Guide to the Human Genome
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Name: PNPLA2 Sequence: fasta or formatted (504aa) NCBI GI: 32698724
Description:

patatin-like phospholipase domain containing 2

Referenced in:

Adipose Tissue
Lipid Metabolism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.3         47           2
 C cysteine            2.4         12           1
 D aspartate           3.6         18           1
 E glutamate           6.3         32           2
 F phenylalanine       3.4         17           1
 G glycine             6.3         32           2
 H histidine           2.4         12           1
 I isoleucine          4.2         21           2
 K lysine              3.0         15           1
 L leucine            14.3         72           3
 M methionine          1.8          9           2
 N asparagine          4.0         20           2
 P proline             9.1         46           2
 Q glutamine           3.4         17           1
 R arginine            6.5         33           2
 S serine              6.9         35           2
 T threonine           4.0         20           2
 V valine              5.8         29           1
 W tryptophan          1.0          5           1
 Y tyrosine            2.4         12           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   patatin-like phospholipase domain containing 2 [Homo... 
PNPLA3                0.320   patatin-like phospholipase domain containing 3 [Homo...
LOC100293124          0.295   PREDICTED: similar to patatin-like phospholipase do...
PNPLA5                0.244   patatin-like phospholipase domain containing 5 [Homo...
PNPLA1                0.201   patatin-like phospholipase domain containing 1 isof...
PNPLA1                0.150   patatin-like phospholipase domain containing 1 isof...
PNPLA4                0.148   patatin-like phospholipase domain containing 4 [Hom...
PNPLA4                0.148   patatin-like phospholipase domain containing 4 [Homo...
PNPLA1                0.143   patatin-like phospholipase domain containing 1 isof...
RAPGEF3               0.015   Rap guanine nucleotide exchange factor 3 isoform a ...
MNT                   0.012   MAX binding protein 
WNK2                  0.011   WNK lysine deficient protein kinase 2 
C15orf39              0.011   hypothetical protein LOC56905 
RAPGEF3               0.010   Rap guanine nucleotide exchange factor 3 isoform b ...
RAPGEF3               0.010   Rap guanine nucleotide exchange factor 3 isoform b [...
BAT2                  0.010   HLA-B associated transcript-2 
HS3ST6                0.010   heparan sulfate (glucosamine) 3-O-sulfotransferase ...
SHANK3                0.009   SH3 and multiple ankyrin repeat domains 3 
ZFPM1                 0.009   zinc finger protein, multitype 1 
POU6F1                0.009   POU class 6 homeobox 1 
DMRTA2                0.009   DMRT-like family A2 
GGN                   0.009   gametogenetin 
RERE                  0.008   atrophin-1 like protein isoform b 
RERE                  0.008   atrophin-1 like protein isoform a 
RERE                  0.008   atrophin-1 like protein isoform a 
LHX3                  0.008   LIM homeobox protein 3 isoform a 
LHX3                  0.008   LIM homeobox protein 3 isoform b 
BZRAP1                0.008   peripheral benzodiazepine receptor-associated prote...
CDK5RAP1              0.008   CDK5 regulatory subunit associated protein 1 isoform...
CDK5RAP1              0.008   CDK5 regulatory subunit associated protein 1 isoform...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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