BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo sapiens] (1082 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 2104 0.0 gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 1276 0.0 gi|71773106 adaptor-related protein complex 2, beta 1 subunit is... 280 7e-75 gi|4557469 adaptor-related protein complex 2, beta 1 subunit iso... 280 7e-75 gi|22027651 adaptor-related protein complex 1 beta 1 subunit iso... 279 9e-75 gi|22027653 adaptor-related protein complex 1 beta 1 subunit iso... 279 9e-75 gi|166197671 adaptor-related protein complex 4, beta 1 subunit [... 179 1e-44 gi|55741677 SET domain containing 1A [Homo sapiens] 71 6e-12 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 70 1e-11 gi|221316632 coatomer protein complex, subunit beta 1 [Homo sapi... 69 3e-11 gi|221316630 coatomer protein complex, subunit beta 1 [Homo sapi... 69 3e-11 gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens] 69 3e-11 gi|210032580 SET domain containing 1B [Homo sapiens] 68 5e-11 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 67 1e-10 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 67 1e-10 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 1e-10 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 1e-10 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 1e-10 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 1e-10 gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 1e-10 gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 64 6e-10 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 64 8e-10 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 61 5e-09 gi|115529449 upstream binding transcription factor, RNA polymera... 61 7e-09 gi|115529451 upstream binding transcription factor, RNA polymera... 61 7e-09 gi|7657671 upstream binding transcription factor, RNA polymerase... 61 7e-09 gi|217330641 IWS1 homolog [Homo sapiens] 60 1e-08 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 59 3e-08 gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 58 4e-08 gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 58 4e-08 >gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo sapiens] Length = 1082 Score = 2104 bits (5452), Expect = 0.0 Identities = 1082/1082 (100%), Positives = 1082/1082 (100%) Query: 1 MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKR 60 MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKR Sbjct: 1 MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKR 60 Query: 61 IVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLK 120 IVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLK Sbjct: 61 IVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLK 120 Query: 121 DPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQK 180 DPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQK Sbjct: 121 DPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQK 180 Query: 181 DQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVII 240 DQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVII Sbjct: 181 DQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVII 240 Query: 241 SMLTRYARTQFLSPTQNESLLEENAEKAFYGSEEDEAKGAGSEETAAAAAPSRKPYVMDP 300 SMLTRYARTQFLSPTQNESLLEENAEKAFYGSEEDEAKGAGSEETAAAAAPSRKPYVMDP Sbjct: 241 SMLTRYARTQFLSPTQNESLLEENAEKAFYGSEEDEAKGAGSEETAAAAAPSRKPYVMDP 300 Query: 301 DHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQ 360 DHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQ Sbjct: 301 DHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQ 360 Query: 361 NVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRS 420 NVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRS Sbjct: 361 NVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRS 420 Query: 421 MDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQ 480 MDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQ Sbjct: 421 MDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQ 480 Query: 481 HGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQ 540 HGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQ Sbjct: 481 HGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQ 540 Query: 541 VINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAK 600 VINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAK Sbjct: 541 VINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAK 600 Query: 601 KLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPE 660 KLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPE Sbjct: 601 KLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPE 660 Query: 661 WTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDN 720 WTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDN Sbjct: 661 WTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDN 720 Query: 721 EDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESE 780 EDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESE Sbjct: 721 EDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESE 780 Query: 781 EEQLEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSLAADLEGLT 840 EEQLEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSLAADLEGLT Sbjct: 781 EEQLEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSLAADLEGLT 840 Query: 841 LTDSTLVPSLLSPVSGVGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSD 900 LTDSTLVPSLLSPVSGVGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSD Sbjct: 841 LTDSTLVPSLLSPVSGVGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSD 900 Query: 901 TPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAVMGINFCDSTQAANFQLCTQTRQF 960 TPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAVMGINFCDSTQAANFQLCTQTRQF Sbjct: 901 TPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAVMGINFCDSTQAANFQLCTQTRQF 960 Query: 961 YVSIQPPVGELMAPVFMSENEFKKEQGKLMGMNEITEKLMLPDTCRSDHIVVQKVTATAN 1020 YVSIQPPVGELMAPVFMSENEFKKEQGKLMGMNEITEKLMLPDTCRSDHIVVQKVTATAN Sbjct: 961 YVSIQPPVGELMAPVFMSENEFKKEQGKLMGMNEITEKLMLPDTCRSDHIVVQKVTATAN 1020 Query: 1021 LGRVPCGTSDEYRFAGRTLTGGSLVLLTLDARPAGAAQLTVNSEKMVIGTMLVKDVIQAL 1080 LGRVPCGTSDEYRFAGRTLTGGSLVLLTLDARPAGAAQLTVNSEKMVIGTMLVKDVIQAL Sbjct: 1021 LGRVPCGTSDEYRFAGRTLTGGSLVLLTLDARPAGAAQLTVNSEKMVIGTMLVKDVIQAL 1080 Query: 1081 TQ 1082 TQ Sbjct: 1081 TQ 1082 >gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo sapiens] Length = 1094 Score = 1276 bits (3301), Expect = 0.0 Identities = 686/1105 (62%), Positives = 829/1105 (75%), Gaps = 48/1105 (4%) Query: 7 YSEDKGGSAGPGEPEYGHDPASG-------GIFSSDYKRHDDLKEMLDTNKDSLKLEAMK 59 Y+E GG E G + S G+FSSD K+++DLK+ML++NKDS KL+AMK Sbjct: 8 YNEQSGGGEAT---ELGQEATSTISPSGAFGLFSSDLKKNEDLKQMLESNKDSAKLDAMK 64 Query: 60 RIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGL 119 RIV MIA+GKNAS+LFPAVVKNVA KNIE+KKLVYVYLVRYAEEQQDLALLSISTFQR L Sbjct: 65 RIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRAL 124 Query: 120 KDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQ 179 KDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEA++D+SPYVRK AAHAI KLYSLD +Q Sbjct: 125 KDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPEQ 184 Query: 180 KDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVI 239 K+ LIEVIEKLL DK+TLVAGSVVMAFEEVCP+RIDLIHKNYRKLCNLL+DVEEWGQVVI Sbjct: 185 KEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVI 244 Query: 240 ISMLTRYARTQFLSPTQNESLLEENAEKAFYGSEEDEAKGAGSEETAAAAAPSRKPYVMD 299 I MLTRYARTQF+SP + LE+N K FY S++D+ + + +KPY MD Sbjct: 245 IHMLTRYARTQFVSPWKEGDELEDNG-KNFYESDDDQKEKTDKK---------KKPYTMD 294 Query: 300 PDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVL 359 PDHRLL+RNTKPLLQSR+AAVVMAVAQLY+H++PK+E G+I+K+LVRLLRS+ EVQY+VL Sbjct: 295 PDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHISPKSEAGIISKSLVRLLRSNREVQYIVL 354 Query: 360 QNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIR 419 QN+ATMSI+R+GMFEPYLKSFY+RSTDPT IK LKLE+LTNLANE NI T+LREFQTY++ Sbjct: 355 QNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVK 414 Query: 420 SMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPA 479 S DK F AATIQ IGRCATNI V DTCLNGLV LLSNRDE+VVAESVVVIKKLLQMQPA Sbjct: 415 SQDKQFAAATIQTIGRCATNILEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPA 474 Query: 480 QHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKL 539 QHGEIIKH+AKL D+I VP+ARASILWLIGE CE VP+IAPDVLRKMAKSFT+E+D+VKL Sbjct: 475 QHGEIIKHMAKLLDSITVPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKL 534 Query: 540 QVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHA 599 Q++NL AKLYLTNSKQTKLLTQY+L+L KYDQNYDIRDR RF RQLIVP+ + GALS++A Sbjct: 535 QILNLGAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNVKSGALSKYA 594 Query: 600 KKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEV- 658 KK+FLA KPAP+LES FKDRDHFQLG+LSH LN KATGY EL +WPE APDPSVRNVEV Sbjct: 595 KKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNIKATGYLELSNWPEVAPDPSVRNVEVI 654 Query: 659 ---PEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESS 715 EWT + + K++ K FYS+SE E +S+DS +SESES S+S + SGE Sbjct: 655 ELAKEWTP-AGKAKQENSAKKFYSESEEEE---DSSDSSSDSESESGSESGEQGESGEEG 710 Query: 716 SESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASS------------SDEG 763 NED ED + SES + ++T K+ + KG++ S SD Sbjct: 711 --DSNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSS 768 Query: 764 SDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKS-----APATKEISLLDLEDFTPPS 818 +D SSS +S SESE E + R T K P TK++SLLDL+DF P S Sbjct: 769 NDESSSIEDSSSDSESESEPESESESRRVTKEKEKKTKQDRTPLTKDVSLLDLDDFNPVS 828 Query: 819 VQPVSPPAIVSTSLAADLEGLTLTDSTLVPSLLSPVSGVGRQE-LLHRVAGEGLAVDYTF 877 P +S SL ADLEGL L+ S+ V S+ +P + LLHR++G+GLA Y F Sbjct: 829 TPVALPTPALSPSLMADLEGLHLSTSSSVISVSTPAFVPTKTHVLLHRMSGKGLAAHYFF 888 Query: 878 SRQPFSGDPHMVSVHIHFSNSSDTPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAV 937 RQP MVS+ I +N++D I+ +H+G KLP G+ + F I+SL P S T Sbjct: 889 PRQPCIFGDKMVSIQITLNNTTDRKIENIHIGEKKLPIGMKMHVFNPIDSLEPEGSITVS 948 Query: 938 MGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGKLMGMNEITE 997 MGI+FCDSTQ A+FQLCT+ F V+IQPPVGEL+ PV MSE +FKKEQG L GMNE + Sbjct: 949 MGIDFCDSTQTASFQLCTKDDCFNVNIQPPVGELLLPVAMSEKDFKKEQGVLTGMNETSA 1008 Query: 998 KLMLPDTCRSDHIVVQKVTATANLGRVPCGTSDEYRFAGRTLTGGSLVLLTLDARPAGAA 1057 ++ + ++ QKV AN+G VP G + +RFA +T+ GSL+L+T++ + A Sbjct: 1009 VIIAAPQNFTPSVIFQKVVNVANVGAVPSGQDNIHRFAAKTVHSGSLMLVTVELKEGSTA 1068 Query: 1058 QLTVNSEKMVIGTMLVKDVIQALTQ 1082 QL +N+EK VIG++L++++ L+Q Sbjct: 1069 QLIINTEKTVIGSVLLRELKPVLSQ 1093 >gi|71773106 adaptor-related protein complex 2, beta 1 subunit isoform a [Homo sapiens] Length = 951 Score = 280 bits (715), Expect = 7e-75 Identities = 188/621 (30%), Positives = 313/621 (50%), Gaps = 75/621 (12%) Query: 41 DLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRY 100 +LK L+ K + EA+K+++A + GK+ S LFP VV + N+E+KKLVY+YL+ Y Sbjct: 17 ELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNY 76 Query: 101 AEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPY 160 A+ Q D+A++++++F + +DPN LIRA A+R + IRV I + +++ D PY Sbjct: 77 AKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPY 136 Query: 161 VRKTAAHAIPKLYSLDSDQ-KDQ-LIEVIEKLLADKTTLVAGSVVMAFEEVCPER----- 213 VRKTAA + KL+ +++ +DQ ++ + L+AD +V + V A E+ Sbjct: 137 VRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNL 196 Query: 214 IDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENAEKAFYGSE 273 +DL +N KL L + EWGQ+ I+ L+ Y + Sbjct: 197 LDLNPQNINKLLTALNECTEWGQIFILDCLSNY-------------------------NP 231 Query: 274 EDEAKGAGSEETAAAAAPSRKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQL--YFHL 331 +D+ + E R T L + SA V+ AV L + L Sbjct: 232 KDDREAQSICE----------------------RVTPRLSHANSAVVLSAVKVLMKFLEL 269 Query: 332 APKAE------VGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRST 385 PK + +A LV LL EVQYV L+N+ + KR + + +K F+++ Sbjct: 270 LPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYN 329 Query: 386 DPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRD 445 DP +K+ KL+++ LA++ NI VL E + Y +D DFV ++AIGRCA + + + Sbjct: 330 DPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAE 389 Query: 446 TCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASIL 505 C++ L+ L+ + VV E++VVI+ + + P ++ II L + D++ P ARA+++ Sbjct: 390 RCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMI 449 Query: 506 WLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLS 565 W++GEY E + A ++L + F E V+L ++ KL+L +T+ L Q VLS Sbjct: 450 WIVGEYAERIDN-ADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLS 508 Query: 566 LAKYD-QNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKP-----APVLESSFKDR 619 LA D N D+RDR +L+ AK++ L+ KP ++E + D Sbjct: 509 LATQDSDNPDLRDRGYIYWRLLSTDPV------TAKEVVLSEKPLISEETDLIEPTLLDE 562 Query: 620 DHFQLGSLSHLLNAKATGYQE 640 +GSL+ + + + E Sbjct: 563 LICHIGSLASVYHKPPNAFVE 583 >gi|4557469 adaptor-related protein complex 2, beta 1 subunit isoform b [Homo sapiens] Length = 937 Score = 280 bits (715), Expect = 7e-75 Identities = 188/621 (30%), Positives = 313/621 (50%), Gaps = 75/621 (12%) Query: 41 DLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRY 100 +LK L+ K + EA+K+++A + GK+ S LFP VV + N+E+KKLVY+YL+ Y Sbjct: 17 ELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNY 76 Query: 101 AEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPY 160 A+ Q D+A++++++F + +DPN LIRA A+R + IRV I + +++ D PY Sbjct: 77 AKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPY 136 Query: 161 VRKTAAHAIPKLYSLDSDQ-KDQ-LIEVIEKLLADKTTLVAGSVVMAFEEVCPER----- 213 VRKTAA + KL+ +++ +DQ ++ + L+AD +V + V A E+ Sbjct: 137 VRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNL 196 Query: 214 IDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENAEKAFYGSE 273 +DL +N KL L + EWGQ+ I+ L+ Y + Sbjct: 197 LDLNPQNINKLLTALNECTEWGQIFILDCLSNY-------------------------NP 231 Query: 274 EDEAKGAGSEETAAAAAPSRKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQL--YFHL 331 +D+ + E R T L + SA V+ AV L + L Sbjct: 232 KDDREAQSICE----------------------RVTPRLSHANSAVVLSAVKVLMKFLEL 269 Query: 332 APKAE------VGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRST 385 PK + +A LV LL EVQYV L+N+ + KR + + +K F+++ Sbjct: 270 LPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYN 329 Query: 386 DPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRD 445 DP +K+ KL+++ LA++ NI VL E + Y +D DFV ++AIGRCA + + + Sbjct: 330 DPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAE 389 Query: 446 TCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASIL 505 C++ L+ L+ + VV E++VVI+ + + P ++ II L + D++ P ARA+++ Sbjct: 390 RCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMI 449 Query: 506 WLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLS 565 W++GEY E + A ++L + F E V+L ++ KL+L +T+ L Q VLS Sbjct: 450 WIVGEYAERIDN-ADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLS 508 Query: 566 LAKYD-QNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKP-----APVLESSFKDR 619 LA D N D+RDR +L+ AK++ L+ KP ++E + D Sbjct: 509 LATQDSDNPDLRDRGYIYWRLLSTDPV------TAKEVVLSEKPLISEETDLIEPTLLDE 562 Query: 620 DHFQLGSLSHLLNAKATGYQE 640 +GSL+ + + + E Sbjct: 563 LICHIGSLASVYHKPPNAFVE 583 >gi|22027651 adaptor-related protein complex 1 beta 1 subunit isoform a [Homo sapiens] Length = 949 Score = 279 bits (714), Expect = 9e-75 Identities = 184/613 (30%), Positives = 317/613 (51%), Gaps = 59/613 (9%) Query: 41 DLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRY 100 +LK L+++K K EA+K+++A + GK+ S LFP VV + N+E+KKLVY+YL+ Y Sbjct: 17 ELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNY 76 Query: 101 AEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPY 160 A+ Q D+A+++++TF + +DPN LIRA A+R + IRV I + +++ D PY Sbjct: 77 AKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPY 136 Query: 161 VRKTAAHAIPKLYSLDSDQ-KDQ-LIEVIEKLLADKTTLVAGSVVMAFEEVCPER----- 213 VRKTAA + KL+ +++ +DQ ++ ++ L++D +V + V A E+ Sbjct: 137 VRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHPSSNL 196 Query: 214 IDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENAEKAFYGSE 273 +DL ++ KL L + EWGQ+ I+ L Y + Sbjct: 197 LDLNPQSINKLLTALNECTEWGQIFILDCLANYMP-----------------------KD 233 Query: 274 EDEAKGAGSEETAAAAAPSRKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAP 333 + EA+ T P + + ++L K L++ ++ Y L Sbjct: 234 DREAQSICERVT---------PRLSHANSAVVLSAVKVLMKFME--MLSKDLDYYGTLLK 282 Query: 334 KAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKIL 393 K +A LV LL + E+QYV L+N+ + KR + + +K F+++ DP +K+ Sbjct: 283 K-----LAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVFFVKYNDPIYVKLE 337 Query: 394 KLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQ 453 KL+++ LA++ NI VL E + Y +D DFV ++AIGRCA + + + C++ L+ Sbjct: 338 KLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLD 397 Query: 454 LLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCE 513 L+ + VV E++VVIK + + P ++ +I L + D++ P ARA+++W++GEY E Sbjct: 398 LIQTKVNYVVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAE 457 Query: 514 HVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYD-QN 572 + A ++L + F E V+LQ++ KL+L +T+ L Q VLSLA D N Sbjct: 458 RIDN-ADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSLATQDSDN 516 Query: 573 YDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKP-----APVLESSFKDRDHFQLGSL 627 D+RDR +L+ AK++ LA KP ++E + D +G+L Sbjct: 517 PDLRDRGYIYWRLLSTDPVA------AKEVVLAEKPLISEETDLIEPTLLDELICYIGTL 570 Query: 628 SHLLNAKATGYQE 640 + + + + + E Sbjct: 571 ASVYHKPPSAFVE 583 >gi|22027653 adaptor-related protein complex 1 beta 1 subunit isoform b [Homo sapiens] Length = 942 Score = 279 bits (714), Expect = 9e-75 Identities = 184/613 (30%), Positives = 317/613 (51%), Gaps = 59/613 (9%) Query: 41 DLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRY 100 +LK L+++K K EA+K+++A + GK+ S LFP VV + N+E+KKLVY+YL+ Y Sbjct: 17 ELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNY 76 Query: 101 AEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPY 160 A+ Q D+A+++++TF + +DPN LIRA A+R + IRV I + +++ D PY Sbjct: 77 AKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPY 136 Query: 161 VRKTAAHAIPKLYSLDSDQ-KDQ-LIEVIEKLLADKTTLVAGSVVMAFEEVCPER----- 213 VRKTAA + KL+ +++ +DQ ++ ++ L++D +V + V A E+ Sbjct: 137 VRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHPSSNL 196 Query: 214 IDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENAEKAFYGSE 273 +DL ++ KL L + EWGQ+ I+ L Y + Sbjct: 197 LDLNPQSINKLLTALNECTEWGQIFILDCLANYMP-----------------------KD 233 Query: 274 EDEAKGAGSEETAAAAAPSRKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAP 333 + EA+ T P + + ++L K L++ ++ Y L Sbjct: 234 DREAQSICERVT---------PRLSHANSAVVLSAVKVLMKFME--MLSKDLDYYGTLLK 282 Query: 334 KAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKIL 393 K +A LV LL + E+QYV L+N+ + KR + + +K F+++ DP +K+ Sbjct: 283 K-----LAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVFFVKYNDPIYVKLE 337 Query: 394 KLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQ 453 KL+++ LA++ NI VL E + Y +D DFV ++AIGRCA + + + C++ L+ Sbjct: 338 KLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLD 397 Query: 454 LLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCE 513 L+ + VV E++VVIK + + P ++ +I L + D++ P ARA+++W++GEY E Sbjct: 398 LIQTKVNYVVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAE 457 Query: 514 HVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYD-QN 572 + A ++L + F E V+LQ++ KL+L +T+ L Q VLSLA D N Sbjct: 458 RIDN-ADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSLATQDSDN 516 Query: 573 YDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKP-----APVLESSFKDRDHFQLGSL 627 D+RDR +L+ AK++ LA KP ++E + D +G+L Sbjct: 517 PDLRDRGYIYWRLLSTDPVA------AKEVVLAEKPLISEETDLIEPTLLDELICYIGTL 570 Query: 628 SHLLNAKATGYQE 640 + + + + + E Sbjct: 571 ASVYHKPPSAFVE 583 >gi|166197671 adaptor-related protein complex 4, beta 1 subunit [Homo sapiens] Length = 739 Score = 179 bits (455), Expect = 1e-44 Identities = 145/568 (25%), Positives = 257/568 (45%), Gaps = 71/568 (12%) Query: 58 MKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQR 117 ++R++ + +G + S +F +VK A +I KKLVY+Y+ YA + DLALL+I+T + Sbjct: 33 IQRVIRYMTQGLDMSGVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALLAINTLCK 92 Query: 118 GLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSL-- 175 DPN ++R ALR + S+R+P + + I D + YVR+ A K+++L Sbjct: 93 DCSDPNPMVRGLALRSMCSLRMPGVQEYIQQPILNGLRDKASYVRRVAVLGCAKMHNLHG 152 Query: 176 DSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKN--YRKLCNLLIDVEE 233 DS+ L+ + LL D+ +V + + + EE+ + ++ L N + +++ Sbjct: 153 DSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQEGGVVINKPIAHHLLNRMSKLDQ 212 Query: 234 WGQVVIISMLTRYARTQFLSPTQNESLLEENAEKAFYGSEEDEAKGAGSEETAAAAAPSR 293 WGQ +++ L RY P E L + Sbjct: 213 WGQAEVLNFLLRY------QPRSEEELFD------------------------------- 235 Query: 294 KPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLA---PKAEVGVIAKALVRLLRS 350 +L L+S S VVM +L+ LA P + V+ + LL + Sbjct: 236 -----------ILNLLDSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAA 284 Query: 351 HS----EVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETN 406 S E+ +V L +V + G F + K F+ ++P IK+ K+EVL L N+ N Sbjct: 285 CSSESRELCFVALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDEN 344 Query: 407 IPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAES 466 + VL E + Y + DF A I AIG A D C+ L +LL R E + Sbjct: 345 VQQVLEELRGYCTDVSADFAQAAIFAIGGIART---YTDQCVQILTELLGLRQEHITTVV 401 Query: 467 VVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKM 526 V + L+ + P + + L +NIQ + +++WL+G + E +P AP VL Sbjct: 402 VQTFRDLVWLCPQCTEAVCQALPGCEENIQDSEGKQALIWLLGVHGERIPN-APYVLEDF 460 Query: 527 AKSFTAEE-DIVKLQVINLAAKLYLTNSKQTK-LLTQYVLSLAKYDQNYDIRDRARFTRQ 584 ++ +E VK++++ +L+L+ + + +L + + + +++ +RDR F + Sbjct: 461 VENVKSETFPAVKMELLTALLRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYR 520 Query: 585 LIVPSEQGGALSRHAKKLFLAPKPAPVL 612 L++ K++ +PK P L Sbjct: 521 LLLVGID------EVKRILCSPKSDPTL 542 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 70.9 bits (172), Expect = 6e-12 Identities = 55/192 (28%), Positives = 86/192 (44%), Gaps = 10/192 (5%) Query: 642 PDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESES 701 P+ +EA +P + P+ + + + K + K F DSEGE ES+ E + E Sbjct: 925 PEQEKEAGEPGRPGTKPPKRDEERGKTQGKHR-KSFALDSEGEEASQESSSEKDEEDDEE 983 Query: 702 DSKSSSESGSGESSSESDNEDQDEDEEKGRGSE-SEQSEEDGKRKTKKKVPERKGEASSS 760 D + + +++ + EDEE S+ S ++ DG+ + +SSS Sbjct: 984 DEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSS 1043 Query: 761 DEGSDSSS--SSSESEMTSESEEEQLEPASWSRKTPPSSK---SAPATKEISLLDL---E 812 S SSS SSS SE +SE EEE+ PA+ +PP + PA E+ + + Sbjct: 1044 SSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGS 1103 Query: 813 DFTPPSVQPVSP 824 TP Q SP Sbjct: 1104 PVTPLPEQEASP 1115 Score = 57.8 bits (138), Expect = 6e-08 Identities = 63/236 (26%), Positives = 84/236 (35%), Gaps = 45/236 (19%) Query: 637 GYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDS-----EGESGPTESA 691 G LP + + +PS E+ E ++ EKR P D E E+G Sbjct: 886 GALRLPSFKVKRKEPS----EISE----ASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRP 937 Query: 692 DSDPESESESDSK------------SSSESGSGESSSESDNEDQDEDEE----------- 728 + P E K S E S ESSSE D ED +EDEE Sbjct: 938 GTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTT 997 Query: 729 --KGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEP 786 + S+ E E D K + GE S+ + SSSSSS S +S S Sbjct: 998 KKETEVSDGEDEESDSSSKCSLYA-DSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSS 1056 Query: 787 ASWSRKTPPSSKSAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSLAADLEGLTLT 842 +S S + PA + PP PV PA V + + G +T Sbjct: 1057 SSESSSEDEEEEERPAALPSA------SPPPREVPVPTPAPVEVPVPERVAGSPVT 1106 Score = 32.7 bits (73), Expect = 1.9 Identities = 36/167 (21%), Positives = 56/167 (33%), Gaps = 18/167 (10%) Query: 678 YSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQ 737 ++ + P S S P S+ + S S++ + SE+ +D S S Sbjct: 263 FTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDAFSRRHFSASSASTT 322 Query: 738 SEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSES-------------EEEQL 784 + T +S S S SSSSSS +S++ Sbjct: 323 ASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSY 382 Query: 785 EPASWSRKTPPSSKSAPATKEISLLDLEDFTP-----PSVQPVSPPA 826 P +R+ PP + A T E + P P+ Q PPA Sbjct: 383 PPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPA 429 Score = 30.4 bits (67), Expect = 9.4 Identities = 19/76 (25%), Positives = 31/76 (40%), Gaps = 9/76 (11%) Query: 726 DEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLE 785 + E+ + + +Q E+G E +GE +E +SS SSS S+ L Sbjct: 1345 EAEEPKPQQLQQQREEG---------EEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLR 1395 Query: 786 PASWSRKTPPSSKSAP 801 + R+ PP P Sbjct: 1396 SHARRRRPPPPPPPPP 1411 Score = 30.4 bits (67), Expect = 9.4 Identities = 15/41 (36%), Positives = 18/41 (43%) Query: 672 EKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSG 712 E+ KP + E G E + E E ES SSS G G Sbjct: 1347 EEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEG 1387 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 69.7 bits (169), Expect = 1e-11 Identities = 50/168 (29%), Positives = 77/168 (45%), Gaps = 2/168 (1%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQ-DEDEEKGRGSESEQ 737 SDS + ++S SD +S SDS SS S S +SS SD+ D D + S+S + Sbjct: 569 SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628 Query: 738 SEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSS 797 SE D K + SSD SDSS SS+ S + S+ +S S + SS Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDN-SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687 Query: 798 KSAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSLAADLEGLTLTDST 845 S+ ++ + + D + S S + S S ++D + +DS+ Sbjct: 688 DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735 Score = 68.9 bits (167), Expect = 2e-11 Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 2/142 (1%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S+DS SES S SS+ S S +SS SD+ D + + S+S S Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123 Query: 739 EE--DGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPS 796 + D + ++S S E SDSS SS S+ + S+ +S S + S Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183 Query: 797 SKSAPATKEISLLDLEDFTPPS 818 S S+ ++ D D + S Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSS 1205 Score = 67.4 bits (163), Expect = 7e-11 Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 1/140 (0%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S+DS S+S S SS S S +SS SD+ D + + S+S +S Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSES 1084 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 D + ++S S + SDSS SS S+ ++ S+ +S S + SS Sbjct: 1085 -SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143 Query: 799 SAPATKEISLLDLEDFTPPS 818 S+ +++ D D + S Sbjct: 1144 SSDSSESSDSSDSSDSSDSS 1163 Score = 67.4 bits (163), Expect = 7e-11 Identities = 42/145 (28%), Positives = 66/145 (45%), Gaps = 5/145 (3%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S+DS S+S S SS S S ESS SD+ D + + S+S S Sbjct: 1115 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDS 1174 Query: 739 EE-----DGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKT 793 + D + ++S S + SDSS SS S+ + S+ +S S ++ Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234 Query: 794 PPSSKSAPATKEISLLDLEDFTPPS 818 SS S+ ++ + D D + S Sbjct: 1235 SDSSDSSDSSDSSNSSDSSDSSDSS 1259 Score = 67.0 bits (162), Expect = 9e-11 Identities = 42/142 (29%), Positives = 64/142 (45%), Gaps = 2/142 (1%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S+DS S+S S SS S S SS SD+ D + + S+S S Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147 Query: 739 EE--DGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPS 796 E D + ++S S + SDSS+SS S+ + S+ +S S + S Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1207 Query: 797 SKSAPATKEISLLDLEDFTPPS 818 S S+ ++ D D + S Sbjct: 1208 SDSSDSSDSSDSSDSSDSSDSS 1229 Score = 66.6 bits (161), Expect = 1e-10 Identities = 48/169 (28%), Positives = 78/169 (46%), Gaps = 4/169 (2%) Query: 681 SEGESGPTESADSDP-ESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSE 739 S+ G ++S+DSD +S + SDS SS+S S +S+S SD++ D D S+S S Sbjct: 540 SDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSS 599 Query: 740 EDGKRKTKKKVPERKGEASSSDEGSDSS---SSSSESEMTSESEEEQLEPASWSRKTPPS 796 + + SSD SDSS S SS+S+ S+S + +S + + S Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659 Query: 797 SKSAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSLAADLEGLTLTDST 845 S S+ ++ D D + S S + S+ + E +DS+ Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708 Score = 66.6 bits (161), Expect = 1e-10 Identities = 44/141 (31%), Positives = 65/141 (46%), Gaps = 3/141 (2%) Query: 671 KEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKG 730 K K SDS S ++S+DS S+S+S S S+S +SS SD++ D Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603 Query: 731 RGSESEQSE-EDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASW 789 S+ S+ D + K K E+ SSD SDS S SS+S + S+ +S Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD--SDSKSDSSDSNSSDSSDNSDSSDSSN 661 Query: 790 SRKTPPSSKSAPATKEISLLD 810 S + SS S+ ++ S D Sbjct: 662 SSNSSDSSDSSDSSDSSSSSD 682 Score = 66.6 bits (161), Expect = 1e-10 Identities = 46/183 (25%), Positives = 77/183 (42%), Gaps = 2/183 (1%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQD 724 SN + SDS S ++S+DS S+S S SS S S +SS S++ D Sbjct: 963 SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS 1022 Query: 725 EDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSD--EGSDSSSSSSESEMTSESEEE 782 + S+S S + + ++SSD + SDSS SS S+ + S+ Sbjct: 1023 NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082 Query: 783 QLEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSLAADLEGLTLT 842 + +S S + SS S+ ++ D D + S S + S+ + + + Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 1142 Query: 843 DST 845 DS+ Sbjct: 1143 DSS 1145 Score = 65.9 bits (159), Expect = 2e-10 Identities = 41/154 (26%), Positives = 68/154 (44%), Gaps = 1/154 (0%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQD 724 SN S +S ++S+DS S+S S SS S S +SS+ SD+ D Sbjct: 951 SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1010 Query: 725 EDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQL 784 + + S+S S D + ++S S + SDSS SS+ S+ + S+ Sbjct: 1011 DSSDSSNSSDSSNS-SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1069 Query: 785 EPASWSRKTPPSSKSAPATKEISLLDLEDFTPPS 818 +S S + SS+S+ ++ + D D + S Sbjct: 1070 SDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103 Score = 65.5 bits (158), Expect = 3e-10 Identities = 46/182 (25%), Positives = 76/182 (41%), Gaps = 1/182 (0%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNED-Q 723 SN + SDS S ++S+DS S+S S SS S S +SS+ SD+ D Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS 948 Query: 724 DEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQ 783 D + S+ S + +S S + SDSS SS S+ ++ S+ Sbjct: 949 DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008 Query: 784 LEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSLAADLEGLTLTD 843 +S S + SS S+ ++ D D + S S + S++ + + +D Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068 Query: 844 ST 845 S+ Sbjct: 1069 SS 1070 Score = 65.1 bits (157), Expect = 3e-10 Identities = 41/135 (30%), Positives = 59/135 (43%), Gaps = 1/135 (0%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S+DS SES SDS SS+S S +SS S++ D D S + Sbjct: 681 SDSSNSSDSSDSSDSSNSSES-SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN 739 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 D + ++S S SDSS SS S+ + S +S S + SS Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799 Query: 799 SAPATKEISLLDLED 813 S+ ++ D D Sbjct: 800 SSDSSNSSDSSDSSD 814 Score = 65.1 bits (157), Expect = 3e-10 Identities = 38/125 (30%), Positives = 56/125 (44%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S DS S+S S SS S S +SS SD+ D D + S+ S Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 + + G S S SDSS+SS S+ + S +S S ++ SS Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893 Query: 799 SAPAT 803 S+ ++ Sbjct: 894 SSDSS 898 Score = 65.1 bits (157), Expect = 3e-10 Identities = 46/157 (29%), Positives = 69/157 (43%), Gaps = 1/157 (0%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S + S+DS S+S S SS+ S S +SS SD+ D + + S+S S Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS 1171 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 D + ++S S + SDSS SS S+ + S+ +S S + SS Sbjct: 1172 -SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1230 Query: 799 SAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSLAAD 835 S ++ D D + S S + STS + D Sbjct: 1231 SNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267 Score = 64.3 bits (155), Expect = 6e-10 Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 1/135 (0%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S + S+DS S+S S SS S S +SS SD+ + E + S+S+ S Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 + + + + SSD S+SS SS S+ ++ S+ +S S + SS Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSD-SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 772 Query: 799 SAPATKEISLLDLED 813 S+ ++ + D D Sbjct: 773 SSDSSDSSNSSDSND 787 Score = 64.3 bits (155), Expect = 6e-10 Identities = 39/127 (30%), Positives = 59/127 (46%), Gaps = 2/127 (1%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S + S+DS S+S S SS S S +SS SD+ D + S+S S Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105 Query: 739 EE--DGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPS 796 + D + ++S S + SDSS SS+ S+ + SE +S S + S Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165 Query: 797 SKSAPAT 803 S S+ ++ Sbjct: 1166 SDSSDSS 1172 Score = 63.2 bits (152), Expect = 1e-09 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 4/140 (2%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 S+S S ++S+DS S+S S SS S S +SS+ SD+ D + + S+S S Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1114 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 + ++S S + SDSS+SS S+ + S+ +S S + SS Sbjct: 1115 SDSSDSSNSSD----SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170 Query: 799 SAPATKEISLLDLEDFTPPS 818 S+ ++ + D D + S Sbjct: 1171 SSDSSDSSNSSDSSDSSDSS 1190 Score = 62.8 bits (151), Expect = 2e-09 Identities = 36/125 (28%), Positives = 60/125 (48%), Gaps = 1/125 (0%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S++S S+S SDS +SSES SS+SD+ D + + Sbjct: 672 SDSSDSSSSSDSSNSSDSSDS-SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 D + ++S+S + SDSS SS+ S+ + S+ +S S + SS Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN 790 Query: 799 SAPAT 803 S+ ++ Sbjct: 791 SSDSS 795 Score = 62.4 bits (150), Expect = 2e-09 Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 1/154 (0%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQD 724 SN + + SDS S + S SD +S + SDS SS S SS+S N Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755 Query: 725 EDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQL 784 D S D + ++S+S + SD SS+SS+S +S+S + Sbjct: 756 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD-SSNSSDSSNSSDSSDSSD 814 Query: 785 EPASWSRKTPPSSKSAPATKEISLLDLEDFTPPS 818 S S + SS S+ ++ + D D + S Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848 Score = 62.4 bits (150), Expect = 2e-09 Identities = 41/137 (29%), Positives = 64/137 (46%), Gaps = 2/137 (1%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQD 724 S+ + + SDS S ++S+DS S+ SDS SS+ S S SS SD+ D Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG-SDSDSSNRSDSSNSSDSSDSSDSS 874 Query: 725 EDEEKGRGSES-EQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQ 783 + S+S E S + ++S+S + SDSS+SS SE ++ S+ Sbjct: 875 NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934 Query: 784 LEPASWSRKTPPSSKSA 800 +S S + SS S+ Sbjct: 935 SSDSSNSSDSSDSSDSS 951 Score = 62.4 bits (150), Expect = 2e-09 Identities = 35/122 (28%), Positives = 57/122 (46%), Gaps = 1/122 (0%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S+DS S+S S S+ S S +SS S++ D D + S+ S Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918 Query: 739 -EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSS 797 D + ++S+S + SDSS SS+ S+ ++ S+ +S S + S Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978 Query: 798 KS 799 S Sbjct: 979 SS 980 Score = 62.4 bits (150), Expect = 2e-09 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 4/104 (3%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S + S+DS S+S S SS S S +SS SD+ D + + S+S S Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEE 782 + + ++S S SDSS SS S+ TS+S +E Sbjct: 1229 SDSNESSDSSD----SSDSSDSSNSSDSSDSSDSSDSTSDSNDE 1268 Score = 62.0 bits (149), Expect = 3e-09 Identities = 37/122 (30%), Positives = 54/122 (44%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S + S+DS S+S S SS+ S S +SS+ SD+ D + S+S S Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 + + SS S SS SS+S S+S+ +S S + SS Sbjct: 813 SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872 Query: 799 SA 800 S+ Sbjct: 873 SS 874 Score = 62.0 bits (149), Expect = 3e-09 Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 3/169 (1%) Query: 679 SDSEGESGPTESADSDPESESE--SDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESE 736 SDS S + S+DS S+S SDS S+ S S +SS+ SD+ D + + S+S Sbjct: 942 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001 Query: 737 QSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPS 796 S D + ++S+S + S+SS SS S+ + S+ +S S + S Sbjct: 1002 NS-SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060 Query: 797 SKSAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSLAADLEGLTLTDST 845 S S+ ++ D D + S S + S+ + + +DS+ Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109 Score = 61.6 bits (148), Expect = 4e-09 Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 4/139 (2%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQD 724 S + K + SDS+ +S + S+DS S+S S SS+ S S +SS SD+ Sbjct: 622 SKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSS 681 Query: 725 EDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQL 784 + S+S D ++ ++ SSD S+S+SS+S+ ++ S+ Sbjct: 682 DSSNSSDSSDS----SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737 Query: 785 EPASWSRKTPPSSKSAPAT 803 +S S + SS S+ ++ Sbjct: 738 SNSSDSSDSSDSSNSSDSS 756 Score = 61.6 bits (148), Expect = 4e-09 Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 2/141 (1%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQD 724 S+ + + + SDS S ++S++S S+S S SS S S +SS+ SD+ D Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693 Query: 725 EDEEKGRGSESEQSEEDGKRKTKKKVPERK--GEASSSDEGSDSSSSSSESEMTSESEEE 782 + S+S S + + ++S+S + SDSS+SS S+ + S Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753 Query: 783 QLEPASWSRKTPPSSKSAPAT 803 +S S + SS S+ ++ Sbjct: 754 DSSDSSDSSNSSDSSDSSDSS 774 Score = 61.2 bits (147), Expect = 5e-09 Identities = 37/123 (30%), Positives = 62/123 (50%), Gaps = 4/123 (3%) Query: 679 SDSEGESGPTESADSDPESESE--SDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESE 736 SDS S ++S+DS S+S SDS SS+S +SS+ SD+ + + + S+S Sbjct: 783 SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS 842 Query: 737 QSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPS 796 S + + ++S+S + SDSS SS+ S+ + S+ + +S S + S Sbjct: 843 DSSDSSDGSDSDS--SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900 Query: 797 SKS 799 S S Sbjct: 901 SDS 903 Score = 61.2 bits (147), Expect = 5e-09 Identities = 41/140 (29%), Positives = 65/140 (46%), Gaps = 7/140 (5%) Query: 679 SDSEGESGPTESADSDPESESESD-----SKSSSESGSGESSSESDNEDQDEDEEKGRGS 733 SDS S ++S+DS S+S+S S SS S S +SS+ SD+ D + E S Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892 Query: 734 ESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKT 793 +S S + ++S S SDSS SS+ S+ ++ S+ +S S + Sbjct: 893 DSSDSSNSSDSDSSDS--SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950 Query: 794 PPSSKSAPATKEISLLDLED 813 SS S+ ++ + D D Sbjct: 951 SNSSDSSNSSDSSNSSDSSD 970 Score = 60.8 bits (146), Expect = 7e-09 Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 1/139 (0%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQD 724 S+ + + SDS S ++S+DS S+S S+S S +SS+ SD+ D Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738 Query: 725 EDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQL 784 + S+S S D + ++S S + SDSS+SS ++ ++ S+ Sbjct: 739 NSSDSSDSSDSSNS-SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797 Query: 785 EPASWSRKTPPSSKSAPAT 803 +S S + SS S+ ++ Sbjct: 798 SNSSDSSNSSDSSDSSDSS 816 Score = 60.1 bits (144), Expect = 1e-08 Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 3/125 (2%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S+DS+ ES + SDS SS S +SS S++ D + SES S Sbjct: 871 SDSSNSSDSSDSSDSN-ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 ++ + + SS+ S SS+SS+S +S+S + +S S + SS Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSN--SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD 987 Query: 799 SAPAT 803 S+ ++ Sbjct: 988 SSDSS 992 Score = 59.7 bits (143), Expect = 1e-08 Identities = 37/122 (30%), Positives = 60/122 (49%), Gaps = 2/122 (1%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSE-SEQ 737 SDS S ++S++S S+S SDS S S S +SS+ SD+ D + S+ S+ Sbjct: 792 SDSSDSSNSSDSSNSSDSSDS-SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG 850 Query: 738 SEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSS 797 S+ D ++ ++S S SDSS SS +E ++ S+ +S S + S+ Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910 Query: 798 KS 799 S Sbjct: 911 SS 912 Score = 59.3 bits (142), Expect = 2e-08 Identities = 37/127 (29%), Positives = 64/127 (50%), Gaps = 4/127 (3%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S+DS S+S + S S+ S S +SS S++ D + S+S S Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS--S 816 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSS--SESEMTSESEEEQLEPASWSRKTPPS 796 + D + ++S+S + SDSS SS S+S+ ++ S+ +S S + S Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876 Query: 797 SKSAPAT 803 S S+ ++ Sbjct: 877 SDSSDSS 883 Score = 58.9 bits (141), Expect = 2e-08 Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 6/131 (4%) Query: 679 SDSEGESGPTESADSDPESESES-----DSKSSSESGSGESSSESDNEDQDEDEEKGRGS 733 SDS S ++S+DS S+S+S S SS S S +SS S++ D + S Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942 Query: 734 ESEQSEEDGKRKTKKKVPERKGEASSSD-EGSDSSSSSSESEMTSESEEEQLEPASWSRK 792 +S S + + + SSD SDSS SS+ S+ + S+ +S S Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002 Query: 793 TPPSSKSAPAT 803 + SS S+ ++ Sbjct: 1003 SSDSSDSSDSS 1013 Score = 58.5 bits (140), Expect = 3e-08 Identities = 45/155 (29%), Positives = 66/155 (42%), Gaps = 15/155 (9%) Query: 679 SDSEGESGPTESADSDPESE------SESDSKS-SSESGSGESSSESDNEDQDEDEEKGR 731 SDS S ++S+DS +S S+SDSKS SS+S S +SS SD+ D Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSD 667 Query: 732 GSESEQSEEDGKRKTKKKVPE--------RKGEASSSDEGSDSSSSSSESEMTSESEEEQ 783 S+S S + + E+S S + SDS SS S S S + Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727 Query: 784 LEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPS 818 +S S + SS S+ ++ + D D + S Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762 Score = 58.5 bits (140), Expect = 3e-08 Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 6/141 (4%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNED----QDEDEEKGRGSE 734 SDS S ++S+DS S S S SS S S +SS+ SD+ D D + Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDS 803 Query: 735 SEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSS--SSESEMTSESEEEQLEPASWSRK 792 S S+ + ++S+S + SDSS+S SS+S +S+ + S S Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN 863 Query: 793 TPPSSKSAPATKEISLLDLED 813 + SS S+ ++ D D Sbjct: 864 SSDSSDSSDSSNSSDSSDSSD 884 Score = 58.2 bits (139), Expect = 4e-08 Identities = 44/138 (31%), Positives = 67/138 (48%), Gaps = 7/138 (5%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESD---NEDQDEDEEKGRGSES 735 SDS S + S+DS S+S SDS SS+ S S SS SD + D + + GS+S Sbjct: 795 SDSSNSSDSSNSSDSSDSSDS-SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS 853 Query: 736 EQS-EEDGKRKTKKKVPERKGEASSSDEGSDS--SSSSSESEMTSESEEEQLEPASWSRK 792 + S D + +S S + SDS SS+SS+S +S S + +S S Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913 Query: 793 TPPSSKSAPATKEISLLD 810 + SS S+ +++ + D Sbjct: 914 SSDSSNSSDSSESSNSSD 931 Score = 58.2 bits (139), Expect = 4e-08 Identities = 41/150 (27%), Positives = 65/150 (43%), Gaps = 2/150 (1%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQD 724 S+ + + SDS S + S+DS S+S ++S +SS+S +SS+SD+ D Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS-NESSNSSDSSDSSNSSDSDSSDSS 909 Query: 725 EDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSS-SSESEMTSESEEEQ 783 + S S S E + + SSD S+SS SS S +S S + Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969 Query: 784 LEPASWSRKTPPSSKSAPATKEISLLDLED 813 +S S + SS S+ ++ D D Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999 Score = 57.8 bits (138), Expect = 6e-08 Identities = 32/115 (27%), Positives = 47/115 (40%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S+DS S+S S SS S S +SS SD+ D + E S+S S Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKT 793 + + S S++ SDS S S + E + + T Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298 Score = 56.2 bits (134), Expect = 2e-07 Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 4/138 (2%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESE--SDSKSSSESGSGESSSESDNED 722 SN + SDS S + S+DS S S SDS SS+ +SS+ SD+ + Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN 863 Query: 723 QDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEE 782 + + S S S + + ++SSD SDSS SS+ S+ + S Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSD--SDSSDSSNSSDSSDSSNSS 921 Query: 783 QLEPASWSRKTPPSSKSA 800 +S S SS S+ Sbjct: 922 DSSESSNSSDNSNSSDSS 939 Score = 56.2 bits (134), Expect = 2e-07 Identities = 30/100 (30%), Positives = 45/100 (45%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 SDS S ++S+DS S+S S SS + S +SS SD+ D + S+S S Sbjct: 1202 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDS 1261 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSE 778 D ++ + G + SD SDS S S + + Sbjct: 1262 TSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301 Score = 55.8 bits (133), Expect = 2e-07 Identities = 43/148 (29%), Positives = 67/148 (45%), Gaps = 28/148 (18%) Query: 681 SEGESGPTESADSDPESESESDSKSSSES-GSGESSSESDNE---------DQDEDEEKG 730 S+ S +S D D +S D SS ES G+ +++SESDN + DE ++ G Sbjct: 443 SDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNG 502 Query: 731 RGSESEQSEEDGKRKTKK------------------KVPERKGEASSSDEGSDSSSSSSE 772 GS+S+ +E+D T K KG++ SSD S SS+SS+ Sbjct: 503 NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562 Query: 773 SEMTSESEEEQLEPASWSRKTPPSSKSA 800 S +S+S+ +S S + S + Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDS 590 Score = 55.5 bits (132), Expect = 3e-07 Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 2/136 (1%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 S+S S ++S+DS S S + SS+ S S +SS+ SD+ + + + S+S+ S Sbjct: 762 SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821 Query: 739 -EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSS 797 D + ++S S + SD S S S + S + + + +S S + SS Sbjct: 822 NSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD-SSDSSNSSDSS 880 Query: 798 KSAPATKEISLLDLED 813 S+ + + + D D Sbjct: 881 DSSDSNESSNSSDSSD 896 Score = 55.1 bits (131), Expect = 4e-07 Identities = 32/138 (23%), Positives = 61/138 (44%), Gaps = 4/138 (2%) Query: 666 NREKRKEKEKPFYSDSEGESGPTESAD----SDPESESESDSKSSSESGSGESSSESDNE 721 N + E + S + ES D SD + + DS S+S++ + +S+ +N Sbjct: 474 NDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNG 533 Query: 722 DQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEE 781 + D D+ +S+ S+ D + ++ SSD S S S SS+S+ + S+ Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS 593 Query: 782 EQLEPASWSRKTPPSSKS 799 + + ++ S + S S Sbjct: 594 DSSDSSNSSDSSDSSDSS 611 Score = 54.7 bits (130), Expect = 5e-07 Identities = 35/135 (25%), Positives = 62/135 (45%), Gaps = 4/135 (2%) Query: 680 DSEGESGPTESADSDPESESESDSKSSSESGSGES-SSESDNEDQDEDEEKGRGSESEQS 738 D + T ++DS+ + +D S+SG G+S SS+SD+ D + S+S+ S Sbjct: 513 DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS 572 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 + + + + + SSD S SS+SS+S +S+S + S K+ S Sbjct: 573 DSNSSSDSDSSDSD---SSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS 629 Query: 799 SAPATKEISLLDLED 813 + ++ S D D Sbjct: 630 ESDSSDSDSKSDSSD 644 Score = 54.7 bits (130), Expect = 5e-07 Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 3/138 (2%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESS--SESDNEDQDEDEEKGRGSESE 736 S +S + S+DS S+S S SS S S +SS S+SD+ ++ + S+S Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871 Query: 737 QSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSE-SEEEQLEPASWSRKTPP 795 S E + SSD + S S SS+S +S+ S+ +S S + Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931 Query: 796 SSKSAPATKEISLLDLED 813 +S S+ ++ D D Sbjct: 932 NSNSSDSSNSSDSSDSSD 949 Score = 54.7 bits (130), Expect = 5e-07 Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 8/102 (7%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSES--- 735 SDS S ++S+DS S+S S SS S S ESS SD+ D + S+S Sbjct: 1199 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDS 1258 Query: 736 ----EQSEEDGKRKTKKKVPERKGEASSSD-EGSDSSSSSSE 772 S ++ ++K G S SD EGSDS+ S+S+ Sbjct: 1259 SDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300 Score = 53.9 bits (128), Expect = 8e-07 Identities = 34/125 (27%), Positives = 64/125 (51%), Gaps = 5/125 (4%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 S G ++ A+ D +S+S SD+ +S +G+G + ++ DN+ D + K S+S+ S Sbjct: 498 SKDNGNGSDSKGAEDD-DSDSTSDTNNSDSNGNGNNGND-DNDKSDSGKGKSDSSDSDSS 555 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 + + ++S S+ SDS SS S+S +S+S+ +S S + SS Sbjct: 556 DSSNSSDSS---DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD 612 Query: 799 SAPAT 803 S+ ++ Sbjct: 613 SSDSS 617 Score = 53.1 bits (126), Expect = 1e-06 Identities = 28/92 (30%), Positives = 42/92 (45%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 S+S S ++S+DS S+S S SS S S +SS SD+ D + + +ES S Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSS 770 + + + SSD SDS+ S Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269 Score = 52.4 bits (124), Expect = 2e-06 Identities = 30/132 (22%), Positives = 59/132 (44%), Gaps = 3/132 (2%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGE---SSSESDNEDQDEDEEKGRGSES 735 ++SE ++ + D+ S+ D+ + S+S E S S SD + D + G++ Sbjct: 477 ANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDD 536 Query: 736 EQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPP 795 + GK K+ + ++SSD S S SS+S +S+S+ + + S Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596 Query: 796 SSKSAPATKEIS 807 S ++ + + S Sbjct: 597 DSSNSSDSSDSS 608 Score = 37.7 bits (86), Expect = 0.059 Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 21/144 (14%) Query: 683 GESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQ----- 737 G + D E E + K SS + G+ + ED D D G+ S+S++ Sbjct: 250 GADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKED-DHDSSIGQNSDSKEYYDPE 308 Query: 738 ------SEEDGKRKTKKK-----VPERKGEASSSD--EGSDSSSSSSESEMTSESEEEQL 784 +E DG + +K + +PE G D + + S E+ +T ESE + Sbjct: 309 GKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAV 368 Query: 785 EPA--SWSRKTPPSSKSAPATKEI 806 + PSS + TKE+ Sbjct: 369 GKSQDKGIEIKGPSSGNRNITKEV 392 Score = 35.8 bits (81), Expect = 0.22 Identities = 26/133 (19%), Positives = 54/133 (40%), Gaps = 4/133 (3%) Query: 684 ESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGK 743 E P ++ + E+E + ++G S DEDE++G G + ++ +GK Sbjct: 212 EITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGK 271 Query: 744 RKTKKKVPERKGEASSSDEGSDSS---SSSSESEMTSESEEEQLEPASWSRKTPPSSKSA 800 + ++G+ ++ DSS +S S+ E +E+ + + SA Sbjct: 272 DSSNNS-KGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSA 330 Query: 801 PATKEISLLDLED 813 ++ +ED Sbjct: 331 GIPEDNGSQRIED 343 Score = 33.9 bits (76), Expect = 0.85 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%) Query: 678 YSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQ 737 Y D EG+ P D D S+SE +S E +G E + + ++ +++ Sbjct: 304 YYDPEGKEDPHNEVDGDKTSKSEENSAGIPED-NGSQRIEDTQKLNHRESKRVENRITKE 362 Query: 738 SEEDGKRKTKKKVPERKGEASSS 760 SE K++ K E KG +S + Sbjct: 363 SETHAVGKSQDKGIEIKGPSSGN 385 >gi|221316632 coatomer protein complex, subunit beta 1 [Homo sapiens] Length = 953 Score = 68.6 bits (166), Expect = 3e-11 Identities = 100/549 (18%), Positives = 209/549 (38%), Gaps = 86/549 (15%) Query: 42 LKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVA-CKNIEVKKLVYVYLVRY 100 LK L+ K EA+K+++ MI G+ L +++ V ++ +KKL+ V+ Sbjct: 26 LKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIV 85 Query: 101 AEEQQDLALLS-----ISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAAS 155 + D LL +++ L+ PN+ IR S LR L ++ ++ +M AI+ Sbjct: 86 PKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLE 145 Query: 156 DMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPER-- 213 YVR+ A AI +Y E L+ D L+ +V + C Sbjct: 146 HRHSYVRRNAVLAIYTIY-----------RNFEHLIPDAPELIHDFLVNEKDASCKRNAF 194 Query: 214 IDLIHKNYRK----LCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENAEKAF 269 + LIH + + L + V+ +G ++ + ++ + +P++ + + Sbjct: 195 MMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFI-----RCI 249 Query: 270 YGSEEDEAKGAGSEETAAAAAPSRKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYF 329 Y + + E S P + A AQ Y Sbjct: 250 YNLLQSSSPAVKYEAAGTLVTLSSAP-----------------------TAIKAAAQCYI 286 Query: 330 HLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFY-----IRS 384 L K S + V+ +VL + + +K E L+ + S Sbjct: 287 DLIIK--------------ESDNNVKLIVLDRL--IELKEHPAHERVLQDLVMDILRVLS 330 Query: 385 TDPTQIKILKLEVLTNLANETNIPTVLREFQTYI---------RSMDKDFVAATIQAIGR 435 T +++ L++ +L + N+ ++ + + DK + ++ + Sbjct: 331 TPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDK-YRQLLVRTLHS 389 Query: 436 CATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNI 495 C+ + + L++ LS+ +E A+ + +++ +Q I++ + ++ I Sbjct: 390 CSVRFPDMAANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAI 449 Query: 496 QVPMARASILWLIGEYC---EHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTN 552 + LW++GEYC E + + ++ R + + E +I K + L + +T Sbjct: 450 KSVKIYRGALWILGEYCSTKEDIQSVMTEIRRSLGEIPIVESEI-KKEAGELKPEEEITV 508 Query: 553 SKQTKLLTQ 561 KL+T+ Sbjct: 509 GPVQKLVTE 517 >gi|221316630 coatomer protein complex, subunit beta 1 [Homo sapiens] Length = 953 Score = 68.6 bits (166), Expect = 3e-11 Identities = 100/549 (18%), Positives = 209/549 (38%), Gaps = 86/549 (15%) Query: 42 LKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVA-CKNIEVKKLVYVYLVRY 100 LK L+ K EA+K+++ MI G+ L +++ V ++ +KKL+ V+ Sbjct: 26 LKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIV 85 Query: 101 AEEQQDLALLS-----ISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAAS 155 + D LL +++ L+ PN+ IR S LR L ++ ++ +M AI+ Sbjct: 86 PKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLE 145 Query: 156 DMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPER-- 213 YVR+ A AI +Y E L+ D L+ +V + C Sbjct: 146 HRHSYVRRNAVLAIYTIY-----------RNFEHLIPDAPELIHDFLVNEKDASCKRNAF 194 Query: 214 IDLIHKNYRK----LCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENAEKAF 269 + LIH + + L + V+ +G ++ + ++ + +P++ + + Sbjct: 195 MMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFI-----RCI 249 Query: 270 YGSEEDEAKGAGSEETAAAAAPSRKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYF 329 Y + + E S P + A AQ Y Sbjct: 250 YNLLQSSSPAVKYEAAGTLVTLSSAP-----------------------TAIKAAAQCYI 286 Query: 330 HLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFY-----IRS 384 L K S + V+ +VL + + +K E L+ + S Sbjct: 287 DLIIK--------------ESDNNVKLIVLDRL--IELKEHPAHERVLQDLVMDILRVLS 330 Query: 385 TDPTQIKILKLEVLTNLANETNIPTVLREFQTYI---------RSMDKDFVAATIQAIGR 435 T +++ L++ +L + N+ ++ + + DK + ++ + Sbjct: 331 TPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDK-YRQLLVRTLHS 389 Query: 436 CATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNI 495 C+ + + L++ LS+ +E A+ + +++ +Q I++ + ++ I Sbjct: 390 CSVRFPDMAANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAI 449 Query: 496 QVPMARASILWLIGEYC---EHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTN 552 + LW++GEYC E + + ++ R + + E +I K + L + +T Sbjct: 450 KSVKIYRGALWILGEYCSTKEDIQSVMTEIRRSLGEIPIVESEI-KKEAGELKPEEEITV 508 Query: 553 SKQTKLLTQ 561 KL+T+ Sbjct: 509 GPVQKLVTE 517 >gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens] Length = 953 Score = 68.6 bits (166), Expect = 3e-11 Identities = 100/549 (18%), Positives = 209/549 (38%), Gaps = 86/549 (15%) Query: 42 LKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVA-CKNIEVKKLVYVYLVRY 100 LK L+ K EA+K+++ MI G+ L +++ V ++ +KKL+ V+ Sbjct: 26 LKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIV 85 Query: 101 AEEQQDLALLS-----ISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAAS 155 + D LL +++ L+ PN+ IR S LR L ++ ++ +M AI+ Sbjct: 86 PKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLE 145 Query: 156 DMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPER-- 213 YVR+ A AI +Y E L+ D L+ +V + C Sbjct: 146 HRHSYVRRNAVLAIYTIY-----------RNFEHLIPDAPELIHDFLVNEKDASCKRNAF 194 Query: 214 IDLIHKNYRK----LCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENAEKAF 269 + LIH + + L + V+ +G ++ + ++ + +P++ + + Sbjct: 195 MMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFI-----RCI 249 Query: 270 YGSEEDEAKGAGSEETAAAAAPSRKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYF 329 Y + + E S P + A AQ Y Sbjct: 250 YNLLQSSSPAVKYEAAGTLVTLSSAP-----------------------TAIKAAAQCYI 286 Query: 330 HLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFY-----IRS 384 L K S + V+ +VL + + +K E L+ + S Sbjct: 287 DLIIK--------------ESDNNVKLIVLDRL--IELKEHPAHERVLQDLVMDILRVLS 330 Query: 385 TDPTQIKILKLEVLTNLANETNIPTVLREFQTYI---------RSMDKDFVAATIQAIGR 435 T +++ L++ +L + N+ ++ + + DK + ++ + Sbjct: 331 TPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDK-YRQLLVRTLHS 389 Query: 436 CATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNI 495 C+ + + L++ LS+ +E A+ + +++ +Q I++ + ++ I Sbjct: 390 CSVRFPDMAANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAI 449 Query: 496 QVPMARASILWLIGEYC---EHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTN 552 + LW++GEYC E + + ++ R + + E +I K + L + +T Sbjct: 450 KSVKIYRGALWILGEYCSTKEDIQSVMTEIRRSLGEIPIVESEI-KKEAGELKPEEEITV 508 Query: 553 SKQTKLLTQ 561 KL+T+ Sbjct: 509 GPVQKLVTE 517 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 67.8 bits (164), Expect = 5e-11 Identities = 41/147 (27%), Positives = 64/147 (43%), Gaps = 2/147 (1%) Query: 670 RKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDE--DE 727 R+ +P DS GE ES + ES E + E + +SD+ D+ E DE Sbjct: 1020 RRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDE 1079 Query: 728 EKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPA 787 + SE+ E D + + K EA+SS E S+SS S SE + S E++ E Sbjct: 1080 DTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVV 1139 Query: 788 SWSRKTPPSSKSAPATKEISLLDLEDF 814 + + + A + ++ EDF Sbjct: 1140 AREEEEEEEEEEMVAEESMASAGPEDF 1166 Score = 54.3 bits (129), Expect = 6e-07 Identities = 45/196 (22%), Positives = 76/196 (38%), Gaps = 34/196 (17%) Query: 654 RNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGE 713 R +E+ + +E E+++ + E E E D D +S+ +S++ E + Sbjct: 1025 RPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALS 1084 Query: 714 SSSESDNEDQDEDE------EKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSS 767 +SE D D DE+E K + S +S E E SS E S SS Sbjct: 1085 EASEKDEGDSDEEETVSIVTSKAEATSSSESSE-------------SSEFESSSESSPSS 1131 Query: 768 SSSSESEMTSESEEEQLEPASWSRKTPPS---------------SKSAPATKEISLLDLE 812 S E + E EEE+ E + ++ S + APA + + + Sbjct: 1132 SEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEV 1191 Query: 813 DFTPPSVQPVSPPAIV 828 D +V P P+++ Sbjct: 1192 DIETEAVAPEERPSML 1207 Score = 41.6 bits (96), Expect = 0.004 Identities = 47/182 (25%), Positives = 76/182 (41%), Gaps = 24/182 (13%) Query: 639 QELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESE 698 QE + EEA + E E + + R E E + E+ + DSD E Sbjct: 1045 QESTEEEEEAEEE-----EEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEET 1099 Query: 699 -----SESDSKSSSESGSG---ESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKV 750 S++++ SSSES ESSSES + EDEE+ E E+ EE+ + ++ + Sbjct: 1100 VSIVTSKAEATSSSESSESSEFESSSES-SPSSSEDEEEVVAREEEEEEEEEEMVAEESM 1158 Query: 751 P-------ERKGEASSSDEGS---DSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSA 800 E+ GE ++ G+ DS E ++ +E+ + P+ P Sbjct: 1159 ASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEE 1218 Query: 801 PA 802 PA Sbjct: 1219 PA 1220 Score = 40.0 bits (92), Expect = 0.012 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 3/87 (3%) Query: 702 DSKSSSESGSGESSSESDNEDQDEDEEKGRG---SESEQSEEDGKRKTKKKVPERKGEAS 758 D+ SS + S+ D ED++ + E+ R + E ++ D K ++ P R E Sbjct: 971 DTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELD 1030 Query: 759 SSDEGSDSSSSSSESEMTSESEEEQLE 785 S E + S S E E T E EE + E Sbjct: 1031 SGGEEDEKESLSEEQESTEEEEEAEEE 1057 Score = 30.8 bits (68), Expect = 7.2 Identities = 43/202 (21%), Positives = 68/202 (33%), Gaps = 18/202 (8%) Query: 642 PDWPEEAPDPSVRNVEVPEWTKC-------SNREKRKEKEKPFYSDSEGESGPTESADSD 694 P+ P ++ D + + + TK S+ E + E S S+ +S Sbjct: 492 PEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQ 551 Query: 695 PESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGK-------RKTK 747 P + S S E S + D DEDEE G E G +T Sbjct: 552 PGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTA 611 Query: 748 KKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPP----SSKSAPAT 803 + + G+ + + E D SS +M +E P + + P +A A Sbjct: 612 EVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAA 671 Query: 804 KEISLLDLEDFTPPSVQPVSPP 825 + L PP P+ PP Sbjct: 672 PSVLAPTLPLPPPPGFPPLPPP 693 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 66.6 bits (161), Expect = 1e-10 Identities = 60/205 (29%), Positives = 93/205 (45%), Gaps = 38/205 (18%) Query: 644 WPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDS 703 W P P E+ + K EK +E++ SD + S+S+ Sbjct: 219 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLL----------------SDLQDISDSER 262 Query: 704 KSSS-ESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDE 762 K+SS ES S ES S S+ E+++E+EE+ GS SE+SEE+ + + + E + S+S+E Sbjct: 263 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE----EEEETGSNSEE 318 Query: 763 GSDSSSSSSESEMTSESEEEQLE----PASWSRKTPPSSKSAPATKEI-------SLLDL 811 S+ S+ E SE EE + E SR S +S A +E+ S L Sbjct: 319 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 378 Query: 812 EDFTPPSVQPVSPPAIVSTSLAADL 836 D+ P S PA++ L +L Sbjct: 379 GDYVPDS------PALLPIELKQEL 397 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 66.6 bits (161), Expect = 1e-10 Identities = 60/205 (29%), Positives = 93/205 (45%), Gaps = 38/205 (18%) Query: 644 WPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDS 703 W P P E+ + K EK +E++ SD + S+S+ Sbjct: 229 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLL----------------SDLQDISDSER 272 Query: 704 KSSS-ESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDE 762 K+SS ES S ES S S+ E+++E+EE+ GS SE+SEE+ + + + E + S+S+E Sbjct: 273 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE----EEEETGSNSEE 328 Query: 763 GSDSSSSSSESEMTSESEEEQLE----PASWSRKTPPSSKSAPATKEI-------SLLDL 811 S+ S+ E SE EE + E SR S +S A +E+ S L Sbjct: 329 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 388 Query: 812 EDFTPPSVQPVSPPAIVSTSLAADL 836 D+ P S PA++ L +L Sbjct: 389 GDYVPDS------PALLPIELKQEL 407 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 66.6 bits (161), Expect = 1e-10 Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 34/193 (17%) Query: 644 WPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDS 703 W P P E+ + K EK +E++ SD + S+S+ Sbjct: 220 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLL----------------SDLQDISDSER 263 Query: 704 KSSS-ESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDE 762 K+SS ES S ES S S+ E+++E+EE+ GS SE+SEE+ + + + E + S+S+E Sbjct: 264 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE----EEEETGSNSEE 319 Query: 763 GSDSSSSSSESEMTSESEEEQLE----PASWSRKTPPSSKSAPATKEI-------SLLDL 811 S+ S+ E SE EE + E SR S +S A +E+ S L Sbjct: 320 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 379 Query: 812 EDFTP--PSVQPV 822 D+ P P++ P+ Sbjct: 380 GDYVPDSPALSPI 392 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 66.6 bits (161), Expect = 1e-10 Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 34/193 (17%) Query: 644 WPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDS 703 W P P E+ + K EK +E++ SD + S+S+ Sbjct: 229 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLL----------------SDLQDISDSER 272 Query: 704 KSSS-ESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDE 762 K+SS ES S ES S S+ E+++E+EE+ GS SE+SEE+ + + + E + S+S+E Sbjct: 273 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE----EEEETGSNSEE 328 Query: 763 GSDSSSSSSESEMTSESEEEQLE----PASWSRKTPPSSKSAPATKEI-------SLLDL 811 S+ S+ E SE EE + E SR S +S A +E+ S L Sbjct: 329 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 388 Query: 812 EDFTP--PSVQPV 822 D+ P P++ P+ Sbjct: 389 GDYVPDSPALSPI 401 Score = 34.3 bits (77), Expect = 0.65 Identities = 41/207 (19%), Positives = 70/207 (33%), Gaps = 47/207 (22%) Query: 660 EWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESD 719 EW R+KR+E + G G D + E + + + E + + Sbjct: 136 EW----ERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKE 191 Query: 720 NEDQDEDEEKGRGSESEQSEE--------------------------------DGKRKTK 747 E + E+ K R + E S DG++ K Sbjct: 192 RERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVK 251 Query: 748 KKVPERK-----------GEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPS 796 ++ E + E +S S S+ S S SE E EEE+ E S S ++ Sbjct: 252 EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE 311 Query: 797 SKSAPATKEISLLDLEDFTPPSVQPVS 823 + +E + + E+ + S + VS Sbjct: 312 EEEEEEEEEETGSNSEEASEQSAEEVS 338 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 66.6 bits (161), Expect = 1e-10 Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 34/193 (17%) Query: 644 WPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDS 703 W P P E+ + K EK +E++ SD + S+S+ Sbjct: 197 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLL----------------SDLQDISDSER 240 Query: 704 KSSS-ESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDE 762 K+SS ES S ES S S+ E+++E+EE+ GS SE+SEE+ + + + E + S+S+E Sbjct: 241 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE----EEEETGSNSEE 296 Query: 763 GSDSSSSSSESEMTSESEEEQLE----PASWSRKTPPSSKSAPATKEI-------SLLDL 811 S+ S+ E SE EE + E SR S +S A +E+ S L Sbjct: 297 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 356 Query: 812 EDFTP--PSVQPV 822 D+ P P++ P+ Sbjct: 357 GDYVPDSPALSPI 369 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 66.6 bits (161), Expect = 1e-10 Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 34/193 (17%) Query: 644 WPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDS 703 W P P E+ + K EK +E++ SD + S+S+ Sbjct: 186 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLL----------------SDLQDISDSER 229 Query: 704 KSSS-ESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDE 762 K+SS ES S ES S S+ E+++E+EE+ GS SE+SEE+ + + + E + S+S+E Sbjct: 230 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE----EEEETGSNSEE 285 Query: 763 GSDSSSSSSESEMTSESEEEQLE----PASWSRKTPPSSKSAPATKEI-------SLLDL 811 S+ S+ E SE EE + E SR S +S A +E+ S L Sbjct: 286 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 345 Query: 812 EDFTP--PSVQPV 822 D+ P P++ P+ Sbjct: 346 GDYVPDSPALSPI 358 >gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2 [Homo sapiens] Length = 782 Score = 66.6 bits (161), Expect = 1e-10 Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 34/193 (17%) Query: 644 WPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDS 703 W P P E+ + K EK +E++ SD + S+S+ Sbjct: 231 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLL----------------SDLQDISDSER 274 Query: 704 KSSS-ESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDE 762 K+SS ES S ES S S+ E+++E+EE+ GS SE+SEE+ + + + E + S+S+E Sbjct: 275 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE----EEEETGSNSEE 330 Query: 763 GSDSSSSSSESEMTSESEEEQLE----PASWSRKTPPSSKSAPATKEI-------SLLDL 811 S+ S+ E SE EE + E SR S +S A +E+ S L Sbjct: 331 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 390 Query: 812 EDFTP--PSVQPV 822 D+ P P++ P+ Sbjct: 391 GDYVPDSPALSPI 403 >gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform 3 [Homo sapiens] Length = 526 Score = 64.3 bits (155), Expect = 6e-10 Identities = 49/144 (34%), Positives = 77/144 (53%), Gaps = 18/144 (12%) Query: 693 SDPESESESDSKSSS-ESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVP 751 SD + S+S+ K+SS ES S ES S S+ E+++E+EE+ GS SE+SEE+ + + + Sbjct: 8 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE---- 63 Query: 752 ERKGEASSSDEGSDSSSSSSESEMTSESEEEQLE----PASWSRKTPPSSKSAPATKEI- 806 E + S+S+E S+ S+ E SE EE + E SR S +S A +E+ Sbjct: 64 EEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVG 123 Query: 807 ------SLLDLEDFTP--PSVQPV 822 S L D+ P P++ P+ Sbjct: 124 EGTPQSSALTEGDYVPDSPALSPI 147 Score = 49.7 bits (117), Expect = 2e-05 Identities = 43/160 (26%), Positives = 74/160 (46%), Gaps = 28/160 (17%) Query: 679 SDSEGESGPTESADSDP----ESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSE 734 SDSE ++ ES+ ++ E E E + + E + E S E + E+++E+EE G SE Sbjct: 14 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 73 Query: 735 --SEQS---------EEDGKRKTKKK---VPERK-----GEASSSDE--GSDSSSSSSES 773 SEQS ED +R+ + VPE + GE+ ++E G + SS+ + Sbjct: 74 EASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALT 133 Query: 774 EMTSESEEEQLEPASWSRKTP---PSSKSAPATKEISLLD 810 E + L P ++ P P+ + + +E L+ Sbjct: 134 EGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLN 173 Score = 45.1 bits (105), Expect = 4e-04 Identities = 33/130 (25%), Positives = 62/130 (47%), Gaps = 11/130 (8%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQD 724 S E+ +E+E+ + EG + + + E E E ++ S+SE S +S+ E E+ Sbjct: 34 SEEEEEEEEEE----EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 89 Query: 725 EDEEKGRGS------ESEQSEEDGK-RKTKKKVPERKGEASSSDEGSDSSSSSSESEMTS 777 EDEE+ + ES + G+ + +++V E ++S+ EG S + S + Sbjct: 90 EDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIEL 149 Query: 778 ESEEEQLEPA 787 + E + PA Sbjct: 150 KQELPKYLPA 159 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 63.9 bits (154), Expect = 8e-10 Identities = 50/184 (27%), Positives = 75/184 (40%), Gaps = 9/184 (4%) Query: 661 WTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDN 720 W K ++ + +E + G + A ++ + ES+S SSS SGS SSS S + Sbjct: 2517 WPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSS 2576 Query: 721 --------EDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSE 772 E+ D++ + G G+ R +SSS S SSSSSS Sbjct: 2577 SGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSS 2636 Query: 773 SEMTSESEEEQLEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSL 832 S +S S +S S + SS S+ ++ S D ED + S +P S Sbjct: 2637 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD-EDSSCSSDDEAAPAPTAGPSA 2695 Query: 833 AADL 836 A L Sbjct: 2696 QAAL 2699 Score = 54.7 bits (130), Expect = 5e-07 Identities = 42/182 (23%), Positives = 68/182 (37%), Gaps = 21/182 (11%) Query: 665 SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSG------------ 712 + ++ +E E S S S + S+ S E+E E + + + G G Sbjct: 2549 AEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSR 2608 Query: 713 -----ESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSS 767 SSS S + S S S + +SSS S SS Sbjct: 2609 AASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668 Query: 768 SSSSESEMTSESEEEQLEPASWSRKTPPSSKSAPATKEISLLDLEDFTP----PSVQPVS 823 SSS+ E +S S +++ PA + + ++ ATK+ +P P+ QP + Sbjct: 2669 SSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQA 2728 Query: 824 PP 825 PP Sbjct: 2729 PP 2730 Score = 45.4 bits (106), Expect = 3e-04 Identities = 34/148 (22%), Positives = 53/148 (35%), Gaps = 13/148 (8%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738 S + + + S+ S S S S S SSS S S SSS S + S S S Sbjct: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666 Query: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSK 798 + EA+ + S+ ++ ++ T ++ + + S +KTP Sbjct: 2667 SSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQP 2726 Query: 799 SAPATKEISLLDLEDFTPPSVQPVSPPA 826 AP P QP+ P A Sbjct: 2727 QAP-------------PPQPTQPLQPKA 2741 Score = 43.5 bits (101), Expect = 0.001 Identities = 33/153 (21%), Positives = 56/153 (36%), Gaps = 4/153 (2%) Query: 659 PEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSES 718 P + S+ S S S + S+ S S S S S SSS S S SSS S Sbjct: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671 Query: 719 DNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSE 778 ++ + + + + K ++ G+A S + + + + Sbjct: 2672 TTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPP 2731 Query: 779 SEEEQLEP-ASWSRKTPPSSKSA---PATKEIS 807 + L+P A K+ P + P TKE++ Sbjct: 2732 QPTQPLQPKAQAGAKSRPKKREGVHLPTTKELA 2764 Score = 31.2 bits (69), Expect = 5.5 Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 19/149 (12%) Query: 671 KEKEKPFYSDSEGESGPTESADS--------DPESESES-DSKSSSESGSGESSSESDNE 721 K K+K SD E + + A S P S+S KS + G G + D+ Sbjct: 1613 KIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDSAGGKSKTSGGCGRYLTPYDSL 1672 Query: 722 DQDEDEEKGRG-SESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSS-------SES 773 + +G S +S +GK K K RK E G S+ S S S Sbjct: 1673 LGKNRKALAKGLGLSLKSSREGKHKRAAKT--RKMEVGFKARGQPKSAHSPFASEVSSYS 1730 Query: 774 EMTSESEEEQLEPASWSRKTPPSSKSAPA 802 T E+E+ W + P SSK P+ Sbjct: 1731 YNTDSEEDEEFLKDEWPAQGPSSSKLTPS 1759 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 61.2 bits (147), Expect = 5e-09 Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 5/119 (4%) Query: 671 KEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKG 730 +E+E + EGE G E + + E E E + + E G G+ E + + + +EE+G Sbjct: 879 EEEEGEGEGEEEGE-GEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG 937 Query: 731 RGS----ESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLE 785 G E E EE+G+ + +++ E +GE EG + E E E EEE+ E Sbjct: 938 EGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996 Score = 58.5 bits (140), Expect = 3e-08 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 3/106 (2%) Query: 680 DSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSE 739 + E E G E + + E E E + + E G GE E + +E+E + G E + E Sbjct: 947 EGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGE 1006 Query: 740 EDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLE 785 E+G+ + ++ E +GE EG + E E E EE + E Sbjct: 1007 EEGEGEGEE---EEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKE 1049 Score = 57.0 bits (136), Expect = 9e-08 Identities = 36/120 (30%), Positives = 54/120 (45%), Gaps = 5/120 (4%) Query: 663 KCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNED 722 K R ++EK + EGE TE + E E + E G GE E + + Sbjct: 776 KKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEG-GEVEEGKGEREEEEEEGE 834 Query: 723 QDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEE 782 +E+E +G E E EE+G+ K +++ E +GE +EG + E E E EEE Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGE----EEGEEGEGEGEEEEGEGEGEEE 890 Score = 57.0 bits (136), Expect = 9e-08 Identities = 36/125 (28%), Positives = 58/125 (46%), Gaps = 9/125 (7%) Query: 668 EKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSES------DNE 721 E+ +E+E+ + EGE G E + + E E E + E G GE E + E Sbjct: 825 EREEEEEEGEGEEEEGE-GEEEEGEGE-EEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882 Query: 722 DQDEDEEKGRG-SESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESE 780 + E EE+G G E E+ E +G+ + + + E +GE +EG + E E E E Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE 942 Query: 781 EEQLE 785 + + E Sbjct: 943 DGEGE 947 Score = 55.8 bits (133), Expect = 2e-07 Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 7/118 (5%) Query: 671 KEKEKPFYSDSEGESGP--TESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEE 728 +E+E + EGE G E + + E E E E G GE E E + E EE Sbjct: 850 EEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE---EGEGEGEE 906 Query: 729 KGRGSESEQSEEDGKRKTKKKVPERKGEASSSD-EGSDSSSSSSESEMTSESEEEQLE 785 +G G E E+ E +GK + + + E +GE + EG D E E E EEE+ E Sbjct: 907 EGEG-EGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE 963 Score = 55.5 bits (132), Expect = 3e-07 Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 9/133 (6%) Query: 657 EVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDS--KSSSESGSGES 714 E EW E+ E E + EGE G E + + E E E + + E G GE Sbjct: 951 EEGEW---EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007 Query: 715 SSESDNEDQD----EDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSS 770 E + E+++ E E +G E E EE+G+ + +++ E +GE + + + Sbjct: 1008 EGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEG 1067 Query: 771 SESEMTSESEEEQ 783 E E E Q Sbjct: 1068 KYQETGEEENERQ 1080 Score = 55.1 bits (131), Expect = 4e-07 Identities = 37/152 (24%), Positives = 59/152 (38%), Gaps = 3/152 (1%) Query: 637 GYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPE 696 G +E E + R E E + E + K + + EGE E + E Sbjct: 787 GEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEE 846 Query: 697 ---SESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPER 753 E E + K E GE E + + + +EE+G G E+ E +G+ + + E Sbjct: 847 GEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEE 906 Query: 754 KGEASSSDEGSDSSSSSSESEMTSESEEEQLE 785 +GE +E + E E EEE+ E Sbjct: 907 EGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938 Score = 55.1 bits (131), Expect = 4e-07 Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 6/120 (5%) Query: 671 KEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGE---SSSESDNEDQDEDE 727 +E+E + EGE G E + + E E E D + E GE E + E ++E E Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGE-DGEGEGEEEEGEWEGEEEEGEGEGEEEGE 971 Query: 728 EKGRGSESEQSEEDGKRKTKKKVPERKG--EASSSDEGSDSSSSSSESEMTSESEEEQLE 785 +G E E EE+G+ + +++ E +G E +EG E E+ E E E+ E Sbjct: 972 GEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE 1031 Score = 52.0 bits (123), Expect = 3e-06 Identities = 40/158 (25%), Positives = 62/158 (39%), Gaps = 29/158 (18%) Query: 657 EVPEWTKCSNREK---------RKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSS 707 E EW K E+ +KE+ + E E G E + D E E E + + Sbjct: 698 EKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKE 757 Query: 708 ESGSGESSSESDNED-----------QDEDEEKGRGSESEQSEEDGKRKTKK-------- 748 E E E + E+ +++ EE+G E E+ E +G+ + K+ Sbjct: 758 EGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGG 817 Query: 749 KVPERKGEASSSDEGSDSSSSSSE-SEMTSESEEEQLE 785 +V E KGE +E + E E E EEE+ E Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGE 855 Score = 50.8 bits (120), Expect = 7e-06 Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 9/123 (7%) Query: 668 EKRKEKEKPFYSDSEGE------SGPTESADSDPESESESDSKSSSESGSGESSSESDNE 721 E+ E E + EGE G E + + E E E + + E G GE E Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGE-EEEGEGEGEDGEGEGEEEEGEW 955 Query: 722 DQDEDEEKGRGSESEQSE-EDGKRKTKKKVPERKG-EASSSDEGSDSSSSSSESEMTSES 779 + +E+E +G G E + E E+G+ + +++ E +G E +EG + E E E Sbjct: 956 EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE 1015 Query: 780 EEE 782 EEE Sbjct: 1016 EEE 1018 Score = 50.4 bits (119), Expect = 9e-06 Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 17/126 (13%) Query: 666 NREKRKEKEKPFYSDSEG-ESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQD 724 +RE+ +EKE EG E G E + + E E E + K +G E E ++ + Sbjct: 744 DREEEEEKE------GEGKEEGEGEEVEGEREKE-EGERKKEERAGKEEKGEEEGDQGEG 796 Query: 725 EDEE-KGRGSESEQ-------SEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMT 776 E+EE +GRG E E+ E+GK + +++ E +GE EG + E E Sbjct: 797 EEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGE-EEEGEGEEEEGEGEEEEGE 855 Query: 777 SESEEE 782 + EEE Sbjct: 856 GKGEEE 861 Score = 50.4 bits (119), Expect = 9e-06 Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 7/119 (5%) Query: 668 EKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDE 727 E ++KE+ + +GE + + E+E + K G E E ++E+E Sbjct: 772 EGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEE 831 Query: 728 E-KGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLE 785 E +G E E EE+G+ + E +GE +EG + E E EEE+ E Sbjct: 832 EGEGEEEEGEGEEEEGEGE------EEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884 Score = 49.3 bits (116), Expect = 2e-05 Identities = 48/207 (23%), Positives = 75/207 (36%), Gaps = 34/207 (16%) Query: 590 EQGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAP 649 ++G A +H + +PA +E+ F D + E+P+ E A Sbjct: 554 KEGKACKQHVSQGIFMTQPATTIEA-FSDEE------------------VEIPEEKEGAE 594 Query: 650 DPSVRNVEVPEWTKCSNREK----RKEKEKPFYSD-------SEGESGPTESADSDPESE 698 D +E E K RKEK + D SEG++ A+ PE Sbjct: 595 DSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGR 654 Query: 699 SESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEAS 758 + + E GS + D E + +++KGRG E + + K++ +R GE Sbjct: 655 GDG----TCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQ 710 Query: 759 SSDEGSDSSSSSSESEMTSESEEEQLE 785 E EM EEE E Sbjct: 711 EQKEREQGHQKERNQEMEEGGEEEHGE 737 Score = 43.9 bits (102), Expect = 8e-04 Identities = 38/151 (25%), Positives = 62/151 (41%), Gaps = 21/151 (13%) Query: 644 WPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDS 703 W +E + ++ E + EK EK + +GE E + E + + Sbjct: 669 WQDEEREKGEKDKGRGEMERPGEGEKELA-EKEEWKKRDGE----EQEQKEREQGHQKER 723 Query: 704 KSSSESGSGESSSESDNEDQD-EDEEKGRGS----------ESEQSEEDGKRKTKKKV-P 751 E G E E + E+ D E+EE+ G E E+ +E+G+RK +++ Sbjct: 724 NQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGK 783 Query: 752 ERKGEASSSDEGSDSSSSSSESEMTSESEEE 782 E KGE +EG E+E E +EE Sbjct: 784 EEKGE----EEGDQGEGEEEETEGRGEEKEE 810 Score = 41.2 bits (95), Expect = 0.005 Identities = 32/155 (20%), Positives = 56/155 (36%), Gaps = 10/155 (6%) Query: 634 KATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGE-----SGPT 688 KA E D PE D + E + + + +E+EK GE G Sbjct: 640 KAKSVGEAEDGPEGRGDGTCE-----EGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEK 694 Query: 689 ESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKK 748 E A+ + + + + + E G + ++ +EE G G E E E+ + K + Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754 Query: 749 KVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQ 783 E +GE + + E E + E+ Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE 789 Score = 40.0 bits (92), Expect = 0.012 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 12/120 (10%) Query: 668 EKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDE 727 E +E+E + EGE G E + + E E E K GE N +++E+E Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKE------GEGEENRRNREEEEEE 1065 Query: 728 EKGRGSESEQSEEDGKR---KTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQL 784 E G E EE+ +R + KKV + KG + S + ++ + + ++ Sbjct: 1066 E---GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKM 1122 >gi|115529449 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 60.8 bits (146), Expect = 7e-09 Identities = 34/101 (33%), Positives = 49/101 (48%), Gaps = 2/101 (1%) Query: 671 KEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKG 730 K S SE E E D + E E E D ++ S G SSES +ED+ ED ++ Sbjct: 628 KSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDE- 686 Query: 731 RGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSS 771 E ++ E+D + + + E +G +SSS DSS S S Sbjct: 687 -NEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726 Score = 51.2 bits (121), Expect = 5e-06 Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 11/135 (8%) Query: 656 VEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESS 715 V + W K + + R ++ Y ++ +S + S + SKS SE E Sbjct: 591 VHLDLWVKSLSPQDRAAYKE--YISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDE 648 Query: 716 SESDNEDQDEDEEKGRGSE---------SEQSEEDGKRKTKKKVPERKGEASSSDEGSDS 766 + D ++++ED+E G SE SE EDG + E E DE ++S Sbjct: 649 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708 Query: 767 SSSSSESEMTSESEE 781 SSS S + +S + Sbjct: 709 EGSSSSSSSSGDSSD 723 Score = 45.8 bits (107), Expect = 2e-04 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 14/113 (12%) Query: 688 TESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTK 747 T+ +P+S S + +S SES E E D +D+DEDEE+ + SE+ G Sbjct: 620 TKLRGPNPKS-SRTTLQSKSES---EEDDEEDEDDEDEDEEEEDDENGDSSEDGGD---- 671 Query: 748 KKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSA 800 E+SS DE D + + E + E++ + + S + SS S+ Sbjct: 672 ------SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718 Score = 34.3 bits (77), Expect = 0.65 Identities = 19/78 (24%), Positives = 35/78 (44%) Query: 643 DWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESD 702 D E+ + N + E S+ +++ + + E + + D D + ++ES+ Sbjct: 650 DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709 Query: 703 SKSSSESGSGESSSESDN 720 SSS S SG+SS N Sbjct: 710 GSSSSSSSSGDSSDSDSN 727 >gi|115529451 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 60.8 bits (146), Expect = 7e-09 Identities = 34/101 (33%), Positives = 49/101 (48%), Gaps = 2/101 (1%) Query: 671 KEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKG 730 K S SE E E D + E E E D ++ S G SSES +ED+ ED ++ Sbjct: 628 KSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDE- 686 Query: 731 RGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSS 771 E ++ E+D + + + E +G +SSS DSS S S Sbjct: 687 -NEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726 Score = 51.2 bits (121), Expect = 5e-06 Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 11/135 (8%) Query: 656 VEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESS 715 V + W K + + R ++ Y ++ +S + S + SKS SE E Sbjct: 591 VHLDLWVKSLSPQDRAAYKE--YISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDE 648 Query: 716 SESDNEDQDEDEEKGRGSE---------SEQSEEDGKRKTKKKVPERKGEASSSDEGSDS 766 + D ++++ED+E G SE SE EDG + E E DE ++S Sbjct: 649 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708 Query: 767 SSSSSESEMTSESEE 781 SSS S + +S + Sbjct: 709 EGSSSSSSSSGDSSD 723 Score = 45.8 bits (107), Expect = 2e-04 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 14/113 (12%) Query: 688 TESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTK 747 T+ +P+S S + +S SES E E D +D+DEDEE+ + SE+ G Sbjct: 620 TKLRGPNPKS-SRTTLQSKSES---EEDDEEDEDDEDEDEEEEDDENGDSSEDGGD---- 671 Query: 748 KKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSA 800 E+SS DE D + + E + E++ + + S + SS S+ Sbjct: 672 ------SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718 Score = 34.3 bits (77), Expect = 0.65 Identities = 19/78 (24%), Positives = 35/78 (44%) Query: 643 DWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESD 702 D E+ + N + E S+ +++ + + E + + D D + ++ES+ Sbjct: 650 DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709 Query: 703 SKSSSESGSGESSSESDN 720 SSS S SG+SS N Sbjct: 710 GSSSSSSSSGDSSDSDSN 727 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 60.8 bits (146), Expect = 7e-09 Identities = 34/101 (33%), Positives = 49/101 (48%), Gaps = 2/101 (1%) Query: 671 KEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKG 730 K S SE E E D + E E E D ++ S G SSES +ED+ ED ++ Sbjct: 665 KSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDE- 723 Query: 731 RGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSS 771 E ++ E+D + + + E +G +SSS DSS S S Sbjct: 724 -NEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 763 Score = 51.2 bits (121), Expect = 5e-06 Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 11/135 (8%) Query: 656 VEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESS 715 V + W K + + R ++ Y ++ +S + S + SKS SE E Sbjct: 628 VHLDLWVKSLSPQDRAAYKE--YISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDE 685 Query: 716 SESDNEDQDEDEEKGRGSE---------SEQSEEDGKRKTKKKVPERKGEASSSDEGSDS 766 + D ++++ED+E G SE SE EDG + E E DE ++S Sbjct: 686 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 745 Query: 767 SSSSSESEMTSESEE 781 SSS S + +S + Sbjct: 746 EGSSSSSSSSGDSSD 760 Score = 45.8 bits (107), Expect = 2e-04 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 14/113 (12%) Query: 688 TESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTK 747 T+ +P+S S + +S SES E E D +D+DEDEE+ + SE+ G Sbjct: 657 TKLRGPNPKS-SRTTLQSKSES---EEDDEEDEDDEDEDEEEEDDENGDSSEDGGD---- 708 Query: 748 KKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSA 800 E+SS DE D + + E + E++ + + S + SS S+ Sbjct: 709 ------SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 755 Score = 34.3 bits (77), Expect = 0.65 Identities = 19/78 (24%), Positives = 35/78 (44%) Query: 643 DWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESD 702 D E+ + N + E S+ +++ + + E + + D D + ++ES+ Sbjct: 687 DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 746 Query: 703 SKSSSESGSGESSSESDN 720 SSS S SG+SS N Sbjct: 747 GSSSSSSSSGDSSDSDSN 764 >gi|217330641 IWS1 homolog [Homo sapiens] Length = 819 Score = 60.1 bits (144), Expect = 1e-08 Identities = 55/187 (29%), Positives = 86/187 (45%), Gaps = 28/187 (14%) Query: 646 EEAPDPSVRNVEV--PEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESE----- 698 EE P P + + E P + S+ E +E KP SDSE E GP + SD E+E Sbjct: 266 EELPKPRISDSESEDPPRNQASDSEN-EELPKPRVSDSESE-GPQKGPASDSETEDASRH 323 Query: 699 -----SESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQ---------SEEDGKR 744 S+ DS ++ E ++S + D D +K S+SE+ S+ED K Sbjct: 324 KQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKE 383 Query: 745 KTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPAS----WSRKTPPSSKSA 800 ++KV +RK A SD + +S+ +S + S++++ + S KT S Sbjct: 384 GEEEKVAKRKA-AVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEE 442 Query: 801 PATKEIS 807 A KE+S Sbjct: 443 EAGKELS 449 Score = 54.7 bits (130), Expect = 5e-07 Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 1/135 (0%) Query: 646 EEAPDPSVRNVEVPEWTKCSNREKRKEK-EKPFYSDSEGESGPTESADSDPESESESDSK 704 EE P P V + E E + + E+ KP SDSE E P A E Sbjct: 214 EELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRI 273 Query: 705 SSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGS 764 S SES + SD+E+++ + + SESE ++ ++ + R + SD+ S Sbjct: 274 SDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDS 333 Query: 765 DSSSSSSESEMTSES 779 D + ++EM ++S Sbjct: 334 DRENKGEDTEMQNDS 348 Score = 53.9 bits (128), Expect = 8e-07 Identities = 56/195 (28%), Positives = 78/195 (40%), Gaps = 22/195 (11%) Query: 646 EEAPDPSVRNVEV--PEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDS 703 EE P P + + E P + S+ E +E KP SDSE E P A E Sbjct: 240 EELPKPRISDSESEDPPRHQASDSEN-EELPKPRISDSESEDPPRNQASDSENEELPKPR 298 Query: 704 KSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEG 763 S SES + SD+E +D K + +S++D R+ K + E + ++ SD Sbjct: 299 VSDSESEGPQKGPASDSETEDASRHK----QKPESDDDSDRENKGEDTEMQNDSFHSDSH 354 Query: 764 SDSS---SSSSESEM-------TSESEEEQLEPASWSRKTPPSSKS-----APATKEISL 808 D SS SE E + E E+E E RK S S A A K + Sbjct: 355 MDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVV 414 Query: 809 LDLEDFTPPSVQPVS 823 D +D +V S Sbjct: 415 SDADDSDSDAVSDKS 429 Score = 49.7 bits (117), Expect = 2e-05 Identities = 51/216 (23%), Positives = 86/216 (39%), Gaps = 35/216 (16%) Query: 632 NAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKE----KEKPFYSDSEGESGP 687 ++++ G Q+ P E D S R+ + PE S+RE + E + F+SDS + Sbjct: 301 DSESEGPQKGPASDSETEDAS-RHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKK 359 Query: 688 TESADSDPESESESDSKSSSESGSGESSSE--------SDNEDQDEDEEKGRGSESEQSE 739 S+DS+ E + S + GE SD+ED+++ K S+ + Sbjct: 360 FHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADD 419 Query: 740 EDGKRKTKKKVPERKGEASSSDE-----------------GSDSSSSSSESEMTSE---- 778 D + K K AS S+E GSDS S + E + ++ Sbjct: 420 SDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGE 479 Query: 779 -SEEEQLEPASWSRKTPPSSKSAPATKEISLLDLED 813 +EE+ E ++++ K KE D +D Sbjct: 480 SGDEEEEEFTGFNQEDLEEEKGETQVKEAEDSDSDD 515 Score = 48.9 bits (115), Expect = 3e-05 Identities = 40/154 (25%), Positives = 58/154 (37%), Gaps = 7/154 (4%) Query: 657 EVPEWTKCSNREKRKEKE-KPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESS 715 E+ E K + E KP SDSE E P A E S SES Sbjct: 160 EIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKP 219 Query: 716 SESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEG------SDSSSS 769 SD+E ++ + SE+E+ + ++ + P R + S +E SDS S Sbjct: 220 QVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESE 279 Query: 770 SSESEMTSESEEEQLEPASWSRKTPPSSKSAPAT 803 S+SE E+L S + PA+ Sbjct: 280 DPPRNQASDSENEELPKPRVSDSESEGPQKGPAS 313 Score = 47.0 bits (110), Expect = 1e-04 Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 13/188 (6%) Query: 646 EEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSE------GESGPTESADSDPESES 699 EE +P + E + + + + +E K SDSE G + +E+ D S Sbjct: 98 EERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPAS 157 Query: 700 ESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASS 759 +S+ + +S + +S +E + Q D E + S+ + + K ++ + + E Sbjct: 158 DSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELP 217 Query: 760 SDEGSDSSSSSSESEMTSESEEEQLEPASWS---RKTPPSSKSAPATKE----ISLLDLE 812 + SDS S S+SE E+L S + PP +++ + E + D E Sbjct: 218 KPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSE 277 Query: 813 DFTPPSVQ 820 PP Q Sbjct: 278 SEDPPRNQ 285 Score = 46.6 bits (109), Expect = 1e-04 Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 10/146 (6%) Query: 646 EEAPDPSVRNVEVPEWTKC-SNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSK 704 E+A P + + E E + ++ + +E KP SDSE E P SD ESE E Sbjct: 175 EDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQV-SDSESE-EPPRH 232 Query: 705 SSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGS 764 +S+S + E ++ + ED + + S+SE E K ++ + + E ++ S Sbjct: 233 QASDSENEELPKPRISDSESEDPPRHQASDSENEE-----LPKPRISDSESEDPPRNQAS 287 Query: 765 DSSSSSSESEMTSESEEE--QLEPAS 788 DS + S+SE E Q PAS Sbjct: 288 DSENEELPKPRVSDSESEGPQKGPAS 313 Score = 46.2 bits (108), Expect = 2e-04 Identities = 40/151 (26%), Positives = 65/151 (43%), Gaps = 20/151 (13%) Query: 657 EVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESD---SKSSSESGSGE 713 E P + S+ E +E KP SDSE E P A SD E+E S S SE Sbjct: 201 EEPPKPRMSDSES-EELPKPQVSDSESEEPPRHQA-SDSENEELPKPRISDSESEDPPRH 258 Query: 714 SSSESDNED---------QDEDEEKGRGSESEQSE------EDGKRKTKKKVPERKGEAS 758 +S+S+NE+ + ED + + S+SE E D + + +K P E Sbjct: 259 QASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETE 318 Query: 759 SSDEGSDSSSSSSESEMTSESEEEQLEPASW 789 + S +S+ ++ E+ +++ S+ Sbjct: 319 DASRHKQKPESDDDSDRENKGEDTEMQNDSF 349 Score = 43.5 bits (101), Expect = 0.001 Identities = 36/138 (26%), Positives = 61/138 (44%), Gaps = 15/138 (10%) Query: 688 TESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTK 747 T+S + +P + + SDS ES +SD+E ++ E SE+E + G Sbjct: 67 TDSENDEPLNLNASDS----ESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSES 122 Query: 748 KKVPERKGEASSSDEGSDSSSSSSESE-----MTSESEEEQLEPASWSRKTPPSSKSAPA 802 ++ + G S ++E + +S SE+E S+SE E+L+ K+P S Sbjct: 123 EETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQ------KSPASDSETED 176 Query: 803 TKEISLLDLEDFTPPSVQ 820 + + D E PP Q Sbjct: 177 ALKPQISDSESEEPPRHQ 194 Score = 42.4 bits (98), Expect = 0.002 Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 15/130 (11%) Query: 674 EKPFYSDSEGESGPTESADSDPESESES-DSKSSSESGSGESSSESDNEDQDEDEEKG-- 730 + +YS + + G + +S S+ D + SGS S E +E++ D E G Sbjct: 2 DSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLP 61 Query: 731 RGSESEQSEED------GKRKTKKKVPERKGEASSSDEGSDSSSSSSESE------MTSE 778 +G SE D +++ +K S S+E ++ +S SE+E SE Sbjct: 62 KGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSE 121 Query: 779 SEEEQLEPAS 788 SEE + P S Sbjct: 122 SEETRKLPGS 131 Score = 41.6 bits (96), Expect = 0.004 Identities = 53/233 (22%), Positives = 90/233 (38%), Gaps = 24/233 (10%) Query: 612 LESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKR- 670 ++S + D G + + + + +G D E+ +VE + S+RE Sbjct: 1 MDSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGL 60 Query: 671 --------KEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNED 722 E ++P ++ D +SESE ++ + E ++ ++ Sbjct: 61 PKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDS 120 Query: 723 QDEDEEKGRGSESEQSE-EDGKRKTKKKVPERKGEASSS--DEGSDSSSSSSESE----- 774 + E+ K GS+SE E +G + K AS S +E S +S SE+E Sbjct: 121 ESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKP 180 Query: 775 --MTSESEEEQLEPASWS-RKTPPSSKSAPATKE----ISLLDLEDFTPPSVQ 820 SESEE AS S + PP + + + E + D E PP Q Sbjct: 181 QISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQ 233 Score = 39.7 bits (91), Expect = 0.016 Identities = 64/250 (25%), Positives = 104/250 (41%), Gaps = 51/250 (20%) Query: 668 EKRKEKEKPFYSDSEGESGPTESADSDPESES-ESDSKSSSESGS------GESSSESDN 720 +K ++EK SDSE E+G S + E + SDS+S +E + GES E + Sbjct: 427 DKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEE 486 Query: 721 E-----DQDEDEEKGRGS--ESEQSEEDGKRKTKKKVP---------ERKGEASSSDEGS 764 E +D +EEKG E+E S+ D K K + +RK S + Sbjct: 487 EFTGFNQEDLEEEKGETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRN 546 Query: 765 DSSSS--SSESEMTSESEEEQLEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPSV--- 819 + S ++ S + E A R+ +++ PA K+++LL P+V Sbjct: 547 RDGGTFISDADDVVSAMIVKMNEAAEEDRQL--NNQKKPALKKLTLL-------PAVVMH 597 Query: 820 ---QPVSPPAIVSTSLAADLEGLTLTDSTLVPSL---------LSPVSGVGRQELLHRVA 867 Q + I S ++A E L+ +P+L L + V ++ L H + Sbjct: 598 LKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLKILQELPSVSQETLKH--S 655 Query: 868 GEGLAVDYTF 877 G G AV Y + Sbjct: 656 GIGRAVMYLY 665 Score = 33.1 bits (74), Expect = 1.5 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 8/95 (8%) Query: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGR---GSES 735 SD G+ T ++DS+ E+ E K + E + SD+E +E+E G Sbjct: 426 SDKSGKREKTIASDSEEEAGKELSDKKNEE----KDLFGSDSESGNEEENLIADIFGESG 481 Query: 736 EQSEEDGKRKTKKKVPERKGEASSSD-EGSDSSSS 769 ++ EE+ ++ + E KGE + E SDS + Sbjct: 482 DEEEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDN 516 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 58.5 bits (140), Expect = 3e-08 Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 6/135 (4%) Query: 682 EGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEED 741 EGE+ ++ PE E E++++ E E+ +E +++ EDE + + E + Sbjct: 766 EGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNE 825 Query: 742 GKRKTKKKVPERKGEASSSDE------GSDSSSSSSESEMTSESEEEQLEPASWSRKTPP 795 G+ ++++ E GEA + ++ GSD S E E E EEE+ E + Sbjct: 826 GETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEE 885 Query: 796 SSKSAPATKEISLLD 810 + +E LD Sbjct: 886 EEEEEKGNEEPLSLD 900 Score = 40.4 bits (93), Expect = 0.009 Identities = 36/140 (25%), Positives = 54/140 (38%), Gaps = 23/140 (16%) Query: 645 PEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSK 704 P + P +V VP+ K +KE P + E+ ES P E E+ + Sbjct: 717 PAKLPAVTVTPAPVPDI-------KGDQKENPGGQEDVAEA---ESTGEMPGEEGETAGE 766 Query: 705 SSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGS 764 +E SG E+ E + E E +G+G E E E E KG+ DEG Sbjct: 767 GETEEKSG---GETQPEGEGETETQGKGEECEDENE----------AEGKGDNEGEDEGE 813 Query: 765 DSSSSSSESEMTSESEEEQL 784 + E+E ++L Sbjct: 814 IHAEDGEMKGNEGETESQEL 833 Score = 40.0 bits (92), Expect = 0.012 Identities = 46/215 (21%), Positives = 79/215 (36%), Gaps = 34/215 (15%) Query: 566 LAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLG 625 LAK + + AR Q S+ + + P P P ++ K+ G Sbjct: 687 LAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENP----G 742 Query: 626 SLSHLLNAKATGYQELP----------DWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEK 675 + A++TG E+P + E++ + E T+ E E E Sbjct: 743 GQEDVAEAESTG--EMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEA 800 Query: 676 PFYSDSEGES---------------GPTESADSDPESESESDSKSSSESGSGESSSESDN 720 D+EGE G TES + E+ E+ + G S Sbjct: 801 EGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSE 860 Query: 721 EDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKG 755 E+++E+EE+ E E+ EE + + +++ E KG Sbjct: 861 EEEEEEEEQ---EEEEEEEEQEEEEEEEEEEEEKG 892 Score = 35.0 bits (79), Expect = 0.38 Identities = 20/87 (22%), Positives = 43/87 (49%), Gaps = 8/87 (9%) Query: 666 NREKRKEKEKPFYSDSEG--ESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQ 723 ++E E +D +G + G ++ DS+ E E E + + E E + E++ Sbjct: 830 SQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEE------EEQEEEEE 883 Query: 724 DEDEEKGRGSESEQSEEDGKRKTKKKV 750 +E+EE+ +G+E S + + + K+ + Sbjct: 884 EEEEEEEKGNEEPLSLDWPETRQKQAI 910 >gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precursor [Homo sapiens] Length = 513 Score = 58.2 bits (139), Expect = 4e-08 Identities = 46/164 (28%), Positives = 74/164 (45%), Gaps = 18/164 (10%) Query: 646 EEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGES-GPTESADSDPESESESDSK 704 EE+ + + E + S++E E ++ S+S G++ PT S D E S+ Sbjct: 328 EESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEED 387 Query: 705 SSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGS 764 SS +S S + D + E ES +S ED E SSS EG Sbjct: 388 SSHTLSHSKSESREEQADSESSESLNFSEESPESPED--------------ENSSSQEGL 433 Query: 765 DSSSSSSES---EMTSESEEEQLEPASWSRKTPPSSKSAPATKE 805 S SSS+ES E SE ++ + +S S++ S++S +++E Sbjct: 434 QSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 477 Score = 47.8 bits (112), Expect = 6e-05 Identities = 42/159 (26%), Positives = 65/159 (40%), Gaps = 19/159 (11%) Query: 668 EKRKEKEKPFYSDSEGESGPTESADSD-PESESESDSKSSSESGSGESSSE------SDN 720 + R++ + DS+ ES + D P SES ++ SS+ S ES E DN Sbjct: 308 QPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDN 367 Query: 721 EDQD----EDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSS--------DEGSDSSS 768 D ED+E SE + S K++ + + E+S S + D +S Sbjct: 368 PDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENS 427 Query: 769 SSSESEMTSESEEEQLEPASWSRKTPPSSKSAPATKEIS 807 SS E + S E S S + S+ + +KE S Sbjct: 428 SSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDS 466 Score = 47.0 bits (110), Expect = 1e-04 Identities = 49/195 (25%), Positives = 84/195 (43%), Gaps = 15/195 (7%) Query: 625 GSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGE 684 G S N + +G +L + P R E + ++ + +E + SDS Sbjct: 243 GENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVK----SDSTEN 298 Query: 685 SGPTESADSDPESESESDS-KSSSESGSGESSSESDNEDQDEDEEKGRGSE--SEQSEED 741 S ++ S P +S+ DS + S E+ S E S D + +E S+ S +S+E+ Sbjct: 299 SNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEE 358 Query: 742 GKRKTKKKVPERKGEASSSDEGSDSS---SSSSESEMTSESEEEQL-----EPASWSRKT 793 +++ P+ E SDSS SS + S SES EEQ E ++S ++ Sbjct: 359 VVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEES 418 Query: 794 PPSSKSAPATKEISL 808 P S + ++ + L Sbjct: 419 PESPEDENSSSQEGL 433 Score = 41.2 bits (95), Expect = 0.005 Identities = 37/163 (22%), Positives = 69/163 (42%), Gaps = 17/163 (10%) Query: 623 QLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSE 682 Q +LS N+ + + + + + PDP+ VE E + S DS Sbjct: 342 QEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEE------------DSS 389 Query: 683 GESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDG 742 ++S + +++SE SSES + S ED++ ++G S S +E Sbjct: 390 HTLSHSKSESREEQADSE-----SSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQS 444 Query: 743 KRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLE 785 + ++ ++S S E S+S+ S S SE + + ++E Sbjct: 445 EESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIE 487 Score = 40.4 bits (93), Expect = 0.009 Identities = 36/153 (23%), Positives = 53/153 (34%), Gaps = 25/153 (16%) Query: 647 EAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEG------------------ESGPT 688 +AP P + + E E +K S+ E+ E EG +G Sbjct: 39 QAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKG 98 Query: 689 ESADSDPESESESDSKSSSESGSG-----ESSSESDNEDQDEDEEKGRGSESEQSEEDGK 743 D E +S D+ +SG G E + D+D D+ ES +D Sbjct: 99 GDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSA 158 Query: 744 RKTKKKVPERKGE--ASSSDEGSDSSSSSSESE 774 + T + E E S EG DS+ S E Sbjct: 159 QDTTSESRELDNEDRVDSKPEGGDSTQESESEE 191 Score = 37.7 bits (86), Expect = 0.059 Identities = 26/106 (24%), Positives = 47/106 (44%), Gaps = 5/106 (4%) Query: 679 SDSEGESGPTESADSDPES-ESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQ 737 S+ G + D+ ES E +++ + S+ G+S+ ES++E+ G GS+ E Sbjct: 147 SEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEH----WVGGGSDGES 202 Query: 738 SEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQ 783 S DG + + E+ S+ G+ +S+ S EQ Sbjct: 203 SHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQ 248 Score = 35.4 bits (80), Expect = 0.29 Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 10/106 (9%) Query: 689 ESADSDPESESESD---SKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRK 745 E DS ESESE S ES G+ S E D+E D+ + SE S + Sbjct: 179 EGGDSTQESESEEHWVGGGSDGESSHGDGS-ELDDEGMQSDDPESIRSERGNSRMNSAGM 237 Query: 746 TKKKVPERKGEASSSDEGSD------SSSSSSESEMTSESEEEQLE 785 K+ E +A++ D G S +S ++ E + +L+ Sbjct: 238 KSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELD 283 Score = 30.4 bits (67), Expect = 9.4 Identities = 34/152 (22%), Positives = 59/152 (38%), Gaps = 25/152 (16%) Query: 662 TKCSNREKRKEKEKPFYSDSEGESGPTESADS---------DPESESESDSKSSSES--- 709 T+ N E +E + ++ + P ES++S + +E SDS S E Sbjct: 20 TRYQNNESEDSEEWKGHL-AQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGS 78 Query: 710 ---------GSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSS 760 G S S D +D+E G ++ ++ G ++ E S Sbjct: 79 DDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQ--EGGNSRLGS 136 Query: 761 DEGSDSSSSSSESEMTSESEEEQLEPASWSRK 792 DE SD + +SE E + ++ + S SR+ Sbjct: 137 DEDSDDTIQASE-ESAPQGQDSAQDTTSESRE 167 >gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 precursor [Homo sapiens] Length = 497 Score = 58.2 bits (139), Expect = 4e-08 Identities = 46/164 (28%), Positives = 74/164 (45%), Gaps = 18/164 (10%) Query: 646 EEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGES-GPTESADSDPESESESDSK 704 EE+ + + E + S++E E ++ S+S G++ PT S D E S+ Sbjct: 312 EESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEED 371 Query: 705 SSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGS 764 SS +S S + D + E ES +S ED E SSS EG Sbjct: 372 SSHTLSHSKSESREEQADSESSESLNFSEESPESPED--------------ENSSSQEGL 417 Query: 765 DSSSSSSES---EMTSESEEEQLEPASWSRKTPPSSKSAPATKE 805 S SSS+ES E SE ++ + +S S++ S++S +++E Sbjct: 418 QSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 461 Score = 47.8 bits (112), Expect = 6e-05 Identities = 42/159 (26%), Positives = 65/159 (40%), Gaps = 19/159 (11%) Query: 668 EKRKEKEKPFYSDSEGESGPTESADSD-PESESESDSKSSSESGSGESSSE------SDN 720 + R++ + DS+ ES + D P SES ++ SS+ S ES E DN Sbjct: 292 QPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDN 351 Query: 721 EDQD----EDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSS--------DEGSDSSS 768 D ED+E SE + S K++ + + E+S S + D +S Sbjct: 352 PDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENS 411 Query: 769 SSSESEMTSESEEEQLEPASWSRKTPPSSKSAPATKEIS 807 SS E + S E S S + S+ + +KE S Sbjct: 412 SSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDS 450 Score = 47.0 bits (110), Expect = 1e-04 Identities = 49/195 (25%), Positives = 84/195 (43%), Gaps = 15/195 (7%) Query: 625 GSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGE 684 G S N + +G +L + P R E + ++ + +E + SDS Sbjct: 227 GENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVK----SDSTEN 282 Query: 685 SGPTESADSDPESESESDS-KSSSESGSGESSSESDNEDQDEDEEKGRGSE--SEQSEED 741 S ++ S P +S+ DS + S E+ S E S D + +E S+ S +S+E+ Sbjct: 283 SNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEE 342 Query: 742 GKRKTKKKVPERKGEASSSDEGSDSS---SSSSESEMTSESEEEQL-----EPASWSRKT 793 +++ P+ E SDSS SS + S SES EEQ E ++S ++ Sbjct: 343 VVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEES 402 Query: 794 PPSSKSAPATKEISL 808 P S + ++ + L Sbjct: 403 PESPEDENSSSQEGL 417 Score = 41.2 bits (95), Expect = 0.005 Identities = 37/163 (22%), Positives = 69/163 (42%), Gaps = 17/163 (10%) Query: 623 QLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSE 682 Q +LS N+ + + + + + PDP+ VE E + S DS Sbjct: 326 QEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEE------------DSS 373 Query: 683 GESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDG 742 ++S + +++SE SSES + S ED++ ++G S S +E Sbjct: 374 HTLSHSKSESREEQADSE-----SSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQS 428 Query: 743 KRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLE 785 + ++ ++S S E S+S+ S S SE + + ++E Sbjct: 429 EESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIE 471 Score = 37.7 bits (86), Expect = 0.059 Identities = 26/106 (24%), Positives = 47/106 (44%), Gaps = 5/106 (4%) Query: 679 SDSEGESGPTESADSDPES-ESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQ 737 S+ G + D+ ES E +++ + S+ G+S+ ES++E+ G GS+ E Sbjct: 131 SEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEH----WVGGGSDGES 186 Query: 738 SEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQ 783 S DG + + E+ S+ G+ +S+ S EQ Sbjct: 187 SHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQ 232 Score = 36.6 bits (83), Expect = 0.13 Identities = 33/140 (23%), Positives = 54/140 (38%), Gaps = 15/140 (10%) Query: 647 EAPDPSVRNVEVPEWTKCSNREKRKEKEKPF-----YSDSEGESGPTESADSDPESESES 701 +AP P + N + + T+ + + + +S S G+ G + D D +S Sbjct: 39 QAPTPPLANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDED---DSGD 95 Query: 702 DSKSSSESGSG-----ESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGE 756 D+ +SG G E + D+D D+ ES +D + T + E E Sbjct: 96 DTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNE 155 Query: 757 --ASSSDEGSDSSSSSSESE 774 S EG DS+ S E Sbjct: 156 DRVDSKPEGGDSTQESESEE 175 Score = 35.4 bits (80), Expect = 0.29 Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 10/106 (9%) Query: 689 ESADSDPESESESD---SKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRK 745 E DS ESESE S ES G+ S E D+E D+ + SE S + Sbjct: 163 EGGDSTQESESEEHWVGGGSDGESSHGDGS-ELDDEGMQSDDPESIRSERGNSRMNSAGM 221 Query: 746 TKKKVPERKGEASSSDEGSD------SSSSSSESEMTSESEEEQLE 785 K+ E +A++ D G S +S ++ E + +L+ Sbjct: 222 KSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELD 267 Score = 32.3 bits (72), Expect = 2.5 Identities = 29/126 (23%), Positives = 48/126 (38%), Gaps = 16/126 (12%) Query: 680 DSEGESGPTESADSDPESESESDSKSSSESGSGE-------------SSSESDNEDQDED 726 DSE G A + P + + + SE G G S S D +D Sbjct: 29 DSEEWKGHLAQAPTPPLANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDD 88 Query: 727 EEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEP 786 +E G ++ ++ G ++ E SDE SD + +SE E + ++ + Sbjct: 89 DEDDSGDDTFGDDDSGPGPKDRQ--EGGNSRLGSDEDSDDTIQASE-ESAPQGQDSAQDT 145 Query: 787 ASWSRK 792 S SR+ Sbjct: 146 TSESRE 151 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.129 0.357 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,589,431 Number of Sequences: 37866 Number of extensions: 1862725 Number of successful extensions: 32402 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 723 Number of HSP's successfully gapped in prelim test: 1070 Number of HSP's that attempted gapping in prelim test: 12033 Number of HSP's gapped (non-prelim): 10924 length of query: 1082 length of database: 18,247,518 effective HSP length: 113 effective length of query: 969 effective length of database: 13,968,660 effective search space: 13535631540 effective search space used: 13535631540 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.