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Search of human proteins with 32967262
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens]
(549 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens] 1080 0.0
gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens] 1060 0.0
gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens] 1060 0.0
gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens] 1060 0.0
gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens] 1037 0.0
gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens] 973 0.0
gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens] 969 0.0
gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens] 969 0.0
gi|4506467 radixin [Homo sapiens] 429 e-120
gi|4505257 moesin [Homo sapiens] 424 e-119
gi|161702986 ezrin [Homo sapiens] 421 e-117
gi|21614499 ezrin [Homo sapiens] 421 e-117
gi|32967268 neurofibromin 2 isoform 8 [Homo sapiens] 201 2e-51
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 115 1e-25
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i... 115 1e-25
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is... 115 1e-25
gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo s... 115 1e-25
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i... 113 4e-25
gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform... 113 4e-25
gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform... 113 4e-25
gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis... 108 1e-23
gi|150010540 FERM domain containing 4B [Homo sapiens] 108 2e-23
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho... 107 2e-23
gi|42716291 erythrocyte membrane protein band 4.1 (elliptocytosi... 103 5e-22
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i... 102 7e-22
gi|223941876 protein tyrosine phosphatase, non-receptor type 3 i... 102 7e-22
gi|207113199 erythrocyte membrane protein band 4.1-like 2 isofor... 102 7e-22
gi|207113195 erythrocyte membrane protein band 4.1-like 2 isofor... 102 7e-22
gi|4503579 erythrocyte membrane protein band 4.1-like 2 isoform ... 102 7e-22
gi|116063562 FERM domain containing 4A [Homo sapiens] 100 3e-21
>gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens]
Length = 549
Score = 1080 bits (2793), Expect = 0.0
Identities = 549/549 (100%), Positives = 549/549 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG 120
FFGLQYTIKDTVAWLKMDKKVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG 120
Query: 121 FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY 180
FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY
Sbjct: 121 FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY 180
Query: 181 FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID 240
FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID
Sbjct: 181 FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID 240
Query: 241 VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR 300
VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR
Sbjct: 241 VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR 300
Query: 301 EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK 360
EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK
Sbjct: 301 EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK 360
Query: 361 AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA 420
AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA
Sbjct: 361 AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA 420
Query: 421 REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI 480
REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI
Sbjct: 421 REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI 480
Query: 481 EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ 540
EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ
Sbjct: 481 EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ 540
Query: 541 AQGRRPICI 549
AQGRRPICI
Sbjct: 541 AQGRRPICI 549
>gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 1060 bits (2741), Expect = 0.0
Identities = 549/590 (93%), Positives = 549/590 (93%), Gaps = 41/590 (6%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKV--------------------------------------- 81
FFGLQYTIKDTVAWLKMDKKV
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 82 --KKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 139
KKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
Query: 140 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 199
PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG
Sbjct: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
Query: 200 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 259
LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC
Sbjct: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
Query: 260 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 319
IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL
Sbjct: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
Query: 320 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 379
LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE
Sbjct: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
Query: 380 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 439
EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT
Sbjct: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
Query: 440 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 499
YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN
Sbjct: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
Query: 500 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 549
ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI
Sbjct: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 590
>gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 1060 bits (2741), Expect = 0.0
Identities = 549/590 (93%), Positives = 549/590 (93%), Gaps = 41/590 (6%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKV--------------------------------------- 81
FFGLQYTIKDTVAWLKMDKKV
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 82 --KKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 139
KKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
Query: 140 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 199
PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG
Sbjct: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
Query: 200 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 259
LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC
Sbjct: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
Query: 260 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 319
IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL
Sbjct: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
Query: 320 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 379
LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE
Sbjct: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
Query: 380 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 439
EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT
Sbjct: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
Query: 440 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 499
YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN
Sbjct: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
Query: 500 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 549
ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI
Sbjct: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 590
>gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 1060 bits (2741), Expect = 0.0
Identities = 549/590 (93%), Positives = 549/590 (93%), Gaps = 41/590 (6%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKV--------------------------------------- 81
FFGLQYTIKDTVAWLKMDKKV
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 82 --KKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 139
KKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
Query: 140 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 199
PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG
Sbjct: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
Query: 200 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 259
LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC
Sbjct: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
Query: 260 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 319
IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL
Sbjct: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
Query: 320 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 379
LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE
Sbjct: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
Query: 380 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 439
EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT
Sbjct: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
Query: 440 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 499
YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN
Sbjct: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
Query: 500 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 549
ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI
Sbjct: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 590
>gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens]
Length = 595
Score = 1037 bits (2681), Expect = 0.0
Identities = 539/586 (91%), Positives = 540/586 (92%), Gaps = 41/586 (6%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKV--------------------------------------- 81
FFGLQYTIKDTVAWLKMDKKV
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 82 --KKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 139
KKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
Query: 140 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 199
PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG
Sbjct: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
Query: 200 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 259
LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC
Sbjct: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
Query: 260 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 319
IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL
Sbjct: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
Query: 320 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 379
LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE
Sbjct: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
Query: 380 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 439
EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT
Sbjct: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
Query: 440 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 499
YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN
Sbjct: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
Query: 500 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRR 545
ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKK Q +
Sbjct: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKLTLQSAK 586
>gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens]
Length = 548
Score = 973 bits (2516), Expect = 0.0
Identities = 509/549 (92%), Positives = 517/549 (94%), Gaps = 1/549 (0%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCE+ + V L + +
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEVLDHDVSKEEPVTFHF-LAKFY 59
Query: 61 FFGLQYTIKDTVAWLKMDKKVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG 120
+ + + +VKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG
Sbjct: 60 PENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG 119
Query: 121 FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY 180
FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY
Sbjct: 120 FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY 179
Query: 181 FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID 240
FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID
Sbjct: 180 FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID 239
Query: 241 VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR 300
VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR
Sbjct: 240 VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR 299
Query: 301 EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK 360
EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK
Sbjct: 300 EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK 359
Query: 361 AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA 420
AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA
Sbjct: 360 AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA 419
Query: 421 REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI 480
REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI
Sbjct: 420 REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI 479
Query: 481 EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ 540
EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ
Sbjct: 480 EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ 539
Query: 541 AQGRRPICI 549
AQGRRPICI
Sbjct: 540 AQGRRPICI 548
>gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 969 bits (2506), Expect = 0.0
Identities = 507/549 (92%), Positives = 507/549 (92%), Gaps = 42/549 (7%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCE
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCE---------------------- 38
Query: 61 FFGLQYTIKDTVAWLKMDKKVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG 120
VKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG
Sbjct: 39 --------------------VKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG 78
Query: 121 FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY 180
FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY
Sbjct: 79 FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY 138
Query: 181 FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID 240
FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID
Sbjct: 139 FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID 198
Query: 241 VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR 300
VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR
Sbjct: 199 VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR 258
Query: 301 EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK 360
EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK
Sbjct: 259 EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK 318
Query: 361 AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA 420
AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA
Sbjct: 319 AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA 378
Query: 421 REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI 480
REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI
Sbjct: 379 REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI 438
Query: 481 EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ 540
EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ
Sbjct: 439 EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ 498
Query: 541 AQGRRPICI 549
AQGRRPICI
Sbjct: 499 AQGRRPICI 507
>gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 969 bits (2506), Expect = 0.0
Identities = 507/549 (92%), Positives = 507/549 (92%), Gaps = 42/549 (7%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCE
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCE---------------------- 38
Query: 61 FFGLQYTIKDTVAWLKMDKKVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG 120
VKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG
Sbjct: 39 --------------------VKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRG 78
Query: 121 FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY 180
FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY
Sbjct: 79 FLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNY 138
Query: 181 FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID 240
FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID
Sbjct: 139 FAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKID 198
Query: 241 VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR 300
VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR
Sbjct: 199 VFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAR 258
Query: 301 EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK 360
EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK
Sbjct: 259 EKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQK 318
Query: 361 AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA 420
AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA
Sbjct: 319 AAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEA 378
Query: 421 REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI 480
REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI
Sbjct: 379 REAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEI 438
Query: 481 EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ 540
EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ
Sbjct: 439 EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQ 498
Query: 541 AQGRRPICI 549
AQGRRPICI
Sbjct: 499 AQGRRPICI 507
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 429 bits (1102), Expect = e-120
Identities = 234/569 (41%), Positives = 346/569 (60%), Gaps = 52/569 (9%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-IKDTVAWLKM 77
PK VR+ TMDAE+EF + GK LFD V +T+GLRE WFFGLQY K WLK+
Sbjct: 2 PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKL 61
Query: 78 DKKVKKQ-----------------------------------------ILDEKIYCPPEA 96
+KKV +Q IL+++IYCPPE
Sbjct: 62 NKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPET 121
Query: 97 SVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRG 156
+VLLASYAVQAKYGDY+ +HK G+LA + LLP+RV+ +++T E WEERI W+ EHRG
Sbjct: 122 AVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRG 181
Query: 157 RARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFP 216
R+++ MEYLKIAQDLEMYGVNYF I+NKKGTEL LGVDALGL+IY+ +++LTPKI FP
Sbjct: 182 MLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFP 241
Query: 217 WNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLE 276
W+EIRNIS++DK+F IKP+DKK F F + +LR+NK IL LC+GNH+L+MRRRK D++E
Sbjct: 242 WSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIE 301
Query: 277 VQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRS 336
VQQMKAQAREEK +KQ+ER +L EK+ RE AE+ ++ +ER ++ E E +++
Sbjct: 302 VQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKA 361
Query: 337 EETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIK----ATAIRTEEEKRLMEQKVLEA 392
++ + KA ++E K ++A E+E + + A A + ++ + EQ E
Sbjct: 362 QKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAEL 421
Query: 393 EVLALKMA---EESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAP 449
K+A E +++ +EA + + A+E + K++L + + P PP P+ P
Sbjct: 422 AEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPP 481
Query: 450 LPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALK 509
+ + S + + + ++ E+E+V +K++ +++QL L +E+ +
Sbjct: 482 TENEHDEHDENNAEASAELSNEGV--MNHRSEEERVTETQKNERVKKQLQALSSELAQAR 539
Query: 510 LKERETALDILHNENSDRGGSSKHNTIKK 538
+ ++T D+LH EN + G K+ T+++
Sbjct: 540 DETKKTQNDVLHAENV-KAGRDKYKTLRQ 567
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 424 bits (1091), Expect = e-119
Identities = 242/569 (42%), Positives = 348/569 (61%), Gaps = 58/569 (10%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-IKDTVAWLKM 77
PKT +VR+ TMDAE+EF + GK LFD V +T+GLRE WFFGLQY K WLK+
Sbjct: 2 PKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKL 61
Query: 78 DKKV-----------------------------------------KKQILDEKIYCPPEA 96
+KKV K+ IL++ IYCPPE
Sbjct: 62 NKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPET 121
Query: 97 SVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRG 156
+VLLASYAVQ+KYGD++ VHK G+LA ++LLP+RV+ +++ + WEERI W+ EHRG
Sbjct: 122 AVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRG 181
Query: 157 RARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFP 216
R++A +EYLKIAQDLEMYGVNYF+I+NKKG+EL LGVDALGL+IY+ +RLTPKI FP
Sbjct: 182 MLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFP 241
Query: 217 WNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLE 276
W+EIRNIS++DK+F IKP+DKK F F + +LR+NK IL LC+GNH+L+MRRRK D++E
Sbjct: 242 WSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIE 301
Query: 277 VQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELER-------RLLQMKEEATMA 329
VQQMKAQAREEK +KQMER L EK+ RE AE+ ++++ER RL Q++E+ A
Sbjct: 302 VQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKA 361
Query: 330 NEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKV 389
+ L A L ++ + + EA+ LA++ EAE+ + A + ++K+ EQ
Sbjct: 362 QQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKE---ALLQASRDQKKTQEQLA 418
Query: 390 LEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAP 449
LE L ++++ R K+ + + Q+A+ + ++ E+ T + P + PA
Sbjct: 419 LEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAE-PAE 477
Query: 450 LPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALK 509
D N G S D + M + E+E+ EK++ +Q+ L L +E+ +
Sbjct: 478 NEQDEQDEN--GAEASADLRADAMAK--DRSEEERTTEAEKNERVQKHLKALTSELANAR 533
Query: 510 LKERETALDILHNENSDRGGSSKHNTIKK 538
+ ++TA D++H EN R G K+ T+++
Sbjct: 534 DESKKTANDMIHAENM-RLGRDKYKTLRQ 561
Score = 33.5 bits (75), Expect = 0.52
Identities = 35/158 (22%), Positives = 70/158 (44%), Gaps = 14/158 (8%)
Query: 274 SLEVQQMKAQ------AREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEAT 327
+LE+ ++ A+ AR++K + +E Q+ A+ ++E+ E+TR EL+ +
Sbjct: 418 ALEMAELTARISQLEMARQKKESEAVEWQQKAQ--MVQEDLEKTRAELKTAMSTPHVAEP 475
Query: 328 MANEALMRSEE----TADLLAEKA--QITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEE 381
NE + E +ADL A+ +EEE A+K ++ ++ + + +E
Sbjct: 476 AENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDE 535
Query: 382 KRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQE 419
+ ++ AE + L + R KQ + E
Sbjct: 536 SKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDE 573
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 421 bits (1081), Expect = e-117
Identities = 243/576 (42%), Positives = 348/576 (60%), Gaps = 63/576 (10%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTI-KDTVAWLKM 77
PK VR+ TMDAE+EF + GK LFD V +T+GLRE W+FGL Y K WLK+
Sbjct: 2 PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61
Query: 78 DKKVKKQ-----------------------------------------ILDEKIYCPPEA 96
DKKV Q IL ++IYCPPE
Sbjct: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121
Query: 97 SVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRG 156
+VLL SYAVQAK+GDY+ VHK G+L+ E L+P+RV++ +++T + WE+RI W+AEHRG
Sbjct: 122 AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRG 181
Query: 157 RARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFP 216
+D A +EYLKIAQDLEMYG+NYF I+NKKGT+L LGVDALGL+IY+ +++LTPKI FP
Sbjct: 182 MLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP 241
Query: 217 WNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLE 276
W+EIRNIS++DK+F IKP+DKK F F + +LR+NK ILQLC+GNH+L+MRRRK D++E
Sbjct: 242 WSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIE 301
Query: 277 VQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRS 336
VQQMKAQAREEK +KQ+ERQ+L EK+ RE ER ++++ R ++ E ++
Sbjct: 302 VQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKA 361
Query: 337 EETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEE-KRLMEQKVLEAEVL 395
E ++A EEE K +A E + ++ + A+R +EE +R ++ E L
Sbjct: 362 ERELSEQIQRALQLEEERK----RAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQL 417
Query: 396 ALKMAEESERRA--KEADQLKQDLQEAREAERRAKQKLLE-IATKPTYPPMNPIPAPLPP 452
A ++AE + + A +EA + K+D E E + RAK+ + + TK + P P PP
Sbjct: 418 AAELAEYTAKIALLEEARRRKED--EVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPP 475
Query: 453 DI--PSFNLIGDSLSFDFKDTD--MKRLSME------IEKEKVEYMEKSKHLQEQLNELK 502
+ P + +SL + + LS E E++++ EK++ +Q QL L
Sbjct: 476 PVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLS 535
Query: 503 TEIEALKLKERETALDILHNENSDRGGSSKHNTIKK 538
+E+ + + + T DI+HNEN R G K+ T+++
Sbjct: 536 SELSQARDENKRTHNDIIHNENM-RQGRDKYKTLRQ 570
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 421 bits (1081), Expect = e-117
Identities = 243/576 (42%), Positives = 348/576 (60%), Gaps = 63/576 (10%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTI-KDTVAWLKM 77
PK VR+ TMDAE+EF + GK LFD V +T+GLRE W+FGL Y K WLK+
Sbjct: 2 PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61
Query: 78 DKKVKKQ-----------------------------------------ILDEKIYCPPEA 96
DKKV Q IL ++IYCPPE
Sbjct: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121
Query: 97 SVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRG 156
+VLL SYAVQAK+GDY+ VHK G+L+ E L+P+RV++ +++T + WE+RI W+AEHRG
Sbjct: 122 AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRG 181
Query: 157 RARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFP 216
+D A +EYLKIAQDLEMYG+NYF I+NKKGT+L LGVDALGL+IY+ +++LTPKI FP
Sbjct: 182 MLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP 241
Query: 217 WNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLE 276
W+EIRNIS++DK+F IKP+DKK F F + +LR+NK ILQLC+GNH+L+MRRRK D++E
Sbjct: 242 WSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIE 301
Query: 277 VQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRS 336
VQQMKAQAREEK +KQ+ERQ+L EK+ RE ER ++++ R ++ E ++
Sbjct: 302 VQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKA 361
Query: 337 EETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEE-KRLMEQKVLEAEVL 395
E ++A EEE K +A E + ++ + A+R +EE +R ++ E L
Sbjct: 362 ERELSEQIQRALQLEEERK----RAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQL 417
Query: 396 ALKMAEESERRA--KEADQLKQDLQEAREAERRAKQKLLE-IATKPTYPPMNPIPAPLPP 452
A ++AE + + A +EA + K+D E E + RAK+ + + TK + P P PP
Sbjct: 418 AAELAEYTAKIALLEEARRRKED--EVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPP 475
Query: 453 DI--PSFNLIGDSLSFDFKDTD--MKRLSME------IEKEKVEYMEKSKHLQEQLNELK 502
+ P + +SL + + LS E E++++ EK++ +Q QL L
Sbjct: 476 PVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLS 535
Query: 503 TEIEALKLKERETALDILHNENSDRGGSSKHNTIKK 538
+E+ + + + T DI+HNEN R G K+ T+++
Sbjct: 536 SELSQARDENKRTHNDIIHNENM-RQGRDKYKTLRQ 570
>gi|32967268 neurofibromin 2 isoform 8 [Homo sapiens]
Length = 165
Score = 201 bits (510), Expect = 2e-51
Identities = 108/149 (72%), Positives = 108/149 (72%), Gaps = 41/149 (27%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKK---------------------------------------- 80
FFGLQYTIKDTVAWLKMDKK
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 81 -VKKQILDEKIYCPPEASVLLASYAVQAK 108
VKKQILDEKIYCPPEASVLLASYAVQAK
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 115 bits (288), Expect = 1e-25
Identities = 97/361 (26%), Positives = 159/361 (44%), Gaps = 63/361 (17%)
Query: 24 VRIVTMDAE-MEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTV---------- 72
V I+ ++ + +E C+ K KD+FD+V +GL E F L T+KD
Sbjct: 574 VNIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALA-TLKDNEYFFVDPDLKL 632
Query: 73 ------AWLKMDKK------------------------------------VKKQILDEKI 90
W + KK ++K IL+E++
Sbjct: 633 TKVAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERM 692
Query: 91 YCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAW 150
+C E S+LLAS A+QA+YGDY P VH + E LP RV+ ++ +E +
Sbjct: 693 HCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLS--YIKEELPKL 750
Query: 151 YAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAI--RNKKGTELLLGVDALGLHIYDPENR 208
+ + G + E E+E+LK+ Q L YGV++ + K T +LLGV + G+ +++ N
Sbjct: 751 HNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNG 810
Query: 209 L-TPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFM 267
+ T + FPW E + IS+S K+ T++ I F + ++ + +L LC H +
Sbjct: 811 VRTLVLRFPWRETKKISFSKKKITLQNTSDGIK-HGFQTDNSKICQYLLHLCSYQHKFQL 869
Query: 268 RRRKADSLEVQQMKAQAREEKARKQMERQR---LAREKQMREEAERTRDELERRLLQMKE 324
+ R S + Q +A Q E R + R A T ++L R L ++
Sbjct: 870 QMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQA 929
Query: 325 E 325
E
Sbjct: 930 E 930
>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
Length = 2485
Score = 115 bits (288), Expect = 1e-25
Identities = 97/361 (26%), Positives = 159/361 (44%), Gaps = 63/361 (17%)
Query: 24 VRIVTMDAE-MEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTV---------- 72
V I+ ++ + +E C+ K KD+FD+V +GL E F L T+KD
Sbjct: 574 VNIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALA-TLKDNEYFFVDPDLKL 632
Query: 73 ------AWLKMDKK------------------------------------VKKQILDEKI 90
W + KK ++K IL+E++
Sbjct: 633 TKVAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERM 692
Query: 91 YCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAW 150
+C E S+LLAS A+QA+YGDY P VH + E LP RV+ ++ +E +
Sbjct: 693 HCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLS--YIKEELPKL 750
Query: 151 YAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAI--RNKKGTELLLGVDALGLHIYDPENR 208
+ + G + E E+E+LK+ Q L YGV++ + K T +LLGV + G+ +++ N
Sbjct: 751 HNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNG 810
Query: 209 L-TPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFM 267
+ T + FPW E + IS+S K+ T++ I F + ++ + +L LC H +
Sbjct: 811 VRTLVLRFPWRETKKISFSKKKITLQNTSDGIK-HGFQTDNSKICQYLLHLCSYQHKFQL 869
Query: 268 RRRKADSLEVQQMKAQAREEKARKQMERQR---LAREKQMREEAERTRDELERRLLQMKE 324
+ R S + Q +A Q E R + R A T ++L R L ++
Sbjct: 870 QMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQA 929
Query: 325 E 325
E
Sbjct: 930 E 930
>gi|5453992 protein tyrosine phosphatase, non-receptor type 13
isoform 2 [Homo sapiens]
Length = 2466
Score = 115 bits (288), Expect = 1e-25
Identities = 97/361 (26%), Positives = 159/361 (44%), Gaps = 63/361 (17%)
Query: 24 VRIVTMDAE-MEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTV---------- 72
V I+ ++ + +E C+ K KD+FD+V +GL E F L T+KD
Sbjct: 574 VNIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALA-TLKDNEYFFVDPDLKL 632
Query: 73 ------AWLKMDKK------------------------------------VKKQILDEKI 90
W + KK ++K IL+E++
Sbjct: 633 TKVAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERM 692
Query: 91 YCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAW 150
+C E S+LLAS A+QA+YGDY P VH + E LP RV+ ++ +E +
Sbjct: 693 HCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLS--YIKEELPKL 750
Query: 151 YAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAI--RNKKGTELLLGVDALGLHIYDPENR 208
+ + G + E E+E+LK+ Q L YGV++ + K T +LLGV + G+ +++ N
Sbjct: 751 HNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNG 810
Query: 209 L-TPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFM 267
+ T + FPW E + IS+S K+ T++ I F + ++ + +L LC H +
Sbjct: 811 VRTLVLRFPWRETKKISFSKKKITLQNTSDGIK-HGFQTDNSKICQYLLHLCSYQHKFQL 869
Query: 268 RRRKADSLEVQQMKAQAREEKARKQMERQR---LAREKQMREEAERTRDELERRLLQMKE 324
+ R S + Q +A Q E R + R A T ++L R L ++
Sbjct: 870 QMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQA 929
Query: 325 E 325
E
Sbjct: 930 E 930
>gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo
sapiens]
Length = 1087
Score = 115 bits (287), Expect = 1e-25
Identities = 89/307 (28%), Positives = 140/307 (45%), Gaps = 58/307 (18%)
Query: 6 ASRMSFSSLKR-KQPKTFTVRIVTMDAEMEFNC--EMKWKGKDLFDLVCRTLGLRETWFF 62
+S++S S LK K+PK+ +++ +D E+ C E + +G+ LFD VC L L E +F
Sbjct: 93 SSKLSRSPLKIVKKPKSMQCKVILLDGS-EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYF 151
Query: 63 GLQY-TIKDTVAWLKMDKKVKKQI--------LDEKIYCPPEASV--------------- 98
GL Y ++ WL K++KKQ+ + K Y P A +
Sbjct: 152 GLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRD 211
Query: 99 ---------------LLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMW 143
LL SY VQ++ GDYDP ++++ P L
Sbjct: 212 DIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHTKEL-------- 263
Query: 144 EERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIY 203
E+++ + HRG EAEM +L+ A+ L MYGV+ ++ +G E++LGV A GL IY
Sbjct: 264 EDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIY 323
Query: 204 DPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLC 259
R+ F W ++ ISY F IK + + F+ F R K + ++C
Sbjct: 324 RDRLRIN---RFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVC 380
Query: 260 IGNHDLF 266
+ +H F
Sbjct: 381 VEHHTFF 387
>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
isoform 3 [Homo sapiens]
Length = 2294
Score = 113 bits (283), Expect = 4e-25
Identities = 87/308 (28%), Positives = 143/308 (46%), Gaps = 62/308 (20%)
Query: 24 VRIVTMDAE-MEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTV---------- 72
V I+ ++ + +E C+ K KD+FD+V +GL E F L T+KD
Sbjct: 574 VNIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALA-TLKDNEYFFVDPDLKL 632
Query: 73 ------AWLKMDKK------------------------------------VKKQILDEKI 90
W + KK ++K IL+E++
Sbjct: 633 TKVAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERM 692
Query: 91 YCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAW 150
+C E S+LLAS A+QA+YGDY P VH + E LP RV+ ++ +E +
Sbjct: 693 HCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLS--YIKEELPKL 750
Query: 151 YAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAI--RNKKGTELLLGVDALGLHIYDPENR 208
+ + G + E E+E+LK+ Q L YGV++ + K T +LLGV + G+ +++ N
Sbjct: 751 HNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNG 810
Query: 209 L-TPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNH--DL 265
+ T + FPW E + IS+S K+ T++ I F + ++ + +L LC H L
Sbjct: 811 VRTLVLRFPWRETKKISFSKKKITLQNTSDGIK-HGFQTDNSKICQYLLHLCSYQHKFQL 869
Query: 266 FMRRRKAD 273
MR R+++
Sbjct: 870 QMRARQSN 877
>gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform b
[Homo sapiens]
Length = 779
Score = 113 bits (283), Expect = 4e-25
Identities = 91/295 (30%), Positives = 134/295 (45%), Gaps = 57/295 (19%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMK--WKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVA- 73
K+ K+ R+ +DA E+ CE++ +G+ LFDLVC L L E +FGL + D+
Sbjct: 30 KKYKSAICRVTLLDAS-EYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKN 88
Query: 74 WLKMDKKVKKQILDE--------KIYCPPEASV--------------------------- 98
WL K++KKQI K Y P A +
Sbjct: 89 WLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFV 148
Query: 99 ---LLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHR 155
LL SYAVQA+ GDYD H ++++ P + L EERI + +R
Sbjct: 149 THALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTREL--------EERIMELHKTYR 200
Query: 156 GRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISF 215
G EAE+ +L+ A+ L MYGV+ ++ +G +++LGV A GL IY R+ F
Sbjct: 201 GMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRIN---RF 257
Query: 216 PWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLF 266
W +I ISY F IK + + F+ F R K + ++CI +H F
Sbjct: 258 AWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFF 312
>gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform a
[Homo sapiens]
Length = 881
Score = 113 bits (283), Expect = 4e-25
Identities = 91/295 (30%), Positives = 134/295 (45%), Gaps = 57/295 (19%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMK--WKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVA- 73
K+ K+ R+ +DA E+ CE++ +G+ LFDLVC L L E +FGL + D+
Sbjct: 92 KKYKSAICRVTLLDAS-EYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKN 150
Query: 74 WLKMDKKVKKQILDE--------KIYCPPEASV--------------------------- 98
WL K++KKQI K Y P A +
Sbjct: 151 WLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFV 210
Query: 99 ---LLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHR 155
LL SYAVQA+ GDYD H ++++ P + L EERI + +R
Sbjct: 211 THALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTREL--------EERIMELHKTYR 262
Query: 156 GRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISF 215
G EAE+ +L+ A+ L MYGV+ ++ +G +++LGV A GL IY R+ F
Sbjct: 263 GMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRIN---RF 319
Query: 216 PWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLF 266
W +I ISY F IK + + F+ F R K + ++CI +H F
Sbjct: 320 AWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFF 374
>gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis 1,
RH-linked) isoform 3 [Homo sapiens]
Length = 588
Score = 108 bits (271), Expect = 1e-23
Identities = 103/468 (22%), Positives = 190/468 (40%), Gaps = 60/468 (12%)
Query: 30 DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTV-AWLKMDKKVKKQI--- 85
D E E KG+DL VC L L E +FGL T WL K++KKQ+
Sbjct: 10 DTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGV 69
Query: 86 -----LDEKIYCPPEASV------------------------------LLASYAVQAKYG 110
+ K Y P A + LL SY +Q++ G
Sbjct: 70 PWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELG 129
Query: 111 DYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIA 170
DYDP +H +++ +L P + L EE++ + +R +A++E+L+ A
Sbjct: 130 DYDPELHGVDYVSDFKLAPNQTKEL--------EEKVMELHKSYRSMTPAQADLEFLENA 181
Query: 171 QDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEF 230
+ L MYGV+ ++ +G +++LGV + GL +Y + R+ FPW ++ ISY F
Sbjct: 182 KKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRIN---RFPWPKVLKISYKRSSF 238
Query: 231 TIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQARE 286
IK + + ++ F R K + ++C+ H F R D++ + A +
Sbjct: 239 FIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCV-EHHTFFRLTSTDTIPKSKFLALGSK 297
Query: 287 EKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEK 346
+ + + Q + A +R + + A + A T+ +
Sbjct: 298 FRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTSAPAITQ 357
Query: 347 AQITEEEA-KLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESER 405
Q+ E A+K + + + +KA + +E E + EA + +
Sbjct: 358 GQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQAEPEPTEAWKKKRERLDGENI 417
Query: 406 RAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPD 453
+ ++ + +DL +++E ++ + E+ K + M +P P P +
Sbjct: 418 YIRHSNLMLEDLDKSQEEIKKHHASISEL--KKNF--MESVPEPRPSE 461
>gi|150010540 FERM domain containing 4B [Homo sapiens]
Length = 1034
Score = 108 bits (269), Expect = 2e-23
Identities = 107/488 (21%), Positives = 211/488 (43%), Gaps = 90/488 (18%)
Query: 30 DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVA--WLKMDKKVKKQILD 87
D +E + K ++L DLV L+E +FG+ + I DT WL++D +V L
Sbjct: 68 DRRLELLVQPKLLARELLDLVASHFNLKEKEYFGITF-IDDTGQQNWLQLDHRVLDHDLP 126
Query: 88 EK-----------------------------------------IYCPPEASVLLASYAVQ 106
+K I E LA++ +Q
Sbjct: 127 KKPGPTILHFAVRFYIESISFLKDKTTVELFFLNAKACVHKGQIEVESETIFKLAAFILQ 186
Query: 107 AKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEM--WEERITAWYAEHRGRARDEAEM 164
GDY + R L P + + Q P + E+R+ Y + +G R +A +
Sbjct: 187 EAKGDYTSDENARKDLKTLPAFPTKTL---QEHPSLAYCEDRVIEHYLKIKGLTRGQAVV 243
Query: 165 EYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNIS 224
+Y+KI + L YGV+Y+A+++K+G LG+ G+ YD ++++ P+ F W ++ N+
Sbjct: 244 QYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLY 303
Query: 225 YSDKEFTIKPLD-KKIDVFK--FNSSKLRVN---------KLILQLCIGNHDLFMRRRKA 272
+ +K+F ++ D ++I V + F S L V K I + I H ++ R+++
Sbjct: 304 FREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQS 363
Query: 273 -----DSLEVQQMKAQAREEKARKQMERQRLAREKQM------------REEAERTRDEL 315
+ + ++ E ++ + L + Q +++E + ++
Sbjct: 364 KAKIPSARSLDEIAMDLTETGTQRASKLVTLEAKSQFIMASNGSLISSGSQDSEVSEEQK 423
Query: 316 ERRLLQMKEEATMANEALMRS-EETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKAT 374
++L++K++ + E L++ EE + +A++T + K E +++R T
Sbjct: 424 REKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGT 483
Query: 375 AIR-------TEEEKRLMEQKVLEAE-VLALKMAEESERRAKEADQLKQDLQEAREAERR 426
A + +EE+ L E LE+ ++ K+ E +++ A E D K ++ ++
Sbjct: 484 AFKLDDNLLPSEEDPALQE---LESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDYTD 540
Query: 427 AKQKLLEI 434
A +KL EI
Sbjct: 541 AMKKLQEI 548
>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
sapiens]
Length = 926
Score = 107 bits (268), Expect = 2e-23
Identities = 86/302 (28%), Positives = 138/302 (45%), Gaps = 58/302 (19%)
Query: 12 SSLKRKQPKTFTV-RIVTMDAEME-FNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-- 67
S L R + T V I+ +D ++ F +G+ L D+V + L L E +FGLQ
Sbjct: 18 SELARDRQHTEVVCNILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADD 77
Query: 68 IKDTVAWLKMDKKVKKQ---------------------------------------ILDE 88
D WL +K ++KQ IL
Sbjct: 78 STDNPRWLDPNKPIRKQLKRGSPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTG 137
Query: 89 KIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERIT 148
++ CP + LLAS+AVQ++ GDYD S + G+L+ +P + P+ +E+ I
Sbjct: 138 RLPCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQ--------PQDFEKEIA 189
Query: 149 AWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENR 208
+ +H G + EAE YL A+ LE+YGV + R++ E+++GV + G+ IY R
Sbjct: 190 KLHQQHIGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKNRVR 249
Query: 209 LTPKISFPWNEIRNISYSDKEFTI---KPL-DKKIDVFKFNSSKLRVNKLILQLCIGNHD 264
+ +FPW +I IS+ K+F I K L + + + FN R K + + C+ +H
Sbjct: 250 MN---TFPWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHT 306
Query: 265 LF 266
F
Sbjct: 307 FF 308
>gi|42716291 erythrocyte membrane protein band 4.1 (elliptocytosis
1, RH-linked) isoform 2 [Homo sapiens]
Length = 641
Score = 103 bits (256), Expect = 5e-22
Identities = 94/407 (23%), Positives = 164/407 (40%), Gaps = 56/407 (13%)
Query: 30 DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTV-AWLKMDKKVKKQI--- 85
D E E KG+DL VC L L E +FGL T WL K++KKQ+
Sbjct: 10 DTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGV 69
Query: 86 -----LDEKIYCPPEASV------------------------------LLASYAVQAKYG 110
+ K Y P A + LL SY +Q++ G
Sbjct: 70 PWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELG 129
Query: 111 DYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIA 170
DYDP +H +++ +L P + L EE++ + +R +A++E+L+ A
Sbjct: 130 DYDPELHGVDYVSDFKLAPNQTKEL--------EEKVMELHKSYRSMTPAQADLEFLENA 181
Query: 171 QDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEF 230
+ L MYGV+ ++ +G +++LGV + GL +Y + R+ FPW ++ ISY F
Sbjct: 182 KKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRIN---RFPWPKVLKISYKRSSF 238
Query: 231 TIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQARE 286
IK + + ++ F R K + ++C+ H F R D++ + A +
Sbjct: 239 FIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCV-EHHTFFRLTSTDTIPKSKFLALGSK 297
Query: 287 EKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEK 346
+ + + Q + A +R + + A + A T+ +
Sbjct: 298 FRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTSAPAITQ 357
Query: 347 AQITEEEA-KLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEA 392
Q+ E A+K + + + +KA + +E E + EA
Sbjct: 358 GQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQAEPEPTEA 404
>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
isoform 2 [Homo sapiens]
Length = 868
Score = 102 bits (255), Expect = 7e-22
Identities = 70/273 (25%), Positives = 125/273 (45%), Gaps = 56/273 (20%)
Query: 43 GKDLFDLVCRTLGLRETWFFGLQYTIK--DTVAWLKMDKKVKKQ---------------- 84
G+ L D+V LG+ E +FGLQ+ D+ WL+ K ++KQ
Sbjct: 51 GQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQLKGGFPCTLHFRVRFF 110
Query: 85 -----------------------ILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGF 121
I + ++ CP ++V+LASYAVQ+ +GDY+ S+H G+
Sbjct: 111 IPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGY 170
Query: 122 LAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYF 181
L+ +P + E + ++ + + +H G + EAE Y+ IA+ L+ YGV
Sbjct: 171 LSDSHFIPDQ--------NEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH 222
Query: 182 AIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTI----KPLDK 237
+ R+ +L++G+ + G+ +Y + +PW I IS+ K+F I K +
Sbjct: 223 SGRDLHNLDLMIGIASAGVAVY---RKYICTSFYPWVNILKISFKRKKFFIHQRQKQAES 279
Query: 238 KIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRR 270
+ + FN R K + + C+ +H F ++
Sbjct: 280 REHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKK 312
>gi|223941876 protein tyrosine phosphatase, non-receptor type 3
isoform 1 [Homo sapiens]
Length = 913
Score = 102 bits (255), Expect = 7e-22
Identities = 70/273 (25%), Positives = 125/273 (45%), Gaps = 56/273 (20%)
Query: 43 GKDLFDLVCRTLGLRETWFFGLQYTIK--DTVAWLKMDKKVKKQ---------------- 84
G+ L D+V LG+ E +FGLQ+ D+ WL+ K ++KQ
Sbjct: 51 GQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQLKGGFPCTLHFRVRFF 110
Query: 85 -----------------------ILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGF 121
I + ++ CP ++V+LASYAVQ+ +GDY+ S+H G+
Sbjct: 111 IPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGY 170
Query: 122 LAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYF 181
L+ +P + E + ++ + + +H G + EAE Y+ IA+ L+ YGV
Sbjct: 171 LSDSHFIPDQ--------NEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH 222
Query: 182 AIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTI----KPLDK 237
+ R+ +L++G+ + G+ +Y + +PW I IS+ K+F I K +
Sbjct: 223 SGRDLHNLDLMIGIASAGVAVY---RKYICTSFYPWVNILKISFKRKKFFIHQRQKQAES 279
Query: 238 KIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRR 270
+ + FN R K + + C+ +H F ++
Sbjct: 280 REHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKK 312
>gi|207113199 erythrocyte membrane protein band 4.1-like 2 isoform b
[Homo sapiens]
Length = 673
Score = 102 bits (255), Expect = 7e-22
Identities = 82/296 (27%), Positives = 135/296 (45%), Gaps = 59/296 (19%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMKW--KGKDLFDLVCRTLGLRETWFFGLQY-TIKDTVA 73
K+ KT ++ +D E++C+++ KG+ LFD VC L L E +FGL + +
Sbjct: 213 KKTKTVQCKVTLLDGT-EYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKN 271
Query: 74 WLKMDKKVKKQI--------LDEKIYCPPEAS---------------------------- 97
WL K++K+Q+ + K Y PP+ S
Sbjct: 272 WLDPAKEIKRQLRNLPWLFTFNVKFY-PPDPSQLTEDITRYFLCLQLRQDIASGRLPCSF 330
Query: 98 ---VLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH 154
LL SY +QA+ GDYDP H L++ + P + L EE++ + H
Sbjct: 331 VTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKEL--------EEKVAELHKTH 382
Query: 155 RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKIS 214
RG + +A+ ++L+ A+ L MYGV+ ++ +G ++ LGV A GL IY R+
Sbjct: 383 RGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRIN---R 439
Query: 215 FPWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLF 266
F W +I ISY F IK +++ F+ F R K + ++C+ +H +
Sbjct: 440 FAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFY 495
>gi|207113195 erythrocyte membrane protein band 4.1-like 2 isoform b
[Homo sapiens]
Length = 673
Score = 102 bits (255), Expect = 7e-22
Identities = 82/296 (27%), Positives = 135/296 (45%), Gaps = 59/296 (19%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMKW--KGKDLFDLVCRTLGLRETWFFGLQY-TIKDTVA 73
K+ KT ++ +D E++C+++ KG+ LFD VC L L E +FGL + +
Sbjct: 213 KKTKTVQCKVTLLDGT-EYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKN 271
Query: 74 WLKMDKKVKKQI--------LDEKIYCPPEAS---------------------------- 97
WL K++K+Q+ + K Y PP+ S
Sbjct: 272 WLDPAKEIKRQLRNLPWLFTFNVKFY-PPDPSQLTEDITRYFLCLQLRQDIASGRLPCSF 330
Query: 98 ---VLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH 154
LL SY +QA+ GDYDP H L++ + P + L EE++ + H
Sbjct: 331 VTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKEL--------EEKVAELHKTH 382
Query: 155 RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKIS 214
RG + +A+ ++L+ A+ L MYGV+ ++ +G ++ LGV A GL IY R+
Sbjct: 383 RGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRIN---R 439
Query: 215 FPWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLF 266
F W +I ISY F IK +++ F+ F R K + ++C+ +H +
Sbjct: 440 FAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFY 495
>gi|4503579 erythrocyte membrane protein band 4.1-like 2 isoform a
[Homo sapiens]
Length = 1005
Score = 102 bits (255), Expect = 7e-22
Identities = 82/296 (27%), Positives = 135/296 (45%), Gaps = 59/296 (19%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMKW--KGKDLFDLVCRTLGLRETWFFGLQY-TIKDTVA 73
K+ KT ++ +D E++C+++ KG+ LFD VC L L E +FGL + +
Sbjct: 213 KKTKTVQCKVTLLDGT-EYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKN 271
Query: 74 WLKMDKKVKKQI--------LDEKIYCPPEAS---------------------------- 97
WL K++K+Q+ + K Y PP+ S
Sbjct: 272 WLDPAKEIKRQLRNLPWLFTFNVKFY-PPDPSQLTEDITRYFLCLQLRQDIASGRLPCSF 330
Query: 98 ---VLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH 154
LL SY +QA+ GDYDP H L++ + P + L EE++ + H
Sbjct: 331 VTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKEL--------EEKVAELHKTH 382
Query: 155 RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKIS 214
RG + +A+ ++L+ A+ L MYGV+ ++ +G ++ LGV A GL IY R+
Sbjct: 383 RGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRIN---R 439
Query: 215 FPWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLF 266
F W +I ISY F IK +++ F+ F R K + ++C+ +H +
Sbjct: 440 FAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFY 495
>gi|116063562 FERM domain containing 4A [Homo sapiens]
Length = 1039
Score = 100 bits (249), Expect = 3e-21
Identities = 103/483 (21%), Positives = 198/483 (40%), Gaps = 79/483 (16%)
Query: 30 DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDT-VAWLKMDKKV------- 81
D ++E + K K+L DLV L+E +FG+ +T + + WL++D++V
Sbjct: 29 DRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPK 88
Query: 82 ----------------------------------KKQILDEKIYCPPEASVLLASYAVQA 107
K I E I E LASY +Q
Sbjct: 89 KSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQE 148
Query: 108 KYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYL 167
GD+ + R L + LP + + + E+R+ Y + G+ R +A + Y+
Sbjct: 149 AKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYC-EDRVIEHYKKLNGQTRGQAIVNYM 207
Query: 168 KIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSD 227
I + L YGV+Y+A+++K+G LG+ G+ YD +++ P+ F W ++ N+ + +
Sbjct: 208 SIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFRE 267
Query: 228 KEFTIK---PLDKKIDVFKFNSSKLRVN---------KLILQLCIGNHDLFMRRRKADS- 274
K+F+++ P + F S + V+ K I + I H ++ R+++ S
Sbjct: 268 KKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSK 327
Query: 275 ----LEVQQMKAQAREEKARKQMERQRLAREKQM------------REEAERTRDELERR 318
+ ++ E K + + + ++ +E++ ++ +
Sbjct: 328 IHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDM 387
Query: 319 LLQMKEEATMANEAL-MRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIR 377
L +K E L R EE L +A++T + E ++R TA +
Sbjct: 388 LAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFK 447
Query: 378 TEEEKRLMEQKVLEAEVLALKMA------EESERRAKEADQLKQDLQEAREAERRAKQKL 431
+E+K L + + E E L + A E + R A + + K+ ++ + + A +KL
Sbjct: 448 LDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKL 507
Query: 432 LEI 434
EI
Sbjct: 508 QEI 510
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,063,338
Number of Sequences: 37866
Number of extensions: 873807
Number of successful extensions: 20716
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 611
Number of HSP's successfully gapped in prelim test: 1063
Number of HSP's that attempted gapping in prelim test: 7236
Number of HSP's gapped (non-prelim): 7303
length of query: 549
length of database: 18,247,518
effective HSP length: 107
effective length of query: 442
effective length of database: 14,195,856
effective search space: 6274568352
effective search space used: 6274568352
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.