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Search of human proteins with 31581524
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31581524 cordon-bleu homolog [Homo sapiens]
(1261 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31581524 cordon-bleu homolog [Homo sapiens] 2535 0.0
gi|62821787 COBL-like 1 [Homo sapiens] 232 1e-60
gi|116268091 PHD finger protein 23 [Homo sapiens] 46 3e-04
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 45 4e-04
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 45 4e-04
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 45 6e-04
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 45 6e-04
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 45 6e-04
gi|30039694 zinc finger protein 598 [Homo sapiens] 45 6e-04
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 44 7e-04
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 44 7e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 44 7e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 44 0.001
gi|217035133 hypothetical protein LOC55765 isoform 2 [Homo sapiens] 44 0.001
gi|217035131 hypothetical protein LOC55765 isoform 1 [Homo sapiens] 44 0.001
gi|50428935 BPY2 interacting protein 1 [Homo sapiens] 44 0.001
gi|157168329 formin 1 [Homo sapiens] 43 0.002
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int... 43 0.002
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 43 0.002
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 42 0.003
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 42 0.003
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 42 0.003
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 42 0.003
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 42 0.003
gi|52485606 formin-like 2 [Homo sapiens] 42 0.004
gi|112789555 ADAM metallopeptidase with thrombospondin type 1 mo... 42 0.004
gi|46094081 development and differentiation enhancing factor 1 [... 42 0.005
gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Hom... 42 0.005
gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo... 42 0.005
gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens] 41 0.006
>gi|31581524 cordon-bleu homolog [Homo sapiens]
Length = 1261
Score = 2535 bits (6571), Expect = 0.0
Identities = 1261/1261 (100%), Positives = 1261/1261 (100%)
Query: 1 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 60
MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA
Sbjct: 1 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 60
Query: 61 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 120
STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP
Sbjct: 61 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 120
Query: 121 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 180
NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI
Sbjct: 121 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 180
Query: 181 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE 240
LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE
Sbjct: 181 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE 240
Query: 241 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKR 300
TDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKR
Sbjct: 241 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKR 300
Query: 301 RAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEEN 360
RAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEEN
Sbjct: 301 RAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEEN 360
Query: 361 RKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLD 420
RKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLD
Sbjct: 361 RKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLD 420
Query: 421 SQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDE 480
SQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDE
Sbjct: 421 SQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDE 480
Query: 481 EDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIP 540
EDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIP
Sbjct: 481 EDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIP 540
Query: 541 VTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPAL 600
VTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPAL
Sbjct: 541 VTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPAL 600
Query: 601 HPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERT 660
HPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERT
Sbjct: 601 HPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERT 660
Query: 661 QATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCY 720
QATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCY
Sbjct: 661 QATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCY 720
Query: 721 DRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHL 780
DRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHL
Sbjct: 721 DRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHL 780
Query: 781 GRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMG 840
GRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMG
Sbjct: 781 GRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMG 840
Query: 841 MGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKA 900
MGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKA
Sbjct: 841 MGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKA 900
Query: 901 PVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRK 960
PVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRK
Sbjct: 901 PVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRK 960
Query: 961 LSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTD 1020
LSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTD
Sbjct: 961 LSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTD 1020
Query: 1021 PPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNET 1080
PPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNET
Sbjct: 1021 PPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNET 1080
Query: 1081 DSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAK 1140
DSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAK
Sbjct: 1081 DSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAK 1140
Query: 1141 LSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGL 1200
LSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGL
Sbjct: 1141 LSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGL 1200
Query: 1201 LSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLL 1260
LSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLL
Sbjct: 1201 LSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLL 1260
Query: 1261 V 1261
V
Sbjct: 1261 V 1261
>gi|62821787 COBL-like 1 [Homo sapiens]
Length = 1166
Score = 232 bits (592), Expect = 1e-60
Identities = 300/1160 (25%), Positives = 481/1160 (41%), Gaps = 230/1160 (19%)
Query: 1 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 60
MD P RK KA+AP PP + V S A ++ KE +
Sbjct: 1 MDGRTPRPQDAPARRKPKAKAPLPPAETKYTDVSSAADSVESTAF-----IMEQKENMID 55
Query: 61 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 120
++++VVLP + K + ++GS MMDLL+ LC Q HLNPS + +++ S+E Q + FKP
Sbjct: 56 KDVELSVVLPGDIIKSTTVHGSKPMMDLLIFLCAQYHLNPSSYTIDLLSAE-QNHIKFKP 114
Query: 121 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 180
NT IG L V V LK K+ ++K KP P +PEK+VR+V+N+ +TQK +VRVSP LQ +
Sbjct: 115 NTPIGMLEVEKVILKPKMLDKK-KP-TPIIPEKTVRVVINFKKTQKTIVRVSPHASLQEL 172
Query: 181 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE 240
P+IC+KCE P H +LL+D + E L+L+KSLN+LG++ELYA D RE+ + S +
Sbjct: 173 APIICSKCEFDPLHTLLLKDYQSQEPLDLTKSLNDLGLRELYAMDVNRESCQISQNLDIM 232
Query: 241 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSP--SMHSRSLTLGPSLSLGSISGVSVKSEMK 298
+KE K F FF+ +K+ + + P +P + H + T ++S IS K
Sbjct: 233 KEKENKGFFSFFQRSKKKRDQ-TASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPK 291
Query: 299 KRRA--PPPPGSGPPVQDKA-------------------------SEKVSLGS------- 324
KRRA PP P S QD A + +V GS
Sbjct: 292 KRRAPLPPMPASQSVPQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMS 351
Query: 325 --QIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEENRKSTMV----SLPLGSGSHCSP 378
L++ KR+AP+PP PP S +EN + T + +P S S +
Sbjct: 352 AGNSSLRRTKRKAPSPPSKIPPHQS----------DENSRVTALQPVDGVPPDSASEAN- 400
Query: 379 DGAPQVLSEAEETVSVGSCFASEDTT----EDSGVMSSP----SDIVSLDSQQDSMKYKD 430
+P+ LS + ET G + T E++ V P + I SL S S Y
Sbjct: 401 --SPEELS-SPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISS-DYSL 456
Query: 431 KWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLL--IAGE 488
+ ++E+ S+ ++ P+ + + T+ T ND + L +GE
Sbjct: 457 EEIDEKEELSEVPKVEAENISPKSQDI--------PFVSTDIINTLKNDPDSALGNGSGE 508
Query: 489 FRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCP-------QDAMIPHGDTDAIPV 541
F + +EE +++ TD S ++ SN ++ P+ + +
Sbjct: 509 FSQ------NSMEEKQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVQNEI 562
Query: 542 TFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALH 601
E ++D + +G+ N G + + + + +A + +E A
Sbjct: 563 IVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERPSNSEAHETDTAISYKENHLA-- 620
Query: 602 PASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNL-NAKVKDKV--------- 651
AS + + + +KD ++T P SF NL ++KV++ V
Sbjct: 621 -ASSVPDQKLNQPSAEKTKDA-AIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNIST 678
Query: 652 -YGCADGE---------RTQATERVNSQ-------------------PVNEKDSNDKNAA 682
+ C + R+Q T ++S+ PV+ D N +
Sbjct: 679 QHSCLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASY 738
Query: 683 LAPTSWHQRGQNP--------GKSYRLKHGLTTYKIIPPKSEMRCYDRDVSLSTGAIKID 734
L +++ NP + Y K G+TTYKI+PPKS +D T K D
Sbjct: 739 LKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLE--ISKDWQSETIEYKDD 796
Query: 735 ELGNLVSPHATGIR----------IISLSSSVPEAESQPIGKVREFWRCNSVEKHLGRPS 784
+ HA G + I + S++ E+ +P+ ++ + N +H
Sbjct: 797 Q-----DMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKP--KPNLRTEH----- 844
Query: 785 ESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGHV 844
VP+ +P+ + + P+ P K G P + +
Sbjct: 845 ----------QVPSSVSSPDDAMVS---PLKPAPKMTRDTGTAPFAPNLEEINNILESKF 891
Query: 845 RVPAAHT---TEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAP 901
+ A++ FL+ Q+R S YV SA AK + A A + AE+
Sbjct: 892 KSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAER------D 945
Query: 902 VLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCV--TPPNNHGEDLAVGAPP---RGEVIG 956
+L +P T+ + PHS Q P V T + G+ A +PP V
Sbjct: 946 MLPSPEQTL-SPLSKMPHSVPQ--------PLVEKTDDDVIGQAPAEASPPPIAPKPVTI 996
Query: 957 PHRKLSTQD----------RPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEA 1006
P ++STQ+ RP + S F+L V +S FS K+ T S A
Sbjct: 997 PASQVSTQNLKTLKTFGAPRPYSSSGPSPFAL--------AVVKRSQSFS-KERTESPSA 1047
Query: 1007 SSASEPRRAPDGTDPPPPHT 1026
S+ +P P T+ H+
Sbjct: 1048 SALVQP---PANTEEGKTHS 1064
>gi|116268091 PHD finger protein 23 [Homo sapiens]
Length = 403
Score = 45.8 bits (107), Expect = 3e-04
Identities = 43/171 (25%), Positives = 68/171 (39%), Gaps = 31/171 (18%)
Query: 283 LSLGSISGVSVKSEMKKRRAPPPPGSG---------PPVQDKASEKVSLGSQIDLQKKKR 333
LS G +S K + K R+ P G+G P + ++ + L+K +R
Sbjct: 169 LSQGDLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAER 228
Query: 334 --RAPAPPPPQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSG---------------SHC 376
R P P PPQ PP E++EE + M ++ G +
Sbjct: 229 GDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATV 288
Query: 377 SPDGAPQVLSEAEETVSVGSCFASE--DTTEDSGVMSSPSDIVSLDSQQDS 425
P+G P SE++E VGS S+ D + G M + + ++S DS
Sbjct: 289 HPEGVPPADSESKE---VGSTETSQDGDASSSEGEMRVMDEDIMVESGDDS 336
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 45.1 bits (105), Expect = 4e-04
Identities = 69/293 (23%), Positives = 113/293 (38%), Gaps = 37/293 (12%)
Query: 221 LYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLG 280
L A+ + ++T K S G+ + +KE K KV K + + + S S+ L
Sbjct: 166 LSAFSDPKKT--KPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSS--SKELERE 221
Query: 281 PSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPP 340
+ S S + + K PPP + A ++ L S + P PPP
Sbjct: 222 QAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLEST-----SPKGGPPPPP 276
Query: 341 PQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFAS 400
P PP S P + + + K S GS +P +P+ S S F+
Sbjct: 277 PPPPRASSKRPATADSPKPSAKKQKKS--SSKGSRSAPGTSPR--------TSSSSSFSD 326
Query: 401 EDTTEDSGVMSSPSDIVSLDSQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEK 460
+ +D S+ + V +S+ K A + E+ + +D A Q SP
Sbjct: 327 KKPAKDKS--STRGEKVKAESEPREAKK----ALEVEESNSEDEASFKSESAQSSP---S 377
Query: 461 NGSENSHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDLEEMEDSYETDTSS 513
N S +S +S+D + + L + EDL+ E+S E D+SS
Sbjct: 378 NSSSSS--------DSSSDSDFEPSQNHSQGPLRSMVEDLQS-EESDEDDSSS 421
Score = 33.5 bits (75), Expect = 1.3
Identities = 49/221 (22%), Positives = 81/221 (36%), Gaps = 17/221 (7%)
Query: 1009 ASEPRRAPDGTDPPPPHTSDTQACSRELVNGSVR----APGHGEPSHPPGGSGTESHILL 1064
++ P+ P PPPP S + + + S + + G S PG S S
Sbjct: 265 STSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRS-APGTSPRTSSSSS 323
Query: 1065 EREEKPSV--FSTDGNETDSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGG 1122
++KP+ ST G + + P KK V + + S S E+ S+
Sbjct: 324 FSDKKPAKDKSSTRGEKVKAESEPR---EAKKALEVEESNSEDEASFKS---ESAQSSPS 377
Query: 1123 KDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRD 1182
+ + P S ++G +++ ++ A+ + RD
Sbjct: 378 NSSSSSDSSSDSDFEP---SQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRD 434
Query: 1183 AALSAQGSESPLLEDLGLLSPPAIPP-PPPPPSQALSAPRT 1222
+ LS SES D L S PP PPPP+ +S R+
Sbjct: 435 SRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRS 475
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 45.1 bits (105), Expect = 4e-04
Identities = 49/187 (26%), Positives = 72/187 (38%), Gaps = 8/187 (4%)
Query: 185 CAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKE 244
C C V + +RD+I ++ +SK +G + D T + + E D+
Sbjct: 2964 CTLCGVKYSARLSIRDHIFSKQ-HISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRI 3022
Query: 245 KKK--FLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRA 302
KK LG L + P+ + L P L G S+ +
Sbjct: 3023 KKASDVLGLTVQQPGMMDSSSLHGISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNT 3082
Query: 303 PPPPGSGP---PVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTE--DK 357
PPG+G P +S +SL S + P PPPP PPP S L +TE +K
Sbjct: 3083 LTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNK 3142
Query: 358 EENRKST 364
E +K T
Sbjct: 3143 ESEKKQT 3149
Score = 41.6 bits (96), Expect = 0.005
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 7/75 (9%)
Query: 303 PPPPGSGPPVQDKASEKVSLGS-------QIDLQKKKRRAPAPPPPQPPPPSPLIPNRTE 355
PPPP PP+ + S+G LQ P PPPP PPPP P P
Sbjct: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPS 2017
Query: 356 DKEENRKSTMVSLPL 370
+ + + LPL
Sbjct: 2018 APPQVQLPVSLDLPL 2032
Score = 34.3 bits (77), Expect = 0.77
Identities = 13/20 (65%), Positives = 15/20 (75%)
Query: 1203 PPAIPPPPPPPSQALSAPRT 1222
PP PPPPPPPS +LS +T
Sbjct: 3118 PPPPPPPPPPPSSSLSGQQT 3137
Score = 32.0 bits (71), Expect = 3.8
Identities = 16/45 (35%), Positives = 19/45 (42%)
Query: 338 PPPPQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPDGAP 382
PPPP PPPP P P + + VS PL + P P
Sbjct: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPP 2002
Score = 30.8 bits (68), Expect = 8.5
Identities = 12/18 (66%), Positives = 12/18 (66%)
Query: 1203 PPAIPPPPPPPSQALSAP 1220
PP PPPPPPP SAP
Sbjct: 2002 PPPPPPPPPPPPPPPSAP 2019
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 44.7 bits (104), Expect = 6e-04
Identities = 40/145 (27%), Positives = 58/145 (40%), Gaps = 13/145 (8%)
Query: 217 GIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSKGCLTTPNSPS-MHSR 275
G +Y DNR T +S + + L F +N + N + TP+ P +
Sbjct: 47 GFDGIYYGDNRFNTVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADK 106
Query: 276 SLTLGPSLSLGSISGVSVKSEMKKRR-------APPPPGSGPPVQDKASEKVSLGSQIDL 328
+T SL G++ S +++ + PPPPG P SE GS L
Sbjct: 107 EVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPG-GSP--L 163
Query: 329 QKKKRRAPAPPPP--QPPPPSPLIP 351
AP PPP +PPPP + P
Sbjct: 164 PSPPSTAPPPPPLLLEPPPPPSMAP 188
Score = 33.5 bits (75), Expect = 1.3
Identities = 15/28 (53%), Positives = 18/28 (64%)
Query: 1203 PPAIPPPPPPPSQALSAPRTASRFSTGT 1230
PP++ PPPPP +ALS P T S S T
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPT 210
Score = 32.0 bits (71), Expect = 3.8
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
Query: 295 SEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIP 351
S++ RAP P G ++ A LG ++ P P PP PPP PL P
Sbjct: 350 SQVYPDRAPEPDCPGE-LKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP 405
Score = 31.2 bits (69), Expect = 6.5
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 8/57 (14%)
Query: 303 PPPPGSGPP---VQDKASEKVSLGSQIDLQKKKRRAPAPP-----PPQPPPPSPLIP 351
PPPP PP V + S +L S PAPP PP PP P+P P
Sbjct: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPP 237
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 44.7 bits (104), Expect = 6e-04
Identities = 40/145 (27%), Positives = 58/145 (40%), Gaps = 13/145 (8%)
Query: 217 GIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSKGCLTTPNSPS-MHSR 275
G +Y DNR T +S + + L F +N + N + TP+ P +
Sbjct: 47 GFDGIYYGDNRFNTVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADK 106
Query: 276 SLTLGPSLSLGSISGVSVKSEMKKRR-------APPPPGSGPPVQDKASEKVSLGSQIDL 328
+T SL G++ S +++ + PPPPG P SE GS L
Sbjct: 107 EVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPG-GSP--L 163
Query: 329 QKKKRRAPAPPPP--QPPPPSPLIP 351
AP PPP +PPPP + P
Sbjct: 164 PSPPSTAPPPPPLLLEPPPPPSMAP 188
Score = 33.5 bits (75), Expect = 1.3
Identities = 15/28 (53%), Positives = 18/28 (64%)
Query: 1203 PPAIPPPPPPPSQALSAPRTASRFSTGT 1230
PP++ PPPPP +ALS P T S S T
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPT 210
Score = 32.0 bits (71), Expect = 3.8
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
Query: 295 SEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIP 351
S++ RAP P G ++ A LG ++ P P PP PPP PL P
Sbjct: 350 SQVYPDRAPEPDCPGE-LKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP 405
Score = 31.2 bits (69), Expect = 6.5
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 8/57 (14%)
Query: 303 PPPPGSGPP---VQDKASEKVSLGSQIDLQKKKRRAPAPP-----PPQPPPPSPLIP 351
PPPP PP V + S +L S PAPP PP PP P+P P
Sbjct: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPP 237
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 44.7 bits (104), Expect = 6e-04
Identities = 40/145 (27%), Positives = 58/145 (40%), Gaps = 13/145 (8%)
Query: 217 GIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSKGCLTTPNSPS-MHSR 275
G +Y DNR T +S + + L F +N + N + TP+ P +
Sbjct: 47 GFDGIYYGDNRFNTVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADK 106
Query: 276 SLTLGPSLSLGSISGVSVKSEMKKRR-------APPPPGSGPPVQDKASEKVSLGSQIDL 328
+T SL G++ S +++ + PPPPG P SE GS L
Sbjct: 107 EVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPG-GSP--L 163
Query: 329 QKKKRRAPAPPPP--QPPPPSPLIP 351
AP PPP +PPPP + P
Sbjct: 164 PSPPSTAPPPPPLLLEPPPPPSMAP 188
Score = 33.5 bits (75), Expect = 1.3
Identities = 15/28 (53%), Positives = 18/28 (64%)
Query: 1203 PPAIPPPPPPPSQALSAPRTASRFSTGT 1230
PP++ PPPPP +ALS P T S S T
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPT 210
Score = 32.0 bits (71), Expect = 3.8
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
Query: 295 SEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIP 351
S++ RAP P G ++ A LG ++ P P PP PPP PL P
Sbjct: 350 SQVYPDRAPEPDCPGE-LKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP 405
Score = 31.2 bits (69), Expect = 6.5
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 8/57 (14%)
Query: 303 PPPPGSGPP---VQDKASEKVSLGSQIDLQKKKRRAPAPP-----PPQPPPPSPLIP 351
PPPP PP V + S +L S PAPP PP PP P+P P
Sbjct: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPP 237
>gi|30039694 zinc finger protein 598 [Homo sapiens]
Length = 904
Score = 44.7 bits (104), Expect = 6e-04
Identities = 64/304 (21%), Positives = 112/304 (36%), Gaps = 41/304 (13%)
Query: 960 KLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAP--D 1017
K +DR A + + Q + R + G K+ +++ PRR+P
Sbjct: 337 KREEEDREVAAAVRASVAAQQQEEARRSEDQEEGGRPKKEEAAARGPEDPRGPRRSPRTQ 396
Query: 1018 GTDPPPPHTSDTQACSRELVN-------GSVRAPGHGEPSHPPGGSGTESHILLEREEKP 1070
G P P TS S+E + G V PG P P L+ E+ P
Sbjct: 397 GEGPGPKETSTNGPVSQEAFSVTGPAAPGCVGVPGALPPPSPK----------LKDEDFP 446
Query: 1071 SVFSTDGNETDSIWPPSIFGPKKKFK--------------PVVQRPVPKDTSLHSALMEA 1116
S+ ++ + + P G + P + VPK + ++L+ A
Sbjct: 447 SLSASTSSSCSTAATPGPVGLALPYAIPARGRSAFQEEDFPALVSSVPKPGTAPTSLVSA 506
Query: 1117 IHSAGGKDRLRK---TAEHTGEGRPAKLSYTEAEGERSA--LLAAIRGHSGTCSLRKVAS 1171
+S+ ++ + +A+ TG G+P + + + G R G +L+++ S
Sbjct: 507 WNSSSSSKKVAQPPLSAQATGSGQPTRKAGKGSRGGRKGGPPFTQEEEEDGGPALQELLS 566
Query: 1172 SASEELQSFRDAALSAQGSESPLLEDLGLLSPPAIPPPPPP---PSQALSAPRTASRFST 1228
+ S S Q S+ + +G P P PPP P AL AP + +
Sbjct: 567 TRPTGSVSSTLGLASIQPSKVGKKKKVGSEKPGTTLPQPPPATCPPGALQAPEAPASRAE 626
Query: 1229 GTLS 1232
G ++
Sbjct: 627 GPVA 630
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 44.3 bits (103), Expect = 7e-04
Identities = 67/286 (23%), Positives = 100/286 (34%), Gaps = 43/286 (15%)
Query: 783 PSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMG 842
P + P S P+QT + + Q P+ PQ +S+ + P + +QPP
Sbjct: 476 PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSS----QPPYSQQPSQPP----- 526
Query: 843 HVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAPV 902
H + PA + + Q+ T+ Q+ P+ +P A+ Y + P
Sbjct: 527 HQQSPAPYPS-------QQSTTQQH-----------PQSQPPYSQPQ--AQSPYQQQQPQ 566
Query: 903 LAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGED----LAVGAPPRGEVIGPH 958
AP + P S+ Q + PP +D A AP G
Sbjct: 567 QPAPSTLSQQAAYPQPQSQ-QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625
Query: 959 R--KLSTQDRPAAI-HRSSCFSLVQSSQRDRVSVGQS-CGFSGKQSTSSQEASSASEPRR 1014
LS Q RP+++ S + +S G S G S Q S A S P
Sbjct: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685
Query: 1015 APD-----GTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGG 1055
+P G P P + + A SR PG+ P PP G
Sbjct: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG 731
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 44.3 bits (103), Expect = 7e-04
Identities = 67/286 (23%), Positives = 100/286 (34%), Gaps = 43/286 (15%)
Query: 783 PSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMG 842
P + P S P+QT + + Q P+ PQ +S+ + P + +QPP
Sbjct: 476 PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSS----QPPYSQQPSQPP----- 526
Query: 843 HVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAPV 902
H + PA + + Q+ T+ Q+ P+ +P A+ Y + P
Sbjct: 527 HQQSPAPYPS-------QQSTTQQH-----------PQSQPPYSQPQ--AQSPYQQQQPQ 566
Query: 903 LAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGED----LAVGAPPRGEVIGPH 958
AP + P S+ Q + PP +D A AP G
Sbjct: 567 QPAPSTLSQQAAYPQPQSQ-QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625
Query: 959 R--KLSTQDRPAAI-HRSSCFSLVQSSQRDRVSVGQS-CGFSGKQSTSSQEASSASEPRR 1014
LS Q RP+++ S + +S G S G S Q S A S P
Sbjct: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685
Query: 1015 APD-----GTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGG 1055
+P G P P + + A SR PG+ P PP G
Sbjct: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG 731
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 44.3 bits (103), Expect = 7e-04
Identities = 73/284 (25%), Positives = 103/284 (36%), Gaps = 51/284 (17%)
Query: 781 GRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPP-TM 839
G P S R +P+ + S + P+P P+++ A +G P G + T
Sbjct: 663 GHPRHSHYRKDTHSPLDS------SVTKQVPRP--PERRRACQDGSVPRYSGSSSSTRTQ 714
Query: 840 GMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVR---PHGYAEKGY 896
G++R P++ + L TSS V P VH+D V PH G+
Sbjct: 715 ASGNLRPPSSGSLPSQDLLG---TSSATVT---------PAVHSDFVSGVSPHNAPSAGW 762
Query: 897 AGKAPVLAAPPVTVKDDRTSSPHSETQGWKDGA----QWPCVTPPNNHGEDLAVGAPPRG 952
AG A P + PH+ K GA + TP + L VG P +G
Sbjct: 763 AGDAGSRTCSPAPIP------PHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQG 816
Query: 953 EVIGPHRK-----------LSTQDRPAAIHRSSCFSLVQSSQRDRVSV---GQSCGFSGK 998
V GPHR Q P+ C + R R SCG +G
Sbjct: 817 AV-GPHRSHCCSQPGTQPAQEAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGS 875
Query: 999 --QSTSSQEASSASEPRRAPDGTDPPPPHTSDTQACSRELVNGS 1040
QST+ S E R P T P P++ ++ S GS
Sbjct: 876 SHQSTARGPGGSPQEGTRQPGPTPSPGPNSGASRRSSASQGAGS 919
Score = 31.2 bits (69), Expect = 6.5
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 9/93 (9%)
Query: 999 QSTSSQEASSASEPRRAPDGTDP--PPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGS 1056
Q + AS+++EP A +P PP H S+T + E +GS PG +P P
Sbjct: 1428 QEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKP--PGATM 1485
Query: 1057 GTESHILLE-----REEKPSVFSTDGNETDSIW 1084
+ H + E SV + + D IW
Sbjct: 1486 MGQEHTQAQPTQGAAERSSSVACSAALDCDPIW 1518
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 43.9 bits (102), Expect = 0.001
Identities = 60/330 (18%), Positives = 131/330 (39%), Gaps = 13/330 (3%)
Query: 354 TEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSP 413
+ D + + S S S S D + S+++ + S S+ ++ S SS
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD 649
Query: 414 SDIVSLDSQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKA 473
S S DS S ++D D SD + S + + S NS ++ +
Sbjct: 650 SSDNS-DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS---DSSDSSNSSESSDSS 705
Query: 474 VTASNDEEDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPH 533
++ +D D + + ++ + + S +D+S + S + + + D+
Sbjct: 706 DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765
Query: 534 GDTDAIPVTFIGEVSD--DPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHE 591
+D+ + + S+ D DS S+ ++++ S DS + DS ++ S +
Sbjct: 766 DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825
Query: 592 KAREEVPALHPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKV 651
+ S D + S+ S DG+ +++ R S S+ +D+ ++
Sbjct: 826 SSNSS------DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879
Query: 652 YGCAD-GERTQATERVNSQPVNEKDSNDKN 680
+D E + +++ +S ++ DS+D +
Sbjct: 880 SDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909
Score = 37.4 bits (85), Expect = 0.091
Identities = 63/339 (18%), Positives = 122/339 (35%), Gaps = 26/339 (7%)
Query: 356 DKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSD 415
D ++ S+ + S+ S S++ ++ + S D+++ S S
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 416 IVSLDSQQDSMKYKDKWATDQEDCSD----------QDLAGTPDLGPQKS--PLWEKNGS 463
S DS S +++ D SD D + + D S N S
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830
Query: 464 ENSHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASN 523
++S + S+D D + ++ + D + DS + SS +S + +SN
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890
Query: 524 HCPQDAMIPHGDTDAIPVTFIGEVSD--DPVDSGLFSNRNNNAGSFDSEGVASRRDSLAP 581
D+D+ + + SD + DS SN ++N+ S DS + DS
Sbjct: 891 SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDS--- 947
Query: 582 LQAEHSQPHEKAREEVPALHPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTD 641
++ S + + + S D S+ S N +++ S S+ +D
Sbjct: 948 --SDSSNSSDSSNSSDSSNSSDSSDSNS------SDSSDSSNSSDSSDSSDSSDSSDSSD 999
Query: 642 NLNAKVKDKVYGCADGERTQATERVNSQPVNEKDSNDKN 680
+ N+ +D + + +S N DS+D +
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSN-SSDSSNSSDSSDSS 1037
Score = 37.4 bits (85), Expect = 0.091
Identities = 48/211 (22%), Positives = 77/211 (36%), Gaps = 7/211 (3%)
Query: 372 SGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQDSMKYKDK 431
S S S D + S S S + + DS S SD S DS S
Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSNSSDSSDSS 1148
Query: 432 WATDQEDCSDQ-DLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEFR 490
++D D SD D + + D N S++S + S+D D + +
Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1208
Query: 491 KTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTFIGEVSDD 550
+ ++ + + + S +D+S S + + D+ +D+ + S+D
Sbjct: 1209 DS-SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267
Query: 551 PVDSGLFSNRNNNAGS---FDSEGVASRRDS 578
DS S NN GS DSEG S +
Sbjct: 1268 ESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298
Score = 36.2 bits (82), Expect = 0.20
Identities = 59/313 (18%), Positives = 113/313 (36%), Gaps = 21/313 (6%)
Query: 371 GSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQDSMKYKD 430
GS S + D S+ + S G+ D + S SD DS S
Sbjct: 504 GSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSN---- 559
Query: 431 KWATDQEDCSDQDLA---GTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLLIAG 487
++D D SD D + + D S + + S++S + S+D D +
Sbjct: 560 --SSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617
Query: 488 EFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTFIGEV 547
+ + ++ + + DS SS ++S + N D+ +D+
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS-------SD 670
Query: 548 SDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPASHDV 607
S D DS S+ +N++ S DS ++ +S + S + + + + S D
Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS----DSSNSNSSDS 726
Query: 608 GKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERTQATERVN 667
S+ S + +++ S S+ +D+ N+ +D + + N
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786
Query: 668 SQPVNEKDSNDKN 680
N DS+D +
Sbjct: 787 DSS-NSSDSSDSS 798
Score = 35.0 bits (79), Expect = 0.45
Identities = 59/309 (19%), Positives = 107/309 (34%), Gaps = 21/309 (6%)
Query: 372 SGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQDSMKYKDK 431
S S S D S S S ++ + DS S S DS S
Sbjct: 777 SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836
Query: 432 WATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEFRK 491
++D D SD D + + S++S + S+D + + +
Sbjct: 837 NSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD 896
Query: 492 TLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTFIGEVSDDP 551
+ D D + +S ++ SS +S +SN +D+ S D
Sbjct: 897 SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNS-----NSSDS-------SNSSDS 944
Query: 552 VDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPASHDVGKGI 611
DS SN ++++ S DS + DS + ++ S + + + S D
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD----- 999
Query: 612 RVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERTQATERVNSQPV 671
SN S + +++ S S+ +D+ N+ +D + + +S
Sbjct: 1000 ---SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD-SSDSS 1055
Query: 672 NEKDSNDKN 680
N DS+D +
Sbjct: 1056 NSSDSSDSS 1064
>gi|217035133 hypothetical protein LOC55765 isoform 2 [Homo sapiens]
Length = 578
Score = 43.9 bits (102), Expect = 0.001
Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 20/132 (15%)
Query: 298 KKRRAPPPPGSGPPV--QDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPS-PLIPNRT 354
++R + PPP + P+ + AS+ SL + L++++ + P PPP P PPS PL P
Sbjct: 157 RRRNSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTL 216
Query: 355 EDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCF-----ASEDTTEDSGV 409
E + P G + SP+ AP S +ET S+ + +SE +E S
Sbjct: 217 EGLQ----------PTGPEAG-SPERAPVQNSPWKET-SLDHPYEKPRKSSEPWSESSSP 264
Query: 410 MSSPSDIVSLDS 421
++P D S S
Sbjct: 265 ATTPQDGPSASS 276
>gi|217035131 hypothetical protein LOC55765 isoform 1 [Homo sapiens]
Length = 663
Score = 43.9 bits (102), Expect = 0.001
Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 20/132 (15%)
Query: 298 KKRRAPPPPGSGPPV--QDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPS-PLIPNRT 354
++R + PPP + P+ + AS+ SL + L++++ + P PPP P PPS PL P
Sbjct: 242 RRRNSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTL 301
Query: 355 EDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCF-----ASEDTTEDSGV 409
E + P G + SP+ AP S +ET S+ + +SE +E S
Sbjct: 302 EGLQ----------PTGPEAG-SPERAPVQNSPWKET-SLDHPYEKPRKSSEPWSESSSP 349
Query: 410 MSSPSDIVSLDS 421
++P D S S
Sbjct: 350 ATTPQDGPSASS 361
>gi|50428935 BPY2 interacting protein 1 [Homo sapiens]
Length = 1059
Score = 43.5 bits (101), Expect = 0.001
Identities = 100/438 (22%), Positives = 157/438 (35%), Gaps = 69/438 (15%)
Query: 804 ESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGHVRVPAAH---------TTEV 854
++ QA PKP + S H G P+ G PP++ G P+A T
Sbjct: 553 KTNAQAAPKP--RKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPS 610
Query: 855 TFLKP-----QRRTSSQYVASAIAK-RIGAPKVHADVVRPHGYAEK--------GYAG-- 898
L P ++ AS+I + R +P+ H P +E+ G AG
Sbjct: 611 LELGPIPAGEEKALELPLAASSIPRPRTPSPESHRS---PAEGSERLSLSPLRGGEAGPD 667
Query: 899 KAPVLAAPPVTVKD--DRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIG 956
+P + P VT SPHS + V PP+ + + P R G
Sbjct: 668 ASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLR----G 723
Query: 957 PHRKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAP 1016
P + S + S + R V + + G SS ++S+ S+ R
Sbjct: 724 PRARRSASPHDVDL---CLVSPCEFEHRKAVPMAPAPASPG----SSNDSSARSQERAGG 776
Query: 1017 DGTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTD 1076
G + PP + + + APG + G G H L K D
Sbjct: 777 LGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPD 836
Query: 1077 GNETDSIWPPSIFGPK--------KKFKPVVQRP-----VPKDTSLHSALMEAIHSAGGK 1123
+ + P + PK + + + RP PK T + +A + + AGG
Sbjct: 837 PSSICMV-DPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGL--AGG- 892
Query: 1124 DR----LRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQS 1179
DR L +E + +G A LS + S A RG SG+ S R S+ +
Sbjct: 893 DRASRPLSARSEPSEKGGRAPLS-----RKSSTPKTATRGPSGSASSRPGVSATPPKSPV 947
Query: 1180 FRDAALSAQGSESPLLED 1197
+ D A GS + L+++
Sbjct: 948 YLDLAYLPSGSSAHLVDE 965
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 43.1 bits (100), Expect = 0.002
Identities = 49/219 (22%), Positives = 84/219 (38%), Gaps = 24/219 (10%)
Query: 147 PPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEE 206
PPK + ++ + Y + + + + + + A+ E+ H+ R A
Sbjct: 480 PPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFELRAFHI---RGEHAMIT 536
Query: 207 LELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSKGCLTT 266
L +++ L + + W E + + D+ K F V +++ + L
Sbjct: 537 ARLEETIENLKHELEHRWRGGCEERKDVCISTDDDCPPKT----FRNVCVQTDRETFLKP 592
Query: 267 PNSPSMHSRSLTLGPS-LSLGSISGVSVKSEMK----------------KRRAPPPPGSG 309
S S +RS L P L++ S+S +S ++ K ++ PPPP S
Sbjct: 593 CESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASI 652
Query: 310 PPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSP 348
PP S SL + P PPPP PPPP P
Sbjct: 653 PPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLP 691
Score = 32.3 bits (72), Expect = 2.9
Identities = 18/50 (36%), Positives = 20/50 (40%), Gaps = 15/50 (30%)
Query: 303 PPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPN 352
PPPP PP+ +S P PPPP P P SP PN
Sbjct: 681 PPPPPPPPPLPPPSSAG---------------PPPPPPPPPLPNSPAPPN 715
>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
interacting protein [Homo sapiens]
Length = 1211
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/122 (30%), Positives = 50/122 (40%), Gaps = 24/122 (19%)
Query: 240 ETDKEKKKF---LGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSE 296
E D E+ F G F N+RS++ C+++ G SL+ SIS
Sbjct: 704 ENDYEEMSFHDDQGSFVTNERSSASDCISSSEE----------GSSLTYSSISDHIPPPP 753
Query: 297 MKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQ-------KKKRRAPAPPPPQPPPPSPL 349
+ +PPPP P K S + S GS+ Q + P PPPP PPP P
Sbjct: 754 L----SPPPPPPLPFHDAKPSSRSSDGSRGPAQALAKPLTQLSHPVPPPPPPPLPPPVPC 809
Query: 350 IP 351
P
Sbjct: 810 AP 811
Score = 31.2 bits (69), Expect = 6.5
Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 1181 RDAALSAQGSESP---LLEDLGLLSPPAIPPPPPP-PSQALSAPRTASR 1225
+ ++ S+ GS P L + L LS P PPPPPP P AP SR
Sbjct: 768 KPSSRSSDGSRGPAQALAKPLTQLSHPVPPPPPPPLPPPVPCAPPMLSR 816
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 42.7 bits (99), Expect = 0.002
Identities = 46/202 (22%), Positives = 73/202 (36%), Gaps = 39/202 (19%)
Query: 270 PSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPG-------SGPPVQDKASEKVSL 322
P SR+ T P S V+V R PPPP SGPP + V
Sbjct: 311 PPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVG- 369
Query: 323 GSQIDLQKKKRRAPAPPPPQPPPPSPLIP----------------NRTEDKEENRKSTMV 366
AP PPPP PPPP P P N+ ++ R+ +
Sbjct: 370 ----------PVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQL 419
Query: 367 SLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTT-----EDSGVMSSPSDIVSLDS 421
+ S G +L + + + + S +++T SG++ + +++ S
Sbjct: 420 KKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRS 479
Query: 422 QQDSMKYKDKWATDQEDCSDQD 443
+ +D+ D+ED D D
Sbjct: 480 KAIHSSDEDEDEDDEEDFEDDD 501
Score = 38.1 bits (87), Expect = 0.053
Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 1193 PLLEDLGLLSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAA 1252
P + +G ++PP PPPPPPP P + TA + AL+D IR G A
Sbjct: 363 PSVLGVGPVAPP--PPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREG---A 417
Query: 1253 RLRKV 1257
+L+KV
Sbjct: 418 QLKKV 422
Score = 36.2 bits (82), Expect = 0.20
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 10/68 (14%)
Query: 292 SVKSEMKKRRAPPPPGS--GPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQ-----PP 344
+VK+E++++ PPPP S GPP + R AP PPP + PP
Sbjct: 267 AVKNELRRQAPPPPPPSRGGPPPPPPPPHN---SGPPPPPARGRGAPPPPPSRAPTAAPP 323
Query: 345 PPSPLIPN 352
PP P P+
Sbjct: 324 PPPPSRPS 331
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 42.4 bits (98), Expect = 0.003
Identities = 106/484 (21%), Positives = 172/484 (35%), Gaps = 74/484 (15%)
Query: 777 EKHLG-----RPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGE 831
EK LG +P+ S A+GPP P Q K P S E + +
Sbjct: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQ---------VKAEKPMDNSESSEESSDSAD 542
Query: 832 GRNQPPTMGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGY 891
P M + PA PQ + + + + ++ +V R G
Sbjct: 543 SEEAPAAMTAAQAK-PALKI-------PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGT 594
Query: 892 AEKGYAGKAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGA--- 948
A AG +P +A +D +SS S+++ K G V + G+ L V A
Sbjct: 595 ATSP-AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA-VTVGQAKSVGKGLQVKAASV 652
Query: 949 PPRGEV------IGPHRKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTS 1002
P +G + + P + T + A + S + S + + + K S
Sbjct: 653 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPA---QVKTSVK 709
Query: 1003 SQEASSASEPRRAPD--GTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTES 1060
+A + RAP GT P A +++ V+ P + G S
Sbjct: 710 KTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPAS 769
Query: 1061 HILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQ-RPVPKDTSLHSALMEAIHS 1119
+ + + + G E DS +++ + + Q +P K + +AL
Sbjct: 770 VPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL------ 823
Query: 1120 AGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQS 1179
A K+ RK A T G+ SA A + SG S+SEE S
Sbjct: 824 APAKESPRKGAAPTPPGKTGP----------SAAQAGKQDDSG---------SSSEESDS 864
Query: 1180 FRD---AALSAQGSESPLLEDLGLLSP---PAIPPPPPPPSQALSAPRTASRFSTGTLSN 1233
+ A SAQ + PL+ + P PA P P +QA S PR A + S+
Sbjct: 865 DGEAPAAVTSAQVIKPPLI----FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 920
Query: 1234 TADA 1237
++++
Sbjct: 921 SSES 924
Score = 39.3 bits (90), Expect = 0.024
Identities = 120/622 (19%), Positives = 215/622 (34%), Gaps = 71/622 (11%)
Query: 280 GPSLSLGSISGVSVKSEMKKRRAPPPPG-SGPPVQDKASEKVSLGSQIDLQKKKRRAPAP 338
G + +G+ S + K +K AP PPG +GP V + K SQ ++ AP
Sbjct: 289 GKTSQVGAASAPA-KESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 347
Query: 339 PPPQPPPPSPLIPNRTED-KEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSC 397
+P +P + + KE RK + P +G A QV +E S S
Sbjct: 348 AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTG-----PAAAQVQVGKQEEDSRSSS 402
Query: 398 FASEDTTEDSGVMSS-------------PSDIVSLD--------------SQQDSMKYKD 430
S+ E M++ P+ + +
Sbjct: 403 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 462
Query: 431 KWATDQEDCSDQDLAGTPDLGPQK-SPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEF 489
KW D E S++ + P +P EK+ + + ++ +A +
Sbjct: 463 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 522
Query: 490 R-KTLAELDEDLEEMEDSYETD--TSSLTSSIHGASNHCPQDAMIPH--GDTDAIPVTFI 544
+ + + E EE DS +++ +++T++ + PQ P T + V +
Sbjct: 523 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 582
Query: 545 GEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPAS 604
+ P +G + AGS + ++R + +E S E+ + A
Sbjct: 583 RVGTQAPRKAG---TATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 639
Query: 605 HDVGKGIRVALSNISKDGNLME---------TAPRVTSFASNLHTDNLNAKVKDKVYGCA 655
VGKG++V +++ G+L + T P VT + D+ +++ + +
Sbjct: 640 -SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE------S 692
Query: 656 DGERTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKS 715
D E A+ V + + AA S PGK K
Sbjct: 693 DSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 752
Query: 716 EMRCYDRDVSLSTGAIKIDELGNLVSPHA---TGIRIISLSS---SVPEAESQPIGKVRE 769
+R L+ G + +G V+ A TG S SS S E E++ + +V+
Sbjct: 753 PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKP 812
Query: 770 FWRCNSVEKHLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPL 829
+ + + L ES +G + P P P + + + +G P
Sbjct: 813 SGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPA 870
Query: 830 GEGRNQ---PPTMGMGHVRVPA 848
Q PP + + R PA
Sbjct: 871 AVTSAQVIKPPLIFVDPNRSPA 892
Score = 30.8 bits (68), Expect = 8.5
Identities = 31/127 (24%), Positives = 42/127 (33%), Gaps = 26/127 (20%)
Query: 294 KSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLI--- 350
K +K AP PPG P +A ++ GS + APA PLI
Sbjct: 827 KESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 886
Query: 351 PNRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVM 410
PNR SP G ++A+ + ASE T S
Sbjct: 887 PNR-----------------------SPAGPAATPAQAQAASTPRKARASESTARSSSSE 923
Query: 411 SSPSDIV 417
S D++
Sbjct: 924 SEDEDVI 930
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 42.4 bits (98), Expect = 0.003
Identities = 106/484 (21%), Positives = 172/484 (35%), Gaps = 74/484 (15%)
Query: 777 EKHLG-----RPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGE 831
EK LG +P+ S A+GPP P Q K P S E + +
Sbjct: 569 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQ---------VKAEKPMDNSESSEESSDSAD 619
Query: 832 GRNQPPTMGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGY 891
P M + PA PQ + + + + ++ +V R G
Sbjct: 620 SEEAPAAMTAAQAK-PALKI-------PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGT 671
Query: 892 AEKGYAGKAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGA--- 948
A AG +P +A +D +SS S+++ K G V + G+ L V A
Sbjct: 672 ATSP-AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA-VTVGQAKSVGKGLQVKAASV 729
Query: 949 PPRGEV------IGPHRKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTS 1002
P +G + + P + T + A + S + S + + + K S
Sbjct: 730 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPA---QVKTSVK 786
Query: 1003 SQEASSASEPRRAPD--GTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTES 1060
+A + RAP GT P A +++ V+ P + G S
Sbjct: 787 KTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPAS 846
Query: 1061 HILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQ-RPVPKDTSLHSALMEAIHS 1119
+ + + + G E DS +++ + + Q +P K + +AL
Sbjct: 847 VPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL------ 900
Query: 1120 AGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQS 1179
A K+ RK A T G+ SA A + SG S+SEE S
Sbjct: 901 APAKESPRKGAAPTPPGKTGP----------SAAQAGKQDDSG---------SSSEESDS 941
Query: 1180 FRD---AALSAQGSESPLLEDLGLLSP---PAIPPPPPPPSQALSAPRTASRFSTGTLSN 1233
+ A SAQ + PL+ + P PA P P +QA S PR A + S+
Sbjct: 942 DGEAPAAVTSAQVIKPPLI----FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 997
Query: 1234 TADA 1237
++++
Sbjct: 998 SSES 1001
Score = 39.3 bits (90), Expect = 0.024
Identities = 120/622 (19%), Positives = 215/622 (34%), Gaps = 71/622 (11%)
Query: 280 GPSLSLGSISGVSVKSEMKKRRAPPPPG-SGPPVQDKASEKVSLGSQIDLQKKKRRAPAP 338
G + +G+ S + K +K AP PPG +GP V + K SQ ++ AP
Sbjct: 366 GKTSQVGAASAPA-KESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424
Query: 339 PPPQPPPPSPLIPNRTED-KEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSC 397
+P +P + + KE RK + P +G A QV +E S S
Sbjct: 425 AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTG-----PAAAQVQVGKQEEDSRSSS 479
Query: 398 FASEDTTEDSGVMSS-------------PSDIVSLD--------------SQQDSMKYKD 430
S+ E M++ P+ + +
Sbjct: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539
Query: 431 KWATDQEDCSDQDLAGTPDLGPQK-SPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEF 489
KW D E S++ + P +P EK+ + + ++ +A +
Sbjct: 540 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599
Query: 490 R-KTLAELDEDLEEMEDSYETD--TSSLTSSIHGASNHCPQDAMIPH--GDTDAIPVTFI 544
+ + + E EE DS +++ +++T++ + PQ P T + V +
Sbjct: 600 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 659
Query: 545 GEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPAS 604
+ P +G + AGS + ++R + +E S E+ + A
Sbjct: 660 RVGTQAPRKAG---TATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 716
Query: 605 HDVGKGIRVALSNISKDGNLME---------TAPRVTSFASNLHTDNLNAKVKDKVYGCA 655
VGKG++V +++ G+L + T P VT + D+ +++ + +
Sbjct: 717 -SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE------S 769
Query: 656 DGERTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKS 715
D E A+ V + + AA S PGK K
Sbjct: 770 DSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 829
Query: 716 EMRCYDRDVSLSTGAIKIDELGNLVSPHA---TGIRIISLSS---SVPEAESQPIGKVRE 769
+R L+ G + +G V+ A TG S SS S E E++ + +V+
Sbjct: 830 PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKP 889
Query: 770 FWRCNSVEKHLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPL 829
+ + + L ES +G + P P P + + + +G P
Sbjct: 890 SGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPA 947
Query: 830 GEGRNQ---PPTMGMGHVRVPA 848
Q PP + + R PA
Sbjct: 948 AVTSAQVIKPPLIFVDPNRSPA 969
Score = 30.8 bits (68), Expect = 8.5
Identities = 31/127 (24%), Positives = 42/127 (33%), Gaps = 26/127 (20%)
Query: 294 KSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLI--- 350
K +K AP PPG P +A ++ GS + APA PLI
Sbjct: 904 KESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 963
Query: 351 PNRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVM 410
PNR SP G ++A+ + ASE T S
Sbjct: 964 PNR-----------------------SPAGPAATPAQAQAASTPRKARASESTARSSSSE 1000
Query: 411 SSPSDIV 417
S D++
Sbjct: 1001 SEDEDVI 1007
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 42.4 bits (98), Expect = 0.003
Identities = 106/484 (21%), Positives = 172/484 (35%), Gaps = 74/484 (15%)
Query: 777 EKHLG-----RPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGE 831
EK LG +P+ S A+GPP P Q K P S E + +
Sbjct: 569 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQ---------VKAEKPMDNSESSEESSDSAD 619
Query: 832 GRNQPPTMGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGY 891
P M + PA PQ + + + + ++ +V R G
Sbjct: 620 SEEAPAAMTAAQAK-PALKI-------PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGT 671
Query: 892 AEKGYAGKAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGA--- 948
A AG +P +A +D +SS S+++ K G V + G+ L V A
Sbjct: 672 ATSP-AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA-VTVGQAKSVGKGLQVKAASV 729
Query: 949 PPRGEV------IGPHRKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTS 1002
P +G + + P + T + A + S + S + + + K S
Sbjct: 730 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPA---QVKTSVK 786
Query: 1003 SQEASSASEPRRAPD--GTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTES 1060
+A + RAP GT P A +++ V+ P + G S
Sbjct: 787 KTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPAS 846
Query: 1061 HILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQ-RPVPKDTSLHSALMEAIHS 1119
+ + + + G E DS +++ + + Q +P K + +AL
Sbjct: 847 VPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL------ 900
Query: 1120 AGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQS 1179
A K+ RK A T G+ SA A + SG S+SEE S
Sbjct: 901 APAKESPRKGAAPTPPGKTGP----------SAAQAGKQDDSG---------SSSEESDS 941
Query: 1180 FRD---AALSAQGSESPLLEDLGLLSP---PAIPPPPPPPSQALSAPRTASRFSTGTLSN 1233
+ A SAQ + PL+ + P PA P P +QA S PR A + S+
Sbjct: 942 DGEAPAAVTSAQVIKPPLI----FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 997
Query: 1234 TADA 1237
++++
Sbjct: 998 SSES 1001
Score = 39.3 bits (90), Expect = 0.024
Identities = 120/622 (19%), Positives = 215/622 (34%), Gaps = 71/622 (11%)
Query: 280 GPSLSLGSISGVSVKSEMKKRRAPPPPG-SGPPVQDKASEKVSLGSQIDLQKKKRRAPAP 338
G + +G+ S + K +K AP PPG +GP V + K SQ ++ AP
Sbjct: 366 GKTSQVGAASAPA-KESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424
Query: 339 PPPQPPPPSPLIPNRTED-KEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSC 397
+P +P + + KE RK + P +G A QV +E S S
Sbjct: 425 AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTG-----PAAAQVQVGKQEEDSRSSS 479
Query: 398 FASEDTTEDSGVMSS-------------PSDIVSLD--------------SQQDSMKYKD 430
S+ E M++ P+ + +
Sbjct: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539
Query: 431 KWATDQEDCSDQDLAGTPDLGPQK-SPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEF 489
KW D E S++ + P +P EK+ + + ++ +A +
Sbjct: 540 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599
Query: 490 R-KTLAELDEDLEEMEDSYETD--TSSLTSSIHGASNHCPQDAMIPH--GDTDAIPVTFI 544
+ + + E EE DS +++ +++T++ + PQ P T + V +
Sbjct: 600 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 659
Query: 545 GEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPAS 604
+ P +G + AGS + ++R + +E S E+ + A
Sbjct: 660 RVGTQAPRKAG---TATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 716
Query: 605 HDVGKGIRVALSNISKDGNLME---------TAPRVTSFASNLHTDNLNAKVKDKVYGCA 655
VGKG++V +++ G+L + T P VT + D+ +++ + +
Sbjct: 717 -SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE------S 769
Query: 656 DGERTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKS 715
D E A+ V + + AA S PGK K
Sbjct: 770 DSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 829
Query: 716 EMRCYDRDVSLSTGAIKIDELGNLVSPHA---TGIRIISLSS---SVPEAESQPIGKVRE 769
+R L+ G + +G V+ A TG S SS S E E++ + +V+
Sbjct: 830 PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKP 889
Query: 770 FWRCNSVEKHLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPL 829
+ + + L ES +G + P P P + + + +G P
Sbjct: 890 SGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPA 947
Query: 830 GEGRNQ---PPTMGMGHVRVPA 848
Q PP + + R PA
Sbjct: 948 AVTSAQVIKPPLIFVDPNRSPA 969
Score = 30.8 bits (68), Expect = 8.5
Identities = 31/127 (24%), Positives = 42/127 (33%), Gaps = 26/127 (20%)
Query: 294 KSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLI--- 350
K +K AP PPG P +A ++ GS + APA PLI
Sbjct: 904 KESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 963
Query: 351 PNRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVM 410
PNR SP G ++A+ + ASE T S
Sbjct: 964 PNR-----------------------SPAGPAATPAQAQAASTPRKARASESTARSSSSE 1000
Query: 411 SSPSDIV 417
S D++
Sbjct: 1001 SEDEDVI 1007
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 42.4 bits (98), Expect = 0.003
Identities = 106/484 (21%), Positives = 172/484 (35%), Gaps = 74/484 (15%)
Query: 777 EKHLG-----RPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGE 831
EK LG +P+ S A+GPP P Q K P S E + +
Sbjct: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQ---------VKAEKPMDNSESSEESSDSAD 542
Query: 832 GRNQPPTMGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGY 891
P M + PA PQ + + + + ++ +V R G
Sbjct: 543 SEEAPAAMTAAQAK-PALKI-------PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGT 594
Query: 892 AEKGYAGKAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGA--- 948
A AG +P +A +D +SS S+++ K G V + G+ L V A
Sbjct: 595 ATSP-AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA-VTVGQAKSVGKGLQVKAASV 652
Query: 949 PPRGEV------IGPHRKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTS 1002
P +G + + P + T + A + S + S + + + K S
Sbjct: 653 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPA---QVKTSVK 709
Query: 1003 SQEASSASEPRRAPD--GTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTES 1060
+A + RAP GT P A +++ V+ P + G S
Sbjct: 710 KTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPAS 769
Query: 1061 HILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQ-RPVPKDTSLHSALMEAIHS 1119
+ + + + G E DS +++ + + Q +P K + +AL
Sbjct: 770 VPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL------ 823
Query: 1120 AGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQS 1179
A K+ RK A T G+ SA A + SG S+SEE S
Sbjct: 824 APAKESPRKGAAPTPPGKTGP----------SAAQAGKQDDSG---------SSSEESDS 864
Query: 1180 FRD---AALSAQGSESPLLEDLGLLSP---PAIPPPPPPPSQALSAPRTASRFSTGTLSN 1233
+ A SAQ + PL+ + P PA P P +QA S PR A + S+
Sbjct: 865 DGEAPAAVTSAQVIKPPLI----FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 920
Query: 1234 TADA 1237
++++
Sbjct: 921 SSES 924
Score = 39.3 bits (90), Expect = 0.024
Identities = 120/622 (19%), Positives = 215/622 (34%), Gaps = 71/622 (11%)
Query: 280 GPSLSLGSISGVSVKSEMKKRRAPPPPG-SGPPVQDKASEKVSLGSQIDLQKKKRRAPAP 338
G + +G+ S + K +K AP PPG +GP V + K SQ ++ AP
Sbjct: 289 GKTSQVGAASAPA-KESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 347
Query: 339 PPPQPPPPSPLIPNRTED-KEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSC 397
+P +P + + KE RK + P +G A QV +E S S
Sbjct: 348 AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTG-----PAAAQVQVGKQEEDSRSSS 402
Query: 398 FASEDTTEDSGVMSS-------------PSDIVSLD--------------SQQDSMKYKD 430
S+ E M++ P+ + +
Sbjct: 403 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 462
Query: 431 KWATDQEDCSDQDLAGTPDLGPQK-SPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEF 489
KW D E S++ + P +P EK+ + + ++ +A +
Sbjct: 463 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 522
Query: 490 R-KTLAELDEDLEEMEDSYETD--TSSLTSSIHGASNHCPQDAMIPH--GDTDAIPVTFI 544
+ + + E EE DS +++ +++T++ + PQ P T + V +
Sbjct: 523 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 582
Query: 545 GEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPAS 604
+ P +G + AGS + ++R + +E S E+ + A
Sbjct: 583 RVGTQAPRKAG---TATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 639
Query: 605 HDVGKGIRVALSNISKDGNLME---------TAPRVTSFASNLHTDNLNAKVKDKVYGCA 655
VGKG++V +++ G+L + T P VT + D+ +++ + +
Sbjct: 640 -SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE------S 692
Query: 656 DGERTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKS 715
D E A+ V + + AA S PGK K
Sbjct: 693 DSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 752
Query: 716 EMRCYDRDVSLSTGAIKIDELGNLVSPHA---TGIRIISLSS---SVPEAESQPIGKVRE 769
+R L+ G + +G V+ A TG S SS S E E++ + +V+
Sbjct: 753 PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKP 812
Query: 770 FWRCNSVEKHLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPL 829
+ + + L ES +G + P P P + + + +G P
Sbjct: 813 SGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPA 870
Query: 830 GEGRNQ---PPTMGMGHVRVPA 848
Q PP + + R PA
Sbjct: 871 AVTSAQVIKPPLIFVDPNRSPA 892
Score = 30.8 bits (68), Expect = 8.5
Identities = 31/127 (24%), Positives = 42/127 (33%), Gaps = 26/127 (20%)
Query: 294 KSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLI--- 350
K +K AP PPG P +A ++ GS + APA PLI
Sbjct: 827 KESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 886
Query: 351 PNRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVM 410
PNR SP G ++A+ + ASE T S
Sbjct: 887 PNR-----------------------SPAGPAATPAQAQAASTPRKARASESTARSSSSE 923
Query: 411 SSPSDIV 417
S D++
Sbjct: 924 SEDEDVI 930
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 42.4 bits (98), Expect = 0.003
Identities = 106/484 (21%), Positives = 172/484 (35%), Gaps = 74/484 (15%)
Query: 777 EKHLG-----RPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGE 831
EK LG +P+ S A+GPP P Q K P S E + +
Sbjct: 569 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQ---------VKAEKPMDNSESSEESSDSAD 619
Query: 832 GRNQPPTMGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGY 891
P M + PA PQ + + + + ++ +V R G
Sbjct: 620 SEEAPAAMTAAQAK-PALKI-------PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGT 671
Query: 892 AEKGYAGKAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGA--- 948
A AG +P +A +D +SS S+++ K G V + G+ L V A
Sbjct: 672 ATSP-AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA-VTVGQAKSVGKGLQVKAASV 729
Query: 949 PPRGEV------IGPHRKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTS 1002
P +G + + P + T + A + S + S + + + K S
Sbjct: 730 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPA---QVKTSVK 786
Query: 1003 SQEASSASEPRRAPD--GTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTES 1060
+A + RAP GT P A +++ V+ P + G S
Sbjct: 787 KTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPAS 846
Query: 1061 HILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQ-RPVPKDTSLHSALMEAIHS 1119
+ + + + G E DS +++ + + Q +P K + +AL
Sbjct: 847 VPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL------ 900
Query: 1120 AGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQS 1179
A K+ RK A T G+ SA A + SG S+SEE S
Sbjct: 901 APAKESPRKGAAPTPPGKTGP----------SAAQAGKQDDSG---------SSSEESDS 941
Query: 1180 FRD---AALSAQGSESPLLEDLGLLSP---PAIPPPPPPPSQALSAPRTASRFSTGTLSN 1233
+ A SAQ + PL+ + P PA P P +QA S PR A + S+
Sbjct: 942 DGEAPAAVTSAQVIKPPLI----FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 997
Query: 1234 TADA 1237
++++
Sbjct: 998 SSES 1001
Score = 39.3 bits (90), Expect = 0.024
Identities = 120/622 (19%), Positives = 215/622 (34%), Gaps = 71/622 (11%)
Query: 280 GPSLSLGSISGVSVKSEMKKRRAPPPPG-SGPPVQDKASEKVSLGSQIDLQKKKRRAPAP 338
G + +G+ S + K +K AP PPG +GP V + K SQ ++ AP
Sbjct: 366 GKTSQVGAASAPA-KESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424
Query: 339 PPPQPPPPSPLIPNRTED-KEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSC 397
+P +P + + KE RK + P +G A QV +E S S
Sbjct: 425 AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTG-----PAAAQVQVGKQEEDSRSSS 479
Query: 398 FASEDTTEDSGVMSS-------------PSDIVSLD--------------SQQDSMKYKD 430
S+ E M++ P+ + +
Sbjct: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539
Query: 431 KWATDQEDCSDQDLAGTPDLGPQK-SPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEF 489
KW D E S++ + P +P EK+ + + ++ +A +
Sbjct: 540 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599
Query: 490 R-KTLAELDEDLEEMEDSYETD--TSSLTSSIHGASNHCPQDAMIPH--GDTDAIPVTFI 544
+ + + E EE DS +++ +++T++ + PQ P T + V +
Sbjct: 600 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 659
Query: 545 GEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPAS 604
+ P +G + AGS + ++R + +E S E+ + A
Sbjct: 660 RVGTQAPRKAG---TATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 716
Query: 605 HDVGKGIRVALSNISKDGNLME---------TAPRVTSFASNLHTDNLNAKVKDKVYGCA 655
VGKG++V +++ G+L + T P VT + D+ +++ + +
Sbjct: 717 -SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE------S 769
Query: 656 DGERTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKS 715
D E A+ V + + AA S PGK K
Sbjct: 770 DSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 829
Query: 716 EMRCYDRDVSLSTGAIKIDELGNLVSPHA---TGIRIISLSS---SVPEAESQPIGKVRE 769
+R L+ G + +G V+ A TG S SS S E E++ + +V+
Sbjct: 830 PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKP 889
Query: 770 FWRCNSVEKHLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPL 829
+ + + L ES +G + P P P + + + +G P
Sbjct: 890 SGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPA 947
Query: 830 GEGRNQ---PPTMGMGHVRVPA 848
Q PP + + R PA
Sbjct: 948 AVTSAQVIKPPLIFVDPNRSPA 969
Score = 30.8 bits (68), Expect = 8.5
Identities = 31/127 (24%), Positives = 42/127 (33%), Gaps = 26/127 (20%)
Query: 294 KSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLI--- 350
K +K AP PPG P +A ++ GS + APA PLI
Sbjct: 904 KESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 963
Query: 351 PNRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVM 410
PNR SP G ++A+ + ASE T S
Sbjct: 964 PNR-----------------------SPAGPAATPAQAQAASTPRKARASESTARSSSSE 1000
Query: 411 SSPSDIV 417
S D++
Sbjct: 1001 SEDEDVI 1007
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 42.0 bits (97), Expect = 0.004
Identities = 41/154 (26%), Positives = 63/154 (40%), Gaps = 11/154 (7%)
Query: 232 RKSSLGNDETDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGV 291
R+S+L + EK+ G K+ K+ + + P + S +L++G + G+ G
Sbjct: 464 RQSTLEKKIHELEKQ---GTIKIQKKGDGDIAIL----PVVASGTLSMGSEVVAGNSVGP 516
Query: 292 SVKSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIP 351
++ + PPPP PP D E V G P PPPP PPPP P P
Sbjct: 517 TMGAASSGPLPPPPPPL-PPSSD-TPETVQNGPVTPPMPPP--PPPPPPPPPPPPPPPPP 572
Query: 352 NRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVL 385
E + ++ PL S +P V+
Sbjct: 573 PLPGPAAETVPAPPLAPPLPSAPPLPGTSSPTVV 606
Score = 31.2 bits (69), Expect = 6.5
Identities = 12/24 (50%), Positives = 16/24 (66%)
Query: 1190 SESPLLEDLGLLSPPAIPPPPPPP 1213
S++P G ++PP PPPPPPP
Sbjct: 537 SDTPETVQNGPVTPPMPPPPPPPP 560
>gi|112789555 ADAM metallopeptidase with thrombospondin type 1
motif, 19 preproprotein [Homo sapiens]
Length = 1207
Score = 42.0 bits (97), Expect = 0.004
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 9/94 (9%)
Query: 274 SRSLTLGPSLSLGSISGVS----VKSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQ 329
+R+ G S + S++ V V+ + R PPPP G ++ S+++ GS
Sbjct: 72 ARAQAAGSSREVRSVAPVPLEEPVEGRSESRLRPPPPSEGEEDEELESQELPRGSS-GAA 130
Query: 330 KKKRRAPA----PPPPQPPPPSPLIPNRTEDKEE 359
APA PPPPQPPP P + D +E
Sbjct: 131 ALSPGAPASWQPPPPPQPPPSPPPAQHAEPDGDE 164
>gi|46094081 development and differentiation enhancing factor 1 [Homo
sapiens]
Length = 1129
Score = 41.6 bits (96), Expect = 0.005
Identities = 63/271 (23%), Positives = 90/271 (33%), Gaps = 37/271 (13%)
Query: 237 GNDETDKEKKKFLGFFKVNKRSNSKGCL---TTPNSPSMHSRSLTLGPSLSLGSISGVSV 293
G + K KF G + + S++K L P P + T SL +I
Sbjct: 862 GPSSSSKTTNKFEGLSQQSSTSSAKTALGPRVLPKLPQKVALRKTDHLSLDKATIPPEIF 921
Query: 294 KSEMKKRRAP--PPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIP 351
+ + P PPPG PP + + K +G DL K P P PP P +
Sbjct: 922 QKSSQLAELPQKPPPGDLPPKPTELAPKPQIG---DLPPKPGELPPKPQLGDLPPKPQLS 978
Query: 352 NRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMS 411
+ K M LP PQ +G A T + S
Sbjct: 979 DLPP------KPQMKDLP----------PKPQ----------LGDLLAKSQTGDVSPKAQ 1012
Query: 412 SPSDIVSLDSQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTE 471
PS++ D Q+ S+ TP L PL K + + +R
Sbjct: 1013 QPSEVTLKSHPLDLSPNVQSRDAIQKQASEDSNDLTPTLPETPVPLPRKINTGKNKVRRV 1072
Query: 472 KAV---TASNDEEDLLIAGEFRKTLAELDED 499
K + A ND+E I GE E D++
Sbjct: 1073 KTIYDCQADNDDELTFIEGEVIIVTGEEDQE 1103
>gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Homo
sapiens]
Length = 728
Score = 41.6 bits (96), Expect = 0.005
Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 1159 GHSGTCSLRKVASSASEELQSFRDAALSAQG--SESPLLEDLGLLSPPAIPPPPPPPSQA 1216
GHSG+ + + A+ A+ LQ +A A+G E E +G P IP PPPPS A
Sbjct: 439 GHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSA 498
Query: 1217 LSAPRTA 1223
+ P +A
Sbjct: 499 TNIPSSA 505
Score = 38.1 bits (87), Expect = 0.053
Identities = 68/338 (20%), Positives = 124/338 (36%), Gaps = 30/338 (8%)
Query: 231 FRKSSLGNDETDKEKKK----------FLGFFKVNKRSNSKGCLTTPNSPS-MHSRSLTL 279
F++ +E +KEK++ F+ V+ + N +G P +P + +R L
Sbjct: 187 FQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQ 246
Query: 280 GPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQ-DKASEKVSLGSQIDLQKKKRRAPAP 338
G V ++ E + PP Q D+ ++ + D +++ ++ P P
Sbjct: 247 ERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPP 306
Query: 339 PPPQPPPPSPLIPNRT---EDKEENRKSTMVSLPLGSGSHCSP-DGAPQVLSEAEETVSV 394
P PPP P P++ +D + + P SP G S+ +E + +
Sbjct: 307 PETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRI 366
Query: 395 GSCFASEDTTEDSGVMSSPSD----IVSLDSQQDSMKYKDKWATD----QEDCSDQDLAG 446
G D + SD LD + S+K + TD +E + +
Sbjct: 367 GLLDPRWLEQRDRSIREKQSDDEVYAPGLDI-ESSLKQLAERRTDIFGVEETAIGKKIGE 425
Query: 447 TPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDLEEMEDS 506
P++ W+ G S RT++A A+ ++ + A K L D+ E++ S
Sbjct: 426 EEIQKPEEKVTWD--GHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPS 483
Query: 507 YETDTSSLTSSIHGASN---HCPQDAMIPHGDTDAIPV 541
+ A+N P +P T PV
Sbjct: 484 KPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPV 521
>gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo
sapiens]
Length = 793
Score = 41.6 bits (96), Expect = 0.005
Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 1159 GHSGTCSLRKVASSASEELQSFRDAALSAQG--SESPLLEDLGLLSPPAIPPPPPPPSQA 1216
GHSG+ + + A+ A+ LQ +A A+G E E +G P IP PPPPS A
Sbjct: 504 GHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSA 563
Query: 1217 LSAPRTA 1223
+ P +A
Sbjct: 564 TNIPSSA 570
Score = 38.1 bits (87), Expect = 0.053
Identities = 68/338 (20%), Positives = 124/338 (36%), Gaps = 30/338 (8%)
Query: 231 FRKSSLGNDETDKEKKK----------FLGFFKVNKRSNSKGCLTTPNSPS-MHSRSLTL 279
F++ +E +KEK++ F+ V+ + N +G P +P + +R L
Sbjct: 252 FQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQ 311
Query: 280 GPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQ-DKASEKVSLGSQIDLQKKKRRAPAP 338
G V ++ E + PP Q D+ ++ + D +++ ++ P P
Sbjct: 312 ERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPP 371
Query: 339 PPPQPPPPSPLIPNRT---EDKEENRKSTMVSLPLGSGSHCSP-DGAPQVLSEAEETVSV 394
P PPP P P++ +D + + P SP G S+ +E + +
Sbjct: 372 PETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRI 431
Query: 395 GSCFASEDTTEDSGVMSSPSD----IVSLDSQQDSMKYKDKWATD----QEDCSDQDLAG 446
G D + SD LD + S+K + TD +E + +
Sbjct: 432 GLLDPRWLEQRDRSIREKQSDDEVYAPGLDI-ESSLKQLAERRTDIFGVEETAIGKKIGE 490
Query: 447 TPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDLEEMEDS 506
P++ W+ G S RT++A A+ ++ + A K L D+ E++ S
Sbjct: 491 EEIQKPEEKVTWD--GHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPS 548
Query: 507 YETDTSSLTSSIHGASN---HCPQDAMIPHGDTDAIPV 541
+ A+N P +P T PV
Sbjct: 549 KPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPV 586
>gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]
Length = 429
Score = 41.2 bits (95), Expect = 0.006
Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 21/104 (20%)
Query: 277 LTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAP 336
L+ G +LS+ + +S+KSE P+ G Q Q+++++ P
Sbjct: 308 LSQGSNLSINTNQNISIKSE--------------PISPPRDRMTPSGFQQQQQQQQQQQP 353
Query: 337 APPP-PQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPD 379
PPP PQP PP P + ++E +S + SL S S+ D
Sbjct: 354 PPPPQPQPQPPQP------QPRQEMGRSPVDSLSSSSSSYDGSD 391
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,403,819
Number of Sequences: 37866
Number of extensions: 3565902
Number of successful extensions: 37420
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 582
Number of HSP's that attempted gapping in prelim test: 25040
Number of HSP's gapped (non-prelim): 10223
length of query: 1261
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1147
effective length of database: 13,930,794
effective search space: 15978620718
effective search space used: 15978620718
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.