Search of human proteins with 31742492

Search of human proteins with 31742492

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31742492 Nedd4 binding protein 2 [Homo sapiens]
         (1770 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31742492 Nedd4 binding protein 2 [Homo sapiens]                   3543   0.0  
gi|7656971 phosphonoformate immuno-associated protein 5 isoform ...   184   9e-46
gi|119226224 NEDD4 binding protein 2-like 1 isoform 1 [Homo sapi...   182   3e-45
gi|119226227 NEDD4 binding protein 2-like 1 isoform 2 [Homo sapi...   120   1e-26
gi|157278100 phosphonoformate immuno-associated protein 5 isofor...   112   4e-24
gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo s...    55   5e-07
gi|146134388 YLP motif containing 1 [Homo sapiens]                     50   1e-05
gi|210032580 SET domain containing 1B [Homo sapiens]                   47   2e-04
gi|110349721 titin isoform novex-3 [Homo sapiens]                      44   0.001
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    44   0.001
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              38   0.076
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           37   0.13 
gi|114431248 hypothetical protein LOC205717 [Homo sapiens]             37   0.17 
gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]             37   0.17 
gi|21071077 dishevelled-associated activator of morphogenesis 1 ...    37   0.17 
gi|4507691 transformation/transcription domain-associated protei...    37   0.22 
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa...    37   0.22 
gi|117676384 splicing factor, arginine/serine-rich 2, interactin...    36   0.29 
gi|197245373 proline rich 22 isoform 1 [Homo sapiens]                  36   0.38 
gi|23503299 proline rich 22 isoform 2 [Homo sapiens]                   36   0.38 
gi|221316699 maltase-glucoamylase [Homo sapiens]                       36   0.38 
gi|45238858 WD repeat domain 44 protein [Homo sapiens]                 36   0.38 
gi|120952764 mastermind-like domain containing 1 [Homo sapiens]        35   0.50 
gi|33356179 transcription termination factor, RNA polymerase I [...    35   0.65 
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    35   0.65 
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    35   0.65 
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    35   0.65 
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]          35   0.65 
gi|195947369 junction-mediating and regulatory protein [Homo sap...    35   0.65 
gi|39777606 Rho guanine nucleotide exchange factor 1 isoform 1 [...    35   0.65 

>gi|31742492 Nedd4 binding protein 2 [Homo sapiens]
          Length = 1770

 Score = 3543 bits (9186), Expect = 0.0
 Identities = 1770/1770 (100%), Positives = 1770/1770 (100%)

Query: 1    MPRRRKNLGGNPFRKTANPKEVVVSSVASREEPTTTLPSMGETKVDQEELFTSISEIFSD 60
            MPRRRKNLGGNPFRKTANPKEVVVSSVASREEPTTTLPSMGETKVDQEELFTSISEIFSD
Sbjct: 1    MPRRRKNLGGNPFRKTANPKEVVVSSVASREEPTTTLPSMGETKVDQEELFTSISEIFSD 60

Query: 61   LDPDVVYLMLSECDFKVENAMDCLLELSATDTKIEESSSQSFVASENQVGAAESKIMEKR 120
            LDPDVVYLMLSECDFKVENAMDCLLELSATDTKIEESSSQSFVASENQVGAAESKIMEKR
Sbjct: 61   LDPDVVYLMLSECDFKVENAMDCLLELSATDTKIEESSSQSFVASENQVGAAESKIMEKR 120

Query: 121  PEEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFI 180
            PEEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFI
Sbjct: 121  PEEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFI 180

Query: 181  NPDSSNMTPIFSTQNMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYP 240
            NPDSSNMTPIFSTQNMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYP
Sbjct: 181  NPDSSNMTPIFSTQNMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYP 240

Query: 241  EDSLLSSSLNVASDSIAGCSSLNQKQKELLESECVEAQFSEAPVDLDASEPQACLNLPGL 300
            EDSLLSSSLNVASDSIAGCSSLNQKQKELLESECVEAQFSEAPVDLDASEPQACLNLPGL
Sbjct: 241  EDSLLSSSLNVASDSIAGCSSLNQKQKELLESECVEAQFSEAPVDLDASEPQACLNLPGL 300

Query: 301  DLPGTGGDQKSTRVSDVFLPSEGFNFKPHKHPELPTKGKDVSYCPVLAPLPLLLPPPPPP 360
            DLPGTGGDQKSTRVSDVFLPSEGFNFKPHKHPELPTKGKDVSYCPVLAPLPLLLPPPPPP
Sbjct: 301  DLPGTGGDQKSTRVSDVFLPSEGFNFKPHKHPELPTKGKDVSYCPVLAPLPLLLPPPPPP 360

Query: 361  PMWNPMIPAFDLFQGNHGFVAPVVTTAAHWRSVNYTFPPSVISHTSPTKVWRNKDGTSAY 420
            PMWNPMIPAFDLFQGNHGFVAPVVTTAAHWRSVNYTFPPSVISHTSPTKVWRNKDGTSAY
Sbjct: 361  PMWNPMIPAFDLFQGNHGFVAPVVTTAAHWRSVNYTFPPSVISHTSPTKVWRNKDGTSAY 420

Query: 421  QVQETPVSQVVRKKTSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYING 480
            QVQETPVSQVVRKKTSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYING
Sbjct: 421  QVQETPVSQVVRKKTSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYING 480

Query: 481  QYQFDVKYLGEAHEWNQNRAKEAFEKKISPIIIDNTNLQAWEMKPYVALSQKHKYKVLFR 540
            QYQFDVKYLGEAHEWNQNRAKEAFEKKISPIIIDNTNLQAWEMKPYVALSQKHKYKVLFR
Sbjct: 481  QYQFDVKYLGEAHEWNQNRAKEAFEKKISPIIIDNTNLQAWEMKPYVALSQKHKYKVLFR 540

Query: 541  EPDTWWKFKPKELARRNIHGVSKEKITRMLEHYQRFVSVPIIMSSSVPEKIERIELCAYS 600
            EPDTWWKFKPKELARRNIHGVSKEKITRMLEHYQRFVSVPIIMSSSVPEKIERIELCAYS
Sbjct: 541  EPDTWWKFKPKELARRNIHGVSKEKITRMLEHYQRFVSVPIIMSSSVPEKIERIELCAYS 600

Query: 601  CEDRSTSPRDDEDIISEKEENILSLSLKHLEFTEEKNLDVTKETMLPENVAYLSNADLNK 660
            CEDRSTSPRDDEDIISEKEENILSLSLKHLEFTEEKNLDVTKETMLPENVAYLSNADLNK
Sbjct: 601  CEDRSTSPRDDEDIISEKEENILSLSLKHLEFTEEKNLDVTKETMLPENVAYLSNADLNK 660

Query: 661  RRKEISDMNPSIQSALILETPHMYFSDSESKLQATDKSENEQIEMVAVKGYSKTDTDSSM 720
            RRKEISDMNPSIQSALILETPHMYFSDSESKLQATDKSENEQIEMVAVKGYSKTDTDSSM
Sbjct: 661  RRKEISDMNPSIQSALILETPHMYFSDSESKLQATDKSENEQIEMVAVKGYSKTDTDSSM 720

Query: 721  ERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERATVTKKAFGKQKSKSTLEKFP 780
            ERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERATVTKKAFGKQKSKSTLEKFP
Sbjct: 721  ERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERATVTKKAFGKQKSKSTLEKFP 780

Query: 781  RHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDKKYNYPQSHKLVNSVSVNTDCVQQ 840
            RHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDKKYNYPQSHKLVNSVSVNTDCVQQ
Sbjct: 781  RHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDKKYNYPQSHKLVNSVSVNTDCVQQ 840

Query: 841  RGSPHESVEDGRKSQCDDASEPLNSYKYDAYKNIDKNSFNIMGDWPSSDSLAQREHRSRM 900
            RGSPHESVEDGRKSQCDDASEPLNSYKYDAYKNIDKNSFNIMGDWPSSDSLAQREHRSRM
Sbjct: 841  RGSPHESVEDGRKSQCDDASEPLNSYKYDAYKNIDKNSFNIMGDWPSSDSLAQREHRSRM 900

Query: 901  PKTGLSEPNLEIGTNDKMNEISLSTAHEACWGTSSQKLKTLGSSNLGSSEMLLSEMTCES 960
            PKTGLSEPNLEIGTNDKMNEISLSTAHEACWGTSSQKLKTLGSSNLGSSEMLLSEMTCES
Sbjct: 901  PKTGLSEPNLEIGTNDKMNEISLSTAHEACWGTSSQKLKTLGSSNLGSSEMLLSEMTCES 960

Query: 961  QTCLSKKSHGQHTSLPLTFTNSAPTVSGVVEPQTLAECQEQMPKRDPGKEVGMCTQTEPQ 1020
            QTCLSKKSHGQHTSLPLTFTNSAPTVSGVVEPQTLAECQEQMPKRDPGKEVGMCTQTEPQ
Sbjct: 961  QTCLSKKSHGQHTSLPLTFTNSAPTVSGVVEPQTLAECQEQMPKRDPGKEVGMCTQTEPQ 1020

Query: 1021 DFALLWKIEKNKISISDSIKVLTGRLDGFKPKVFNINTKSDVQEAIPYRVMYDKSTFVEE 1080
            DFALLWKIEKNKISISDSIKVLTGRLDGFKPKVFNINTKSDVQEAIPYRVMYDKSTFVEE
Sbjct: 1021 DFALLWKIEKNKISISDSIKVLTGRLDGFKPKVFNINTKSDVQEAIPYRVMYDKSTFVEE 1080

Query: 1081 SELTSADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTEFEN 1140
            SELTSADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTEFEN
Sbjct: 1081 SELTSADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTEFEN 1140

Query: 1141 FQKSCDGSQIGPFSLGLNLKEIISQRGTLENSNSPVPEFSHGIGISNADSQSTCDAERGN 1200
            FQKSCDGSQIGPFSLGLNLKEIISQRGTLENSNSPVPEFSHGIGISNADSQSTCDAERGN
Sbjct: 1141 FQKSCDGSQIGPFSLGLNLKEIISQRGTLENSNSPVPEFSHGIGISNADSQSTCDAERGN 1200

Query: 1201 SEQAEMRAVTPENHESMTSIFPSAAVGLKNNNDILPNSQEELLYSSKQSFPGILKATTPK 1260
            SEQAEMRAVTPENHESMTSIFPSAAVGLKNNNDILPNSQEELLYSSKQSFPGILKATTPK
Sbjct: 1201 SEQAEMRAVTPENHESMTSIFPSAAVGLKNNNDILPNSQEELLYSSKQSFPGILKATTPK 1260

Query: 1261 DMSETEKNLVVTETGDNIHSPSHFSDIFNFVSSTSNLELNEEIYFTDSLEIKRNENFPKD 1320
            DMSETEKNLVVTETGDNIHSPSHFSDIFNFVSSTSNLELNEEIYFTDSLEIKRNENFPKD
Sbjct: 1261 DMSETEKNLVVTETGDNIHSPSHFSDIFNFVSSTSNLELNEEIYFTDSLEIKRNENFPKD 1320

Query: 1321 YVKFSDEEEFMNEDEKEMKEILMAGSSLSAGVSGEDKTEILNPTPAMAKSLTIDCLELAL 1380
            YVKFSDEEEFMNEDEKEMKEILMAGSSLSAGVSGEDKTEILNPTPAMAKSLTIDCLELAL
Sbjct: 1321 YVKFSDEEEFMNEDEKEMKEILMAGSSLSAGVSGEDKTEILNPTPAMAKSLTIDCLELAL 1380

Query: 1381 PPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWKESVMERQRQEEVSCGK 1440
            PPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWKESVMERQRQEEVSCGK
Sbjct: 1381 PPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWKESVMERQRQEEVSCGK 1440

Query: 1441 FMQDPSLVGHTGLDNPEQKSSQRTGKKLLKTLTASEMLPLLDHWNTQTKKVSLREIMSEE 1500
            FMQDPSLVGHTGLDNPEQKSSQRTGKKLLKTLTASEMLPLLDHWNTQTKKVSLREIMSEE
Sbjct: 1441 FMQDPSLVGHTGLDNPEQKSSQRTGKKLLKTLTASEMLPLLDHWNTQTKKVSLREIMSEE 1500

Query: 1501 IALQEKHNLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHNYSLEHTVQFLN 1560
            IALQEKHNLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHNYSLEHTVQFLN
Sbjct: 1501 IALQEKHNLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHNYSLEHTVQFLN 1560

Query: 1561 CVLEGDPVKTVVAQEFVHQNENVTSHTGQKSKEKKPKKLKETEETPSELSFQDFEYPDYD 1620
            CVLEGDPVKTVVAQEFVHQNENVTSHTGQKSKEKKPKKLKETEETPSELSFQDFEYPDYD
Sbjct: 1561 CVLEGDPVKTVVAQEFVHQNENVTSHTGQKSKEKKPKKLKETEETPSELSFQDFEYPDYD 1620

Query: 1621 DYRAEAFLHQQKRMECYSKAKEAYRIGKKNVATFYAQQGTLHEQKMKEANHLAAIEIFEK 1680
            DYRAEAFLHQQKRMECYSKAKEAYRIGKKNVATFYAQQGTLHEQKMKEANHLAAIEIFEK
Sbjct: 1621 DYRAEAFLHQQKRMECYSKAKEAYRIGKKNVATFYAQQGTLHEQKMKEANHLAAIEIFEK 1680

Query: 1681 VNASLLPQNVLDLHGLHVDEALEHLMRVLEKKTEEFKQNGGKPYLSVITGRGNHSQGGVA 1740
            VNASLLPQNVLDLHGLHVDEALEHLMRVLEKKTEEFKQNGGKPYLSVITGRGNHSQGGVA
Sbjct: 1681 VNASLLPQNVLDLHGLHVDEALEHLMRVLEKKTEEFKQNGGKPYLSVITGRGNHSQGGVA 1740

Query: 1741 RIKPAVIKYLISHSFRFSEIKPGCLKVMLK 1770
            RIKPAVIKYLISHSFRFSEIKPGCLKVMLK
Sbjct: 1741 RIKPAVIKYLISHSFRFSEIKPGCLKVMLK 1770


>gi|7656971 phosphonoformate immuno-associated protein 5 isoform 2
           [Homo sapiens]
          Length = 583

 Score =  184 bits (466), Expect = 9e-46
 Identities = 84/160 (52%), Positives = 119/160 (74%)

Query: 429 QVVRKKTSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYINGQYQFDVKY 488
           Q   +K + +  +L+LLRGLPGSGK+ L+R L   N  G++ STDDYF+    Y+++V  
Sbjct: 391 QFQEEKLNKLQKLLILLRGLPGSGKTTLSRILLGQNRDGIVFSTDDYFHHQDGYRYNVNQ 450

Query: 489 LGEAHEWNQNRAKEAFEKKISPIIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKF 548
           LG+AH+WNQNRAK+A ++  SP+IIDNTN+QAWEMKPYV ++    Y+V F EP+TWWKF
Sbjct: 451 LGDAHDWNQNRAKQAIDQGRSPVIIDNTNIQAWEMKPYVEVAIGKGYRVEFHEPETWWKF 510

Query: 549 KPKELARRNIHGVSKEKITRMLEHYQRFVSVPIIMSSSVP 588
            P+EL +RN HGVS++KI +ML+ Y+  +S+ I+M+S  P
Sbjct: 511 DPEELEKRNKHGVSRKKIAQMLDRYEYQMSISIVMNSVEP 550


>gi|119226224 NEDD4 binding protein 2-like 1 isoform 1 [Homo
           sapiens]
          Length = 243

 Score =  182 bits (461), Expect = 3e-45
 Identities = 88/153 (57%), Positives = 113/153 (73%), Gaps = 1/153 (0%)

Query: 442 LVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYI-NGQYQFDVKYLGEAHEWNQNRA 500
           L LLRGLPGSGK+ LAR LQ D P  +I STDD+F+  +G Y+F+  +L EAHEWNQ RA
Sbjct: 44  LYLLRGLPGSGKTTLARQLQHDFPRALIFSTDDFFFREDGAYEFNPDFLEEAHEWNQKRA 103

Query: 501 KEAFEKKISPIIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHG 560
           ++A    ISPIIIDNTNL AWEMKPY  ++ ++ Y+V+FREPDT WKF  +ELARRNIHG
Sbjct: 104 RKAMRNGISPIIIDNTNLHAWEMKPYAVMALENNYEVIFREPDTRWKFNVQELARRNIHG 163

Query: 561 VSKEKITRMLEHYQRFVSVPIIMSSSVPEKIER 593
           VS+EKI RM E Y+  V+   ++ +  P ++ R
Sbjct: 164 VSREKIHRMKERYEHDVTFHSVLHAEKPSRMNR 196


>gi|119226227 NEDD4 binding protein 2-like 1 isoform 2 [Homo
           sapiens]
          Length = 173

 Score =  120 bits (301), Expect = 1e-26
 Identities = 62/111 (55%), Positives = 77/111 (69%), Gaps = 1/111 (0%)

Query: 442 LVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYI-NGQYQFDVKYLGEAHEWNQNRA 500
           L LLRGLPGSGK+ LAR LQ D P  +I STDD+F+  +G Y+F+  +L EAHEWNQ RA
Sbjct: 44  LYLLRGLPGSGKTTLARQLQHDFPRALIFSTDDFFFREDGAYEFNPDFLEEAHEWNQKRA 103

Query: 501 KEAFEKKISPIIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPK 551
           ++A    ISPIIIDNTNL AWEMKPY  +  + + K LFR       F+P+
Sbjct: 104 RKAMRNGISPIIIDNTNLHAWEMKPYAVMVFQTEQKNLFRLEMDMVVFRPE 154


>gi|157278100 phosphonoformate immuno-associated protein 5 isoform 1
           [Homo sapiens]
          Length = 752

 Score =  112 bits (279), Expect = 4e-24
 Identities = 73/227 (32%), Positives = 114/227 (50%), Gaps = 23/227 (10%)

Query: 500 AKEAFEKKISPIIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIH 559
           AK+A ++  SP+IIDNTN+QAWEMKPYV ++    Y+V F EP+TWWKF P+EL +RN H
Sbjct: 33  AKQAIDQGRSPVIIDNTNIQAWEMKPYVEVAIGKGYRVEFHEPETWWKFDPEELEKRNKH 92

Query: 560 GVSKEKITRMLEHYQRFVSVPIIMSSSVPEKIERIELCAYSCEDRSTSPRDDEDIISEKE 619
           GVS++KI +ML+ Y+  +S+ I+M+S  P         ++    R   P+        + 
Sbjct: 93  GVSRKKIAQMLDRYEYQMSISIVMNSVEP---------SHKSTQRPPPPQ------GRQR 137

Query: 620 ENILSLSLKHLEFTEEKNLDVTKETMLPENVAYLSNADLNKRRKEISDMNPSIQSALILE 679
           E +L  +   L  T++K      +    +N     N+      + +SD+ P  Q     E
Sbjct: 138 ERVLKKTGHRLSKTKQKRNRKRNKKQNSQNRIMEENS-----LEFLSDLTPGDQDPSQSE 192

Query: 680 TPHMYFSDSESKLQATDKSENEQIEMVA---VKGYSKTDTDSSMERV 723
              +  +  ES+    D  +NE  + V     K +   D   S + V
Sbjct: 193 EEDIEKTRRESEYPFIDGLQNEVGDFVTGYKEKRWKNKDPKDSFQNV 239



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 26/58 (44%), Positives = 36/58 (62%)

Query: 1376 LELALPPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWKESVMERQRQ 1433
            LEL L    AFQL +LFG  G+   SL  +D VV +D    K+I+ +WK SV +RQ++
Sbjct: 693  LELPLSQGFAFQLVKLFGSPGVPMESLLPDDYVVPLDWKTLKMIYLQWKMSVEKRQKK 750


>gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo
           sapiens]
          Length = 421

 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 45/181 (24%), Positives = 84/181 (46%), Gaps = 26/181 (14%)

Query: 403 SHTSPTKVWRNKDGTSA----------YQVQETPVSQVVRKKTSYVGLVLVLLRGLPGSG 452
           SHT   K++  K  +S           +   E  V+ ++  KT      L +LRGLPGSG
Sbjct: 9   SHTFLPKIFFRKMSSSGAKDKPELQFPFLQDEDTVATLLECKT------LFILRGLPGSG 62

Query: 453 KSFLARTLQEDNPSGVILSTDDYFYI----NGQYQFDVKYLGEAHEWNQNRAKEAFEKKI 508
           KS LAR + +    G  + + D + I     G +  + K L E      + A     + I
Sbjct: 63  KSTLARVIVDKYRDGTKMVSADAYKITPGARGAFSEEYKRLDE------DLAAYCRRRDI 116

Query: 509 SPIIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGVSKEKITR 568
             +++D+TN +   ++    ++ +++Y+V+  EP T W+    +L  +N   +S + + +
Sbjct: 117 RILVLDDTNHERERLEQLFEMADQYQYQVVLVEPKTAWRLDCAQLKEKNQWQLSADDLKK 176

Query: 569 M 569
           +
Sbjct: 177 L 177


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 44/207 (21%), Positives = 93/207 (44%), Gaps = 35/207 (16%)

Query: 441  VLVLLRGLPGSGKSFLARTLQE-----DNPSGVILSTDDYFYINGQYQ------------ 483
            ++V++RGLPGSGK+ +A+ +++       P+  +LS DDYF    + +            
Sbjct: 1835 IVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKK 1894

Query: 484  --FDVKYLGEAHEWNQNRAKEAFEKKISP-----IIIDNTNLQAWEMKPYVALSQKHKYK 536
               + +Y  E  E  +    + F+K +       II+D  N +      + + ++   ++
Sbjct: 1895 KVMEYEYEAEMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFE 1954

Query: 537  VLFREPDTWWKFKPKELARRNIHGVSKEKITRMLEHYQRF------VSVPIIMSSSVPEK 590
            V   E         +   +RNIHG   ++I +M +H++        + +  ++  +  E+
Sbjct: 1955 VYLAEMSA----DNQTCGKRNIHGRKLKEINKMADHWETAPRHMMRLDIRSLLQDAAIEE 2010

Query: 591  IERIELCAYSCEDRSTSPRDDEDIISE 617
            +E  +  A + E++    +D E+  SE
Sbjct: 2011 VEMEDFDA-NIEEQKEEKKDAEEEESE 2036



 Score = 35.4 bits (80), Expect = 0.50
 Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 17/146 (11%)

Query: 235  LESNYPEDSLLSSSLNVASDS-IAGCSSLNQKQKELL-----ESECVEAQFSEAPVDLD- 287
            + S++    ++ S  ++ SD  + G   L+Q+Q E++     E + +  Q  +     D 
Sbjct: 1420 MPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDF 1479

Query: 288  ASEPQACLNLPGLDLPGTGGDQKSTRVSDVFLPSEGFN-----FKPHKHPELPTKGKDVS 342
             SEPQ   +LP    P     Q ++    ++ P   +       KP      P+     S
Sbjct: 1480 GSEPQMADHLP----PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARS 1535

Query: 343  YCPVLAPLPLLLPPPPPPPMWNPMIP 368
              PV  P P+ +PPPPPPP   P  P
Sbjct: 1536 SVPVTRP-PVPIPPPPPPPPLPPPPP 1560


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 68/290 (23%), Positives = 107/290 (36%), Gaps = 37/290 (12%)

Query: 91   DTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQNAF 150
            D+  EE   +S   SE Q    E +  E+  EEE +D       D    +D D+ +  A 
Sbjct: 1030 DSGGEEDEKESL--SEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEAS 1087

Query: 151  EKLNSSPDDQ-----VYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLEN 205
            EK     D++     V S   +   +  ++SSEF    SS  +P  S     +     E 
Sbjct: 1088 EKDEGDSDEEETVSIVTSKAEATSSSESSESSEF--ESSSESSPSSSEDEEEVVAREEEE 1145

Query: 206  SGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQK 265
                             E +  + + ++A  S  PED          +       SL  +
Sbjct: 1146 E---------------EEEEEMVAEESMA--SAGPEDFEQDGEEAALAPGAPAVDSLGME 1188

Query: 266  QKELLESECVEAQ-----FSEAPVDLDASEPQACLNLPGLDLPGTGGDQKSTRVSDVFLP 320
            ++  +E+E V  +       E P+ +   EP      P  + PG    Q+   +     P
Sbjct: 1189 EEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPP--EEPGLS--QEGAMLLSPEPP 1244

Query: 321  SEGFNFKPHKHPE-LPTKGKDVS-YCPVLAPLPLLLPPPPPPPMWNPMIP 368
            ++    +P   PE  P    +V    P++ PLPL  P PPP P   P  P
Sbjct: 1245 AKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPP 1294



 Score = 32.7 bits (73), Expect = 3.2
 Identities = 54/249 (21%), Positives = 88/249 (35%), Gaps = 23/249 (9%)

Query: 124 ESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPD 183
           E     +DS ++M L E    L+          PD      +    ++S +     + P 
Sbjct: 493 EKPHDSLDSRIEMLLKEQRTKLL------FLREPDSDTELQMEGSPISSSSSQLSPLAPF 546

Query: 184 SSNMTPIF---STQNMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYP 240
            +N  P F   +  +   +   LE+    +S  PLP      E    +            
Sbjct: 547 GTNSQPGFRGPTPPSSRPSSTGLED----ISPTPLPDSDEDEELDLGLGPRPPPEPGPPD 602

Query: 241 EDSLLSSSLNVASDSIAGCSSLNQKQKELLESECVEAQFSEAPVDLDASEPQACLNLPGL 300
              LLS +  VA D +   +  ++K  E  +S   + + S+  +   A    A    P +
Sbjct: 603 PAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMP-SAPITSADCPKPMV 661

Query: 301 DLPGTGGDQKSTRVSDVFL--PSEGFNFKPHKHPELPTKGKDVSYCPVLAPLPLLLPPPP 358
             PG       + ++      P  GF   P   P  P +       P+  PLP   PPPP
Sbjct: 662 VTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPG----FPMPPPLP---PPPP 714

Query: 359 PPPMWNPMI 367
           PPP  +P +
Sbjct: 715 PPPPAHPAV 723



 Score = 32.3 bits (72), Expect = 4.2
 Identities = 32/102 (31%), Positives = 39/102 (38%), Gaps = 16/102 (15%)

Query: 283 PVDLDASEPQACLNLPGLDLP-------GTGGDQKSTRVSDVFLPSEGFNFKPHKHPELP 335
           P  L +   +  L+L G   P       G     +   +SD  +PS          P + 
Sbjct: 603 PAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVV 662

Query: 336 TKGKDVSYCP-VLAP-LPLL-------LPPPPPPPMWNPMIP 368
           T G      P VLAP LPL        LPPPPPPP   P  P
Sbjct: 663 TPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFP 704


>gi|110349721 titin isoform novex-3 [Homo sapiens]
          Length = 5604

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 86/399 (21%), Positives = 158/399 (39%), Gaps = 41/399 (10%)

Query: 1030 KNKISISDSIKVLTGRLD-GFKPKVFNINTKSDVQEAIPYRVMYDKSTFVEESELTSAD- 1087
            K KI   ++++  T  +    +  VF     S  QE +  R M +KS+  E S     + 
Sbjct: 4646 KEKIPSPETLQPDTHNISKSVQNNVFASQEISSSQE-LSNRTMVEKSSIDENSISLEKEV 4704

Query: 1088 ---ESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTEFENFQKS 1144
               + +NL+IL       SL++  +       +I   +  LL + +   E+T+    +KS
Sbjct: 4705 RHVQEQNLDILKT---DLSLKSFSE-------EIYSESCALLPTSSADIEETDLS--EKS 4752

Query: 1145 CDGSQIGPFSLGLNLKEIISQR-----GTLENSNSPVPE---FSHGIGISNADSQSTCDA 1196
            C     G  S+  +LK+  S+      G +E   +  PE   F    G +   + +T + 
Sbjct: 4753 CPLENGGRSSIS-HLKKAASEEKPLGVGEMEEECTLEPELAAFPKQDGGTQEYTDATLED 4811

Query: 1197 ERGNSEQAEMRAVTPENHESMTSIFPSAAVGLKNN--NDILPN---SQEELLYSSKQSFP 1251
             RG+ ++A+    T     S++  FP      + N    I  N   S EE  Y   Q   
Sbjct: 4812 HRGDVQEAD----TLHRQLSLSQCFPLLMTEEQQNPGEQISTNIHASGEEKCYEEVQVQN 4867

Query: 1252 GILKATTPKDMSETE--KNLVVTETGDNIHSPSHFSDIFNFVSSTSNLELNEEIYFTDSL 1309
                +T   +M ET   +N+   +      +    + +  ++ +    E+ E     D  
Sbjct: 4868 EASFSTLEGEMIETSFSQNIPKLDEAHTTEAAESETSLTQYLLAAGKREVPETKDTRDQA 4927

Query: 1310 EIKRNENFPK---DYVKFSDEEEFMNEDEKEMKEILMAGSSLSAGVSGEDKTEILNPTPA 1366
            ++ ++E+      + V F+   E+ N+ ++ +   L   S +S GV      EI      
Sbjct: 4928 KLVQSESITSMEVEEVTFNTVYEYYNQKQESLGRPLSPESDISIGVGSTTSEEISELDQF 4987

Query: 1367 MAKSLTIDCLELALPPELAFQLNELFGPVGIDSGSLTVE 1405
                 +++  E    P+L F  +++     I SG  TVE
Sbjct: 4988 YTPPSSVEYFESPKSPDLYFNPSDITKQSSIHSGGETVE 5026


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 108/630 (17%), Positives = 219/630 (34%), Gaps = 43/630 (6%)

Query: 686  SDSESKLQATDKSENEQIEMVAVKGYS-KTDTDSSMERVSPSTCCSENNQEDCDLANSGP 744
            SDS     ++D S++   +  + K  S  +D+DS  +    ++  S +N +  D +NS  
Sbjct: 605  SDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS- 663

Query: 745  LQNEKSSPGEIVEERATVTKKAFGKQKSKSTLEKFPRHELSNFVGDWPVDKTIGQRTKRN 804
              N   S        ++ +  +     S  + +     E S+       D +    +  +
Sbjct: 664  --NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721

Query: 805  RKTEKTSSVQSDKKYNYPQSHKLVNSVSVNTDCVQQRGSPHESVEDGRKSQCDDASEPLN 864
              ++  SS  SD   +   S    +S S N+           S +    S   D+S+  N
Sbjct: 722  NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781

Query: 865  SY-KYDAYKNIDKNSFNIMGDWPSSDSLAQREHRSRMPKTGLSEPNLEIGTNDKMNEISL 923
            S    D+  + D +  +   D  +S   +     S    +  S+ +    ++D  N    
Sbjct: 782  SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841

Query: 924  STAHEACWGTSSQKLKTLGSSNLGSSEMLLSEMTCESQTCLSKKSHGQHTSLPLTFTNSA 983
            S + ++  G+ S       SSN   S            +  S  +   ++S     +NS+
Sbjct: 842  SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901

Query: 984  PTVSGVVEPQTLAECQEQMPKRDPGKEVGMCTQTEPQDFALLWKIEKNKISISDSIKVLT 1043
             + S   +    ++  +     D  +       +   D         N    SDS     
Sbjct: 902  DSDSS--DSSNSSDSSDSSNSSDSSESSNSSDNSNSSD-------SSNSSDSSDS----- 947

Query: 1044 GRLDGFKPKVFNINTKSDVQEAIPYRVMYDKSTFVEESELTSADESENLNILCKLFGSFS 1103
                            SD   +       D S   + S+  S+D S++ N       S S
Sbjct: 948  ----------------SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991

Query: 1104 LEALKDLYERCNKDIIWATSLLLDS-----ETKLCEDTEFENFQKSCDGSQIGPFSLGLN 1158
             ++  D  +  N      +S   DS      +   + +   +   S D S     S   +
Sbjct: 992  SDS-SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD 1050

Query: 1159 LKEIISQRGTLENSNSPVPEFSHGIGISNADSQSTCDAERGNSEQAEMRAVTPENHESMT 1218
              +  +   + ++S+S     S     S+  S+S+  ++  NS  +   + + ++ +S  
Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD 1110

Query: 1219 SIFPSAAVGLKNNNDILPNSQEELLYSSKQSFPGILKATTPKDMSETEKNLVVTETGDNI 1278
            S   S +    N++D   +S       S  S      ++   D S++  +   +++ D+ 
Sbjct: 1111 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS-SDSSESSDSSDSSDSSDSSDSSDSS 1169

Query: 1279 HSPSHFSDIFNFVSSTSNLELNEEIYFTDS 1308
             S S  SD  N   S+ + + ++    +DS
Sbjct: 1170 DS-SDSSDSSNSSDSSDSSDSSDSSDSSDS 1198



 Score = 38.5 bits (88), Expect = 0.059
 Identities = 43/203 (21%), Positives = 85/203 (41%), Gaps = 1/203 (0%)

Query: 88  SATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQ 147
           S +D+     SS S  +S++   +  S   +     +S +S   S           S   
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783

Query: 148 NAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENSG 207
           ++ +  NSS      +   S + +  +DSS+  + DSSN +   ++ + + +  + ++S 
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843

Query: 208 STLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQKQK 267
           S+ S +   S S          D++ + +S+   DS  SS  N +S+S     S N    
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS 903

Query: 268 ELLESECVEAQFSEAPVDLDASE 290
           +  +S    +  S++    D+SE
Sbjct: 904 DSSDSS-NSSDSSDSSNSSDSSE 925



 Score = 37.7 bits (86), Expect = 0.100
 Identities = 38/173 (21%), Positives = 76/173 (43%), Gaps = 2/173 (1%)

Query: 88  SATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQ 147
           S+  +   +SS  S   S +   +++S   +    + S+    DS      ++  DS   
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613

Query: 148 NAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENSG 207
           +     + S  D   S   S D +S +DSS+  + DSS+ +    + N + + ++ ++S 
Sbjct: 614 SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSD 673

Query: 208 STLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCS 260
           S+ S +   S +  + S     D++ + ES+   DS  S S + +  S +  S
Sbjct: 674 SSDSSSSSDSSNSSDSSDS--SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS 724



 Score = 37.7 bits (86), Expect = 0.100
 Identities = 41/174 (23%), Positives = 75/174 (43%), Gaps = 7/174 (4%)

Query: 89  ATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQN 148
           ++D+    SSS S  +S++   +  S   E     +S DS      D   +   DS   N
Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730

Query: 149 AFEKL---NSSPDDQVYSFLPSQDVNSFNDSSEFI----NPDSSNMTPIFSTQNMNLNGE 201
           + +     NSS          S D +  +DSS       + DSS+ +   ++ + N +  
Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN 790

Query: 202 NLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDS 255
           + ++S S+ S +   S    + S     D++ + +S+   DS  SS+ + +SDS
Sbjct: 791 SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844



 Score = 37.7 bits (86), Expect = 0.100
 Identities = 44/188 (23%), Positives = 78/188 (41%), Gaps = 3/188 (1%)

Query: 74  DFKVENAMDCLLELSATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSF 133
           D    N+ D     +++D+     SS S  +S++   +  S   +     +S DS   S 
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784

Query: 134 LDMQLTEDLDSLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFST 193
            +        S   N+ +  NSS          S   NS + S+   + DSSN +   S 
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD-SSD 843

Query: 194 QNMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVAS 253
            + + +G + ++S  + S N   S    + S     D++ + +SN   +S  SS  + +S
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS--SDSSDSSDSNESSNSSDSSDSSNSS 901

Query: 254 DSIAGCSS 261
           DS +  SS
Sbjct: 902 DSDSSDSS 909



 Score = 37.7 bits (86), Expect = 0.100
 Identities = 47/230 (20%), Positives = 91/230 (39%), Gaps = 5/230 (2%)

Query: 89  ATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSK--MDSFLDMQLTEDLDSLI 146
           ++D+     SS S  +S++   +  S   +     +S DS    DS      ++  DS  
Sbjct: 758 SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817

Query: 147 QNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENS 206
            ++    +SS          S D +  +DSS+  + DSSN +    + N + + ++ ++S
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRS---DSSNSSDSSDSSDSS 874

Query: 207 GSTLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQKQ 266
            S+ S +   S+   N S      N+   +S+   +S  SS  + +SDS    +S +   
Sbjct: 875 NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934

Query: 267 KELLESECVEAQFSEAPVDLDASEPQACLNLPGLDLPGTGGDQKSTRVSD 316
                +    +  S++    D+S      N        +     S+  SD
Sbjct: 935 SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 48/189 (25%), Positives = 73/189 (38%), Gaps = 18/189 (9%)

Query: 79  NAMDCLLELSATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQL 138
           N+ D     +++D+     SS S  +S++    +          + S  S      D   
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849

Query: 139 TEDLDSLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFIN----PDSSNMTPIFSTQ 194
             D DS   N  +  NSS          S D +  +DS+E  N     DSSN +   S+ 
Sbjct: 850 GSDSDS--SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907

Query: 195 NMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASD 254
           + N       +S S+ S N   S    N S     DN+ + +S+   DS  SS  + +SD
Sbjct: 908 SSN-------SSDSSDSSNSSDSSESSNSS-----DNSNSSDSSNSSDSSDSSDSSNSSD 955

Query: 255 SIAGCSSLN 263
           S     S N
Sbjct: 956 SSNSSDSSN 964



 Score = 35.4 bits (80), Expect = 0.50
 Identities = 41/217 (18%), Positives = 84/217 (38%)

Query: 74   DFKVENAMDCLLELSATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSF 133
            D    N  D      ++D+    +SS S  +S++   +  S   +     +S+ S   + 
Sbjct: 852  DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNS 911

Query: 134  LDMQLTEDLDSLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFST 193
             D   + +     +++    NS+  D   S   S   +S N S    + DSSN +    +
Sbjct: 912  SDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 971

Query: 194  QNMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVAS 253
             + + +  +  +  S  S +   S S  + +     D++ + +S+   DS  SS  + +S
Sbjct: 972  NSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031

Query: 254  DSIAGCSSLNQKQKELLESECVEAQFSEAPVDLDASE 290
            DS     S +             +  S++    D+S+
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068



 Score = 35.4 bits (80), Expect = 0.50
 Identities = 64/365 (17%), Positives = 126/365 (34%), Gaps = 18/365 (4%)

Query: 605  STSPRDDEDIISEKEENILSLSLKHLEFTEEKNLDVTKETMLPENVAYLSNADLNKRRKE 664
            S++  D  D  +  + +  S S  +   ++  N   + ++    N +  SN+  +    +
Sbjct: 908  SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSD 967

Query: 665  ISDMNPSIQSALILETPHMYFSDSESKLQATDKSENEQIEMVAVKGYSKTDTDSSMERVS 724
             SD N S  S            DS +   ++D S++      +    S   +DSS    S
Sbjct: 968  SSDSNSSDSS------------DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015

Query: 725  PSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERATVTKKAFGKQKSKSTLEKFPRHEL 784
             ++  S N+    D +NS    +   S        ++ +  +     S  + +     + 
Sbjct: 1016 SNSSDSSNSS---DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072

Query: 785  SNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDKKYNYPQSHKLVNSVSVNTDCVQQRGSP 844
            S+        ++       N      SS  SD   +   S    +S S N+         
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132

Query: 845  HESVEDGRKSQCDDASEPLNSY-KYDAYKNIDKNSFNIMGDWPSSDSLAQREHRSRMPKT 903
             +S +    S   D+SE  +S    D+  + D +  +   D  SSDS    +       +
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSD--SSDSSNSSDSSDSSDSS 1190

Query: 904  GLSEPNLEIGTNDKMNEISLSTAHEACWGTSSQKLKTLGSSNLGSSEMLLSEMTCESQTC 963
              S+ +    ++D  +    S + ++   + S        SN  S     S+ +  S + 
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS 1250

Query: 964  LSKKS 968
             S  S
Sbjct: 1251 DSSDS 1255



 Score = 35.4 bits (80), Expect = 0.50
 Identities = 44/203 (21%), Positives = 86/203 (42%), Gaps = 10/203 (4%)

Query: 89   ATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQN 148
            ++D+     SS+S  +S+N   +  S   +     +S +S  DS      +   DS   N
Sbjct: 914  SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS-DSSNSSDSSNSSDSSDSN 972

Query: 149  AFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENSGS 208
            + +  +SS          S D +  +DSS+  + DSSN +    + + + +  + ++S S
Sbjct: 973  SSDSSDSSNSSD------SSDSSDSSDSSD--SSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024

Query: 209  TLSLNPLPSHSVLNES-KCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQKQK 267
            + S N   S    + S      D++ + +S+   DS  SS  + +SDS     S +  + 
Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSES 1084

Query: 268  ELLESECVEAQFSEAPVDLDASE 290
                     +  S++    D+S+
Sbjct: 1085 SDSSDSSNSSDSSDSSDSSDSSD 1107



 Score = 35.0 bits (79), Expect = 0.65
 Identities = 73/387 (18%), Positives = 142/387 (36%), Gaps = 25/387 (6%)

Query: 598 AYSCEDRSTSPRDDEDIISEKEENILSLSLKHLEFTEEKNLDVTKETMLPENVAYLSNAD 657
           A S  D ++S R D    S++ ++  + S    +  E+ + D T +T         +N+D
Sbjct: 477 ANSESDNNSSSRGDASYNSDESKDNGNGS--DSKGAEDDDSDSTSDT---------NNSD 525

Query: 658 LNKRRKEISDMNPSIQSAL-ILETPHMYFSDSESKLQATDKSENEQIEMVAVKGYSKTDT 716
            N      +D N    S     ++     SDS +   ++D S+++  +  +      +D+
Sbjct: 526 SNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDS 585

Query: 717 DSSMERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERATVTKKAFGKQKSKSTL 776
           DSS    S S+  S N+ +  D ++S    +   S     +   + +  +    KS S+ 
Sbjct: 586 DSSDSSDSDSSD-SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSD 644

Query: 777 EKFPRHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDKKYNYPQSHKLVNSVSVNTD 836
                   SN         +       N      SS  SD   +   S+   +S S ++ 
Sbjct: 645 --------SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696

Query: 837 CVQQRGSPHESVEDGRKSQCDDASEPLNSYKYDAYKNIDKNSFNIMGDWPSSDSLAQREH 896
                 S      D   S   D+S+  NS   D+  +   +S +      SSDS      
Sbjct: 697 ----NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752

Query: 897 RSRMPKTGLSEPNLEIGTNDKMNEISLSTAHEACWGTSSQKLKTLGSSNLGSSEMLLSEM 956
                 +  S  +    ++D  +    S + ++   ++S       +S+  S+    S+ 
Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812

Query: 957 TCESQTCLSKKSHGQHTSLPLTFTNSA 983
           +  S +  S  S   ++S     +NS+
Sbjct: 813 SDSSDSDSSNSSDSSNSSDSSDSSNSS 839



 Score = 35.0 bits (79), Expect = 0.65
 Identities = 43/204 (21%), Positives = 84/204 (41%), Gaps = 12/204 (5%)

Query: 93  KIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQNAFEK 152
           K +    +S  +  +   ++ S       + +S DS   S  D   ++  DS   ++ + 
Sbjct: 539 KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS 598

Query: 153 LNSSPDDQVYSFLPSQDVNSFNDS------SEFINPDSSNMTPIFSTQNMNLNGENLENS 206
            NSS          S D +  +DS      SE  + DS + +   S  N + + +N ++S
Sbjct: 599 SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD-SSDSNSSDSSDNSDSS 657

Query: 207 GSTLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQKQ 266
            S+ S N   S    + S     D++ + +S+   DS  SS  + +S+S     S +   
Sbjct: 658 DSSNSSNSSDSSDSSDSS-----DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS 712

Query: 267 KELLESECVEAQFSEAPVDLDASE 290
            +  +S    +  S++    D+S+
Sbjct: 713 SDSSDSSNSNSSDSDSSNSSDSSD 736



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 42/202 (20%), Positives = 81/202 (40%), Gaps = 4/202 (1%)

Query: 89   ATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQN 148
            ++D+    +SS S  +S++   +  S   +     +S DS   S  D   + D      +
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS--DSSNSSDSSDSSDS 1066

Query: 149  AFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENSGS 208
            +    +S   D   S   S   +S N S    + DSS+ +    + + + + ++  +S S
Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126

Query: 209  TLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQKQKE 268
            + S +   S    N S     D++ + +S+   DS  SS  + +SDS     S N     
Sbjct: 1127 SDSSDSSDSSDSSNSSDS--SDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184

Query: 269  LLESECVEAQFSEAPVDLDASE 290
                    +  S++    D+S+
Sbjct: 1185 DSSDSSDSSDSSDSSDSSDSSD 1206



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 43/176 (24%), Positives = 75/176 (42%), Gaps = 10/176 (5%)

Query: 88  SATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQ 147
           S +D+K + S S S  +S+N   +  S         +S DS  DS      +   DS   
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS-DSSSSSDSSNSSDS--S 690

Query: 148 NAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENSG 207
           ++ +  NSS          S D +S +DSS+  +  +SN +   S+ + + +  +  +  
Sbjct: 691 DSSDSSNSSESSD------SSD-SSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS 743

Query: 208 STLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLN 263
           S  S +   S S  +       D++ + +S+   DS  SS  N +S+S     S N
Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 53/254 (20%), Positives = 107/254 (42%), Gaps = 19/254 (7%)

Query: 7   NLGGNPFRKTANPKEVVVSSVASREEPTTTLPSMGETKVDQEELFTSISEIFSDLDPDVV 66
           N G +   K+ + K    SS +   + + +  S   +  D  +  +S     SD D    
Sbjct: 531 NNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS-- 588

Query: 67  YLMLSECDFKVENAMDCLLELSATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESE 126
                  D    ++ D      ++D+     SS S  +S+++  +++S+      + +S+
Sbjct: 589 -------DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641

Query: 127 DSKMDSFLDMQLTEDLDSL-IQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINP--- 182
            S  +S      ++  DS    N+ +  +SS      S   S + +  +DSS+  N    
Sbjct: 642 SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701

Query: 183 -DSSNMTPIFSTQNMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYPE 241
            DSS+ +   S+ + + +  N  +S S+ S +   S +  + S     D++ +  S+   
Sbjct: 702 SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS-----DSSDSSNSSDSS 756

Query: 242 DSLLSSSLNVASDS 255
           DS  SS+ + +SDS
Sbjct: 757 DSSDSSNSSDSSDS 770



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 41/207 (19%), Positives = 82/207 (39%), Gaps = 7/207 (3%)

Query: 89   ATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLD----- 143
            ++D+     SS S  ++E+   +  S        + S+ S      D   + D       
Sbjct: 870  SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929

Query: 144  SLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENL 203
            S   N+ +  NSS          S D ++ +DSS   +   SN +    + N + + ++ 
Sbjct: 930  SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989

Query: 204  ENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLN 263
            ++S S+ S +   S    + S     D++ + +S+   DS  SS  + +SDS     S +
Sbjct: 990  DSSDSSDSSDSSNSSDSSDSSDS--SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047

Query: 264  QKQKELLESECVEAQFSEAPVDLDASE 290
                    +    +  S++    D+S+
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSD 1074



 Score = 32.3 bits (72), Expect = 4.2
 Identities = 44/225 (19%), Positives = 90/225 (40%), Gaps = 8/225 (3%)

Query: 74   DFKVENAMDCLLELSATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSF 133
            D    N+ D      ++D+     SS S  +S+     + ++       + S+ S   + 
Sbjct: 817  DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876

Query: 134  LDMQLTEDLD--SLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIF 191
             D   + D +  S   ++ +  NSS  D   S   S   +S N S    + +SS+ +   
Sbjct: 877  SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS 936

Query: 192  STQNMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLAL------ESNYPEDSLL 245
             + N + + ++ ++S S+ S N   S +  + S     D++ +       +S+   DS  
Sbjct: 937  DSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD 996

Query: 246  SSSLNVASDSIAGCSSLNQKQKELLESECVEAQFSEAPVDLDASE 290
            SS  + +SDS     S +        +    +  S++    D+S+
Sbjct: 997  SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041



 Score = 32.0 bits (71), Expect = 5.5
 Identities = 53/315 (16%), Positives = 109/315 (34%), Gaps = 5/315 (1%)

Query: 654  SNADLNKRRKEISDMNPSIQSALILETPHMYFSDSESKLQATDKSENEQIEMVAVKGYSK 713
            S++  +    + SD N S  S+   ++ +   SDS     ++D S++      +    S 
Sbjct: 871  SDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSS 930

Query: 714  TDTDSSMERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERATVTKKAFGKQKSK 773
             +++SS    S  +  S ++    D +NS    N   S      + +  +  +     S 
Sbjct: 931  DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990

Query: 774  STLEKFPRHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDKKYNYPQSHKLVNSVSV 833
            S+ +     + SN         +       +      SS  SD   +   S    +S S 
Sbjct: 991  SS-DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049

Query: 834  NTDCVQQRGSPHESVEDGRKSQCDDASEPLNSYKYDAYKNIDKNSFNIMGDWPSSDSLAQ 893
            ++          +S +    S   D+S+  +S    +  +   +S N      SSDS   
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS----SESSDSSDSSNSSDSSDSSDSSDS 1105

Query: 894  REHRSRMPKTGLSEPNLEIGTNDKMNEISLSTAHEACWGTSSQKLKTLGSSNLGSSEMLL 953
             +       +  S+ +    ++D  +    S +  +   + S +      S+  S     
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165

Query: 954  SEMTCESQTCLSKKS 968
            S+ +  S +  S  S
Sbjct: 1166 SDSSDSSDSSDSSNS 1180



 Score = 31.6 bits (70), Expect = 7.2
 Identities = 39/196 (19%), Positives = 77/196 (39%), Gaps = 2/196 (1%)

Query: 95   EESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLN 154
            E S+S     S N   +  S         +S +S   S           S   N+ +  +
Sbjct: 887  ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946

Query: 155  SSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENSGSTLSLNP 214
            SS          S D ++ +DSS+  + DSS+ +    + + + + ++ ++S S+ S + 
Sbjct: 947  SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1006

Query: 215  LPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQKQKELLESEC 274
              S    + S     D++ + +S+   DS  SS  + +SDS     S +           
Sbjct: 1007 SDSSDSSDSSNS--SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064

Query: 275  VEAQFSEAPVDLDASE 290
              +  S++    D+S+
Sbjct: 1065 DSSDSSDSSDSSDSSD 1080



 Score = 31.2 bits (69), Expect = 9.3
 Identities = 36/184 (19%), Positives = 81/184 (44%), Gaps = 4/184 (2%)

Query: 89  ATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQN 148
           ++D+   +SS+ S  ++ +    + +        + S+ S  DS      +   DS   +
Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS--SD 869

Query: 149 AFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENSGS 208
           + +  NSS          S + +  +DSS   + DSS+ +    + + + + ++ E+S S
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929

Query: 209 TLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQKQKE 268
           + + N   S +  + S     D++ + +S+   DS  SS  + ++ S +  SS +    +
Sbjct: 930 SDNSNSSDSSNSSDSSDS--SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD 987

Query: 269 LLES 272
             +S
Sbjct: 988 SSDS 991


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 38.1 bits (87), Expect = 0.076
 Identities = 46/240 (19%), Positives = 92/240 (38%), Gaps = 24/240 (10%)

Query: 650 VAYLSNADLNKRRKEISDMNPSIQSALILETPHMYFSDSESKLQATDKSENEQIEMVAVK 709
           VAY++   + + R     + P+IQ  L    P       + + + T      + E    +
Sbjct: 8   VAYMNPIAMARWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNE 67

Query: 710 GYSKTDTDSSMERVSPSTCCSENNQE--------DCDLANSGPLQNEKSSPGEIVEERAT 761
            + K + + S E++      S   +E         C  ++S    +  SS  +  +E   
Sbjct: 68  NWKK-ELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDE--- 123

Query: 762 VTKKAFGKQKSKSTLEKFPRHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQS---DKK 818
             +K  GK++ K     +   + S    +    +++ ++ K   +TEK   V+S    +K
Sbjct: 124 --EKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRK 181

Query: 819 YNYPQSHKLVNSVSVNTDCVQQRGSPHESVEDGRKSQCDDASEPLNSYKYDAYKNIDKNS 878
            +YP    L +  S  +D         E V+  +K +C++  +     K    K   K+S
Sbjct: 182 KSYPDDKPLSSESSSESDY-------EEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHS 234



 Score = 35.8 bits (81), Expect = 0.38
 Identities = 45/200 (22%), Positives = 84/200 (42%), Gaps = 29/200 (14%)

Query: 602 EDRSTSPRDDEDIISEKEENILSLSLKHLEFTEEKN------LDVTKETMLPENVAYLSN 655
           +D    PR   + + ++ EN  + S    EF E+ N      L+ ++E +L  N +    
Sbjct: 31  QDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKK 90

Query: 656 ADLNKRRKEISDMNPSIQSALILETPHMYFSDSESK----------------LQATDKSE 699
            +  K+RK+ S  + S  S+    +      D E K                  +T +SE
Sbjct: 91  RERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESE 150

Query: 700 NEQIEMVAVKGYSKTDTDSSMERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEE- 758
           +E  E V  K  SK +T+   +  S S    ++  +D       PL +E SS  +  E+ 
Sbjct: 151 SESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDD------KPLSSESSSESDYEEDV 204

Query: 759 RATVTKKAFGKQKSKSTLEK 778
           +A   ++   ++++K  ++K
Sbjct: 205 QAKKKRRCEEREQAKEKVKK 224


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 37.4 bits (85), Expect = 0.13
 Identities = 66/308 (21%), Positives = 118/308 (38%), Gaps = 55/308 (17%)

Query: 620  ENILSLSLKHLEFTEEKNLDVTKETMLPENVAYLSNADLNKRRKEISDM---NPSIQSAL 676
            E+  SLSL     ++E +LDV+ + + PE++  L   +LN  ++E+  +     +     
Sbjct: 1192 EDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTA 1251

Query: 677  ILETPHMYFSDSESKLQATDKSENEQIEMVAVKGYSKTD-TDSSMERVSPSTCCSENNQE 735
             +  P  + + +      T +              ++TD TD S++R SP++        
Sbjct: 1252 PMSVPEPHAATASPPTDGTTRYS------------AQTDITDDSLDRKSPAS-------- 1291

Query: 736  DCDLANSGPLQNEKSSPGEIV--EERATVTKKAFGKQKSKSTLEKFPRHELSNFVGDWPV 793
                ++S P  N K  PG I   +E       +F K       E  P   L +    W  
Sbjct: 1292 --SFSHSTPSGNGKYLPGAITSPDEHILTPDSSFSKSP-----ESLPGPALEDIAIKWE- 1343

Query: 794  DKTIGQRTKRNRKTEKTSSVQSDKKYNYPQSHKLVNSVSVNTDCVQQRGSPHESVEDGRK 853
            DK  G +       ++TS     KK   P+   L           + +   H+ V + + 
Sbjct: 1344 DKVPGLK-------DRTS---EQKKEPEPKDEVLQQ---------KDKTLEHKEVVEPKD 1384

Query: 854  SQCDDASEPLNSYKYDAYKNIDKNSFNIMGDWPSSDSLAQREHRSRMPK-TGLSEPNLEI 912
            +      E L+  K +A K  DK       D    D+  +++ ++  PK   L E +  +
Sbjct: 1385 TAIYQKDEALH-VKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKAL 1443

Query: 913  GTNDKMNE 920
               DK+ E
Sbjct: 1444 EQKDKIPE 1451


>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
          Length = 2245

 Score = 37.0 bits (84), Expect = 0.17
 Identities = 35/143 (24%), Positives = 56/143 (39%), Gaps = 15/143 (10%)

Query: 184 SSNMTPIFSTQNMNLNGENLENSGSTLSLNPLPSHS-VLNESKCFIKDNTLALESNYPED 242
           +SN T  FS    N   + +  +G   +L P+ S S   N++   I   T + + N    
Sbjct: 645 ASNSTQTFSVTMSNQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPN---- 700

Query: 243 SLLSSSLNVASDSIAGCSSLNQKQKELLESECVEAQFSEAPVDLDASEPQA----CLNLP 298
                  NVA ++    +SLNQ   ++    CV+   S+      A+  Q     C++L 
Sbjct: 701 ------TNVALNTFGALASLNQSISQMAGQSCVQLSISQPANSQTAANSQTTTANCVSLT 754

Query: 299 GLDLPGTGGDQKSTRVSDVFLPS 321
               P    D  +T  S   L S
Sbjct: 755 TTAAPPVTTDSSATLASTYNLVS 777


>gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]
          Length = 809

 Score = 37.0 bits (84), Expect = 0.17
 Identities = 17/36 (47%), Positives = 19/36 (52%), Gaps = 2/36 (5%)

Query: 328 PHKH--PELPTKGKDVSYCPVLAPLPLLLPPPPPPP 361
           PH H  P  P   +    CP+  P P  LPPPPPPP
Sbjct: 53  PHHHLPPPPPPSPQPQPQCPLQPPPPPPLPPPPPPP 88


>gi|21071077 dishevelled-associated activator of morphogenesis 1
           [Homo sapiens]
          Length = 1078

 Score = 37.0 bits (84), Expect = 0.17
 Identities = 37/111 (33%), Positives = 43/111 (38%), Gaps = 18/111 (16%)

Query: 265 KQKELLESECVE-AQFSEAPVDLDA-----SEPQACLNLPGLDLPGTGGDQKSTRVSDVF 318
           K KE LE E  E  Q  +   DL A     S    C ++PG   PG  G    + V    
Sbjct: 489 KMKEKLEKETTEHKQVKQQVADLTAQLHELSRRAVCASIPGGPSPGAPGGPFPSSVPGSL 548

Query: 319 LPSEGFNFKPHKHPELPTKGKDVSYCPVLAPLPLLLPPPPP-PPMWNPMIP 368
           LP       P   P LP         P   PLP   PPPPP PP    ++P
Sbjct: 549 LP-------PPPPPPLPGG----MLPPPPPPLPPGGPPPPPGPPPLGAIMP 588


>gi|4507691 transformation/transcription domain-associated protein
           [Homo sapiens]
          Length = 3830

 Score = 36.6 bits (83), Expect = 0.22
 Identities = 17/38 (44%), Positives = 20/38 (52%)

Query: 332 PELPTKGKDVSYCPVLAPLPLLLPPPPPPPMWNPMIPA 369
           P +PT        P  AP+P   PPPPPPP   P+ PA
Sbjct: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPA 522


>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
           sapiens]
          Length = 1710

 Score = 36.6 bits (83), Expect = 0.22
 Identities = 44/178 (24%), Positives = 75/178 (42%), Gaps = 28/178 (15%)

Query: 714 TDTDSSMERVSPSTCCSENNQEDCDLANSGPLQNE---KSSPGEIVEERATVTKKAFGKQ 770
           +D+DS  E  S S   S+ ++E+   A    +      KSSP  +  +R+ + KK   +Q
Sbjct: 50  SDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQ 109

Query: 771 KSKSTLEKFPRHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDKKYNYPQSHKLVNS 830
           + +       +H+ S+  G         +    + +    SS +  +K +  +  ++  S
Sbjct: 110 QQQ-------QHQASSNSGS--------EEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGS 154

Query: 831 VSVNTDCVQQRGSPHESVEDGRKSQCDDAS---EPLNSYKYDAYKN--IDKNSFNIMG 883
            S +     Q GS  ES E+  KS CD+     EP N  K    +N    KN   I+G
Sbjct: 155 GSPS-----QSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILG 207


>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
           protein [Homo sapiens]
          Length = 1463

 Score = 36.2 bits (82), Expect = 0.29
 Identities = 57/264 (21%), Positives = 100/264 (37%), Gaps = 39/264 (14%)

Query: 45  VDQEELFTSISEIFSDLDPDVVYLMLSECDFKVENAMDCLLELSATDTKIEESSSQSFVA 104
           + Q E+ T +  +   L  D    + SE   KV   + C   LS     +E   ++  + 
Sbjct: 532 LSQSEVKTDVCTVH--LPNDFPTCLTSES--KVYQPVSC--PLSDLSENVESVVNEEKIT 585

Query: 105 SENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDDQVYSF 164
             + V   E K    + EE  E  K++S            +IQ    +   SP+ Q+   
Sbjct: 586 ESSLVEITEHKDFTLKTEELIESPKLES--------SEGEIIQTVDRQSVKSPEVQLLGH 637

Query: 165 LPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNG-------ENLENSGSTLSLNP--- 214
           + ++DV        F N D +N+    S  N+  N        ++LE    +L+ +P   
Sbjct: 638 VETEDVEIIATCDTFGNEDFNNIQD--SENNLLKNNLLNTKLEKSLEEKNESLTEHPRST 695

Query: 215 -LPSHSVLNESKCFIKDNTLAL-----------ESNYPEDSLLSSSLNVASDSIAGCSSL 262
            LP   +    K F +DN   +             +  E S+ +    +  +S+  CS  
Sbjct: 696 ELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSEN 755

Query: 263 NQKQKELLESEC-VEAQFSEAPVD 285
           N    +L + +    +Q SE+P D
Sbjct: 756 NMPSSDLADEKVETVSQPSESPKD 779



 Score = 32.0 bits (71), Expect = 5.5
 Identities = 65/284 (22%), Positives = 105/284 (36%), Gaps = 65/284 (22%)

Query: 592 ERIELCAYSCEDRSTSPRDDEDIISEKEENILS---LSLKHLEFTEEKNLDVTKETMLPE 648
           E +E+ A +C+   T   +D + I + E N+L    L+ K  +  EEKN  +T+     E
Sbjct: 641 EDVEIIA-TCD---TFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTE 696

Query: 649 NVAYLSNADLNKRRKEISDMNPSIQSALILETPHMYFSDSESKLQATDKSENEQIEMVAV 708
               L    + + +K  S+ N  +   + +E        +ES+++ +  ++ +Q+   +V
Sbjct: 697 ----LPKTHIEQIQKHFSEDNNEM---IPMECDSFCSDQNESEVEPSVNADLKQMNENSV 749

Query: 709 KGYSKTDTDSSMERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERATVTKKAFG 768
                             T CSENN    DLA+        S P E  ++    TKK   
Sbjct: 750 ------------------THCSENNMPSSDLADE--KVETVSQPSESPKDTIDKTKK--- 786

Query: 769 KQKSKSTLEKFPRHELSNFVG---DWPVDKTIGQRTKR------NRKTEKTS--SVQSDK 817
                      PR   S F      W  +K   Q  KR       R+T K S  S     
Sbjct: 787 -----------PRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSP 835

Query: 818 KYNYPQSHKLVNSVSVNTDCV------QQRGSPHESVEDGRKSQ 855
           K    +  K   S S   D        Q R    ++  + R+S+
Sbjct: 836 KNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSE 879


>gi|197245373 proline rich 22 isoform 1 [Homo sapiens]
          Length = 422

 Score = 35.8 bits (81), Expect = 0.38
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 288 ASEPQACL-NLPGLDLPGTGGDQKSTRVSDVFLPSEGFNFKPHKHPELPTKGKDVSYCPV 346
           ASEP+  L  +PG  LP + G   +  +  + LP E  +F  +  PE+     +V Y   
Sbjct: 299 ASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSF-DYSVPEILDTVSNVDYFFN 357

Query: 347 LAPLPLLLPPPPPPPMWNPMIP 368
              L    PP P PP  N   P
Sbjct: 358 FKALDEEQPPHPGPPATNTPAP 379


>gi|23503299 proline rich 22 isoform 2 [Homo sapiens]
          Length = 420

 Score = 35.8 bits (81), Expect = 0.38
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 288 ASEPQACL-NLPGLDLPGTGGDQKSTRVSDVFLPSEGFNFKPHKHPELPTKGKDVSYCPV 346
           ASEP+  L  +PG  LP + G   +  +  + LP E  +F  +  PE+     +V Y   
Sbjct: 297 ASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSF-DYSVPEILDTVSNVDYFFN 355

Query: 347 LAPLPLLLPPPPPPPMWNPMIP 368
              L    PP P PP  N   P
Sbjct: 356 FKALDEEQPPHPGPPATNTPAP 377


>gi|221316699 maltase-glucoamylase [Homo sapiens]
          Length = 1857

 Score = 35.8 bits (81), Expect = 0.38
 Identities = 39/158 (24%), Positives = 64/158 (40%), Gaps = 39/158 (24%)

Query: 25  SSVASREEPTTTLPSMGETKVDQEELFTSISEIFSDLDPDVVYLMLSECDFKVENAMDCL 84
           +++ASR+ P   + ++ E K  + ELF    E   D   + VYL+   C+F V       
Sbjct: 829 TTLASRKNPLGLIIALDENKEAKGELFWDNGET-KDTVANKVYLL---CEFSV------- 877

Query: 85  LELSATDTKIEESSSQSFVASENQVGAAESKIMEKR------------PEEESEDSKMDS 132
                T  ++E + SQS     N +   E KI+               P + S     DS
Sbjct: 878 -----TQNRLEVNISQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDS 932

Query: 133 FLDMQLTEDLDSLIQNAF-----------EKLNSSPDD 159
            L + +  D+D L+  A+           EK++  PD+
Sbjct: 933 NLKVAIITDIDLLLGEAYTVEWSIKIRDEEKIDCYPDE 970


>gi|45238858 WD repeat domain 44 protein [Homo sapiens]
          Length = 913

 Score = 35.8 bits (81), Expect = 0.38
 Identities = 59/269 (21%), Positives = 94/269 (34%), Gaps = 40/269 (14%)

Query: 103 VASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDDQVY 162
           V S  +VG +  K  E    +   +S +         + ++S+I+ + +K+    DD + 
Sbjct: 25  VGSPGKVGLSTFKETENTAYKVGNESPVQELKQDVSKKIIESIIEES-QKVLQLEDDSL- 82

Query: 163 SFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENSGSTLSLNP-LPSHSVL 221
                       DS      D +  +PI +  +       L N    L+++  LP  S  
Sbjct: 83  ------------DSKGKELSDQATASPIVARTD-------LSNIPGLLAIDQVLPEESQK 123

Query: 222 NESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQKQKELLESECVEAQFSE 281
            ES+   ++  L L+  +P D      ++  +  +   SS  Q      E+E +  +  E
Sbjct: 124 AESQNTFEETELELKKCFPSDETCEKPVDETT-KLTQTSSTEQLNVLETETEVLNKEAVE 182

Query: 282 APVDLDASEPQACLNLPGLDLPGTGGDQKSTRVSDVFLPSEGFNFKPHKH--PELPTKGK 339
                D  EP                D  ST+  D     E    KP +H  PE      
Sbjct: 183 VKGGGDVLEP-------------VSSDSLSTK--DFAAVEEVAPAKPPRHLTPEPDIVAS 227

Query: 340 DVSYCPVLAPLPLLLPPPPPPPMWNPMIP 368
                P   P P   PPP PPP   P  P
Sbjct: 228 TKKPVPARPPPPTNFPPPRPPPPSRPAPP 256


>gi|120952764 mastermind-like domain containing 1 [Homo sapiens]
          Length = 774

 Score = 35.4 bits (80), Expect = 0.50
 Identities = 56/225 (24%), Positives = 90/225 (40%), Gaps = 34/225 (15%)

Query: 150 FEKLNSSP--DDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENSG 207
           +EK+NS P  D ++   L  +++    D S    P+  ++  I  T+        L++  
Sbjct: 163 YEKINSVPAVDQELQELL--EELTKIQDPS----PNELDLEKILGTKPEE--PLVLDHPQ 214

Query: 208 STLSLNPLPSHSVLN-ESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQKQ 266
           +TLS  P PS  + + ES    K+   +         +   SL + S S     S+    
Sbjct: 215 ATLSTTPKPSVQMSHLESLASSKEFASSCSQ------VTGMSLQIPSSSTGISYSIPSTS 268

Query: 267 KELLESECVEAQFSEAPVDLDASEPQACLN--LPGLDLPGTGGDQKSTRVSDVFLPSEGF 324
           K+++      AQ          S+ QA L   LP L +P       + ++  +    +G 
Sbjct: 269 KQIVSPSSSMAQ--------SKSQVQAMLPVALPPLPVPQW---HHAHQLKALAASKQGS 317

Query: 325 NFKPH----KHPELPTKGKDVSYCPVLAPLPLLLPPPPPPPMWNP 365
             K          LP  G    Y PV +P P  LP PPPPP ++P
Sbjct: 318 ATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPFSP 362


>gi|33356179 transcription termination factor, RNA polymerase I
           [Homo sapiens]
          Length = 905

 Score = 35.0 bits (79), Expect = 0.65
 Identities = 75/358 (20%), Positives = 131/358 (36%), Gaps = 69/358 (19%)

Query: 625 LSLKHLEFT---EEKNLDVTKETMLPENVAYLS---------NADLNKRRKEISDMNPSI 672
           L+ KH++     E  N +   ET     + YLS         +ADL    K++ +  P+I
Sbjct: 446 LASKHVQEAPRLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGSAVKQLQEFIPNI 505

Query: 673 QSALILETPHMYFSDSES-----------KLQATDKSENEQIE-----MVAVKGYSKTD- 715
           +         MY  D E            K       EN+Q+E      +A+ G    D 
Sbjct: 506 KDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKENKQLEKNVEDFLALTGIESADK 565

Query: 716 ---TDSSMERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERATVTKKAFGKQKS 772
              TD   E  S  T           +  +       + P +++  RA   KK F     
Sbjct: 566 LLYTDRYPEEKSVITNLKRRYSFRLHIGRN------IARPWKLIYYRA---KKMFDVNNY 616

Query: 773 KSTLEKFPRHEL----SNFVGDWPVDKTIGQRTKRNR-----KTEKTSSVQSDKKYNYPQ 823
           K    +    +L    S    DW   KTIG+   R+      K  + SS ++   ++  +
Sbjct: 617 KGRYSEGDTEKLKMYHSLLGNDW---KTIGEMVARSSLSVALKFSQISSQRNRGAWSKSE 673

Query: 824 SHKLVNSVSVNTDCVQQRGSPHESVEDGRKSQCDDASEPLNSYKYDAYKNID-------- 875
           + KL+ +V    + + ++ SP E  E   K Q ++    L+  +   YK I         
Sbjct: 674 TRKLIKAVE---EVILKKMSPQELKEVDSKLQ-ENPESCLSIVREKLYKGISWVEVEAKV 729

Query: 876 --KNSFNIMGDWPSSDSLAQREHRSRMPKTGLSEPNLEIGTNDKMNEISLSTAHEACW 931
             +N       W  ++ L +R    R    G++    ++   +++ EI++   +E  W
Sbjct: 730 QTRNWMQCKSKW--TEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDTNEIDW 785


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 35.0 bits (79), Expect = 0.65
 Identities = 16/38 (42%), Positives = 19/38 (50%)

Query: 349 PLPLLLPPPPPPPMWNPMIPAFDLFQGNHGFVAPVVTT 386
           P PLLL PPPPP M  P  P  +     H   +P + T
Sbjct: 173 PPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPT 210



 Score = 32.3 bits (72), Expect = 4.2
 Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 8/67 (11%)

Query: 328 PH--KHPELPTKGKDVSYCPVLAPLPLLLPPPPPPPMWNPMIPAFDLFQGNHGFVAPVVT 385
           PH    P +PT      + P   PL  L PPPPP P   P  PA     G   F    VT
Sbjct: 200 PHTLSSPSIPTPP---DFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256

Query: 386 TAAHWRS 392
               W+S
Sbjct: 257 ---KWKS 260


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 35.0 bits (79), Expect = 0.65
 Identities = 16/38 (42%), Positives = 19/38 (50%)

Query: 349 PLPLLLPPPPPPPMWNPMIPAFDLFQGNHGFVAPVVTT 386
           P PLLL PPPPP M  P  P  +     H   +P + T
Sbjct: 173 PPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPT 210



 Score = 32.3 bits (72), Expect = 4.2
 Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 8/67 (11%)

Query: 328 PH--KHPELPTKGKDVSYCPVLAPLPLLLPPPPPPPMWNPMIPAFDLFQGNHGFVAPVVT 385
           PH    P +PT      + P   PL  L PPPPP P   P  PA     G   F    VT
Sbjct: 200 PHTLSSPSIPTPP---DFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256

Query: 386 TAAHWRS 392
               W+S
Sbjct: 257 ---KWKS 260


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 35.0 bits (79), Expect = 0.65
 Identities = 16/38 (42%), Positives = 19/38 (50%)

Query: 349 PLPLLLPPPPPPPMWNPMIPAFDLFQGNHGFVAPVVTT 386
           P PLLL PPPPP M  P  P  +     H   +P + T
Sbjct: 173 PPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPT 210



 Score = 32.3 bits (72), Expect = 4.2
 Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 8/67 (11%)

Query: 328 PH--KHPELPTKGKDVSYCPVLAPLPLLLPPPPPPPMWNPMIPAFDLFQGNHGFVAPVVT 385
           PH    P +PT      + P   PL  L PPPPP P   P  PA     G   F    VT
Sbjct: 200 PHTLSSPSIPTPP---DFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256

Query: 386 TAAHWRS 392
               W+S
Sbjct: 257 ---KWKS 260


>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
          Length = 444

 Score = 35.0 bits (79), Expect = 0.65
 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 10/82 (12%)

Query: 433 KKTSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYINGQYQFDVKYLGEA 492
           K+T + G   +LL G PG+GKS+LA+ +  +  +    S      ++       K+LGE+
Sbjct: 163 KRTPWRG---ILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVS-------KWLGES 212

Query: 493 HEWNQNRAKEAFEKKISPIIID 514
            +  +N  + A E K S I ID
Sbjct: 213 EKLVKNLFQLARENKPSIIFID 234


>gi|195947369 junction-mediating and regulatory protein [Homo
           sapiens]
          Length = 988

 Score = 35.0 bits (79), Expect = 0.65
 Identities = 33/116 (28%), Positives = 45/116 (38%), Gaps = 17/116 (14%)

Query: 259 CSSL-NQKQKELLESECVEAQFSEAPVDLDASEPQACLNLPGLDLPGTGGDQKSTRVSDV 317
           C SL +  Q E    E  E +    P     +EPQ+ + L          D   T++   
Sbjct: 721 CDSLPSVLQVEEKTEEVGEGRVKRGPSQ--TTEPQSLVQLE---------DTSLTQLEAT 769

Query: 318 FLPSEGFNFKPHKHPELPTKGKDVSYC-----PVLAPLPLLLPPPPPPPMWNPMIP 368
            LP  G   +      LP    ++  C     P+ +PLP   PPPPPPP   P  P
Sbjct: 770 SLPLSGVTSELPPTISLPLLNNNLEPCSVTINPLPSPLPPTPPPPPPPPPPPPPPP 825


>gi|39777606 Rho guanine nucleotide exchange factor 1 isoform 1
           [Homo sapiens]
          Length = 927

 Score = 35.0 bits (79), Expect = 0.65
 Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 16/90 (17%)

Query: 574 QRFVSVPIIMSS-----SVPEKIERIELCAYSCEDR----STSPRDDEDIISEKEENILS 624
           QR    P+++ S       P + E++EL A  C +     + + RD ED++  K+     
Sbjct: 578 QRLTKYPLLLQSIGQNTEEPTEREKVELAAECCREILHHVNQAVRDMEDLLRLKDYQ-RR 636

Query: 625 LSLKHLE------FTEEKNLDVTKETMLPE 648
           L L HL        +E KNLD+TK+ ++ E
Sbjct: 637 LDLSHLRQSSDPMLSEFKNLDITKKKLVHE 666


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,111,026
Number of Sequences: 37866
Number of extensions: 3357874
Number of successful extensions: 15097
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 160
Number of HSP's that attempted gapping in prelim test: 13992
Number of HSP's gapped (non-prelim): 870
length of query: 1770
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1653
effective length of database: 13,817,196
effective search space: 22839824988
effective search space used: 22839824988
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.