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Search of human proteins with 33188437
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
(1091 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] 2194 0.0
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] 2168 0.0
gi|41281898 StAR-related lipid transfer (START) domain containin... 1102 0.0
gi|41281907 StAR-related lipid transfer (START) domain containin... 1099 0.0
gi|16445031 StAR-related lipid transfer (START) domain containin... 999 0.0
gi|215820652 StAR-related lipid transfer (START) domain containi... 653 0.0
gi|215820650 StAR-related lipid transfer (START) domain containi... 653 0.0
gi|31543659 StAR-related lipid transfer (START) domain containin... 653 0.0
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] 99 2e-20
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 92 3e-18
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 92 3e-18
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 92 3e-18
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom... 88 4e-17
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom... 88 4e-17
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H... 88 4e-17
gi|54860079 nadrin isoform 1 [Homo sapiens] 88 4e-17
gi|54860105 nadrin isoform 2 [Homo sapiens] 88 4e-17
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 85 4e-16
gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap... 84 9e-16
gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap... 84 9e-16
gi|40255080 hypothetical protein LOC158763 [Homo sapiens] 83 1e-15
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 83 1e-15
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 83 2e-15
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 82 3e-15
gi|5803145 ralA binding protein 1 [Homo sapiens] 82 3e-15
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 82 3e-15
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 82 3e-15
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 82 4e-15
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 79 2e-14
gi|89886350 Rho GTPase activating protein 11B [Homo sapiens] 79 2e-14
>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
Length = 1091
Score = 2194 bits (5686), Expect = 0.0
Identities = 1091/1091 (100%), Positives = 1091/1091 (100%)
Query: 1 MCRKKPDTMILTQIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIE 60
MCRKKPDTMILTQIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIE
Sbjct: 1 MCRKKPDTMILTQIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIE 60
Query: 61 ALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFS 120
ALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFS
Sbjct: 61 ALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFS 120
Query: 121 PKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPR 180
PKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPR
Sbjct: 121 PKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPR 180
Query: 181 TNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLK 240
TNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLK
Sbjct: 181 TNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLK 240
Query: 241 SSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNS 300
SSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNS
Sbjct: 241 SSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNS 300
Query: 301 TQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKN 360
TQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKN
Sbjct: 301 TQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKN 360
Query: 361 RESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSS 420
RESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSS
Sbjct: 361 RESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSS 420
Query: 421 DSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQ 480
DSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQ
Sbjct: 421 DSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQ 480
Query: 481 RIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEP 540
RIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEP
Sbjct: 481 RIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEP 540
Query: 541 SEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLL 600
SEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLL
Sbjct: 541 SEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLL 600
Query: 601 KLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQ 660
KLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQ
Sbjct: 601 KLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQ 660
Query: 661 AMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDL 720
AMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDL
Sbjct: 661 AMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDL 720
Query: 721 PEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKE 780
PEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKE
Sbjct: 721 PEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKE 780
Query: 781 NQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMI 840
NQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMI
Sbjct: 781 NQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMI 840
Query: 841 AECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVK 900
AECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVK
Sbjct: 841 AECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVK 900
Query: 901 EKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLL 960
EKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLL
Sbjct: 901 EKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLL 960
Query: 961 DSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVV 1020
DSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVV
Sbjct: 961 DSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVV 1020
Query: 1021 GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSN 1080
GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSN
Sbjct: 1021 GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSN 1080
Query: 1081 QNTETKDTKSR 1091
QNTETKDTKSR
Sbjct: 1081 QNTETKDTKSR 1091
>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
Length = 1528
Score = 2168 bits (5618), Expect = 0.0
Identities = 1078/1079 (99%), Positives = 1079/1079 (100%)
Query: 13 QIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC 72
+IEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC
Sbjct: 450 EIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC 509
Query: 73 AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD 132
AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD
Sbjct: 510 AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD 569
Query: 133 SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSN 192
SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSN
Sbjct: 570 SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSN 629
Query: 193 LAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPSK 252
LAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPSK
Sbjct: 630 LAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPSK 689
Query: 253 LGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSSSSQSET 312
LGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSSSSQSET
Sbjct: 690 LGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSSSSQSET 749
Query: 313 SSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDTVFYI 372
SSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDTVFYI
Sbjct: 750 SSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDTVFYI 809
Query: 373 PEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSS 432
PEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSS
Sbjct: 810 PEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSS 869
Query: 433 SSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSD 492
SSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSD
Sbjct: 870 SSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSD 929
Query: 493 EGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEPSEIPERRDSGVG 552
EGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEPSEIPERRDSGVG
Sbjct: 930 EGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEPSEIPERRDSGVG 989
Query: 553 ASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPS 612
ASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPS
Sbjct: 990 ASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPS 1049
Query: 613 NKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQ 672
NKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQ
Sbjct: 1050 NKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQ 1109
Query: 673 VGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSET 732
VGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSET
Sbjct: 1110 VGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSET 1169
Query: 733 FLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCL 792
FLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCL
Sbjct: 1170 FLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCL 1229
Query: 793 APSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE 852
APSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE
Sbjct: 1230 APSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE 1289
Query: 853 MSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTS 912
MSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTS
Sbjct: 1290 MSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTS 1349
Query: 913 EQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQT 972
EQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQT
Sbjct: 1350 EQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQT 1409
Query: 973 EIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSRYL 1032
EIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSRYL
Sbjct: 1410 EIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSRYL 1469
Query: 1033 IEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR 1091
IEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR
Sbjct: 1470 IEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR 1528
>gi|41281898 StAR-related lipid transfer (START) domain containing 13
isoform alpha [Homo sapiens]
Length = 1113
Score = 1102 bits (2849), Expect = 0.0
Identities = 608/1105 (55%), Positives = 779/1105 (70%), Gaps = 53/1105 (4%)
Query: 1 MCRKKPDTMILTQIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIE 60
+ R + T I +IEAKEACDWLRA GFPQYAQLYED FPI+I VK +HDFL++D +E
Sbjct: 45 LARHQLVTKIQQEIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVKNDHDFLEKDLVE 104
Query: 61 ALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFS 120
LCRRLNTLNKCA MKL+++ RK+ DDSDE++ C IS KWTFQR S+RWSR+++
Sbjct: 105 PLCRRLNTLNKCASMKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLL 163
Query: 121 PKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPR 180
P+ D GSP + ++ S L DLSE EV S+ S SS GS S + P +
Sbjct: 164 PRGDR-NGSPGGTGMRNTTSSESVLTDLSE-PEVCSIHSESSGGS-DSRSQPGQ------ 214
Query: 181 TNSVISVCSSSNLAGNDDSF--GSLPSP-KELSSFSFSMKGHEKTAKSKTRSLLKRMESL 237
C + N D SLP P +++ + F K +EK +++ +S LKRME+L
Sbjct: 215 -------CCTDNPVMLDAPLVSSSLPQPPRDVLNHPFHPK-NEKPTRARAKSFLKRMETL 266
Query: 238 KLKSSHHSKHKAPSKLG-LIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVR-KR 295
+ K +H +HK + G L+ISGP+LQ+ + E K + C++I NG+ N P ++
Sbjct: 267 RGKGAH-GRHKGSGRTGGLVISGPMLQQ--EPESFKAMQCIQIP--NGDLQNSPPPACRK 321
Query: 296 SVSNSTQTSSSSSQSE-TSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVV 354
+ S ++S SS SE +SS VSTP + R NKR GMYLE D + +
Sbjct: 322 GLPCSGKSSGESSPSEHSSSGVSTPC--LKERKCHEANKRGGMYLEDLDVLAGTALPDAG 379
Query: 355 EQNFKNRESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISL 414
+Q+ + E+ V +IP+DHKPGTFPKAL+ S SP+ ++ VNWRTGS ISL
Sbjct: 380 DQSRMHEFHSQENLVVHIPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGS------ISL 433
Query: 415 RRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILY 474
RE + + R +S +SR+SIYDNVPGS LY+S+GDL DLE +D+FP LDDIL
Sbjct: 434 GREQVPGAREP--RLMASCHRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQ 491
Query: 475 HVKGMQRIVNQWSEKFSDEGDSDSAL---DSVSPCPSSPKQIHLD-----VDNDRTTPSD 526
HV G+Q +V+ WS+ E + L +S PS P QI LD V RTTPSD
Sbjct: 492 HVNGLQEVVDDWSKDVLPELQTHDTLVGEPGLSTFPS-PNQITLDFEGNSVSEGRTTPSD 550
Query: 527 LDSTGNSLNEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQ 586
++ SLNE E P + +RRDSGVGASLTR NR RLRW+SFQ SH+P S I+ Q
Sbjct: 551 VERDVTSLNESEPPG-VRDRRDSGVGASLTRPNR-RLRWNSFQLSHQPRPAPASPHISSQ 608
Query: 587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 646
+ +Q++LLQ++SLL+LTA++EK++ SNKHG++W+VPKFMKR+KVPDYKD++VFGVPL V+
Sbjct: 609 TASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVH 668
Query: 647 VQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSA 706
VQRTGQPLPQSIQQA+RYLR++CLDQVGLFRKSGVKSRI ALRQMNE + VNYE QSA
Sbjct: 669 VQRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSA 728
Query: 707 YDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQT 766
YDVADM+KQ+FRDLPEPL TNKLSETFL IYQYV K+QRLQA++AAI+LL DENREVLQT
Sbjct: 729 YDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQT 788
Query: 767 LLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDL 826
LL FL+DV V+ENQMTP NLAVCLAPSLFHLN LK+E SSPRV+Q+K + GKPDQKDL
Sbjct: 789 LLCFLNDVVNLVEENQMTPMNLAVCLAPSLFHLNLLKKE-SSPRVIQKKYATGKPDQKDL 847
Query: 827 NENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGHLGNDDSADYQ 885
NENLAA QGLAHMI EC +LF+VP E+ ++ RNSY E E+ TLE LG + A +
Sbjct: 848 NENLAAAQGLAHMIMECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFH 907
Query: 886 HFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEIL 945
+L + GL KE KEKFKGWV+ S+++ +L++KKV +G PL+LW++ +EV A P +L
Sbjct: 908 TYLNHLIQGLQKEAKEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVL 967
Query: 946 KRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGAC 1005
R+L+E+HLWD D + KV+E LD QTEIYQYV NSMAPHP+RD+VVLRTW+T+LPKG C
Sbjct: 968 NRVLRERHLWDEDFVQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMC 1027
Query: 1006 ALLLTSVDHDRAPVV-GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFG 1064
L+ SV+H+ A ++ GVR V+ S+YLIEPCG GKS+LT++CR+DL+GH PEWY+K FG
Sbjct: 1028 TLVSLSVEHEEAQLLGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFG 1087
Query: 1065 HLCAAEVVKIRDSFSNQNTETKDTK 1089
HLCAAEV +IR+SF E +TK
Sbjct: 1088 HLCAAEVARIRNSFQPLIAEGPETK 1112
>gi|41281907 StAR-related lipid transfer (START) domain containing 13
isoform beta [Homo sapiens]
Length = 1105
Score = 1099 bits (2843), Expect = 0.0
Identities = 605/1093 (55%), Positives = 774/1093 (70%), Gaps = 53/1093 (4%)
Query: 13 QIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC 72
+IEAKEACDWLRA GFPQYAQLYED FPI+I VK +HDFL++D +E LCRRLNTLNKC
Sbjct: 49 EIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVKNDHDFLEKDLVEPLCRRLNTLNKC 108
Query: 73 AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD 132
A MKL+++ RK+ DDSDE++ C IS KWTFQR S+RWSR+++ P+ D GSP
Sbjct: 109 ASMKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLLPRGDR-NGSPGG 166
Query: 133 SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSN 192
+ ++ S L DLSE EV S+ S SS GS S + P + C + N
Sbjct: 167 TGMRNTTSSESVLTDLSE-PEVCSIHSESSGGS-DSRSQPGQ-------------CCTDN 211
Query: 193 LAGNDDSF--GSLPSP-KELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKA 249
D SLP P +++ + F K +EK +++ +S LKRME+L+ K +H +HK
Sbjct: 212 PVMLDAPLVSSSLPQPPRDVLNHPFHPK-NEKPTRARAKSFLKRMETLRGKGAH-GRHKG 269
Query: 250 PSKLG-LIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVR-KRSVSNSTQTSSSS 307
+ G L+ISGP+LQ+ + E K + C++I NG+ N P ++ + S ++S S
Sbjct: 270 SGRTGGLVISGPMLQQ--EPESFKAMQCIQIP--NGDLQNSPPPACRKGLPCSGKSSGES 325
Query: 308 SQSE-TSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPE 366
S SE +SS VSTP + R NKR GMYLE D + + +Q+ + E
Sbjct: 326 SPSEHSSSGVSTPC--LKERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEFHSQE 383
Query: 367 DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKEL 426
+ V +IP+DHKPGTFPKAL+ S SP+ ++ VNWRTGS ISL RE + +
Sbjct: 384 NLVVHIPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGS------ISLGREQVPGAREP- 436
Query: 427 KRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQW 486
R +S +SR+SIYDNVPGS LY+S+GDL DLE +D+FP LDDIL HV G+Q +V+ W
Sbjct: 437 -RLMASCHRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQHVNGLQEVVDDW 495
Query: 487 SEKFSDEGDSDSAL---DSVSPCPSSPKQIHLD-----VDNDRTTPSDLDSTGNSLNEPE 538
S+ E + L +S PS P QI LD V RTTPSD++ SLNE E
Sbjct: 496 SKDVLPELQTHDTLVGEPGLSTFPS-PNQITLDFEGNSVSEGRTTPSDVERDVTSLNESE 554
Query: 539 EPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYS 598
P + +RRDSGVGASLTR NR RLRW+SFQ SH+P S I+ Q+ +Q++LLQ++S
Sbjct: 555 PPG-VRDRRDSGVGASLTRPNR-RLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFS 612
Query: 599 LLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSI 658
LL+LTA++EK++ SNKHG++W+VPKFMKR+KVPDYKD++VFGVPL V+VQRTGQPLPQSI
Sbjct: 613 LLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSI 672
Query: 659 QQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFR 718
QQA+RYLR++CLDQVGLFRKSGVKSRI ALRQMNE + VNYE QSAYDVADM+KQ+FR
Sbjct: 673 QQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQFFR 732
Query: 719 DLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAV 778
DLPEPL TNKLSETFL IYQYV K+QRLQA++AAI+LL DENREVLQTLL FL+DV V
Sbjct: 733 DLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLV 792
Query: 779 KENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAH 838
+ENQMTP NLAVCLAPSLFHLN LK+E SSPRV+Q+K + GKPDQKDLNENLAA QGLAH
Sbjct: 793 EENQMTPMNLAVCLAPSLFHLNLLKKE-SSPRVIQKKYATGKPDQKDLNENLAAAQGLAH 851
Query: 839 MIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFK 897
MI EC +LF+VP E+ ++ RNSY E E+ TLE LG + A + +L + GL K
Sbjct: 852 MIMECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLIQGLQK 911
Query: 898 EVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDV 957
E KEKFKGWV+ S+++ +L++KKV +G PL+LW++ +EV A P +L R+L+E+HLWD
Sbjct: 912 EAKEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERHLWDE 971
Query: 958 DLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRA 1017
D + KV+E LD QTEIYQYV NSMAPHP+RD+VVLRTW+T+LPKG C L+ SV+H+ A
Sbjct: 972 DFVQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVEHEEA 1031
Query: 1018 PVV-GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRD 1076
++ GVR V+ S+YLIEPCG GKS+LT++CR+DL+GH PEWY+K FGHLCAAEV +IR+
Sbjct: 1032 QLLGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVARIRN 1091
Query: 1077 SFSNQNTETKDTK 1089
SF E +TK
Sbjct: 1092 SFQPLIAEGPETK 1104
>gi|16445031 StAR-related lipid transfer (START) domain containing 13
isoform gamma [Homo sapiens]
Length = 995
Score = 999 bits (2583), Expect = 0.0
Identities = 558/1031 (54%), Positives = 721/1031 (69%), Gaps = 53/1031 (5%)
Query: 75 MKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDDSH 134
MKL+++ RK+ DDSDE++ C IS KWTFQR S+RWSR+++ P+ D GSP +
Sbjct: 1 MKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLLPRGDR-NGSPGGTG 58
Query: 135 PKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSNLA 194
++ S L DLSE EV S+ S SS GS S + P + C + N
Sbjct: 59 MRNTTSSESVLTDLSE-PEVCSIHSESSGGS-DSRSQPGQ-------------CCTDNPV 103
Query: 195 GNDDSF--GSLPSP-KELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPS 251
D SLP P +++ + F K +EK +++ +S LKRME+L+ K +H +HK
Sbjct: 104 MLDAPLVSSSLPQPPRDVLNHPFHPK-NEKPTRARAKSFLKRMETLRGKGAH-GRHKGSG 161
Query: 252 KLG-LIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVR-KRSVSNSTQTSSSSSQ 309
+ G L+ISGP+LQ+ + E K + C++I NG+ N P ++ + S ++S SS
Sbjct: 162 RTGGLVISGPMLQQ--EPESFKAMQCIQIP--NGDLQNSPPPACRKGLPCSGKSSGESSP 217
Query: 310 SE-TSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDT 368
SE +SS VSTP + R NKR GMYLE D + + +Q+ + E+
Sbjct: 218 SEHSSSGVSTPC--LKERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEFHSQENL 275
Query: 369 VFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKR 428
V +IP+DHKPGTFPKAL+ S SP+ ++ VNWRTGS ISL RE + + R
Sbjct: 276 VVHIPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGS------ISLGREQVPGAREP--R 327
Query: 429 RNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSE 488
+S +SR+SIYDNVPGS LY+S+GDL DLE +D+FP LDDIL HV G+Q +V+ WS+
Sbjct: 328 LMASCHRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQHVNGLQEVVDDWSK 387
Query: 489 KFSDEGDSDSAL---DSVSPCPSSPKQIHLD-----VDNDRTTPSDLDSTGNSLNEPEEP 540
E + L +S PS P QI LD V RTTPSD++ SLNE E P
Sbjct: 388 DVLPELQTHDTLVGEPGLSTFPS-PNQITLDFEGNSVSEGRTTPSDVERDVTSLNESEPP 446
Query: 541 SEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLL 600
+ +RRDSGVGASLTR NR RLRW+SFQ SH+P S I+ Q+ +Q++LLQ++SLL
Sbjct: 447 G-VRDRRDSGVGASLTRPNR-RLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLL 504
Query: 601 KLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQ 660
+LTA++EK++ SNKHG++W+VPKFMKR+KVPDYKD++VFGVPL V+VQRTGQPLPQSIQQ
Sbjct: 505 RLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQ 564
Query: 661 AMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDL 720
A+RYLR++CLDQVGLFRKSGVKSRI ALRQMNE + VNYE QSAYDVADM+KQ+FRDL
Sbjct: 565 ALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQFFRDL 624
Query: 721 PEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKE 780
PEPL TNKLSETFL IYQYV K+QRLQA++AAI+LL DENREVLQTLL FL+DV V+E
Sbjct: 625 PEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEE 684
Query: 781 NQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMI 840
NQMTP NLAVCLAPSLFHLN LK+E SSPRV+Q+K + GKPDQKDLNENLAA QGLAHMI
Sbjct: 685 NQMTPMNLAVCLAPSLFHLNLLKKE-SSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMI 743
Query: 841 AECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEV 899
EC +LF+VP E+ ++ RNSY E E+ TLE LG + A + +L + GL KE
Sbjct: 744 MECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLIQGLQKEA 803
Query: 900 KEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDL 959
KEKFKGWV+ S+++ +L++KKV +G PL+LW++ +EV A P +L R+L+E+HLWD D
Sbjct: 804 KEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERHLWDEDF 863
Query: 960 LDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPV 1019
+ KV+E LD QTEIYQYV NSMAPHP+RD+VVLRTW+T+LPKG C L+ SV+H+ A +
Sbjct: 864 VQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVEHEEAQL 923
Query: 1020 V-GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSF 1078
+ GVR V+ S+YLIEPCG GKS+LT++CR+DL+GH PEWY+K FGHLCAAEV +IR+SF
Sbjct: 924 LGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVARIRNSF 983
Query: 1079 SNQNTETKDTK 1089
E +TK
Sbjct: 984 QPLIAEGPETK 994
>gi|215820652 StAR-related lipid transfer (START) domain containing 8
isoform b [Homo sapiens]
Length = 1023
Score = 653 bits (1684), Expect = 0.0
Identities = 335/577 (58%), Positives = 430/577 (74%), Gaps = 15/577 (2%)
Query: 525 SDLDSTGNSLNEPEEPSEIP--------ERRDSGVGASLTRSNRHRLRWHSFQSSHRPSL 576
S+LDS+GNS+NE E + ERRDSGVGASLTR R +LRWHSFQ+SHRPSL
Sbjct: 449 SELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCR-KLRWHSFQNSHRPSL 507
Query: 577 NSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDR 636
NS SL+IN Q Q+NLL K SLL+LTA +EKYT +K G+ W++PKFM+R K PDY+ +
Sbjct: 508 NSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQ 567
Query: 637 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 696
VFGVP ++VQRTGQPLPQSIQQAMRYLR+ CLDQVG+FRKSGVKSRIQ LRQMNE +
Sbjct: 568 HVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSP 627
Query: 697 DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLL 756
D V YEGQSAYDVAD+LKQYFRDLPEP+ T+KL+ TFLQIYQ +PKDQ L A +AA +LL
Sbjct: 628 DNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLL 687
Query: 757 PDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQ 816
PDENREVLQTLLYFLSD+ A+ +ENQMT NLAVCLAPS+FHLN K+++ SPR+ ++
Sbjct: 688 PDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRS 746
Query: 817 SLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGH 875
+G+P +DL++N+AATQGL+HMI++CKKLFQVP++M + +SY+ EL P AL
Sbjct: 747 LIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSP-PGPALAE 805
Query: 876 LGNDDSA--DYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRS 933
L +A ++++ + L ++ E+FKGW+S + EL+ +K +G PLRLW++
Sbjct: 806 LRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKA 865
Query: 934 VIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVL 993
EV A P +L R+L+E+ LWD DLL ++V+E L E+Y YV +SMAPHP RD+VVL
Sbjct: 866 STEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVL 925
Query: 994 RTWRTNLPKGACALLLTSVDHDR-APVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLR 1052
R WR++LP+G C L+ S+D ++ P GVR +L S+YL+EPCG G+S+LT++CR DLR
Sbjct: 926 RMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLR 985
Query: 1053 GHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTK 1089
G P+WY K FGHLCA EV KIRDSF +TK
Sbjct: 986 GRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETK 1022
Score = 69.7 bits (169), Expect = 1e-11
Identities = 60/187 (32%), Positives = 82/187 (43%), Gaps = 43/187 (22%)
Query: 68 TLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVP 127
TLN CA MKLE+ K+++DS+E+E C IS W FQ++SK WS + D+ +P
Sbjct: 2 TLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAP------ 55
Query: 128 GSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLP--SHAPPSEDAATPRTNSVI 185
PSPG L SV + S SLP + + P E A P
Sbjct: 56 -----------PSPG-----LPATSSCESVLTELSATSLPVITVSLPPEPADLP------ 93
Query: 186 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKS--KTRSLLKRMESLKLKSSH 243
L G S S + L S + +G + AK + RS LK +ESL+ K
Sbjct: 94 -------LPGRAPS----SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKS 142
Query: 244 HSKHKAP 250
S+ P
Sbjct: 143 GSQQAEP 149
Score = 65.9 bits (159), Expect = 2e-10
Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 45/217 (20%)
Query: 305 SSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESY 364
S S Q+E + +T V++ S +C G GF + R+++
Sbjct: 142 SGSQQAEPKHSPATSEKVSKASSFRSCR---GFLSAGFYRAKNWAATSAGGSGANTRKAW 198
Query: 365 PE---------------DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGP 409
D + ++P DHKPGTFP++L+ S P + +W+ G
Sbjct: 199 EAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPG----- 253
Query: 410 GHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENED----- 464
RR RR S S S S YDN+P LY + + E ED
Sbjct: 254 -----RRWGCEG------RRGSCGSTGSHASTYDNLPE--LYPAEPVMVGAEAEDEDDEE 300
Query: 465 ---IFPELDDILYHVKGMQRIVNQWSE-KFSDEGDSD 497
+ LDDIL HV G+Q+ V WS + D G D
Sbjct: 301 SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 337
>gi|215820650 StAR-related lipid transfer (START) domain containing 8
isoform a [Homo sapiens]
Length = 1103
Score = 653 bits (1684), Expect = 0.0
Identities = 335/577 (58%), Positives = 430/577 (74%), Gaps = 15/577 (2%)
Query: 525 SDLDSTGNSLNEPEEPSEIP--------ERRDSGVGASLTRSNRHRLRWHSFQSSHRPSL 576
S+LDS+GNS+NE E + ERRDSGVGASLTR R +LRWHSFQ+SHRPSL
Sbjct: 529 SELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCR-KLRWHSFQNSHRPSL 587
Query: 577 NSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDR 636
NS SL+IN Q Q+NLL K SLL+LTA +EKYT +K G+ W++PKFM+R K PDY+ +
Sbjct: 588 NSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQ 647
Query: 637 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 696
VFGVP ++VQRTGQPLPQSIQQAMRYLR+ CLDQVG+FRKSGVKSRIQ LRQMNE +
Sbjct: 648 HVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSP 707
Query: 697 DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLL 756
D V YEGQSAYDVAD+LKQYFRDLPEP+ T+KL+ TFLQIYQ +PKDQ L A +AA +LL
Sbjct: 708 DNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLL 767
Query: 757 PDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQ 816
PDENREVLQTLLYFLSD+ A+ +ENQMT NLAVCLAPS+FHLN K+++ SPR+ ++
Sbjct: 768 PDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRS 826
Query: 817 SLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGH 875
+G+P +DL++N+AATQGL+HMI++CKKLFQVP++M + +SY+ EL P AL
Sbjct: 827 LIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSP-PGPALAE 885
Query: 876 LGNDDSA--DYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRS 933
L +A ++++ + L ++ E+FKGW+S + EL+ +K +G PLRLW++
Sbjct: 886 LRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKA 945
Query: 934 VIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVL 993
EV A P +L R+L+E+ LWD DLL ++V+E L E+Y YV +SMAPHP RD+VVL
Sbjct: 946 STEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVL 1005
Query: 994 RTWRTNLPKGACALLLTSVDHDR-APVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLR 1052
R WR++LP+G C L+ S+D ++ P GVR +L S+YL+EPCG G+S+LT++CR DLR
Sbjct: 1006 RMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLR 1065
Query: 1053 GHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTK 1089
G P+WY K FGHLCA EV KIRDSF +TK
Sbjct: 1066 GRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETK 1102
Score = 144 bits (362), Expect = 6e-34
Identities = 94/242 (38%), Positives = 125/242 (51%), Gaps = 43/242 (17%)
Query: 13 QIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC 72
+ EAK AC+WL+ATGFPQY QL+E+ FP+DI VK+ H FLD D++ ALCRRL TLN C
Sbjct: 27 EAEAKRACEWLQATGFPQYVQLFEEGSFPLDIGSVKKNHGFLDEDSLGALCRRLMTLNNC 86
Query: 73 AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD 132
A MKLE+ K+++DS+E+E C IS W FQ++SK WS + D+ +P
Sbjct: 87 ASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAP----------- 135
Query: 133 SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLP--SHAPPSEDAATPRTNSVISVCSS 190
PSPG L SV + S SLP + + P E A P
Sbjct: 136 ------PSPG-----LPATSSCESVLTELSATSLPVITVSLPPEPADLP----------- 173
Query: 191 SNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKS--KTRSLLKRMESLKLKSSHHSKHK 248
L G S S + L S + +G + AK + RS LK +ESL+ K S+
Sbjct: 174 --LPGRAPS----SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKSGSQQA 227
Query: 249 AP 250
P
Sbjct: 228 EP 229
Score = 65.9 bits (159), Expect = 2e-10
Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 45/217 (20%)
Query: 305 SSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESY 364
S S Q+E + +T V++ S +C G GF + R+++
Sbjct: 222 SGSQQAEPKHSPATSEKVSKASSFRSCR---GFLSAGFYRAKNWAATSAGGSGANTRKAW 278
Query: 365 PE---------------DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGP 409
D + ++P DHKPGTFP++L+ S P + +W+ G
Sbjct: 279 EAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPG----- 333
Query: 410 GHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENED----- 464
RR RR S S S S YDN+P LY + + E ED
Sbjct: 334 -----RRWGCEG------RRGSCGSTGSHASTYDNLPE--LYPAEPVMVGAEAEDEDDEE 380
Query: 465 ---IFPELDDILYHVKGMQRIVNQWSE-KFSDEGDSD 497
+ LDDIL HV G+Q+ V WS + D G D
Sbjct: 381 SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 417
>gi|31543659 StAR-related lipid transfer (START) domain containing 8
isoform b [Homo sapiens]
Length = 1023
Score = 653 bits (1684), Expect = 0.0
Identities = 335/577 (58%), Positives = 430/577 (74%), Gaps = 15/577 (2%)
Query: 525 SDLDSTGNSLNEPEEPSEIP--------ERRDSGVGASLTRSNRHRLRWHSFQSSHRPSL 576
S+LDS+GNS+NE E + ERRDSGVGASLTR R +LRWHSFQ+SHRPSL
Sbjct: 449 SELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCR-KLRWHSFQNSHRPSL 507
Query: 577 NSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDR 636
NS SL+IN Q Q+NLL K SLL+LTA +EKYT +K G+ W++PKFM+R K PDY+ +
Sbjct: 508 NSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQ 567
Query: 637 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 696
VFGVP ++VQRTGQPLPQSIQQAMRYLR+ CLDQVG+FRKSGVKSRIQ LRQMNE +
Sbjct: 568 HVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSP 627
Query: 697 DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLL 756
D V YEGQSAYDVAD+LKQYFRDLPEP+ T+KL+ TFLQIYQ +PKDQ L A +AA +LL
Sbjct: 628 DNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLL 687
Query: 757 PDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQ 816
PDENREVLQTLLYFLSD+ A+ +ENQMT NLAVCLAPS+FHLN K+++ SPR+ ++
Sbjct: 688 PDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRS 746
Query: 817 SLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGH 875
+G+P +DL++N+AATQGL+HMI++CKKLFQVP++M + +SY+ EL P AL
Sbjct: 747 LIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSP-PGPALAE 805
Query: 876 LGNDDSA--DYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRS 933
L +A ++++ + L ++ E+FKGW+S + EL+ +K +G PLRLW++
Sbjct: 806 LRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKA 865
Query: 934 VIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVL 993
EV A P +L R+L+E+ LWD DLL ++V+E L E+Y YV +SMAPHP RD+VVL
Sbjct: 866 STEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVL 925
Query: 994 RTWRTNLPKGACALLLTSVDHDR-APVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLR 1052
R WR++LP+G C L+ S+D ++ P GVR +L S+YL+EPCG G+S+LT++CR DLR
Sbjct: 926 RMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLR 985
Query: 1053 GHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTK 1089
G P+WY K FGHLCA EV KIRDSF +TK
Sbjct: 986 GRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETK 1022
Score = 69.7 bits (169), Expect = 1e-11
Identities = 60/187 (32%), Positives = 82/187 (43%), Gaps = 43/187 (22%)
Query: 68 TLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVP 127
TLN CA MKLE+ K+++DS+E+E C IS W FQ++SK WS + D+ +P
Sbjct: 2 TLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAP------ 55
Query: 128 GSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLP--SHAPPSEDAATPRTNSVI 185
PSPG L SV + S SLP + + P E A P
Sbjct: 56 -----------PSPG-----LPATSSCESVLTELSATSLPVITVSLPPEPADLP------ 93
Query: 186 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKS--KTRSLLKRMESLKLKSSH 243
L G S S + L S + +G + AK + RS LK +ESL+ K
Sbjct: 94 -------LPGRAPS----SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKS 142
Query: 244 HSKHKAP 250
S+ P
Sbjct: 143 GSQQAEP 149
Score = 65.9 bits (159), Expect = 2e-10
Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 45/217 (20%)
Query: 305 SSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESY 364
S S Q+E + +T V++ S +C G GF + R+++
Sbjct: 142 SGSQQAEPKHSPATSEKVSKASSFRSCR---GFLSAGFYRAKNWAATSAGGSGANTRKAW 198
Query: 365 PE---------------DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGP 409
D + ++P DHKPGTFP++L+ S P + +W+ G
Sbjct: 199 EAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPG----- 253
Query: 410 GHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENED----- 464
RR RR S S S S YDN+P LY + + E ED
Sbjct: 254 -----RRWGCEG------RRGSCGSTGSHASTYDNLPE--LYPAEPVMVGAEAEDEDDEE 300
Query: 465 ---IFPELDDILYHVKGMQRIVNQWSE-KFSDEGDSD 497
+ LDDIL HV G+Q+ V WS + D G D
Sbjct: 301 SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 337
>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
Length = 663
Score = 99.4 bits (246), Expect = 2e-20
Identities = 64/195 (32%), Positives = 103/195 (52%), Gaps = 8/195 (4%)
Query: 623 KFMKRIKVPDYKDRSVFGVPLTVNVQRT-----GQPLPQSIQQAMRYLRNHCLDQVGLFR 677
K K +K+ KD +F VPLT +++ G +P Q+ + + L+ GL R
Sbjct: 307 KQQKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLR 365
Query: 678 KSGVKSRIQALRQMNEGAI--DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQ 735
G RI+ L Q E N+E +D A +LK + R+LP+PL++ + + F
Sbjct: 366 IPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQA 425
Query: 736 IYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPS 795
+ K Q+LQA+ ++LLPD NR+ L+ LL FL V ++N+MT N+A+ +AP+
Sbjct: 426 VQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPN 485
Query: 796 LFHLNTLKRENSSPR 810
LF + L ++S R
Sbjct: 486 LFMCHALGLKSSEQR 500
>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
Length = 771
Score = 91.7 bits (226), Expect = 3e-18
Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%)
Query: 654 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 713
+P+ + ++L H L VG+FR K R++ LR+ + ID E S +DVA +L
Sbjct: 207 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 266
Query: 714 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 773
K++ RD+P+PL+T +L F+ P++Q L ++ I LLP N + L LL FLS
Sbjct: 267 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 325
Query: 774 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 822
V V N+MT NLA P+L H ++ SS + + S
Sbjct: 326 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 375
Query: 823 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 853
E+ A + MI + LF VP ++
Sbjct: 376 -ARAEESTAIIAVVQKMIENYEALFMVPPDL 405
>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
sapiens]
Length = 765
Score = 91.7 bits (226), Expect = 3e-18
Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%)
Query: 654 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 713
+P+ + ++L H L VG+FR K R++ LR+ + ID E S +DVA +L
Sbjct: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
Query: 714 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 773
K++ RD+P+PL+T +L F+ P++Q L ++ I LLP N + L LL FLS
Sbjct: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
Query: 774 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 822
V V N+MT NLA P+L H ++ SS + + S
Sbjct: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 578
Query: 823 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 853
E+ A + MI + LF VP ++
Sbjct: 579 -ARAEESTAIIAVVQKMIENYEALFMVPPDL 608
>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
sapiens]
Length = 974
Score = 91.7 bits (226), Expect = 3e-18
Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%)
Query: 654 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 713
+P+ + ++L H L VG+FR K R++ LR+ + ID E S +DVA +L
Sbjct: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
Query: 714 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 773
K++ RD+P+PL+T +L F+ P++Q L ++ I LLP N + L LL FLS
Sbjct: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
Query: 774 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 822
V V N+MT NLA P+L H ++ SS + + S
Sbjct: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 578
Query: 823 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 853
E+ A + MI + LF VP ++
Sbjct: 579 -ARAEESTAIIAVVQKMIENYEALFMVPPDL 608
>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 88.2 bits (217), Expect = 4e-17
Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 21/220 (9%)
Query: 587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYK--DRSVFGVPLT 644
S+ M + +L++LTAL + + +KR K +K + +FGVPL
Sbjct: 226 SLQDMRKVPSLALIELTALCD------------ILGLDLKRSKAGKWKAAETRLFGVPLD 273
Query: 645 VNVQRTGQPLPQS-----IQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCV 699
++ + LP + +Q + L LD G+ R G ++R++ L Q E
Sbjct: 274 SLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAG 333
Query: 700 NYEGQSAY--DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 757
+ + D +D+LK++ R LP PL+T + F + QRLQ + I++LP
Sbjct: 334 LFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILP 393
Query: 758 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 797
+ NR L+ LL FL V A + N+MT N++ +AP+LF
Sbjct: 394 EPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLF 433
>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 88.2 bits (217), Expect = 4e-17
Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 21/220 (9%)
Query: 587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYK--DRSVFGVPLT 644
S+ M + +L++LTAL + + +KR K +K + +FGVPL
Sbjct: 226 SLQDMRKVPSLALIELTALCD------------ILGLDLKRSKAGKWKAAETRLFGVPLD 273
Query: 645 VNVQRTGQPLPQS-----IQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCV 699
++ + LP + +Q + L LD G+ R G ++R++ L Q E
Sbjct: 274 SLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAG 333
Query: 700 NYEGQSAY--DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 757
+ + D +D+LK++ R LP PL+T + F + QRLQ + I++LP
Sbjct: 334 LFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILP 393
Query: 758 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 797
+ NR L+ LL FL V A + N+MT N++ +AP+LF
Sbjct: 394 EPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLF 433
>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
sapiens]
Length = 622
Score = 88.2 bits (217), Expect = 4e-17
Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 21/220 (9%)
Query: 587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYK--DRSVFGVPLT 644
S+ M + +L++LTAL + + +KR K +K + +FGVPL
Sbjct: 226 SLQDMRKVPSLALIELTALCD------------ILGLDLKRSKAGKWKAAETRLFGVPLD 273
Query: 645 VNVQRTGQPLPQS-----IQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCV 699
++ + LP + +Q + L LD G+ R G ++R++ L Q E
Sbjct: 274 SLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAG 333
Query: 700 NYEGQSAY--DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 757
+ + D +D+LK++ R LP PL+T + F + QRLQ + I++LP
Sbjct: 334 LFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILP 393
Query: 758 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 797
+ NR L+ LL FL V A + N+MT N++ +AP+LF
Sbjct: 394 EPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLF 433
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 88.2 bits (217), Expect = 4e-17
Identities = 61/201 (30%), Positives = 97/201 (48%), Gaps = 23/201 (11%)
Query: 601 KLTALLEKYTPSNK-HGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQ 659
K A+LEK P + H WA ++ FG PL +++R+G+ + I+
Sbjct: 225 KALAVLEKTLPEMRAHQDKWA--------------EKPAFGTPLEEHLKRSGREIALPIE 270
Query: 660 QAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYD----VADMLKQ 715
+ L + + GLFR S+++ L+ A+DC Y VA LK
Sbjct: 271 ACVMLLLETGMKEEGLFRIGAGASKLKKLK----AALDCSTSHLDEFYSDPHAVAGALKS 326
Query: 716 YFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVT 775
Y R+LPEPLMT L E + Q+ +D++LQ + LP +N + L+ FL+ +
Sbjct: 327 YLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLA 386
Query: 776 AAVKENQMTPTNLAVCLAPSL 796
N+MTP+N+A+ L P+L
Sbjct: 387 QTSDVNKMTPSNIAIVLGPNL 407
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 88.2 bits (217), Expect = 4e-17
Identities = 61/201 (30%), Positives = 97/201 (48%), Gaps = 23/201 (11%)
Query: 601 KLTALLEKYTPSNK-HGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQ 659
K A+LEK P + H WA ++ FG PL +++R+G+ + I+
Sbjct: 225 KALAVLEKTLPEMRAHQDKWA--------------EKPAFGTPLEEHLKRSGREIALPIE 270
Query: 660 QAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYD----VADMLKQ 715
+ L + + GLFR S+++ L+ A+DC Y VA LK
Sbjct: 271 ACVMLLLETGMKEEGLFRIGAGASKLKKLK----AALDCSTSHLDEFYSDPHAVAGALKS 326
Query: 716 YFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVT 775
Y R+LPEPLMT L E + Q+ +D++LQ + LP +N + L+ FL+ +
Sbjct: 327 YLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLA 386
Query: 776 AAVKENQMTPTNLAVCLAPSL 796
N+MTP+N+A+ L P+L
Sbjct: 387 QTSDVNKMTPSNIAIVLGPNL 407
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 84.7 bits (208), Expect = 4e-16
Identities = 54/166 (32%), Positives = 94/166 (56%), Gaps = 8/166 (4%)
Query: 635 DRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEG 694
++ FG PL ++ +G+ + I+ + L + + GLFR + S+++ L+
Sbjct: 249 EKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLK----A 304
Query: 695 AIDC--VNYEGQSA--YDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIK 750
A+DC V+ + SA + +A LK Y R+LPEPLMT +L + ++Q +D++LQA+
Sbjct: 305 ALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALW 364
Query: 751 AAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 796
A LP N ++ L+ FLS ++ N+MTP+N+A+ L P+L
Sbjct: 365 NACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNL 410
>gi|59710113 Rho GTPase activating protein 28 isoform a [Homo
sapiens]
Length = 570
Score = 83.6 bits (205), Expect = 9e-16
Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%)
Query: 587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 646
S M ++ SL++LTA + + K K KV +D +FGVPLTV
Sbjct: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226
Query: 647 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 699
+ + G +P +Q+ + L+ G+FR SG ++++ R+ + D
Sbjct: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
Query: 700 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 758
++ + A MLK +FR+LP L + F+ + + P + + QA+ +M LPD
Sbjct: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
Query: 759 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 797
NR+ Q L+ F + V A +N+M+ N++ +AP+LF
Sbjct: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
Score = 41.2 bits (95), Expect = 0.005
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%)
Query: 133 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 185
S P D TL D S+ +E S SV L + LP H+ S + P N++
Sbjct: 52 SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110
Query: 186 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 245
+DD F P E SF + E ++ R+ LK+ E K
Sbjct: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160
Query: 246 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 281
+ ++ GL +G + E D +K++ L+ +E++A
Sbjct: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194
>gi|59710111 Rho GTPase activating protein 28 isoform b [Homo
sapiens]
Length = 563
Score = 83.6 bits (205), Expect = 9e-16
Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%)
Query: 587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 646
S M ++ SL++LTA + + K K KV +D +FGVPLTV
Sbjct: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226
Query: 647 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 699
+ + G +P +Q+ + L+ G+FR SG ++++ R+ + D
Sbjct: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
Query: 700 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 758
++ + A MLK +FR+LP L + F+ + + P + + QA+ +M LPD
Sbjct: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
Query: 759 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 797
NR+ Q L+ F + V A +N+M+ N++ +AP+LF
Sbjct: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
Score = 41.2 bits (95), Expect = 0.005
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%)
Query: 133 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 185
S P D TL D S+ +E S SV L + LP H+ S + P N++
Sbjct: 52 SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110
Query: 186 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 245
+DD F P E SF + E ++ R+ LK+ E K
Sbjct: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160
Query: 246 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 281
+ ++ GL +G + E D +K++ L+ +E++A
Sbjct: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194
>gi|40255080 hypothetical protein LOC158763 [Homo sapiens]
Length = 547
Score = 83.2 bits (204), Expect = 1e-15
Identities = 61/229 (26%), Positives = 108/229 (47%), Gaps = 24/229 (10%)
Query: 638 VFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAID 697
+ G +++ + +PQ ++ +++ H L VG+F R++ LR+ + +D
Sbjct: 219 LLGSKRKMSLNPIAKQIPQVVEACCQFIEKHGLSAVGIFTLEYSVQRVRQLREEFDQGLD 278
Query: 698 CVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 757
V + Q+ +DVA +LK++FRD+ + L+ + L +FL P+DQ L A++ + L+P
Sbjct: 279 VVLDDNQNVHDVAALLKEFFRDMKDSLLPDDLYMSFLLTATLKPQDQ-LSALQLLVYLMP 337
Query: 758 DENREVLQTLLYFLSDVT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKREN 806
+ + L+ LL L +T V N+MT TNLA+ +L +
Sbjct: 338 PCHSDTLERLLKALHKITENCEDSIGIDGQLVPGNRMTSTNLALVFGSALLKKGKFGKRE 397
Query: 807 SSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSR 855
S RK LG ++ +A+ + MI LFQVP + R
Sbjct: 398 S------RKTKLG------IDHYVASVNVVRAMIDNWDVLFQVPPHIQR 434
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 83.2 bits (204), Expect = 1e-15
Identities = 50/159 (31%), Positives = 83/159 (52%)
Query: 638 VFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAID 697
V+GV L ++Q G+ + I+ + L + + + GLFR + S ++ L+Q
Sbjct: 273 VYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH 332
Query: 698 CVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 757
+ + VA LK Y R+LPEPLMT L + +++ RLQA++ LP
Sbjct: 333 SLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLP 392
Query: 758 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 796
EN L+ L+ FL+ + + N+MTP+N+A+ L P+L
Sbjct: 393 PENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNL 431
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 82.8 bits (203), Expect = 2e-15
Identities = 52/164 (31%), Positives = 85/164 (51%), Gaps = 6/164 (3%)
Query: 637 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 696
S FG LT ++ +GQ +P ++ ++ H + G++R SGV S IQ LRQ G+
Sbjct: 17 SAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVD-GIYRLSGVTSNIQRLRQ-EFGSD 74
Query: 697 DCVNYEG----QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAA 752
C + Q + V + K YFR+LP PL+T +L E F + + P++ +L I+
Sbjct: 75 QCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNV 134
Query: 753 IMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 796
I LP + L+ L+ L+ + + + M NLA+ AP+L
Sbjct: 135 IQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNL 178
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 82.0 bits (201), Expect = 3e-15
Identities = 49/163 (30%), Positives = 90/163 (55%), Gaps = 2/163 (1%)
Query: 635 DRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQAL-RQMNE 693
+ + FGVPLT V +P+P I++ + Y+ L G++R SG KS +++L RQ ++
Sbjct: 1243 ESNYFGVPLTT-VVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQ 1301
Query: 694 GAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAI 753
+ + + VA +K +F +LP+PL+ + ++ ++ ++Q+L A+K +
Sbjct: 1302 DHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVL 1361
Query: 754 MLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 796
P EN EV + ++ L+ V+ K N MT NL++C P+L
Sbjct: 1362 KKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTL 1404
>gi|5803145 ralA binding protein 1 [Homo sapiens]
Length = 655
Score = 82.0 bits (201), Expect = 3e-15
Identities = 51/174 (29%), Positives = 92/174 (52%), Gaps = 7/174 (4%)
Query: 627 RIKVPDYKDRSVFGVPLTVNVQRT----GQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVK 682
+I VP+ K +FG+PL V+RT G LP ++ + Y+ + + G++R SG+K
Sbjct: 180 QIDVPNLKP--IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIK 237
Query: 683 SRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPK 742
S++ L+ + + N E VA +LKQY RDLPE L+T +L F + +
Sbjct: 238 SKVDELKAAYDRE-ESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTE 296
Query: 743 DQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 796
+++Q + + LP+ N ++ L+ + V A E +M N+++ L+P++
Sbjct: 297 TEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 82.0 bits (201), Expect = 3e-15
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 4/156 (2%)
Query: 654 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 713
+P +++ + ++ H L GL+RKSG +R + LRQ + V E + + +L
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 1771
Query: 714 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 773
KQ+ R+LPEPLMT FL+ + K ++L AI A + LP+ N L+ L++ L
Sbjct: 1772 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVK 1831
Query: 774 VTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSP 809
V N+M+P LA+ AP L +NS P
Sbjct: 1832 VALLEDVNRMSPGALAIIFAPCLLRC----PDNSDP 1863
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 82.0 bits (201), Expect = 3e-15
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 4/156 (2%)
Query: 654 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 713
+P +++ + ++ H L GL+RKSG +R + LRQ + V E + + +L
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 1771
Query: 714 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 773
KQ+ R+LPEPLMT FL+ + K ++L AI A + LP+ N L+ L++ L
Sbjct: 1772 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVK 1831
Query: 774 VTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSP 809
V N+M+P LA+ AP L +NS P
Sbjct: 1832 VALLEDVNRMSPGALAIIFAPCLLRC----PDNSDP 1863
>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
Length = 946
Score = 81.6 bits (200), Expect = 4e-15
Identities = 53/165 (32%), Positives = 84/165 (50%), Gaps = 4/165 (2%)
Query: 635 DRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEG 694
++ +FG + +Q +GQP+P ++ +R++ + L G+FR SG + R+ +R E
Sbjct: 501 NQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFER 560
Query: 695 AIDCVNYEGQSAYD---VADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKA 751
D + EG +A+D VA +LK YFR L PL L L + +R++ +
Sbjct: 561 GEDPL-VEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSR 619
Query: 752 AIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 796
+ LP VL+ L FL+ + EN M P NLAVC P+L
Sbjct: 620 LLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFGPTL 664
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 79.3 bits (194), Expect = 2e-14
Identities = 56/205 (27%), Positives = 101/205 (49%), Gaps = 4/205 (1%)
Query: 594 LQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQP 653
L+ + + + + +K T N F P ++ ++ Y VFG L QR
Sbjct: 610 LRSFKVSSIDSSEQKKTKKNLKKFLTRRPT-LQAVREKGYIKDQVFGSNLANLCQRENGT 668
Query: 654 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQM--NEGAIDCVNYEGQSAYDVAD 711
+P+ ++ + ++ H LD G++R SG + IQ LR ++ +D + + + + +
Sbjct: 669 VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITG 728
Query: 712 MLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFL 771
LK +FR+LPEPL T F+ + P+ QR+ A+K I LP N++ +Q L L
Sbjct: 729 ALKMFFRELPEPLFTFNHFNDFVNAIKQEPR-QRVAAVKDLIRQLPKPNQDTMQILFRHL 787
Query: 772 SDVTAAVKENQMTPTNLAVCLAPSL 796
V ++N+MT ++A+ P+L
Sbjct: 788 RRVIENGEKNRMTYQSIAIVFGPTL 812
>gi|89886350 Rho GTPase activating protein 11B [Homo sapiens]
Length = 267
Score = 79.0 bits (193), Expect = 2e-14
Identities = 57/175 (32%), Positives = 89/175 (50%), Gaps = 9/175 (5%)
Query: 638 VFGVPLTVNVQRTGQP----LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNE 693
+FGVP + + P +P + A L H + GLFRKSG R++AL+ +
Sbjct: 46 IFGVPFNA-LPHSAVPEYGHIPSFLVDACTSLEEH-IHTEGLFRKSGSVIRLKALKNKVD 103
Query: 694 GAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAI 753
C++ D+A +LKQ+FR+LPEP++ L E L+ Q + +++ +AI
Sbjct: 104 HGEGCLS--SAPPCDIAGLLKQFFRELPEPILPADLHEALLKA-QQLGTEEKNKAILLLS 160
Query: 754 MLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSS 808
LL D VL+ FL +V+ EN+M +NLAV AP+L + + SS
Sbjct: 161 CLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSS 215
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,632,805
Number of Sequences: 37866
Number of extensions: 2090854
Number of successful extensions: 7120
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 136
Number of HSP's that attempted gapping in prelim test: 6517
Number of HSP's gapped (non-prelim): 585
length of query: 1091
length of database: 18,247,518
effective HSP length: 113
effective length of query: 978
effective length of database: 13,968,660
effective search space: 13661349480
effective search space used: 13661349480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.