPIRCDCVIRWM-NMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDM 415
Query: 375 MDECF-----ETGPQGGVANAAAKTTASNHASAT----------TPQG------------ 407
M+ C E+ P N A + S H AT TP G
Sbjct: 416 MEICLPLIAPESFPSN--LNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKF 473
Query: 408 --------SLFTLKAKRPGL------RLPDSNIDYPMATGDGA------KTLAIHVKALT 447
+ + K GL L +++ M DG+ +L I ++ +
Sbjct: 474 YVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQ 533
Query: 448 ADSIRITWKATLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICM 507
A+S+ ++WKA+ + W + + + D Y LT L P + Y IC+
Sbjct: 534 ANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICI 593
>gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 110 bits (276), Expect = 3e-24
Identities = 142/600 (23%), Positives = 241/600 (40%), Gaps = 131/600 (21%)
Query: 29 MDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCD-------------NGFIYCNDRGLTSI 75
M LR + L + + V CP +C C+ + CND GL +
Sbjct: 4 MPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTF 63
Query: 76 PADIPDDATTLYLQNNQI-----------NNAGIP---QDLKTKVNVQV--------IYL 113
PA +P + L LQ N I N G+ +L + N+ V +YL
Sbjct: 64 PARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYL 123
Query: 114 YENDLDEFP---INLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVS--- 167
EN L E P ++ +L+EL++ N + TI+ + + L +LHL+ N + ++
Sbjct: 124 EENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKW 183
Query: 168 -------------------IEEDAFADSKQLKLLFLSRNHLSSIPS----GLPHTLEELR 204
I++ F L+ L ++ +L+ IP GL + LE +
Sbjct: 184 FDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLEN-LESIS 242
Query: 205 LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVR------- 257
DNR+ +P A + + +L+ L L+ N + RI FS + +L EL +
Sbjct: 243 FYDNRLIKVPHVALQKVVNLKFLDLNKNPI--NRIRRGDFSNMLHLKELGINNMPELISI 300
Query: 258 NSLAAPPLNLPSAHLQKLYLQDNA-ISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDD 316
+SLA NLP L+K+ +N +S+I N ++ +LE L L++N L+ L G +
Sbjct: 301 DSLAVD--NLPD--LRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIES 356
Query: 317 LGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDI--TSE 374
L NL ++ + +NP C C + W+ + K + L C P + +G ++ +
Sbjct: 357 LPNLKEISIHSNPIRCDCVIRWM-NMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDM 415
Query: 375 MDECF-----ETGPQGGVANAAAKTTASNHASAT----------TPQG------------ 407
M+ C E+ P N A + S H AT TP G
Sbjct: 416 MEICLPLIAPESFPSN--LNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKF 473
Query: 408 --------SLFTLKAKRPGL------RLPDSNIDYPMATGDGA------KTLAIHVKALT 447
+ + K GL L +++ M DG+ +L I ++ +
Sbjct: 474 YVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQ 533
Query: 448 ADSIRITWKATLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICM 507
A+S+ ++WKA+ + W + + + D Y LT L P + Y IC+
Sbjct: 534 ANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICI 593
>gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 110 bits (276), Expect = 3e-24
Identities = 142/600 (23%), Positives = 241/600 (40%), Gaps = 131/600 (21%)
Query: 29 MDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCD-------------NGFIYCNDRGLTSI 75
M LR + L + + V CP +C C+ + CND GL +
Sbjct: 4 MPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTF 63
Query: 76 PADIPDDATTLYLQNNQI-----------NNAGIP---QDLKTKVNVQV--------IYL 113
PA +P + L LQ N I N G+ +L + N+ V +YL
Sbjct: 64 PARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYL 123
Query: 114 YENDLDEFP---INLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVS--- 167
EN L E P ++ +L+EL++ N + TI+ + + L +LHL+ N + ++
Sbjct: 124 EENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKW 183
Query: 168 -------------------IEEDAFADSKQLKLLFLSRNHLSSIPS----GLPHTLEELR 204
I++ F L+ L ++ +L+ IP GL + LE +
Sbjct: 184 FDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLEN-LESIS 242
Query: 205 LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVR------- 257
DNR+ +P A + + +L+ L L+ N + RI FS + +L EL +
Sbjct: 243 FYDNRLIKVPHVALQKVVNLKFLDLNKNPI--NRIRRGDFSNMLHLKELGINNMPELISI 300
Query: 258 NSLAAPPLNLPSAHLQKLYLQDNA-ISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDD 316
+SLA NLP L+K+ +N +S+I N ++ +LE L L++N L+ L G +
Sbjct: 301 DSLAVD--NLPD--LRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIES 356
Query: 317 LGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDI--TSE 374
L NL ++ + +NP C C + W+ + K + L C P + +G ++ +
Sbjct: 357 LPNLKEISIHSNPIRCDCVIRWM-NMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDM 415
Query: 375 MDECF-----ETGPQGGVANAAAKTTASNHASAT----------TPQG------------ 407
M+ C E+ P N A + S H AT TP G
Sbjct: 416 MEICLPLIAPESFPSN--LNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKF 473
Query: 408 --------SLFTLKAKRPGL------RLPDSNIDYPMATGDGA------KTLAIHVKALT 447
+ + K GL L +++ M DG+ +L I ++ +
Sbjct: 474 YVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQ 533
Query: 448 ADSIRITWKATLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICM 507
A+S+ ++WKA+ + W + + + D Y LT L P + Y IC+
Sbjct: 534 ANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICI 593
>gi|4826876 osteomodulin [Homo sapiens]
Length = 421
Score = 108 bits (269), Expect = 2e-23
Identities = 67/205 (32%), Positives = 111/205 (54%), Gaps = 2/205 (0%)
Query: 124 NLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLF 183
N+P +++L+LQ N + + +S L++++L N + + I+ FA L L
Sbjct: 88 NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLH 147
Query: 184 LSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDT 243
L N+L P LP +LE L L N IS + +A GL +L L L N L + + D
Sbjct: 148 LEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKI 207
Query: 244 FSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSN 303
F++++ L +L+L N L + P LPS+ L L L++N+IS IP K+ +L L +S+
Sbjct: 208 FAKMEKLMQLNLCSNRLESMPPGLPSS-LMYLSLENNSISSIPEKYFDKLPKLHTLRMSH 266
Query: 304 NNLTTLPRGLFDDLGNLAQLLLRNN 328
N L +P +F +L N+ +L + +N
Sbjct: 267 NKLQDIPYNIF-NLPNIVELSVGHN 290
Score = 93.6 bits (231), Expect = 5e-19
Identities = 83/257 (32%), Positives = 125/257 (48%), Gaps = 34/257 (13%)
Query: 54 CPSVCRCDNGF---IYCNDRGLTSIPADIPDDATTLYLQ--------------------- 89
C S C C F +YC++R L +IP +IP LYLQ
Sbjct: 62 CVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEI 120
Query: 90 ---NNQINNAGIPQDLKTKV-NVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARD 145
+N+I + I + K+ N+ ++L N+L+EFP LP+SL L L N + + +
Sbjct: 121 NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTN 180
Query: 146 SLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRL 205
++ + L L L N + +++ FA ++L L L N L S+P GLP +L L L
Sbjct: 181 AMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSL 240
Query: 206 DDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPL 265
++N IS+IP F L L L + N L Q I + F+ L N+ ELS+ N L
Sbjct: 241 ENNSISSIPEKYFDKLPKLHTLRMSHNKL--QDIPYNIFN-LPNIVELSVGHNKL-KQAF 296
Query: 266 NLPSAHLQKLYLQDNAI 282
+P +L+ LYLQ+N I
Sbjct: 297 YIP-RNLEHLYLQNNEI 312
>gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo
sapiens]
Length = 581
Score = 107 bits (266), Expect = 5e-23
Identities = 96/352 (27%), Positives = 161/352 (45%), Gaps = 16/352 (4%)
Query: 54 CPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYL 113
CP CRC+ +YC + L IP+ I L L+ N + Q K + +YL
Sbjct: 34 CPKGCRCEGKMVYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQ-FKGLNQLTWLYL 92
Query: 114 YEN---DLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEE 170
N ++DE N R L+EL L N + ++ + L L L N + ++ E+
Sbjct: 93 DHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQ 152
Query: 171 DAFADSKQLKLLFLSRNHLSSIPSGL---PHTLEELRLDDNRISTIPLHAFKGLNSLRRL 227
F ++L L L N L +IP + LE L L NRI ++ + F G+ L+ L
Sbjct: 153 --FRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKEL 210
Query: 228 VLDGNLLANQRIADDTFSRLQNLTELSLVRN--SLAAPPLNLPSAHLQKLYLQDNAISHI 285
L+ N + +A F RL +L L L N S+ ++ + LQ+L L N I
Sbjct: 211 HLEHNQFSKLNLA--LFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAF 268
Query: 286 PYNTLAK-MRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVK 344
++ + + L+RL+L +N LT + + + D +L + L N W C N+ L +W+K
Sbjct: 269 SGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNICSLVNWLK 328
Query: 345 ARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFE-TGPQGGVANAAAKTT 395
+ + ++C P++++G+ + D C + T + +A A K T
Sbjct: 329 SFKG-LRENTIICASPKELQGVNVIDAVKNYSICGKSTTERFDLARALPKPT 379
>gi|153251229 chondroadherin precursor [Homo sapiens]
Length = 359
Score = 106 bits (265), Expect = 6e-23
Identities = 104/371 (28%), Positives = 153/371 (41%), Gaps = 64/371 (17%)
Query: 31 LRDWLFLCYGLIAFLTEVIDSTTCPSVCRC--DNGFIYCNDRGLTSIPADIPDDATTLYL 88
+R L L GL+A L + CP C C D + C+ GL IP + + L L
Sbjct: 2 VRPMLLLSLGLLAGLLPAL--AACPQNCHCHSDLQHVICDKVGLQKIPK-VSEKTKLLNL 58
Query: 89 QNNQINNAGIPQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLA 148
Q N L N P +L LHLQ +R +A +
Sbjct: 59 QRNNFP-----------------VLAANSFRAMP-----NLVSLHLQHCQIREVAAGAFR 96
Query: 149 RIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEEL---RL 205
+ L L+L N + + AF D +L L+L N ++ +P GL L L +L
Sbjct: 97 GLKQLIYLYLSHNDIRV--LRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQL 154
Query: 206 DDNRISTIPLHAFKGLNSLRRLVLDGNLLANQR--IADDT-------------------- 243
++N+I + AF+G LR L L N L++ + DD
Sbjct: 155 NNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAA 214
Query: 244 FSRLQNLTELSLVRNSLAAPPLNLPSA---HLQKLYLQDNAISHIPYNTLAKMRELERLD 300
S+L+ + EL L N L + P N + +L+ L+L + + + L+ +
Sbjct: 215 LSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVH 274
Query: 301 LSNNNLTTLPRGL-FDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQG 359
L NN L LP FD L LA L NNPW C C L LR W++A+A+ + C
Sbjct: 275 LENNRLNQLPSNFPFDSLETLA---LTNNPWKCTCQLRGLRRWLEAKASRPDA---TCAS 328
Query: 360 PEKVRGMAIKD 370
P K +G I+D
Sbjct: 329 PAKFKGQHIRD 339
>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
Length = 699
Score = 105 bits (261), Expect = 2e-22
Identities = 89/278 (32%), Positives = 125/278 (44%), Gaps = 27/278 (9%)
Query: 55 PSVCRCDNGFIYCNDRGLTSIP-----------------ADIPDDATT-------LYLQN 90
PS C I C + LT IP A IPD+A L L
Sbjct: 317 PSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSK 376
Query: 91 NQINNAGI-PQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLAR 149
N I ++GI P+ K + + + N+L + P LP +L EL + +NN++ I +SL+
Sbjct: 377 NNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSD 436
Query: 150 IPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNR 209
+ L L L+ N++S ++ AF K L L L +N IP GLP ++EEL L++N+
Sbjct: 437 LNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQ 496
Query: 210 ISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPS 269
I I F + +VL N + RIA + +NL + L N L P LP
Sbjct: 497 IEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPK 556
Query: 270 AHLQKLYLQDNAISHIPYNTLAKMRE-LERLDLSNNNL 306
+ L L L N I IP M LE L LS N L
Sbjct: 557 S-LLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKL 593
Score = 43.5 bits (101), Expect = 6e-04
Identities = 65/297 (21%), Positives = 105/297 (35%), Gaps = 78/297 (26%)
Query: 68 NDRGLTSIPADIPDDAT---TLYLQNNQINNAGI-PQDLKTKVNVQVIYLYENDLDEFPI 123
N+ L +I + D TL L+ N ++ A + P K ++ + L +N P
Sbjct: 422 NENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ 481
Query: 124 NLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLF 183
LP S+ EL+L++N + I + + L N + I A+ + + L+ +
Sbjct: 482 GLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESID 541
Query: 184 LSRNHLSSIPSGLP---------------------------------------------- 197
LS N L +PS LP
Sbjct: 542 LSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRV 601
Query: 198 ------HTLEELRLDDNRISTIP--LHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQN 249
H+L EL LD N + +IP + K L+ LR L N +I + + N
Sbjct: 602 SFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLR--------LNNNKIRNILPEEICN 653
Query: 250 LTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNL 306
E NL HL+ Y++ I IP T + +R + L N+
Sbjct: 654 AEE---------DDDSNLEHLHLENNYIK---IREIPSYTFSCIRSYSSIVLKPQNI 698
Score = 37.0 bits (84), Expect = 0.059
Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 263 PPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQ 322
PPL P + L L N+I+ IP + LERLDLS NN+T+ G+ L +
Sbjct: 338 PPLTAPQ--ITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITS--SGIGPKAFKLLK 393
Query: 323 LLLRNN 328
L+R N
Sbjct: 394 KLMRLN 399
>gi|229089140 leucine rich repeat containing 24 [Homo sapiens]
Length = 513
Score = 104 bits (260), Expect = 2e-22
Identities = 82/254 (32%), Positives = 116/254 (45%), Gaps = 50/254 (19%)
Query: 122 PINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKL 181
P+ +P + L LQDNN+ + +LA + L +L+L +NS+ ++E AF +L
Sbjct: 45 PLGIPPGTQTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLR--ALEAGAFRAQPRLLE 102
Query: 182 LFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIAD 241
L L+ N L + SG AF GL LR L L GN LA R+ D
Sbjct: 103 LALTSNRLRGLRSG---------------------AFVGLAQLRVLYLAGNQLA--RLLD 139
Query: 242 DTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDL 301
TF L+LP LQ+L+LQ+N+I + LA + L LDL
Sbjct: 140 FTF--------------------LHLP--RLQELHLQENSIELLEDQALAGLSSLALLDL 177
Query: 302 SNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVK---ARAAVVNVRGLMCQ 358
S N L T+ R L +L L L NPW C C L WL W+K R R +MC
Sbjct: 178 SRNQLGTISREALQPLASLQVLRLTENPWRCDCALHWLGAWIKEGGQRLLTSRDRKIMCA 237
Query: 359 GPEKVRGMAIKDIT 372
P ++ ++ D++
Sbjct: 238 EPPRLALQSLLDVS 251
Score = 68.9 bits (167), Expect = 1e-11
Identities = 76/260 (29%), Positives = 113/260 (43%), Gaps = 43/260 (16%)
Query: 54 CPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYL 113
CP+ CRC + + C L +P IP TL+LQ+N I P L ++ +YL
Sbjct: 23 CPAACRCYSATVECGALRLRVVPLGIPPGTQTLFLQDNNIARLE-PGALAPLAALRRLYL 81
Query: 114 YENDLDEFPINLPRS---LRELHLQDNNVR----------------TIARDSLAR----- 149
+ N L R+ L EL L N +R +A + LAR
Sbjct: 82 HNNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLARLLDFT 141
Query: 150 ---IPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLD 206
+P L++LHL +NS+ +E+ A A L LL LSRN L +I L L++
Sbjct: 142 FLHLPRLQELHLQENSIEL--LEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQV- 198
Query: 207 DNRISTIPLHAFKGLNSLRRLVLDG--NLLANQ----RIADDTFSRLQNLTELSLVRNSL 260
R++ P L+ L + +G LL ++ A+ LQ+L ++S +SL
Sbjct: 199 -LRLTENPWRCDCALHWLGAWIKEGGQRLLTSRDRKIMCAEPPRLALQSLLDVS--HSSL 255
Query: 261 AAPPLNLPSAHLQKLYLQDN 280
P PS H+Q L L N
Sbjct: 256 ICIP---PSVHVQPLELTAN 272
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,080,154
Number of Sequences: 37866
Number of extensions: 1104740
Number of successful extensions: 5845
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 203
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 3222
Number of HSP's gapped (non-prelim): 1140
length of query: 674
length of database: 18,247,518
effective HSP length: 109
effective length of query: 565
effective length of database: 14,120,124
effective search space: 7977870060
effective search space used: 7977870060
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.