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Search of human proteins with 32307124
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32307124 nuclear receptor coactivator 3 isoform b [Homo
sapiens]
(1420 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 2858 0.0
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 2852 0.0
gi|5729858 nuclear receptor coactivator 2 [Homo sapiens] 1012 0.0
gi|22538457 nuclear receptor coactivator 1 isoform 2 [Homo sapiens] 494 e-139
gi|22538459 nuclear receptor coactivator 1 isoform 3 [Homo sapiens] 494 e-139
gi|22538455 nuclear receptor coactivator 1 isoform 1 [Homo sapiens] 494 e-139
gi|71852582 aryl hydrocarbon receptor nuclear translocator-like ... 93 2e-18
gi|71852580 aryl hydrocarbon receptor nuclear translocator-like ... 93 2e-18
gi|42716311 aryl hydrocarbon receptor nuclear translocator-like ... 93 2e-18
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 86 3e-16
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 86 3e-16
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 85 6e-16
gi|33286444 mastermind-like 2 [Homo sapiens] 82 4e-15
gi|31745180 aryl hydrocarbon receptor nuclear translocator-like ... 81 6e-15
gi|110347429 mediator complex subunit 12 [Homo sapiens] 80 1e-14
gi|68303555 aryl hydrocarbon receptor nuclear translocator 2 [Ho... 80 1e-14
gi|56549696 E1A binding protein p400 [Homo sapiens] 79 2e-14
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 79 3e-14
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 79 3e-14
gi|4758010 clock [Homo sapiens] 79 4e-14
gi|93141033 PAX interacting protein 1 [Homo sapiens] 77 9e-14
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 77 2e-13
gi|30795242 aryl hydrocarbon receptor nuclear translocator isofo... 77 2e-13
gi|4502231 aryl hydrocarbon receptor nuclear translocator isofor... 77 2e-13
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 77 2e-13
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 76 2e-13
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 76 2e-13
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 76 2e-13
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 76 2e-13
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho... 76 2e-13
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 2858 bits (7409), Expect = 0.0
Identities = 1420/1420 (100%), Positives = 1420/1420 (100%)
Query: 1 MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDID 60
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDID
Sbjct: 1 MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDID 60
Query: 61 NFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQA 120
NFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQA
Sbjct: 61 NFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQA 120
Query: 121 LDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG 180
LDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
Sbjct: 121 LDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG 180
Query: 181 VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGE 240
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGE
Sbjct: 181 VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGE 240
Query: 241 DLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRC 300
DLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRC
Sbjct: 241 DLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRC 300
Query: 301 IQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR 360
IQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR
Sbjct: 301 IQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR 360
Query: 361 HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLA 420
HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLA
Sbjct: 361 HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLA 420
Query: 421 DPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNI 480
DPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNI
Sbjct: 421 DPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNI 480
Query: 481 MISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST 540
MISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST
Sbjct: 481 MISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST 540
Query: 541 LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKE 600
LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKE
Sbjct: 541 LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKE 600
Query: 601 SSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVS 660
SSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVS
Sbjct: 601 SSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVS 660
Query: 661 SSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN 720
SSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN
Sbjct: 661 SSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN 720
Query: 721 VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQE 780
VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQE
Sbjct: 721 VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQE 780
Query: 781 KDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLK 840
KDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLK
Sbjct: 781 KDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLK 840
Query: 841 SSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS 900
SSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS
Sbjct: 841 SSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS 900
Query: 901 SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPT 960
SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPT
Sbjct: 901 SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPT 960
Query: 961 LPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQV 1020
LPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQV
Sbjct: 961 LPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQV 1020
Query: 1021 SHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE 1080
SHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE
Sbjct: 1021 SHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE 1080
Query: 1081 LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMN 1140
LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMN
Sbjct: 1081 LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMN 1140
Query: 1141 QMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTA 1200
QMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTA
Sbjct: 1141 QMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTA 1200
Query: 1201 GGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQ 1260
GGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQ
Sbjct: 1201 GGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQ 1260
Query: 1261 QQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPA 1320
QQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPA
Sbjct: 1261 QQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPA 1320
Query: 1321 FGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQFAHQ 1380
FGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQFAHQ
Sbjct: 1321 FGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQFAHQ 1380
Query: 1381 GNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC 1420
GNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC
Sbjct: 1381 GNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC 1420
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 2852 bits (7394), Expect = 0.0
Identities = 1420/1424 (99%), Positives = 1420/1424 (99%), Gaps = 4/1424 (0%)
Query: 1 MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDID 60
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDID
Sbjct: 1 MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDID 60
Query: 61 NFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQA 120
NFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQA
Sbjct: 61 NFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQA 120
Query: 121 LDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG 180
LDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
Sbjct: 121 LDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG 180
Query: 181 VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGE 240
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGE
Sbjct: 181 VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGE 240
Query: 241 DLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRC 300
DLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRC
Sbjct: 241 DLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRC 300
Query: 301 IQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR 360
IQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR
Sbjct: 301 IQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR 360
Query: 361 HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLA 420
HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLA
Sbjct: 361 HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLA 420
Query: 421 DPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNI 480
DPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNI
Sbjct: 421 DPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNI 480
Query: 481 MISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST 540
MISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST
Sbjct: 481 MISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST 540
Query: 541 LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKE 600
LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKE
Sbjct: 541 LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKE 600
Query: 601 SSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVS 660
SSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVS
Sbjct: 601 SSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVS 660
Query: 661 SSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN 720
SSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN
Sbjct: 661 SSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN 720
Query: 721 VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQE 780
VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQE
Sbjct: 721 VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQE 780
Query: 781 KDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLK 840
KDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLK
Sbjct: 781 KDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLK 840
Query: 841 SSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS 900
SSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS
Sbjct: 841 SSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS 900
Query: 901 SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPT 960
SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPT
Sbjct: 901 SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPT 960
Query: 961 LPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQV 1020
LPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQV
Sbjct: 961 LPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQV 1020
Query: 1021 SHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE 1080
SHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE
Sbjct: 1021 SHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE 1080
Query: 1081 LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMN 1140
LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMN
Sbjct: 1081 LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMN 1140
Query: 1141 QMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTA 1200
QMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTA
Sbjct: 1141 QMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTA 1200
Query: 1201 GGAAVMRPMMQP----QQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ 1256
GGAAVMRPMMQP QQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ
Sbjct: 1201 GGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ 1260
Query: 1257 QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQ 1316
QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQ
Sbjct: 1261 QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQ 1320
Query: 1317 PDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQ 1376
PDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQ
Sbjct: 1321 PDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQ 1380
Query: 1377 FAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC 1420
FAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC
Sbjct: 1381 FAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC 1424
>gi|5729858 nuclear receptor coactivator 2 [Homo sapiens]
Length = 1464
Score = 1012 bits (2617), Expect = 0.0
Identities = 643/1508 (42%), Positives = 884/1508 (58%), Gaps = 168/1508 (11%)
Query: 1 MSGLGENL-DPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDI 59
MSG+GEN DP +++RKRK D G + EKR REQE+KYIEELAELI AN +DI
Sbjct: 1 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI 60
Query: 60 DNFNVKPDKCAILKETVRQIRQIKEQGKTIS-NDDDVQKADVSSTGQGVIDKDSLGPLLL 118
DNFN KPDKCAILKETV+QIRQIKEQ K + N D+VQK+DVSSTGQGVIDKD+LGP++L
Sbjct: 61 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML 120
Query: 119 QALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNL-PKST 177
+ALDGF FVVN +GN+VFVSENVTQYL+Y QE+L+N SVY+ILH D +F+KNL PKS
Sbjct: 121 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI 180
Query: 178 VNGVSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMME 237
VNG SW+ E R+ SHTFNCRML+K D E+ + + E Q+YETMQCFA+SQP+++ E
Sbjct: 181 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE 240
Query: 238 EGEDLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDII 297
EGEDLQSC+ICVARR+ ER + ESF TR DL GK+ ++DT+++R++M+PG+ED++
Sbjct: 241 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV 300
Query: 298 RRCIQRFFSLNDGQSWS-QKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPV 356
RRCIQ+F + ++G+S S KRH+ E G A + +YRFSL+DGT+V AQTKSKL R+
Sbjct: 301 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT 360
Query: 357 TNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGG----MSMSPNQGLQMP 412
TN+ +S H L REQN NP+ GQ + P+ +S+ S +P Q + +
Sbjct: 361 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS 420
Query: 413 SSRAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPG 472
S+ + + P M R+GGS + ++ GMQ+ ++ Q +NY L M+SP SPG
Sbjct: 421 SNINFPINGPKEQMGMPMGRFGGSGGMNHVS---GMQA-TTPQGSNYALKMNSPSQSSPG 476
Query: 473 LAPNQQNIMISPRNR------GSPKIASHQFSPVAGVHSPMASSGNTGN-HSFSSSSLSA 525
+ P Q M+SPR+R GSP+I QFSP +HSP+ +TGN HS+++SSL+A
Sbjct: 477 MNPGQPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNA 536
Query: 526 LQAISEGVGTSLLSTLSSPGPK---LDNSP-NMNITQPSKVSNQDSKSPLGFYCDQNPVE 581
LQA+SEG G SL S+L+SP K L NSP NMN SK+ + DSK G Y + P E
Sbjct: 537 LQALSEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGE--PSE 594
Query: 582 SSMCQSNSRDHLSDKESKES-------SVEGAENQRGPLESKGHKKLLQLLTCSSDDRGH 634
+ Q+ S H +++ S E A+ Q +SKG KLLQLLT SD
Sbjct: 595 GTTGQAESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSD---- 650
Query: 635 SSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNS 694
+ SPL SS S + ++G + + + HG+ L+EKH+ILH+LLQ+ +S
Sbjct: 651 -QMEPSPLASSL----------SDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSS 699
Query: 695 PAEVAKITAEATGKD---TSSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDAL 751
P ++AK+TAEATGKD SS T+ G +KQE +SPKKKE NALLRYLLD+DD D
Sbjct: 700 PVDLAKLTAEATGKDLSQESSSTAPGSEVTIKQEPVSPKKKE-NALLRYLLDKDDTKDIG 758
Query: 752 SKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSSD 811
E+ P++E +D+K +++ + + EK+ ++ E ++ +LDNL+ IL DL +S
Sbjct: 759 LPEITPKLERLDSKTDPASNTKLIAMKTEKE-EMSFEPGDQPGSELDNLEEILDDLQNSQ 817
Query: 812 FYNNSISSN-GSHLGT--KQQVFQ---------------GTNSLGLKSSQS--------- 844
+ G+ G+ KQ + G L+ SQS
Sbjct: 818 LPQLFPDTRPGAPAGSVDKQAIINDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQ 877
Query: 845 VQSIRPPYNRA--VSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGSSM 902
+ + P N ++L SP G PP++N S + ++P QP + GN M+ +Q N G+S
Sbjct: 878 LGRLLPNQNLPLDITLQSPTGAGPFPPIRNSSPYSVIP-QPGMMGNQGMIGNQGNLGNSS 936
Query: 903 GGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSI---- 958
G N T SG+W P S A R+ + S ++ RP GG I
Sbjct: 937 TGMIGNSASRPTMPSGEWA-PQSSAVRVTCAATTS----------AMNRPVQGGMIRNPA 985
Query: 959 PTLPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYG-QAAASNQLGSWPDGMLSM 1017
++P+R +S PG R L Q Q++ + P E+ M MG Y Q A NQ WP+ +L +
Sbjct: 986 ASIPMRPSSQPGQRQTL--QSQVMNIGPSELEMNMGGPQYSQQQAPPNQTAPWPESILPI 1043
Query: 1018 EQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALG 1077
+Q S +QNR +S DDL+ P E SDE ALLDQL+ L N D GLEEIDRALG
Sbjct: 1044 DQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALLDQLYLALRNFD--GLEEIDRALG 1101
Query: 1078 IPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQG--------GFHLQ 1129
IPELV+Q QA++P+Q F Q++ +M++QKA ++ Q Y +Q QG FH
Sbjct: 1102 IPELVSQSQAVDPEQ--FSSQDSNIMLEQKAPVFPQQYASQAQMAQGSYSPMQDPNFHTM 1159
Query: 1130 GQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQ 1189
GQ PS+ ++ Q P G+ P + N P QLR+QLQ RLQ Q Q+RQ
Sbjct: 1160 GQRPSYATLRMQ-------PRPGLRPTGLVQ----NQPNQLRLQLQHRLQAQ----QNRQ 1204
Query: 1190 ALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQ 1249
L ++ N + +RP + P Q +NAQM+AQR RE+L+ H R
Sbjct: 1205 PLMNQISN-VSNVNLTLRPGV-PTQAPINAQMLAQRQREILNQHLR-------------- 1248
Query: 1250 QQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQP 1309
Q+Q QQQQ QQ+ + Q + P++ A M ++ P +PQA QQFP+ P
Sbjct: 1249 -----QRQMHQQQQVQQRTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPP 1303
Query: 1310 NYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQS-SEMKGWPSGNLAR 1368
NYG+ QQPDP F ++P + +MS RM +Q+PMMQ QA YQ+ S++ GW GN+
Sbjct: 1304 NYGISQQPDPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGG 1363
Query: 1369 NSSFSQQ---QFAHQGNPAVYS---------------MVHMNGSSGHMGQMNMNPMPMSG 1410
NS FSQQ F Q N ++YS M MN +G + ++ +P SG
Sbjct: 1364 NSMFSQQSPPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSG 1423
Query: 1411 M-PMGPDQ 1417
+ MGP+Q
Sbjct: 1424 LSSMGPEQ 1431
>gi|22538457 nuclear receptor coactivator 1 isoform 2 [Homo sapiens]
Length = 1399
Score = 494 bits (1273), Expect = e-139
Identities = 340/866 (39%), Positives = 504/866 (58%), Gaps = 104/866 (12%)
Query: 1 MSGLGENL-DPLASDSRKRK-LPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSD 58
MSGLG++ DP DS KRK PCDT L S EKRRREQE+KY+EELAEL+SAN+SD
Sbjct: 1 MSGLGDSSSDPANPDSHKRKGSPCDT----LASSTEKRRREQENKYLEELAELLSANISD 56
Query: 59 IDNFNVKPDKCAILKETVRQIRQIK--EQGKTISNDDDVQKADVSSTGQGVIDKDSLGPL 116
ID+ +VKPDKC ILK+TV QI+ +K EQ K+ + DDDVQK+D+SS+ QGVI+K+SLGPL
Sbjct: 57 IDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS-TTDDDVQKSDISSSSQGVIEKESLGPL 115
Query: 117 LLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKN-LPK 175
LL+ALDGF FVVN +G IVFVSENVT YL Y QE+L+NTSVY+ILH D +F+KN LPK
Sbjct: 116 LLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPK 175
Query: 176 STVNGVSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAM 235
S VNGV W E R+ SHTFNCRML+ P E + E QRYE MQCF +SQP+++
Sbjct: 176 SLVNGVPWPQEATRRNSHTFNCRMLIHPPD---EPGTENQEACQRYEVMQCFTVSQPKSI 232
Query: 236 MEEGEDLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFED 295
E+GED QSC+IC+ARR+ + ESF+T+ D +GK+++IDT+SLR++ R G+ED
Sbjct: 233 QEDGEDFQSCLICIARRLPRPPAI--TGVESFMTKQDTTGKIISIDTSSLRAAGRTGWED 290
Query: 296 IIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNP 355
++R+CI FF + ++ +QE G A +P YRF L DGT+++A TK KL P
Sbjct: 291 LVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLC-YP 349
Query: 356 VTNDRHGFV-STHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGL----Q 410
+ D F+ H + RE +G P + G+ P N SV S+SP G+
Sbjct: 350 QSPDMQPFIMGIHIIDREHSGLSPQ-DDTNSGMSIPRV--NPSV-NPSISPAHGVARSST 405
Query: 411 MPSSRAYGLADPSTTGQMSGARYGGSSNIAS------LTPGPGM-------QSPSSYQNN 457
+P S + ++ Q S SN ++ +PG + Q +S Q++
Sbjct: 406 LPPSNSNMVSTRINRQQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSS 465
Query: 458 NYGLNMSSPPHGSPGLAPNQQNIMISPRNRGS------PKIASHQFSP-VAGVHSPM--- 507
N LN+++ P G++ Q +SPR + + P++ ++ F P ++ + SP+
Sbjct: 466 NPSLNLNNSPMEGTGISLAQ---FMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMT 522
Query: 508 ASSGNTGNHSFSSSSLSALQAISEGVGTSLLSTLSSP---GPKLDNSPNMNITQPSKVSN 564
+S+ N N S+S+ +++LQ ++EG S+ + SSP NSP+ QP+K +
Sbjct: 523 SSACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAES 582
Query: 565 QDSKSPLGFY----------CDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLE 614
+D+K D P++S + +N D LSD +SK S
Sbjct: 583 KDNKEIASILNEMIQSDNSSSDGKPLDSGLLHNN--DRLSDGDSKYSQTS---------- 630
Query: 615 SKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMH 674
KL+QLLT +++ + L ++ +D+SCK+ + + S+++SGG +S+
Sbjct: 631 ----HKLVQLLTTTAEQQ----LRHADIDTSCKDVLSCTGTSNSASANSSGGSCPSSH-- 680
Query: 675 GSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGNV-----VKQEQLSP 729
S L E+H+ILH+LLQ G SP+++ ++ E KD++S + G V +K E +
Sbjct: 681 -SSLTERHKILHRLLQEG-SPSDITTLSVEPDKKDSASTSVSVTGQVQGNSSIKLELDAS 738
Query: 730 KKKE--NNALLRYLLDRDD------PSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEK 781
KKKE ++ LLRYLLD+D+ P+ +L +++ +VE + +M C ++ P +
Sbjct: 739 KKKESKDHQLLRYLLDKDEKDLRSTPNLSLD-DVKVKVEKKE-QMDPCNTNPTPMTKPTP 796
Query: 782 DPKIKTETSEEGSGDLDNLDAILGDL 807
+ +IK E + + DLD D +L L
Sbjct: 797 E-EIKLEAQSQFTADLDQFDQLLPTL 821
Score = 198 bits (504), Expect = 3e-50
Identities = 274/1101 (24%), Positives = 440/1101 (39%), Gaps = 256/1101 (23%)
Query: 440 ASLTPGPGMQSPSSYQNNNYGLNMS-SPPHG---SPGLAPNQQNIMISPRNRGSPKIASH 495
+ L+P S S N +N S SP HG S L P+ N++ + NR
Sbjct: 369 SGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINRQQS----- 423
Query: 496 QFSPVAGVHSPMASSGNTGNHSFS---SSSLSALQAISEGVGTSLLSTLSSPGPKLDNSP 552
+ +HS S+ + SF S + A A+++G +S S+P L+NSP
Sbjct: 424 -----SDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASS---QSSNPSLNLNNSP 475
Query: 553 NMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGP 612
+ + +S SP M ++ ++S S A
Sbjct: 476 ----MEGTGISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSA------ 525
Query: 613 LESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSN 672
C++++R +S+ + VTS G++ + V +++
Sbjct: 526 --------------CNNNNRSYSN--------------IPVTSLQGMNEGPNNSVGFSAS 557
Query: 673 MHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGNVVKQEQLSPKKK 732
+L++ + + NSP+ + A+A KD I S + + S K
Sbjct: 558 --SPVLRQ--------MSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDNSSSDGKP 607
Query: 733 ENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEE 792
++ LL + D SD D+K SQ + + ++ T T+E+
Sbjct: 608 LDSGLLH---NNDRLSDG------------DSKYSQTSHKLV---------QLLTTTAEQ 643
Query: 793 GSGDLDNLDAILGDLTSSDFYNNSISSNGS---------HLGTKQQVFQGTNSLGLKSSQ 843
D +D D+ S +NS S+N S L + ++ G S
Sbjct: 644 QLRHAD-IDTSCKDVLSCTGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDI 702
Query: 844 SVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGSSMG 903
+ S+ P + S SV + V+ S+ K + + + +
Sbjct: 703 TTLSVEPDKKDSAS----TSVSVTGQVQGNSSI----KLELDASKKKESKDHQLLRYLLD 754
Query: 904 GPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNS--MGRPGGD----------------Y 945
+++ T S D + K +M+P N+N M +P + +
Sbjct: 755 KDEKDLRSTPNLSLDDVKVKVEKKEQMDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQF 814
Query: 946 NTSLPR-------------PALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIPMG 992
+ LP + G++ ++ ++S +P + + R E+ +
Sbjct: 815 DQLLPTLEKAAQLPGLCETDRMDGAVTSVTIKSEILPASLQSATARPTSRLNRLPELELE 874
Query: 993 MGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERA 1052
N +GQ +Q+ W + ++ ++ + + LD+L+ PP+ +EG++DE+A
Sbjct: 875 AIDNQFGQPGTGDQI-PWTNNTVTA--INQSKSEDQCISSQLDELLCPPTTVEGRNDEKA 931
Query: 1053 LLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAA--VMMDQKAGL 1110
LL+QL + LS D T L E+DRALGI +LV QG L+ + F Q+A ++M+++ L
Sbjct: 932 LLEQLVSFLSGKDETELAELDRALGIDKLV-QGGGLDVLSERFPPQQATPPLIMEERPNL 990
Query: 1111 YGQTYPAQGP------PMQGGFHLQGQSPSFNSMMNQMN-QQGNF-PLQGMHPRANIMRP 1162
Y Q Y + P P QG + Q PS +M Q+ +G F P GM PR + RP
Sbjct: 991 YSQPYSSPSPTANLPSPFQG---MVRQKPSLGTMPVQVTPPRGAFSPGMGMQPRQTLNRP 1047
Query: 1163 RTNTPKQLRMQLQQRLQG-QQFLNQSRQALELKMENPTAGGAAVMRPMMQPQ---QGFLN 1218
P QLR+QLQQRLQG QQ ++Q+RQA+ L TA MR MQ Q Q LN
Sbjct: 1048 PA-APNQLRLQLQQRLQGQQQLIHQNRQAI-LNQFAATAPVGINMRSGMQQQITPQPPLN 1105
Query: 1219 AQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSP 1278
AQM+AQR REL S QQ +Q+Q QQQ+ +QQ+ +
Sbjct: 1106 AQMLAQRQRELYS---------------------QQHRQRQLIQQQRAMLMRQQSFGNNL 1144
Query: 1279 PPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPA----FGRVSSPPNAMMSS 1334
PP S + + P +PQ PQQFPY PNYG PA F ++++ P A +++
Sbjct: 1145 PP----SSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLAN 1200
Query: 1335 R---------------MGPSQNPMMQH--------------------------------- 1346
R G NP MQ
Sbjct: 1201 RNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPI 1260
Query: 1347 --PQA--------ASIYQSSEMKGWPSGNLARNSSFSQ--QQFAHQGNPAVYS--MVHMN 1392
PQ+ AS YQS +MK W G + N+ FSQ Q P VY+ + ++
Sbjct: 1261 PPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVS 1320
Query: 1393 GSSGHMGQMNMNPMPMSGMPM 1413
+ G+ NMNPM M+ M M
Sbjct: 1321 MAGGNTNVQNMNPM-MAQMQM 1340
>gi|22538459 nuclear receptor coactivator 1 isoform 3 [Homo sapiens]
Length = 1440
Score = 494 bits (1273), Expect = e-139
Identities = 340/866 (39%), Positives = 504/866 (58%), Gaps = 104/866 (12%)
Query: 1 MSGLGENL-DPLASDSRKRK-LPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSD 58
MSGLG++ DP DS KRK PCDT L S EKRRREQE+KY+EELAEL+SAN+SD
Sbjct: 1 MSGLGDSSSDPANPDSHKRKGSPCDT----LASSTEKRRREQENKYLEELAELLSANISD 56
Query: 59 IDNFNVKPDKCAILKETVRQIRQIK--EQGKTISNDDDVQKADVSSTGQGVIDKDSLGPL 116
ID+ +VKPDKC ILK+TV QI+ +K EQ K+ + DDDVQK+D+SS+ QGVI+K+SLGPL
Sbjct: 57 IDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS-TTDDDVQKSDISSSSQGVIEKESLGPL 115
Query: 117 LLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKN-LPK 175
LL+ALDGF FVVN +G IVFVSENVT YL Y QE+L+NTSVY+ILH D +F+KN LPK
Sbjct: 116 LLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPK 175
Query: 176 STVNGVSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAM 235
S VNGV W E R+ SHTFNCRML+ P E + E QRYE MQCF +SQP+++
Sbjct: 176 SLVNGVPWPQEATRRNSHTFNCRMLIHPPD---EPGTENQEACQRYEVMQCFTVSQPKSI 232
Query: 236 MEEGEDLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFED 295
E+GED QSC+IC+ARR+ + ESF+T+ D +GK+++IDT+SLR++ R G+ED
Sbjct: 233 QEDGEDFQSCLICIARRLPRPPAI--TGVESFMTKQDTTGKIISIDTSSLRAAGRTGWED 290
Query: 296 IIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNP 355
++R+CI FF + ++ +QE G A +P YRF L DGT+++A TK KL P
Sbjct: 291 LVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLC-YP 349
Query: 356 VTNDRHGFV-STHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGL----Q 410
+ D F+ H + RE +G P + G+ P N SV S+SP G+
Sbjct: 350 QSPDMQPFIMGIHIIDREHSGLSPQ-DDTNSGMSIPRV--NPSV-NPSISPAHGVARSST 405
Query: 411 MPSSRAYGLADPSTTGQMSGARYGGSSNIAS------LTPGPGM-------QSPSSYQNN 457
+P S + ++ Q S SN ++ +PG + Q +S Q++
Sbjct: 406 LPPSNSNMVSTRINRQQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSS 465
Query: 458 NYGLNMSSPPHGSPGLAPNQQNIMISPRNRGS------PKIASHQFSP-VAGVHSPM--- 507
N LN+++ P G++ Q +SPR + + P++ ++ F P ++ + SP+
Sbjct: 466 NPSLNLNNSPMEGTGISLAQ---FMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMT 522
Query: 508 ASSGNTGNHSFSSSSLSALQAISEGVGTSLLSTLSSP---GPKLDNSPNMNITQPSKVSN 564
+S+ N N S+S+ +++LQ ++EG S+ + SSP NSP+ QP+K +
Sbjct: 523 SSACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAES 582
Query: 565 QDSKSPLGFY----------CDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLE 614
+D+K D P++S + +N D LSD +SK S
Sbjct: 583 KDNKEIASILNEMIQSDNSSSDGKPLDSGLLHNN--DRLSDGDSKYSQTS---------- 630
Query: 615 SKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMH 674
KL+QLLT +++ + L ++ +D+SCK+ + + S+++SGG +S+
Sbjct: 631 ----HKLVQLLTTTAEQQ----LRHADIDTSCKDVLSCTGTSNSASANSSGGSCPSSH-- 680
Query: 675 GSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGNV-----VKQEQLSP 729
S L E+H+ILH+LLQ G SP+++ ++ E KD++S + G V +K E +
Sbjct: 681 -SSLTERHKILHRLLQEG-SPSDITTLSVEPDKKDSASTSVSVTGQVQGNSSIKLELDAS 738
Query: 730 KKKE--NNALLRYLLDRDD------PSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEK 781
KKKE ++ LLRYLLD+D+ P+ +L +++ +VE + +M C ++ P +
Sbjct: 739 KKKESKDHQLLRYLLDKDEKDLRSTPNLSLD-DVKVKVEKKE-QMDPCNTNPTPMTKPTP 796
Query: 782 DPKIKTETSEEGSGDLDNLDAILGDL 807
+ +IK E + + DLD D +L L
Sbjct: 797 E-EIKLEAQSQFTADLDQFDQLLPTL 821
Score = 198 bits (504), Expect = 3e-50
Identities = 274/1101 (24%), Positives = 440/1101 (39%), Gaps = 256/1101 (23%)
Query: 440 ASLTPGPGMQSPSSYQNNNYGLNMS-SPPHG---SPGLAPNQQNIMISPRNRGSPKIASH 495
+ L+P S S N +N S SP HG S L P+ N++ + NR
Sbjct: 369 SGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINRQQS----- 423
Query: 496 QFSPVAGVHSPMASSGNTGNHSFS---SSSLSALQAISEGVGTSLLSTLSSPGPKLDNSP 552
+ +HS S+ + SF S + A A+++G +S S+P L+NSP
Sbjct: 424 -----SDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASS---QSSNPSLNLNNSP 475
Query: 553 NMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGP 612
+ + +S SP M ++ ++S S A
Sbjct: 476 ----MEGTGISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSA------ 525
Query: 613 LESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSN 672
C++++R +S+ + VTS G++ + V +++
Sbjct: 526 --------------CNNNNRSYSN--------------IPVTSLQGMNEGPNNSVGFSAS 557
Query: 673 MHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGNVVKQEQLSPKKK 732
+L++ + + NSP+ + A+A KD I S + + S K
Sbjct: 558 --SPVLRQ--------MSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDNSSSDGKP 607
Query: 733 ENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEE 792
++ LL + D SD D+K SQ + + ++ T T+E+
Sbjct: 608 LDSGLLH---NNDRLSDG------------DSKYSQTSHKLV---------QLLTTTAEQ 643
Query: 793 GSGDLDNLDAILGDLTSSDFYNNSISSNGS---------HLGTKQQVFQGTNSLGLKSSQ 843
D +D D+ S +NS S+N S L + ++ G S
Sbjct: 644 QLRHAD-IDTSCKDVLSCTGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDI 702
Query: 844 SVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGSSMG 903
+ S+ P + S SV + V+ S+ K + + + +
Sbjct: 703 TTLSVEPDKKDSAS----TSVSVTGQVQGNSSI----KLELDASKKKESKDHQLLRYLLD 754
Query: 904 GPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNS--MGRPGGD----------------Y 945
+++ T S D + K +M+P N+N M +P + +
Sbjct: 755 KDEKDLRSTPNLSLDDVKVKVEKKEQMDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQF 814
Query: 946 NTSLPR-------------PALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIPMG 992
+ LP + G++ ++ ++S +P + + R E+ +
Sbjct: 815 DQLLPTLEKAAQLPGLCETDRMDGAVTSVTIKSEILPASLQSATARPTSRLNRLPELELE 874
Query: 993 MGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERA 1052
N +GQ +Q+ W + ++ ++ + + LD+L+ PP+ +EG++DE+A
Sbjct: 875 AIDNQFGQPGTGDQI-PWTNNTVTA--INQSKSEDQCISSQLDELLCPPTTVEGRNDEKA 931
Query: 1053 LLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAA--VMMDQKAGL 1110
LL+QL + LS D T L E+DRALGI +LV QG L+ + F Q+A ++M+++ L
Sbjct: 932 LLEQLVSFLSGKDETELAELDRALGIDKLV-QGGGLDVLSERFPPQQATPPLIMEERPNL 990
Query: 1111 YGQTYPAQGP------PMQGGFHLQGQSPSFNSMMNQMN-QQGNF-PLQGMHPRANIMRP 1162
Y Q Y + P P QG + Q PS +M Q+ +G F P GM PR + RP
Sbjct: 991 YSQPYSSPSPTANLPSPFQG---MVRQKPSLGTMPVQVTPPRGAFSPGMGMQPRQTLNRP 1047
Query: 1163 RTNTPKQLRMQLQQRLQG-QQFLNQSRQALELKMENPTAGGAAVMRPMMQPQ---QGFLN 1218
P QLR+QLQQRLQG QQ ++Q+RQA+ L TA MR MQ Q Q LN
Sbjct: 1048 PA-APNQLRLQLQQRLQGQQQLIHQNRQAI-LNQFAATAPVGINMRSGMQQQITPQPPLN 1105
Query: 1219 AQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSP 1278
AQM+AQR REL S QQ +Q+Q QQQ+ +QQ+ +
Sbjct: 1106 AQMLAQRQRELYS---------------------QQHRQRQLIQQQRAMLMRQQSFGNNL 1144
Query: 1279 PPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPA----FGRVSSPPNAMMSS 1334
PP S + + P +PQ PQQFPY PNYG PA F ++++ P A +++
Sbjct: 1145 PP----SSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLAN 1200
Query: 1335 R---------------MGPSQNPMMQH--------------------------------- 1346
R G NP MQ
Sbjct: 1201 RNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPI 1260
Query: 1347 --PQA--------ASIYQSSEMKGWPSGNLARNSSFSQ--QQFAHQGNPAVYS--MVHMN 1392
PQ+ AS YQS +MK W G + N+ FSQ Q P VY+ + ++
Sbjct: 1261 PPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVS 1320
Query: 1393 GSSGHMGQMNMNPMPMSGMPM 1413
+ G+ NMNPM M+ M M
Sbjct: 1321 MAGGNTNVQNMNPM-MAQMQM 1340
>gi|22538455 nuclear receptor coactivator 1 isoform 1 [Homo sapiens]
Length = 1441
Score = 494 bits (1273), Expect = e-139
Identities = 340/866 (39%), Positives = 504/866 (58%), Gaps = 104/866 (12%)
Query: 1 MSGLGENL-DPLASDSRKRK-LPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSD 58
MSGLG++ DP DS KRK PCDT L S EKRRREQE+KY+EELAEL+SAN+SD
Sbjct: 1 MSGLGDSSSDPANPDSHKRKGSPCDT----LASSTEKRRREQENKYLEELAELLSANISD 56
Query: 59 IDNFNVKPDKCAILKETVRQIRQIK--EQGKTISNDDDVQKADVSSTGQGVIDKDSLGPL 116
ID+ +VKPDKC ILK+TV QI+ +K EQ K+ + DDDVQK+D+SS+ QGVI+K+SLGPL
Sbjct: 57 IDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS-TTDDDVQKSDISSSSQGVIEKESLGPL 115
Query: 117 LLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKN-LPK 175
LL+ALDGF FVVN +G IVFVSENVT YL Y QE+L+NTSVY+ILH D +F+KN LPK
Sbjct: 116 LLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPK 175
Query: 176 STVNGVSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAM 235
S VNGV W E R+ SHTFNCRML+ P E + E QRYE MQCF +SQP+++
Sbjct: 176 SLVNGVPWPQEATRRNSHTFNCRMLIHPPD---EPGTENQEACQRYEVMQCFTVSQPKSI 232
Query: 236 MEEGEDLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFED 295
E+GED QSC+IC+ARR+ + ESF+T+ D +GK+++IDT+SLR++ R G+ED
Sbjct: 233 QEDGEDFQSCLICIARRLPRPPAI--TGVESFMTKQDTTGKIISIDTSSLRAAGRTGWED 290
Query: 296 IIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNP 355
++R+CI FF + ++ +QE G A +P YRF L DGT+++A TK KL P
Sbjct: 291 LVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLC-YP 349
Query: 356 VTNDRHGFV-STHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGL----Q 410
+ D F+ H + RE +G P + G+ P N SV S+SP G+
Sbjct: 350 QSPDMQPFIMGIHIIDREHSGLSPQ-DDTNSGMSIPRV--NPSV-NPSISPAHGVARSST 405
Query: 411 MPSSRAYGLADPSTTGQMSGARYGGSSNIAS------LTPGPGM-------QSPSSYQNN 457
+P S + ++ Q S SN ++ +PG + Q +S Q++
Sbjct: 406 LPPSNSNMVSTRINRQQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSS 465
Query: 458 NYGLNMSSPPHGSPGLAPNQQNIMISPRNRGS------PKIASHQFSP-VAGVHSPM--- 507
N LN+++ P G++ Q +SPR + + P++ ++ F P ++ + SP+
Sbjct: 466 NPSLNLNNSPMEGTGISLAQ---FMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMT 522
Query: 508 ASSGNTGNHSFSSSSLSALQAISEGVGTSLLSTLSSP---GPKLDNSPNMNITQPSKVSN 564
+S+ N N S+S+ +++LQ ++EG S+ + SSP NSP+ QP+K +
Sbjct: 523 SSACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAES 582
Query: 565 QDSKSPLGFY----------CDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLE 614
+D+K D P++S + +N D LSD +SK S
Sbjct: 583 KDNKEIASILNEMIQSDNSSSDGKPLDSGLLHNN--DRLSDGDSKYSQTS---------- 630
Query: 615 SKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMH 674
KL+QLLT +++ + L ++ +D+SCK+ + + S+++SGG +S+
Sbjct: 631 ----HKLVQLLTTTAEQQ----LRHADIDTSCKDVLSCTGTSNSASANSSGGSCPSSH-- 680
Query: 675 GSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGNV-----VKQEQLSP 729
S L E+H+ILH+LLQ G SP+++ ++ E KD++S + G V +K E +
Sbjct: 681 -SSLTERHKILHRLLQEG-SPSDITTLSVEPDKKDSASTSVSVTGQVQGNSSIKLELDAS 738
Query: 730 KKKE--NNALLRYLLDRDD------PSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEK 781
KKKE ++ LLRYLLD+D+ P+ +L +++ +VE + +M C ++ P +
Sbjct: 739 KKKESKDHQLLRYLLDKDEKDLRSTPNLSLD-DVKVKVEKKE-QMDPCNTNPTPMTKPTP 796
Query: 782 DPKIKTETSEEGSGDLDNLDAILGDL 807
+ +IK E + + DLD D +L L
Sbjct: 797 E-EIKLEAQSQFTADLDQFDQLLPTL 821
Score = 198 bits (504), Expect = 3e-50
Identities = 274/1101 (24%), Positives = 440/1101 (39%), Gaps = 256/1101 (23%)
Query: 440 ASLTPGPGMQSPSSYQNNNYGLNMS-SPPHG---SPGLAPNQQNIMISPRNRGSPKIASH 495
+ L+P S S N +N S SP HG S L P+ N++ + NR
Sbjct: 369 SGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINRQQS----- 423
Query: 496 QFSPVAGVHSPMASSGNTGNHSFS---SSSLSALQAISEGVGTSLLSTLSSPGPKLDNSP 552
+ +HS S+ + SF S + A A+++G +S S+P L+NSP
Sbjct: 424 -----SDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASS---QSSNPSLNLNNSP 475
Query: 553 NMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGP 612
+ + +S SP M ++ ++S S A
Sbjct: 476 ----MEGTGISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSA------ 525
Query: 613 LESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSN 672
C++++R +S+ + VTS G++ + V +++
Sbjct: 526 --------------CNNNNRSYSN--------------IPVTSLQGMNEGPNNSVGFSAS 557
Query: 673 MHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGNVVKQEQLSPKKK 732
+L++ + + NSP+ + A+A KD I S + + S K
Sbjct: 558 --SPVLRQ--------MSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDNSSSDGKP 607
Query: 733 ENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEE 792
++ LL + D SD D+K SQ + + ++ T T+E+
Sbjct: 608 LDSGLLH---NNDRLSDG------------DSKYSQTSHKLV---------QLLTTTAEQ 643
Query: 793 GSGDLDNLDAILGDLTSSDFYNNSISSNGS---------HLGTKQQVFQGTNSLGLKSSQ 843
D +D D+ S +NS S+N S L + ++ G S
Sbjct: 644 QLRHAD-IDTSCKDVLSCTGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDI 702
Query: 844 SVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGSSMG 903
+ S+ P + S SV + V+ S+ K + + + +
Sbjct: 703 TTLSVEPDKKDSAS----TSVSVTGQVQGNSSI----KLELDASKKKESKDHQLLRYLLD 754
Query: 904 GPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNS--MGRPGGD----------------Y 945
+++ T S D + K +M+P N+N M +P + +
Sbjct: 755 KDEKDLRSTPNLSLDDVKVKVEKKEQMDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQF 814
Query: 946 NTSLPR-------------PALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIPMG 992
+ LP + G++ ++ ++S +P + + R E+ +
Sbjct: 815 DQLLPTLEKAAQLPGLCETDRMDGAVTSVTIKSEILPASLQSATARPTSRLNRLPELELE 874
Query: 993 MGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERA 1052
N +GQ +Q+ W + ++ ++ + + LD+L+ PP+ +EG++DE+A
Sbjct: 875 AIDNQFGQPGTGDQI-PWTNNTVTA--INQSKSEDQCISSQLDELLCPPTTVEGRNDEKA 931
Query: 1053 LLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAA--VMMDQKAGL 1110
LL+QL + LS D T L E+DRALGI +LV QG L+ + F Q+A ++M+++ L
Sbjct: 932 LLEQLVSFLSGKDETELAELDRALGIDKLV-QGGGLDVLSERFPPQQATPPLIMEERPNL 990
Query: 1111 YGQTYPAQGP------PMQGGFHLQGQSPSFNSMMNQMN-QQGNF-PLQGMHPRANIMRP 1162
Y Q Y + P P QG + Q PS +M Q+ +G F P GM PR + RP
Sbjct: 991 YSQPYSSPSPTANLPSPFQG---MVRQKPSLGTMPVQVTPPRGAFSPGMGMQPRQTLNRP 1047
Query: 1163 RTNTPKQLRMQLQQRLQG-QQFLNQSRQALELKMENPTAGGAAVMRPMMQPQ---QGFLN 1218
P QLR+QLQQRLQG QQ ++Q+RQA+ L TA MR MQ Q Q LN
Sbjct: 1048 PA-APNQLRLQLQQRLQGQQQLIHQNRQAI-LNQFAATAPVGINMRSGMQQQITPQPPLN 1105
Query: 1219 AQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSP 1278
AQM+AQR REL S QQ +Q+Q QQQ+ +QQ+ +
Sbjct: 1106 AQMLAQRQRELYS---------------------QQHRQRQLIQQQRAMLMRQQSFGNNL 1144
Query: 1279 PPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPA----FGRVSSPPNAMMSS 1334
PP S + + P +PQ PQQFPY PNYG PA F ++++ P A +++
Sbjct: 1145 PP----SSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLAN 1200
Query: 1335 R---------------MGPSQNPMMQH--------------------------------- 1346
R G NP MQ
Sbjct: 1201 RNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPI 1260
Query: 1347 --PQA--------ASIYQSSEMKGWPSGNLARNSSFSQ--QQFAHQGNPAVYS--MVHMN 1392
PQ+ AS YQS +MK W G + N+ FSQ Q P VY+ + ++
Sbjct: 1261 PPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVS 1320
Query: 1393 GSSGHMGQMNMNPMPMSGMPM 1413
+ G+ NMNPM M+ M M
Sbjct: 1321 MAGGNTNVQNMNPM-MAQMQM 1340
>gi|71852582 aryl hydrocarbon receptor nuclear translocator-like
isoform b [Homo sapiens]
Length = 582
Score = 93.2 bits (230), Expect = 2e-18
Identities = 133/536 (24%), Positives = 217/536 (40%), Gaps = 90/536 (16%)
Query: 34 EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDD 93
EKRRR++ + +I+ELA L+ + + K DK +L+ V+ ++ ++ G T +
Sbjct: 38 EKRRRDKMNSFIDELASLVPT----CNAMSRKLDKLTVLRMAVQHMKTLR--GAT----N 87
Query: 94 DVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRD-GNIVFVSENVTQYLQYKQEDL 152
+A+ T + D L L+L+A DGFLFVV D G I+FVSE+V + L Y Q DL
Sbjct: 88 PYTEANYKPT---FLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDL 144
Query: 153 VNTSVYNILHEEDRKDFLKNLPKSTV----------NGVSWTNETQRQKS-------HTF 195
+ S+++ LH +D + L S G+ + S +F
Sbjct: 145 IGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSF 204
Query: 196 NCRMLMKTPHDILEDIN-----ASPEMRQRYETMQC--FALSQPRAMMEEGEDLQ----- 243
CRM P +ED + + + R+ + T+ + S P M ED +
Sbjct: 205 FCRMKCNRPSVKVEDKDFPSTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEG 264
Query: 244 ---SCMICVARRITTGERTFPSNPE------SFITRHDLSGKVVNIDTNSLRSSMRPGFE 294
SC++ + R+ + P N E +++RH + GK V +D + E
Sbjct: 265 CNLSCLVAIG-RLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQE 323
Query: 295 DIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRN 354
+ C + F D + H Q T Y+F + DG+ +T +++ F N
Sbjct: 324 LLGTSCYEYFH--QDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMN 381
Query: 355 PVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSS 414
P T + VST+ + N G P + S+ M S G +
Sbjct: 382 PWTKEVEYIVSTNTV------VLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKR--- 432
Query: 415 RAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQ-------SPSSYQNNNYGLNMSSPP 467
P+ G G R G+ I + M+ SPSS ++ + + PP
Sbjct: 433 -----THPTVPGIPGGTR-AGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPP 486
Query: 468 HGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSL 523
S +P + I+ N G+P I P +G+ S A +S SSS L
Sbjct: 487 DAS---SPGGKKIL----NGGTPDI------PSSGLLSGQAQENPGYPYSDSSSIL 529
>gi|71852580 aryl hydrocarbon receptor nuclear translocator-like
isoform a [Homo sapiens]
Length = 625
Score = 93.2 bits (230), Expect = 2e-18
Identities = 133/536 (24%), Positives = 217/536 (40%), Gaps = 90/536 (16%)
Query: 34 EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDD 93
EKRRR++ + +I+ELA L+ + + K DK +L+ V+ ++ ++ G T +
Sbjct: 81 EKRRRDKMNSFIDELASLVPT----CNAMSRKLDKLTVLRMAVQHMKTLR--GAT----N 130
Query: 94 DVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRD-GNIVFVSENVTQYLQYKQEDL 152
+A+ T + D L L+L+A DGFLFVV D G I+FVSE+V + L Y Q DL
Sbjct: 131 PYTEANYKPT---FLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDL 187
Query: 153 VNTSVYNILHEEDRKDFLKNLPKSTV----------NGVSWTNETQRQKS-------HTF 195
+ S+++ LH +D + L S G+ + S +F
Sbjct: 188 IGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSF 247
Query: 196 NCRMLMKTPHDILEDIN-----ASPEMRQRYETMQC--FALSQPRAMMEEGEDLQ----- 243
CRM P +ED + + + R+ + T+ + S P M ED +
Sbjct: 248 FCRMKCNRPSVKVEDKDFPSTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEG 307
Query: 244 ---SCMICVARRITTGERTFPSNPE------SFITRHDLSGKVVNIDTNSLRSSMRPGFE 294
SC++ + R+ + P N E +++RH + GK V +D + E
Sbjct: 308 CNLSCLVAIG-RLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQE 366
Query: 295 DIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRN 354
+ C + F D + H Q T Y+F + DG+ +T +++ F N
Sbjct: 367 LLGTSCYEYFH--QDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMN 424
Query: 355 PVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSS 414
P T + VST+ + N G P + S+ M S G +
Sbjct: 425 PWTKEVEYIVSTNTV------VLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKR--- 475
Query: 415 RAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQ-------SPSSYQNNNYGLNMSSPP 467
P+ G G R G+ I + M+ SPSS ++ + + PP
Sbjct: 476 -----THPTVPGIPGGTR-AGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPP 529
Query: 468 HGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSL 523
S +P + I+ N G+P I P +G+ S A +S SSS L
Sbjct: 530 DAS---SPGGKKIL----NGGTPDI------PSSGLLSGQAQENPGYPYSDSSSIL 572
>gi|42716311 aryl hydrocarbon receptor nuclear translocator-like
isoform a [Homo sapiens]
Length = 625
Score = 93.2 bits (230), Expect = 2e-18
Identities = 133/536 (24%), Positives = 217/536 (40%), Gaps = 90/536 (16%)
Query: 34 EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDD 93
EKRRR++ + +I+ELA L+ + + K DK +L+ V+ ++ ++ G T +
Sbjct: 81 EKRRRDKMNSFIDELASLVPT----CNAMSRKLDKLTVLRMAVQHMKTLR--GAT----N 130
Query: 94 DVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRD-GNIVFVSENVTQYLQYKQEDL 152
+A+ T + D L L+L+A DGFLFVV D G I+FVSE+V + L Y Q DL
Sbjct: 131 PYTEANYKPT---FLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDL 187
Query: 153 VNTSVYNILHEEDRKDFLKNLPKSTV----------NGVSWTNETQRQKS-------HTF 195
+ S+++ LH +D + L S G+ + S +F
Sbjct: 188 IGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSF 247
Query: 196 NCRMLMKTPHDILEDIN-----ASPEMRQRYETMQC--FALSQPRAMMEEGEDLQ----- 243
CRM P +ED + + + R+ + T+ + S P M ED +
Sbjct: 248 FCRMKCNRPSVKVEDKDFPSTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEG 307
Query: 244 ---SCMICVARRITTGERTFPSNPE------SFITRHDLSGKVVNIDTNSLRSSMRPGFE 294
SC++ + R+ + P N E +++RH + GK V +D + E
Sbjct: 308 CNLSCLVAIG-RLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQE 366
Query: 295 DIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRN 354
+ C + F D + H Q T Y+F + DG+ +T +++ F N
Sbjct: 367 LLGTSCYEYFH--QDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMN 424
Query: 355 PVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSS 414
P T + VST+ + N G P + S+ M S G +
Sbjct: 425 PWTKEVEYIVSTNTV------VLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKR--- 475
Query: 415 RAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQ-------SPSSYQNNNYGLNMSSPP 467
P+ G G R G+ I + M+ SPSS ++ + + PP
Sbjct: 476 -----THPTVPGIPGGTR-AGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPP 529
Query: 468 HGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSL 523
S +P + I+ N G+P I P +G+ S A +S SSS L
Sbjct: 530 DAS---SPGGKKIL----NGGTPDI------PSSGLLSGQAQENPGYPYSDSSSIL 572
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 85.9 bits (211), Expect = 3e-16
Identities = 99/352 (28%), Positives = 135/352 (38%), Gaps = 59/352 (16%)
Query: 1108 AGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFP--LQGMHPRANIMRPRTN 1165
AG G P +GP G L G S +M M+ G P GM P + +
Sbjct: 94 AGAAGIGMPPRGP----GQSLGGMG-SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTAT 148
Query: 1166 TPKQLRMQ---LQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMV 1222
QL++Q LQQ+ Q QQF Q + AL+ + + + MQ Q Q V
Sbjct: 149 PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ-----FQAV 203
Query: 1223 AQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ----------QQQQQQQQQQQQQQQQ 1272
Q+ ++L +QQ + + Q QQQ QQQQQQ QQQQQQQQQQQQQQQ
Sbjct: 204 VQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQA 263
Query: 1273 TQAFSP----------PPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQ------- 1315
QA P PP A P + Q PPQ P QP Q
Sbjct: 264 LQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ--PQQPPVAQNQPSQLPPQ 321
Query: 1316 -QPDPAFGRVSSPPNAM-------------MSSRMGPSQNPMMQHPQAASIYQSSEMKGW 1361
Q P + + P M M + P Q + Q A Q+++M
Sbjct: 322 SQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVA- 380
Query: 1362 PSGNLARNSSFSQQQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPM 1413
P + + P ++ + SS +G+ M + S +PM
Sbjct: 381 PGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPM 432
Score = 54.3 bits (129), Expect = 8e-07
Identities = 88/375 (23%), Positives = 135/375 (36%), Gaps = 74/375 (19%)
Query: 1038 VGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQG 1097
+G P +L GQ H++ + AT ++ +L + +Q FQ
Sbjct: 119 MGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQL-------QLQQVALQQQQQQQQFQQ 171
Query: 1098 QEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRA 1157
Q+ A + Q+ Q + AQ MQ F Q + Q QQ + +
Sbjct: 172 QQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQ--QLQQQQQQQQHLIKLHHQNQQ 229
Query: 1158 NIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQ-ALELK-------MENPTAGGAAVM--- 1206
I + + + ++QLQQ+ Q QQ Q +Q AL+ + M+ P + +
Sbjct: 230 QIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQ 289
Query: 1207 ----------RPMMQPQQGFLNAQMVAQ-----RSRELLSHH-------------FRQQR 1238
+P QPQQ + +Q +++ L+S + R
Sbjct: 290 LQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR 349
Query: 1239 VAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQ---QQQTQA-----------FSPPPNVTA 1284
M++QQ Q Q QQQQ Q Q Q Q T+A F P V+A
Sbjct: 350 APMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSA 409
Query: 1285 SPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQ------------PDPAFGRVSSPPNAMM 1332
PS L M Q P + GQQ P P G+ SS PN+ +
Sbjct: 410 IPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNV 469
Query: 1333 SSRMGPSQNPMMQHP 1347
SS PS + + P
Sbjct: 470 SSGPAPSPSSFLPSP 484
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 85.5 bits (210), Expect = 3e-16
Identities = 87/260 (33%), Positives = 112/260 (43%), Gaps = 38/260 (14%)
Query: 1108 AGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFP--LQGMHPRANIMRPRTN 1165
AG G P +GP G L G S +M M+ G P GM P + +
Sbjct: 94 AGAAGIGMPPRGP----GQSLGGMG-SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTAT 148
Query: 1166 TPKQLRMQ---LQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMV 1222
QL++Q LQQ+ Q QQF Q + AL+ + + + MQ Q Q V
Sbjct: 149 PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ-----FQAV 203
Query: 1223 AQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ----------QQQQQQQQQQQQQQQQ 1272
Q+ ++L +QQ + + Q QQQ QQQQQQ QQQQQQQQQQQQQQQ
Sbjct: 204 VQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQA 263
Query: 1273 TQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMM 1332
QA P P M P QA PQQ Q ++ QP P + PP A
Sbjct: 264 LQAQPP----IQQPPMQ--QPQPPPSQALPQQL-QQMHHTQHHQPPP---QPQQPPVAQN 313
Query: 1333 SSRMGPSQN---PMMQHPQA 1349
P Q+ P++ QA
Sbjct: 314 QPSQLPPQSQTQPLVSQAQA 333
Score = 59.7 bits (143), Expect = 2e-08
Identities = 85/345 (24%), Positives = 128/345 (37%), Gaps = 54/345 (15%)
Query: 1038 VGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQG 1097
+G P +L GQ H++ + AT ++ +L + +Q FQ
Sbjct: 119 MGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQL-------QLQQVALQQQQQQQQFQQ 171
Query: 1098 QEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRA 1157
Q+ A + Q+ Q + AQ MQ F Q + Q QQ + +
Sbjct: 172 QQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQ--QLQQQQQQQQHLIKLHHQNQQ 229
Query: 1158 NIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQ-ALELK-------MENPTAGGAAVM--- 1206
I + + + ++QLQQ+ Q QQ Q +Q AL+ + M+ P + +
Sbjct: 230 QIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQ 289
Query: 1207 ----------RPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQ------- 1249
+P QPQQ + +Q + + Q A+ Q Q
Sbjct: 290 LQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR 349
Query: 1250 -----QQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQ--APP 1302
QQ Q Q QQQQ Q Q Q A P V S S +L+ P+ Q P
Sbjct: 350 APMVVQQPPVQPQVQQQQTAVQTAQAAQMVA----PGVQVSQSSLPMLSSPSPGQQVQTP 405
Query: 1303 QQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHP 1347
Q P P QP P G+ SS PN+ +SS PS + + P
Sbjct: 406 QSMPPPP------QPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSP 444
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 84.7 bits (208), Expect = 6e-16
Identities = 121/418 (28%), Positives = 161/418 (38%), Gaps = 77/418 (18%)
Query: 921 GLPNSKAG--RMEPMNSNSMGRPGGDY-NTSLPRPALGGSIPTLPLRSNSIPGARPVLQQ 977
G P +AG R+ P G+PGG + NT+L QQ
Sbjct: 3646 GPPGGQAGGLRLTPGGMALPGQPGGPFLNTALA-------------------------QQ 3680
Query: 978 QQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDL 1037
QQQ G + G G A + LG PD L E+ Q R L L
Sbjct: 3681 QQQQHSGGAGSLAGPSGGFFPGNLALRS-LG--PDSRLLQERQLQLQQQRMQLAQKLQQ- 3736
Query: 1038 VGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALG------IPELVNQG---QAL 1088
+ Q ++ LL Q+ G++ ++ALG +P +QG Q L
Sbjct: 3737 -----QQQQQQQQQHLLGQVAIQQQQQQGPGVQT-NQALGPKPQGLMPPSSHQGLLVQQL 3790
Query: 1089 EPK-----QDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMN 1143
P+ Q + AV+ Q G G QGP Q L QS +S Q+
Sbjct: 3791 SPQPPQGPQGMLGPAQVAVLQQQHPGALGP----QGPHRQV---LMTQSRVLSSP--QLA 3841
Query: 1144 QQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQF-LNQSRQALELKMENPTAGG 1202
QQG +M R T +Q + Q Q + QG L+ +Q+L P
Sbjct: 3842 QQGQ----------GLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSA 3891
Query: 1203 AAV-MRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQ 1261
+ +Q QQ Q + Q+ ++ L + Q+ + QQQQQQ QQQQQQQ QQQ
Sbjct: 3892 QPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQ 3951
Query: 1262 QQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDP 1319
QQQ QQQQQQQ Q F GLL +P QQ Q G G P
Sbjct: 3952 QQQLQQQQQQQQQQFQQ----QQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKP 4005
Score = 66.2 bits (160), Expect = 2e-10
Identities = 72/246 (29%), Positives = 96/246 (39%), Gaps = 31/246 (12%)
Query: 1180 GQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQR----SRELLSHHFR 1235
G FLN AL + + +GGA + P GF + + SR L +
Sbjct: 3669 GGPFLNT---ALAQQQQQQHSGGAG---SLAGPSGGFFPGNLALRSLGPDSRLLQERQLQ 3722
Query: 1236 QQRVAMMMQQQQQQQQQQQQQQQQQ--------QQQQQQQQQQQQTQAFSPPPNVTASPS 1287
Q+ MQ Q+ QQQQQQQQQQQ QQQQQQ Q QA P P PS
Sbjct: 3723 LQQ--QRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPS 3780
Query: 1288 M-DGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQH 1346
GLL QQ QP G PA V + GP + +M
Sbjct: 3781 SHQGLLV---------QQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQ 3831
Query: 1347 PQAASIYQSSEMKGWPSGNLARNSSFSQQQFAHQGNPAVYSMVHMNGS-SGHMGQMNMNP 1405
+ S Q ++ G+ + QQQ HQ ++ + H+ S H GQ ++
Sbjct: 3832 SRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSA 3891
Query: 1406 MPMSGM 1411
PM +
Sbjct: 3892 QPMGSL 3897
Score = 50.4 bits (119), Expect = 1e-05
Identities = 44/155 (28%), Positives = 68/155 (43%), Gaps = 23/155 (14%)
Query: 1242 MMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPP--------PNVTASPSMDGL-- 1291
+++ ++++ Q++QQ Q Q QQQQQQQQQ S P P+ +SPS+ G
Sbjct: 3252 LLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQ 3311
Query: 1292 -----LAGPTMPQAPPQQFPYQ-PNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQ 1345
LAG P P P Q P + + Q+ P+ VS+ + M+S + G + Q
Sbjct: 3312 QLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGH-MLSGQHGGQAGLVPQ 3370
Query: 1346 HPQAASIYQSSEMKGWPSGNLARNSSFSQQQFAHQ 1380
+ Q P G + + QQ A Q
Sbjct: 3371 QSSQPVLSQK------PMGTMPPSMCMKPQQLAMQ 3399
Score = 49.3 bits (116), Expect = 3e-05
Identities = 55/207 (26%), Positives = 82/207 (39%), Gaps = 16/207 (7%)
Query: 1181 QQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVA 1240
Q L + LE M+N T P++Q QG ++ + R Q
Sbjct: 4150 QNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQ------LRAQLQG 4203
Query: 1241 MMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPP---PNVTASPSMDGLLAGPTM 1297
++ + Q + QQQQQ Q Q+Q QQ Q +PP P SP L P +
Sbjct: 4204 VLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQL 4263
Query: 1298 PQAP-PQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSS 1356
P PQ P Q G G +P R+ +PP A+ + GP P+ P +S +
Sbjct: 4264 GGFPGPQTGPLQ-ELGAGPRPQGP-PRLPAPPGALST---GPVLGPVHPTPPPSSPQEPK 4318
Query: 1357 EMKGWPSGNLARNSSFSQQQFAHQGNP 1383
PS + ++ + +Q H G P
Sbjct: 4319 RPSQLPSPS-SQLPTEAQLPPTHPGTP 4344
Score = 44.7 bits (104), Expect = 6e-04
Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 19/209 (9%)
Query: 1165 NTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQ 1224
+T + L+MQL+ + +SR+AL K G P+ ++V +
Sbjct: 3516 HTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREF------PEADAEKLKLVTE 3569
Query: 1225 RSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTA 1284
+ ++ Q+++ + +QQ++ + + +QQQQQQQQQQQQQ + + +
Sbjct: 3570 QQSKI------QKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQ 3623
Query: 1285 SPSMDGLLAGPTMP---QAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQN 1341
SP + L G +P PPQ P G+ P P +++ + +Q
Sbjct: 3624 SPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPG-GMALPGQPGGPFLNTAL--AQQ 3680
Query: 1342 PMMQHPQAASIYQSSEMKGWPSGNLARNS 1370
QH A + G+ GNLA S
Sbjct: 3681 QQQQHSGGAGSL-AGPSGGFFPGNLALRS 3708
Score = 37.7 bits (86), Expect = 0.079
Identities = 116/544 (21%), Positives = 174/544 (31%), Gaps = 118/544 (21%)
Query: 903 GGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLP 962
GGP N + Q G S AG GG + +L +LG L
Sbjct: 3669 GGPFLNTALAQQQQQQHSGGAGSLAGPS-----------GGFFPGNLALRSLGPDSRLLQ 3717
Query: 963 LRSNSIPGARPVL-------QQQQQMLQMRPGEIPMGMGANPYGQAAASNQ-LGSWPDGM 1014
R + R L QQQQQ Q G++ + G +NQ LG P G+
Sbjct: 3718 ERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQ-QQQQGPGVQTNQALGPKPQGL 3776
Query: 1015 LSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSD--ERALLDQLHTLLSNTDATGLEEI 1072
M SH + LL L PP +G + A+L Q H + +
Sbjct: 3777 --MPPSSH----QGLLVQQLSPQ--PPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVL 3828
Query: 1073 ---DRALGIPELVNQGQAL------------EPKQDAFQGQEAAVMMDQKAGLYGQTYPA 1117
R L P+L QGQ L + +Q QG A + Q++ + P
Sbjct: 3829 MTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPK 3888
Query: 1118 QGPPMQGGFH-------LQGQSPSFNSMMNQMNQQGNFP---LQGMHPRANIMRPRTNTP 1167
G LQ Q Q+ QQ LQ + + + +
Sbjct: 3889 LSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQL 3948
Query: 1168 KQLRMQLQQRLQGQQ-------------FLNQSRQAL---ELKMENPTAGGAAVMRPMMQ 1211
+Q + QLQQ+ Q QQ LNQSR L + + + G +P+
Sbjct: 3949 QQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQH 4008
Query: 1212 ---------------PQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQ---------- 1246
+Q ++ + ++ + +H + +
Sbjct: 4009 FSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPS 4068
Query: 1247 ----------QQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPT 1296
Q Q Q Q Q Q + QQQQQ TA G L +
Sbjct: 4069 LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLH-----TAGGGSHGQLGSGS 4123
Query: 1297 MPQAPPQQFPY---QPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIY 1353
+A P+ QP+ +G QP + P M+ M + P Q P+ +
Sbjct: 4124 SSEA--SSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGP--QPPKPGPVL 4179
Query: 1354 QSSE 1357
QS +
Sbjct: 4180 QSGQ 4183
Score = 36.2 bits (82), Expect = 0.23
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 9/87 (10%)
Query: 1277 SPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQ------PNYGMGQQPDPAFGRVSSPPNA 1330
SPP SP+++ L+ P P+A P P++ P + P P R+S PP
Sbjct: 521 SPPEESPPSPALETPLSPP--PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE 578
Query: 1331 MMSSRMGPSQNPMMQHPQAASIYQSSE 1357
S P ++PM P+A+ ++ E
Sbjct: 579 SPMSPP-PEESPMSPPPEASRLFPPFE 604
Score = 35.4 bits (80), Expect = 0.39
Identities = 30/114 (26%), Positives = 44/114 (38%), Gaps = 21/114 (18%)
Query: 376 YRPNPNPVGQGIRPPMAGCNSSVGG----------------MSMSPNQGLQMPSSRAYGL 419
Y P P+P G +PPM G +S G +P+ L+ L
Sbjct: 2196 YPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNL 2255
Query: 420 ADPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGL 473
A P + G GG ++ L+P P +S + + L SSP +G P L
Sbjct: 2256 AVPESPGV-----GGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNL 2304
Score = 31.2 bits (69), Expect = 7.4
Identities = 42/147 (28%), Positives = 53/147 (36%), Gaps = 37/147 (25%)
Query: 382 PVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQM--SGARYGGSSNI 439
PV Q PP G NS G P L P S Y +A TG SG+ G SS
Sbjct: 2550 PVPQPGLPPPHGINSHFG-----PGPTLGKPQSTNYTVA----TGNFHPSGSPLGPSSGS 2600
Query: 440 ASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSP 499
+YGL+ PP P AP+ GS SH S
Sbjct: 2601 TG---------------ESYGLSPLRPPSVLPPPAPD-----------GSLPYLSHGASQ 2634
Query: 500 VAGVHSPMASSGNTGNHSFSSSSLSAL 526
+G+ SP+ + G SS + + L
Sbjct: 2635 RSGITSPVEKREDPGTGMGSSLATAEL 2661
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 82.0 bits (201), Expect = 4e-15
Identities = 82/268 (30%), Positives = 108/268 (40%), Gaps = 50/268 (18%)
Query: 1096 QGQEAAVMMDQKA-----GLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPL 1150
QG V+M QK +PA P QG P F+ +Q NQQ L
Sbjct: 522 QGGHLDVLMQQKPQDLSRSFINNPHPAM-EPRQGN-----TKPLFHFNSDQANQQMPSVL 575
Query: 1151 QGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMM 1210
P N P L QQ+ Q QQ Q +Q + + + +
Sbjct: 576 -----------PSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQ-------QQQQQ 617
Query: 1211 QPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1270
Q QQ ++AQ Q+ + A QQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 618 QQQQSSISAQQQQQQQSSIS---------AQQQQQQQQQQQQQQQQQQQQQQQQQQQPSS 668
Query: 1271 QQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNA 1330
Q Q+ P + SP P + QQ QP GMG Q + ++
Sbjct: 669 QPAQSLPSQP-LLRSPL-------PLQQKLLLQQMQNQPIAGMGYQVSQ---QQRQDQHS 717
Query: 1331 MMSSRMGPSQNP-MMQHPQAASIYQSSE 1357
++ GPS +P +P S Y +S+
Sbjct: 718 VVGQNTGPSPSPNPCSNPNTGSGYMNSQ 745
Score = 81.6 bits (200), Expect = 5e-15
Identities = 80/256 (31%), Positives = 108/256 (42%), Gaps = 41/256 (16%)
Query: 1113 QTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRM 1172
QT+ Q PM G GQS M N M + G QG H L +
Sbjct: 488 QTFSPQSSPMPGVAGGSGQS---KVMANYMYKAGP-SAQGGH---------------LDV 528
Query: 1173 QLQQRLQ--GQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQM---VAQRSR 1227
+QQ+ Q + F+N A+E + N +P+ N QM + +++
Sbjct: 529 LMQQKPQDLSRSFINNPHPAMEPRQGNT--------KPLFHFNSDQANQQMPSVLPSQNK 580
Query: 1228 ELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPS 1287
L H+ +QQ+ QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ + S S
Sbjct: 581 PSLLHYTQQQQ-----QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSS 635
Query: 1288 MDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQ-- 1345
+ Q QQ Q QQ + S P ++ S + Q ++Q
Sbjct: 636 ISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQM 695
Query: 1346 --HPQAASIYQSSEMK 1359
P A YQ S+ +
Sbjct: 696 QNQPIAGMGYQVSQQQ 711
Score = 44.3 bits (103), Expect = 8e-04
Identities = 141/718 (19%), Positives = 254/718 (35%), Gaps = 96/718 (13%)
Query: 593 LSDKESKESSVEGAENQRGPLESKGHKKLLQLLTCS--SDDRGHSSLTNSPLDSSCKESS 650
++ ++ +S G + + +G K Q++ S + R + + NS LD
Sbjct: 150 INGEQQPPASTPGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVG 209
Query: 651 VSVTSPSG---VSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATG 707
++++ G +++ S +S T M + L++ + + GN + +
Sbjct: 210 ENLSAGQGGLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEP 269
Query: 708 KDTSSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMS 767
+T S + DG + QE + P RY DDP + L + P+++ + N+++
Sbjct: 270 GETLSCSKHMDGQMT-QENIFPN--------RY---GDDPGEQL---MDPELQELFNELT 314
Query: 768 QCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTK 827
S P S E + I ++ ++D LG + S+ L +
Sbjct: 315 NI--SVPPMSDLELENMINATIKQDDPFNID-----LGQQSQR-------STPRPSLPME 360
Query: 828 QQVFQGTNSLGLKSSQSVQ-SIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLG 886
+ V + S GL S +RPP + ++ +S P+ ++ P QP G
Sbjct: 361 KIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSV---PQSQAQPQTG 417
Query: 887 -GNPRMMDSQENYGSSMG----GPNRNVTVT-----QTPSSGDWG-LPNSKAGRMEPMNS 935
G R + S + + NR Q +W LP+S P
Sbjct: 418 SGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQ 477
Query: 936 NSMGRPGGDYNT----SLPRPALGGSIPTLPLRSNSIPGARPVLQ--QQQQMLQMRPGEI 989
+ P T S P P + G + +N + A P Q ++Q +P ++
Sbjct: 478 EKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDL 537
Query: 990 PMGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGP-PSNLEGQS 1048
NP+ +ME T +PL + D PS L Q+
Sbjct: 538 SRSFINNPHP----------------AMEPRQGNT--KPLFHFNSDQANQQMPSVLPSQN 579
Query: 1049 DERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKA 1108
+LL T ++ + + Q Q + +Q Q Q+ + + Q+
Sbjct: 580 KP--------SLLHYTQQQQQQQQQQQQ--QQQQQQQQQQQQQQQQQQQQQQSSISAQQQ 629
Query: 1109 GLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPK 1168
+ AQ Q Q Q Q Q + P Q + + + P K
Sbjct: 630 QQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQK 689
Query: 1169 QLRMQLQQRL---QGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQ--QGFLNAQMVA 1223
L Q+Q + G Q Q RQ + + G + P P G++N+Q
Sbjct: 690 LLLQQMQNQPIAGMGYQVSQQQRQD-QHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ--- 745
Query: 1224 QRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPN 1281
+ LL+ ++ + Q +Q+QQ QQQ ++ Q Q PPP+
Sbjct: 746 ---QSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPD 800
Score = 34.3 bits (77), Expect = 0.88
Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 23/93 (24%)
Query: 1248 QQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPY 1307
QQ +Q +QQ + QQ QQQ Q P N +A PS G GP
Sbjct: 434 QQLKQIAANRQQHARMQQHQQQHQ-------PTNWSALPSSAGPSPGP------------ 474
Query: 1308 QPNYGMGQQPDPAFGRVS-SPPNAMMSSRMGPS 1339
+G + P P+FG+ + SP ++ M G S
Sbjct: 475 ---FGQEKIPSPSFGQQTFSPQSSPMPGVAGGS 504
>gi|31745180 aryl hydrocarbon receptor nuclear translocator-like 2
[Homo sapiens]
Length = 636
Score = 81.3 bits (199), Expect = 6e-15
Identities = 89/375 (23%), Positives = 162/375 (43%), Gaps = 58/375 (15%)
Query: 34 EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDD 93
EKRRR++ + IEEL SA + + K DK +L+ V+ +R +K G T S
Sbjct: 116 EKRRRDKMNNLIEEL----SAMIPQCNPMARKLDKLTVLRMAVQHLRSLK--GLTNSYVG 169
Query: 94 DVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRD-GNIVFVSENVTQYLQYKQEDL 152
S+ + + L L+L+ +GFLFVV + G I+FVS++V++ L Y Q L
Sbjct: 170 -------SNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASL 222
Query: 153 VNTSVYNILHEEDRKDFLKNLPKSTVN----------GVSWTNETQRQKSHTF------- 195
S+++ LH +D + L ++ G+ + ++ +
Sbjct: 223 TGQSLFDFLHPKDVAKVKEQLSSFDISPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSF 282
Query: 196 -----NCRMLMKTPHDILEDINASPEMRQRYETMQC--FALSQPRAMMEEGEDLQS---- 244
+C++ +K H L N+ + +++ T+ C + S P ++ E+ S
Sbjct: 283 FCRIKSCKISVKEEHGCLP--NSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKKDN 340
Query: 245 ----CMICVARR----ITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGF--E 294
C++ + R + P FITR ++GK V +D R++ G+ +
Sbjct: 341 SNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQ---RATAILGYLPQ 397
Query: 295 DIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRN 354
+++ +F +D + + K H T Y+F DG+ VT +++ F N
Sbjct: 398 ELLGTSCYEYFHQDDHNNLTDK-HKAVLQSKEKILTDSYKFRAKDGSFVTLKSQWFSFTN 456
Query: 355 PVTNDRHGFVSTHFL 369
P T + VS + L
Sbjct: 457 PWTKELEYIVSVNTL 471
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 80.5 bits (197), Expect = 1e-14
Identities = 75/235 (31%), Positives = 99/235 (42%), Gaps = 50/235 (21%)
Query: 1096 QGQEAAVMMDQKAGLYGQTYPAQGPPMQ--GGFHLQGQSPSFNSMMNQMN---------- 1143
QGQ + Q G+ GQ+ Q P G QG +P + + Q +
Sbjct: 1907 QGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPP 1966
Query: 1144 QQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQG----------------QQFLNQS 1187
+ P Q HP N P P + LQQR G Q+F +Q+
Sbjct: 1967 SYSSQPYQSTHPSTN---PTLVDPTR---HLQQRPSGYVHQQAPTYGHGLTSTQRFSHQT 2020
Query: 1188 RQALEL--KMENPTAGGAAV----------MRPMMQPQQGFLNAQMVAQRSRELLSHHFR 1235
Q + M +A G + Q QQ Q Q+ ++ +H R
Sbjct: 2021 LQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR 2080
Query: 1236 QQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQTQAFSPPPNVTASP 1286
QQ+ +++QQQQQQQQQQQQQQQQQQQQQQQ QQQQQ QA P P + P
Sbjct: 2081 QQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
Score = 57.0 bits (136), Expect = 1e-07
Identities = 103/444 (23%), Positives = 157/444 (35%), Gaps = 76/444 (17%)
Query: 877 PMLPKQPMLGGNPRMMDSQENYGSSMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSN 936
P PK G P ++E S G R+ T+T G + G P +
Sbjct: 1764 PEPPKTDKPGAAPP--STEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLL 1821
Query: 937 SMGRPGGDYNTSLPRPALGGSIPTLPLRSNS--IPGARPVLQQQQQM--LQMRPGEIP-- 990
PG + + + ++G PL + + RPV Q++ PG +P
Sbjct: 1822 HHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTT 1881
Query: 991 ----MGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEG 1046
MG+ + Y + Q + P G +Q+ Q++ +L S + P S+
Sbjct: 1882 MTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQ---QSQGMLGQSSVHQMTPSSSYGL 1938
Query: 1047 QSDERALLDQLHT-LLSNTDATGLEEIDRALGIPELVNQG-QALEPKQDAFQGQEAAVMM 1104
Q+ + H L +T G + P +Q Q+ P + +
Sbjct: 1939 QTSQGYTPYVSHVGLQQHTGPAG------TMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQ 1992
Query: 1105 DQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRT 1164
+ +G Q P G + Q+ M++ M P+ +A + R
Sbjct: 1993 QRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMT-----PMSAQGVQAGV-RSTA 2046
Query: 1165 NTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQ 1224
P+Q + Q QQ+ Q QQ Q +Q Q QQ + Q Q
Sbjct: 2047 ILPEQQQQQQQQQQQQQQQQQQQQQ--------------------QQQQQYHIRQQQQQQ 2086
Query: 1225 RSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQ----------------------Q 1262
R+ +QQ+ QQQQQQQQQQ QQQQQQQ Q
Sbjct: 2087 ILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQ 2146
Query: 1263 QQQQ-----QQQQQQTQAFSPPPN 1281
QQQQ +Q QQQ P P+
Sbjct: 2147 QQQQTAALVRQLQQQLSNTQPQPS 2170
Score = 33.9 bits (76), Expect = 1.1
Identities = 42/166 (25%), Positives = 64/166 (38%), Gaps = 24/166 (14%)
Query: 1251 QQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPN 1310
+QQQ Q Q+ +QQ QQ Q S +T S S GL Q PY +
Sbjct: 1899 RQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSY-GL-------QTSQGYTPYVSH 1950
Query: 1311 YGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNS 1370
G+ Q PA V ++ PS NP + P + ++ PSG + + +
Sbjct: 1951 VGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDP-------TRHLQQRPSGYVHQQA 2003
Query: 1371 S------FSQQQFAH---QGNPAVYSMVHMNGSSGHMGQMNMNPMP 1407
S Q+F+H Q P + +M M+ G + +P
Sbjct: 2004 PTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILP 2049
>gi|68303555 aryl hydrocarbon receptor nuclear translocator 2 [Homo
sapiens]
Length = 717
Score = 80.1 bits (196), Expect = 1e-14
Identities = 87/380 (22%), Positives = 167/380 (43%), Gaps = 62/380 (16%)
Query: 34 EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDD 93
E+RRR + ++YI EL++++ KPDK IL+ V ++ ++ G
Sbjct: 72 ERRRRNKMTQYITELSDMVPT----CSALARKPDKLTILRMAVSHMKSMRGTGN------ 121
Query: 94 DVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRD-GNIVFVSENVTQYLQYKQEDL 152
K+ + + + L L+L+A DGFLFVV + G +++VS++VT L Q +
Sbjct: 122 ---KSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEW 178
Query: 153 VNTSVYNILHEEDRKDFLKNL--PKSTVNG-----VSWTNETQRQKS---------HTFN 196
+++Y +H +D + + L ++++ G + T + + Q+S +F
Sbjct: 179 FGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFI 238
Query: 197 CRMLM-KTPHDILEDINASPEMRQR--------------YETMQC---------FALSQP 232
CRM P D L +N MR+R Y + C ++ P
Sbjct: 239 CRMRCGNAPLDHL-PLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMTIP 297
Query: 233 RAMMEEGEDLQSCMICVAR-RITTGERTFPSN----PESFITRHDLSGKVVNIDTNSLRS 287
+ G+ + C++ + R ++T+ N P F++RH+ G + +D + S
Sbjct: 298 EEDADVGQGSKYCLVAIGRLQVTSSPVCMDMNGMSVPTEFLSRHNSDGIITFVDPRCI-S 356
Query: 288 SMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQT 347
+ +D++ + I F D QS ++ Q L G + +YRF + + +T
Sbjct: 357 VIGYQPQDLLGKDILEFCHPED-QSHLRESFQQVVKLKGQVLSVMYRFRTKNREWMLIRT 415
Query: 348 KSKLFRNPVTNDRHGFVSTH 367
S F+NP +++ + T+
Sbjct: 416 SSFTFQNPYSDEIEYIICTN 435
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 79.3 bits (194), Expect = 2e-14
Identities = 71/217 (32%), Positives = 96/217 (44%), Gaps = 29/217 (13%)
Query: 1146 GNFPLQGMH----PRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAG 1201
G+ P Q +H PRA + P T TP + M Q ++ + S A+ P
Sbjct: 2631 GSAPAQVVHTQPPPRA-VGSPATATPDLVSMATTQGVRAVTSVTAS--AVVTTNLTPVQT 2687
Query: 1202 GAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQ 1261
A + P + G V + + HF+ ++ QQQQQQQQQQQQQQQQQQ
Sbjct: 2688 PARSLVPQVSQATG------VQLPGKTITPAHFQ-----LLRQQQQQQQQQQQQQQQQQQ 2736
Query: 1262 QQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFP------YQPNYGMGQ 1315
QQQQQQQQQQQT S P + G P +A + P + M
Sbjct: 2737 QQQQQQQQQQQTTTTSQ----VQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPP 2792
Query: 1316 QPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASI 1352
QP P + S+PP ++ SQ P Q PQ ++
Sbjct: 2793 QPPPPQAQ-SAPPQPTAQVQVQTSQPPQQQSPQLTTV 2828
Score = 44.3 bits (103), Expect = 8e-04
Identities = 54/208 (25%), Positives = 84/208 (40%), Gaps = 23/208 (11%)
Query: 1131 QSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRM-----QLQQRLQGQQFLN 1185
Q+P+ S++ Q++Q L G +T TP ++ Q QQ+ Q QQ
Sbjct: 2686 QTPA-RSLVPQVSQATGVQLPG----------KTITPAHFQLLRQQQQQQQQQQQQQQQQ 2734
Query: 1186 QSRQALELKMENPTAGGAAVMRPMMQPQ-QGFLNAQMVAQRSRELLSHHFRQQRVAMMMQ 1244
Q +Q + + + T + V P +Q Q Q + V + + E L ++Q++ M Q
Sbjct: 2735 QQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIK-MQKQKLQMPPQ 2793
Query: 1245 ----QQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQA 1300
Q Q Q Q Q Q Q QQQ Q T +P P + + L + +
Sbjct: 2794 PPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRV 2853
Query: 1301 PPQQFPYQPNYGMGQQPDPAFGRVSSPP 1328
P Q Q Q P PA ++ PP
Sbjct: 2854 PTSQLQAQGQM-QTQAPQPAQVALAKPP 2880
Score = 32.7 bits (73), Expect = 2.5
Identities = 34/133 (25%), Positives = 53/133 (39%), Gaps = 7/133 (5%)
Query: 1238 RVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTM 1297
+VA + ++ ++++ QQ+ QQ Q Q Q PPP P + A +
Sbjct: 2476 QVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQP--PPPPQQPPPPLPQPQAAGSQ 2533
Query: 1298 PQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSE 1357
P A P QP QP P V +P A + G S ++ S+ +S
Sbjct: 2534 PPAGPPAVQPQPQPQPQTQPQP----VQAPAKAQPAITTGGSA-AVLAGTIKTSVTGTSM 2588
Query: 1358 MKGWPSGNLARNS 1370
G SGN+ N+
Sbjct: 2589 PTGAVSGNVIVNT 2601
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 79.0 bits (193), Expect = 3e-14
Identities = 90/296 (30%), Positives = 115/296 (38%), Gaps = 71/296 (23%)
Query: 1116 PAQGP-PMQGGFH-LQGQSPSFNSMMNQMNQQGN--FPLQGMHP---------------- 1155
P+ GP P G H + G SP S+ + M G+ FP +GMH
Sbjct: 29 PSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVED 88
Query: 1156 ------RANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPM 1209
+ MRP + + Q QG + S + +P +GG M
Sbjct: 89 IHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQM 148
Query: 1210 MQPQQGFL---NAQMVAQRSR------ELLSHHFRQQRVAMMM----------------- 1243
Q G L + Q ++Q +R + H R Q +A M
Sbjct: 149 PPSQPGALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQG 208
Query: 1244 --------QQQQQQQQQQQQQQQQQQQQQQQQQQ--QQQTQAFSPPPNVTAS-PSMDG-L 1291
QQQQQQQQQQQQQQQQQQQQQQ QQQ Q QTQ P V + PS G
Sbjct: 209 KRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPE 268
Query: 1292 LAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHP 1347
L+GP+ PQ P P G +P PA + PP A + P P P
Sbjct: 269 LSGPSTPQKLPVPAP-------GGRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSP 317
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 79.0 bits (193), Expect = 3e-14
Identities = 90/296 (30%), Positives = 115/296 (38%), Gaps = 71/296 (23%)
Query: 1116 PAQGP-PMQGGFH-LQGQSPSFNSMMNQMNQQGN--FPLQGMHP---------------- 1155
P+ GP P G H + G SP S+ + M G+ FP +GMH
Sbjct: 29 PSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVED 88
Query: 1156 ------RANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPM 1209
+ MRP + + Q QG + S + +P +GG M
Sbjct: 89 IHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQM 148
Query: 1210 MQPQQGFL---NAQMVAQRSR------ELLSHHFRQQRVAMMM----------------- 1243
Q G L + Q ++Q +R + H R Q +A M
Sbjct: 149 PPSQPGALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQG 208
Query: 1244 --------QQQQQQQQQQQQQQQQQQQQQQQQQQ--QQQTQAFSPPPNVTAS-PSMDG-L 1291
QQQQQQQQQQQQQQQQQQQQQQ QQQ Q QTQ P V + PS G
Sbjct: 209 KRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPE 268
Query: 1292 LAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHP 1347
L+GP+ PQ P P G +P PA + PP A + P P P
Sbjct: 269 LSGPSTPQKLPVPAP-------GGRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSP 317
>gi|4758010 clock [Homo sapiens]
Length = 846
Score = 78.6 bits (192), Expect = 4e-14
Identities = 53/171 (30%), Positives = 88/171 (51%), Gaps = 13/171 (7%)
Query: 34 EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDD 93
EK+RR+Q + I+EL ++ N K DK +L++++ +R+ KE T +D
Sbjct: 43 EKKRRDQFNVLIKELGSMLPGNAR-------KMDKSTVLQKSIDFLRKHKEI--TAQSDA 93
Query: 94 DVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLV 153
+ D T + + L+L+ALDGF + DG+I++VSE+VT L++ DLV
Sbjct: 94 SEIRQDWKPT---FLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLPSDLV 150
Query: 154 NTSVYNILHEEDRKDFLKNLPKSTVNGVSWTNETQRQKSH-TFNCRMLMKT 203
+ S++N + E + + K L + S T E + K+ F C ML T
Sbjct: 151 DQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGT 201
Score = 39.3 bits (90), Expect = 0.027
Identities = 51/256 (19%), Positives = 96/256 (37%), Gaps = 11/256 (4%)
Query: 634 HSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGN 693
HS ++ SS K S +V+ PS + S+ H L +++ + +
Sbjct: 426 HSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRQH---LPAHEKMVQRRSSFSS 482
Query: 694 SPAEVAKITAEATGKDTSSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSK 753
+ + T S T+ + Q Q S + L L R +A
Sbjct: 483 QSINSQSVGSSLTQPVMSQATNLPIPQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEANIH 542
Query: 754 ELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILG-DLTSSDF 812
Q ++ + ++ + Q+ +P + + + SG+ N+ + ++
Sbjct: 543 RQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSSNIQQLAPINMQGQVV 602
Query: 813 YNNSISS--NGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPV 870
N I S N H+GT Q + Q +L S+QS Q++ +++ SL S + P+
Sbjct: 603 PTNQIQSGMNTGHIGTTQHMIQ-QQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAPL 661
Query: 871 KNISAFPMLPKQPMLG 886
N M+ QP G
Sbjct: 662 YN----TMVISQPAAG 673
Score = 38.5 bits (88), Expect = 0.046
Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 11/97 (11%)
Query: 1235 RQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAG 1294
+QQ + + QQQQQQ Q+QQ QQ Q Q Q Q + +PS +L+
Sbjct: 745 QQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQPPQQFLQTSRLLHGNPSTQLILSA 804
Query: 1295 ------PTMPQAPPQQFPYQPNYGMGQQ-----PDPA 1320
T PQ+ QQ Q + + PDP+
Sbjct: 805 AFPLQQSTFPQSHHQQHQSQQQQQLSRHRTDSLPDPS 841
Score = 33.9 bits (76), Expect = 1.1
Identities = 22/71 (30%), Positives = 26/71 (36%)
Query: 1249 QQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQ 1308
QQQQ Q QQQQQQ Q+QQ T P P L + P Q
Sbjct: 744 QQQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQPPQQFLQTSRLLHGNPSTQLILS 803
Query: 1309 PNYGMGQQPDP 1319
+ + Q P
Sbjct: 804 AAFPLQQSTFP 814
Score = 33.5 bits (75), Expect = 1.5
Identities = 60/278 (21%), Positives = 95/278 (34%), Gaps = 29/278 (10%)
Query: 1120 PPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQ 1179
P F Q + + +Q+ Q+ +H + +R +QL+M Q LQ
Sbjct: 508 PQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELR---KIQEQLQMVHGQGLQ 564
Query: 1180 GQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRV 1239
FL QS L ++G ++ ++ + + Q+V + +
Sbjct: 565 --MFLQQSNPGLNFGSVQLSSGNSSNIQQLAPIN---MQGQVVPTNQIQSGMNTGHIGTT 619
Query: 1240 AMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPP----NVTASPSMDGLLAGP 1295
M+QQQ Q Q QQ QQ QTQ+ P V + P+ ++ P
Sbjct: 620 QHMIQQQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAPLYNTMVISQPAAGSMVQIP 679
Query: 1296 -TMPQAPPQQFPY-------QPNYGMGQQ-------PDPAFGRVSSPPNAMMSSRMG--P 1338
+MPQ Q Q + GQQ A G V P +M + P
Sbjct: 680 SSMPQNSTQSAAVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYP 739
Query: 1339 SQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQ 1376
+ Q Q S+ Q + + L SQ Q
Sbjct: 740 TFATQQQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQ 777
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 77.4 bits (189), Expect = 9e-14
Identities = 88/324 (27%), Positives = 129/324 (39%), Gaps = 70/324 (21%)
Query: 1004 SNQLGSWPDGMLSMEQVSHGTQ----NRPL-LRNSLDDLVGPPSNLEGQSDERALLDQLH 1058
S + +W + ++ +++ NRP + + L L P NLE Q + Q H
Sbjct: 325 SEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHS---QQGH 381
Query: 1059 TLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQ 1118
T N +A ++ ++ + L+ +Q A Q Q Q +P
Sbjct: 382 T---NANAVLFSQV-------KVTPETHMLQQQQQAQQQQ--------------QQHPV- 416
Query: 1119 GPPMQGGFHLQGQS-PSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQR 1177
HLQ Q Q Q +P Q HP + + Q QQ+
Sbjct: 417 -------LHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQ------------QQQQQQQ 457
Query: 1178 LQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQ 1237
QF Q Q + ++ P + RP Q Q F + Q+ +L H +QQ
Sbjct: 458 AHPHQFSQQQLQFPQQQLHPPQQ----LHRPQQQLQP-FQQQHALQQQFHQLQQHQLQQQ 512
Query: 1238 RVAMMMQQQQQQQQQQQQQ-QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPT 1296
++A + QQ QQQQQQQ QQQQ Q+ QQQQQQQ Q+ + P S ++
Sbjct: 513 QLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQAL-------- 564
Query: 1297 MPQAPPQQFPYQPNYGMGQQPDPA 1320
Q PPQQ P Q QQP P+
Sbjct: 565 QHQVPPQQPPQQQQQ---QQPPPS 585
Score = 47.0 bits (110), Expect = 1e-04
Identities = 59/217 (27%), Positives = 83/217 (38%), Gaps = 21/217 (9%)
Query: 1142 MNQQGNFPLQGMHPRAN--IMRPRTNTPKQLRMQLQQRLQGQQFLN-----QSRQALELK 1194
+ QQ N QG H AN + TP+ +Q QQ+ Q QQ + Q +Q ++L+
Sbjct: 370 LEQQVNHSQQG-HTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQ 428
Query: 1195 MENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQ---QQQQQQ 1251
+ + PQQ Q+ ++ H F QQ++ QQ QQ +
Sbjct: 429 QQQQQQ-----ISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHR 483
Query: 1252 QQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNY 1311
QQQ Q QQQ QQQ Q Q + LL Q QQ Q
Sbjct: 484 PQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLL-----QQQQQQQIQQQQLQ 538
Query: 1312 GMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQ 1348
M QQ + + P+ +S+ Q P Q PQ
Sbjct: 539 RMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQ 575
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 76.6 bits (187), Expect = 2e-13
Identities = 86/287 (29%), Positives = 121/287 (42%), Gaps = 50/287 (17%)
Query: 1128 LQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRL---QGQQFL 1184
LQ Q+ S + Q+ PLQ + +M P+ TP+Q++ LQQ++ Q Q L
Sbjct: 66 LQQQTSGLKSPKSSDKQR---PLQ-VPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQAL 121
Query: 1185 NQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQ 1244
Q +QA+ L+ + ++ + QQ L+ Q++ Q+ Q
Sbjct: 122 LQQQQAVMLQQQQ--------LQEFYKKQQEQLHLQLLQQQQ-----------------Q 156
Query: 1245 QQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQ 1304
QQQQQQQQQQQQQQQQQQQQQQQQQQQQ Q + + Q QQ
Sbjct: 157 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ--QQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214
Query: 1305 FPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQA----ASIYQ------ 1354
+Q QQ +S ++S G + P+ PQA A I Q
Sbjct: 215 LVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 274
Query: 1355 ---SSEMKGWPSGNL---ARNSSFSQQQFAHQGNPAVYSMVHMNGSS 1395
S E G G L NSS + + +P + +NG S
Sbjct: 275 GVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQS 321
>gi|30795242 aryl hydrocarbon receptor nuclear translocator isoform
3 [Homo sapiens]
Length = 774
Score = 76.6 bits (187), Expect = 2e-13
Identities = 96/427 (22%), Positives = 176/427 (41%), Gaps = 68/427 (15%)
Query: 34 EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDD 93
E+RRR + + YI EL++++ KPDK IL+ V ++ ++ G T ++
Sbjct: 83 ERRRRNKMTAYITELSDMVPT----CSALARKPDKLTILRMAVSHMKSLRGTGNTSTD-- 136
Query: 94 DVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVN-RDGNIVFVSENVTQYLQYKQEDL 152
S + L L+L+A DGFLF+V+ G +V+VS++VT L Q +
Sbjct: 137 -------GSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEW 189
Query: 153 VNTSVYNILHEEDRKDFLKNLPKSTVNGV--------SWTNETQRQKS---------HTF 195
+++Y+ +H +D D L+ ++ N + + T + + Q+S +F
Sbjct: 190 FGSTLYDQVHPDD-VDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSF 248
Query: 196 NCRMLMKTPHDILEDINASPEMRQR--------------YETMQC---------FALSQP 232
CRM + +N +R R + + C +S P
Sbjct: 249 ICRMRCGSSSVDPVSVNRLSFVRNRCRNGLGSVKDGEPHFVVVHCTGYIKAWPPAGVSLP 308
Query: 233 RAMMEEGEDLQSCMICVARRITTGER--TFPSN---PESFITRHDLSGKVVNIDTNSLRS 287
E G+ + C++ + R T T SN P FI+RH++ G +D + +
Sbjct: 309 DDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNVCQPTEFISRHNIEGIFTFVDHRCVAT 368
Query: 288 -SMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQ 346
+P ++++ + I F D Q + Q L G + ++RF + + +
Sbjct: 369 VGYQP--QELLGKNIVEFCHPED-QQLLRDSFQQVVKLKGQVLSVMFRFRSKNQEWLWMR 425
Query: 347 TKSKLFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRP---PMAGCNSSVGGMSM 403
T S F+NP +++ + T+ + + P P RP P A +G +
Sbjct: 426 TSSFTFQNPYSDEIEYIICTN-TNVKNSSQEPRPTLSNTIQRPQLGPTANLPLEMGSGQL 484
Query: 404 SPNQGLQ 410
+P Q Q
Sbjct: 485 APRQQQQ 491
>gi|4502231 aryl hydrocarbon receptor nuclear translocator isoform 1
[Homo sapiens]
Length = 789
Score = 76.6 bits (187), Expect = 2e-13
Identities = 96/427 (22%), Positives = 176/427 (41%), Gaps = 68/427 (15%)
Query: 34 EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDD 93
E+RRR + + YI EL++++ KPDK IL+ V ++ ++ G T ++
Sbjct: 98 ERRRRNKMTAYITELSDMVPT----CSALARKPDKLTILRMAVSHMKSLRGTGNTSTD-- 151
Query: 94 DVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVN-RDGNIVFVSENVTQYLQYKQEDL 152
S + L L+L+A DGFLF+V+ G +V+VS++VT L Q +
Sbjct: 152 -------GSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEW 204
Query: 153 VNTSVYNILHEEDRKDFLKNLPKSTVNGV--------SWTNETQRQKS---------HTF 195
+++Y+ +H +D D L+ ++ N + + T + + Q+S +F
Sbjct: 205 FGSTLYDQVHPDD-VDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSF 263
Query: 196 NCRMLMKTPHDILEDINASPEMRQR--------------YETMQC---------FALSQP 232
CRM + +N +R R + + C +S P
Sbjct: 264 ICRMRCGSSSVDPVSVNRLSFVRNRCRNGLGSVKDGEPHFVVVHCTGYIKAWPPAGVSLP 323
Query: 233 RAMMEEGEDLQSCMICVARRITTGER--TFPSN---PESFITRHDLSGKVVNIDTNSLRS 287
E G+ + C++ + R T T SN P FI+RH++ G +D + +
Sbjct: 324 DDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNVCQPTEFISRHNIEGIFTFVDHRCVAT 383
Query: 288 -SMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQ 346
+P ++++ + I F D Q + Q L G + ++RF + + +
Sbjct: 384 VGYQP--QELLGKNIVEFCHPED-QQLLRDSFQQVVKLKGQVLSVMFRFRSKNQEWLWMR 440
Query: 347 TKSKLFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRP---PMAGCNSSVGGMSM 403
T S F+NP +++ + T+ + + P P RP P A +G +
Sbjct: 441 TSSFTFQNPYSDEIEYIICTN-TNVKNSSQEPRPTLSNTIQRPQLGPTANLPLEMGSGQL 499
Query: 404 SPNQGLQ 410
+P Q Q
Sbjct: 500 APRQQQQ 506
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 76.6 bits (187), Expect = 2e-13
Identities = 64/201 (31%), Positives = 84/201 (41%), Gaps = 22/201 (10%)
Query: 1210 MQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQ------QQQQQQQQQQQQQQQQQQ 1263
M P L+ Q + S L H Q V++ Q Q QQQQQQQQQQQQQQQQ
Sbjct: 217 MDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQ 276
Query: 1264 QQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGM----GQQPDP 1319
QQQQQQQQQ QA P + P G P Q P P + QP P
Sbjct: 277 QQQQQQQQQLQARPPQQHQQQQPQ------GIRPQFTAPTQVPVPPGWNQLPSGALQPPP 330
Query: 1320 A---FGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSE-MKGWPSGNLARNSSFSQQ 1375
A G +++ + GP Q + P A++ S +P G ++ +S +
Sbjct: 331 AQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFG--SQQASQAHT 388
Query: 1376 QFAHQGNPAVYSMVHMNGSSG 1396
F NP ++ M G
Sbjct: 389 NFPQMSNPGQFTAPQMKSLQG 409
Score = 60.5 bits (145), Expect = 1e-08
Identities = 145/638 (22%), Positives = 222/638 (34%), Gaps = 147/638 (23%)
Query: 816 SISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISA 875
S+ + ++ G K+ G L++ S+ +++ P + P GS + +
Sbjct: 334 SLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPP----PPYPFGSQQASQAHTN 389
Query: 876 FPMLPKQPMLGGNPRMMDSQENYGSSMGGPNRNVTVTQTPSSGDWGLPNSKAGRME--PM 933
FP + NP + + S GGP+R T Q P + +S + + P
Sbjct: 390 FPQM-------SNPGQFTAPQ-MKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPA 441
Query: 934 NSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGARPVLQQ----------QQQMLQ 983
+S ++ + PRP +P + S PG P++QQ QQQ
Sbjct: 442 SSPTVNQTQQQMG---PRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPN 498
Query: 984 MRPGEIPMGMGANP--------YGQAAASNQLGSWPD------------GMLSMEQVSH- 1022
P + G+G P GQA + G P + + + V H
Sbjct: 499 QGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHA 558
Query: 1023 GTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELV 1082
G Q +N + GPP+ ++ L +H ++N A G+P++
Sbjct: 559 GGQGAGPPQNQMQVSHGPPNMMQPS------LMGIHGNMNNQQA-------GTSGVPQV- 604
Query: 1083 NQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNS---MM 1139
QGQ Q G++ Q P+QG +Q L Q+P S +M
Sbjct: 605 --------NLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLM 656
Query: 1140 NQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPT 1199
Q N P Q + P M P PKQ+ Q QG Q + Q
Sbjct: 657 PQGQMMVNPPSQNLGPSPQRMTP----PKQMLSQ-----QGPQMMAPHNQ---------- 697
Query: 1200 AGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQ 1259
MM PQ Q++ Q++ M++Q Q Q +QQ
Sbjct: 698 ---------MMGPQ-----GQVLLQQN--------------PMIEQIMTNQMQGNKQQFN 729
Query: 1260 QQQQQQQQQQQQQTQAFSPPPNVTAS-PSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPD 1318
Q Q Q P PN+ + G ++G +PQ P P+ MG Q
Sbjct: 730 TQNQSNVMPGPAQIMR-GPTPNMQGNMVQFTGQMSGQMLPQQGPVN--NSPSQVMGIQ-- 784
Query: 1319 PAFGRVSSPPNAMMSSRMGPSQNPMMQH--PQAASIYQSSEMKGWPSGNLARNSSFSQQQ 1376
G+V PP GPS + QH P + S + P ++ + +
Sbjct: 785 ---GQVLRPP--------GPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHV 833
Query: 1377 FAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMG 1414
A QGN A N SGH N P SG P G
Sbjct: 834 QAMQGNSA-----SGNHFSGHGMSFN---APFSGAPNG 863
Score = 50.8 bits (120), Expect = 9e-06
Identities = 72/293 (24%), Positives = 100/293 (34%), Gaps = 42/293 (14%)
Query: 1146 GNFPLQGMHPRANI-MRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAA 1204
GN M P N ++PRT P + L G QS + L + +
Sbjct: 188 GNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVS 247
Query: 1205 VMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQ 1264
V R M L Q Q+ ++ +QQ+ +Q + QQ QQQQ Q + Q
Sbjct: 248 VNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFT 307
Query: 1265 QQQQ-------QQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAP-----PQQFPYQPNYG 1312
Q Q + A PPP A S+ + A +AP QQ +P+
Sbjct: 308 APTQVPVPPGWNQLPSGALQPPP---AQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLA 364
Query: 1313 MGQQPDPAFGRVSSPPNAMMSSRMGPSQN----PMMQHPQAASIYQSSEMKGWPS----- 1363
Q P S PP SQ P M +P + Q ++G PS
Sbjct: 365 TVQTP-------SHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTP 417
Query: 1364 ---GNLARNSSFSQQQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPM 1413
+L S S QG+PA V+ Q M P P P+
Sbjct: 418 LQQPHLTNKSPASSPSSFQQGSPASSPTVNQT-------QQQMGPRPPQNNPL 463
Score = 47.8 bits (112), Expect = 8e-05
Identities = 148/649 (22%), Positives = 221/649 (34%), Gaps = 124/649 (19%)
Query: 824 LGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQP 883
LG +G ++ L +Q+ ++ V ++ P+ G+S V+ + FPM
Sbjct: 122 LGILSVQIEGEGAINLALAQN-------RSQDVRMNGPMGAGNS--VRMEAGFPMASGPG 172
Query: 884 MLG-GNPR--MMDSQENYGSSMGGPNRNVTVT-QTPSSGDWGLPNSKAGRMEPMNSN--- 936
++ NP M+ N SSM P N + +TP P S++ M+P+ S
Sbjct: 173 IIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPR------PASQSDAMDPLLSGLHI 226
Query: 937 -SMGRPGGDYN--------TSLPRPALGGSIPTLPLRSNSIPGARPVLQQQQQM-----L 982
P G S+ R + P L + + QQQQQ L
Sbjct: 227 QQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQL 286
Query: 983 QMRPGEIPMGMGANPYG---QAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVG 1039
Q RP + P G Q A Q+ P Q+ G P + SL +
Sbjct: 287 QARPPQ--QHQQQQPQGIRPQFTAPTQVPVPP----GWNQLPSGALQPPPAQGSLGTMTA 340
Query: 1040 P--------PSNLEGQSDERALLDQLHTLLSNTD--ATGLEEIDRA-LGIPELVNQGQAL 1088
P ++ Q R L + T G ++ +A P++ N GQ
Sbjct: 341 NQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFT 400
Query: 1089 EPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQ--- 1145
P+ + QG + V + PA P Q SP+ + +NQ QQ
Sbjct: 401 APQMKSLQGGPSRVPTPLQQPHLTNKSPASSPS-----SFQQGSPASSPTVNQTQQQMGP 455
Query: 1146 ---GNFPL-QGMH-----PRANIMRPRTNTPKQ-LRMQLQQRLQGQQFLNQSRQALELKM 1195
N PL QG P N M + N P + MQ Q QG Q L+ + ++
Sbjct: 456 RPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRL 515
Query: 1196 ENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQ 1255
+ G Q F+ Q+ + Q Q
Sbjct: 516 PPGFSAG--------QANPNFMQGQVPS---------------TTATTPGNSGAPQLQAN 552
Query: 1256 QQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQA--------------- 1300
Q Q Q Q Q Q PPN+ PS+ G+ QA
Sbjct: 553 QNVQHAGGQGAGPPQNQMQVSHGPPNM-MQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQG 611
Query: 1301 PPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKG 1360
PQQ P GM QQ P+ G++ + P QNPM+ +A + Q M
Sbjct: 612 QPQQGPPSQLMGMHQQIVPSQGQM-----VQQQGTLNP-QNPMIL-SRAQLMPQGQMMVN 664
Query: 1361 WPSGNLA---RNSSFSQQQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPM 1406
PS NL + + +Q + QG + M G G + + NPM
Sbjct: 665 PPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQV-LLQQNPM 712
Score = 44.3 bits (103), Expect = 8e-04
Identities = 132/606 (21%), Positives = 205/606 (33%), Gaps = 97/606 (16%)
Query: 839 LKSSQSVQ-----SIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMD 893
L+++Q+VQ PP N+ P ++ P + I M +Q G P++
Sbjct: 549 LQANQNVQHAGGQGAGPPQNQMQVSHGPPNM-MQPSLMGIHG-NMNNQQAGTSGVPQVNL 606
Query: 894 SQENYGSSMGGPNRNVTVTQ--TPSSGDWGLPNSKAGRMEPMNSNSMGR----PGGDYNT 947
S G P++ + + Q PS G + G + P N + R P G
Sbjct: 607 SNMQGQPQQGPPSQLMGMHQQIVPSQGQMV---QQQGTLNPQNPMILSRAQLMPQGQMMV 663
Query: 948 SLPRPALGGSIPTLPLRSNSIPGARPVLQQQQQML----QMRPGEIPMGMGANPYGQAAA 1003
+ P LG P P + + QQ QM+ QM + + + NP +
Sbjct: 664 NPPSQNLG------PSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIM 717
Query: 1004 SNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSN 1063
+NQ+ + Q + ++R ++ G GQ + L Q S
Sbjct: 718 TNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSP 777
Query: 1064 TDATGLE-EIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPM 1122
+ G++ ++ R G + Q Q +P A + MM + P M
Sbjct: 778 SQVMGIQGQVLRPPGPSPHMAQ-QHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAM 836
Query: 1123 QG----GFHLQGQSPSFNSMM------NQMN----------------------------Q 1144
QG G H G SFN+ NQM+
Sbjct: 837 QGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDIS 896
Query: 1145 QGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQ-------GQQFLNQ----SRQALEL 1193
G+F + N +P+ P + + QQ L G + +Q Q + L
Sbjct: 897 AGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINL 956
Query: 1194 KMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSH-----HFRQQRVAMMMQQQQQ 1248
P + RP P Q + + + Q +L+ H QQ+ + QQQQ
Sbjct: 957 DNSGPKLPEFS-NRPPGYPSQP-VEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQ 1014
Query: 1249 QQQQQQQQQQQQQQQQQQQ----QQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQ 1304
Q Q QQQQQQQQQ QQ ++ P + P L P + P QQ
Sbjct: 1015 PPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPL--NPDSQRMPMQQ 1072
Query: 1305 FPYQPNYGMGQ-----QPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMK 1359
P Q P P R+ P N + S + + PQ S +EM
Sbjct: 1073 SGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGS--NSRKMVYQESPQNPSSSPLAEMA 1130
Query: 1360 GWPSGN 1365
P +
Sbjct: 1131 SLPEAS 1136
Score = 30.8 bits (68), Expect = 9.7
Identities = 54/241 (22%), Positives = 80/241 (33%), Gaps = 50/241 (20%)
Query: 818 SSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRP--PYNRAVSLDSPVSVGSSPPVKNISA 875
S++G+H F S +Q P P N+ V+L SP+ V +
Sbjct: 840 SASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGH 899
Query: 876 FPMLPKQPMLGGNP--------RMMDSQENYGSSMGGPNRNVTVTQTPSSGDWGLPNSKA 927
F + KQ N + +SQ++ + P Q P G+ G+ +
Sbjct: 900 FGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNS 959
Query: 928 GRMEPMNSNSMGRPGG-------------------DYNTSLPRPALGGSIPTLPLRSNSI 968
G P SN RP G + P+P P LP +
Sbjct: 960 GPKLPEFSN---RPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPP 1016
Query: 969 PGARPVLQQQQQ---------MLQMRPGEIPMGMG---------ANPYGQAAASNQLGSW 1010
P ++P QQQQQ M+Q P + + + NP Q Q GS
Sbjct: 1017 PPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSV 1076
Query: 1011 P 1011
P
Sbjct: 1077 P 1077
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 76.3 bits (186), Expect = 2e-13
Identities = 78/256 (30%), Positives = 109/256 (42%), Gaps = 46/256 (17%)
Query: 1159 IMRPRTNTPKQLRMQLQQRL---QGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQG 1215
+M P+ TP+Q++ LQQ++ Q Q L Q +QA+ L+ + ++ + QQ
Sbjct: 1 MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQ--------LQEFYKKQQE 52
Query: 1216 FLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQA 1275
L+ Q++ Q+ QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ Q
Sbjct: 53 QLHLQLLQQQQ-----------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ- 94
Query: 1276 FSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSR 1335
+ + Q QQ +Q QQ +S ++S
Sbjct: 95 -QQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIP 153
Query: 1336 MGPSQNPMMQHPQA----ASIYQ---------SSEMKGWPSGNL---ARNSSFSQQQFAH 1379
G + P+ PQA A I Q S E G G L NSS +
Sbjct: 154 PGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTS 213
Query: 1380 QGNPAVYSMVHMNGSS 1395
+ +P + +NG S
Sbjct: 214 KASPPITHHSIVNGQS 229
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 76.3 bits (186), Expect = 2e-13
Identities = 78/256 (30%), Positives = 109/256 (42%), Gaps = 46/256 (17%)
Query: 1159 IMRPRTNTPKQLRMQLQQRL---QGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQG 1215
+M P+ TP+Q++ LQQ++ Q Q L Q +QA+ L+ + ++ + QQ
Sbjct: 118 MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQ--------LQEFYKKQQE 169
Query: 1216 FLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQA 1275
L+ Q++ Q+ QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ Q
Sbjct: 170 QLHLQLLQQQQ-----------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ- 211
Query: 1276 FSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSR 1335
+ + Q QQ +Q QQ +S ++S
Sbjct: 212 -QQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIP 270
Query: 1336 MGPSQNPMMQHPQA----ASIYQ---------SSEMKGWPSGNL---ARNSSFSQQQFAH 1379
G + P+ PQA A I Q S E G G L NSS +
Sbjct: 271 PGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTS 330
Query: 1380 QGNPAVYSMVHMNGSS 1395
+ +P + +NG S
Sbjct: 331 KASPPITHHSIVNGQS 346
Score = 47.0 bits (110), Expect = 1e-04
Identities = 29/74 (39%), Positives = 43/74 (58%), Gaps = 6/74 (8%)
Query: 1204 AVMRPMM---QPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQ 1260
A+M P + Q Q L Q+++ + + L +QQ+ M+ QQQ Q+ ++QQ+Q
Sbjct: 117 AMMTPQVITPQQMQQILQQQVLSPQQLQAL---LQQQQAVMLQQQQLQEFYKKQQEQLHL 173
Query: 1261 QQQQQQQQQQQQTQ 1274
Q QQQQQQQQQ Q
Sbjct: 174 QLLQQQQQQQQQQQ 187
Score = 34.7 bits (78), Expect = 0.67
Identities = 40/151 (26%), Positives = 55/151 (36%), Gaps = 45/151 (29%)
Query: 1165 NTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQ------------- 1211
+T + L +Q QQ LQ + L +Q LK + RP+ +
Sbjct: 45 STVELLHLQQQQALQAARQLLLQQQTSGLKSPK----SSDKQRPLQELLPETKLCICGHS 100
Query: 1212 -----PQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQ------- 1259
P F VA + ++++ QQ + + QQ Q QQQQ
Sbjct: 101 SGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQL 160
Query: 1260 ----------------QQQQQQQQQQQQQTQ 1274
QQQQQQQQQQQQQ Q
Sbjct: 161 QEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQ 191
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 76.3 bits (186), Expect = 2e-13
Identities = 200/959 (20%), Positives = 328/959 (34%), Gaps = 187/959 (19%)
Query: 482 ISPRNRGSPKIASHQFSPVAGVHSPMASSGN----TGNHSFSSSSLSALQAISEGVGTSL 537
++P + K +S F V S + N GN SFSS S S L + +E
Sbjct: 531 VTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLPSENE------ 584
Query: 538 LSTLSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKE 597
PK N + Q +S Q P Q P ++ Q ++ + +
Sbjct: 585 --KQQQIQPKAYNPETLTTIQTQDIS-QPGTFPAVSASSQLPNSDALLQQATQFQTRETQ 641
Query: 598 SKESSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPS 657
S+E L+S G L LT +S + SPL + T
Sbjct: 642 SREI-----------LQSDGTVVNLSQLTEASQQQ-----QQSPLQEQAQ------TLQQ 679
Query: 658 GVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPA-EVAKITAEATGKDTSSITSC 716
+SS+ +S S + ++ Q + +G+S + ++ + EA + +S + S
Sbjct: 680 QISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSA 739
Query: 717 GDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPS 776
DGN QEQLS + ++SQ S P
Sbjct: 740 PDGNENVQEQLSAD-------------------------------IFQQVSQIQSGVSPG 768
Query: 777 SSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNS 836
+P + T G +++ N++S+ +QQV + + +
Sbjct: 769 MFSSTEPTVHTRPDNLLPGRAESVHPQS---------ENTLSNQQQQQQQQQQVMESSAA 819
Query: 837 LGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPK----QPMLGGNPRMM 892
+ ++ QS+ A + S + ++ N+ P+ + L N M
Sbjct: 820 MVMEMQQSI------CQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQ 873
Query: 893 DSQENYGSS---MGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSL 949
E + S G T Q + G S +G E + + + T +
Sbjct: 874 MQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMV 933
Query: 950 PRPALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGS 1009
G + P + L S++ + M G G G G S Q G+
Sbjct: 934 QMQHSGDNQPQVNLFSST----------KSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGN 983
Query: 1010 WPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGL 1069
+ ++Q SH +N + D NL ++ + S T T
Sbjct: 984 F------LQQSSHSQAQLFHPQNPIADA----QNLSQETQGSLFHSPNPIVHSQTSTTSS 1033
Query: 1070 EEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQ 1129
E++ + F Q + L G + P Q
Sbjct: 1034 EQMQPPM------------------FHSQSTIAV------LQGSSVPQD---QQSTNIFL 1066
Query: 1130 GQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQ---QRLQGQQFLNQ 1186
QSP N N + Q+ F + ++ +N+ +Q Q Q +Q +
Sbjct: 1067 SQSPMNNLQTNTVAQEAFFAAPNS---ISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQE 1123
Query: 1187 SRQALELKMENP-TAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQ 1245
Q + + P A G+ PM Q QQG + F+ Q + MQ
Sbjct: 1124 QAQPPQQGLFQPQVALGSLPPNPMPQSQQGTM----------------FQSQHSIVAMQS 1167
Query: 1246 QQQQQQQQQQQQQQQQQQQQQQQ----QQQQTQAF-----SPPPNVTASPSMDGLLAGPT 1296
Q+QQQQQQQQQQQQQQQQQ Q T A PPPN+ +P+ + +
Sbjct: 1168 NSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPM---AN 1224
Query: 1297 MPQAPPQQFPYQPNYG-MGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQS 1355
Q F Q N M Q+ P + S +++ + GP+Q+ Q P S Q
Sbjct: 1225 QEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNP--GPTQSESSQTPLFHSSPQI 1282
Query: 1356 SEMKGWPSGNLARNSSFSQQQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPM--PMSGMP 1412
++G PS +QQ +PA S + +S + M +P+ P + MP
Sbjct: 1283 QLVQGSPSS--------QEQQVTLFLSPASMSALQ---TSINQQDMQQSPLYSPQNNMP 1330
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 76.3 bits (186), Expect = 2e-13
Identities = 200/959 (20%), Positives = 328/959 (34%), Gaps = 187/959 (19%)
Query: 482 ISPRNRGSPKIASHQFSPVAGVHSPMASSGN----TGNHSFSSSSLSALQAISEGVGTSL 537
++P + K +S F V S + N GN SFSS S S L + +E
Sbjct: 607 VTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLPSENE------ 660
Query: 538 LSTLSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKE 597
PK N + Q +S Q P Q P ++ Q ++ + +
Sbjct: 661 --KQQQIQPKAYNPETLTTIQTQDIS-QPGTFPAVSASSQLPNSDALLQQATQFQTRETQ 717
Query: 598 SKESSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPS 657
S+E L+S G L LT +S + SPL + T
Sbjct: 718 SREI-----------LQSDGTVVNLSQLTEASQQQ-----QQSPLQEQAQ------TLQQ 755
Query: 658 GVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPA-EVAKITAEATGKDTSSITSC 716
+SS+ +S S + ++ Q + +G+S + ++ + EA + +S + S
Sbjct: 756 QISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSA 815
Query: 717 GDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPS 776
DGN QEQLS + ++SQ S P
Sbjct: 816 PDGNENVQEQLSAD-------------------------------IFQQVSQIQSGVSPG 844
Query: 777 SSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNS 836
+P + T G +++ N++S+ +QQV + + +
Sbjct: 845 MFSSTEPTVHTRPDNLLPGRAESVHPQS---------ENTLSNQQQQQQQQQQVMESSAA 895
Query: 837 LGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPK----QPMLGGNPRMM 892
+ ++ QS+ A + S + ++ N+ P+ + L N M
Sbjct: 896 MVMEMQQSI------CQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQ 949
Query: 893 DSQENYGSS---MGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSL 949
E + S G T Q + G S +G E + + + T +
Sbjct: 950 MQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMV 1009
Query: 950 PRPALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGS 1009
G + P + L S++ + M G G G G S Q G+
Sbjct: 1010 QMQHSGDNQPQVNLFSST----------KSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGN 1059
Query: 1010 WPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGL 1069
+ ++Q SH +N + D NL ++ + S T T
Sbjct: 1060 F------LQQSSHSQAQLFHPQNPIADA----QNLSQETQGSLFHSPNPIVHSQTSTTSS 1109
Query: 1070 EEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQ 1129
E++ + F Q + L G + P Q
Sbjct: 1110 EQMQPPM------------------FHSQSTIAV------LQGSSVPQD---QQSTNIFL 1142
Query: 1130 GQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQ---QRLQGQQFLNQ 1186
QSP N N + Q+ F + ++ +N+ +Q Q Q +Q +
Sbjct: 1143 SQSPMNNLQTNTVAQEAFFAAPNS---ISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQE 1199
Query: 1187 SRQALELKMENP-TAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQ 1245
Q + + P A G+ PM Q QQG + F+ Q + MQ
Sbjct: 1200 QAQPPQQGLFQPQVALGSLPPNPMPQSQQGTM----------------FQSQHSIVAMQS 1243
Query: 1246 QQQQQQQQQQQQQQQQQQQQQQQ----QQQQTQAF-----SPPPNVTASPSMDGLLAGPT 1296
Q+QQQQQQQQQQQQQQQQQ Q T A PPPN+ +P+ + +
Sbjct: 1244 NSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPM---AN 1300
Query: 1297 MPQAPPQQFPYQPNYG-MGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQS 1355
Q F Q N M Q+ P + S +++ + GP+Q+ Q P S Q
Sbjct: 1301 QEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNP--GPTQSESSQTPLFHSSPQI 1358
Query: 1356 SEMKGWPSGNLARNSSFSQQQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPM--PMSGMP 1412
++G PS +QQ +PA S + +S + M +P+ P + MP
Sbjct: 1359 QLVQGSPSS--------QEQQVTLFLSPASMSALQ---TSINQQDMQQSPLYSPQNNMP 1406
>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
sapiens]
Length = 1548
Score = 76.3 bits (186), Expect = 2e-13
Identities = 200/959 (20%), Positives = 328/959 (34%), Gaps = 187/959 (19%)
Query: 482 ISPRNRGSPKIASHQFSPVAGVHSPMASSGN----TGNHSFSSSSLSALQAISEGVGTSL 537
++P + K +S F V S + N GN SFSS S S L + +E
Sbjct: 624 VTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLPSENE------ 677
Query: 538 LSTLSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKE 597
PK N + Q +S Q P Q P ++ Q ++ + +
Sbjct: 678 --KQQQIQPKAYNPETLTTIQTQDIS-QPGTFPAVSASSQLPNSDALLQQATQFQTRETQ 734
Query: 598 SKESSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPS 657
S+E L+S G L LT +S + SPL + T
Sbjct: 735 SREI-----------LQSDGTVVNLSQLTEASQQQ-----QQSPLQEQAQ------TLQQ 772
Query: 658 GVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPA-EVAKITAEATGKDTSSITSC 716
+SS+ +S S + ++ Q + +G+S + ++ + EA + +S + S
Sbjct: 773 QISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSA 832
Query: 717 GDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPS 776
DGN QEQLS + ++SQ S P
Sbjct: 833 PDGNENVQEQLSAD-------------------------------IFQQVSQIQSGVSPG 861
Query: 777 SSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNS 836
+P + T G +++ N++S+ +QQV + + +
Sbjct: 862 MFSSTEPTVHTRPDNLLPGRAESVHPQS---------ENTLSNQQQQQQQQQQVMESSAA 912
Query: 837 LGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPK----QPMLGGNPRMM 892
+ ++ QS+ A + S + ++ N+ P+ + L N M
Sbjct: 913 MVMEMQQSI------CQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQ 966
Query: 893 DSQENYGSS---MGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSL 949
E + S G T Q + G S +G E + + + T +
Sbjct: 967 MQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMV 1026
Query: 950 PRPALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGS 1009
G + P + L S++ + M G G G G S Q G+
Sbjct: 1027 QMQHSGDNQPQVNLFSST----------KSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGN 1076
Query: 1010 WPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGL 1069
+ ++Q SH +N + D NL ++ + S T T
Sbjct: 1077 F------LQQSSHSQAQLFHPQNPIADA----QNLSQETQGSLFHSPNPIVHSQTSTTSS 1126
Query: 1070 EEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQ 1129
E++ + F Q + L G + P Q
Sbjct: 1127 EQMQPPM------------------FHSQSTIAV------LQGSSVPQD---QQSTNIFL 1159
Query: 1130 GQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQ---QRLQGQQFLNQ 1186
QSP N N + Q+ F + ++ +N+ +Q Q Q +Q +
Sbjct: 1160 SQSPMNNLQTNTVAQEAFFAAPNS---ISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQE 1216
Query: 1187 SRQALELKMENP-TAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQ 1245
Q + + P A G+ PM Q QQG + F+ Q + MQ
Sbjct: 1217 QAQPPQQGLFQPQVALGSLPPNPMPQSQQGTM----------------FQSQHSIVAMQS 1260
Query: 1246 QQQQQQQQQQQQQQQQQQQQQQQ----QQQQTQAF-----SPPPNVTASPSMDGLLAGPT 1296
Q+QQQQQQQQQQQQQQQQQ Q T A PPPN+ +P+ + +
Sbjct: 1261 NSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPM---AN 1317
Query: 1297 MPQAPPQQFPYQPNYG-MGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQS 1355
Q F Q N M Q+ P + S +++ + GP+Q+ Q P S Q
Sbjct: 1318 QEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNP--GPTQSESSQTPLFHSSPQI 1375
Query: 1356 SEMKGWPSGNLARNSSFSQQQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPM--PMSGMP 1412
++G PS +QQ +PA S + +S + M +P+ P + MP
Sbjct: 1376 QLVQGSPSS--------QEQQVTLFLSPASMSALQ---TSINQQDMQQSPLYSPQNNMP 1423
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,468,064
Number of Sequences: 37866
Number of extensions: 3173593
Number of successful extensions: 36090
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 403
Number of HSP's successfully gapped in prelim test: 475
Number of HSP's that attempted gapping in prelim test: 14658
Number of HSP's gapped (non-prelim): 7057
length of query: 1420
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1305
effective length of database: 13,892,928
effective search space: 18130271040
effective search space used: 18130271040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.