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Search of human proteins with 31657094
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31657094 anillin, actin binding protein [Homo sapiens]
(1124 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31657094 anillin, actin binding protein [Homo sapiens] 2208 0.0
gi|26190614 rhotekin 2 [Homo sapiens] 67 7e-11
gi|46048234 nucleolar protein 8 [Homo sapiens] 54 6e-07
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 52 2e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 51 7e-06
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 50 1e-05
gi|110349763 cytohesin 1 isoform 2 [Homo sapiens] 49 2e-05
gi|4758964 cytohesin 1 isoform 1 [Homo sapiens] 49 2e-05
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 49 3e-05
gi|195972859 cytohesin 2 isoform 2 [Homo sapiens] 48 5e-05
gi|8670546 cytohesin 2 isoform 1 [Homo sapiens] 48 5e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 48 6e-05
gi|239047795 pleckstrin homology domain containing, family A mem... 47 8e-05
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 47 8e-05
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 47 8e-05
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 47 8e-05
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 47 8e-05
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 47 8e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 45 4e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 45 4e-04
gi|4758968 cytohesin 3 [Homo sapiens] 45 4e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 45 5e-04
gi|56549111 optineurin [Homo sapiens] 44 7e-04
gi|56549109 optineurin [Homo sapiens] 44 7e-04
gi|20149572 optineurin [Homo sapiens] 44 7e-04
gi|56549107 optineurin [Homo sapiens] 44 7e-04
gi|91982772 mucin 17 [Homo sapiens] 44 7e-04
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap... 44 7e-04
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 43 0.001
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 43 0.002
>gi|31657094 anillin, actin binding protein [Homo sapiens]
Length = 1124
Score = 2208 bits (5722), Expect = 0.0
Identities = 1124/1124 (100%), Positives = 1124/1124 (100%)
Query: 1 MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKS 60
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKS
Sbjct: 1 MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKS 60
Query: 61 CTKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQPQAADTISDSVAVP 120
CTKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQPQAADTISDSVAVP
Sbjct: 61 CTKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQPQAADTISDSVAVP 120
Query: 121 ASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKA 180
ASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKA
Sbjct: 121 ASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKA 180
Query: 181 ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSS 240
ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSS
Sbjct: 181 ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSS 240
Query: 241 ASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKST 300
ASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKST
Sbjct: 241 ASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKST 300
Query: 301 TSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD 360
TSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD
Sbjct: 301 TSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD 360
Query: 361 KSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSST 420
KSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSST
Sbjct: 361 KSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSST 420
Query: 421 THLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGV 480
THLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGV
Sbjct: 421 THLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGV 480
Query: 481 SKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKV 540
SKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKV
Sbjct: 481 SKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKV 540
Query: 541 EQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQED 600
EQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQED
Sbjct: 541 EQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQED 600
Query: 601 ALNISSMSLLAPLAQTVGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAESGD 660
ALNISSMSLLAPLAQTVGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAESGD
Sbjct: 601 ALNISSMSLLAPLAQTVGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAESGD 660
Query: 661 SLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAFPCQVNIKQKM 720
SLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAFPCQVNIKQKM
Sbjct: 661 SLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAFPCQVNIKQKM 720
Query: 721 QELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKRTLLIDELNKL 780
QELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKRTLLIDELNKL
Sbjct: 721 QELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKRTLLIDELNKL 780
Query: 781 KNEGPQRKNKASPQSEFMPSKGSVTLSEIRLPLKADFVCSTVQKPDAANYYYLIILKAGA 840
KNEGPQRKNKASPQSEFMPSKGSVTLSEIRLPLKADFVCSTVQKPDAANYYYLIILKAGA
Sbjct: 781 KNEGPQRKNKASPQSEFMPSKGSVTLSEIRLPLKADFVCSTVQKPDAANYYYLIILKAGA 840
Query: 841 ENMVATPLASTSNSLNGDALTFTTTFTLQDVSNDFEINIEVYSLVQKKDPSGLDKKKKTS 900
ENMVATPLASTSNSLNGDALTFTTTFTLQDVSNDFEINIEVYSLVQKKDPSGLDKKKKTS
Sbjct: 841 ENMVATPLASTSNSLNGDALTFTTTFTLQDVSNDFEINIEVYSLVQKKDPSGLDKKKKTS 900
Query: 901 KSKAITPKRLLTSITTKSNIHSSVMASPGGLSAVRTSNFALVGSYTLSLSSVGNTKFVLD 960
KSKAITPKRLLTSITTKSNIHSSVMASPGGLSAVRTSNFALVGSYTLSLSSVGNTKFVLD
Sbjct: 901 KSKAITPKRLLTSITTKSNIHSSVMASPGGLSAVRTSNFALVGSYTLSLSSVGNTKFVLD 960
Query: 961 KVPFLSSLEGHIYLKIKCQVNSSVEERGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYP 1020
KVPFLSSLEGHIYLKIKCQVNSSVEERGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYP
Sbjct: 961 KVPFLSSLEGHIYLKIKCQVNSSVEERGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYP 1020
Query: 1021 DDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITVRPQREDDRETLVSQCRDTL 1080
DDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITVRPQREDDRETLVSQCRDTL
Sbjct: 1021 DDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITVRPQREDDRETLVSQCRDTL 1080
Query: 1081 CVTKNWLSADTKEERDLWMQKLNQVLVDIRLWQPDACYKPIGKP 1124
CVTKNWLSADTKEERDLWMQKLNQVLVDIRLWQPDACYKPIGKP
Sbjct: 1081 CVTKNWLSADTKEERDLWMQKLNQVLVDIRLWQPDACYKPIGKP 1124
>gi|26190614 rhotekin 2 [Homo sapiens]
Length = 609
Score = 67.4 bits (163), Expect = 7e-11
Identities = 84/372 (22%), Positives = 152/372 (40%), Gaps = 43/372 (11%)
Query: 759 AERLLLIATGKRTLLIDELNKLKNEGPQRKNKASPQ---SEFMPSKGSVTLSEIRLPLKA 815
A + L++ + EL KL+ + + + + E KG + +S+IR+PL
Sbjct: 54 AVKNLMVCNARLMAYTSELQKLEEQIANQTGRCDVKFESKERTACKGKIAISDIRIPLMW 113
Query: 816 DFVCSTVQKPDAANYYYLIILKAGAENMVATPLASTSNSLNGDALTFTTTFTLQDVSNDF 875
K + Y + K GA N+ T + + ++ T F + DF
Sbjct: 114 KDSDHFSNKERSRRYAIFCLFKMGA-NVFDTDVVNVDKTITDICFENVTIFN--EAGPDF 170
Query: 876 EINIEVYSLVQKKD-----PSGLDKKKKTSKSKAITPKRLLTSITTKSNIHSSVMASPGG 930
+I +EVYS ++ P L KK KTS SKA K ++S+ + + ++ S
Sbjct: 171 QIKVEVYSCCTEESSITNTPKKLAKKLKTSISKATGKK--ISSVLQEEDDEMCLLLS--- 225
Query: 931 LSAVRTSNFALVGSYTLSLSSVGNTKFVL-------DKVPFLSSLEGHIYLKIKCQVNSS 983
SAV + L+ TL+L S ++ ++ F L G++ ++ Q
Sbjct: 226 -SAVFGVKYNLLAHTTLTLESAEDSFKTHNLSINGNEESSFWLPLYGNMCCRLVAQPACM 284
Query: 984 VEER--GFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQ 1041
E+ GFL + V G +W R +CVL G + + P++ + K + N +R
Sbjct: 285 AEDAFAGFLNQQQMVEGLISWRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETR- 343
Query: 1042 IEPANREFCARRNTFELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQK 1101
I +++ R + F +I P + ++Q + D +E+ WM+
Sbjct: 344 IRAMDKDAKKRIHNFSVINPVPGQ------AITQI----------FAVDNREDLQKWMEA 387
Query: 1102 LNQVLVDIRLWQ 1113
Q D+ W+
Sbjct: 388 FWQHFFDLSQWK 399
>gi|46048234 nucleolar protein 8 [Homo sapiens]
Length = 1167
Score = 54.3 bits (129), Expect = 6e-07
Identities = 141/667 (21%), Positives = 247/667 (37%), Gaps = 92/667 (13%)
Query: 58 EKSCTKPSPSKKRCSDNTEVEVSNLENKQPVEST------SAKSCSPSPVSPQVQPQAAD 111
EKS K S + + ++ + + K VES S SPS S +A
Sbjct: 404 EKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSPSHSSSSEDADSAS 463
Query: 112 TISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLF 171
++DS M+ L R+ T A +++LA + N+D D PE++
Sbjct: 464 ELADSEGGEEYNAMMKNCL--RVNLTLAD-----LEQLAGSDLKVPNEDTKSDGPETTTQ 516
Query: 172 SPMPSEEKAASPPRPLLSNASATPVGRRGRL----ANLAATICSWEDDV-NHSFAKQNSV 226
K+ P L RRGR A + A++ E++ K+N++
Sbjct: 517 CKFDRGSKSPKTPTGL----------RRGRQCIRPAEIVASLLEGEENTCGKQKPKENNL 566
Query: 227 QEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNAS 286
+ KF + G S+K+ S +D AS NK +S + + +
Sbjct: 567 KP--------KFQAFKGVGCLYEKESMKK-----SLKDSVASNNKDQNSMKHEDPSIISM 613
Query: 287 ISSSVKATSPVKSTTSITDAKSCEGQN---PELLPKTPISPLKTGVS----KPIVKSTLS 339
S + T AK G N P+ T S + VS + K+ +S
Sbjct: 614 EDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPIS 673
Query: 340 QTVPSKGELSREICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTP- 398
+ + K LS + DK + T E QE +S ++ ++P
Sbjct: 674 RPLEGKKSLSLSAKTHNIGFDKDSCHSTTKT--------EASQEERSDSSGLTSLKKSPK 725
Query: 399 IITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKS 458
+ + +T+ I+ ++SS + ++ +K LA L R K+
Sbjct: 726 VSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEAR--------------QKA 771
Query: 459 KQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSS 518
K+++ K+ H L H T + ++ E + +ST+ + E K S
Sbjct: 772 KEVQ-KKLVHNALANLDGHPEDKPTHIIFGSDSECETE----ETSTQEQSHPGEEWVKES 826
Query: 519 PLKIT--LFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEG 576
K + LF D + D KI+ E D+ S +D F
Sbjct: 827 MGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFL 886
Query: 577 ELDMEKSQEEMDQALA----ESSEEQEDALNISSMSLLAPLAQTV--GVVSPESLVS--- 627
E D E+ QEE+++ E +EE++ ALN+ L L+ + G V+ +
Sbjct: 887 ETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIH 946
Query: 628 ---TPRLELKDTSRSDESPKPGKFQRTRVPRAESGDSLGSEDRDLLYSIDAYRSQRFKET 684
T + + D+ PK K +R + + E + L +++ Y+I + F+ T
Sbjct: 947 YDPTKQDHATYERKRDDKPKESKAKRKK--KREEAEKLPEVSKEMYYNIAMDLKEIFQTT 1004
Query: 685 ERPSIKQ 691
+ S K+
Sbjct: 1005 KYTSEKE 1011
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 52.4 bits (124), Expect = 2e-06
Identities = 146/678 (21%), Positives = 236/678 (34%), Gaps = 80/678 (11%)
Query: 101 VSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAE------QRR 154
VSP+ P T+ D + LG L S E++ + T K A+ RR
Sbjct: 196 VSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRR 255
Query: 155 RWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASAT----PV-GRRGRLANLAATI 209
+ D P + S EKA S + +SN + P+ G A
Sbjct: 256 K-------DSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKA 308
Query: 210 CSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASL 269
S E D + A + +Q GT K SAR K + R
Sbjct: 309 TSDEKDSVSNIATEIKKGQQSGTVSPQK------QSARKVIFKKKVSLLNIATRIMGGGK 362
Query: 270 NKALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGV 329
+ +SS AS ++S K S + T I D C + + P LK
Sbjct: 363 SGTVSSQKQPASK-----ATSDKTDSALNIATEIKDGLQCGTVSSQKQPA-----LKATT 412
Query: 330 SKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGGTGIKPFLERF--GERCQEHSKE 387
+ S ++ + GE S + Q Q K+TT + GE+ S +
Sbjct: 413 DEEDSVSNIATEIKD-GEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQ 471
Query: 388 SPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNI 447
P T T + + + +++ + K+ K + + F NI
Sbjct: 472 KPPALTA------TSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFS--NI 523
Query: 448 WSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPK 507
+K G E ++ Q P K + L + + + + SS +P
Sbjct: 524 TRGKKDG-------EISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 576
Query: 508 GFTECEMTKSSPLKITL---FLEEDK--------SLKVTSDPKVEQKIEVIRE-----IE 551
G K S L I + E+ K SL+ TSD K + + RE I
Sbjct: 577 GLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEK-DSFSNITREKKDGEIS 635
Query: 552 MSVDDDDINSSKVINDLFSDVL--EEGELDMEKSQ---EEMDQALAESSEEQEDALNISS 606
V + K +D VL D EKS+ E L +S+E++ LNI+
Sbjct: 636 RKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIAR 695
Query: 607 MSLLAPLAQTVGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAESGDSLGSED 666
+TV P +L +T E S + E+ K G+ RT SG S +
Sbjct: 696 GKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIAREN-KDGEKSRTVSSEKPSGLKATSAE 754
Query: 667 RDLLYSID-----AYRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAFPCQVNIKQKMQ 721
+D + +I +++R ++P++K K+ V EK + + QK
Sbjct: 755 KDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQP 814
Query: 722 ELNNEINMQQTVIYQASQ 739
L + + +V A++
Sbjct: 815 ALKAICDKEDSVPNMATE 832
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 50.8 bits (120), Expect = 7e-06
Identities = 93/400 (23%), Positives = 154/400 (38%), Gaps = 45/400 (11%)
Query: 30 APRSMTHAKRARQPLSEA---SNQQPLSGGEE-------------KSCTKPS-PSKKRCS 72
AP S+T A+ A LS A S + PLS E +S T PS PS+ R +
Sbjct: 2362 APASLTSARMA-PALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMT 2420
Query: 73 DNTEVEVSNLENKQPVEST--SAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGL 130
S+ + P +S A+ SPV Q+ I+ + V S + L
Sbjct: 2421 SERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGS-----QSL 2475
Query: 131 NSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSN 190
+S AT SS L+ + D+ + P +S + PS A P + S+
Sbjct: 2476 SSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGE--PPASTGAQQPSALAALQPAKERRSS 2533
Query: 191 ASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINS 250
+S++ ++ +++ S + S ++ +S+ QP A S +
Sbjct: 2534 SSSSSSSSSSSSSSSSSSSSS-SSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592
Query: 251 SSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCE 310
+ +R +S + + SSS+ +S ++S SSS ++S S++S + + S
Sbjct: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
Query: 311 GQNPELLPKTPISPLK--------TGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKS 362
P+ LPK P SP K KPI S+++ R Q +D+
Sbjct: 2653 KPGPQALPK-PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQ 2711
Query: 363 TTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITP 402
++ ER R Q SP+ TP P
Sbjct: 2712 SSSS--------ERGSRRGQRGDSRSPSHKRRRETPSPRP 2743
Score = 48.5 bits (114), Expect = 3e-05
Identities = 95/489 (19%), Positives = 184/489 (37%), Gaps = 62/489 (12%)
Query: 13 RARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCS 72
R R ++ ++P AAPR+ + + + +P + A P S PS + S
Sbjct: 1594 RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653
Query: 73 DNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNS 132
+ + P +S +A+ S S P+ + + S + P R+ S
Sbjct: 1654 S------TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPEL---TRKARLS 1704
Query: 133 RLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNAS 192
R +A+SS +TR + RR S+ SP P+E+ +S R S+
Sbjct: 1705 RRSRSASSSPETRSRTPPRHRR------------SPSVSSPEPAEKSRSSRRRRSASSPR 1752
Query: 193 ATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSS 252
RRGR + ++ S +E+ T S +S +++R S
Sbjct: 1753 TKTTSRRGRSPS--------PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS 1804
Query: 253 VKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQ 312
+ +R G S + SP + +S T ++ G+
Sbjct: 1805 RSRSRVTRRRRGG-----------------------SGYHSRSPARQESSRTSSRRRRGR 1841
Query: 313 NPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSR-EICLQSQSKDKSTTPGGTGIK 371
+ P T ++ S K + S+ P+ SR L S+ + +S T + +
Sbjct: 1842 S--RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRR 1899
Query: 372 PFLERFGERCQEHSKESPA--RSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQ 429
R + S+ SP R + RTP +T + ++ + S T + ++ +
Sbjct: 1900 SRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSR 1959
Query: 430 ERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVT 489
R + R R I + S++ + T++ + +++P+ + + S+T PVT
Sbjct: 1960 SRTPPVTRRRSRSRTSPI--TRRRSRSRTSPV-TRRRSRSRTSPVTRRRSRSRTS--PVT 2014
Query: 490 EKVTENQIP 498
+ + ++ P
Sbjct: 2015 RRRSRSRTP 2023
Score = 45.8 bits (107), Expect = 2e-04
Identities = 144/696 (20%), Positives = 262/696 (37%), Gaps = 76/696 (10%)
Query: 11 RTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSG-GEEKSCTKPSPSKK 69
RT ARR + + R + RS T A+R R + ++ P G +S + S
Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGR-----SRSRTPRRGRSRSRSLVRRGRSHS 715
Query: 70 RCSDNTEVEVSNLENKQPVESTSAKS---CSPSPVSPQVQPQAADTISDSVAVPASLLGM 126
R S+ E K ++ +S SP ++ + + ++S + S L +
Sbjct: 716 RTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSL 775
Query: 127 RRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRP 186
RR L+ S +T ++ + T S SP P ++K+ +P R
Sbjct: 776 RRSLSGSSPCPKQKS-QTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP-PPKQKSKTPSRQ 833
Query: 187 LLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKF---SSASG 243
S++S P + G + ++ + + +++ + P S+ S SG
Sbjct: 834 SHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSG 893
Query: 244 AS-ARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSS--VKATSPVKST 300
+S R+ SS+ +++ S+ KA+ S + ++S S S T+P +S
Sbjct: 894 SSPPRVKSSTPPRQSP--SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSR 951
Query: 301 TSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD 360
+ C LLP+ S G S P K +T P + S + K
Sbjct: 952 S----VSPCSNVESRLLPRYSHS----GSSSPDTK-VKPETPPRQ---SHSGSISPYPKV 999
Query: 361 KSTTPGGTGIKPFLERFGERC-QEHSKESPARSTPHRTPII------TPNTKA---IQER 410
K+ TP G P L C QE SK+S +S P + TP ++ +
Sbjct: 1000 KAQTPPG----PSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSL 1055
Query: 411 LFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQ 470
K + +S H + E ++ + K ++ KGG S+S T+ +
Sbjct: 1056 QLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ--TSPKGGRSRSSSPVTELASR-- 1111
Query: 471 STPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPK-------GFTECEMTKSSPLKIT 523
+P+++ +G + + E +SS+ P G + E T S K+
Sbjct: 1112 -SPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLE-TAESKEKMA 1169
Query: 524 LFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKS 583
L +ED + S P+ + K V D +S + L + E
Sbjct: 1170 LPPQEDAT---ASPPRQKDKFS-----PFPVQDRPESSLVFKDTLRTPPRERSGAGSSPE 1221
Query: 584 QEEMDQALAESSEEQE-----DALNISSMSLLAPLAQTVGVVSPESLVSTPRLELKD--T 636
+E + AL SS+++E + + +L+ L+ + +S + S+P +E + +
Sbjct: 1222 TKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVS 1281
Query: 637 SRSDESPKPGKFQRTRVPRAES---GDSLGSEDRDL 669
D+S + VP S G E ++L
Sbjct: 1282 LTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKEL 1317
Score = 44.3 bits (103), Expect = 7e-04
Identities = 141/667 (21%), Positives = 238/667 (35%), Gaps = 102/667 (15%)
Query: 18 NLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEV 77
+LQ K + + RS T + RQ SE+ + Q KS T P + R S
Sbjct: 1054 SLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQ------SKSQTSPKGGRSRSSS---- 1103
Query: 78 EVSNLENKQPVESTSAKSCSPSPVSPQVQPQAADTISDSVAVPA----SLLGMRRGLNSR 133
V+ L ++ P+ + + + + P+ + SDS + P SLLG SR
Sbjct: 1104 PVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLG-----QSR 1158
Query: 134 LEATAASSVKTRMQKLAEQRRRWDNDDMTDDIP-ESSLFSPMPSEEKAAS---------- 182
LE TA S K + +D T P + FSP P +++ S
Sbjct: 1159 LE-TAESKEKMALP---------PQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRT 1208
Query: 183 PPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSAS 242
PPR S A ++P + N A S ++++ K E+P LS SS
Sbjct: 1209 PPRE-RSGAGSSPETKE---QNSALPTSSQDEELMEVVEK----SEEPAGQILSHLSSEL 1260
Query: 243 GASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKA-----TSPV 297
+ N S + + +++ L S ASL + S + SP
Sbjct: 1261 KEMSTSNFES-------SPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPE 1313
Query: 298 KSTTSITDAKSCEGQNP-ELLPKTPI-SPLKTGVSKPIVKSTLSQTVPSKGELSREICLQ 355
S + + +P E P+ + + TG S VK L+ ++ E + ++
Sbjct: 1314 HKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSE-VKEDLNGPFLNQLETDPSLDMK 1372
Query: 356 SQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQD 415
QS +S+ + + P S SP RTP +ER
Sbjct: 1373 EQS-TRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTP--------SRER----S 1419
Query: 416 TSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLK 475
+S+S+ + L + + R G+ G + S+ + + P
Sbjct: 1420 SSASSPEMKDGLPRTPSR-------RSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRT 1472
Query: 476 KHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVT 535
+G S+ S P + + + P S + P+ +C L + ++S
Sbjct: 1473 PSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKC-----------LTPQRERS---G 1518
Query: 536 SDPKVEQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESS 595
S+ V+QK + + +S ++ + E E D + +
Sbjct: 1519 SESSVDQK--TVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQR 1576
Query: 596 EEQEDALNISSMSLLAPLAQTVGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVP- 654
+ + S S L+P G SPE + PR + S SD SP+P +P
Sbjct: 1577 SRSGSSPEVDSKSRLSPRRSRSG-SSPE-VKDKPRAAPRAQSGSDSSPEPKAPAPRALPR 1634
Query: 655 RAESGDS 661
R+ SG S
Sbjct: 1635 RSRSGSS 1641
Score = 37.4 bits (85), Expect = 0.081
Identities = 44/177 (24%), Positives = 76/177 (42%), Gaps = 10/177 (5%)
Query: 20 QRKMAERPTAAPRSMTHA-KRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVE 78
Q+K ++ RS + + +R R+ S+ + S +++ P+P KR S + + +
Sbjct: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRK 246
Query: 79 VSNLENKQPVE-----STSAKSCSPSPVS-PQVQPQAADTISDSVA--VPASLLGMR-RG 129
S P STSA S S S S + + AA T + ++A P+ G R G
Sbjct: 247 RSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEG 306
Query: 130 LNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRP 186
E S+ + + A ++ +D D E S P PS E++++ P P
Sbjct: 307 DAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP 363
Score = 35.8 bits (81), Expect = 0.23
Identities = 43/187 (22%), Positives = 64/187 (34%), Gaps = 24/187 (12%)
Query: 22 KMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSN 81
K PT AP+ R +P ++ S S + S S S ++ S+
Sbjct: 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS----SS 2632
Query: 82 LENKQPVESTSAKSCSPSPVS--PQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAA 139
+ S+S+ S SPSP PQ P+ A S P G RR + R +
Sbjct: 2633 SSSSSSSSSSSSSSSSPSPAKPGPQALPKPA---SPKKPPP----GERRSRSPRKPIDSL 2685
Query: 140 SSVKTRMQKLAEQRRRWDNDDMTDDIPESS-----------LFSPMPSEEKAASPPRPLL 188
++ E+RR D SS SP + PRP+
Sbjct: 2686 RDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR 2745
Query: 189 SNASATP 195
+S +P
Sbjct: 2746 HRSSRSP 2752
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 50.1 bits (118), Expect = 1e-05
Identities = 83/434 (19%), Positives = 175/434 (40%), Gaps = 54/434 (12%)
Query: 405 KAIQERLFKQDTSSSTTHLAQQLKQERQ---KELACLRGRFDKGNIWSAEKGGNSKSKQL 461
K ++ K++ QQLK + KEL +R D + N KQL
Sbjct: 721 KDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDL-----VVQERNDAQKQL 775
Query: 462 ETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLK 521
+Q+ L+ SK + L + K ++I ++ + +C + + L
Sbjct: 776 SEEQDARI----LQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIAL- 830
Query: 522 ITLFLEEDKSLKVTSDPKVEQKIEVIRE--------IEMSVD---------DDDINSSKV 564
+ L ++ K+ + K + IE ++E I+++ + +N+
Sbjct: 831 LRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTA 890
Query: 565 INDLFSDVLEEGELDMEKSQEEMDQ---ALAESSEEQEDALNISSMSLLAPLAQTVGVVS 621
N + + LE G+ + E+ + EM+ LA + + + + + L + V
Sbjct: 891 ENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRL 950
Query: 622 PESL-VSTPRLELKDTSRSDE-SPKPGKFQRTRVPRAESGDSLGSED-------RDLLYS 672
+ + V L+ K+ S++ S K ++ + D+LG E RDL +
Sbjct: 951 HDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQT 1010
Query: 673 -IDAYRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAFPCQVNIKQKMQELNNEINMQQ 731
+++ + E+ +K+ I ++E V +L + + + ++Q++ + + + N Q+
Sbjct: 1011 QCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSE---NMLLRQQLDDAHKKANSQE 1067
Query: 732 TVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKRTLLIDELNKLKNEGPQ-RKNK 790
+ + D+ H +AE+E+ +L K L+DE N LK Q K K
Sbjct: 1068 -------KTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEK 1120
Query: 791 ASPQSEFMPSKGSV 804
A + + ++ +V
Sbjct: 1121 AGRKIDLTEAQETV 1134
>gi|110349763 cytohesin 1 isoform 2 [Homo sapiens]
Length = 397
Score = 49.3 bits (116), Expect = 2e-05
Identities = 33/106 (31%), Positives = 53/106 (50%), Gaps = 20/106 (18%)
Query: 1002 WHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITV 1061
W RRW +L+ NC+ Y+ Y D K P G I L N + R++E + + C FEL
Sbjct: 277 WKRRWFILTDNCLYYFEYTTD---KEPRGIIPLENLSIREVEDSKKPNC-----FELYI- 327
Query: 1062 RPQREDDRETLVSQCR---DTLCVTKNW----LSADTKEERDLWMQ 1100
D+++ ++ C+ D V N +SA T EE++ W++
Sbjct: 328 ----PDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIK 369
>gi|4758964 cytohesin 1 isoform 1 [Homo sapiens]
Length = 398
Score = 49.3 bits (116), Expect = 2e-05
Identities = 33/106 (31%), Positives = 53/106 (50%), Gaps = 20/106 (18%)
Query: 1002 WHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITV 1061
W RRW +L+ NC+ Y+ Y D K P G I L N + R++E + + C FEL
Sbjct: 278 WKRRWFILTDNCLYYFEYTTD---KEPRGIIPLENLSIREVEDSKKPNC-----FELYI- 328
Query: 1062 RPQREDDRETLVSQCR---DTLCVTKNW----LSADTKEERDLWMQ 1100
D+++ ++ C+ D V N +SA T EE++ W++
Sbjct: 329 ----PDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIK 370
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 48.9 bits (115), Expect = 3e-05
Identities = 74/317 (23%), Positives = 124/317 (39%), Gaps = 45/317 (14%)
Query: 413 KQDTSSSTTHLAQQLKQERQKELAC-------LRGRFDKGNIWSAEKGGNSKSKQLETKQ 465
KQ T S+ + +++ K+LAC RG +DK + E G + +K + K
Sbjct: 2811 KQRTEMSSKAMPDSFSEQQAKDLACHITSDLATRGPWDKKVFRTWESSGATNNKSQKEKL 2870
Query: 466 ETHCQSTPLKKHQGVSKTQS-------LPVTEKVTENQIPAKNSSTEPKGFTECEMTKSS 518
+ H G +++S + VTE+ E ++ S +E K EMT S
Sbjct: 2871 SHVLVHDVRENHIGHPESKSVDQKNEFMSVTER--ERKLLTNGSLSEIK-----EMTVKS 2923
Query: 519 PLKITLFLEE-----DKSLKVTSDPKVEQKIEVIREIEMSVDDDDINSSKVINDLFSD-- 571
P K L+ E D + P + + I + V D+ S I D F +
Sbjct: 2924 PSKKVLYREYVVKEGDHPGGLLDQPSRRSESSAVSHIPVRVADERRMLSSNIPDGFCEQS 2983
Query: 572 VLEEGELDMEKSQEEMDQALAES-------------SEEQEDALNISSMSLLAPL--AQT 616
+ EL + SQ M + E+ SE + + + S + L PL +T
Sbjct: 2984 AFPKHELSQKLSQSSMSKETVETQHFNSIEDEKVTYSEISKVSKHQSYVGLCPPLEETET 3043
Query: 617 VGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAESGDSLGSEDRDLLYSIDAY 676
SP+SL +P E + D SP G + + + E G + + + S
Sbjct: 3044 SPTKSPDSLEFSPGKESPSSDVFDHSPIDGLEKLAPLAQTEGGKEI--KTLPVYVSFVQV 3101
Query: 677 RSQRFKETERPSIKQVI 693
Q KE ++ +K++I
Sbjct: 3102 GKQYEKEIQQGGVKKII 3118
>gi|195972859 cytohesin 2 isoform 2 [Homo sapiens]
Length = 399
Score = 48.1 bits (113), Expect = 5e-05
Identities = 33/108 (30%), Positives = 53/108 (49%), Gaps = 20/108 (18%)
Query: 1002 WHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITV 1061
W RRW +L+ NC+ Y+ Y D K P G I L N + R+++ + C FEL
Sbjct: 276 WKRRWFILTDNCLYYFEYTTD---KEPRGIIPLENLSIREVDDPRKPNC-----FELYI- 326
Query: 1062 RPQREDDRETLVSQCR---DTLCVTKNW----LSADTKEERDLWMQKL 1102
+++ L+ C+ D V N +SA T+EE+D W++ +
Sbjct: 327 ----PNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSI 370
>gi|8670546 cytohesin 2 isoform 1 [Homo sapiens]
Length = 400
Score = 48.1 bits (113), Expect = 5e-05
Identities = 33/108 (30%), Positives = 53/108 (49%), Gaps = 20/108 (18%)
Query: 1002 WHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITV 1061
W RRW +L+ NC+ Y+ Y D K P G I L N + R+++ + C FEL
Sbjct: 277 WKRRWFILTDNCLYYFEYTTD---KEPRGIIPLENLSIREVDDPRKPNC-----FELYI- 327
Query: 1062 RPQREDDRETLVSQCR---DTLCVTKNW----LSADTKEERDLWMQKL 1102
+++ L+ C+ D V N +SA T+EE+D W++ +
Sbjct: 328 ----PNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSI 371
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 47.8 bits (112), Expect = 6e-05
Identities = 82/387 (21%), Positives = 151/387 (39%), Gaps = 43/387 (11%)
Query: 246 ARINSS--SVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSI 303
+RINSS S + F R G K ++ + S +K + K+
Sbjct: 178 SRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKE 237
Query: 304 TDAKSCEGQNPELLPKTPISPLKTGVS-----KPIVKSTLSQTVPSKGELSREICLQSQS 358
+ K + + +L L+TG K + +TV SK + + S+
Sbjct: 238 RERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEE 297
Query: 359 KDKSTTPG---GTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQD 415
K ++ T G K ++ ++ ++ KE + P + + KA+QE L K
Sbjct: 298 KAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATV-----KAMQEALAKLK 352
Query: 416 TSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLK 475
++ + +R +EL R ++ EK K K+ E K+ + L
Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEER---LEQEKRERKKQKEKERKERLKKEGKLLT 409
Query: 476 KHQGVSKTQSLPVTEKVTENQ---IPAKNSSTEPKGFTECEMTKSSPLKITL-------- 524
K Q ++ ++ T K+ + Q +P+K+S + + E + K P ++
Sbjct: 410 KSQREARARA-EATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESME 468
Query: 525 ------FLEEDKSLKVTSDPKVEQKIEVIREIEMSVDD-----DDINSSKVI-NDLFSDV 572
+E+ K + P VE + E E + +DD D + KV N + +V
Sbjct: 469 LCAAVEVMEQGVPEKEETPPPVEPEEEEDTE-DAGLDDWEAMASDEETEKVEGNKVHIEV 527
Query: 573 LEEGELDMEKSQEEMDQALAESSEEQE 599
E E + E+ +EE + +E EE+E
Sbjct: 528 KENPEEEEEEEEEEEEDEESEEEEEEE 554
Score = 33.5 bits (75), Expect = 1.2
Identities = 62/309 (20%), Positives = 118/309 (38%), Gaps = 31/309 (10%)
Query: 527 EEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDIN----------SSKVINDLFSDVLEEG 576
E D+ L+ K QK + IE +DDD + + K + E+
Sbjct: 189 ESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKA 248
Query: 577 ELDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVV-SPESLVSTPRLELKD 635
+L K +EE++ + S+++E ++ + + GV+ + E TP +D
Sbjct: 249 KLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETP-TAAED 307
Query: 636 TSRSDESPKPGKFQRTRVPRAESGDSLGSEDRDLLYSIDAY-RSQRFKETERPSIKQVIV 694
+ D+ K K ++ E G + +A + + +E ++ ++ I
Sbjct: 308 DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIK 367
Query: 695 RKEDVTSKLDEKNNAFPCQVNIKQKMQELNNEINMQQTVIYQASQALNCCVDEEHGKGSL 754
R E++ +K E+ + K++ ++ E ++ + SQ + +
Sbjct: 368 RLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQ-----------REAR 416
Query: 755 EEAEAERLLLIATGKRTLLIDELNKLKNEGPQRKNKASPQ-------SEFMPSKGSVTLS 807
AEA LL A G D L K + +K K PQ SE M +V +
Sbjct: 417 ARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVM 476
Query: 808 EIRLPLKAD 816
E +P K +
Sbjct: 477 EQGVPEKEE 485
>gi|239047795 pleckstrin homology domain containing, family A member 7
[Homo sapiens]
Length = 1121
Score = 47.4 bits (111), Expect = 8e-05
Identities = 43/169 (25%), Positives = 76/169 (44%), Gaps = 14/169 (8%)
Query: 944 SYTLSLSSVGNTKFVLDKVP----FLSSLEGHIYLK----IKCQVNSSVEERGFLTIFED 995
S +S +S T L+ P SS + H + K I+ N V RG+L +D
Sbjct: 117 SSMVSETSTAGTASTLEAKPGPKIIKSSSKVHSFGKRDQAIRRNPNVPVVVRGWLHK-QD 175
Query: 996 VSGFGAWHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQIEPANREFCARRNT 1055
SG W RRW VL+ C+ Y+ D + + +G I L + + P +R +R+ +
Sbjct: 176 SSGMRLWKRRWFVLADYCLFYY---KDSREEAVLGSIPLPSYVISPVAPEDR--ISRKYS 230
Query: 1056 FELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQKLNQ 1104
F+ + + + + + + SADT+E+ + W++ +NQ
Sbjct: 231 FKAVHTGMRALIYNSSTAGSQAEQSGMRTYYFSADTQEDMNAWVRAMNQ 279
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 47.4 bits (111), Expect = 8e-05
Identities = 137/687 (19%), Positives = 251/687 (36%), Gaps = 83/687 (12%)
Query: 101 VSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAE------QRR 154
VSP+ P T+ DS + LG L S E++ + T K A+ RR
Sbjct: 196 VSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRR 255
Query: 155 RWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASAT----PV-GRRGRLANLAATI 209
+ D P + S EKA S + +SN + P+ G A
Sbjct: 256 K-------DSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKA 308
Query: 210 CSWEDDVNHSFAKQNSVQEQPGTACLSKFSS-----------------ASGASARINSSS 252
S E D + A + +Q GT K S+ +G SS
Sbjct: 309 TSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSS 368
Query: 253 VKQEATFCSQRDGDASLNKALS-SSADDASLVNASISSSVKATSPVKSTTS--ITDAKSC 309
KQ + + D++LN A V++ ++KAT+ + + S T+ K
Sbjct: 369 QKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDG 428
Query: 310 EGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGGTG 369
E K P T ++ T GE S + Q Q K+TT
Sbjct: 429 EKSGTVSSQKQPALKATTDEEDSVLNIA---TEIKDGEKSETVSSQKQPALKATTDEEDS 485
Query: 370 IKPFLERF--GERCQE-HSKESPA-RSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQ 425
+ GE+ S++ PA ++T + T+ ++ + SS +
Sbjct: 486 VSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 545
Query: 426 QLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQS 485
E L+ R E+ KS+ + ++Q ++T +K ++ +
Sbjct: 546 ATSDEEDSVLSIAR-----------EEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARG 594
Query: 486 LPVTEK---VTENQIPAKNSSTE-----PKGFTECEMTKSSPLKITLFLEEDKSLKVTSD 537
EK V+ ++ PA ++++ P TE TK + T+ ++ +LK TSD
Sbjct: 595 KKYGEKTRRVSSHKQPALKATSDKENSVPNMATE---TKDEQISGTVSSQKQPALKATSD 651
Query: 538 PKVEQKIEVIREIEMSVDDDDINSSK--------VINDLFSDV---LEEGELDMEKSQEE 586
K + + EI+ ++S K V D S++ +++G++ S +
Sbjct: 652 KK-DSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQR 710
Query: 587 MDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPESLVSTPRLELKDTSRSDESPKPG 646
AL + +E++ NI+ + G VSP+ + + K S + + +
Sbjct: 711 QP-ALKATGDEKDSVSNIARE---IKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRIT 766
Query: 647 KFQRTRVPRAESGDSLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLDEK 706
++ E+ +L + + ++ + +T P+ + + + E +L+E
Sbjct: 767 GGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEY 826
Query: 707 NNAFPCQVNIKQKMQELNNEINMQQTV 733
N P N +L++ I QTV
Sbjct: 827 ENNQPQVKNQIHSRDDLDDIIQSSQTV 853
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 47.4 bits (111), Expect = 8e-05
Identities = 138/645 (21%), Positives = 232/645 (35%), Gaps = 93/645 (14%)
Query: 27 PTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQ 86
P ++ AKRA++P E+ + + S EE++ K +V ++
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS----A 305
Query: 87 PVESTSAKSCSPSP------VSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAAS 140
P + T K +P+P V+ Q + + S+S + +S +S E AA
Sbjct: 306 PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESS--------DSEEETPAA- 356
Query: 141 SVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRG 200
K +Q A + T + +S P++E PR A+ P G+ G
Sbjct: 357 --KALLQAKASGK--------TSQVGAAS----APAKES----PR---KGAAPAPPGKTG 395
Query: 201 RLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLS-KFSSASGASARINSSSVKQEATF 259
A A E+D S + +S +E P A S K ASA S K A
Sbjct: 396 P-AVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 260 CSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAK-SCEGQNPELLP 318
++ G A+ + +D S SSS ++ S ++ ++ A+ G++P++ P
Sbjct: 455 PPRKTGPAAAQVQVGKQEED------SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
Query: 319 KTP--ISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGG---TGIKPF 373
+ + PL G P+ + PS E +S S++ S + G T + P
Sbjct: 509 ASTMGMGPLGKGAG-PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA 567
Query: 374 LER-FGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQ 432
E+ G Q SPA+ P + + KA ++ + ++S ++ A +
Sbjct: 568 QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA-EKPMDNSESSEESSDSADSEEAPAA 626
Query: 433 KELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKV 492
A + + K N+ + Q+ P K S S P
Sbjct: 627 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQA-PRKAGTATSPAGSSPAVAGG 685
Query: 493 TENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEM 552
T Q PA++SS+ + +E EE L VT V Q V + +++
Sbjct: 686 T--QRPAEDSSSSEESDSE---------------EEKTGLAVT----VGQAKSVGKGLQV 724
Query: 553 SVDDDDINSS----------KVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDAL 602
+ S + V E + D E S+EE D A +S Q
Sbjct: 725 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784
Query: 603 NISSMSLLAPLA----QTVGVVSPESLVSTPRLELKDTSRSDESP 643
+ + P A G +S V T + K S S P
Sbjct: 785 VKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 829
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 47.4 bits (111), Expect = 8e-05
Identities = 138/645 (21%), Positives = 232/645 (35%), Gaps = 93/645 (14%)
Query: 27 PTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQ 86
P ++ AKRA++P E+ + + S EE++ K +V ++
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS----A 305
Query: 87 PVESTSAKSCSPSP------VSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAAS 140
P + T K +P+P V+ Q + + S+S + +S +S E AA
Sbjct: 306 PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESS--------DSEEETPAA- 356
Query: 141 SVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRG 200
K +Q A + T + +S P++E PR A+ P G+ G
Sbjct: 357 --KALLQAKASGK--------TSQVGAAS----APAKES----PR---KGAAPAPPGKTG 395
Query: 201 RLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLS-KFSSASGASARINSSSVKQEATF 259
A A E+D S + +S +E P A S K ASA S K A
Sbjct: 396 P-AVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 260 CSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAK-SCEGQNPELLP 318
++ G A+ + +D S SSS ++ S ++ ++ A+ G++P++ P
Sbjct: 455 PPRKTGPAAAQVQVGKQEED------SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
Query: 319 KTP--ISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGG---TGIKPF 373
+ + PL G P+ + PS E +S S++ S + G T + P
Sbjct: 509 ASTMGMGPLGKGAG-PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA 567
Query: 374 LER-FGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQ 432
E+ G Q SPA+ P + + KA ++ + ++S ++ A +
Sbjct: 568 QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA-EKPMDNSESSEESSDSADSEEAPAA 626
Query: 433 KELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKV 492
A + + K N+ + Q+ P K S S P
Sbjct: 627 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQA-PRKAGTATSPAGSSPAVAGG 685
Query: 493 TENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEM 552
T Q PA++SS+ + +E EE L VT V Q V + +++
Sbjct: 686 T--QRPAEDSSSSEESDSE---------------EEKTGLAVT----VGQAKSVGKGLQV 724
Query: 553 SVDDDDINSS----------KVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDAL 602
+ S + V E + D E S+EE D A +S Q
Sbjct: 725 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784
Query: 603 NISSMSLLAPLA----QTVGVVSPESLVSTPRLELKDTSRSDESP 643
+ + P A G +S V T + K S S P
Sbjct: 785 VKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 829
Score = 38.9 bits (89), Expect = 0.028
Identities = 84/365 (23%), Positives = 143/365 (39%), Gaps = 66/365 (18%)
Query: 33 SMTHAKRARQPLSEASNQQPLSGGEEKSCT----KPSPSKKRCSDNTEVEVS-------N 81
++T K +Q SE+S ++ S EE + + K S K + N + +
Sbjct: 750 TVTQVKAEKQEDSESSEEE--SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTIS 807
Query: 82 LENKQPVESTSAKSCSPSPVSPQVQ-PQAADTISDSVAVPASLLGMRRGLNSRLEA---- 136
K + AK SPS V P V+ PQ + ++ PAS+ + + + + +A
Sbjct: 808 APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARG---PASVPSVGKAVATAAQAQTGP 864
Query: 137 ---TAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASA 193
+ +S ++ ++ AE + T I ++L S K A+P P + SA
Sbjct: 865 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQI-RAALAPAKESPRKGAAPTPPGKTGPSA 923
Query: 194 TPVGRRGRLANLA----------ATICSWED--------DVNHSFAKQNSVQEQPGTACL 235
G++ + + A + S + D N S A + Q A
Sbjct: 924 AQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAST 983
Query: 236 SKFSSASGASARINSSSVKQE----ATFCSQ---RDGDASLNKALSSSADDASLVNASIS 288
+ + AS ++AR +SS + E AT C R ++ A A AS+ AS S
Sbjct: 984 PRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSS 1043
Query: 289 SSVKATSPVKSTTSITDAKSCEGQNPELLPKTPIS-PLKTGVSKPIVKST------LSQT 341
K ++ I+D K EG ++ K P S PL K + + +++T
Sbjct: 1044 ---------KESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVART 1094
Query: 342 VPSKG 346
PS G
Sbjct: 1095 QPSSG 1099
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 47.4 bits (111), Expect = 8e-05
Identities = 138/645 (21%), Positives = 232/645 (35%), Gaps = 93/645 (14%)
Query: 27 PTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQ 86
P ++ AKRA++P E+ + + S EE++ K +V ++
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS----A 305
Query: 87 PVESTSAKSCSPSP------VSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAAS 140
P + T K +P+P V+ Q + + S+S + +S +S E AA
Sbjct: 306 PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESS--------DSEEETPAA- 356
Query: 141 SVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRG 200
K +Q A + T + +S P++E PR A+ P G+ G
Sbjct: 357 --KALLQAKASGK--------TSQVGAAS----APAKES----PR---KGAAPAPPGKTG 395
Query: 201 RLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLS-KFSSASGASARINSSSVKQEATF 259
A A E+D S + +S +E P A S K ASA S K A
Sbjct: 396 P-AVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 260 CSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAK-SCEGQNPELLP 318
++ G A+ + +D S SSS ++ S ++ ++ A+ G++P++ P
Sbjct: 455 PPRKTGPAAAQVQVGKQEED------SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
Query: 319 KTP--ISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGG---TGIKPF 373
+ + PL G P+ + PS E +S S++ S + G T + P
Sbjct: 509 ASTMGMGPLGKGAG-PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA 567
Query: 374 LER-FGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQ 432
E+ G Q SPA+ P + + KA ++ + ++S ++ A +
Sbjct: 568 QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA-EKPMDNSESSEESSDSADSEEAPAA 626
Query: 433 KELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKV 492
A + + K N+ + Q+ P K S S P
Sbjct: 627 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQA-PRKAGTATSPAGSSPAVAGG 685
Query: 493 TENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEM 552
T Q PA++SS+ + +E EE L VT V Q V + +++
Sbjct: 686 T--QRPAEDSSSSEESDSE---------------EEKTGLAVT----VGQAKSVGKGLQV 724
Query: 553 SVDDDDINSS----------KVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDAL 602
+ S + V E + D E S+EE D A +S Q
Sbjct: 725 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784
Query: 603 NISSMSLLAPLA----QTVGVVSPESLVSTPRLELKDTSRSDESP 643
+ + P A G +S V T + K S S P
Sbjct: 785 VKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 829
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 47.4 bits (111), Expect = 8e-05
Identities = 138/645 (21%), Positives = 232/645 (35%), Gaps = 93/645 (14%)
Query: 27 PTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQ 86
P ++ AKRA++P E+ + + S EE++ K +V ++
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS----A 305
Query: 87 PVESTSAKSCSPSP------VSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAAS 140
P + T K +P+P V+ Q + + S+S + +S +S E AA
Sbjct: 306 PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESS--------DSEEETPAA- 356
Query: 141 SVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRG 200
K +Q A + T + +S P++E PR A+ P G+ G
Sbjct: 357 --KALLQAKASGK--------TSQVGAAS----APAKES----PR---KGAAPAPPGKTG 395
Query: 201 RLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLS-KFSSASGASARINSSSVKQEATF 259
A A E+D S + +S +E P A S K ASA S K A
Sbjct: 396 P-AVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 260 CSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAK-SCEGQNPELLP 318
++ G A+ + +D S SSS ++ S ++ ++ A+ G++P++ P
Sbjct: 455 PPRKTGPAAAQVQVGKQEED------SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
Query: 319 KTP--ISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGG---TGIKPF 373
+ + PL G P+ + PS E +S S++ S + G T + P
Sbjct: 509 ASTMGMGPLGKGAG-PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA 567
Query: 374 LER-FGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQ 432
E+ G Q SPA+ P + + KA ++ + ++S ++ A +
Sbjct: 568 QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA-EKPMDNSESSEESSDSADSEEAPAA 626
Query: 433 KELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKV 492
A + + K N+ + Q+ P K S S P
Sbjct: 627 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQA-PRKAGTATSPAGSSPAVAGG 685
Query: 493 TENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEM 552
T Q PA++SS+ + +E EE L VT V Q V + +++
Sbjct: 686 T--QRPAEDSSSSEESDSE---------------EEKTGLAVT----VGQAKSVGKGLQV 724
Query: 553 SVDDDDINSS----------KVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDAL 602
+ S + V E + D E S+EE D A +S Q
Sbjct: 725 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784
Query: 603 NISSMSLLAPLA----QTVGVVSPESLVSTPRLELKDTSRSDESP 643
+ + P A G +S V T + K S S P
Sbjct: 785 VKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 829
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 45.1 bits (105), Expect = 4e-04
Identities = 107/555 (19%), Positives = 201/555 (36%), Gaps = 90/555 (16%)
Query: 295 SPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPI---VKSTLSQ-------TVPS 344
SP+ T + K+ +L+ K +KT K I VK TLS T
Sbjct: 1135 SPMPVPTESSSQKTAVPPQVKLVKKQE-QEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 345 KGELSR-EICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPN 403
K E S+ E S ++K P + P E+ ++ E + + +
Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK 1253
Query: 404 TKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGR--------FDKGNIWSAEKGGN 455
T A +E+ K D S +A++ + R G+ G S K +
Sbjct: 1254 TSAPEEQ--KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDD 1311
Query: 456 SKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMT 515
+K ++ + + C + P + G KT+ + +Q P G++ ++
Sbjct: 1312 KTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGIS 1371
Query: 516 KS----------------SPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDI 559
S LK F +E + K+E + I E + S D+
Sbjct: 1372 SSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEK 1431
Query: 560 NSSKVINDLFSDVLEEGELDMEKSQEEMD--------QALAESSEEQEDALNISSMSLLA 611
+ K +V E D EK+Q + + + ES EE++D S +
Sbjct: 1432 SEKKTQPH---EVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIP 1488
Query: 612 PLA---QTVGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAESGDSLGSEDRD 668
+ V + P ++++S S+ SP P + +RT S+GS
Sbjct: 1489 SSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRT---------SVGSS--- 1536
Query: 669 LLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAFPCQVNIKQKMQELNNEIN 728
S D Y+ + +++ ++ +RK+ + DE + I+ +++E+++
Sbjct: 1537 ---SSDEYKQE---DSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTE 1590
Query: 729 MQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIAT-------GKRTLLIDELNKLK 781
Q+ +E GKG + + RL ++ G+R DE ++
Sbjct: 1591 SQKK-------------EETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAF 1637
Query: 782 NEGPQRKNKASPQSE 796
+E P+ K + + E
Sbjct: 1638 DESPELKYRETKSQE 1652
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 45.1 bits (105), Expect = 4e-04
Identities = 107/555 (19%), Positives = 201/555 (36%), Gaps = 90/555 (16%)
Query: 295 SPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPI---VKSTLSQ-------TVPS 344
SP+ T + K+ +L+ K +KT K I VK TLS T
Sbjct: 1135 SPMPVPTESSSQKTAVPPQVKLVKKQE-QEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 345 KGELSR-EICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPN 403
K E S+ E S ++K P + P E+ ++ E + + +
Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK 1253
Query: 404 TKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGR--------FDKGNIWSAEKGGN 455
T A +E+ K D S +A++ + R G+ G S K +
Sbjct: 1254 TSAPEEQ--KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDD 1311
Query: 456 SKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMT 515
+K ++ + + C + P + G KT+ + +Q P G++ ++
Sbjct: 1312 KTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGIS 1371
Query: 516 KS----------------SPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDI 559
S LK F +E + K+E + I E + S D+
Sbjct: 1372 SSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEK 1431
Query: 560 NSSKVINDLFSDVLEEGELDMEKSQEEMD--------QALAESSEEQEDALNISSMSLLA 611
+ K +V E D EK+Q + + + ES EE++D S +
Sbjct: 1432 SEKKTQPH---EVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIP 1488
Query: 612 PLA---QTVGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAESGDSLGSEDRD 668
+ V + P ++++S S+ SP P + +RT S+GS
Sbjct: 1489 SSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRT---------SVGSS--- 1536
Query: 669 LLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAFPCQVNIKQKMQELNNEIN 728
S D Y+ + +++ ++ +RK+ + DE + I+ +++E+++
Sbjct: 1537 ---SSDEYKQE---DSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTE 1590
Query: 729 MQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIAT-------GKRTLLIDELNKLK 781
Q+ +E GKG + + RL ++ G+R DE ++
Sbjct: 1591 SQKK-------------EETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAF 1637
Query: 782 NEGPQRKNKASPQSE 796
+E P+ K + + E
Sbjct: 1638 DESPELKYRETKSQE 1652
>gi|4758968 cytohesin 3 [Homo sapiens]
Length = 399
Score = 45.1 bits (105), Expect = 4e-04
Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 20/108 (18%)
Query: 1002 WHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITV 1061
W RRW +L+ NC+ Y+ Y D K P G I L N + R++E + C FEL
Sbjct: 281 WKRRWFILTDNCLYYFEYTTD---KEPRGIIPLENLSIREVEDPRKPNC-----FEL--- 329
Query: 1062 RPQREDDRETLVSQCR---DTLCVTKNW----LSADTKEERDLWMQKL 1102
+ ++ C+ D V N +SA + EE++ WM+ +
Sbjct: 330 --YNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSI 375
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 44.7 bits (104), Expect = 5e-04
Identities = 107/529 (20%), Positives = 185/529 (34%), Gaps = 57/529 (10%)
Query: 30 APRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVE 89
A + + K A+ P+ E + + EK K SP++ + + + P
Sbjct: 506 AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK-SPAEVKSPEKAKSPAKEEAKSPPEA 564
Query: 90 STSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLN-----SRLEATAASSVKT 144
+ K + SP + +A + PA + + ++ A A S VK
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Query: 145 RMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRGRLAN 204
+ AE + T + +S + P +E+A SP + + +PV +
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK------AKSPVKAEAKSPE 678
Query: 205 LAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRD 264
A + E AK + P + S A + + + E ++
Sbjct: 679 KAKSPVKAE-------AKSPEKAKSP---VKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728
Query: 265 GDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISP 324
+ KA S ++A + S T VKS + T AK + P+ SP
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788
Query: 325 LKTGVSKP-IVKSTLSQTVPS-KGELSREICLQSQSKDKSTTPGGTGIKPFLERFGERCQ 382
+K V P KS L + + + E+ ++ ++S K++ E+ Q
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEE-----------------EKPQ 831
Query: 383 EHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRF 442
E + P + TP T+ ++ ++ A + K E +KE A + +
Sbjct: 832 EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE----APKPKVEEKKEPAVEKPKE 887
Query: 443 DKGNIWSAEKGGNSK----SKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIP 498
K E K K+ K E + P +K + K P K E P
Sbjct: 888 SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKE---PDDAKAKEPSKP 944
Query: 499 AKNSSTEP-KGFTECEMTK---SSPLKITLFLEEDKSL-KVTSDPKVEQ 542
A+ P K T+ E K P E+DK+L K S PK E+
Sbjct: 945 AEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 993
Score = 38.9 bits (89), Expect = 0.028
Identities = 114/538 (21%), Positives = 198/538 (36%), Gaps = 66/538 (12%)
Query: 254 KQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAKS-CEGQ 312
++EA + +A S + S V S +A SP K +AKS E +
Sbjct: 491 EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE-----EAKSPAEVK 545
Query: 313 NPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGGTGIKP 372
+PE K+P + S P KS + S E+ +S +K+++ +P
Sbjct: 546 SPEKA-KSPAK--EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA---- 598
Query: 373 FLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQ 432
+ E+ + KE ++P+ K+ E + S T A+ ++ +
Sbjct: 599 ---KSPEKAKSPVKEEAKSPAEAKSPV-KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654
Query: 433 KELACLRGRFDKGNIWSAEKGGNSKSK---QLETKQETHCQSTPLKKHQGVSKTQSLPVT 489
E + + AE K+K + E K +S P+K+ + PV
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKS-PVKEEAKSPEKAKSPVK 713
Query: 490 EKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIRE 549
E E + P K S + E KS P+K EE KS + P+ + ++V
Sbjct: 714 E---EAKSPEKAKSPVKEEAKTPEKAKS-PVK-----EEAKSPEKAKSPEKAKTLDVKSP 764
Query: 550 IEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDAL----NIS 605
+ ++ S D F + + + KS E+ L E ++ E + +
Sbjct: 765 EAKTPAKEEARSPA---DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821
Query: 606 SMSLLAPLAQTVGVVSP------ESLVSTPRLELKDTSRSDESPK----PGKFQRTRVPR 655
S Q V V P E +TP+ E K S+ +E+PK K + + P
Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881
Query: 656 AE-------SGDSLGSEDRDLLYS--IDAYRSQRFKETERPSIKQVIVRKE------DVT 700
E +ED+ + + +A KE +P K + +KE
Sbjct: 882 VEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941
Query: 701 SKLDEKNNAFPCQVNIKQKMQELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAE 758
SK EK A P + + K++ + E + + + L+ +E K E+AE
Sbjct: 942 SKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS----KEPSKPKAEKAE 995
Score = 32.0 bits (71), Expect = 3.4
Identities = 61/292 (20%), Positives = 108/292 (36%), Gaps = 43/292 (14%)
Query: 415 DTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPL 474
+ + T + +++ +E +KE G+ ++G +GG ++K S P
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETK-----------SPPA 506
Query: 475 KKHQGVSKTQSLPVTEKV---TENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKS 531
++ K PV E+ E + P K + P E K SP K EE KS
Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK-SPAK-----EEAKS 560
Query: 532 LKVTSDPKVEQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDME-KSQEEMDQA 590
P+ E E + + +K S EE + E KS E+
Sbjct: 561 PPEAKSPEKE-------EAKSPAEVKSPEKAK------SPAKEEAKSPAEAKSPEKAKSP 607
Query: 591 LAESSEEQEDALNISSMSLLAPLAQTVGVVSPESLVSTPRLELKDTSRS-----DESPKP 645
+ E ++ +A + +P V SPE S + E K ++ +E+ P
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSP----AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP 663
Query: 646 GKFQRTRVPRAESGDSLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKE 697
K + A+S + S + S + +S +E + P + V++E
Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 715
>gi|56549111 optineurin [Homo sapiens]
Length = 577
Score = 44.3 bits (103), Expect = 7e-04
Identities = 84/437 (19%), Positives = 177/437 (40%), Gaps = 54/437 (12%)
Query: 381 CQEHSKESPARSTPHRTPIIT-PNTKAIQ-ERLFKQDTSSSTTHLAQQLKQERQKELACL 438
C ++SP+ ST + P + PN E L +Q T + QLK+ + +
Sbjct: 8 CLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTEN--HQLKEAMKLNNQAM 65
Query: 439 RGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIP 498
+GRF++ + W+ KQ E +Q QS K+ ++ + E++ + +
Sbjct: 66 KGRFEELSAWT--------EKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGK 117
Query: 499 AKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDD 558
++ SS +P + ++ K L ++ V + + ++ E+++
Sbjct: 118 SERSSEDPTDDSRLPRAEAEQEKDQL-----RTQVVRLQAEKADLLGIVSELQLK----- 167
Query: 559 INSSKVINDLFSDV-LEEGELDMEKSQEEMDQ------------ALAESSEEQEDA---- 601
+NSS D F ++ + EGE E S +E+ AL++ D
Sbjct: 168 LNSSGSSEDSFVEIRMAEGEA--EGSVKEIKHSPGPTRTVSTGTALSKYRSRSADGAKNY 225
Query: 602 -----LNISSMSLLA----PLAQTVGVVSPESLVSTPRLELKDTSRSD-ESPKPGKFQRT 651
L +S + L + + V E+ E K ++RS+ E+ G ++
Sbjct: 226 FEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKE 285
Query: 652 RVPRAESGDSLGSEDRDLLYSIDA-YRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAF 710
+ +++GSE L + + ++ + T+ + + R ++ L+ KN+A
Sbjct: 286 N-DEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAI 344
Query: 711 PCQVNIKQKMQELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKR 770
P ++N KQ++ N ++ +Q + + ++E K ++ + +LL
Sbjct: 345 PSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQ-EHNNA 403
Query: 771 TLLIDELNKLKNEGPQR 787
I+EL + ++E R
Sbjct: 404 LKTIEELTRKESEKVDR 420
>gi|56549109 optineurin [Homo sapiens]
Length = 577
Score = 44.3 bits (103), Expect = 7e-04
Identities = 84/437 (19%), Positives = 177/437 (40%), Gaps = 54/437 (12%)
Query: 381 CQEHSKESPARSTPHRTPIIT-PNTKAIQ-ERLFKQDTSSSTTHLAQQLKQERQKELACL 438
C ++SP+ ST + P + PN E L +Q T + QLK+ + +
Sbjct: 8 CLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTEN--HQLKEAMKLNNQAM 65
Query: 439 RGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIP 498
+GRF++ + W+ KQ E +Q QS K+ ++ + E++ + +
Sbjct: 66 KGRFEELSAWT--------EKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGK 117
Query: 499 AKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDD 558
++ SS +P + ++ K L ++ V + + ++ E+++
Sbjct: 118 SERSSEDPTDDSRLPRAEAEQEKDQL-----RTQVVRLQAEKADLLGIVSELQLK----- 167
Query: 559 INSSKVINDLFSDV-LEEGELDMEKSQEEMDQ------------ALAESSEEQEDA---- 601
+NSS D F ++ + EGE E S +E+ AL++ D
Sbjct: 168 LNSSGSSEDSFVEIRMAEGEA--EGSVKEIKHSPGPTRTVSTGTALSKYRSRSADGAKNY 225
Query: 602 -----LNISSMSLLA----PLAQTVGVVSPESLVSTPRLELKDTSRSD-ESPKPGKFQRT 651
L +S + L + + V E+ E K ++RS+ E+ G ++
Sbjct: 226 FEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKE 285
Query: 652 RVPRAESGDSLGSEDRDLLYSIDA-YRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAF 710
+ +++GSE L + + ++ + T+ + + R ++ L+ KN+A
Sbjct: 286 N-DEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAI 344
Query: 711 PCQVNIKQKMQELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKR 770
P ++N KQ++ N ++ +Q + + ++E K ++ + +LL
Sbjct: 345 PSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQ-EHNNA 403
Query: 771 TLLIDELNKLKNEGPQR 787
I+EL + ++E R
Sbjct: 404 LKTIEELTRKESEKVDR 420
>gi|20149572 optineurin [Homo sapiens]
Length = 577
Score = 44.3 bits (103), Expect = 7e-04
Identities = 84/437 (19%), Positives = 177/437 (40%), Gaps = 54/437 (12%)
Query: 381 CQEHSKESPARSTPHRTPIIT-PNTKAIQ-ERLFKQDTSSSTTHLAQQLKQERQKELACL 438
C ++SP+ ST + P + PN E L +Q T + QLK+ + +
Sbjct: 8 CLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTEN--HQLKEAMKLNNQAM 65
Query: 439 RGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIP 498
+GRF++ + W+ KQ E +Q QS K+ ++ + E++ + +
Sbjct: 66 KGRFEELSAWT--------EKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGK 117
Query: 499 AKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDD 558
++ SS +P + ++ K L ++ V + + ++ E+++
Sbjct: 118 SERSSEDPTDDSRLPRAEAEQEKDQL-----RTQVVRLQAEKADLLGIVSELQLK----- 167
Query: 559 INSSKVINDLFSDV-LEEGELDMEKSQEEMDQ------------ALAESSEEQEDA---- 601
+NSS D F ++ + EGE E S +E+ AL++ D
Sbjct: 168 LNSSGSSEDSFVEIRMAEGEA--EGSVKEIKHSPGPTRTVSTGTALSKYRSRSADGAKNY 225
Query: 602 -----LNISSMSLLA----PLAQTVGVVSPESLVSTPRLELKDTSRSD-ESPKPGKFQRT 651
L +S + L + + V E+ E K ++RS+ E+ G ++
Sbjct: 226 FEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKE 285
Query: 652 RVPRAESGDSLGSEDRDLLYSIDA-YRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAF 710
+ +++GSE L + + ++ + T+ + + R ++ L+ KN+A
Sbjct: 286 N-DEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAI 344
Query: 711 PCQVNIKQKMQELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKR 770
P ++N KQ++ N ++ +Q + + ++E K ++ + +LL
Sbjct: 345 PSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQ-EHNNA 403
Query: 771 TLLIDELNKLKNEGPQR 787
I+EL + ++E R
Sbjct: 404 LKTIEELTRKESEKVDR 420
>gi|56549107 optineurin [Homo sapiens]
Length = 577
Score = 44.3 bits (103), Expect = 7e-04
Identities = 84/437 (19%), Positives = 177/437 (40%), Gaps = 54/437 (12%)
Query: 381 CQEHSKESPARSTPHRTPIIT-PNTKAIQ-ERLFKQDTSSSTTHLAQQLKQERQKELACL 438
C ++SP+ ST + P + PN E L +Q T + QLK+ + +
Sbjct: 8 CLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTEN--HQLKEAMKLNNQAM 65
Query: 439 RGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIP 498
+GRF++ + W+ KQ E +Q QS K+ ++ + E++ + +
Sbjct: 66 KGRFEELSAWT--------EKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGK 117
Query: 499 AKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDD 558
++ SS +P + ++ K L ++ V + + ++ E+++
Sbjct: 118 SERSSEDPTDDSRLPRAEAEQEKDQL-----RTQVVRLQAEKADLLGIVSELQLK----- 167
Query: 559 INSSKVINDLFSDV-LEEGELDMEKSQEEMDQ------------ALAESSEEQEDA---- 601
+NSS D F ++ + EGE E S +E+ AL++ D
Sbjct: 168 LNSSGSSEDSFVEIRMAEGEA--EGSVKEIKHSPGPTRTVSTGTALSKYRSRSADGAKNY 225
Query: 602 -----LNISSMSLLA----PLAQTVGVVSPESLVSTPRLELKDTSRSD-ESPKPGKFQRT 651
L +S + L + + V E+ E K ++RS+ E+ G ++
Sbjct: 226 FEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKE 285
Query: 652 RVPRAESGDSLGSEDRDLLYSIDA-YRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAF 710
+ +++GSE L + + ++ + T+ + + R ++ L+ KN+A
Sbjct: 286 N-DEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAI 344
Query: 711 PCQVNIKQKMQELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKR 770
P ++N KQ++ N ++ +Q + + ++E K ++ + +LL
Sbjct: 345 PSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQ-EHNNA 403
Query: 771 TLLIDELNKLKNEGPQR 787
I+EL + ++E R
Sbjct: 404 LKTIEELTRKESEKVDR 420
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 44.3 bits (103), Expect = 7e-04
Identities = 94/407 (23%), Positives = 151/407 (37%), Gaps = 48/407 (11%)
Query: 28 TAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQP 87
T A S T + P+S S PL S T + + T V+ + P
Sbjct: 782 TEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVD-----SNSP 836
Query: 88 VESTSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQ 147
V +++ S SP+P P + T S+ S+ +++ L AT+A + T
Sbjct: 837 VTTSTEVSSSPTPAEGTSMPTS--TYSEGRTPLTSM-----PVSTTLVATSA--ISTLST 887
Query: 148 KLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRGRLANLAA 207
+ N P +S + MP+ PL S +T L+A
Sbjct: 888 TPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGST-PLTSMPDSTTPVVSSEARTLSA 946
Query: 208 TICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDA 267
T V S +S GT+ + S+ S + + S+ V S+
Sbjct: 947 TPVDTSTPVTTSTEATSSPTTAEGTSIPT--STPSEGTTPLTSTPVSHTLVANSEAS--- 1001
Query: 268 SLNKALSSSADDASLVNASISSSVKATSPVKST--TSITDAKSCEGQNPELLPKTPISPL 325
LS++ D+ N +++S +A+SP + TS+ + EG P L + P+S
Sbjct: 1002 ----TLSTTPVDS---NTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTP--LTRMPVSTT 1052
Query: 326 KTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGGTGIKPFLERFGE------ 379
S+ STLS T + S + SQ+ STT GT + G
Sbjct: 1053 MVASSE---TSTLSTT---PADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSV 1106
Query: 380 ----RCQEHSKESPARSTPHRTPI-ITPNTKAIQERLFKQDTSSSTT 421
R S+ S +TP T I +T +T+A + TS T+
Sbjct: 1107 PVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTS 1153
Score = 38.9 bits (89), Expect = 0.028
Identities = 67/323 (20%), Positives = 125/323 (38%), Gaps = 33/323 (10%)
Query: 62 TKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQPQAA-------DTIS 114
T + S + CS T E +++ N P E T+ + P +P V +A+ DT +
Sbjct: 1366 TPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTST 1425
Query: 115 DSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMT--DDIPESSLFS 172
+ + + S KT ++ + N + + P S S
Sbjct: 1426 PGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSN-S 1484
Query: 173 PMPSEEKAASPPRPL--LSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQP 230
P+ + +S P P S A +TP L ++ + + +S + +V P
Sbjct: 1485 PVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTP 1544
Query: 231 GTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSS 290
T +S AS + + +S+ Q +T+ +G L +S ++++ S ++
Sbjct: 1545 VTT----YSQASSSPTTADGTSM-QTSTYS---EGSTPL-----TSLPVSTMLVVSSEAN 1591
Query: 291 VKATSPVKSTTSIT------DAKSCEGQNPELLPKTPISPLKTG--VSKPIVKSTLSQTV 342
+T+P+ S T +T + + EG + + + SPL T VS V S + T+
Sbjct: 1592 TLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTL 1651
Query: 343 PSKGELSREICLQSQSKDKSTTP 365
+ S + S S TP
Sbjct: 1652 STTPVDSNSPVITSTEVSSSPTP 1674
Score = 34.3 bits (77), Expect = 0.68
Identities = 83/403 (20%), Positives = 138/403 (34%), Gaps = 70/403 (17%)
Query: 285 ASISSSVKATSPVKSTTSITDAKSCEGQNPEL----LP-------KTPISPLKTGVSKPI 333
AS +S +T+PV S T +T + P +P TP++ + + P+
Sbjct: 465 ASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVS-TMPV 523
Query: 334 VKSTLSQTVPSKGELSREICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARST 393
S S + + S + S++ STTP GT I G +P +
Sbjct: 524 ASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEG--------STPLTNM 575
Query: 394 PHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKG 453
P T ++ + T+ + ++ E G + +S E+G
Sbjct: 576 PVSTRLV------VSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYS-ERG 628
Query: 454 GNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECE 513
S + T +++ L S T TE T + A+ +S +TE
Sbjct: 629 TTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTE-ATSSSTTAEGTSMPTSTYTEGS 687
Query: 514 MTKSS-PLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDINSSKVINDLFSDV 572
+S P+ TL + S S V+ V E S
Sbjct: 688 TPLTSMPVNTTLVASSEAS--TLSTTPVDTSTPVTTSTEAS------------------- 726
Query: 573 LEEGELDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPESLVSTPRLE 632
S D A +S E + ++SM P+++T+ S S +ST L+
Sbjct: 727 ---------SSPTTADGASMPTSTPSEGSTPLTSM----PVSKTLLTSSEASTLSTTPLD 773
Query: 633 LKD--TSRSDESPKPGKFQRTRVPRAESGDSLGSEDRDLLYSI 673
T+ ++ S P + T +P S SE LL SI
Sbjct: 774 TSTHITTSTEASCSPTTTEGTSMP-----ISTPSEGSPLLTSI 811
Score = 31.6 bits (70), Expect = 4.4
Identities = 78/385 (20%), Positives = 134/385 (34%), Gaps = 47/385 (12%)
Query: 52 PLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPS-----------P 100
PL+ E S + P+ +T E S PV +T+ S S P
Sbjct: 3252 PLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTP 3311
Query: 101 VSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDD 160
V+ Q ++ I+D ++P S + + + V + L+ D
Sbjct: 3312 VTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLS--TTPVDTST 3369
Query: 161 MTDDIPESSLFSPMPSEEKA--ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNH 218
E+SL SP +E + S P + ++ PV +++ T+ + D N
Sbjct: 3370 PVTTSTEASL-SPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNT 3428
Query: 219 SFAKQNSVQEQP----GTACLSKFSSASGASARINSSS----VKQEATFCSQRDGDASLN 270
P GT+ + +S I S EA+ S D S
Sbjct: 3429 LVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTS-T 3487
Query: 271 KALSSSADDASLVNASISSSVKATSPVKST------TSITDAKSCEGQNPELLP---KTP 321
+SS ++S A ++S +T+ ST S T S E P T
Sbjct: 3488 PVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTF 3547
Query: 322 ISPLKTGVSKP--IVKSTLSQTVPSKGELSREICLQSQ---SKDKSTTPGGTGIKPFLER 376
++ S P + +T+ + PS+G S L S + +++TP +
Sbjct: 3548 VTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSV------ 3601
Query: 377 FGERCQEHSKESPARSTPHRTPIIT 401
+R + + + STP +IT
Sbjct: 3602 --DRSTPVTTSTQSNSTPTPPEVIT 3624
>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo
sapiens]
Length = 2365
Score = 44.3 bits (103), Expect = 7e-04
Identities = 87/424 (20%), Positives = 155/424 (36%), Gaps = 60/424 (14%)
Query: 2 DPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSC 61
+P + RA R+N + A+R S A R S A P +
Sbjct: 509 NPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRA------- 561
Query: 62 TKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQ-PQAADTISDSVAV- 119
++ S + DN + +N + A +P+ Q P+A+ T S + A
Sbjct: 562 SRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATR 621
Query: 120 --PASLLGMRRG--LNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMP 175
P + R +S T S +T + + R N + + P +S +
Sbjct: 622 DNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSC--ALR 679
Query: 176 SEEKAASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACL 235
+A+SP R + T C+ DD S + + QE P T+C
Sbjct: 680 DNPRASSPSRTIQQENPRTS--------------CAQRDDPRASSPNRTTQQENPRTSCA 725
Query: 236 SKFSSASGASARINSSSVKQEATFCSQRDGD--ASLNKAL----------------SSSA 277
+ + AS+R + T C+QRD +S N+ + +SS
Sbjct: 726 RRDNPR--ASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSP 783
Query: 278 DDASLVNASIS----SSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPI 333
+ A+ N S +++A+SP+++T + ++C QN T KT +K
Sbjct: 784 NRATRDNPRTSCAQRDNLRASSPIRATQQ-DNPRTCIQQNIPRSSSTQQDNPKTSCTK-- 840
Query: 334 VKSTLSQTVPSKGELSREICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARST 393
+ L T + + ++ Q + S++ T + R + + +P S+
Sbjct: 841 -RDNLRPTCTQR-DRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWN--NPRNSS 896
Query: 394 PHRT 397
PHRT
Sbjct: 897 PHRT 900
Score = 37.7 bits (86), Expect = 0.062
Identities = 52/281 (18%), Positives = 109/281 (38%), Gaps = 31/281 (11%)
Query: 38 KRARQPLSEASNQQPLSGGEEKSCTKPSPSKK---RCSDNTEVEVSNLENKQPVESTSAK 94
+R R L++AS+ P SG + ++ SP+++ + + E+ ++ ++ TS
Sbjct: 234 ERHRSTLTQASSMTPHSG-PRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRA 292
Query: 95 SCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRR 154
S + +S +A+ T ++ ++ R +++ + ASS +
Sbjct: 293 SSTQQEIS-----RASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQ----------- 336
Query: 155 RWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRGRLANLAATICSWED 214
W+ + + L +P S + +P S + TP R T C +D
Sbjct: 337 -WNTPRASSPSRSTQLDNPRTSSTQQDNPQT---SFPTCTPQRENPR------TPCVQQD 386
Query: 215 DVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGD-ASLNKAL 273
D S + + +E T+C + + + ++ N ++ T C+QRD AS
Sbjct: 387 DPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRA 446
Query: 274 SSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNP 314
+ S + + +SP ++T + NP
Sbjct: 447 TRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNP 487
Score = 37.4 bits (85), Expect = 0.081
Identities = 65/322 (20%), Positives = 118/322 (36%), Gaps = 33/322 (10%)
Query: 7 KLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQP----LSGGEEKSCT 62
++ +R +R + Q++++ R ++ + + A ++ AS+ Q S + +
Sbjct: 283 RITQRDTSRASSTQQEIS-RASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPR 341
Query: 63 KPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQPQAADTISDSVAVPAS 122
SPS+ DN + +N Q TS +C+P +P+ D D A +
Sbjct: 342 ASSPSRSTQLDNPRTSSTQQDNPQ----TSFPTCTPQRENPRTPCVQQD---DPRASSPN 394
Query: 123 LLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLF---SPMPSEEK 179
R NSR + K R + T D P +S +P S
Sbjct: 395 RTTQRE--NSRTSCAQRDNPKAS--------RTSSPNRATRDNPRTSCAQRDNPRASSPS 444
Query: 180 AASPPRPLLSNASA-TPVGRRGRLANLAA-----TICSWEDDVNHSFAKQNSVQEQPGTA 233
A+ P S A P R N A T C+ D+ S + + ++ P T+
Sbjct: 445 RATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRAS-SPSRATRDNPTTS 503
Query: 234 CLSKFSSASGASARINSSSVKQEATFCSQRDGD-ASLNKALSSSADDASLVNASISSSVK 292
C + + + ++ N ++ T C+QRD AS + S + +
Sbjct: 504 CAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASR 563
Query: 293 ATSPVKSTTSITDAKSCEGQNP 314
+SP ++T + NP
Sbjct: 564 TSSPNRATRDNPRTSCAQRDNP 585
Score = 35.8 bits (81), Expect = 0.23
Identities = 66/328 (20%), Positives = 119/328 (36%), Gaps = 34/328 (10%)
Query: 2 DPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSC 61
+P + RA R+N + A+R S + A R S A P
Sbjct: 411 NPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNP-------RA 463
Query: 62 TKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQ---PQAADTISDSVA 118
++ S + DN + +N P S+ +++ +P + Q P+A+ T S + A
Sbjct: 464 SRTSSPNRATRDNPRTSCAQRDN--PRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRA 521
Query: 119 V---PASLLGMR---RGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLF- 171
P + R R + A + + R + T D P +S
Sbjct: 522 TRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQ 581
Query: 172 --SPMPSEEKAASPPRPLLSNASA-TPVGRRGRLANLAA-----TICSWEDDVNHSFAKQ 223
+P S A+ P S A P R N A T C+ D+ S +
Sbjct: 582 RDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNR 641
Query: 224 NSVQEQPGTACLSKFSSASGASARINSSSVKQE--ATFCSQRDGDASLNKALSSSADDAS 281
+ Q+ P T+C + + + R +++QE T C+ RD + + + + ++
Sbjct: 642 TTQQDSPRTSCARRDDPRASSPNR----TIQQENPRTSCALRDNPRASSPSRTIQQENPR 697
Query: 282 LVNASISSSVKATSPVKSTTSITDAKSC 309
+ + +A+SP ++T SC
Sbjct: 698 -TSCAQRDDPRASSPNRTTQQENPRTSC 724
Score = 31.2 bits (69), Expect = 5.8
Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 7/100 (7%)
Query: 21 RKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVS 80
R ER R + A A Q E +QQP G + + SP+ R +V+
Sbjct: 1304 RAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSR-------QVT 1356
Query: 81 NLENKQPVESTSAKSCSPSPVSPQVQPQAADTISDSVAVP 120
L KQ + +++ P P SP+ +P+ + S P
Sbjct: 1357 MLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLPP 1396
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 43.1 bits (100), Expect = 0.001
Identities = 117/589 (19%), Positives = 214/589 (36%), Gaps = 96/589 (16%)
Query: 10 ERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKK 69
ERT + AE R+ + +E + + + E + + P++
Sbjct: 466 ERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTEN 525
Query: 70 R-CSDNTEVEVSNLENKQPVESTSAKSCSPSPVSP----QVQPQAADTISDSVAVPASLL 124
R + N + +S +E + E+T+ + +PSP P Q P A + + S A P
Sbjct: 526 RETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEH- 584
Query: 125 GMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPP 184
G R L + E T S + E R R N+ T P P+E
Sbjct: 585 GERTPLAN--ENTTPSPAEP-----TENRERTANEKTT----------PSPAEPTENGDR 627
Query: 185 RPLLSN------ASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKF 238
PL + A T G+R AN T S E + + T ++
Sbjct: 628 TPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEP-----------TEHEERTPLANEN 676
Query: 239 SSASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVK 298
++ S A N E T S + N+ ++++ + +L A + + + T+ K
Sbjct: 677 TTPSPAEPTENRERTANENTTPSP--AGPTENREMTAN-EKTTLFPAEPTENRERTANEK 733
Query: 299 STTSITDAKSCEGQNPELLPKTPIS---PLKTGVSKPIVK--STLSQTVPSKGELSREIC 353
+T+S + + P KT S P + G P+ +TLS P++
Sbjct: 734 TTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTEN------- 786
Query: 354 LQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPH--RTPIITPNTKAIQERL 411
+ ++ ++ TTP ER E++ SPA+ T + RTP+ T
Sbjct: 787 -RERTANEKTTPFPAEPTENRER---TANENTTPSPAQPTENGDRTPLANEKT------- 835
Query: 412 FKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQS 471
T LA+ + ++ A +K SAE +++ L + T +
Sbjct: 836 --------TPSLAEPTENGKRTPFAN-----EKTTSSSAEPTEHAERTPLANENTTSSPA 882
Query: 472 TPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEP--------KGFTECEMTKSSPLKIT 523
P + + + ++ + TEN+ N T P + +T E T SP + T
Sbjct: 883 EPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPT 942
Query: 524 -------LFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDINSSKVI 565
L ++E+ E+ ++ + + + +S++I
Sbjct: 943 EHEEMTPLMVDENLQAPFRQGSCAERPKDICATVASTTGSESSTASEII 991
Score = 38.9 bits (89), Expect = 0.028
Identities = 112/546 (20%), Positives = 194/546 (35%), Gaps = 84/546 (15%)
Query: 22 KMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSN 81
K+ + T + A Q L+E + + E + + P++ R + T E +
Sbjct: 322 KLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENR--ERTANENTT 379
Query: 82 LENKQPVES---TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATA 138
L +P E+ T+ ++ +P P P + + ++ PA E TA
Sbjct: 380 LSPAEPTENRERTANENTAPFPAGP-TENREMTANENTTLFPAEP-------TEHGERTA 431
Query: 139 ASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASP---PRPLLSNASATP 195
+ + E R N++ T E P+E +P + S+A +T
Sbjct: 432 NENTTPSPAEPTEHGERTANENTTPSPAE-------PTEHGERTPFANDKTTSSSAESTE 484
Query: 196 VGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASG------------ 243
G R LAN T E N + P ++ ++A+
Sbjct: 485 HGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTEN 544
Query: 244 --ASARINSSSVKQEATFCSQRDGDASLNKALSSSADDAS------LVNASISSSV---- 291
+A ++ E T QR A+ K SSSA+ L N + + S
Sbjct: 545 RETTANEKTTPSPAEPTENGQRTPFAN-EKTTSSSAEPTEHGERTPLANENTTPSPAEPT 603
Query: 292 ---KATSPVKSTTSITDAKSCEGQNPELLPKTPIS---PLKTGVSKPIV--KSTLSQTVP 343
+ T+ K+T S + + P KT S P + G P K+T S P
Sbjct: 604 ENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEP 663
Query: 344 SKGELSREICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPN 403
++ E + +++TTP ER E++ SPA T +R +T N
Sbjct: 664 TEHEERTPLA------NENTTPSPAEPTENRER---TANENTTPSPAGPTENRE--MTAN 712
Query: 404 TKAI---------QERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGG 454
K +ER + T+SS A+ + ++ A +K SAE
Sbjct: 713 EKTTLFPAEPTENRERTANEKTTSSP---AEPTENGQRTPFAN-----EKTTSSSAEPTE 764
Query: 455 NSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEM 514
+ + L + T + P + + + ++ P + TEN+ N +T P E
Sbjct: 765 HGERTPLANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTEN 824
Query: 515 TKSSPL 520
+PL
Sbjct: 825 GDRTPL 830
Score = 32.3 bits (72), Expect = 2.6
Identities = 61/295 (20%), Positives = 99/295 (33%), Gaps = 46/295 (15%)
Query: 249 NSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAKS 308
NSS+ ++ +QR D + + + + + S + +++T
Sbjct: 186 NSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSD 245
Query: 309 CEGQNPE----LLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKST- 363
G+ E L KT S KT S S SQT +I S++ K+T
Sbjct: 246 KTGRPLEKSMSTLDKTSTSSHKTTTS--FHNSGNSQTKQKSTSFPEKITAASKTTYKTTG 303
Query: 364 TPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHL 423
TP +E K +R+T ++T TK IQE + S L
Sbjct: 304 TP----------------EESEKTEDSRTTVASDKLLTKTTKNIQETI-------SANEL 340
Query: 424 AQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKT 483
Q L + + G + E S ++ E ++ T ++T L +
Sbjct: 341 TQSLAEPT-----------EHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPTENR 389
Query: 484 QSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDP 538
+ EN P TE + T E T P + T E + T P
Sbjct: 390 E-----RTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSP 439
>gi|238624188 diffuse panbronchiolitis critical region 1 protein
[Homo sapiens]
Length = 1393
Score = 42.7 bits (99), Expect = 0.002
Identities = 112/540 (20%), Positives = 197/540 (36%), Gaps = 89/540 (16%)
Query: 10 ERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKK 69
ERT + AE R+ + +E + + + E + + P++
Sbjct: 404 ERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTEN 463
Query: 70 R-CSDNTEVEVSNLENKQPVESTSAKSCSPSPVSP----QVQPQAADTISDSVAVPASLL 124
R + N + +S +E + E+T+ + +PSP P Q P A + + S A P
Sbjct: 464 RETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEH- 522
Query: 125 GMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPP 184
G R L + E T S + E R R N+ T P P+E
Sbjct: 523 GERTPLAN--ENTTPSPAEP-----TENRERTANEKTT----------PSPAEPTENGDR 565
Query: 185 RPLLSN------ASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKF 238
PL + A T G+R AN T S E + + T ++
Sbjct: 566 TPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEP-----------TEHEERTPLANEN 614
Query: 239 SSASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVK 298
++ S A N E T S + N+ ++++ + +L A + + + T+ K
Sbjct: 615 TTPSPAEPTENRERTANENTTPSP--AGPTENREMTAN-EKTTLFPAEPTENRERTANEK 671
Query: 299 STTSITDAKSCEGQNPELLPKTPIS---PLKTGVSKPIVK--STLSQTVPSKGELSREIC 353
+T+S + + P KT S P + G P+ +TLS P++
Sbjct: 672 TTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTEN------- 724
Query: 354 LQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPH--RTPIITPNTKAIQERL 411
+ ++ ++ TTP ER E++ SPA+ T + RTP+ T
Sbjct: 725 -RERTANEKTTPFPAEPTENRER---TANENTTPSPAQPTENGDRTPLANEKT------- 773
Query: 412 FKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQS 471
T LA+ + ++ A +K SAE +++ L + T +
Sbjct: 774 --------TPSLAEPTENGKRTPFAN-----EKTTSSSAEPTEHAERTPLANENTTSSPA 820
Query: 472 TPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEP--------KGFTECEMTKSSPLKIT 523
P + + + ++ + TEN+ N T P + +T E T SP + T
Sbjct: 821 EPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPT 880
Score = 40.4 bits (93), Expect = 0.010
Identities = 112/546 (20%), Positives = 195/546 (35%), Gaps = 84/546 (15%)
Query: 22 KMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSN 81
K+ + T + A Q L+E + + E + + P++ R + T E +
Sbjct: 260 KLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENR--ERTANENTT 317
Query: 82 LENKQPVES---TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATA 138
L +P+E+ T+ ++ +P P P + + ++ PA E TA
Sbjct: 318 LSPAEPIENRERTANENTAPFPAGP-TENREMTANENTTLFPAEP-------TEHGERTA 369
Query: 139 ASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASP---PRPLLSNASATP 195
+ + E R N++ T E P+E +P + S+A +T
Sbjct: 370 NENTTPSPAEPTEHGERTANENTTPSPAE-------PTEHGERTPFANDKTTSSSAESTE 422
Query: 196 VGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASG------------ 243
G R LAN T E N + P ++ ++A+
Sbjct: 423 HGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTEN 482
Query: 244 --ASARINSSSVKQEATFCSQRDGDASLNKALSSSADDAS------LVNASISSSV---- 291
+A ++ E T QR A+ K SSSA+ L N + + S
Sbjct: 483 RETTANEKTTPSPAEPTENGQRTPFAN-EKTTSSSAEPTEHGERTPLANENTTPSPAEPT 541
Query: 292 ---KATSPVKSTTSITDAKSCEGQNPELLPKTPIS---PLKTGVSKPIV--KSTLSQTVP 343
+ T+ K+T S + + P KT S P + G P K+T S P
Sbjct: 542 ENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEP 601
Query: 344 SKGELSREICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPN 403
++ E + +++TTP ER E++ SPA T +R +T N
Sbjct: 602 TEHEERTPLA------NENTTPSPAEPTENRER---TANENTTPSPAGPTENRE--MTAN 650
Query: 404 TKAI---------QERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGG 454
K +ER + T+SS A+ + ++ A +K SAE
Sbjct: 651 EKTTLFPAEPTENRERTANEKTTSSP---AEPTENGQRTPFAN-----EKTTSSSAEPTE 702
Query: 455 NSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEM 514
+ + L + T + P + + + ++ P + TEN+ N +T P E
Sbjct: 703 HGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTEN 762
Query: 515 TKSSPL 520
+PL
Sbjct: 763 GDRTPL 768
Score = 32.7 bits (73), Expect = 2.0
Identities = 60/291 (20%), Positives = 107/291 (36%), Gaps = 41/291 (14%)
Query: 44 LSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSP----- 98
++ S +P GE + K +PS + +++ E V+ E T +P
Sbjct: 934 ITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANEN 993
Query: 99 SPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDN 158
+ SP + + ++ P+ G E T +++ KT + + ++
Sbjct: 994 TTTSPTESTEHGERTANEKTTPSPAEPTEHG-----ERTPSANEKT----IPSPAKPTEH 1044
Query: 159 DDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNH 218
++MT P +E SP +P T G + LAN T+ S E H
Sbjct: 1045 EEMT----------PSANENTTPSPVKP-------TEHGEKTTLANEKITL-SPEGPTEH 1086
Query: 219 SFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLNKALSSSAD 278
AK S E+ T L+K + + N A RD S N + A+
Sbjct: 1087 G-AKTTSANEKI-TPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANVITPAPAE 1144
Query: 279 D------ASLVNASISS-SVKATSPVKSTTSITDAKSCEGQNPELLPKTPI 322
+L + ++ + K+T + TTS T+ + + P L + I
Sbjct: 1145 PIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTI 1195
Score = 31.2 bits (69), Expect = 5.8
Identities = 65/339 (19%), Positives = 126/339 (37%), Gaps = 28/339 (8%)
Query: 221 AKQNSVQEQPGTACLSKFSSASG-----ASARINSSSVKQEATFCSQRDGDASLNKALSS 275
+K N + G + +++ S +G + + ++ +S T S + S K S+
Sbjct: 164 SKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKST 223
Query: 276 SADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVK 335
S + + A+ ++ K T + + D+++ + +LL KT + +T +S +
Sbjct: 224 SFPEK--ITAASKTTYKTTGTPEESEKTEDSRTTVASD-KLLTKTTKNIQET-ISANELT 279
Query: 336 STLSQTVPSKGELSREICLQSQSKD----KSTTPGGTGIKPF--LERFGERCQEHSKESP 389
+L++ G + E S ++ + T T + P +E E++ P
Sbjct: 280 QSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFP 339
Query: 390 ARSTPHRTPIITPNTKAIQ-------ERLFKQDTSSSTTHLAQQLKQERQKELACLRGRF 442
A T +R NT ER ++T+ S + ER
Sbjct: 340 AGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEH--GERTANENTTPSPA 397
Query: 443 DKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEK---VTENQIPA 499
+ N K+ + H + TPL ++ + + + P + EN P+
Sbjct: 398 EPTEHGERTPFANDKTTSSSAESTEHGERTPLA-NENTTPSPAEPTENRERTANENTTPS 456
Query: 500 KNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDP 538
TE + T E T SP++ T E + K T P
Sbjct: 457 PAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSP 495
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,419,250
Number of Sequences: 37866
Number of extensions: 1984143
Number of successful extensions: 9263
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 352
Number of HSP's that attempted gapping in prelim test: 8143
Number of HSP's gapped (non-prelim): 1262
length of query: 1124
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1011
effective length of database: 13,968,660
effective search space: 14122315260
effective search space used: 14122315260
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.