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Search of human proteins with 32451486
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens]
(590 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens] 1163 0.0
gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens] 1163 0.0
gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens] 1163 0.0
gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens] 1140 0.0
gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens] 1060 0.0
gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens] 1052 0.0
gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens] 921 0.0
gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens] 921 0.0
gi|4506467 radixin [Homo sapiens] 501 e-142
gi|4505257 moesin [Homo sapiens] 496 e-140
gi|161702986 ezrin [Homo sapiens] 489 e-138
gi|21614499 ezrin [Homo sapiens] 489 e-138
gi|32967268 neurofibromin 2 isoform 8 [Homo sapiens] 303 2e-82
gi|150010540 FERM domain containing 4B [Homo sapiens] 150 2e-36
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 142 9e-34
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i... 142 9e-34
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is... 142 9e-34
gi|116063562 FERM domain containing 4A [Homo sapiens] 142 1e-33
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i... 140 3e-33
gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform... 139 7e-33
gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform... 139 7e-33
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho... 137 2e-32
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i... 135 1e-31
gi|223941876 protein tyrosine phosphatase, non-receptor type 3 i... 135 1e-31
gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo s... 134 2e-31
gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis... 132 9e-31
gi|207113199 erythrocyte membrane protein band 4.1-like 2 isofor... 128 1e-29
gi|207113195 erythrocyte membrane protein band 4.1-like 2 isofor... 128 1e-29
gi|4503579 erythrocyte membrane protein band 4.1-like 2 isoform ... 128 1e-29
gi|42716291 erythrocyte membrane protein band 4.1 (elliptocytosi... 126 5e-29
>gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 1163 bits (3008), Expect = 0.0
Identities = 590/590 (100%), Positives = 590/590 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
Query: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG
Sbjct: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
Query: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC
Sbjct: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
Query: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL
Sbjct: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
Query: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE
Sbjct: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
Query: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT
Sbjct: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
Query: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN
Sbjct: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
Query: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 590
ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI
Sbjct: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 590
>gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 1163 bits (3008), Expect = 0.0
Identities = 590/590 (100%), Positives = 590/590 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
Query: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG
Sbjct: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
Query: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC
Sbjct: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
Query: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL
Sbjct: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
Query: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE
Sbjct: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
Query: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT
Sbjct: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
Query: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN
Sbjct: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
Query: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 590
ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI
Sbjct: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 590
>gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 1163 bits (3008), Expect = 0.0
Identities = 590/590 (100%), Positives = 590/590 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
Query: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG
Sbjct: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
Query: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC
Sbjct: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
Query: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL
Sbjct: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
Query: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE
Sbjct: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
Query: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT
Sbjct: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
Query: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN
Sbjct: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
Query: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 590
ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI
Sbjct: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 590
>gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens]
Length = 595
Score = 1140 bits (2948), Expect = 0.0
Identities = 580/586 (98%), Positives = 581/586 (99%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
Query: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG
Sbjct: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
Query: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC
Sbjct: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
Query: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL
Sbjct: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
Query: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE
Sbjct: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
Query: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT
Sbjct: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
Query: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN
Sbjct: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
Query: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRR 586
ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKK Q +
Sbjct: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKLTLQSAK 586
>gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens]
Length = 549
Score = 1060 bits (2741), Expect = 0.0
Identities = 549/590 (93%), Positives = 549/590 (93%), Gaps = 41/590 (6%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKKV
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKV--------------------------------------- 81
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
KKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT
Sbjct: 82 --KKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 139
Query: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG
Sbjct: 140 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 199
Query: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC
Sbjct: 200 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 259
Query: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL
Sbjct: 260 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 319
Query: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE
Sbjct: 320 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 379
Query: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT
Sbjct: 380 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 439
Query: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN
Sbjct: 440 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 499
Query: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 590
ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI
Sbjct: 500 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 549
>gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens]
Length = 548
Score = 1052 bits (2721), Expect = 0.0
Identities = 548/590 (92%), Positives = 548/590 (92%), Gaps = 42/590 (7%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCE
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCE---------------------- 38
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
VLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 39 --------------------VLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 78
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 180
QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT
Sbjct: 79 QVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMT 138
Query: 181 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 240
PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG
Sbjct: 139 PEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALG 198
Query: 241 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 300
LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC
Sbjct: 199 LHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLC 258
Query: 301 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 360
IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL
Sbjct: 259 IGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRL 318
Query: 361 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 420
LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE
Sbjct: 319 LQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTE 378
Query: 421 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 480
EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT
Sbjct: 379 EEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPT 438
Query: 481 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 540
YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN
Sbjct: 439 YPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLN 498
Query: 541 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 590
ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI
Sbjct: 499 ELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI 548
>gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 921 bits (2380), Expect = 0.0
Identities = 474/499 (94%), Positives = 481/499 (96%)
Query: 92 VTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKYG 151
++F L + P+ +V + F +VKKQILDEKIYCPPEASVLLASYAVQAKYG
Sbjct: 9 MSFSSLKRKQPKTFTVRIVTMDAEMEFNCEVKKQILDEKIYCPPEASVLLASYAVQAKYG 68
Query: 152 DYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIA 211
DYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIA
Sbjct: 69 DYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIA 128
Query: 212 QDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEF 271
QDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEF
Sbjct: 129 QDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEF 188
Query: 272 TIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKAR 331
TIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKAR
Sbjct: 189 TIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKAR 248
Query: 332 KQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQIT 391
KQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQIT
Sbjct: 249 KQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQIT 308
Query: 392 EEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEA 451
EEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEA
Sbjct: 309 EEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEA 368
Query: 452 DQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKD 511
DQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKD
Sbjct: 369 DQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKD 428
Query: 512 TDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGS 571
TDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGS
Sbjct: 429 TDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGS 488
Query: 572 SKHNTIKKPQAQGRRPICI 590
SKHNTIKKPQAQGRRPICI
Sbjct: 489 SKHNTIKKPQAQGRRPICI 507
>gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 921 bits (2380), Expect = 0.0
Identities = 474/499 (94%), Positives = 481/499 (96%)
Query: 92 VTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKYG 151
++F L + P+ +V + F +VKKQILDEKIYCPPEASVLLASYAVQAKYG
Sbjct: 9 MSFSSLKRKQPKTFTVRIVTMDAEMEFNCEVKKQILDEKIYCPPEASVLLASYAVQAKYG 68
Query: 152 DYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIA 211
DYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIA
Sbjct: 69 DYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIA 128
Query: 212 QDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEF 271
QDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEF
Sbjct: 129 QDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEF 188
Query: 272 TIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKAR 331
TIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKAR
Sbjct: 189 TIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKAR 248
Query: 332 KQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQIT 391
KQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQIT
Sbjct: 249 KQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQIT 308
Query: 392 EEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEA 451
EEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEA
Sbjct: 309 EEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEA 368
Query: 452 DQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKD 511
DQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKD
Sbjct: 369 DQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKD 428
Query: 512 TDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGS 571
TDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGS
Sbjct: 429 TDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGS 488
Query: 572 SKHNTIKKPQAQGRRPICI 590
SKHNTIKKPQAQGRRPICI
Sbjct: 489 SKHNTIKKPQAQGRRPICI 507
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 501 bits (1290), Expect = e-142
Identities = 260/569 (45%), Positives = 376/569 (66%), Gaps = 11/569 (1%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-IKDTVAWLKM 77
PK VR+ TMDAE+EF + GK LFD V +T+GLRE WFFGLQY K WLK+
Sbjct: 2 PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKL 61
Query: 78 DKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEA 137
+KKV DV KE P+ F F AKF+PE+ EEL+QEITQ LFFLQVK+ IL+++IYCPPE
Sbjct: 62 NKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPET 121
Query: 138 SVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRG 197
+VLLASYAVQAKYGDY+ +HK G+LA + LLP+RV+ +++T E WEERI W+ EHRG
Sbjct: 122 AVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRG 181
Query: 198 RARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFP 257
R+++ MEYLKIAQDLEMYGVNYF I+NKKGTEL LGVDALGL+IY+ +++LTPKI FP
Sbjct: 182 MLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFP 241
Query: 258 WNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLE 317
W+EIRNIS++DK+F IKP+DKK F F + +LR+NK IL LC+GNH+L+MRRRK D++E
Sbjct: 242 WSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIE 301
Query: 318 VQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRS 377
VQQMKAQAREEK +KQ+ER +L EK+ RE AE+ ++ +ER ++ E E +++
Sbjct: 302 VQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKA 361
Query: 378 EETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIK----ATAIRTEEEKRLMEQKVLEA 433
++ + KA ++E K ++A E+E + + A A + ++ + EQ E
Sbjct: 362 QKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAEL 421
Query: 434 EVLALKMA---EESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAP 490
K+A E +++ +EA + + A+E + K++L + + P PP P+ P
Sbjct: 422 AEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPP 481
Query: 491 LPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALK 550
+ + S + + + ++ E+E+V +K++ +++QL L +E+ +
Sbjct: 482 TENEHDEHDENNAEASAELSNEGV--MNHRSEEERVTETQKNERVKKQLQALSSELAQAR 539
Query: 551 LKERETALDILHNENSDRGGSSKHNTIKK 579
+ ++T D+LH EN + G K+ T+++
Sbjct: 540 DETKKTQNDVLHAENV-KAGRDKYKTLRQ 567
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 496 bits (1277), Expect = e-140
Identities = 268/569 (47%), Positives = 378/569 (66%), Gaps = 17/569 (2%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-IKDTVAWLKM 77
PKT +VR+ TMDAE+EF + GK LFD V +T+GLRE WFFGLQY K WLK+
Sbjct: 2 PKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKL 61
Query: 78 DKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEA 137
+KKV DV KE P+ F F AKFYPE+ EEL+Q+ITQ LFFLQVK+ IL++ IYCPPE
Sbjct: 62 NKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPET 121
Query: 138 SVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRG 197
+VLLASYAVQ+KYGD++ VHK G+LA ++LLP+RV+ +++ + WEERI W+ EHRG
Sbjct: 122 AVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRG 181
Query: 198 RARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFP 257
R++A +EYLKIAQDLEMYGVNYF+I+NKKG+EL LGVDALGL+IY+ +RLTPKI FP
Sbjct: 182 MLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFP 241
Query: 258 WNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLE 317
W+EIRNIS++DK+F IKP+DKK F F + +LR+NK IL LC+GNH+L+MRRRK D++E
Sbjct: 242 WSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIE 301
Query: 318 VQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELER-------RLLQMKEEATMA 370
VQQMKAQAREEK +KQMER L EK+ RE AE+ ++++ER RL Q++E+ A
Sbjct: 302 VQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKA 361
Query: 371 NEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKV 430
+ L A L ++ + + EA+ LA++ EAE+ + A + ++K+ EQ
Sbjct: 362 QQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKE---ALLQASRDQKKTQEQLA 418
Query: 431 LEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAP 490
LE L ++++ R K+ + + Q+A+ + ++ E+ T + P + PA
Sbjct: 419 LEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAE-PAE 477
Query: 491 LPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALK 550
D N G S D + M + E+E+ EK++ +Q+ L L +E+ +
Sbjct: 478 NEQDEQDEN--GAEASADLRADAMAK--DRSEEERTTEAEKNERVQKHLKALTSELANAR 533
Query: 551 LKERETALDILHNENSDRGGSSKHNTIKK 579
+ ++TA D++H EN R G K+ T+++
Sbjct: 534 DESKKTANDMIHAENM-RLGRDKYKTLRQ 561
Score = 33.5 bits (75), Expect = 0.56
Identities = 35/158 (22%), Positives = 70/158 (44%), Gaps = 14/158 (8%)
Query: 315 SLEVQQMKAQ------AREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEAT 368
+LE+ ++ A+ AR++K + +E Q+ A+ ++E+ E+TR EL+ +
Sbjct: 418 ALEMAELTARISQLEMARQKKESEAVEWQQKAQ--MVQEDLEKTRAELKTAMSTPHVAEP 475
Query: 369 MANEALMRSEE----TADLLAEKA--QITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEE 422
NE + E +ADL A+ +EEE A+K ++ ++ + + +E
Sbjct: 476 AENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDE 535
Query: 423 KRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQE 460
+ ++ AE + L + R KQ + E
Sbjct: 536 SKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDE 573
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 489 bits (1260), Expect = e-138
Identities = 268/576 (46%), Positives = 379/576 (65%), Gaps = 22/576 (3%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTI-KDTVAWLKM 77
PK VR+ TMDAE+EF + GK LFD V +T+GLRE W+FGL Y K WLK+
Sbjct: 2 PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61
Query: 78 DKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEA 137
DKKV +V KE P+ F F AKFYPE+ EEL+Q+ITQ LFFLQVK+ IL ++IYCPPE
Sbjct: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121
Query: 138 SVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRG 197
+VLL SYAVQAK+GDY+ VHK G+L+ E L+P+RV++ +++T + WE+RI W+AEHRG
Sbjct: 122 AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRG 181
Query: 198 RARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFP 257
+D A +EYLKIAQDLEMYG+NYF I+NKKGT+L LGVDALGL+IY+ +++LTPKI FP
Sbjct: 182 MLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP 241
Query: 258 WNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLE 317
W+EIRNIS++DK+F IKP+DKK F F + +LR+NK ILQLC+GNH+L+MRRRK D++E
Sbjct: 242 WSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIE 301
Query: 318 VQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRS 377
VQQMKAQAREEK +KQ+ERQ+L EK+ RE ER ++++ R ++ E ++
Sbjct: 302 VQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKA 361
Query: 378 EETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEE-KRLMEQKVLEAEVL 436
E ++A EEE K +A E + ++ + A+R +EE +R ++ E L
Sbjct: 362 ERELSEQIQRALQLEEERK----RAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQL 417
Query: 437 ALKMAEESERRA--KEADQLKQDLQEAREAERRAKQKLLE-IATKPTYPPMNPIPAPLPP 493
A ++AE + + A +EA + K+D E E + RAK+ + + TK + P P PP
Sbjct: 418 AAELAEYTAKIALLEEARRRKED--EVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPP 475
Query: 494 DI--PSFNLIGDSLSFDFKDTD--MKRLSME------IEKEKVEYMEKSKHLQEQLNELK 543
+ P + +SL + + LS E E++++ EK++ +Q QL L
Sbjct: 476 PVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLS 535
Query: 544 TEIEALKLKERETALDILHNENSDRGGSSKHNTIKK 579
+E+ + + + T DI+HNEN R G K+ T+++
Sbjct: 536 SELSQARDENKRTHNDIIHNENM-RQGRDKYKTLRQ 570
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 489 bits (1260), Expect = e-138
Identities = 268/576 (46%), Positives = 379/576 (65%), Gaps = 22/576 (3%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTI-KDTVAWLKM 77
PK VR+ TMDAE+EF + GK LFD V +T+GLRE W+FGL Y K WLK+
Sbjct: 2 PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61
Query: 78 DKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEA 137
DKKV +V KE P+ F F AKFYPE+ EEL+Q+ITQ LFFLQVK+ IL ++IYCPPE
Sbjct: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121
Query: 138 SVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRG 197
+VLL SYAVQAK+GDY+ VHK G+L+ E L+P+RV++ +++T + WE+RI W+AEHRG
Sbjct: 122 AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRG 181
Query: 198 RARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFP 257
+D A +EYLKIAQDLEMYG+NYF I+NKKGT+L LGVDALGL+IY+ +++LTPKI FP
Sbjct: 182 MLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP 241
Query: 258 WNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLE 317
W+EIRNIS++DK+F IKP+DKK F F + +LR+NK ILQLC+GNH+L+MRRRK D++E
Sbjct: 242 WSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIE 301
Query: 318 VQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRS 377
VQQMKAQAREEK +KQ+ERQ+L EK+ RE ER ++++ R ++ E ++
Sbjct: 302 VQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKA 361
Query: 378 EETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEE-KRLMEQKVLEAEVL 436
E ++A EEE K +A E + ++ + A+R +EE +R ++ E L
Sbjct: 362 ERELSEQIQRALQLEEERK----RAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQL 417
Query: 437 ALKMAEESERRA--KEADQLKQDLQEAREAERRAKQKLLE-IATKPTYPPMNPIPAPLPP 493
A ++AE + + A +EA + K+D E E + RAK+ + + TK + P P PP
Sbjct: 418 AAELAEYTAKIALLEEARRRKED--EVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPP 475
Query: 494 DI--PSFNLIGDSLSFDFKDTD--MKRLSME------IEKEKVEYMEKSKHLQEQLNELK 543
+ P + +SL + + LS E E++++ EK++ +Q QL L
Sbjct: 476 PVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLS 535
Query: 544 TEIEALKLKERETALDILHNENSDRGGSSKHNTIKK 579
+E+ + + + T DI+HNEN R G K+ T+++
Sbjct: 536 SELSQARDENKRTHNDIIHNENM-RQGRDKYKTLRQ 570
>gi|32967268 neurofibromin 2 isoform 8 [Homo sapiens]
Length = 165
Score = 303 bits (777), Expect = 2e-82
Identities = 149/149 (100%), Positives = 149/149 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
QVKKQILDEKIYCPPEASVLLASYAVQAK
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
>gi|150010540 FERM domain containing 4B [Homo sapiens]
Length = 1034
Score = 150 bits (380), Expect = 2e-36
Identities = 123/489 (25%), Positives = 233/489 (47%), Gaps = 51/489 (10%)
Query: 30 DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVA--WLKMDKKVLDHDVS 87
D +E + K ++L DLV L+E +FG+ + I DT WL++D +VLDHD+
Sbjct: 68 DRRLELLVQPKLLARELLDLVASHFNLKEKEYFGITF-IDDTGQQNWLQLDHRVLDHDLP 126
Query: 88 KEE-PVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAV 146
K+ P HF +FY E+ L + T LFFL K + +I E LA++ +
Sbjct: 127 KKPGPTILHFAVRFYIESISF-LKDKTTVELFFLNAKACVHKGQIEVESETIFKLAAFIL 185
Query: 147 QAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEM--WEERITAWYAEHRGRARDEAE 204
Q GDY + R L P + + Q P + E+R+ Y + +G R +A
Sbjct: 186 QEAKGDYTSDENARKDLKTLPAFPTKTL---QEHPSLAYCEDRVIEHYLKIKGLTRGQAV 242
Query: 205 MEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNI 264
++Y+KI + L YGV+Y+A+++K+G LG+ G+ YD ++++ P+ F W ++ N+
Sbjct: 243 VQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENL 302
Query: 265 SYSDKEFTIKPLD-KKIDVFK--FNSSKLRVN---------KLILQLCIGNHDLFMRRRK 312
+ +K+F ++ D ++I V + F S L V K I + I H ++ R++
Sbjct: 303 YFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQ 362
Query: 313 A-----DSLEVQQMKAQAREEKARKQMERQRLAREKQM------------REEAERTRDE 355
+ + + ++ E ++ + L + Q +++E + ++
Sbjct: 363 SKAKIPSARSLDEIAMDLTETGTQRASKLVTLEAKSQFIMASNGSLISSGSQDSEVSEEQ 422
Query: 356 LERRLLQMKEEATMANEALMRS-EETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKA 414
++L++K++ + E L++ EE + +A++T + K E +++R
Sbjct: 423 KREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVG 482
Query: 415 TAIR-------TEEEKRLMEQKVLEAE-VLALKMAEESERRAKEADQLKQDLQEAREAER 466
TA + +EE+ L E LE+ ++ K+ E +++ A E D K ++ ++
Sbjct: 483 TAFKLDDNLLPSEEDPALQE---LESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDYT 539
Query: 467 RAKQKLLEI 475
A +KL EI
Sbjct: 540 DAMKKLQEI 548
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 142 bits (358), Expect = 9e-34
Identities = 111/365 (30%), Positives = 183/365 (50%), Gaps = 30/365 (8%)
Query: 24 VRIVTMDAE-MEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVAW-----LKM 77
V I+ ++ + +E C+ K KD+FD+V +GL E F L T+KD + LK+
Sbjct: 574 VNIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALA-TLKDNEYFFVDPDLKL 632
Query: 78 DKKVLDHDVSKEEP---------VTFHFLAKFYPENAEEELVQE-ITQHLFFLQVKKQIL 127
K + + KEEP T F KF+ ++ L+Q +T H ++LQ++K IL
Sbjct: 633 TK--VAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVS--LIQHTLTCHQYYLQLRKDIL 688
Query: 128 DEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEER 187
+E+++C E S+LLAS A+QA+YGDY P VH + E LP RV+ ++ +E
Sbjct: 689 EERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLS--YIKEE 746
Query: 188 ITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAI--RNKKGTELLLGVDALGLHIYD 245
+ + + G + E E+E+LK+ Q L YGV++ + K T +LLGV + G+ +++
Sbjct: 747 LPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFE 806
Query: 246 PENRL-TPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNH 304
N + T + FPW E + IS+S K+ T++ I F + ++ + +L LC H
Sbjct: 807 VHNGVRTLVLRFPWRETKKISFSKKKITLQNTSDGIK-HGFQTDNSKICQYLLHLCSYQH 865
Query: 305 DLFMRRRKADSLEVQQMKAQAREEKARKQMERQR---LAREKQMREEAERTRDELERRLL 361
++ R S + Q +A Q E R + R A T ++L R L
Sbjct: 866 KFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLNKLAVRPL 925
Query: 362 QMKEE 366
++ E
Sbjct: 926 SVQAE 930
>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
Length = 2485
Score = 142 bits (358), Expect = 9e-34
Identities = 111/365 (30%), Positives = 183/365 (50%), Gaps = 30/365 (8%)
Query: 24 VRIVTMDAE-MEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVAW-----LKM 77
V I+ ++ + +E C+ K KD+FD+V +GL E F L T+KD + LK+
Sbjct: 574 VNIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALA-TLKDNEYFFVDPDLKL 632
Query: 78 DKKVLDHDVSKEEP---------VTFHFLAKFYPENAEEELVQE-ITQHLFFLQVKKQIL 127
K + + KEEP T F KF+ ++ L+Q +T H ++LQ++K IL
Sbjct: 633 TK--VAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVS--LIQHTLTCHQYYLQLRKDIL 688
Query: 128 DEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEER 187
+E+++C E S+LLAS A+QA+YGDY P VH + E LP RV+ ++ +E
Sbjct: 689 EERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLS--YIKEE 746
Query: 188 ITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAI--RNKKGTELLLGVDALGLHIYD 245
+ + + G + E E+E+LK+ Q L YGV++ + K T +LLGV + G+ +++
Sbjct: 747 LPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFE 806
Query: 246 PENRL-TPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNH 304
N + T + FPW E + IS+S K+ T++ I F + ++ + +L LC H
Sbjct: 807 VHNGVRTLVLRFPWRETKKISFSKKKITLQNTSDGIK-HGFQTDNSKICQYLLHLCSYQH 865
Query: 305 DLFMRRRKADSLEVQQMKAQAREEKARKQMERQR---LAREKQMREEAERTRDELERRLL 361
++ R S + Q +A Q E R + R A T ++L R L
Sbjct: 866 KFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLNKLAVRPL 925
Query: 362 QMKEE 366
++ E
Sbjct: 926 SVQAE 930
>gi|5453992 protein tyrosine phosphatase, non-receptor type 13
isoform 2 [Homo sapiens]
Length = 2466
Score = 142 bits (358), Expect = 9e-34
Identities = 111/365 (30%), Positives = 183/365 (50%), Gaps = 30/365 (8%)
Query: 24 VRIVTMDAE-MEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVAW-----LKM 77
V I+ ++ + +E C+ K KD+FD+V +GL E F L T+KD + LK+
Sbjct: 574 VNIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALA-TLKDNEYFFVDPDLKL 632
Query: 78 DKKVLDHDVSKEEP---------VTFHFLAKFYPENAEEELVQE-ITQHLFFLQVKKQIL 127
K + + KEEP T F KF+ ++ L+Q +T H ++LQ++K IL
Sbjct: 633 TK--VAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVS--LIQHTLTCHQYYLQLRKDIL 688
Query: 128 DEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEER 187
+E+++C E S+LLAS A+QA+YGDY P VH + E LP RV+ ++ +E
Sbjct: 689 EERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLS--YIKEE 746
Query: 188 ITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAI--RNKKGTELLLGVDALGLHIYD 245
+ + + G + E E+E+LK+ Q L YGV++ + K T +LLGV + G+ +++
Sbjct: 747 LPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFE 806
Query: 246 PENRL-TPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNH 304
N + T + FPW E + IS+S K+ T++ I F + ++ + +L LC H
Sbjct: 807 VHNGVRTLVLRFPWRETKKISFSKKKITLQNTSDGIK-HGFQTDNSKICQYLLHLCSYQH 865
Query: 305 DLFMRRRKADSLEVQQMKAQAREEKARKQMERQR---LAREKQMREEAERTRDELERRLL 361
++ R S + Q +A Q E R + R A T ++L R L
Sbjct: 866 KFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLNKLAVRPL 925
Query: 362 QMKEE 366
++ E
Sbjct: 926 SVQAE 930
>gi|116063562 FERM domain containing 4A [Homo sapiens]
Length = 1039
Score = 142 bits (357), Expect = 1e-33
Identities = 119/484 (24%), Positives = 219/484 (45%), Gaps = 40/484 (8%)
Query: 30 DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDT-VAWLKMDKKVLDHDVSK 88
D ++E + K K+L DLV L+E +FG+ +T + + WL++D++VL+HD K
Sbjct: 29 DRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPK 88
Query: 89 EE-PVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQ 147
+ PV +F +FY E+ L T LFFL K I E I E LASY +Q
Sbjct: 89 KSGPVVLYFCVRFYIESISY-LKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQ 147
Query: 148 AKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEY 207
GD+ + R L + LP + + + E+R+ Y + G+ R +A + Y
Sbjct: 148 EAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYC-EDRVIEHYKKLNGQTRGQAIVNY 206
Query: 208 LKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYS 267
+ I + L YGV+Y+A+++K+G LG+ G+ YD +++ P+ F W ++ N+ +
Sbjct: 207 MSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFR 266
Query: 268 DKEFTIK---PLDKKIDVFKFNSSKLRVN---------KLILQLCIGNHDLFMRRRKADS 315
+K+F+++ P + F S + V+ K I + I H ++ R+++ S
Sbjct: 267 EKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKS 326
Query: 316 -----LEVQQMKAQAREEKARKQMERQRLAREKQM------------REEAERTRDELER 358
+ ++ E K + + + ++ +E++ ++ +
Sbjct: 327 KIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKD 386
Query: 359 RLLQMKEEATMANEAL-MRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAI 417
L +K E L R EE L +A++T + E ++R TA
Sbjct: 387 MLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAF 446
Query: 418 RTEEEKRLMEQKVLEAEVLALKMA------EESERRAKEADQLKQDLQEAREAERRAKQK 471
+ +E+K L + + E E L + A E + R A + + K+ ++ + + A +K
Sbjct: 447 KLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKK 506
Query: 472 LLEI 475
L EI
Sbjct: 507 LQEI 510
>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
isoform 3 [Homo sapiens]
Length = 2294
Score = 140 bits (353), Expect = 3e-33
Identities = 101/312 (32%), Positives = 167/312 (53%), Gaps = 29/312 (9%)
Query: 24 VRIVTMDAE-MEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVAW-----LKM 77
V I+ ++ + +E C+ K KD+FD+V +GL E F L T+KD + LK+
Sbjct: 574 VNIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALA-TLKDNEYFFVDPDLKL 632
Query: 78 DKKVLDHDVSKEEP---------VTFHFLAKFYPENAEEELVQE-ITQHLFFLQVKKQIL 127
K + + KEEP T F KF+ ++ L+Q +T H ++LQ++K IL
Sbjct: 633 TK--VAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVS--LIQHTLTCHQYYLQLRKDIL 688
Query: 128 DEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEER 187
+E+++C E S+LLAS A+QA+YGDY P VH + E LP RV+ ++ +E
Sbjct: 689 EERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLS--YIKEE 746
Query: 188 ITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAI--RNKKGTELLLGVDALGLHIYD 245
+ + + G + E E+E+LK+ Q L YGV++ + K T +LLGV + G+ +++
Sbjct: 747 LPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFE 806
Query: 246 PENRL-TPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNH 304
N + T + FPW E + IS+S K+ T++ I F + ++ + +L LC H
Sbjct: 807 VHNGVRTLVLRFPWRETKKISFSKKKITLQNTSDGIK-HGFQTDNSKICQYLLHLCSYQH 865
Query: 305 --DLFMRRRKAD 314
L MR R+++
Sbjct: 866 KFQLQMRARQSN 877
>gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform b
[Homo sapiens]
Length = 779
Score = 139 bits (350), Expect = 7e-33
Identities = 97/298 (32%), Positives = 151/298 (50%), Gaps = 22/298 (7%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMK--WKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVA- 73
K+ K+ R+ +DA E+ CE++ +G+ LFDLVC L L E +FGL + D+
Sbjct: 30 KKYKSAICRVTLLDAS-EYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKN 88
Query: 74 WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYC 133
WL K++ + P F F KFYP + + L ++IT++ LQ++ I+ ++ C
Sbjct: 89 WLDPSKEIKKQ--IRSSPWNFAFTVKFYPPDPAQ-LTEDITRYYLCLQLRADIITGRLPC 145
Query: 134 PPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYA 193
LL SYAVQA+ GDYD H ++++ P + L EERI +
Sbjct: 146 SFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTREL--------EERIMELHK 197
Query: 194 EHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPK 253
+RG EAE+ +L+ A+ L MYGV+ ++ +G +++LGV A GL IY R+
Sbjct: 198 TYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRIN-- 255
Query: 254 ISFPWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLF 307
F W +I ISY F IK + + F+ F R K + ++CI +H F
Sbjct: 256 -RFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFF 312
>gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform a
[Homo sapiens]
Length = 881
Score = 139 bits (350), Expect = 7e-33
Identities = 97/298 (32%), Positives = 151/298 (50%), Gaps = 22/298 (7%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMK--WKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVA- 73
K+ K+ R+ +DA E+ CE++ +G+ LFDLVC L L E +FGL + D+
Sbjct: 92 KKYKSAICRVTLLDAS-EYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKN 150
Query: 74 WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYC 133
WL K++ + P F F KFYP + + L ++IT++ LQ++ I+ ++ C
Sbjct: 151 WLDPSKEIKKQ--IRSSPWNFAFTVKFYPPDPAQ-LTEDITRYYLCLQLRADIITGRLPC 207
Query: 134 PPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYA 193
LL SYAVQA+ GDYD H ++++ P + L EERI +
Sbjct: 208 SFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTREL--------EERIMELHK 259
Query: 194 EHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPK 253
+RG EAE+ +L+ A+ L MYGV+ ++ +G +++LGV A GL IY R+
Sbjct: 260 TYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRIN-- 317
Query: 254 ISFPWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLF 307
F W +I ISY F IK + + F+ F R K + ++CI +H F
Sbjct: 318 -RFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFF 374
>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
sapiens]
Length = 926
Score = 137 bits (346), Expect = 2e-32
Identities = 95/304 (31%), Positives = 159/304 (52%), Gaps = 21/304 (6%)
Query: 12 SSLKRKQPKTFTV-RIVTMDAEME-FNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-- 67
S L R + T V I+ +D ++ F +G+ L D+V + L L E +FGLQ
Sbjct: 18 SELARDRQHTEVVCNILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADD 77
Query: 68 IKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQIL 127
D WL +K + + + P + +F KF+ + + L +E T++ +FLQ+K+ IL
Sbjct: 78 STDNPRWLDPNKPIRKQ-LKRGSPYSLNFRVKFFVSDPNK-LQEEYTRYQYFLQIKQDIL 135
Query: 128 DEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEER 187
++ CP + LLAS+AVQ++ GDYD S + G+L+ +P + P+ +E+
Sbjct: 136 TGRLPCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQ--------PQDFEKE 187
Query: 188 ITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPE 247
I + +H G + EAE YL A+ LE+YGV + R++ E+++GV + G+ IY
Sbjct: 188 IAKLHQQHIGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKNR 247
Query: 248 NRLTPKISFPWNEIRNISYSDKEFTI---KPL-DKKIDVFKFNSSKLRVNKLILQLCIGN 303
R+ +FPW +I IS+ K+F I K L + + + FN R K + + C+ +
Sbjct: 248 VRMN---TFPWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEH 304
Query: 304 HDLF 307
H F
Sbjct: 305 HTFF 308
>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
isoform 2 [Homo sapiens]
Length = 868
Score = 135 bits (339), Expect = 1e-31
Identities = 83/275 (30%), Positives = 144/275 (52%), Gaps = 19/275 (6%)
Query: 43 GKDLFDLVCRTLGLRETWFFGLQYTIK--DTVAWLKMDKKVLDHDVSKEEPVTFHFLAKF 100
G+ L D+V LG+ E +FGLQ+ D+ WL+ K + + P T HF +F
Sbjct: 51 GQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQ-LKGGFPCTLHFRVRF 109
Query: 101 YPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKR 160
+ + L QE T+HL+FLQ+K I + ++ CP ++V+LASYAVQ+ +GDY+ S+H
Sbjct: 110 FIPDPNT-LQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHP 168
Query: 161 GFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVN 220
G+L+ +P + E + ++ + + +H G + EAE Y+ IA+ L+ YGV
Sbjct: 169 GYLSDSHFIPDQ--------NEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVE 220
Query: 221 YFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTI----KPL 276
+ R+ +L++G+ + G+ +Y + +PW I IS+ K+F I K
Sbjct: 221 LHSGRDLHNLDLMIGIASAGVAVY---RKYICTSFYPWVNILKISFKRKKFFIHQRQKQA 277
Query: 277 DKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRR 311
+ + + FN R K + + C+ +H F ++
Sbjct: 278 ESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKK 312
>gi|223941876 protein tyrosine phosphatase, non-receptor type 3
isoform 1 [Homo sapiens]
Length = 913
Score = 135 bits (339), Expect = 1e-31
Identities = 83/275 (30%), Positives = 144/275 (52%), Gaps = 19/275 (6%)
Query: 43 GKDLFDLVCRTLGLRETWFFGLQYTIK--DTVAWLKMDKKVLDHDVSKEEPVTFHFLAKF 100
G+ L D+V LG+ E +FGLQ+ D+ WL+ K + + P T HF +F
Sbjct: 51 GQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQ-LKGGFPCTLHFRVRF 109
Query: 101 YPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKR 160
+ + L QE T+HL+FLQ+K I + ++ CP ++V+LASYAVQ+ +GDY+ S+H
Sbjct: 110 FIPDPNT-LQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHP 168
Query: 161 GFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVN 220
G+L+ +P + E + ++ + + +H G + EAE Y+ IA+ L+ YGV
Sbjct: 169 GYLSDSHFIPDQ--------NEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVE 220
Query: 221 YFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTI----KPL 276
+ R+ +L++G+ + G+ +Y + +PW I IS+ K+F I K
Sbjct: 221 LHSGRDLHNLDLMIGIASAGVAVY---RKYICTSFYPWVNILKISFKRKKFFIHQRQKQA 277
Query: 277 DKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRR 311
+ + + FN R K + + C+ +H F ++
Sbjct: 278 ESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKK 312
>gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo
sapiens]
Length = 1087
Score = 134 bits (338), Expect = 2e-31
Identities = 95/310 (30%), Positives = 155/310 (50%), Gaps = 23/310 (7%)
Query: 6 ASRMSFSSLKR-KQPKTFTVRIVTMDAEMEFNC--EMKWKGKDLFDLVCRTLGLRETWFF 62
+S++S S LK K+PK+ +++ +D E+ C E + +G+ LFD VC L L E +F
Sbjct: 93 SSKLSRSPLKIVKKPKSMQCKVILLDGS-EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYF 151
Query: 63 GLQYT-IKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQ 121
GL Y ++ WL K++ + F F KFYP + + L ++IT++ LQ
Sbjct: 152 GLTYRDAENQKNWLDPAKEIKKQ--VRSGAWHFSFNVKFYPPDPAQ-LSEDITRYYLCLQ 208
Query: 122 VKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTP 181
++ I+ ++ C LL SY VQ++ GDYDP ++++ P L
Sbjct: 209 LRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHTKEL----- 263
Query: 182 EMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGL 241
E+++ + HRG EAEM +L+ A+ L MYGV+ ++ +G E++LGV A GL
Sbjct: 264 ---EDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGL 320
Query: 242 HIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLIL 297
IY R+ F W ++ ISY F IK + + F+ F R K +
Sbjct: 321 LIYRDRLRIN---RFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLW 377
Query: 298 QLCIGNHDLF 307
++C+ +H F
Sbjct: 378 KVCVEHHTFF 387
>gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis 1,
RH-linked) isoform 3 [Homo sapiens]
Length = 588
Score = 132 bits (332), Expect = 9e-31
Identities = 110/471 (23%), Positives = 207/471 (43%), Gaps = 25/471 (5%)
Query: 30 DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTV-AWLKMDKKVLDHDVSK 88
D E E KG+DL VC L L E +FGL T WL K++ +
Sbjct: 10 DTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQ--VR 67
Query: 89 EEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQA 148
P F F KFYP + + L ++IT++ LQ+++ I+ ++ C LL SY +Q+
Sbjct: 68 GVPWNFTFNVKFYPPDPAQ-LTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 126
Query: 149 KYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYL 208
+ GDYDP +H +++ +L P + L EE++ + +R +A++E+L
Sbjct: 127 ELGDYDPELHGVDYVSDFKLAPNQTKEL--------EEKVMELHKSYRSMTPAQADLEFL 178
Query: 209 KIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSD 268
+ A+ L MYGV+ ++ +G +++LGV + GL +Y + R+ FPW ++ ISY
Sbjct: 179 ENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRIN---RFPWPKVLKISYKR 235
Query: 269 KEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQ 324
F IK + + ++ F R K + ++C+ H F R D++ + A
Sbjct: 236 SSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCV-EHHTFFRLTSTDTIPKSKFLAL 294
Query: 325 AREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLL 384
+ + + + Q + A +R + + A + A T+
Sbjct: 295 GSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTSAPA 354
Query: 385 AEKAQITEEEA-KLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEE 443
+ Q+ E A+K + + + +KA + +E E + EA + +
Sbjct: 355 ITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQAEPEPTEAWKKKRERLDG 414
Query: 444 SERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPD 494
+ ++ + +DL +++E ++ + E+ K + M +P P P +
Sbjct: 415 ENIYIRHSNLMLEDLDKSQEEIKKHHASISEL--KKNF--MESVPEPRPSE 461
>gi|207113199 erythrocyte membrane protein band 4.1-like 2 isoform b
[Homo sapiens]
Length = 673
Score = 128 bits (322), Expect = 1e-29
Identities = 89/298 (29%), Positives = 150/298 (50%), Gaps = 22/298 (7%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMKW--KGKDLFDLVCRTLGLRETWFFGLQYTIK-DTVA 73
K+ KT ++ +D E++C+++ KG+ LFD VC L L E +FGL + +
Sbjct: 213 KKTKTVQCKVTLLDGT-EYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKN 271
Query: 74 WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYC 133
WL K++ + P F F KFYP + + L ++IT++ LQ+++ I ++ C
Sbjct: 272 WLDPAKEIKRQ--LRNLPWLFTFNVKFYPPDPSQ-LTEDITRYFLCLQLRQDIASGRLPC 328
Query: 134 PPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYA 193
LL SY +QA+ GDYDP H L++ + P + L EE++ +
Sbjct: 329 SFVTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKEL--------EEKVAELHK 380
Query: 194 EHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPK 253
HRG + +A+ ++L+ A+ L MYGV+ ++ +G ++ LGV A GL IY R+
Sbjct: 381 THRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRIN-- 438
Query: 254 ISFPWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLF 307
F W +I ISY F IK +++ F+ F R K + ++C+ +H +
Sbjct: 439 -RFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFY 495
>gi|207113195 erythrocyte membrane protein band 4.1-like 2 isoform b
[Homo sapiens]
Length = 673
Score = 128 bits (322), Expect = 1e-29
Identities = 89/298 (29%), Positives = 150/298 (50%), Gaps = 22/298 (7%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMKW--KGKDLFDLVCRTLGLRETWFFGLQYTIK-DTVA 73
K+ KT ++ +D E++C+++ KG+ LFD VC L L E +FGL + +
Sbjct: 213 KKTKTVQCKVTLLDGT-EYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKN 271
Query: 74 WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYC 133
WL K++ + P F F KFYP + + L ++IT++ LQ+++ I ++ C
Sbjct: 272 WLDPAKEIKRQ--LRNLPWLFTFNVKFYPPDPSQ-LTEDITRYFLCLQLRQDIASGRLPC 328
Query: 134 PPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYA 193
LL SY +QA+ GDYDP H L++ + P + L EE++ +
Sbjct: 329 SFVTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKEL--------EEKVAELHK 380
Query: 194 EHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPK 253
HRG + +A+ ++L+ A+ L MYGV+ ++ +G ++ LGV A GL IY R+
Sbjct: 381 THRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRIN-- 438
Query: 254 ISFPWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLF 307
F W +I ISY F IK +++ F+ F R K + ++C+ +H +
Sbjct: 439 -RFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFY 495
>gi|4503579 erythrocyte membrane protein band 4.1-like 2 isoform a
[Homo sapiens]
Length = 1005
Score = 128 bits (322), Expect = 1e-29
Identities = 89/298 (29%), Positives = 150/298 (50%), Gaps = 22/298 (7%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMKW--KGKDLFDLVCRTLGLRETWFFGLQYTIK-DTVA 73
K+ KT ++ +D E++C+++ KG+ LFD VC L L E +FGL + +
Sbjct: 213 KKTKTVQCKVTLLDGT-EYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKN 271
Query: 74 WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYC 133
WL K++ + P F F KFYP + + L ++IT++ LQ+++ I ++ C
Sbjct: 272 WLDPAKEIKRQ--LRNLPWLFTFNVKFYPPDPSQ-LTEDITRYFLCLQLRQDIASGRLPC 328
Query: 134 PPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYA 193
LL SY +QA+ GDYDP H L++ + P + L EE++ +
Sbjct: 329 SFVTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKEL--------EEKVAELHK 380
Query: 194 EHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPK 253
HRG + +A+ ++L+ A+ L MYGV+ ++ +G ++ LGV A GL IY R+
Sbjct: 381 THRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRIN-- 438
Query: 254 ISFPWNEIRNISYSDKEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLF 307
F W +I ISY F IK +++ F+ F R K + ++C+ +H +
Sbjct: 439 -RFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFY 495
>gi|42716291 erythrocyte membrane protein band 4.1 (elliptocytosis
1, RH-linked) isoform 2 [Homo sapiens]
Length = 641
Score = 126 bits (317), Expect = 5e-29
Identities = 101/410 (24%), Positives = 181/410 (44%), Gaps = 21/410 (5%)
Query: 30 DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTV-AWLKMDKKVLDHDVSK 88
D E E KG+DL VC L L E +FGL T WL K++ +
Sbjct: 10 DTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQ--VR 67
Query: 89 EEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQA 148
P F F KFYP + + L ++IT++ LQ+++ I+ ++ C LL SY +Q+
Sbjct: 68 GVPWNFTFNVKFYPPDPAQ-LTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 126
Query: 149 KYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYL 208
+ GDYDP +H +++ +L P + L EE++ + +R +A++E+L
Sbjct: 127 ELGDYDPELHGVDYVSDFKLAPNQTKEL--------EEKVMELHKSYRSMTPAQADLEFL 178
Query: 209 KIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSD 268
+ A+ L MYGV+ ++ +G +++LGV + GL +Y + R+ FPW ++ ISY
Sbjct: 179 ENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRIN---RFPWPKVLKISYKR 235
Query: 269 KEFTIKPLDKKIDVFK----FNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQ 324
F IK + + ++ F R K + ++C+ H F R D++ + A
Sbjct: 236 SSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCV-EHHTFFRLTSTDTIPKSKFLAL 294
Query: 325 AREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLL 384
+ + + + Q + A +R + + A + A T+
Sbjct: 295 GSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTSAPA 354
Query: 385 AEKAQITEEEA-KLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEA 433
+ Q+ E A+K + + + +KA + +E E + EA
Sbjct: 355 ITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQAEPEPTEA 404
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,632,446
Number of Sequences: 37866
Number of extensions: 952527
Number of successful extensions: 20938
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 546
Number of HSP's successfully gapped in prelim test: 1059
Number of HSP's that attempted gapping in prelim test: 7585
Number of HSP's gapped (non-prelim): 7167
length of query: 590
length of database: 18,247,518
effective HSP length: 108
effective length of query: 482
effective length of database: 14,157,990
effective search space: 6824151180
effective search space used: 6824151180
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.