Guide to the Human Genome
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Name: PNPLA3 Sequence: fasta or formatted (481aa) NCBI GI: 17196626
Description:

patatin-like phospholipase domain containing 3

Referenced in:

Adipose Tissue
Lipid Metabolism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         30           2
 C cysteine            3.7         18           1
 D aspartate           5.2         25           2
 E glutamate           4.8         23           2
 F phenylalanine       4.6         22           2
 G glycine             6.7         32           2
 H histidine           1.7          8           1
 I isoleucine          4.6         22           1
 K lysine              4.0         19           1
 L leucine            13.1         63           2
 M methionine          2.5         12           1
 N asparagine          2.5         12           1
 P proline             7.3         35           2
 Q glutamine           2.5         12           2
 R arginine            5.4         26           1
 S serine             10.6         51           3
 T threonine           4.2         20           2
 V valine              6.9         33           2
 W tryptophan          1.7          8           1
 Y tyrosine            2.1         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   patatin-like phospholipase domain containing 3 [Homo... 
PNPLA2                0.333   patatin-like phospholipase domain containing 2 [Homo...
PNPLA5                0.268   patatin-like phospholipase domain containing 5 [Homo...
PNPLA1                0.174   patatin-like phospholipase domain containing 1 isof...
PNPLA4                0.142   patatin-like phospholipase domain containing 4 [Hom...
PNPLA4                0.142   patatin-like phospholipase domain containing 4 [Homo...
PNPLA1                0.121   patatin-like phospholipase domain containing 1 isof...
PNPLA1                0.112   patatin-like phospholipase domain containing 1 isof...
LOC100293124          0.052   PREDICTED: similar to patatin-like phospholipase do...
TXNRD2                0.012   thioredoxin reductase 2 precursor 
TXNRD1                0.009   thioredoxin reductase 1 isoform 2 
TXNRD1                0.009   thioredoxin reductase 1 isoform 3 
TXNRD1                0.009   thioredoxin reductase 1 isoform 1 
TXNRD1                0.009   thioredoxin reductase 1 isoform 2 
TXNRD1                0.009   thioredoxin reductase 1 isoform 2 
LELP1                 0.007   late cornified envelope-like proline-rich 1 
HAL                   0.005   histidine ammonia-lyase 
MAP7D3                0.005   MAP7 domain containing 3 
BAG3                  0.005   BCL2-associated athanogene 3 
MUC5AC                0.004   mucin 5AC 
MUC5B                 0.004   mucin 5, subtype B, tracheobronchial 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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