Search of human proteins with 123701922

Search of human proteins with 123701922

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|123701922 hypothetical protein LOC285596 [Homo sapiens]
         (310 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|123701922 hypothetical protein LOC285596 [Homo sapiens]            624   e-179
gi|118918431 hypothetical protein LOC202134 [Homo sapiens]            610   e-175
gi|118601002 hypothetical protein LOC653316 [Homo sapiens]            137   1e-32
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              45   1e-04
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po...    40   0.002
gi|124517695 ankyrin repeat domain 36B [Homo sapiens]                  40   0.002
gi|209862789 microtubule associated monoxygenase, calponin and L...    38   0.010
gi|56549111 optineurin [Homo sapiens]                                  37   0.017
gi|56549109 optineurin [Homo sapiens]                                  37   0.017
gi|20149572 optineurin [Homo sapiens]                                  37   0.017
gi|56549107 optineurin [Homo sapiens]                                  37   0.017
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po...    37   0.029
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa...    37   0.029
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa...    37   0.029
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    36   0.050
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]    35   0.065
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        35   0.085
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  35   0.085
gi|6005948 WW domain-containing binding protein 4 [Homo sapiens]       35   0.085
gi|58082089 hypothetical protein LOC161394 [Homo sapiens]              35   0.085
gi|63176611 modulator of estrogen induced transcription isoform ...    35   0.11 
gi|29171705 melanoma antigen family D, 2 [Homo sapiens]                35   0.11 
gi|19387846 melanoma antigen family D, 2 [Homo sapiens]                35   0.11 
gi|41350320 melanoma antigen family D, 2 [Homo sapiens]                35   0.11 
gi|4504487 histidine rich calcium binding protein precursor [Hom...    34   0.14 
gi|45359846 Ras-GTPase activating protein SH3 domain-binding pro...    34   0.14 
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               33   0.25 
gi|14249428 leucine-rich repeats and calponin homology (CH) doma...    33   0.25 
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]             33   0.32 
gi|189491776 nephrocystin 1 isoform 3 [Homo sapiens]                   33   0.32 

>gi|123701922 hypothetical protein LOC285596 [Homo sapiens]
          Length = 310

 Score =  624 bits (1610), Expect = e-179
 Identities = 310/310 (100%), Positives = 310/310 (100%)

Query: 1   MVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEI 60
           MVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEI
Sbjct: 1   MVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEI 60

Query: 61  LSETLPGSVKKRVCFPSEDHLEEFIAEHLPEASNQSLLTVAHADAGTQTNGDLEDLEEHG 120
           LSETLPGSVKKRVCFPSEDHLEEFIAEHLPEASNQSLLTVAHADAGTQTNGDLEDLEEHG
Sbjct: 61  LSETLPGSVKKRVCFPSEDHLEEFIAEHLPEASNQSLLTVAHADAGTQTNGDLEDLEEHG 120

Query: 121 PGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLE 180
           PGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLE
Sbjct: 121 PGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLE 180

Query: 181 DLEEHVPGQTVSEEATGVHMMQVDPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQVDPA 240
           DLEEHVPGQTVSEEATGVHMMQVDPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQVDPA
Sbjct: 181 DLEEHVPGQTVSEEATGVHMMQVDPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQVDPA 240

Query: 241 TLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRKPSKKSRWNV 300
           TLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRKPSKKSRWNV
Sbjct: 241 TLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRKPSKKSRWNV 300

Query: 301 LKCWDIFNIF 310
           LKCWDIFNIF
Sbjct: 301 LKCWDIFNIF 310


>gi|118918431 hypothetical protein LOC202134 [Homo sapiens]
          Length = 387

 Score =  610 bits (1574), Expect = e-175
 Identities = 304/310 (98%), Positives = 304/310 (98%)

Query: 1   MVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEI 60
           MVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEI
Sbjct: 78  MVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEI 137

Query: 61  LSETLPGSVKKRVCFPSEDHLEEFIAEHLPEASNQSLLTVAHADAGTQTNGDLEDLEEHG 120
           LSETLPGSVKKRVCFPSEDHLEEFIAEHLPEASNQSLLTVAHAD G QTNGDLEDLEEHG
Sbjct: 138 LSETLPGSVKKRVCFPSEDHLEEFIAEHLPEASNQSLLTVAHADTGIQTNGDLEDLEEHG 197

Query: 121 PGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLE 180
           PGQTVSEEATEVH MEGDPDTLAE LIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLE
Sbjct: 198 PGQTVSEEATEVHMMEGDPDTLAELLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLE 257

Query: 181 DLEEHVPGQTVSEEATGVHMMQVDPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQVDPA 240
           DLEEHVPGQTVSEEATGVHMMQVDPAT AKSDLEDLEEHVP QTVSEEATGVHMMQVDPA
Sbjct: 258 DLEEHVPGQTVSEEATGVHMMQVDPATPAKSDLEDLEEHVPGQTVSEEATGVHMMQVDPA 317

Query: 241 TLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRKPSKKSRWNV 300
           TLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRKPSKKSRWNV
Sbjct: 318 TLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRKPSKKSRWNV 377

Query: 301 LKCWDIFNIF 310
           LKCWDIFNIF
Sbjct: 378 LKCWDIFNIF 387



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 13/109 (11%)

Query: 174 PQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPA--TLAKSDLEDLEE-HV-----PEQTV 225
           P+   +ED +E +  +  SE+  GVHM+  D       K  L  L E H+       Q  
Sbjct: 52  PRVASMEDYDEDLVQEASSEDVLGVHMVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEA 111

Query: 226 SEEATGVHMMQVDPATLAK-----QLEDSTITGSHQQMSASPSSAPAEE 269
            + + GV   + D  +L K     ++   T+ GS ++    PS    EE
Sbjct: 112 MKTSLGVPQCERDEGSLGKPLCPPEILSETLPGSVKKRVCFPSEDHLEE 160


>gi|118601002 hypothetical protein LOC653316 [Homo sapiens]
          Length = 114

 Score =  137 bits (345), Expect = 1e-32
 Identities = 80/130 (61%), Positives = 87/130 (66%), Gaps = 34/130 (26%)

Query: 151 LQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAK 210
           L+EL  Y+  ++  E +KTSLGVPQRGDLE                              
Sbjct: 19  LRELHLYSTWKKYQEAMKTSLGVPQRGDLE------------------------------ 48

Query: 211 SDLEDLEEHVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPSSAPAEEA 270
               DLEEH+P QTVSEEATGVHMMQVDPAT AK+LEDSTITGSHQQMSASPSSAPAEEA
Sbjct: 49  ----DLEEHLPGQTVSEEATGVHMMQVDPATPAKKLEDSTITGSHQQMSASPSSAPAEEA 104

Query: 271 TEKTKVEEEV 280
           TEKTKVEEEV
Sbjct: 105 TEKTKVEEEV 114



 Score = 91.7 bits (226), Expect = 8e-19
 Identities = 51/67 (76%), Positives = 51/67 (76%), Gaps = 11/67 (16%)

Query: 1  MVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEI 60
          MVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQ     G L       E 
Sbjct: 1  MVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQ----RGDL-------ED 49

Query: 61 LSETLPG 67
          L E LPG
Sbjct: 50 LEEHLPG 56



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 35/81 (43%), Positives = 43/81 (53%), Gaps = 6/81 (7%)

Query: 106 GTQTNGDLEDLEEHGPGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGEEEDPE 165
           G    GDLEDLEEH PGQTVSEEAT VH M+ DP T A+ L      E S+  G  +   
Sbjct: 40  GVPQRGDLEDLEEHLPGQTVSEEATGVHMMQVDPATPAKKL------EDSTITGSHQQMS 93

Query: 166 EVKTSLGVPQRGDLEDLEEHV 186
              +S    +  +   +EE V
Sbjct: 94  ASPSSAPAEEATEKTKVEEEV 114


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 54/222 (24%), Positives = 89/222 (40%), Gaps = 26/222 (11%)

Query: 74   CFPSEDHLEEFIAEHLPEASNQSLLTVAHADAGTQTNGDLEDLEEHGPGQTVSEEATEVH 133
            C  +ED  E    E    ++ + L     A+   Q    LE+ +E   G+ + EEA ++ 
Sbjct: 1269 CATNEDEAERDSEEQRASSNLEQL-----AENTVQEEVQLEETKEGTEGEGLQEEAVQLE 1323

Query: 134  TMEGDPDTLAEFLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSE 193
              + +     E +    L+E     GE +  EE +          LE++EE   G+ + E
Sbjct: 1324 ETKTEEGLQEEGV---QLEETKETEGEGQQEEEAQ----------LEEIEE-TGGEGLQE 1369

Query: 194  EATGVHMMQVDPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQVDPAT----LAKQLEDS 249
            E  GV + +V          E LEE + E+ + EE + VH  ++  A+       Q +D 
Sbjct: 1370 E--GVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGS-VHGQELSEASSPDGKGSQEDDP 1426

Query: 250  TITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRK 291
                   + SAS    PAE   E T+    +    P    R+
Sbjct: 1427 VQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQ 1468


>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
           polyclonal antibodies [Homo sapiens]
          Length = 868

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 16/136 (11%)

Query: 181 DLEEHVPG---QTVSEEATGVHMMQVDPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQV 237
           D E  VP    +T  E+ +G    Q  PA  A SD +D   ++P +    + +G    Q 
Sbjct: 55  DKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQK 114

Query: 238 DPA------------TLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKP 285
            PA             +A +++D  I G+          A  +E    + +  E+K  + 
Sbjct: 115 QPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGE- 173

Query: 286 KKKTRKPSKKSRWNVL 301
           K  T  P K+S   V+
Sbjct: 174 KSGTVSPQKQSAQKVI 189


>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
          Length = 1121

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 31/136 (22%), Positives = 54/136 (39%), Gaps = 13/136 (9%)

Query: 178 DLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQV 237
           D ED   ++  +T  E+ +G    Q  PA  A SD +D   ++P +    + +G    Q 
Sbjct: 308 DKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQK 367

Query: 238 DPA------------TLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKP 285
            PA             +A +++D  I G+             +E    + +  E+K  + 
Sbjct: 368 QPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGE- 426

Query: 286 KKKTRKPSKKSRWNVL 301
           K  T  P K+S   V+
Sbjct: 427 KSGTVSPQKQSAQKVI 442


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 55/212 (25%), Positives = 76/212 (35%), Gaps = 47/212 (22%)

Query: 102  HADAGTQTNGDLEDLEEHGPGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGEE 161
            HA    ++  +LE  +  GPG    EE  E +  E + D        D  +E SS  G +
Sbjct: 970  HALLKGKSEEELEASKSFGPGNEEEEEEEEEYEEEEEED-------YDEEEEESSEAGNQ 1022

Query: 162  E--------DPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDL 213
                     DP E++  +      + E+ E   P    S             A+ A  D 
Sbjct: 1023 RLQQVMHAADPLEIQADVHWTHIREREEEERMAPASESS-------------ASGAPLDE 1069

Query: 214  EDLEEHVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPSSA-------- 265
             DLEE V  +    E  G      DP     +L+D       Q  S SPS A        
Sbjct: 1070 NDLEEDVDSEPA--EIEGEAAEDGDPGDTGAELDDD------QHWSDSPSDADRELRLPC 1121

Query: 266  PAEEATE---KTKVEEEVKTRKPKKKTRKPSK 294
            PAE   E   +   +EE     PK + R PS+
Sbjct: 1122 PAEGEAELELRVSEDEEKLPASPKHQERGPSQ 1153


>gi|56549111 optineurin [Homo sapiens]
          Length = 577

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 12/129 (9%)

Query: 154 LSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDL 213
           LS    E+   E+ K+ L V Q    + L+EH       EE T     +VD A L K   
Sbjct: 369 LSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVL-KELS 427

Query: 214 EDLEEHVPEQTVSEEATGVHMMQVD--PATLAKQLED-STITGSHQQMSASPSSAPAEEA 270
           E LE       ++E+A     +Q+D    T+AKQ ED  T+T    QM    S   AE A
Sbjct: 428 EKLE-------LAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA 480

Query: 271 TEKTKVEEE 279
             + K+ EE
Sbjct: 481 A-REKIHEE 488


>gi|56549109 optineurin [Homo sapiens]
          Length = 577

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 12/129 (9%)

Query: 154 LSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDL 213
           LS    E+   E+ K+ L V Q    + L+EH       EE T     +VD A L K   
Sbjct: 369 LSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVL-KELS 427

Query: 214 EDLEEHVPEQTVSEEATGVHMMQVD--PATLAKQLED-STITGSHQQMSASPSSAPAEEA 270
           E LE       ++E+A     +Q+D    T+AKQ ED  T+T    QM    S   AE A
Sbjct: 428 EKLE-------LAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA 480

Query: 271 TEKTKVEEE 279
             + K+ EE
Sbjct: 481 A-REKIHEE 488


>gi|20149572 optineurin [Homo sapiens]
          Length = 577

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 12/129 (9%)

Query: 154 LSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDL 213
           LS    E+   E+ K+ L V Q    + L+EH       EE T     +VD A L K   
Sbjct: 369 LSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVL-KELS 427

Query: 214 EDLEEHVPEQTVSEEATGVHMMQVD--PATLAKQLED-STITGSHQQMSASPSSAPAEEA 270
           E LE       ++E+A     +Q+D    T+AKQ ED  T+T    QM    S   AE A
Sbjct: 428 EKLE-------LAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA 480

Query: 271 TEKTKVEEE 279
             + K+ EE
Sbjct: 481 A-REKIHEE 488


>gi|56549107 optineurin [Homo sapiens]
          Length = 577

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 12/129 (9%)

Query: 154 LSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDL 213
           LS    E+   E+ K+ L V Q    + L+EH       EE T     +VD A L K   
Sbjct: 369 LSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVL-KELS 427

Query: 214 EDLEEHVPEQTVSEEATGVHMMQVD--PATLAKQLED-STITGSHQQMSASPSSAPAEEA 270
           E LE       ++E+A     +Q+D    T+AKQ ED  T+T    QM    S   AE A
Sbjct: 428 EKLE-------LAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA 480

Query: 271 TEKTKVEEE 279
             + K+ EE
Sbjct: 481 A-REKIHEE 488


>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
           polyclonal antibodies [Homo sapiens]
          Length = 1430

 Score = 36.6 bits (83), Expect = 0.029
 Identities = 36/138 (26%), Positives = 57/138 (41%), Gaps = 20/138 (14%)

Query: 181 DLEEHVPG---QTVSEEATGVHMMQVDPATLAKSDLEDLEEHVPEQ--------TVSEE- 228
           D E  VP    +T  E+ +G    Q  PA  A SD +D   ++P +        TVS + 
Sbjct: 617 DKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQK 676

Query: 229 -----ATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTR 283
                AT V    V  + +A +++D  I G+          A  +E    + +  E+K  
Sbjct: 677 QLAWKATSVKKDSV--SNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDG 734

Query: 284 KPKKKTRKPSKKSRWNVL 301
           + K  T  P K+S   V+
Sbjct: 735 E-KSGTVSPQKQSAQKVI 751


>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
           sapiens]
          Length = 1782

 Score = 36.6 bits (83), Expect = 0.029
 Identities = 66/281 (23%), Positives = 102/281 (36%), Gaps = 50/281 (17%)

Query: 26  STWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEILSETLPGSVKKRVCFPSEDHLEEFI 85
           ST  + QE MK S+  P+ E  +  +   +    ++     GS KKR    S        
Sbjct: 648 STASEMQEEMKGSVEEPKPEEPKRKVDTSVSWEALICV---GSSKKRARRGSSSD----- 699

Query: 86  AEHLPEA--SNQSLLTVAHADAGTQTNGDLEDLEEHGPGQTVSEEATEVHTMEGDPDTLA 143
            E  P+A   +      A  D  T T+G L   +EH PGQ  S         EG+  +  
Sbjct: 700 EEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTW 759

Query: 144 EFLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQV 203
           E   R V     S +  EE  E+     GV         E   P     +E + V + + 
Sbjct: 760 ESFKRLVTPRKKSKSKLEEKSEDSIAGSGV---------EHSTPDTEPGKEESWVSIKKF 810

Query: 204 DPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPS 263
            P    K   +  +E  P                        +ED+  TG+++  S  P+
Sbjct: 811 IPGRRKKRP-DGKQEQAP------------------------VEDAGPTGANEDDSDVPA 845

Query: 264 SAPAEE--ATEKTKVEEEVKTRKPKKKTRKPSKKSRWNVLK 302
             P  E  A E+ K+E     ++ +K   +P +K+   V K
Sbjct: 846 VVPLSEYDAVEREKME----AQQAQKSAEQPEQKAATEVSK 882



 Score = 33.1 bits (74), Expect = 0.32
 Identities = 33/128 (25%), Positives = 50/128 (39%), Gaps = 11/128 (8%)

Query: 45   ERDEGSLGKPLCPPEILSETLPGSVKKRVCFPSEDHLEEFIAEHLPEASNQSLLTVAHAD 104
            E + G  G    P +     L   ++K +  P ED   + + +  PE  N +L       
Sbjct: 1664 EEEGGGAGTKSVPEDDGHALLAERIEKSLVEPKEDEKGDDVDD--PENQNSAL------- 1714

Query: 105  AGTQTNGDL--EDLEEHGPGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGEEE 162
            A T  +G L  E  + +GP Q   E+A EV   EG   + ++  I    QE       E 
Sbjct: 1715 ADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQERES 1774

Query: 163  DPEEVKTS 170
               E+  S
Sbjct: 1775 AKSELTES 1782



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 26/132 (19%)

Query: 165  EEVKTSLGV----PQRGDLE----------DLEEHVPGQTVSEEATGVHMMQVDPATLA- 209
            +EVK S+ +    P+ G LE          ++ +    Q V  E T   M+  +  T A 
Sbjct: 1522 QEVKVSVAIEDLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAH 1581

Query: 210  --KSDLEDLEEHVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITG-SHQQMSASPSSAP 266
              K+D +D  +   ++    +A+        P T AK+  +ST  G +H  +S   S   
Sbjct: 1582 VIKADSQDAGQETEKEGEEPQASA---QDETPITSAKEESESTAVGQAHSDISKDMS--- 1635

Query: 267  AEEATEKTKVEE 278
              EA+EKT   E
Sbjct: 1636 --EASEKTMTVE 1645



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 55/252 (21%), Positives = 88/252 (34%), Gaps = 31/252 (12%)

Query: 53   KPLCPPEILSETLPGSVKKRVCFPSEDHLEEFI----AEHLPEASNQSLLTV-------A 101
            +P    +++ +T P S +K           E +    AE L    +Q ++          
Sbjct: 1104 EPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPDSV 1163

Query: 102  HADAGTQTNGDLEDLEEHGPGQTVSEEATEVH--------TMEGDPDTLAEFLIRDVLQE 153
                 ++T+G     +   PG T  +E  E+H        T  G  +  A    ++    
Sbjct: 1164 ETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQKERPPA 1223

Query: 154  LSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVS----EEATGVHMMQVDPATLA 209
             SS+  +EE  E+ K          LE  ++ V  +TVS     E T       D  T  
Sbjct: 1224 PSSFVFQEETKEQSK------MEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKD 1277

Query: 210  KSDLEDLEEHVPEQ-TVS-EEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPSSAPA 267
                E LE  +    TVS E+ T V +          + +D+    SH +   SP     
Sbjct: 1278 VPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVEREM 1337

Query: 268  EEATEKTKVEEE 279
                E+ K E E
Sbjct: 1338 VVQVEREKTEAE 1349


>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
           sapiens]
          Length = 1684

 Score = 36.6 bits (83), Expect = 0.029
 Identities = 66/281 (23%), Positives = 102/281 (36%), Gaps = 50/281 (17%)

Query: 26  STWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEILSETLPGSVKKRVCFPSEDHLEEFI 85
           ST  + QE MK S+  P+ E  +  +   +    ++     GS KKR    S        
Sbjct: 550 STASEMQEEMKGSVEEPKPEEPKRKVDTSVSWEALICV---GSSKKRARRGSSSD----- 601

Query: 86  AEHLPEA--SNQSLLTVAHADAGTQTNGDLEDLEEHGPGQTVSEEATEVHTMEGDPDTLA 143
            E  P+A   +      A  D  T T+G L   +EH PGQ  S         EG+  +  
Sbjct: 602 EEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTW 661

Query: 144 EFLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQV 203
           E   R V     S +  EE  E+     GV         E   P     +E + V + + 
Sbjct: 662 ESFKRLVTPRKKSKSKLEEKSEDSIAGSGV---------EHSTPDTEPGKEESWVSIKKF 712

Query: 204 DPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPS 263
            P    K   +  +E  P                        +ED+  TG+++  S  P+
Sbjct: 713 IPGRRKKRP-DGKQEQAP------------------------VEDAGPTGANEDDSDVPA 747

Query: 264 SAPAEE--ATEKTKVEEEVKTRKPKKKTRKPSKKSRWNVLK 302
             P  E  A E+ K+E     ++ +K   +P +K+   V K
Sbjct: 748 VVPLSEYDAVEREKME----AQQAQKSAEQPEQKAATEVSK 784



 Score = 33.1 bits (74), Expect = 0.32
 Identities = 33/128 (25%), Positives = 50/128 (39%), Gaps = 11/128 (8%)

Query: 45   ERDEGSLGKPLCPPEILSETLPGSVKKRVCFPSEDHLEEFIAEHLPEASNQSLLTVAHAD 104
            E + G  G    P +     L   ++K +  P ED   + + +  PE  N +L       
Sbjct: 1566 EEEGGGAGTKSVPEDDGHALLAERIEKSLVEPKEDEKGDDVDD--PENQNSAL------- 1616

Query: 105  AGTQTNGDL--EDLEEHGPGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGEEE 162
            A T  +G L  E  + +GP Q   E+A EV   EG   + ++  I    QE       E 
Sbjct: 1617 ADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQERES 1676

Query: 163  DPEEVKTS 170
               E+  S
Sbjct: 1677 AKSELTES 1684



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 26/132 (19%)

Query: 165  EEVKTSLGV----PQRGDLE----------DLEEHVPGQTVSEEATGVHMMQVDPATLA- 209
            +EVK S+ +    P+ G LE          ++ +    Q V  E T   M+  +  T A 
Sbjct: 1424 QEVKVSVAIEDLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAH 1483

Query: 210  --KSDLEDLEEHVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITG-SHQQMSASPSSAP 266
              K+D +D  +   ++    +A+        P T AK+  +ST  G +H  +S   S   
Sbjct: 1484 VIKADSQDAGQETEKEGEEPQASA---QDETPITSAKEESESTAVGQAHSDISKDMS--- 1537

Query: 267  AEEATEKTKVEE 278
              EA+EKT   E
Sbjct: 1538 --EASEKTMTVE 1547



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 55/252 (21%), Positives = 88/252 (34%), Gaps = 31/252 (12%)

Query: 53   KPLCPPEILSETLPGSVKKRVCFPSEDHLEEFI----AEHLPEASNQSLLTV-------A 101
            +P    +++ +T P S +K           E +    AE L    +Q ++          
Sbjct: 1006 EPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPDSV 1065

Query: 102  HADAGTQTNGDLEDLEEHGPGQTVSEEATEVH--------TMEGDPDTLAEFLIRDVLQE 153
                 ++T+G     +   PG T  +E  E+H        T  G  +  A    ++    
Sbjct: 1066 ETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQKERPPA 1125

Query: 154  LSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVS----EEATGVHMMQVDPATLA 209
             SS+  +EE  E+ K          LE  ++ V  +TVS     E T       D  T  
Sbjct: 1126 PSSFVFQEETKEQSK------MEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKD 1179

Query: 210  KSDLEDLEEHVPEQ-TVS-EEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPSSAPA 267
                E LE  +    TVS E+ T V +          + +D+    SH +   SP     
Sbjct: 1180 VPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVEREM 1239

Query: 268  EEATEKTKVEEE 279
                E+ K E E
Sbjct: 1240 VVQVEREKTEAE 1251


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 35.8 bits (81), Expect = 0.050
 Identities = 44/215 (20%), Positives = 91/215 (42%), Gaps = 25/215 (11%)

Query: 91   EASNQSLLTVAHADAGTQTNGDLEDLEEHGPGQTVSEEATEVHTMEGDPDTLAEFL---- 146
            +A ++ LL V      T+  G+LE++E     Q + E+      ++ + +  AE      
Sbjct: 855  QAKDEELLKVKEKQ--TKVEGELEEMERKHQ-QLLEEKNILAEQLQAETELFAEAEEMRA 911

Query: 147  --------IRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGV 198
                    + ++L +L S   EEE+  ++  +     +  ++DLEE      + EE    
Sbjct: 912  RLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQ-----LDEEEGAR 966

Query: 199  HMMQVDPATLAKSDLEDLEEHV--PEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQ 256
              +Q++  T A++ ++ +EE +   E   S+      +M+   A  + QL +      + 
Sbjct: 967  QKLQLEKVT-AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025

Query: 257  QMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRK 291
                +       +  E+ K EE  KTR+  +K ++
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEE--KTRQELEKAKR 1058



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 34/158 (21%), Positives = 65/158 (41%), Gaps = 29/158 (18%)

Query: 147  IRDVLQELSSYNGEEEDPEEVKTSLG---VPQRGDLEDLEEHVPGQTVSEEATGVHMMQV 203
            IR + +E +S   ++E+ EE + +L    +  +  L D ++ V      ++   +  ++ 
Sbjct: 1338 IRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV-----DDDLGTIESLEE 1392

Query: 204  DPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQ------- 256
                L K D E L      Q + E+A     ++     L ++L+D T+   HQ       
Sbjct: 1393 AKKKLLK-DAEALS-----QRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNL 1446

Query: 257  --------QMSASPSSAPAEEATEKTKVEEEVKTRKPK 286
                    Q+ A   S  A  A E+ + E E + ++ K
Sbjct: 1447 EKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETK 1484


>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
          Length = 710

 Score = 35.4 bits (80), Expect = 0.065
 Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 22/134 (16%)

Query: 160 EEEDPEEVKT--SLGVPQRGDLEDLEEHVPGQTVS---EEATGVHMMQVDPATLAKSDLE 214
           E++D E+ +T  S   P    + D E+ VP        E+ +G    Q  PA  A SD +
Sbjct: 558 EKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKK 617

Query: 215 DLEEHVPEQTVSEEATGVHMMQVDPA------------TLAKQLEDSTITGSHQQMSASP 262
           D   ++P +    + +G    Q  PA             +A +++D  I G     + SP
Sbjct: 618 DSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRG-----TVSP 672

Query: 263 SSAPAEEATEKTKV 276
               A++   K KV
Sbjct: 673 QKQSAQKVIFKKKV 686


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 35.0 bits (79), Expect = 0.085
 Identities = 35/123 (28%), Positives = 47/123 (38%), Gaps = 16/123 (13%)

Query: 114 EDLEEHGPGQTVSEEATEVHTMEGDPDTLAE--------------FLIRDVLQELSSYNG 159
           E  E  GP +   E  TE    E   D   E               L RD  ++ S  NG
Sbjct: 819 ETAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNG 878

Query: 160 EEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDLEDLEEH 219
           E   PE  + SL V      E  E+ V  QT+  +A    + +  P    + D  +LEE 
Sbjct: 879 ESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVER--PVANRECDPAELEEK 936

Query: 220 VPE 222
           VP+
Sbjct: 937 VPK 939


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 35.0 bits (79), Expect = 0.085
 Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 188 GQTVS--EEATGVHMMQVDPATLAKSDLEDLE--EHVPEQTVSEEATGVHMMQVDPATLA 243
           GQ +S  E    +   + D A+   +++  L   E +P+  V +E    H      ++ +
Sbjct: 142 GQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSS 201

Query: 244 KQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRKPSKKS 296
              + S+ + S    S S S+   +    K K  +  +  K +KK RK SKKS
Sbjct: 202 SDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKS 254


>gi|6005948 WW domain-containing binding protein 4 [Homo sapiens]
          Length = 376

 Score = 35.0 bits (79), Expect = 0.085
 Identities = 20/86 (23%), Positives = 34/86 (39%), Gaps = 1/86 (1%)

Query: 213 LEDLEEHVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPSSAPAEEATE 272
           + ++++   ++   EE        ++ A L    ED    G   ++   PS  P      
Sbjct: 44  ISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESEI-LEPSITPVTSTIP 102

Query: 273 KTKVEEEVKTRKPKKKTRKPSKKSRW 298
            T    + K +K KKK +K   K RW
Sbjct: 103 PTSTSNQQKEKKEKKKRKKDPSKGRW 128


>gi|58082089 hypothetical protein LOC161394 [Homo sapiens]
          Length = 674

 Score = 35.0 bits (79), Expect = 0.085
 Identities = 46/214 (21%), Positives = 82/214 (38%), Gaps = 24/214 (11%)

Query: 104 DAGTQTNGDLEDLEEHGPGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGEEED 163
           D+G   +G+LE      PG     E  E  TM      L   + ++   E    + +E +
Sbjct: 9   DSGPDEDGELEPERPELPGLHKLYENAEPDTMAKADSKLPAEIYQEPQPETEEEDFKEGE 68

Query: 164 PEEVKTSL----GVPQRGDLEDLEEHVPGQT---VSEEATGVHMMQVD----------PA 206
           P+  K       G  Q G  ++ +  VP +T   + +E       ++             
Sbjct: 69  PDSAKNVQLKPGGTSQEGIAKESKRDVPSETEPGIHQEVKSETSREMGEFFKDLEAPMDE 128

Query: 207 TLAKSDLEDLEE---HVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPS 263
           T  +SDLE  EE   +V E    E A       V P     ++  +T+   + ++    +
Sbjct: 129 THKESDLEPPEEAKPNVTEDVFLESAMETDPDPVPPTETMSEVSGATVRERNLELLEEET 188

Query: 264 SAPAEEATEKTKVEEEVKTRKPKKKTRK--PSKK 295
                E  E  +V+ E    +P ++T++  PS+K
Sbjct: 189 EPGVPE--ESLRVQHEETGLEPPEQTKQDFPSEK 220


>gi|63176611 modulator of estrogen induced transcription isoform a
           [Homo sapiens]
          Length = 1034

 Score = 34.7 bits (78), Expect = 0.11
 Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 37/224 (16%)

Query: 101 AHADAGTQTNGDLEDLEEHGPGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGE 160
           AH   G   N +L+D EE G  +  +  + E+  +  + +  A  LI    + +     E
Sbjct: 114 AHEQDG---NDELKDSEEFGENEEENVHSKEL--LSAEENKRAHELIE--AEGIEDIEKE 166

Query: 161 EEDPEEVKTSLG------VPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDL- 213
           + + +E++   G        Q G+ E+ E+ + G    +    V        +LA++D  
Sbjct: 167 DIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGS--GDGTQEVSKPLPSEGSLAEADHT 224

Query: 214 --EDLEEHVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPSSAPAE--- 268
             E++E H   +   ++   V +   D  TL    +D   TG + +++ S +S P +   
Sbjct: 225 AHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQD 284

Query: 269 ---EATEKT-------------KVEEEVKTRKPKKKTRKPSKKS 296
              ++ EK              K E+ VK    +K+ R+ SKK+
Sbjct: 285 AIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKA 328


>gi|29171705 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score = 34.7 bits (78), Expect = 0.11
 Identities = 37/156 (23%), Positives = 62/156 (39%), Gaps = 13/156 (8%)

Query: 150 VLQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLA 209
           ++Q L +     E PE  K S  +    D++       G + + E +     +  PAT A
Sbjct: 26  MMQTLLTVTQNVEVPETPKASKALEVSEDVK--VSKASGVSKATEVSKTPEAREAPATQA 83

Query: 210 KSDLEDLEEHVPEQTVSEEATGVHMMQVDP------ATLAKQLE---DSTITGSHQQMSA 260
            S  +  +  V        A        DP      AT  K++    D+ +    Q+  A
Sbjct: 84  SSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEA 143

Query: 261 SPSSAPAEEATEKTKV--EEEVKTRKPKKKTRKPSK 294
           +PS APA+E   ++     +E +  +PK K +K  K
Sbjct: 144 APSQAPADEPEPESAAAQSQENQDTRPKVKAKKARK 179


>gi|19387846 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score = 34.7 bits (78), Expect = 0.11
 Identities = 37/156 (23%), Positives = 62/156 (39%), Gaps = 13/156 (8%)

Query: 150 VLQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLA 209
           ++Q L +     E PE  K S  +    D++       G + + E +     +  PAT A
Sbjct: 26  MMQTLLTVTQNVEVPETPKASKALEVSEDVK--VSKASGVSKATEVSKTPEAREAPATQA 83

Query: 210 KSDLEDLEEHVPEQTVSEEATGVHMMQVDP------ATLAKQLE---DSTITGSHQQMSA 260
            S  +  +  V        A        DP      AT  K++    D+ +    Q+  A
Sbjct: 84  SSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEA 143

Query: 261 SPSSAPAEEATEKTKV--EEEVKTRKPKKKTRKPSK 294
           +PS APA+E   ++     +E +  +PK K +K  K
Sbjct: 144 APSQAPADEPEPESAAAQSQENQDTRPKVKAKKARK 179


>gi|41350320 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score = 34.7 bits (78), Expect = 0.11
 Identities = 37/156 (23%), Positives = 62/156 (39%), Gaps = 13/156 (8%)

Query: 150 VLQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLA 209
           ++Q L +     E PE  K S  +    D++       G + + E +     +  PAT A
Sbjct: 26  MMQTLLTVTQNVEVPETPKASKALEVSEDVK--VSKASGVSKATEVSKTPEAREAPATQA 83

Query: 210 KSDLEDLEEHVPEQTVSEEATGVHMMQVDP------ATLAKQLE---DSTITGSHQQMSA 260
            S  +  +  V        A        DP      AT  K++    D+ +    Q+  A
Sbjct: 84  SSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEA 143

Query: 261 SPSSAPAEEATEKTKV--EEEVKTRKPKKKTRKPSK 294
           +PS APA+E   ++     +E +  +PK K +K  K
Sbjct: 144 APSQAPADEPEPESAAAQSQENQDTRPKVKAKKARK 179


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 51/208 (24%), Positives = 77/208 (37%), Gaps = 38/208 (18%)

Query: 91  EASNQSLLTVAHADAGTQTNGDLEDLEEHGPGQTVSEEATEV--HTMEGDPDTLAEFLIR 148
           E   +  +   H  A  Q  G   D E+        E  TEV  H     P    E +  
Sbjct: 378 EEEEEITVQFGHYVASHQPRGHKSDEEDFQ-----DEYKTEVPHHHHHRVPREEDEEVSA 432

Query: 149 DVLQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATL 208
           ++  +  S+    +D E      G  QRG ++++  H PG TV +          D + L
Sbjct: 433 ELGHQAPSHRQSHQDEET-----GHGQRGSIKEMSHHPPGHTVVK----------DRSHL 477

Query: 209 AKSDLEDLEEHVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPS----- 263
            K D E+ +E        EE  G H    +    ++Q E  T  GS  Q           
Sbjct: 478 RKDDSEEEKE-------KEEDPGSH---EEDDESSEQGEKGTHHGSRDQEDEEDEEEGHG 527

Query: 264 -SAPAEEATEKTKVEEEVKTRKPKKKTR 290
            S   EE  E+ K EEE +  + +++ R
Sbjct: 528 LSLNQEEEEEEDKEEEEEEEDEERREER 555


>gi|45359846 Ras-GTPase activating protein SH3 domain-binding
           protein 2 isoform b [Homo sapiens]
          Length = 449

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 32/137 (23%), Positives = 58/137 (42%), Gaps = 17/137 (12%)

Query: 160 EEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDLEDLEEH 219
           +EE  +EV+           E+ EE  P     +E       +  P T    +  +   H
Sbjct: 146 DEESEDEVE-----------EEQEERQPSPEPVQENANSGYYEAHPVTNGIEEPLEESSH 194

Query: 220 VPE-QTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEE 278
            PE +  SE  T     QV+   L ++LE+ + T       A P S P E    + + + 
Sbjct: 195 EPEPEPESETKTEELKPQVEEKNL-EELEEKSTTPP----PAEPVSLPQEPPKPRVEAKP 249

Query: 279 EVKTRKPKKKTRKPSKK 295
           EV+++ P+ + ++P ++
Sbjct: 250 EVQSQPPRVREQRPRER 266


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 33.5 bits (75), Expect = 0.25
 Identities = 37/150 (24%), Positives = 59/150 (39%), Gaps = 20/150 (13%)

Query: 164 PEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDLEDLE---EHV 220
           P+   + +  PQR   + L  +   Q VS+      M Q+ P     S+L +L     HV
Sbjct: 666 PQASSSRMQCPQR---QGLRHNTTSQNVSKRP----MQQMQPTAPRNSNLRELPIAPSHV 718

Query: 221 PEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMS--------ASPSSAPAEEATE 272
            E + S   +     QV P   A       + GS             ASP + P EEA  
Sbjct: 719 IEMS-SSRCSATPSAQVKPIVSASP-PSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKT 776

Query: 273 KTKVEEEVKTRKPKKKTRKPSKKSRWNVLK 302
           +T+  +E +  +  +   +  K+ R  +LK
Sbjct: 777 ETEFPDEDEETRLYRLKIEEQKRLREEILK 806


>gi|14249428 leucine-rich repeats and calponin homology (CH) domain
           containing 3 [Homo sapiens]
          Length = 712

 Score = 33.5 bits (75), Expect = 0.25
 Identities = 36/160 (22%), Positives = 64/160 (40%), Gaps = 12/160 (7%)

Query: 109 TNGDLE---DLEEHGPGQTVSEEATEVHTMEG-DPDTLAEFLIRDVLQELSSYNGEEEDP 164
           TNG +E   D  ++    T  EE  EV   +G DPD+L+   +  + Q   S+ G    P
Sbjct: 364 TNGGVEHDLDQIDYIDSCTAEEEEAEVRQPKGPDPDSLSSQFMAYIEQRRISHEGSPVKP 423

Query: 165 EEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDLE--DLEEHVPE 222
                 + + +    ED+  ++    V  E + +  +      L+ +DLE     E + E
Sbjct: 424 ------VAIREFQKTEDMRRYLHQNRVPAEPSSLLSLSASHNQLSHTDLELHQRREQLVE 477

Query: 223 QTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASP 262
           +T  E        + +     +   D+ +    Q+ S SP
Sbjct: 478 RTRREAQLAALQYEEEKIRTKQIQRDAVLDFVKQKASQSP 517


>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
          Length = 2440

 Score = 33.1 bits (74), Expect = 0.32
 Identities = 42/216 (19%), Positives = 77/216 (35%), Gaps = 15/216 (6%)

Query: 80  HLEEFIAEHLPEASNQSL--LTVAHADAGTQTNGDLEDLEEHGPGQTVSEEATEVHTMEG 137
           +L+  + +H  + S +      V+  ++   T    ED +     +  + E +EV  ++ 
Sbjct: 674 NLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKP 733

Query: 138 DPDTLAEFLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLED--LEEHVPGQTVSEEA 195
             D+      R   +         E       SL VP     ED  +E  V     +E A
Sbjct: 734 SEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETA 793

Query: 196 TGVHMMQ----------VDPATLAKSDLEDLEEHVPEQTVSE-EATGVHMMQVDPATLAK 244
             + + Q           DP    K+D  D+E  VPE   S+ E        +D A+   
Sbjct: 794 EQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKV 853

Query: 245 QLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEV 280
           +  D  +  + Q  +  P      +++     +E+V
Sbjct: 854 EPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDV 889


>gi|189491776 nephrocystin 1 isoform 3 [Homo sapiens]
          Length = 677

 Score = 33.1 bits (74), Expect = 0.32
 Identities = 44/216 (20%), Positives = 87/216 (40%), Gaps = 18/216 (8%)

Query: 77  SEDHLEEFIAEHLPEASNQSLLTVAHA-DAGTQTNGDLEDLEEHGPGQTVSEEATEVHTM 135
           SE  L+E +  +  +   Q  + +  A D        L   +E  P    ++   E HT+
Sbjct: 29  SESQLKEALEPNKRQHIYQRCIQLKQAIDENKNALQKLSKADESAPVANYNQRKEEEHTL 88

Query: 136 ----EGDPDTLAEFLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTV 191
                     LA  + R+ + E+ +   EEE+ E   +     +  D E+ EE       
Sbjct: 89  LDKLTQQLQGLAVTISRENITEVGAPTEEEEESESEDSEDSGGEEEDAEEEEEEKEENES 148

Query: 192 SEEATGVHMM--------QVDPATLAKSDLEDLEEHVPE-QTVSEEATG----VHMMQVD 238
            + +TG   +        QV   T  K ++  + E  P+   ++++A G    V    ++
Sbjct: 149 HKWSTGEEYIAVGDFTAQQVGDLTFKKGEILLVIEKKPDGWWIAKDAKGNEGLVPRTYLE 208

Query: 239 PATLAKQLEDSTITGSHQQMSASPSSAPAEEATEKT 274
           P +  ++ ++S+  GS + + A   +A   E  ++T
Sbjct: 209 PYSEEEEGQESSEEGSEEDVEAVDETADGAEVKQRT 244


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.126    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,482,472
Number of Sequences: 37866
Number of extensions: 684913
Number of successful extensions: 3177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 162
Number of HSP's that attempted gapping in prelim test: 2950
Number of HSP's gapped (non-prelim): 385
length of query: 310
length of database: 18,247,518
effective HSP length: 102
effective length of query: 208
effective length of database: 14,385,186
effective search space: 2992118688
effective search space used: 2992118688
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.