Guide to the Human Genome
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Search of human proteins with 33438577

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33438577 coiled-coil domain containing 132 isoform b [Homo
sapiens]
         (327 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33438577 coiled-coil domain containing 132 isoform b [Homo sa...   637   0.0  
gi|62865871 coiled-coil domain containing 132 isoform a [Homo sa...   613   e-176
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       40   0.004
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    38   0.011
gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo s...    38   0.014
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    37   0.031
gi|221139761 zinc finger protein 853 [Homo sapiens]                    36   0.041
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    36   0.041
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    36   0.041
gi|154354990 ankyrin repeat domain 26 [Homo sapiens]                   35   0.070
gi|81295809 pericentrin [Homo sapiens]                                 34   0.16 
gi|38044112 restin isoform b [Homo sapiens]                            34   0.20 
gi|4506751 restin isoform a [Homo sapiens]                             34   0.20 
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    34   0.20 
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    33   0.26 
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    33   0.26 
gi|62899065 centrosomal protein 72 kDa [Homo sapiens]                  33   0.26 
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     33   0.35 
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    33   0.45 
gi|237858621 polyamine modulated factor 1 binding protein 1 isof...    32   0.59 
gi|237858619 polyamine modulated factor 1 binding protein 1 isof...    32   0.59 
gi|55770834 centromere protein F [Homo sapiens]                        32   0.59 
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    32   0.77 
gi|27436948 lamin A/C isoform 3 [Homo sapiens]                         32   1.0  
gi|5031875 lamin A/C isoform 2 [Homo sapiens]                          32   1.0  
gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens]               32   1.0  
gi|4885075 atonal homolog 1 [Homo sapiens]                             32   1.0  
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    32   1.0  
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi...    32   1.0  
gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Ho...    32   1.0  

>gi|33438577 coiled-coil domain containing 132 isoform b [Homo
           sapiens]
          Length = 327

 Score =  637 bits (1644), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV 60
           MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV
Sbjct: 1   MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV 60

Query: 61  YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE 120
           YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE
Sbjct: 61  YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE 120

Query: 121 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL 180
           RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL
Sbjct: 121 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL 180

Query: 181 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA 240
           QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA
Sbjct: 181 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA 240

Query: 241 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT 300
           LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT
Sbjct: 241 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT 300

Query: 301 DTKFQKLQYKDLCTVCSDLITIHISLL 327
           DTKFQKLQYKDLCTVCSDLITIHISLL
Sbjct: 301 DTKFQKLQYKDLCTVCSDLITIHISLL 327


>gi|62865871 coiled-coil domain containing 132 isoform a [Homo
           sapiens]
          Length = 964

 Score =  613 bits (1580), Expect = e-176
 Identities = 314/314 (100%), Positives = 314/314 (100%)

Query: 1   MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV 60
           MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV
Sbjct: 1   MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV 60

Query: 61  YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE 120
           YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE
Sbjct: 61  YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE 120

Query: 121 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL 180
           RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL
Sbjct: 121 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL 180

Query: 181 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA 240
           QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA
Sbjct: 181 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA 240

Query: 241 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT 300
           LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT
Sbjct: 241 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT 300

Query: 301 DTKFQKLQYKDLCT 314
           DTKFQKLQYKDLCT
Sbjct: 301 DTKFQKLQYKDLCT 314


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 59/234 (25%), Positives = 100/234 (42%), Gaps = 22/234 (9%)

Query: 35   EEFRELREQP--SDPQAEQELINSIEQVYF-SVDSFDIVKYELEKLPPVLNLQ-ELEAYR 90
            EE R + EQ   S   AEQELI + E+V      +  ++  + +    +  LQ E+E   
Sbjct: 1688 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAV 1747

Query: 91   DKLKQQQAAVSKKVADLI-----LEKQPAYVKELER--------VTSLQTGLQLAAVICT 137
             + +  +    K + D       L+K+      LER        +  LQ  L  A  I  
Sbjct: 1748 QECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAL 1807

Query: 138  NGRRHLNIAKEGFTQASLGLLANQRKR--QLLIGLLKSLRTIKTLQ-RTDVRLSEMLEEE 194
             G +      E   +   G L  ++KR  + + G+ KS R IK L  +T+     +L  +
Sbjct: 1808 KGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQ 1867

Query: 195  DYPGAIQLCLECQKAASTFKHYSCISELNS--KLQDTLEQIEEQLDVALSKICK 246
            D    +QL ++  K  +        + L+   K+Q  L++ EE+ D+A S++ K
Sbjct: 1868 DLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1921


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 60/234 (25%), Positives = 102/234 (43%), Gaps = 22/234 (9%)

Query: 35   EEFRELREQP--SDPQAEQELINSIEQVYFSVDSFDIVKYELEKLPPVLN-LQ-ELEAYR 90
            EE R + EQ   S   AEQELI + E+V         +  + +K+   L+ LQ E+E   
Sbjct: 1686 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAV 1745

Query: 91   DKLKQQQAAVSKKVADLI-----LEKQPAYVKELER--------VTSLQTGLQLAAVICT 137
             + +  +    K + D       L+K+      LER        +  LQ  L  A  I  
Sbjct: 1746 QECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAL 1805

Query: 138  NG-RRHLNIAKEGFTQASLGLLANQRKR-QLLIGLLKSLRTIKTLQ-RTDVRLSEMLEEE 194
             G ++ L   +    +    L A Q++  + + G+ KS R IK L  +T+     +L  +
Sbjct: 1806 KGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQ 1865

Query: 195  DYPGAIQLCLECQKAASTFKHYSCISELNS--KLQDTLEQIEEQLDVALSKICK 246
            D    +QL ++  K  +        + L+   K+Q  L++ EE+ D+A S++ K
Sbjct: 1866 DLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1919


>gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo
           sapiens]
          Length = 1050

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 39/149 (26%), Positives = 65/149 (43%), Gaps = 22/149 (14%)

Query: 10  RQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQE----LINSIEQVYFSVD 65
           +Q + +P +    +  I S R PGKEE   L+   S  QA +E    ++   E++Y  V 
Sbjct: 349 QQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVG 408

Query: 66  SFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAA----VSKKVADL--ILEKQPAYVKEL 119
            F   +               E +R KLK+Q+ A     ++K A++   +E+    +KE+
Sbjct: 409 EFSFEEI------------RAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEI 456

Query: 120 ERVTSLQTGLQLAAVICTNGRRHLNIAKE 148
           +     +TG Q    + T     L IA E
Sbjct: 457 QTTQQERTGDQQEETMPTKETTKLQIASE 485


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 36.6 bits (83), Expect = 0.031
 Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 20/218 (9%)

Query: 49   AEQELINSIEQVYF-SVDSFDIVKYELEKLPPVLNLQ-ELEAYRDKLKQQQAAVSKKVAD 106
            AEQEL+++ E+V      +  ++  + +    V  LQ E+E    + +  +    K + D
Sbjct: 1705 AEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITD 1764

Query: 107  LI-----LEKQPAYVKELER--------VTSLQTGLQLAAVICTNGRRHLNIAKEGFTQA 153
                   L+K+      LER        V  LQ  L  A  +   G +      E   + 
Sbjct: 1765 AAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRE 1824

Query: 154  SLGLLANQRKR--QLLIGLLKSLRTIKTLQ-RTDVRLSEMLEEEDYPGAIQLCLECQKAA 210
              G + N++KR  + + GL K  R +K L  +T+     +L  +D    +Q  ++  K  
Sbjct: 1825 LEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQ 1884

Query: 211  STFKHYSCISELNS--KLQDTLEQIEEQLDVALSKICK 246
            +        + L+   KLQ  LE+ EE+ D+A S++ K
Sbjct: 1885 AEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNK 1922


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 36.2 bits (82), Expect = 0.041
 Identities = 48/231 (20%), Positives = 103/231 (44%), Gaps = 4/231 (1%)

Query: 11  QGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQA-EQELINSIEQVYFSVDSFDI 69
           Q LK   + +     ++  +V  ++  ++ +EQ    QA EQ+++   EQ+   V    +
Sbjct: 144 QELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQL 203

Query: 70  VKYELEKLPPVLNLQELE-AYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQTG 128
           ++ + E+L     LQ+ E   + + +QQQ  + ++   L+L++Q    ++L +    Q  
Sbjct: 204 LQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQ 263

Query: 129 LQLAAVICTNGRRHLNI-AKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRL 187
            QL        ++ L +  +E   Q     L  Q++ QL    L+    ++  +  +V L
Sbjct: 264 QQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQP-PPLEPEEEEEVEL 322

Query: 188 SEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLD 238
             M  +      ++   +  +     +      +L  KLQ+ L+Q+E+QL+
Sbjct: 323 ELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLE 373



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 8/142 (5%)

Query: 2   QKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQVY 61
           ++++    +Q L+  QE L           P +EE  EL   P D  +EQEL    EQ  
Sbjct: 284 EQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQEL----EQQR 339

Query: 62  FSVDSFDIVKYELEKLPPVLNLQ-ELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE 120
             ++    ++ + E+    L LQ EL+    +L+QQQ  + ++   L L       ++ E
Sbjct: 340 QELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQE 399

Query: 121 ---RVTSLQTGLQLAAVICTNG 139
               +T +Q  LQL  V    G
Sbjct: 400 VQLELTPVQPELQLELVPAAGG 421


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 36.2 bits (82), Expect = 0.041
 Identities = 59/259 (22%), Positives = 107/259 (41%), Gaps = 25/259 (9%)

Query: 13   LKSPQESLSDLGAIESLRVPGKEEFRELRE-----QPSDPQAEQELINSIEQVYF-SVDS 66
            L+S ++    L  +E      + E  ELR      + S   AEQEL+++ E+V      +
Sbjct: 1667 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN 1726

Query: 67   FDIVKYELEKLPPVLNLQ-ELEAYRDKLKQQQAAVSKKVADLI-----LEKQPAYVKELE 120
              ++  + +    +  +Q E+E    + +  +    K + D       L+K+      LE
Sbjct: 1727 TSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1786

Query: 121  R--------VTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKR--QLLIGL 170
            R        V  LQ  L  A  +   G +      E   +   G + +++KR  + + GL
Sbjct: 1787 RMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGL 1846

Query: 171  LKSLRTIKTLQ-RTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNS--KLQ 227
             K  R +K L  +T+     +L  +D    +Q  ++  K  +        + L    KLQ
Sbjct: 1847 RKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQ 1906

Query: 228  DTLEQIEEQLDVALSKICK 246
              LE+ EE+ D+A S++ K
Sbjct: 1907 HELEEAEERADIAESQVNK 1925


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 36.2 bits (82), Expect = 0.041
 Identities = 59/259 (22%), Positives = 107/259 (41%), Gaps = 25/259 (9%)

Query: 13   LKSPQESLSDLGAIESLRVPGKEEFRELRE-----QPSDPQAEQELINSIEQVYF-SVDS 66
            L+S ++    L  +E      + E  ELR      + S   AEQEL+++ E+V      +
Sbjct: 1667 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN 1726

Query: 67   FDIVKYELEKLPPVLNLQ-ELEAYRDKLKQQQAAVSKKVADLI-----LEKQPAYVKELE 120
              ++  + +    +  +Q E+E    + +  +    K + D       L+K+      LE
Sbjct: 1727 TSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1786

Query: 121  R--------VTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKR--QLLIGL 170
            R        V  LQ  L  A  +   G +      E   +   G + +++KR  + + GL
Sbjct: 1787 RMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGL 1846

Query: 171  LKSLRTIKTLQ-RTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNS--KLQ 227
             K  R +K L  +T+     +L  +D    +Q  ++  K  +        + L    KLQ
Sbjct: 1847 RKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQ 1906

Query: 228  DTLEQIEEQLDVALSKICK 246
              LE+ EE+ D+A S++ K
Sbjct: 1907 HELEEAEERADIAESQVNK 1925


>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
          Length = 1710

 Score = 35.4 bits (80), Expect = 0.070
 Identities = 51/240 (21%), Positives = 93/240 (38%), Gaps = 46/240 (19%)

Query: 84   QELEAYRDKLKQQQA------AVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICT 137
            +EL + R  L Q++        + +K+ + +  K+  Y KE+E    L+  LQ   +   
Sbjct: 786  RELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELR 845

Query: 138  NGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKS-LRTIKTLQRTDVRL--------- 187
              + +LN   +    A   L   Q  R L  G+L + L   K ++    ++         
Sbjct: 846  TVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHE 905

Query: 188  --------SEMLEEEDYPGAIQLCLEC--------QKAASTFKHYSCISELNSKLQDTLE 231
                    + ML+EE       L LE         +K    F+    + E N  LQ T++
Sbjct: 906  EEKDLSHKNSMLQEE----IAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIK 961

Query: 232  QIEEQLDVALSK--------ICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHN 283
            Q EE L   +S+          +N  +N  +K++   +   + +  ++  H     AIH+
Sbjct: 962  QNEETLTQTISQYNGRLSVLTAENAMLN--SKLENEKQSKERLEAEVESYHSRLAAAIHD 1019


>gi|81295809 pericentrin [Homo sapiens]
          Length = 3336

 Score = 34.3 bits (77), Expect = 0.16
 Identities = 41/187 (21%), Positives = 78/187 (41%), Gaps = 27/187 (14%)

Query: 85  ELEAYRDKLKQQQAA-VSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNGRRHL 143
           ELEA R  L     A +    A+L  EK+ A  +  E + S +   Q  A++ +  +  L
Sbjct: 246 ELEALRLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRA--QELALLQSRQQHEL 303

Query: 144 NIAKEGFTQAS------LGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEEDYP 197
            + +E   +         G  A + K +L   + K+ + +KTL+            ED+ 
Sbjct: 304 ELLREQHAREKEEVVLRCGQEAAELKEKLQSEMEKNAQIVKTLK------------EDWE 351

Query: 198 GAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVAL------SKICKNFDIN 251
               LCLE  +   + KH S + +L ++ Q  L +   +L+          +  +N + +
Sbjct: 352 SEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQRAELEKIFQDKNQAERALRNLESH 411

Query: 252 HYTKVQQ 258
           H   +++
Sbjct: 412 HQAAIEK 418


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 33.9 bits (76), Expect = 0.20
 Identities = 44/207 (21%), Positives = 84/207 (40%), Gaps = 36/207 (17%)

Query: 92  KLKQQQAAVSKKVADLILEKQ------PAYVKELE----RVTSLQTGLQLAAVICTNGRR 141
           KL+QQ  A  K++  L +EK        +  +EL+    ++T+LQ  L   + +     +
Sbjct: 746 KLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEK 805

Query: 142 HLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEEDYPGAIQ 201
            L I KE F +AS   ++ QR  Q          T+  L + + + +             
Sbjct: 806 ELQILKEKFAEASEEAVSVQRSMQ---------ETVNKLHQKEEQFN------------M 844

Query: 202 LCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKNFDIN--HYTKVQQA 259
           L  + +K                + ++ L + +E+L+  +++I K    N    TK+   
Sbjct: 845 LSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDE 904

Query: 260 YRLLGKTQTAMDQLHMHFTQAIHNTVF 286
            RL    +  +++L +  T+A  N  F
Sbjct: 905 LRL---KERDVEELQLKLTKANENASF 928


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 33.9 bits (76), Expect = 0.20
 Identities = 44/207 (21%), Positives = 84/207 (40%), Gaps = 36/207 (17%)

Query: 92  KLKQQQAAVSKKVADLILEKQ------PAYVKELE----RVTSLQTGLQLAAVICTNGRR 141
           KL+QQ  A  K++  L +EK        +  +EL+    ++T+LQ  L   + +     +
Sbjct: 781 KLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEK 840

Query: 142 HLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEEDYPGAIQ 201
            L I KE F +AS   ++ QR  Q          T+  L + + + +             
Sbjct: 841 ELQILKEKFAEASEEAVSVQRSMQ---------ETVNKLHQKEEQFN------------M 879

Query: 202 LCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKNFDIN--HYTKVQQA 259
           L  + +K                + ++ L + +E+L+  +++I K    N    TK+   
Sbjct: 880 LSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDE 939

Query: 260 YRLLGKTQTAMDQLHMHFTQAIHNTVF 286
            RL    +  +++L +  T+A  N  F
Sbjct: 940 LRL---KERDVEELQLKLTKANENASF 963


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 33.9 bits (76), Expect = 0.20
 Identities = 52/273 (19%), Positives = 99/273 (36%), Gaps = 54/273 (19%)

Query: 36  EFRELREQPSDPQAEQELINSIEQVYFSVDSFDIV--KYELEKLPPVLNLQELEAYRDK- 92
           E +E +++  +    Q L + + +    +  F +   + E+EKL   L  +  E  +DK 
Sbjct: 195 ERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKK 254

Query: 93  ------------------LKQQQAAVSKKVADL---ILEKQPAYVKELERVTSLQTGLQL 131
                             + ++Q  + K++ +    + +K+P Y+K  E  +     L+ 
Sbjct: 255 RMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEA 314

Query: 132 AAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEML 191
           A     N ++H    K    +    +L+ ++ RQ                       E +
Sbjct: 315 AKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQ--------------------EFEERM 354

Query: 192 EEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKNFDIN 251
           EEE       L LE     +  K Y  + E  SK   TL Q  E+ +          D+ 
Sbjct: 355 EEESQSQGRDLTLE----ENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLE 410

Query: 252 HYTKVQ------QAYRLLGKTQTAMDQLHMHFT 278
              KV+      Q  R + + Q  +++L  + T
Sbjct: 411 ERKKVETEAKIKQKLREIEENQKRIEKLEEYIT 443


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 63/259 (24%), Positives = 108/259 (41%), Gaps = 24/259 (9%)

Query: 11   QGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQ--AEQELINSIEQV---YFSVD 65
            +G +  +E L+ +    +L     EE R   EQ    +  AEQEL++S E+V   +    
Sbjct: 1663 RGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNT 1722

Query: 66   SFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLI-----LEKQPAYVKELE 120
            S    K +LE     L  +  +A RD    ++ A  K + D       L+K+      LE
Sbjct: 1723 SLIHTKKKLETDLMQLQSEVEDASRDARNAEEKA-KKAITDAAMMAEELKKEQDTSAHLE 1781

Query: 121  R--------VTSLQTGLQLAAVICTNG-RRHLNIAKEGFTQASLGLLANQRKR-QLLIGL 170
            R        V  LQ  L  A  +   G ++ +   +    +    L   Q+K  + + GL
Sbjct: 1782 RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGL 1841

Query: 171  LKSLRTIKTLQ-RTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNS--KLQ 227
             K  R +K L  +++     +L  +D    +Q+ ++  K  +        + L    K Q
Sbjct: 1842 RKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQ 1901

Query: 228  DTLEQIEEQLDVALSKICK 246
              LE+ EE+ D+A S++ K
Sbjct: 1902 HELEEAEERADIAESQVNK 1920


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 57/259 (22%), Positives = 107/259 (41%), Gaps = 25/259 (9%)

Query: 13   LKSPQESLSDLGAIESLRVPGKEEFRELRE-----QPSDPQAEQELINSIEQVYF-SVDS 66
            L+S ++    L  +E      + E  ELR      + S   AEQEL+++ E+V      +
Sbjct: 1665 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN 1724

Query: 67   FDIVKYELEKLPPVLNLQ-ELEAYRDKLKQQQAAVSKKVADLI-----LEKQPAYVKELE 120
              ++  + +    +  +Q E+E    + +  +    K + D       L+K+      LE
Sbjct: 1725 TSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1784

Query: 121  R--------VTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQL--LIGL 170
            R        V  LQ  L  A  +   G +      E   +   G + +++KR +  + GL
Sbjct: 1785 RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGL 1844

Query: 171  LKSLRTIKTLQ-RTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNS--KLQ 227
             K  R +K L  +T+     +L  +D    +Q  ++  K  +          L+   ++Q
Sbjct: 1845 RKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQ 1904

Query: 228  DTLEQIEEQLDVALSKICK 246
              LE+ EE+ D+A S++ K
Sbjct: 1905 HELEEAEERADIAESQVNK 1923


>gi|62899065 centrosomal protein 72 kDa [Homo sapiens]
          Length = 647

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 41/175 (23%), Positives = 75/175 (42%), Gaps = 28/175 (16%)

Query: 98  AAVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGL 157
           A  SK +   + E+Q  + +E+  VT+    L        + R+HL+ + E         
Sbjct: 478 ALESKSLQSRLAEQQQQHAREMSEVTA---ELHHTHKELDDLRQHLDKSLE--------- 525

Query: 158 LANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYS 217
             N R + LL+ + K +++  T    +++++ +          +LC E  +     +HY 
Sbjct: 526 -ENSRLKSLLLSMKKEVKSADTAATLNLQIAGL-----QTSVKRLCGEIVELKQHLEHYD 579

Query: 218 CISELNSKLQD---TLEQIEEQLDVALSKICKNFDINHYTKVQQ---AYRLLGKT 266
            I EL   LQ+   +L    E L   LS++       H  +V+Q   +Y+ L KT
Sbjct: 580 KIQELTQMLQESHSSLVSTNEHLLQELSQV----RAQHRAEVEQMHWSYQELKKT 630


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 33.1 bits (74), Expect = 0.35
 Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 20/116 (17%)

Query: 35   EEFRELREQPSD--PQAEQELINSIEQVYFSVDSFDIVKYELE--KLPPVLNLQELEAYR 90
            + F+EL E+  +   +AE++++    QVY      +  K ELE   L      +EL+A  
Sbjct: 1567 QHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALE 1626

Query: 91   DKLK---------------QQQAAVSKKVADLILEKQPAYVKELE-RVTSLQTGLQ 130
            D+L+               Q+ AA+ K++   + EK+  Y K  E  ++ L T LQ
Sbjct: 1627 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQ 1682


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 32.7 bits (73), Expect = 0.45
 Identities = 45/192 (23%), Positives = 88/192 (45%), Gaps = 15/192 (7%)

Query: 3   KIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQVYF 62
           K K+L T   +K  + S  + G  +      +EE + L+   +    E+E      +VY 
Sbjct: 376 KTKALQTVIEMKDSKISSMERGLRDL-----EEEIQMLKSNGALSTEEREEEMKQMEVYR 430

Query: 63  SVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELERV 122
           S   F  +K ++E+L   L+ +E  A  ++LK++ A +  ++  +   KQ    K+ E +
Sbjct: 431 SHSKF--MKNKVEQLKEELSSKE--AQWEELKKKAAGLQAEIGQV---KQELSRKDTE-L 482

Query: 123 TSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQR 182
            +LQT L+      ++ ++H+ + KE  T         Q +   L   L+   T+  L +
Sbjct: 483 LALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETM--LNK 540

Query: 183 TDVRLSEMLEEE 194
              ++ +M EE+
Sbjct: 541 KTKQIQDMAEEK 552


>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
           b [Homo sapiens]
          Length = 882

 Score = 32.3 bits (72), Expect = 0.59
 Identities = 58/252 (23%), Positives = 104/252 (41%), Gaps = 50/252 (19%)

Query: 29  LRVPGKEEFRELREQPSDPQAEQELINSIEQVYFSVDSFDIVKYELEKLPPVLNLQELEA 88
           L++  KE     +EQ S+ +  +EL   + +    +++ D  K +L+K     ++ ++  
Sbjct: 383 LQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDM-KMND 441

Query: 89  YRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNGRRHLNIAKE 148
             D++K Q              ++   +K       L+  LQ A  +  + R  L  +KE
Sbjct: 442 MLDRIKHQ-------------HREQGSIK-----CKLEEDLQEATKLLEDKREQLKKSKE 483

Query: 149 GFTQASLGLLANQRKRQLLIGLLKSLR-TIKTLQRTDVRLSEMLEEEDYPGAIQL-CLEC 206
                           +L+ G L++LR   K   +T    S  LEEE+     +L C   
Sbjct: 484 --------------HEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCST 529

Query: 207 QKAASTFKH---YSCISELNSKL---QDTLEQIEEQLDVALSKICKNFDINHY---TKVQ 257
           Q  +S  K+      I +LN ++   +++L  ++ QLD AL K        HY   T  +
Sbjct: 530 QLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQK------EKHYLQTTITK 583

Query: 258 QAYRLLGKTQTA 269
           +AY  L +   A
Sbjct: 584 EAYDALSRKSAA 595


>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
           a [Homo sapiens]
          Length = 1007

 Score = 32.3 bits (72), Expect = 0.59
 Identities = 58/252 (23%), Positives = 104/252 (41%), Gaps = 50/252 (19%)

Query: 29  LRVPGKEEFRELREQPSDPQAEQELINSIEQVYFSVDSFDIVKYELEKLPPVLNLQELEA 88
           L++  KE     +EQ S+ +  +EL   + +    +++ D  K +L+K     ++ ++  
Sbjct: 528 LQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDM-KMND 586

Query: 89  YRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNGRRHLNIAKE 148
             D++K Q              ++   +K       L+  LQ A  +  + R  L  +KE
Sbjct: 587 MLDRIKHQ-------------HREQGSIK-----CKLEEDLQEATKLLEDKREQLKKSKE 628

Query: 149 GFTQASLGLLANQRKRQLLIGLLKSLR-TIKTLQRTDVRLSEMLEEEDYPGAIQL-CLEC 206
                           +L+ G L++LR   K   +T    S  LEEE+     +L C   
Sbjct: 629 --------------HEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCST 674

Query: 207 QKAASTFKH---YSCISELNSKL---QDTLEQIEEQLDVALSKICKNFDINHY---TKVQ 257
           Q  +S  K+      I +LN ++   +++L  ++ QLD AL K        HY   T  +
Sbjct: 675 QLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQK------EKHYLQTTITK 728

Query: 258 QAYRLLGKTQTA 269
           +AY  L +   A
Sbjct: 729 EAYDALSRKSAA 740


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 32.3 bits (72), Expect = 0.59
 Identities = 52/250 (20%), Positives = 111/250 (44%), Gaps = 38/250 (15%)

Query: 34   KEEFRELREQPSDPQAEQELINSIE-----QVYFSVDSFDIVKYELEKLPPVLNLQ---- 84
            K++ +EL  + S+ +   + ++  +     +V   +  + +  +E EK    L L     
Sbjct: 2661 KDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQ 2720

Query: 85   ---ELEAYRDKLKQQQAAVS--KKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNG 139
               E++ YR+KL  ++  +S  K   DL+   +      L+  T +   L+   +   + 
Sbjct: 2721 YEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKM---DN 2777

Query: 140  RRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEEDYPGA 199
             +++N  K+   +A       Q K +LLI   K L   K + + ++   +  +E+   G 
Sbjct: 2778 LKYVNQLKKENERA-------QGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGT 2830

Query: 200  IQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKNFDINHYTKVQQA 259
            + +  +  +  +  K          +L++TLE+  ++ D  L K C +  I+H  K+++A
Sbjct: 2831 V-MDTKVDELTTEIK----------ELKETLEEKTKEADEYLDKYC-SLLISH-EKLEKA 2877

Query: 260  YRLLGKTQTA 269
              +L +TQ A
Sbjct: 2878 KEML-ETQVA 2886



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 44/174 (25%), Positives = 72/174 (41%), Gaps = 35/174 (20%)

Query: 33   GKEEFRELREQPSDPQAEQE--LINSIEQVYFSVDSFDIVKYELEKLPPVLNLQELEAYR 90
            G +E  +  EQ  DP  E+E  L NSIE++   +++      E ++L  +  L+E E + 
Sbjct: 2277 GDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEAD-----EKKQLCVLQQLKESEHHA 2331

Query: 91   DKLKQQQAAVSKKVADLILEKQPAYVKELERVTSL-QTGLQLAAVICTNGRRHLNIAK-- 147
            D LK +                   V+ LER   + +T  + AA+   N +  +   K  
Sbjct: 2332 DLLKGR-------------------VENLERELEIARTNQEHAALEAENSKGEVETLKAK 2372

Query: 148  -EGFTQASLGL-----LANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEED 195
             EG TQ+  GL          K  L   L K    I  L+  +     +L+E++
Sbjct: 2373 IEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKE 2426


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 32.0 bits (71), Expect = 0.77
 Identities = 50/243 (20%), Positives = 102/243 (41%), Gaps = 31/243 (12%)

Query: 35   EEFRELREQPSDPQAEQELINSIEQVYFSVDSFDIVKYELEKLPPVLNLQ--------EL 86
            ++ +E R Q  +P  E    +SIE ++   +  +IVK   +K   +  L+        E+
Sbjct: 997  KQVKEYRIQ--EPNRENSFHSSIEAIW--EECKEIVKASSKKSHQIEELEQQIEKLQAEV 1052

Query: 87   EAYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNGRRHLNIA 146
            + Y+D+  + +    K   DL+ EK+         +  L+  LQ   V      +H+   
Sbjct: 1053 KGYKDENNRLKEKEHKNQDDLLKEKETL-------IQQLKEELQEKNVTLDVQIQHVVEG 1105

Query: 147  KEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEEDYPGAIQLCLEC 206
            K   ++ + G+   + K       +K L TI   Q+ +   S  L E+D      + L+ 
Sbjct: 1106 KRALSELTQGVTCYKAK-------IKELETILETQKVECSHSAKL-EQDILEKESIILKL 1157

Query: 207  QKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKNF-DINHYTKVQQAYRLLGK 265
            ++    F+ +   S  N+K    L   E +L   ++++  N  D+ H  ++++      +
Sbjct: 1158 ERNLKEFQEHLQDSVKNTK---DLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNR 1214

Query: 266  TQT 268
             +T
Sbjct: 1215 QET 1217


>gi|27436948 lamin A/C isoform 3 [Homo sapiens]
          Length = 634

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 47/207 (22%), Positives = 84/207 (40%), Gaps = 27/207 (13%)

Query: 85  ELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNGRRHLN 144
           EL   R++ K+ +A  +KK  DLI  +  A +K+LE   +L    + A     + +R L 
Sbjct: 105 ELSKVREEFKELKARNTKKEGDLIAAQ--ARLKDLE---ALLNSKEAALSTALSEKRTL- 158

Query: 145 IAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDV--RLSEMLEEEDYPGAIQL 202
              EG      G +A   K +  +G  K     + L+R D   RL  M EE D+    Q 
Sbjct: 159 ---EGELHDLRGQVA---KLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDF----QK 208

Query: 203 CLECQKAASTFKHYSC---------ISELNSKLQDTLEQIEEQLDVALSKICKNFDINHY 253
            +  ++   T + +             E  S+L D L+++  Q +  + +  K  +  + 
Sbjct: 209 NIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYS 268

Query: 254 TKVQQAYRLLGKTQTAMDQLHMHFTQA 280
            K+  A +   +    +   H    Q+
Sbjct: 269 AKLDNARQSAERNSNLVGAAHEELQQS 295


>gi|5031875 lamin A/C isoform 2 [Homo sapiens]
          Length = 572

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 47/207 (22%), Positives = 84/207 (40%), Gaps = 27/207 (13%)

Query: 85  ELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNGRRHLN 144
           EL   R++ K+ +A  +KK  DLI  +  A +K+LE   +L    + A     + +R L 
Sbjct: 105 ELSKVREEFKELKARNTKKEGDLIAAQ--ARLKDLE---ALLNSKEAALSTALSEKRTL- 158

Query: 145 IAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDV--RLSEMLEEEDYPGAIQL 202
              EG      G +A   K +  +G  K     + L+R D   RL  M EE D+    Q 
Sbjct: 159 ---EGELHDLRGQVA---KLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDF----QK 208

Query: 203 CLECQKAASTFKHYSC---------ISELNSKLQDTLEQIEEQLDVALSKICKNFDINHY 253
            +  ++   T + +             E  S+L D L+++  Q +  + +  K  +  + 
Sbjct: 209 NIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYS 268

Query: 254 TKVQQAYRLLGKTQTAMDQLHMHFTQA 280
            K+  A +   +    +   H    Q+
Sbjct: 269 AKLDNARQSAERNSNLVGAAHEELQQS 295


>gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens]
          Length = 664

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 47/207 (22%), Positives = 84/207 (40%), Gaps = 27/207 (13%)

Query: 85  ELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNGRRHLN 144
           EL   R++ K+ +A  +KK  DLI  +  A +K+LE   +L    + A     + +R L 
Sbjct: 105 ELSKVREEFKELKARNTKKEGDLIAAQ--ARLKDLE---ALLNSKEAALSTALSEKRTL- 158

Query: 145 IAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDV--RLSEMLEEEDYPGAIQL 202
              EG      G +A   K +  +G  K     + L+R D   RL  M EE D+    Q 
Sbjct: 159 ---EGELHDLRGQVA---KLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDF----QK 208

Query: 203 CLECQKAASTFKHYSC---------ISELNSKLQDTLEQIEEQLDVALSKICKNFDINHY 253
            +  ++   T + +             E  S+L D L+++  Q +  + +  K  +  + 
Sbjct: 209 NIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYS 268

Query: 254 TKVQQAYRLLGKTQTAMDQLHMHFTQA 280
            K+  A +   +    +   H    Q+
Sbjct: 269 AKLDNARQSAERNSNLVGAAHEELQQS 295


>gi|4885075 atonal homolog 1 [Homo sapiens]
          Length = 354

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 4/114 (3%)

Query: 79  PVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTN 138
           P L   E  A RD++  +   V +        K P  VK  E++  L+ G+ +  + C+ 
Sbjct: 85  PELGASEAAAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKLKGGVVVDELGCSR 144

Query: 139 GRRHLNIAKEGFTQASLGLLANQRKRQLLIGL---LKSLRTIKTLQRTDVRLSE 189
            R   +    G  Q    L AN R+R+ + GL      LR +      D +LS+
Sbjct: 145 QRAPSSKQVNG-VQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSK 197


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 45/211 (21%), Positives = 94/211 (44%), Gaps = 33/211 (15%)

Query: 34  KEEFRELREQPSDPQAEQELINSIEQVYFSVDSFDIVKYELEKLPPVLNLQELEAYRDKL 93
           KE F E      D +A      +I  +   ++   +VK EL+K        ++++ +D++
Sbjct: 186 KERFEEEARLRDDTEA------AIRALRKDIEEASLVKVELDK--------KVQSLQDEV 231

Query: 94  KQQQAAVSKKVADLILEKQPAYVKELERVTSLQTGLQLA-----AVICTNGRRHLNIAKE 148
              ++   ++VADL+ + Q +++  +ER   L+T +  A     + + ++  ++++ A+E
Sbjct: 232 AFLRSNHEEEVADLLAQIQASHIT-VERKDYLKTDISTALKEIRSQLESHSDQNMHQAEE 290

Query: 149 GFT--QASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEEDYPGAIQLCLEC 206
            F    A L   A Q K  +     +     + LQ   + L  +   ++        LE 
Sbjct: 291 WFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKE-------SLER 343

Query: 207 QKAASTFKHYSCISELNSKLQDTLEQIEEQL 237
           Q +    +H   +S      QDT++Q+E +L
Sbjct: 344 QLSDIEERHNHDLSSY----QDTIQQLENEL 370


>gi|195976782 Paf1/RNA polymerase II complex component [Homo
           sapiens]
          Length = 710

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 7/86 (8%)

Query: 33  GKEEFRELREQPSDPQAEQELINSIEQVYFSVDSFDIVKYELEKLPPVLNLQELEAYRDK 92
           G EE R   EQ ++ + EQEL N IE+        +++K   E    +   ++ E    K
Sbjct: 188 GDEEDRARLEQMTEKEREQELFNRIEK-------REVLKRRFEIKKKLKTAKKKEKKEKK 240

Query: 93  LKQQQAAVSKKVADLILEKQPAYVKE 118
            KQ++    KK+  +   +  ++ KE
Sbjct: 241 KKQEEEQEKKKLTQIQESQVTSHNKE 266


>gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Homo
            sapiens]
          Length = 3549

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 41/162 (25%), Positives = 62/162 (38%), Gaps = 9/162 (5%)

Query: 151  TQASLGLLANQRKRQLLIGLLKS--LRTIKTLQRTDVRLSEMLEEEDYPGAIQLCLECQK 208
            T  SL    NQ+       ++K   L T+K+L+ +  R  E  + +  PG I+  +EC +
Sbjct: 1844 TLNSLSQAVNQKTVTKTEEIIKGNMLATLKSLKESSHRWKESKQPDAIPGDIEKAIECLE 1903

Query: 209  AASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKNFDINHYTKVQQAYRLLGKTQT 268
             A+  K      EL   L+D LE     L  A  +  K        K      + G +  
Sbjct: 1904 KATNTKTEILKKEL---LKDDLETSLRSLKEA-QRSFKEVHKEGVIKKDAKAVMAGSSGE 1959

Query: 269  AMDQLHMHFTQAIHNTVFQVVLGYVELCA---GNTDTKFQKL 307
                +H    Q   N++ Q   G  E  A   G  DT  Q +
Sbjct: 1960 QKTDIHQVAVQRNKNSLLQPKPGPFEPAAKWQGGADTLSQTM 2001


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,341,847
Number of Sequences: 37866
Number of extensions: 468751
Number of successful extensions: 2086
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 76
Number of HSP's that attempted gapping in prelim test: 2026
Number of HSP's gapped (non-prelim): 137
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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