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Search of human proteins with 34452709
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]
(757 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens] 1488 0.0
gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens] 1446 0.0
gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens] 1186 0.0
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 67 5e-11
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 67 5e-11
gi|164419758 bromodomain containing 2 [Homo sapiens] 67 5e-11
gi|4826806 bromodomain containing 2 [Homo sapiens] 67 5e-11
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 67 8e-11
gi|41350212 bromodomain containing 7 [Homo sapiens] 65 3e-10
gi|50345997 E1A binding protein p300 [Homo sapiens] 64 5e-10
gi|38788260 bromodomain PHD finger transcription factor isoform ... 61 3e-09
gi|38788274 bromodomain PHD finger transcription factor isoform ... 61 3e-09
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] 59 1e-08
gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens] 59 1e-08
gi|119943102 CREB binding protein isoform b [Homo sapiens] 59 1e-08
gi|119943104 CREB binding protein isoform a [Homo sapiens] 59 1e-08
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 59 2e-08
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 58 3e-08
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 58 3e-08
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 57 5e-08
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 57 6e-08
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 56 1e-07
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 56 1e-07
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 55 2e-07
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 54 4e-07
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 54 7e-07
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 53 9e-07
gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 53 9e-07
gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 53 9e-07
gi|41281917 polybromo 1 isoform 4 [Homo sapiens] 53 9e-07
>gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]
Length = 757
Score = 1488 bits (3853), Expect = 0.0
Identities = 757/757 (100%), Positives = 757/757 (100%)
Query: 1 MSFAMTLKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPL 60
MSFAMTLKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPL
Sbjct: 1 MSFAMTLKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPL 60
Query: 61 GDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPVTDDSPQKKMLG 120
GDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPVTDDSPQKKMLG
Sbjct: 61 GDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPVTDDSPQKKMLG 120
Query: 121 QKATPPPSPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLLEVGGVLPMIHGGE 180
QKATPPPSPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLLEVGGVLPMIHGGE
Sbjct: 121 QKATPPPSPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLLEVGGVLPMIHGGE 180
Query: 181 IQQTPNTVAASPAASESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVG 240
IQQTPNTVAASPAASESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVG
Sbjct: 181 IQQTPNTVAASPAASESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVG 240
Query: 241 DPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSY 300
DPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSY
Sbjct: 241 DPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSY 300
Query: 301 TGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQE 360
TGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQE
Sbjct: 301 TGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQE 360
Query: 361 RDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVA 420
RDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVA
Sbjct: 361 RDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVA 420
Query: 421 GVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSP 480
GVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSP
Sbjct: 421 GVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSP 480
Query: 481 SHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPK 540
SHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPK
Sbjct: 481 SHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPK 540
Query: 541 EEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAI 600
EEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAI
Sbjct: 541 EEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAI 600
Query: 601 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLI 660
QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLI
Sbjct: 601 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLI 660
Query: 661 RSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGIS 720
RSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGIS
Sbjct: 661 RSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGIS 720
Query: 721 AKSLRGRDSTRKQDASEKDGGTRGRRCAIEADMKMKK 757
AKSLRGRDSTRKQDASEKDGGTRGRRCAIEADMKMKK
Sbjct: 721 AKSLRGRDSTRKQDASEKDGGTRGRRCAIEADMKMKK 757
>gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]
Length = 951
Score = 1446 bits (3744), Expect = 0.0
Identities = 750/804 (93%), Positives = 750/804 (93%), Gaps = 54/804 (6%)
Query: 8 KKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTT 67
KKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTT
Sbjct: 148 KKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTT 207
Query: 68 MEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPVTDDSPQKKMLGQKATPPP 127
MEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPVTDDSPQKKMLGQKATPPP
Sbjct: 208 MEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPVTDDSPQKKMLGQKATPPP 267
Query: 128 SPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLLEVGGVLPMIHGGEIQQTPNT 187
SPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLLEVGGVLPMIHGGEIQQTPNT
Sbjct: 268 SPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLLEVGGVLPMIHGGEIQQTPNT 327
Query: 188 VAASPAAS---------------------------------------ESVSQATIVMMPA 208
VAASPAAS ESVSQATIVMMPA
Sbjct: 328 VAASPAASGAPTLSRLLEAGPTQFTTPLASFTTVASEPPVKLVPPPVESVSQATIVMMPA 387
Query: 209 LPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGDPHTVTVSMDSSEISMIINSIKEECFRS 268
LPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGDPHTVTVSMDSSEISMIINSIKEECFRS
Sbjct: 388 LPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGDPHTVTVSMDSSEISMIINSIKEECFRS 447
Query: 269 GVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGEELDFETVGDIIAIIEDKVDDHPEVL 328
GVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGEELDFETVGDIIAIIEDKVDDHPEVL
Sbjct: 448 GVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGEELDFETVGDIIAIIEDKVDDHPEVL 507
Query: 329 DVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQERLDFEETENKG 388
DVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQERLDFEETENKG
Sbjct: 508 DVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQERLDFEETENKG 567
Query: 389 IHELVDIREPSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELRSQDLDEELGSTAAG 448
IHELVDIREPSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELRSQDLDEELGSTAAG
Sbjct: 568 IHELVDIREPSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELRSQDLDEELGSTAAG 627
Query: 449 EIVEADVAIGKGDETPLTNVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEE 508
EIVEADVAIGKGDETPLTNVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEE
Sbjct: 628 EIVEADVAIGKGDETPLTNVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEE 687
Query: 509 SGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIH 568
SGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIH
Sbjct: 688 SGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIH 747
Query: 569 NATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQ 628
NATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQ
Sbjct: 748 NATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQ 807
Query: 629 PVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVY 688
PVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVY
Sbjct: 808 PVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVY 867
Query: 689 HMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEK---------- 738
HMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEK
Sbjct: 868 HMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSVPMGSPAF 927
Query: 739 -----DGGTRGRRCAIEADMKMKK 757
DGGTRGRRCAIEADMKMKK
Sbjct: 928 LLSLFDGGTRGRRCAIEADMKMKK 951
>gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]
Length = 1235
Score = 1186 bits (3069), Expect = 0.0
Identities = 639/745 (85%), Positives = 646/745 (86%), Gaps = 50/745 (6%)
Query: 8 KKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTT 67
KKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTT
Sbjct: 148 KKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTT 207
Query: 68 MEEATSG-------VTPGTLPSTPV-TSFPGIPDTLPPGSAPLEAPMTPVTDDSPQKKML 119
MEEATSG V G L ST V G+ + G E TP T +
Sbjct: 208 MEEATSGVNESEMAVASGHLNSTGVLLEVGGVLPMIHGG----EIQQTPNT--------V 255
Query: 120 GQKATPPPSPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLLEVGGVLPMIHGG 179
+P LS LL+ G T+P S VAS
Sbjct: 256 AASPAASGAPTLSRLLEAGPTQFTTPL---ASFTTVAS---------------------- 290
Query: 180 EIQQTPNTVAASPAASESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAV 239
+ P V P ESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAV
Sbjct: 291 ---EPP--VKLVPPPVESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAV 345
Query: 240 GDPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVS 299
GDPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVS
Sbjct: 346 GDPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVS 405
Query: 300 YTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQ 359
YTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQ
Sbjct: 406 YTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQ 465
Query: 360 ERDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIV 419
ERDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIV
Sbjct: 466 ERDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIV 525
Query: 420 AGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLS 479
AGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLS
Sbjct: 526 AGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLS 585
Query: 480 PSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEP 539
PSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEP
Sbjct: 586 PSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEP 645
Query: 540 KEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEA 599
KEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEA
Sbjct: 646 KEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEA 705
Query: 600 IQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGL 659
IQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGL
Sbjct: 706 IQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGL 765
Query: 660 IRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGI 719
IRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGI
Sbjct: 766 IRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGI 825
Query: 720 SAKSLRGRDSTRKQDASEKDGGTRG 744
SAKSLRGRDSTRKQDASEKD G
Sbjct: 826 SAKSLRGRDSTRKQDASEKDSVPMG 850
Score = 174 bits (441), Expect = 3e-43
Identities = 88/179 (49%), Positives = 128/179 (71%), Gaps = 10/179 (5%)
Query: 525 EEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSS 584
E E+G ++ +E K EDQGE Y+SEM+++PP E DD F+I L D++ S
Sbjct: 1037 ESEEGEAQ----QESKGEDQGEVYVSEMEDQPPSGECDDAFNIKETPL-----VDTLFSH 1087
Query: 585 PASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQR 644
SS+ + S+D + +Q ++KK ++ VW+ A+HR+++ FL+PV++ APGY +V+R
Sbjct: 1088 ATSSKLTDLSQD-DPVQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSERQAPGYKDVVKR 1146
Query: 645 PMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQ 703
PMDL+++K+N+ G IR+ A+F RD+MLMFQNAVMYN SDH VYHMAVEM+R+VLEQIQ
Sbjct: 1147 PMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREVLEQIQ 1205
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 67.4 bits (163), Expect = 5e-11
Identities = 68/233 (29%), Positives = 96/233 (41%), Gaps = 42/233 (18%)
Query: 474 PESMLSPSHGSNPIED--PLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVS 531
P+ P+ P++ P+ A T + +K ++ T + I D +
Sbjct: 255 PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI----------DPIH 304
Query: 532 EAASLE-EPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQF 590
E SL EPK G+ S +PP + D Q H + SS S Q
Sbjct: 305 EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS--------QQHPAPEK--SSKVSEQL 354
Query: 591 SVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHS---IVQRPMD 647
CS + + A+K + YA F +PV D A G H I++ PMD
Sbjct: 355 KCCSGILKEMFAKK--------------HAAYAWPFYKPV-DVEALGLHDYCDIIKHPMD 399
Query: 648 LSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLE 700
+STIK +E R EF D+ LMF N YN DH+V MA ++Q DV E
Sbjct: 400 MSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ-DVFE 451
Score = 67.0 bits (162), Expect = 6e-11
Identities = 48/171 (28%), Positives = 81/171 (47%), Gaps = 17/171 (9%)
Query: 573 QSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTD 632
Q A + P P +S + ++ Q Q + + + +W+ H++A F QPV D
Sbjct: 36 QPANAASTNPPPPETSNPN--KPKRQTNQLQYLLRVVLKTLWK----HQFAWPFQQPV-D 88
Query: 633 DIA---PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYH 689
+ P Y+ I++ PMD+ TIKK +EN + E +D MF N +YN D+
Sbjct: 89 AVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVL 148
Query: 690 MAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDG 740
MA +++ L++I + + T E+ I +GR RK+ + K G
Sbjct: 149 MAEALEKLFLQKINE-------LPTEETEIMIVQAKGRGRGRKETGTAKPG 192
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 67.4 bits (163), Expect = 5e-11
Identities = 68/233 (29%), Positives = 96/233 (41%), Gaps = 42/233 (18%)
Query: 474 PESMLSPSHGSNPIED--PLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVS 531
P+ P+ P++ P+ A T + +K ++ T + I D +
Sbjct: 255 PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI----------DPIH 304
Query: 532 EAASLE-EPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQF 590
E SL EPK G+ S +PP + D Q H + SS S Q
Sbjct: 305 EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS--------QQHPAPEK--SSKVSEQL 354
Query: 591 SVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHS---IVQRPMD 647
CS + + A+K + YA F +PV D A G H I++ PMD
Sbjct: 355 KCCSGILKEMFAKK--------------HAAYAWPFYKPV-DVEALGLHDYCDIIKHPMD 399
Query: 648 LSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLE 700
+STIK +E R EF D+ LMF N YN DH+V MA ++Q DV E
Sbjct: 400 MSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ-DVFE 451
Score = 67.0 bits (162), Expect = 6e-11
Identities = 48/171 (28%), Positives = 81/171 (47%), Gaps = 17/171 (9%)
Query: 573 QSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTD 632
Q A + P P +S + ++ Q Q + + + +W+ H++A F QPV D
Sbjct: 36 QPANAASTNPPPPETSNPN--KPKRQTNQLQYLLRVVLKTLWK----HQFAWPFQQPV-D 88
Query: 633 DIA---PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYH 689
+ P Y+ I++ PMD+ TIKK +EN + E +D MF N +YN D+
Sbjct: 89 AVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVL 148
Query: 690 MAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDG 740
MA +++ L++I + + T E+ I +GR RK+ + K G
Sbjct: 149 MAEALEKLFLQKINE-------LPTEETEIMIVQAKGRGRGRKETGTAKPG 192
Score = 30.4 bits (67), Expect = 6.4
Identities = 48/188 (25%), Positives = 66/188 (35%), Gaps = 35/188 (18%)
Query: 77 PGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPVTDDSPQKKMLGQKATPPP-----SPLL 131
P +P P P P PP + P P PQ+ K++PPP P+L
Sbjct: 750 PAPVPQQPPPP-PQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVL 808
Query: 132 SELLKKGSLL---------------PTSPRLVNESEMAVASGHLNSTGVLLEVGGVLPMI 176
L GS+ P P + + HLN V+ P +
Sbjct: 809 EPQL-PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSP-----PAL 862
Query: 177 HGGEIQQ--TPNTVAAS----PAASESVSQATIVMMPALPAPSSA-PAVSTTESVAPVSQ 229
H QQ P+ AA+ PA +VS A + P LP P A P E P +
Sbjct: 863 HNALPQQPSRPSNRAAALPPKPARPPAVSPA-LTQTPLLPQPPMAQPPQVLLEDEEPPAP 921
Query: 230 PDNCVPME 237
P + M+
Sbjct: 922 PLTSMQMQ 929
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 67.4 bits (163), Expect = 5e-11
Identities = 40/82 (48%), Positives = 49/82 (59%), Gaps = 5/82 (6%)
Query: 622 YANVFLQPVTDDIAPG---YHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAV 678
YA F +PV D A G YH I++ PMDLST+K+ +EN R EF D+ LMF N
Sbjct: 368 YAWPFYKPV-DASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCY 426
Query: 679 MYNSSDHDVYHMAVEMQRDVLE 700
YN DHDV MA ++Q DV E
Sbjct: 427 KYNPPDHDVVAMARKLQ-DVFE 447
Score = 64.3 bits (155), Expect = 4e-10
Identities = 40/142 (28%), Positives = 72/142 (50%), Gaps = 14/142 (9%)
Query: 601 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 657
Q Q + K + +W+ H++A F QPV D + P YH I+++PMD+ TIK+ +EN
Sbjct: 78 QLQYLHKVVMKALWK----HQFAWPFRQPV-DAVKLGLPDYHKIIKQPMDMGTIKRRLEN 132
Query: 658 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQI------QQFLATQLI 711
+ +E +D MF N +YN D+ MA +++ L+++ +Q L +
Sbjct: 133 NYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIP 192
Query: 712 MQTSESGISAKSLRGRDSTRKQ 733
+ + G +L+G ++ Q
Sbjct: 193 KNSHKKGAKLAALQGSVTSAHQ 214
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 67.4 bits (163), Expect = 5e-11
Identities = 40/82 (48%), Positives = 49/82 (59%), Gaps = 5/82 (6%)
Query: 622 YANVFLQPVTDDIAPG---YHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAV 678
YA F +PV D A G YH I++ PMDLST+K+ +EN R EF D+ LMF N
Sbjct: 368 YAWPFYKPV-DASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCY 426
Query: 679 MYNSSDHDVYHMAVEMQRDVLE 700
YN DHDV MA ++Q DV E
Sbjct: 427 KYNPPDHDVVAMARKLQ-DVFE 447
Score = 64.3 bits (155), Expect = 4e-10
Identities = 40/142 (28%), Positives = 72/142 (50%), Gaps = 14/142 (9%)
Query: 601 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 657
Q Q + K + +W+ H++A F QPV D + P YH I+++PMD+ TIK+ +EN
Sbjct: 78 QLQYLHKVVMKALWK----HQFAWPFRQPV-DAVKLGLPDYHKIIKQPMDMGTIKRRLEN 132
Query: 658 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQI------QQFLATQLI 711
+ +E +D MF N +YN D+ MA +++ L+++ +Q L +
Sbjct: 133 NYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIP 192
Query: 712 MQTSESGISAKSLRGRDSTRKQ 733
+ + G +L+G ++ Q
Sbjct: 193 KNSHKKGAKLAALQGSVTSAHQ 214
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 66.6 bits (161), Expect = 8e-11
Identities = 42/140 (30%), Positives = 68/140 (48%), Gaps = 9/140 (6%)
Query: 601 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 657
Q Q + + +W+ H++A F QPV D I P YH I++ PMD+ TIKK +EN
Sbjct: 38 QLQYMQNVVVKTLWK----HQFAWPFYQPV-DAIKLNLPDYHKIIKNPMDMGTIKKRLEN 92
Query: 658 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQL-IMQTSE 716
S +E +D MF N +YN D+ MA +++ L+++ Q ++ ++ +
Sbjct: 93 NYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAP 152
Query: 717 SGISAKSLRGRDSTRKQDAS 736
G K G S Q +
Sbjct: 153 KGKGRKPAAGAQSAGTQQVA 172
Score = 61.2 bits (147), Expect = 3e-09
Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 4/124 (3%)
Query: 622 YANVFLQPVTDDIAP--GYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVM 679
YA F +PV + YH I++ PMDLST+K+ ++ F D+ LMF N
Sbjct: 330 YAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYK 389
Query: 680 YNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSL-RGRDSTRKQDASEK 738
YN DH+V MA ++Q DV E + + + + +A + +G +S+R + S
Sbjct: 390 YNPPDHEVVAMARKLQ-DVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSS 448
Query: 739 DGGT 742
D G+
Sbjct: 449 DSGS 452
Score = 33.5 bits (75), Expect = 0.75
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 49 IDSASPGGDYPLGDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTP 108
+ S SP P + PT + TP + VTS P P PP A P+ P
Sbjct: 174 VSSVSPAT--PFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVP 231
Query: 109 VTDDSPQKKMLGQKA---TPPPSPL 130
T +KK + +KA TP S +
Sbjct: 232 PTPPVVKKKGVKRKADTTTPTTSAI 256
>gi|41350212 bromodomain containing 7 [Homo sapiens]
Length = 651
Score = 64.7 bits (156), Expect = 3e-10
Identities = 72/273 (26%), Positives = 114/273 (41%), Gaps = 37/273 (13%)
Query: 471 EASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGV 530
E + S S H S+ ED + + +HK K+ K PGE E G
Sbjct: 33 EVTELSTGSSGHDSSLFEDKNDHD-KHKDRKRKKRKKGE--------KQIPGE---EKGR 80
Query: 531 SEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLA--DSIPSSPASS 588
E+ K+ D+ ++NE +E D LQ H D P P +S
Sbjct: 81 KRRRVKEDKKKRDR-----DRVENE---AEKD---------LQCHAPVRLDLPPEKPLTS 123
Query: 589 QFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDL 648
+ QE ++ + ++A+ + R + F PVTD IAPGY I++ PMD
Sbjct: 124 SLA----KQEEVEQTPL-QEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDF 178
Query: 649 STIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLAT 708
ST+K+ I+N +S E + + LM NA++YN + Y A ++ ++ + Q
Sbjct: 179 STMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQ 238
Query: 709 QLIMQTSESGISAKSLRGRDSTRKQDASEKDGG 741
L K+ + +D T + E DGG
Sbjct: 239 SLKQSIDFMADLQKTRKQKDGTDTSQSGE-DGG 270
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 63.9 bits (154), Expect = 5e-10
Identities = 72/307 (23%), Positives = 117/307 (38%), Gaps = 31/307 (10%)
Query: 398 PSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAI 457
P ++ P P ++ V P+ P + Q STAA +
Sbjct: 873 PQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLL 932
Query: 458 GKGDETPLTNVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQI 517
TPL+ + PS S + AE Q E+ K E
Sbjct: 933 PPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVD------- 985
Query: 518 KDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTL 577
+ P + + ED +SE+ + E + E +E+ E + E +D
Sbjct: 986 QPEPADTQPED-ISESKVEDCKMESTETEERSTELKTE--IKEEEDQ------------- 1029
Query: 578 ADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANV-FLQPVTDDIA- 635
PS+ A+ + ++ I + ++A+M A ++ F QPV +
Sbjct: 1030 ----PSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLG 1085
Query: 636 -PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEM 694
P Y IV+ PMDLSTIK+ ++ G + ++ DI LMF NA +YN VY ++
Sbjct: 1086 IPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKL 1145
Query: 695 QRDVLEQ 701
+V EQ
Sbjct: 1146 S-EVFEQ 1151
Score = 35.0 bits (79), Expect = 0.26
Identities = 37/128 (28%), Positives = 50/128 (39%), Gaps = 22/128 (17%)
Query: 3 FAMTLKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGD 62
F + +K+KL +++ + ++ +QA RR M R+ + G P
Sbjct: 1805 FCLNIKQKLRQQQLQ---------HRLQQAQML--RRRMASMQRTGVVGQQQGLPSPT-P 1852
Query: 63 LTPTTMEEATSGVTPGTLPSTPVTSFP-GIPDTLPPGSAPLEAPMTPVTDDSPQKKMLGQ 121
TPTT G P+TP T P P PP S P P T Q K GQ
Sbjct: 1853 ATPTT--------PTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQ 1904
Query: 122 KATPPPSP 129
TPP P
Sbjct: 1905 -VTPPTPP 1911
Score = 31.6 bits (70), Expect = 2.9
Identities = 41/196 (20%), Positives = 63/196 (32%), Gaps = 20/196 (10%)
Query: 45 VRSPI-DSASPGGDYPLGDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSA-PL 102
V SPI S G L + + + P P TP + P I PP + P
Sbjct: 803 VNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTP-TPHHTPPSIGAQQPPATTIPA 861
Query: 103 EAPMTPVTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNS 162
P P PQ + L P+P ++L ++ + P+ P + + S
Sbjct: 862 PVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQ--VQPSLPAAPSADQPQQQPRSQQS 919
Query: 163 TGVLLEVGGVLPMIHGGEIQQTPNTVAASPAASESVSQATIVMMPALPAPSSAPAVSTTE 222
T + TP P + +SQ + + + P S +
Sbjct: 920 TAASVP---------------TPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNS 964
Query: 223 SVAPVSQPDNCVPMEA 238
QP V MEA
Sbjct: 965 QAIAEKQPSQEVKMEA 980
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 61.2 bits (147), Expect = 3e-09
Identities = 29/97 (29%), Positives = 54/97 (55%)
Query: 613 VWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIML 672
V R+ H+ A FL+PV + AP Y+ +++ PMDL+T+++ ++ EF D+
Sbjct: 2796 VLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK 2855
Query: 673 MFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQ 709
+F N YN SD Y A ++ +++++ F A++
Sbjct: 2856 IFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASR 2892
Score = 32.3 bits (72), Expect = 1.7
Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 523 EDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFS-IHNATLQSHTLADSI 581
E+EEEDG +E E EED+ E + D + + DD S ++ +SH+ S
Sbjct: 144 EEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSST 203
Query: 582 P 582
P
Sbjct: 204 P 204
Score = 30.4 bits (67), Expect = 6.4
Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 523 EDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDD 563
E+EEED VSE EE ++ D E SE D E + E DD
Sbjct: 134 EEEEEDMVSEE---EEEEDGDAEETQDSEDDEEDEMEEDDD 171
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 61.2 bits (147), Expect = 3e-09
Identities = 29/97 (29%), Positives = 54/97 (55%)
Query: 613 VWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIML 672
V R+ H+ A FL+PV + AP Y+ +++ PMDL+T+++ ++ EF D+
Sbjct: 2813 VLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK 2872
Query: 673 MFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQ 709
+F N YN SD Y A ++ +++++ F A++
Sbjct: 2873 IFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASR 2909
Score = 32.3 bits (72), Expect = 1.7
Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 523 EDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFS-IHNATLQSHTLADSI 581
E+EEEDG +E E EED+ E + D + + DD S ++ +SH+ S
Sbjct: 144 EEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSST 203
Query: 582 P 582
P
Sbjct: 204 P 204
Score = 30.4 bits (67), Expect = 6.4
Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 523 EDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDD 563
E+EEED VSE EE ++ D E SE D E + E DD
Sbjct: 134 EEEEEDMVSEE---EEEEDGDAEETQDSEDDEEDEMEEDDD 171
>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
Length = 597
Score = 59.3 bits (142), Expect = 1e-08
Identities = 30/66 (45%), Positives = 37/66 (56%)
Query: 626 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 685
F PVTD IAPGY I++ PMD T+K I +S EF+ D LM NA+ YN D
Sbjct: 161 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220
Query: 686 DVYHMA 691
Y +A
Sbjct: 221 VYYKLA 226
>gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens]
Length = 544
Score = 59.3 bits (142), Expect = 1e-08
Identities = 30/66 (45%), Positives = 37/66 (56%)
Query: 626 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 685
F PVTD IAPGY I++ PMD T+K I +S EF+ D LM NA+ YN D
Sbjct: 108 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 167
Query: 686 DVYHMA 691
Y +A
Sbjct: 168 VYYKLA 173
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 59.3 bits (142), Expect = 1e-08
Identities = 66/284 (23%), Positives = 116/284 (40%), Gaps = 32/284 (11%)
Query: 424 PATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHG 483
P T ++PP + + ++ + + + + + V T +S S + S
Sbjct: 892 PQTPVQPPSVATPQSSQQQPTPVHAQ--PPGTPLSQAAASIDNRVPTPSSVASAETNSQQ 949
Query: 484 SNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEED 543
P LE +T+ + E ++ ES K P + E+ + A+ ++E +
Sbjct: 950 PGPDVPVLEMKTETQAEDTEPDPGES--------KGEPRSEMMEEDLQGASQVKEETDIA 1001
Query: 544 QGEGYLSEMDNEPP---VSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAI 600
+ + E+D + P V ++ S N T T PS P F
Sbjct: 1002 EQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTS----PSQPRKKIFK--------- 1048
Query: 601 QAQKIWKKAIMLVWRAAANHRYANV-FLQPVTDDIA--PGYHSIVQRPMDLSTIKKNIEN 657
+ ++A+M A ++ F QPV + P Y IV+ PMDLSTIK+ ++
Sbjct: 1049 --PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDT 1106
Query: 658 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQ 701
G + ++ D+ LMF NA +YN VY ++ +V EQ
Sbjct: 1107 GQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKL-AEVFEQ 1149
Score = 38.1 bits (87), Expect = 0.030
Identities = 52/219 (23%), Positives = 73/219 (33%), Gaps = 38/219 (17%)
Query: 59 PLGDLTPTTMEEATSGVTPGTLPSTP-----VTSFPGIPDTLPPGSAPLEAPMTPVTDDS 113
PL L P + VT L TP P + T PPG P + P P +
Sbjct: 794 PLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQ-PAAPTQPST 852
Query: 114 PQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLLEVGGVL 173
P GQ TP P + S + + PT + V
Sbjct: 853 PVSSS-GQTPTPTPGSVPSATQTQST--PTVQAAAQAQVTPQPQTPVQPPSVATPQSS-- 907
Query: 174 PMIHGGEIQQTPNTVAASPAASESVSQATIVMMPALPAPSSAPAVST------------- 220
QQ P V A P + +SQA + +P PSS + T
Sbjct: 908 --------QQQPTPVHAQPPGT-PLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLE 958
Query: 221 --TESVAPVSQPDNCVPMEAVGDPHTVTVSMDSSEISMI 257
TE+ A ++PD P E+ G+P + + D S +
Sbjct: 959 MKTETQAEDTEPD---PGESKGEPRSEMMEEDLQGASQV 994
Score = 35.4 bits (80), Expect = 0.20
Identities = 32/129 (24%), Positives = 48/129 (37%), Gaps = 15/129 (11%)
Query: 40 LPTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVTPGTLP------STPVTSFPGIPD 93
+P++ +P P P TP + T TPG++P STP
Sbjct: 828 MPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQ 887
Query: 94 TLPPGSAPLEAPMTPVTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEM 153
P P++ P + T S Q++ A PP +PL + +PT
Sbjct: 888 VTPQPQTPVQPP-SVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPT--------PS 938
Query: 154 AVASGHLNS 162
+VAS NS
Sbjct: 939 SVASAETNS 947
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 59.3 bits (142), Expect = 1e-08
Identities = 66/284 (23%), Positives = 116/284 (40%), Gaps = 32/284 (11%)
Query: 424 PATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHG 483
P T ++PP + + ++ + + + + + V T +S S + S
Sbjct: 930 PQTPVQPPSVATPQSSQQQPTPVHAQ--PPGTPLSQAAASIDNRVPTPSSVASAETNSQQ 987
Query: 484 SNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEED 543
P LE +T+ + E ++ ES K P + E+ + A+ ++E +
Sbjct: 988 PGPDVPVLEMKTETQAEDTEPDPGES--------KGEPRSEMMEEDLQGASQVKEETDIA 1039
Query: 544 QGEGYLSEMDNEPP---VSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAI 600
+ + E+D + P V ++ S N T T PS P F
Sbjct: 1040 EQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTS----PSQPRKKIFK--------- 1086
Query: 601 QAQKIWKKAIMLVWRAAANHRYANV-FLQPVTDDIA--PGYHSIVQRPMDLSTIKKNIEN 657
+ ++A+M A ++ F QPV + P Y IV+ PMDLSTIK+ ++
Sbjct: 1087 --PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDT 1144
Query: 658 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQ 701
G + ++ D+ LMF NA +YN VY ++ +V EQ
Sbjct: 1145 GQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKL-AEVFEQ 1187
Score = 38.1 bits (87), Expect = 0.030
Identities = 52/219 (23%), Positives = 73/219 (33%), Gaps = 38/219 (17%)
Query: 59 PLGDLTPTTMEEATSGVTPGTLPSTP-----VTSFPGIPDTLPPGSAPLEAPMTPVTDDS 113
PL L P + VT L TP P + T PPG P + P P +
Sbjct: 832 PLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQ-PAAPTQPST 890
Query: 114 PQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLLEVGGVL 173
P GQ TP P + S + + PT + V
Sbjct: 891 PVSSS-GQTPTPTPGSVPSATQTQST--PTVQAAAQAQVTPQPQTPVQPPSVATPQSS-- 945
Query: 174 PMIHGGEIQQTPNTVAASPAASESVSQATIVMMPALPAPSSAPAVST------------- 220
QQ P V A P + +SQA + +P PSS + T
Sbjct: 946 --------QQQPTPVHAQPPGT-PLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLE 996
Query: 221 --TESVAPVSQPDNCVPMEAVGDPHTVTVSMDSSEISMI 257
TE+ A ++PD P E+ G+P + + D S +
Sbjct: 997 MKTETQAEDTEPD---PGESKGEPRSEMMEEDLQGASQV 1032
Score = 35.4 bits (80), Expect = 0.20
Identities = 32/129 (24%), Positives = 48/129 (37%), Gaps = 15/129 (11%)
Query: 40 LPTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVTPGTLP------STPVTSFPGIPD 93
+P++ +P P P TP + T TPG++P STP
Sbjct: 866 MPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQ 925
Query: 94 TLPPGSAPLEAPMTPVTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEM 153
P P++ P + T S Q++ A PP +PL + +PT
Sbjct: 926 VTPQPQTPVQPP-SVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPT--------PS 976
Query: 154 AVASGHLNS 162
+VAS NS
Sbjct: 977 SVASAETNS 985
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 58.9 bits (141), Expect = 2e-08
Identities = 26/77 (33%), Positives = 45/77 (58%)
Query: 620 HRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVM 679
H+ + FL+PV + AP Y+ I++ PMD+S+++K + GL + EF D+ MF+N
Sbjct: 453 HKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRK 512
Query: 680 YNSSDHDVYHMAVEMQR 696
YN + M+ ++R
Sbjct: 513 YNGESSEYTKMSDNLER 529
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 58.2 bits (139), Expect = 3e-08
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 601 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 657
Q Q + K + +W+ H ++ F +PV D + P Y++I++ PMDL+TIKK +EN
Sbjct: 31 QLQYLQKVVLKDLWK----HSFSWPFQRPV-DAVKLQLPDYYTIIKNPMDLNTIKKRLEN 85
Query: 658 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSE 716
+E D MF N +YN D+ MA +++ ++++ Q + ++ E
Sbjct: 86 KYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKE 144
Score = 57.0 bits (136), Expect = 6e-08
Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 616 AAANHRYANVFLQPVTDDIAPG---YHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIML 672
A + YA F PV D A G Y+ +V+ PMDL TIK+ ++N + +F D+ L
Sbjct: 285 AKKHFSYAWPFYNPV-DVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRL 343
Query: 673 MFQNAVMYNSSDHDVYHMAVEMQRDVLE 700
MF N YN DH+V MA M +DV E
Sbjct: 344 MFMNCYKYNPPDHEVVTMA-RMLQDVFE 370
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 58.2 bits (139), Expect = 3e-08
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 601 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 657
Q Q + K + +W+ H ++ F +PV D + P Y++I++ PMDL+TIKK +EN
Sbjct: 31 QLQYLQKVVLKDLWK----HSFSWPFQRPV-DAVKLQLPDYYTIIKNPMDLNTIKKRLEN 85
Query: 658 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSE 716
+E D MF N +YN D+ MA +++ ++++ Q + ++ E
Sbjct: 86 KYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKE 144
Score = 57.0 bits (136), Expect = 6e-08
Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 616 AAANHRYANVFLQPVTDDIAPG---YHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIML 672
A + YA F PV D A G Y+ +V+ PMDL TIK+ ++N + +F D+ L
Sbjct: 285 AKKHFSYAWPFYNPV-DVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRL 343
Query: 673 MFQNAVMYNSSDHDVYHMAVEMQRDVLE 700
MF N YN DH+V MA M +DV E
Sbjct: 344 MFMNCYKYNPPDHEVVTMA-RMLQDVFE 370
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 57.4 bits (137), Expect = 5e-08
Identities = 40/175 (22%), Positives = 74/175 (42%), Gaps = 31/175 (17%)
Query: 522 GEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSI 581
G+ E+ED S ++SL+ ++ + + ++ SI+ + +S T
Sbjct: 2012 GDTEDEDSASTSSSLKRGNKDLKKR-------------KMEENTSINLSKQESFTSVKK- 2057
Query: 582 PSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSI 641
P S ++CS ++ H A FL PV + PGY +
Sbjct: 2058 PKRDDSKDLALCS-----------------MILTEMETHEDAWPFLLPVNLKLVPGYKKV 2100
Query: 642 VQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 696
+++PMD STI++ + +G + F D+ L+F N +N D D+ M++
Sbjct: 2101 IKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRK 2155
Score = 32.7 bits (73), Expect = 1.3
Identities = 36/112 (32%), Positives = 50/112 (44%), Gaps = 24/112 (21%)
Query: 460 GDETPLTNVKTEASP-----ESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEE----SG 510
G++TP V ASP + S+ NP++ TQH + SL E+
Sbjct: 546 GNQTP---VMPSASPILHSQGKEKAVSNNVNPVK------TQHHSHPAKSLVEQFRGTDS 596
Query: 511 TIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESD 562
I S+ + EDEEED E EE E+D+ + SE D+ SESD
Sbjct: 597 DIPSSKDSEDSNEDEEEDDEEED---EEDDEDDESDDSQSESDSN---SESD 642
Score = 30.4 bits (67), Expect = 6.4
Identities = 21/93 (22%), Positives = 37/93 (39%), Gaps = 18/93 (19%)
Query: 523 EDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIP 582
ED+E+D ++ S + E EG E D++ ESD +++ + S+
Sbjct: 621 EDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVK 680
Query: 583 S------------------SPASSQFSVCSEDQ 597
S +P S+ ++CSE Q
Sbjct: 681 SPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQ 713
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
sapiens]
Length = 1205
Score = 57.0 bits (136), Expect = 6e-08
Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Query: 623 ANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNS 682
A++F +PV P Y + +PMD ST+++ +E+ L R+ EF+ D L+ N + YN+
Sbjct: 611 AHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNA 670
Query: 683 SDHDVYHMAVEMQRDV 698
D ++H A RD+
Sbjct: 671 KD-TIFHRAAVRLRDL 685
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 55.8 bits (133), Expect = 1e-07
Identities = 45/207 (21%), Positives = 87/207 (42%), Gaps = 13/207 (6%)
Query: 503 DSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESD 562
+S E+S + ++ E+EEE+ A P++ +G+ + PP + S
Sbjct: 1248 ESASEDSEDDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVI-----PPAARSG 1302
Query: 563 DGFSIHNATLQSHTLADSIPSSPASSQFSVCS---EDQEAIQAQKIWKKAIMLVWRAAAN 619
+ H+ S P +P V + + + + Q + + +
Sbjct: 1303 -----RRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVK 1357
Query: 620 HRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVM 679
+R++ F +PVT D A Y+ ++ PMD T++ G RS EF D+ +F NA +
Sbjct: 1358 YRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEV 1417
Query: 680 YNSSDHDVYHMAVEMQRDVLEQIQQFL 706
YN V V+ ++ ++ + + L
Sbjct: 1418 YNCRGSHVLSCMVKTEQCLVALLHKHL 1444
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 55.8 bits (133), Expect = 1e-07
Identities = 34/144 (23%), Positives = 70/144 (48%), Gaps = 12/144 (8%)
Query: 614 WRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLM 673
++ ++ + + VF+Q + P Y+ ++++P+D IK+ I N RS + ++D+ML+
Sbjct: 1397 YKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLL 1456
Query: 674 FQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQ-----------TSESGISAK 722
NA +N +Y ++ +Q V + +Q +A + + ES AK
Sbjct: 1457 CHNAQTFNLEGSQIYEDSIVLQ-SVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAK 1515
Query: 723 SLRGRDSTRKQDASEKDGGTRGRR 746
S++ + K+D +D G +R
Sbjct: 1516 SVKVKIKLNKKDDKGRDKGKGKKR 1539
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 55.1 bits (131), Expect = 2e-07
Identities = 34/141 (24%), Positives = 68/141 (48%), Gaps = 12/141 (8%)
Query: 617 AANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQN 676
++ + + VF+Q + P Y+ ++++P+D IK+ I N RS + ++D+ML+ N
Sbjct: 1418 SSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHN 1477
Query: 677 AVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQ-----------TSESGISAKSLR 725
A +N +Y ++ +Q V + +Q +A + + ES AKS++
Sbjct: 1478 AQTFNLEGSQIYEDSIVLQ-SVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVK 1536
Query: 726 GRDSTRKQDASEKDGGTRGRR 746
+ K+D +D G +R
Sbjct: 1537 VKIKLNKKDDKGRDKGKGKKR 1557
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 54.3 bits (129), Expect = 4e-07
Identities = 28/87 (32%), Positives = 46/87 (52%)
Query: 619 NHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAV 678
+H A FL+PV + GY I++ PMD ST+++ + G S+ EF D +L+F N
Sbjct: 1811 SHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQ 1870
Query: 679 MYNSSDHDVYHMAVEMQRDVLEQIQQF 705
+N D +V M+R + ++F
Sbjct: 1871 TFNEDDSEVGKAGHIMRRFFESRWEEF 1897
>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform D [Homo sapiens]
Length = 1616
Score = 53.5 bits (127), Expect = 7e-07
Identities = 58/301 (19%), Positives = 123/301 (40%), Gaps = 40/301 (13%)
Query: 461 DETPLTNVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEM--SDSLKEESGTIFGSQIK 518
DE P +K +A E + E ++H+ E+ SDSL E+ I+
Sbjct: 1308 DELPSWIIKDDAEVERLTCEEEE----EKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIE 1363
Query: 519 DAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLA 578
+ E+ EE+ + +S + ++ D G S + DD + A
Sbjct: 1364 EGTLEEIEEEVRQKKSSRKRKRDSDAGS---STPTTSTRSRDKDD--ESKKQKKRGRPPA 1418
Query: 579 DSIPSSPASSQFSVCSEDQEAIQAQKIWKKAI--MLVWRAAANHRYANVFLQPVTDDIAP 636
+ + +P + K KK + ++ ++ ++ + + VF+Q + P
Sbjct: 1419 EKLSPNPPN--------------LTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELP 1464
Query: 637 GYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 696
Y+ ++++P+D IK+ I N RS + ++D+ML+ QNA +N +Y ++ +Q
Sbjct: 1465 EYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQ- 1523
Query: 697 DVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDGGTRGRRCAIEADMKMK 756
V ++Q + + G +S +++ E+ + R ++ + K
Sbjct: 1524 SVFTSVRQKIEKE------------DDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRK 1571
Query: 757 K 757
+
Sbjct: 1572 E 1572
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 53.1 bits (126), Expect = 9e-07
Identities = 52/267 (19%), Positives = 112/267 (41%), Gaps = 48/267 (17%)
Query: 526 EEDGVSEAASLEEPKEEDQGEG--YLSEMDNEPPVSESDDGFSIHNATLQS--------- 574
++D E + EE +E+ G G + E+D ++E +I TL+
Sbjct: 1316 KDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKK 1375
Query: 575 -----HTLADSIPSSPASSQFSVCSEDQEAIQAQ-----------------KIWKKAI-- 610
+D+ S+P +S S +D+ Q + K KK +
Sbjct: 1376 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA 1435
Query: 611 MLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDI 670
++ ++ ++ + + VF+Q + P Y+ ++++P+D IK+ I N RS + ++D+
Sbjct: 1436 VIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDV 1495
Query: 671 MLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDST 730
ML+ QNA +N +Y ++ +Q V ++Q + + G +S
Sbjct: 1496 MLLCQNAQTFNLEGSLIYEDSIVLQ-SVFTSVRQKIEKE------------DDSEGEESE 1542
Query: 731 RKQDASEKDGGTRGRRCAIEADMKMKK 757
+++ E+ + R ++ + K+
Sbjct: 1543 EEEEGEEEGSESESRSVKVKIKLGRKE 1569
>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
Length = 1602
Score = 53.1 bits (126), Expect = 9e-07
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 10/154 (6%)
Query: 579 DSIPSSPASSQFSVCSEDQEAIQAQ--KIWKKAIMLVWRAAANHRYANVFLQPVTDDIAP 636
DS+ SS S S + ++ I+ Q KI ++ + R ++F+ + P
Sbjct: 465 DSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYP 524
Query: 637 GYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 696
Y+ I+ PMDL I+ NI N D+ LMF+NA YN VY+ A +++
Sbjct: 525 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 584
Query: 697 DVLEQIQQF--------LATQLIMQTSESGISAK 722
+ E+ ++ +A+ + + +SGIS K
Sbjct: 585 LLKEKRKELGPLPDDDDMASPKLKLSRKSGISPK 618
Score = 45.4 bits (106), Expect = 2e-04
Identities = 21/61 (34%), Positives = 36/61 (59%)
Query: 636 PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQ 695
P Y++I++ P+DL TI + I+NG +S +DI L+ +NA YN V+ A ++
Sbjct: 218 PDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIK 277
Query: 696 R 696
+
Sbjct: 278 K 278
Score = 42.4 bits (98), Expect = 0.002
Identities = 20/80 (25%), Positives = 41/80 (51%)
Query: 621 RYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMY 680
R + +FL+ + P Y+ +++PMD+ I+ ++ + D ++MF NA Y
Sbjct: 647 RLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTY 706
Query: 681 NSSDHDVYHMAVEMQRDVLE 700
N + +Y A+ + + +LE
Sbjct: 707 NEPESLIYKDALVLHKVLLE 726
Score = 41.6 bits (96), Expect = 0.003
Identities = 60/284 (21%), Positives = 108/284 (38%), Gaps = 56/284 (19%)
Query: 456 AIGKGDETPLTNVKTEASPESMLSPSHGS-NPIEDPLEAETQH------KFEMSDSLKEE 508
A+ K + N KT P S + S I +AE +H MS+ +
Sbjct: 247 AMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQ 306
Query: 509 SGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIH 568
G + + G + EED AA EE E + E S MD P
Sbjct: 307 GGRLSAITMALQYGSESEEDAALAAARYEEG--ESEAESITSFMDVSNPF---------- 354
Query: 569 NATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQ 628
+ L D++ S C +Q + A+ + + +Y
Sbjct: 355 ------YQLYDTVRS---------CRNNQGQLIAEPFY--------HLPSKKKY------ 385
Query: 629 PVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVY 688
P Y+ ++ P+ L I+ ++N + + D+ LMF+NA YN + +Y
Sbjct: 386 -------PDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIY 438
Query: 689 HMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRK 732
+++Q+ V++ ++ LA + ++ +S IS+ + + RK
Sbjct: 439 KRVLKLQQ-VMQAKKKELARRDDIEDGDSMISSATSDTGSAKRK 481
Score = 37.7 bits (86), Expect = 0.040
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 21/121 (17%)
Query: 645 PMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQ------RDV 698
P+ I+KN+EN R FQ + + + A N +D ++Y AVE+Q RD
Sbjct: 787 PLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDE 846
Query: 699 LEQIQQFLATQLIMQTSE---------------SGISAKSLRGRDSTRKQDASEKDGGTR 743
L + + L + + T++ I L+ + R+ + SE G
Sbjct: 847 LCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAA 906
Query: 744 G 744
G
Sbjct: 907 G 907
Score = 32.7 bits (73), Expect = 1.3
Identities = 16/59 (27%), Positives = 27/59 (45%)
Query: 636 PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEM 694
P Y+ +V +P+DL I++ ++ D L+F NA Y D Y A ++
Sbjct: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKL 140
>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
Length = 1582
Score = 53.1 bits (126), Expect = 9e-07
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 10/154 (6%)
Query: 579 DSIPSSPASSQFSVCSEDQEAIQAQ--KIWKKAIMLVWRAAANHRYANVFLQPVTDDIAP 636
DS+ SS S S + ++ I+ Q KI ++ + R ++F+ + P
Sbjct: 497 DSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYP 556
Query: 637 GYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 696
Y+ I+ PMDL I+ NI N D+ LMF+NA YN VY+ A +++
Sbjct: 557 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 616
Query: 697 DVLEQIQQF--------LATQLIMQTSESGISAK 722
+ E+ ++ +A+ + + +SGIS K
Sbjct: 617 LLKEKRKELGPLPDDDDMASPKLKLSRKSGISPK 650
Score = 45.4 bits (106), Expect = 2e-04
Identities = 21/61 (34%), Positives = 36/61 (59%)
Query: 636 PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQ 695
P Y++I++ P+DL TI + I+NG +S +DI L+ +NA YN V+ A ++
Sbjct: 218 PDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIK 277
Query: 696 R 696
+
Sbjct: 278 K 278
Score = 42.4 bits (98), Expect = 0.002
Identities = 20/80 (25%), Positives = 41/80 (51%)
Query: 621 RYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMY 680
R + +FL+ + P Y+ +++PMD+ I+ ++ + D ++MF NA Y
Sbjct: 679 RLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTY 738
Query: 681 NSSDHDVYHMAVEMQRDVLE 700
N + +Y A+ + + +LE
Sbjct: 739 NEPESLIYKDALVLHKVLLE 758
Score = 41.2 bits (95), Expect = 0.004
Identities = 24/97 (24%), Positives = 52/97 (53%), Gaps = 1/97 (1%)
Query: 636 PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQ 695
P Y+ ++ P+ L I+ ++N + + D+ LMF+NA YN + +Y +++Q
Sbjct: 418 PDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQ 477
Query: 696 RDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRK 732
+ V++ ++ LA + ++ +S IS+ + + RK
Sbjct: 478 Q-VMQAKKKELARRDDIEDGDSMISSATSDTGSAKRK 513
Score = 37.7 bits (86), Expect = 0.040
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 21/121 (17%)
Query: 645 PMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQ------RDV 698
P+ I+KN+EN R FQ + + + A N +D ++Y AVE+Q RD
Sbjct: 819 PLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDE 878
Query: 699 LEQIQQFLATQLIMQTSE---------------SGISAKSLRGRDSTRKQDASEKDGGTR 743
L + + L + + T++ I L+ + R+ + SE G
Sbjct: 879 LCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAA 938
Query: 744 G 744
G
Sbjct: 939 G 939
Score = 32.7 bits (73), Expect = 1.3
Identities = 16/59 (27%), Positives = 27/59 (45%)
Query: 636 PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEM 694
P Y+ +V +P+DL I++ ++ D L+F NA Y D Y A ++
Sbjct: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKL 140
>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
Length = 1582
Score = 53.1 bits (126), Expect = 9e-07
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 10/154 (6%)
Query: 579 DSIPSSPASSQFSVCSEDQEAIQAQ--KIWKKAIMLVWRAAANHRYANVFLQPVTDDIAP 636
DS+ SS S S + ++ I+ Q KI ++ + R ++F+ + P
Sbjct: 497 DSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYP 556
Query: 637 GYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 696
Y+ I+ PMDL I+ NI N D+ LMF+NA YN VY+ A +++
Sbjct: 557 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 616
Query: 697 DVLEQIQQF--------LATQLIMQTSESGISAK 722
+ E+ ++ +A+ + + +SGIS K
Sbjct: 617 LLKEKRKELGPLPDDDDMASPKLKLSRKSGISPK 650
Score = 45.4 bits (106), Expect = 2e-04
Identities = 21/61 (34%), Positives = 36/61 (59%)
Query: 636 PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQ 695
P Y++I++ P+DL TI + I+NG +S +DI L+ +NA YN V+ A ++
Sbjct: 218 PDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIK 277
Query: 696 R 696
+
Sbjct: 278 K 278
Score = 42.4 bits (98), Expect = 0.002
Identities = 20/80 (25%), Positives = 41/80 (51%)
Query: 621 RYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMY 680
R + +FL+ + P Y+ +++PMD+ I+ ++ + D ++MF NA Y
Sbjct: 679 RLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTY 738
Query: 681 NSSDHDVYHMAVEMQRDVLE 700
N + +Y A+ + + +LE
Sbjct: 739 NEPESLIYKDALVLHKVLLE 758
Score = 41.2 bits (95), Expect = 0.004
Identities = 24/97 (24%), Positives = 52/97 (53%), Gaps = 1/97 (1%)
Query: 636 PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQ 695
P Y+ ++ P+ L I+ ++N + + D+ LMF+NA YN + +Y +++Q
Sbjct: 418 PDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQ 477
Query: 696 RDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRK 732
+ V++ ++ LA + ++ +S IS+ + + RK
Sbjct: 478 Q-VMQAKKKELARRDDIEDGDSMISSATSDTGSAKRK 513
Score = 37.7 bits (86), Expect = 0.040
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 21/121 (17%)
Query: 645 PMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQ------RDV 698
P+ I+KN+EN R FQ + + + A N +D ++Y AVE+Q RD
Sbjct: 819 PLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDE 878
Query: 699 LEQIQQFLATQLIMQTSE---------------SGISAKSLRGRDSTRKQDASEKDGGTR 743
L + + L + + T++ I L+ + R+ + SE G
Sbjct: 879 LCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAA 938
Query: 744 G 744
G
Sbjct: 939 G 939
Score = 32.7 bits (73), Expect = 1.3
Identities = 16/59 (27%), Positives = 27/59 (45%)
Query: 636 PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEM 694
P Y+ +V +P+DL I++ ++ D L+F NA Y D Y A ++
Sbjct: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKL 140
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.126 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,227,420
Number of Sequences: 37866
Number of extensions: 1771240
Number of successful extensions: 11578
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 149
Number of HSP's successfully gapped in prelim test: 582
Number of HSP's that attempted gapping in prelim test: 8626
Number of HSP's gapped (non-prelim): 2687
length of query: 757
length of database: 18,247,518
effective HSP length: 110
effective length of query: 647
effective length of database: 14,082,258
effective search space: 9111220926
effective search space used: 9111220926
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.