Guide to the Human Genome
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Search of human proteins with 31377591

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31377591 sestrin 3 [Homo sapiens]
         (492 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31377591 sestrin 3 [Homo sapiens]                                 1003   0.0  
gi|7657437 sestrin 1 [Homo sapiens]                                   613   e-175
gi|13899299 sestrin 2 [Homo sapiens]                                  518   e-147
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is...    37   0.031
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is...    37   0.031
gi|45643129 guanine nucleotide binding protein-like 3 isoform 2 ...    36   0.091
gi|45643127 guanine nucleotide binding protein-like 3 isoform 2 ...    36   0.091
gi|45593130 guanine nucleotide binding protein-like 3 isoform 1 ...    36   0.091
gi|6631095 minichromosome maintenance complex component 3 [Homo ...    34   0.27 
gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]                    33   0.45 
gi|131889097 cancer susceptibility candidate 1 isoform b [Homo s...    33   0.45 
gi|131889447 cancer susceptibility candidate 1 isoform c [Homo s...    33   0.45 
gi|131888105 cancer susceptibility candidate 1 isoform a [Homo s...    33   0.45 
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]                   33   0.59 
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       33   0.59 
gi|149192855 HLA-B associated transcript 2-like [Homo sapiens]         33   0.59 
gi|147903302 MAP7 domain containing 3 [Homo sapiens]                   33   0.77 
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    32   1.0  
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    32   1.0  
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    32   1.0  
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    32   1.0  
gi|18490978 intermediate filament family orphan isoform 2 [Homo ...    32   1.0  
gi|89213250 intermediate filament family orphan isoform 4 [Homo ...    32   1.0  
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     32   1.3  
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     32   1.3  
gi|82830424 gon-4-like isoform a [Homo sapiens]                        32   1.3  
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    32   1.3  
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    32   1.3  
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    32   1.3  
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    32   1.3  

>gi|31377591 sestrin 3 [Homo sapiens]
          Length = 492

 Score = 1003 bits (2592), Expect = 0.0
 Identities = 492/492 (100%), Positives = 492/492 (100%)

Query: 1   MNRGGGSPSAAANYLLCTNCRKVLRKDKRIRVSQPLTRGPSAFIPEKEVVQANTVDERTN 60
           MNRGGGSPSAAANYLLCTNCRKVLRKDKRIRVSQPLTRGPSAFIPEKEVVQANTVDERTN
Sbjct: 1   MNRGGGSPSAAANYLLCTNCRKVLRKDKRIRVSQPLTRGPSAFIPEKEVVQANTVDERTN 60

Query: 61  FLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYMLRMDGPLPLPYRHYIAIMAAARHQ 120
           FLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYMLRMDGPLPLPYRHYIAIMAAARHQ
Sbjct: 61  FLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYMLRMDGPLPLPYRHYIAIMAAARHQ 120

Query: 121 CSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLKNLNEINKLLAHRPWLITKEHIQKLVKT 180
           CSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLKNLNEINKLLAHRPWLITKEHIQKLVKT
Sbjct: 121 CSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLKNLNEINKLLAHRPWLITKEHIQKLVKT 180

Query: 181 GENNWSLPELVHAVVLLAHYHALASFVFGSGINPERDPEISNGFRLISVNNFCVCDLAND 240
           GENNWSLPELVHAVVLLAHYHALASFVFGSGINPERDPEISNGFRLISVNNFCVCDLAND
Sbjct: 181 GENNWSLPELVHAVVLLAHYHALASFVFGSGINPERDPEISNGFRLISVNNFCVCDLAND 240

Query: 241 NNIENASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFV 300
           NNIENASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFV
Sbjct: 241 NNIENASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFV 300

Query: 301 VSGDTFHSFPHSDFEDDMIITSDVSRYIEDPGFGYEDFARRGEEHLPTFRAQDYTWENHG 360
           VSGDTFHSFPHSDFEDDMIITSDVSRYIEDPGFGYEDFARRGEEHLPTFRAQDYTWENHG
Sbjct: 301 VSGDTFHSFPHSDFEDDMIITSDVSRYIEDPGFGYEDFARRGEEHLPTFRAQDYTWENHG 360

Query: 361 FSLVNRLYSDIGHLLDEKFRMVYNLTYNTMATHEDVDTTMLRRALFNYVHCMFGIRYDDY 420
           FSLVNRLYSDIGHLLDEKFRMVYNLTYNTMATHEDVDTTMLRRALFNYVHCMFGIRYDDY
Sbjct: 361 FSLVNRLYSDIGHLLDEKFRMVYNLTYNTMATHEDVDTTMLRRALFNYVHCMFGIRYDDY 420

Query: 421 DYGEVNQLLERSLKVYIKTVTCYPERTTKRMYDSYWRQFKHSEKVHVNLLLMEARMQAEL 480
           DYGEVNQLLERSLKVYIKTVTCYPERTTKRMYDSYWRQFKHSEKVHVNLLLMEARMQAEL
Sbjct: 421 DYGEVNQLLERSLKVYIKTVTCYPERTTKRMYDSYWRQFKHSEKVHVNLLLMEARMQAEL 480

Query: 481 LYALRAITRHLT 492
           LYALRAITRHLT
Sbjct: 481 LYALRAITRHLT 492


>gi|7657437 sestrin 1 [Homo sapiens]
          Length = 551

 Score =  613 bits (1580), Expect = e-175
 Identities = 297/466 (63%), Positives = 371/466 (79%), Gaps = 14/466 (3%)

Query: 30  IRVSQPLTRGPSAFIPEKEVVQANTVDERTNFL-VEEYSTSGRLDNITQVMSLHTQYLES 88
           IR+ +PL +GPS FIPEKE++Q  + D + + L  + ++  GRLDNIT VM  H QYLES
Sbjct: 97  IRIPRPLGQGPSRFIPEKEILQVGSEDAQMHALFADSFAALGRLDNITLVMVFHPQYLES 156

Query: 89  FLRSQFYMLRMDGPLPLPYRHYIAIMAAARHQCSYLINMHVDEFLKTGGIAEWLNGLEYV 148
           FL++Q Y+L+MDGPLPL YRHYI IMAAARHQCSYL+N+HV++FL  GG  +WLNGLE  
Sbjct: 157 FLKTQHYLLQMDGPLPLHYRHYIGIMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENA 216

Query: 149 PQRLKNLNEINKLLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHYHALASFVF 208
           PQ+L+NL E+NK+LAHRPWLITKEHI+ L+K  E++WSL ELVHAVVLL HYH+LASF F
Sbjct: 217 PQKLQNLGELNKVLAHRPWLITKEHIEGLLKAEEHSWSLAELVHAVVLLTHYHSLASFTF 276

Query: 209 GSGINPERDPEISNGFRLISVNNFCVCDLANDNNI--ENASLSGSNFGIVDSLSELEALM 266
           G GI+PE   +  + FR  SV+N+C+CD+ N N+   E    S  N  + DS  E+EALM
Sbjct: 277 GCGISPEIHCDGGHTFRPPSVSNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALM 336

Query: 267 ERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIITSDVSR 326
           E+M++LQE R++EEASQEEM++RFE EK+ES+FV S D          ++++     VSR
Sbjct: 337 EKMRQLQECRDEEEASQEEMASRFEIEKRESMFVFSSD----------DEEVTPARAVSR 386

Query: 327 YIEDPGFGYEDFARRGEEHLPTFRAQDYTWENHGFSLVNRLYSDIGHLLDEKFRMVYNLT 386
           + ED  +GY+DF+R G  H+PTFR QDY WE+HG+SLVNRLY D+G L+DEKF + YNLT
Sbjct: 387 HFEDTSYGYKDFSRHGM-HVPTFRVQDYCWEDHGYSLVNRLYPDVGQLIDEKFHIAYNLT 445

Query: 387 YNTMATHEDVDTTMLRRALFNYVHCMFGIRYDDYDYGEVNQLLERSLKVYIKTVTCYPER 446
           YNTMA H+DVDT+MLRRA++NY+HCMFGIRYDDYDYGE+NQLL+RS KVYIKTV C PE+
Sbjct: 446 YNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDYDYGEINQLLDRSFKVYIKTVVCTPEK 505

Query: 447 TTKRMYDSYWRQFKHSEKVHVNLLLMEARMQAELLYALRAITRHLT 492
            TKRMYDS+WRQFKHSEKVHVNLLL+EARMQAELLYALRAITR++T
Sbjct: 506 VTKRMYDSFWRQFKHSEKVHVNLLLIEARMQAELLYALRAITRYMT 551


>gi|13899299 sestrin 2 [Homo sapiens]
          Length = 480

 Score =  518 bits (1333), Expect = e-147
 Identities = 265/457 (57%), Positives = 329/457 (71%), Gaps = 20/457 (4%)

Query: 38  RGPSAFIPEKEVVQANTVDERTNFLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYML 97
           RGPSAFIP +EV++        +  +E   +SGR+DN+  VM LH  Y  SF R  + +L
Sbjct: 42  RGPSAFIPVEEVLREGAESLEQHLGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLLL 101

Query: 98  RMDGPLPLPYRHYIAIMAAARHQCSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLKNLNE 157
             DGPL   +RHYIAIMAAARHQCSYL+  H+ EFL+TGG  EWL GL   P++L+ L+E
Sbjct: 102 HTDGPLASSWRHYIAIMAAARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLSE 161

Query: 158 INKLLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHYHALASFVFGSGINPERD 217
           INKLLAHRPWLITKEHIQ L+KTGE+ WSL EL+ A+VLL H H+L+SFVFG GI PE D
Sbjct: 162 INKLLAHRPWLITKEHIQALLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILPEGD 221

Query: 218 PEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEALMERMKRLQEE-R 276
            + S   +  +          ++ +   +    +N G  +S  ++EALMERM++LQE   
Sbjct: 222 ADGSPAPQAPTP--------PSEQSSPPSRDPLNNSGGFESARDVEALMERMQQLQESLL 273

Query: 277 EDEEASQEEMSTRFEKEKKESLFVV-SGDTFHSFPHSDFEDDMIITSDVSRYIEDPGFGY 335
            DE  SQEEM +RFE EK ESL V  S D     PH           D+  ++EDP FGY
Sbjct: 274 RDEGTSQEEMESRFELEKSESLLVTPSADILEPSPH----------PDMLCFVEDPTFGY 323

Query: 336 EDFARRGEEHLPTFRAQDYTWENHGFSLVNRLYSDIGHLLDEKFRMVYNLTYNTMATHED 395
           EDF RRG +  PTFRAQDYTWE+HG+SL+ RLY + G LLDEKF+  Y+LTYNT+A H  
Sbjct: 324 EDFTRRGAQAPPTFRAQDYTWEDHGYSLIQRLYPEGGQLLDEKFQAAYSLTYNTIAMHSG 383

Query: 396 VDTTMLRRALFNYVHCMFGIRYDDYDYGEVNQLLERSLKVYIKTVTCYPERTTKRMYDSY 455
           VDT++LRRA++NY+HC+FGIRYDDYDYGEVNQLLER+LKVYIKTV CYPE+TT+RMY+ +
Sbjct: 384 VDTSVLRRAIWNYIHCVFGIRYDDYDYGEVNQLLERNLKVYIKTVACYPEKTTRRMYNLF 443

Query: 456 WRQFKHSEKVHVNLLLMEARMQAELLYALRAITRHLT 492
           WR F+HSEKVHVNLLL+EARMQA LLYALRAITR++T
Sbjct: 444 WRHFRHSEKVHVNLLLLEARMQAALLYALRAITRYMT 480


>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
           isoform b [Homo sapiens]
          Length = 1176

 Score = 37.4 bits (85), Expect = 0.031
 Identities = 18/40 (45%), Positives = 26/40 (65%)

Query: 257 DSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKE 296
           DS SE+EAL E++   +EE E+EE  +EE     E+E+ E
Sbjct: 286 DSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDE 325


>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
           isoform a [Homo sapiens]
          Length = 1210

 Score = 37.4 bits (85), Expect = 0.031
 Identities = 18/40 (45%), Positives = 26/40 (65%)

Query: 257 DSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKE 296
           DS SE+EAL E++   +EE E+EE  +EE     E+E+ E
Sbjct: 286 DSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDE 325


>gi|45643129 guanine nucleotide binding protein-like 3 isoform 2
           [Homo sapiens]
          Length = 537

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 44/161 (27%), Positives = 67/161 (41%), Gaps = 10/161 (6%)

Query: 145 LEYVPQRLKNLNEINKLLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHY-HAL 203
           L+Y     +N  E   +LA R  +  K  I  +    +  WS  E   A   LA+Y H  
Sbjct: 339 LKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWS--EWTGAS--LAYYCHPP 394

Query: 204 ASFVFGSGINPERDPEISNGFRL--ISVNNFCVCDLANDNNIENASL---SGSNFGIVDS 258
            S+      N     ++ +GF L  +  NN          ++ N+ L   SG   GI++ 
Sbjct: 395 TSWTPPPYFNESIVVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEE 454

Query: 259 LSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLF 299
               E L +R +R QEERED++ S +E       E    +F
Sbjct: 455 KDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMF 495


>gi|45643127 guanine nucleotide binding protein-like 3 isoform 2
           [Homo sapiens]
          Length = 537

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 44/161 (27%), Positives = 67/161 (41%), Gaps = 10/161 (6%)

Query: 145 LEYVPQRLKNLNEINKLLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHY-HAL 203
           L+Y     +N  E   +LA R  +  K  I  +    +  WS  E   A   LA+Y H  
Sbjct: 339 LKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWS--EWTGAS--LAYYCHPP 394

Query: 204 ASFVFGSGINPERDPEISNGFRL--ISVNNFCVCDLANDNNIENASL---SGSNFGIVDS 258
            S+      N     ++ +GF L  +  NN          ++ N+ L   SG   GI++ 
Sbjct: 395 TSWTPPPYFNESIVVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEE 454

Query: 259 LSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLF 299
               E L +R +R QEERED++ S +E       E    +F
Sbjct: 455 KDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMF 495


>gi|45593130 guanine nucleotide binding protein-like 3 isoform 1
           [Homo sapiens]
          Length = 549

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 44/161 (27%), Positives = 67/161 (41%), Gaps = 10/161 (6%)

Query: 145 LEYVPQRLKNLNEINKLLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHY-HAL 203
           L+Y     +N  E   +LA R  +  K  I  +    +  WS  E   A   LA+Y H  
Sbjct: 351 LKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWS--EWTGAS--LAYYCHPP 406

Query: 204 ASFVFGSGINPERDPEISNGFRL--ISVNNFCVCDLANDNNIENASL---SGSNFGIVDS 258
            S+      N     ++ +GF L  +  NN          ++ N+ L   SG   GI++ 
Sbjct: 407 TSWTPPPYFNESIVVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEE 466

Query: 259 LSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLF 299
               E L +R +R QEERED++ S +E       E    +F
Sbjct: 467 KDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMF 507


>gi|6631095 minichromosome maintenance complex component 3 [Homo
           sapiens]
          Length = 808

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 3/60 (5%)

Query: 262 LEALMERMKRLQEERE---DEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDM 318
           LE   +R KR ++E E   +EE SQE+   + ++ K        GD++  +  SD E++M
Sbjct: 658 LEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEM 717


>gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]
          Length = 1507

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 17/107 (15%)

Query: 215  ERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEALMERMKRLQE 274
            + D + ++    +  +     +L  D+N ENA   G N        +     E +  L E
Sbjct: 1415 DEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDN--------DFSPSDEELANLLE 1466

Query: 275  EREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIIT 321
            E ED E          + +  E + ++ GDT  S  +SD EDD+I++
Sbjct: 1467 EGEDGEDE--------DSDADEEVELILGDT-DSSDNSDLEDDIILS 1504


>gi|131889097 cancer susceptibility candidate 1 isoform b [Homo
           sapiens]
          Length = 716

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 267 ERMKRLQEEREDEEASQEEMSTRFEKEKKESLFV--VSGDTFHSFPHSDFE 315
           ER+K LQEE E     +EE   ++EKE+ E L +  +  + +H     D E
Sbjct: 13  ERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLE 63


>gi|131889447 cancer susceptibility candidate 1 isoform c [Homo
           sapiens]
          Length = 690

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 267 ERMKRLQEEREDEEASQEEMSTRFEKEKKESLFV--VSGDTFHSFPHSDFE 315
           ER+K LQEE E     +EE   ++EKE+ E L +  +  + +H     D E
Sbjct: 77  ERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLE 127


>gi|131888105 cancer susceptibility candidate 1 isoform a [Homo
           sapiens]
          Length = 722

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 267 ERMKRLQEEREDEEASQEEMSTRFEKEKKESLFV--VSGDTFHSFPHSDFE 315
           ER+K LQEE E     +EE   ++EKE+ E L +  +  + +H     D E
Sbjct: 19  ERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLE 69


>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
          Length = 681

 Score = 33.1 bits (74), Expect = 0.59
 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 9/80 (11%)

Query: 259 LSELEALMERMKRLQEEREDEEASQEEMSTRFE----KEKKESLF----VVSGDTFHSFP 310
           LSE+EA +E +++ +EER+D+   +EE    FE     E +  LF    + SG +  +  
Sbjct: 207 LSEMEAYLENIEK-EEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLK 265

Query: 311 HSDFEDDMIITSDVSRYIED 330
           + DF D +    D++   +D
Sbjct: 266 YKDFFDPVESDEDITNVHDD 285


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 33.1 bits (74), Expect = 0.59
 Identities = 25/84 (29%), Positives = 36/84 (42%)

Query: 240  DNNIENASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLF 299
            + + +    SGSN    DS  E E   E  +  QE+ E EE  +++     E E  E   
Sbjct: 2413 EEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYP 2472

Query: 300  VVSGDTFHSFPHSDFEDDMIITSD 323
             ++      F   D EDD+II  D
Sbjct: 2473 DMNASPLVRFERFDREDDLIIEFD 2496


>gi|149192855 HLA-B associated transcript 2-like [Homo sapiens]
          Length = 2229

 Score = 33.1 bits (74), Expect = 0.59
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 19/99 (19%)

Query: 265  LMERMKRLQEEREDEEASQE--EMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIITS 322
            +++ +K   +E+E E+  QE  E STR  KEK++S      +        D E+D  + +
Sbjct: 946  VLKALKVEDKEKELEKIKQELGEESTRLAKEKEQSPTAEKDE--------DEENDASLAN 997

Query: 323  DVSRYIEDPGFGYEDFARRG----EEHLPTFRAQDYTWE 357
              +  +ED G G+  F R      EE  P     D  WE
Sbjct: 998  SSTTTLEDKGPGHATFGREATKFEEEEKP-----DKAWE 1031


>gi|147903302 MAP7 domain containing 3 [Homo sapiens]
          Length = 876

 Score = 32.7 bits (73), Expect = 0.77
 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 2/62 (3%)

Query: 237 LANDNNIENASLSGSNFGIVDSLSELEALME--RMKRLQEEREDEEASQEEMSTRFEKEK 294
           L+  + I   S + S  GI+++ +  + L E  R+ R Q E+E+EE  +EEM  R  K+ 
Sbjct: 575 LSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKS 634

Query: 295 KE 296
           K+
Sbjct: 635 KD 636


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 4/52 (7%)

Query: 246  ASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKES 297
            +SLSG N  + D    LEA   R+ +L+EE E+E+ + E MS R  K  +++
Sbjct: 1719 SSLSGRN-ALQDEKRRLEA---RIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 19/51 (37%), Positives = 27/51 (52%)

Query: 245  NASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKK 295
            N  LS S   + D  S +EAL E  KR Q+E E+     EE +  ++K +K
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1420


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 4/52 (7%)

Query: 246  ASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKES 297
            +SLSG N  + D    LEA   R+ +L+EE E+E+ + E MS R  K  +++
Sbjct: 1726 SSLSGRN-ALQDEKRRLEA---RIAQLEEELEEEQGNMEAMSDRVRKATQQA 1773



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 19/51 (37%), Positives = 27/51 (52%)

Query: 245  NASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKK 295
            N  LS S   + D  S +EAL E  KR Q+E E+     EE +  ++K +K
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1427


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 4/52 (7%)

Query: 246  ASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKES 297
            +SLSG N  + D    LEA   R+ +L+EE E+E+ + E MS R  K  +++
Sbjct: 1726 SSLSGRN-ALQDEKRRLEA---RIAQLEEELEEEQGNMEAMSDRVRKATQQA 1773



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 19/51 (37%), Positives = 27/51 (52%)

Query: 245  NASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKK 295
            N  LS S   + D  S +EAL E  KR Q+E E+     EE +  ++K +K
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1427


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 4/52 (7%)

Query: 246  ASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKES 297
            +SLSG N  + D    LEA   R+ +L+EE E+E+ + E MS R  K  +++
Sbjct: 1719 SSLSGRN-ALQDEKRRLEA---RIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 19/51 (37%), Positives = 27/51 (52%)

Query: 245  NASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKK 295
            N  LS S   + D  S +EAL E  KR Q+E E+     EE +  ++K +K
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1420


>gi|18490978 intermediate filament family orphan isoform 2 [Homo
           sapiens]
          Length = 559

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 265 LMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDF---EDDMIIT 321
           L +R+  LQEE ++ +A QEE++ + E+ K E L V  G   ++    D    E  M + 
Sbjct: 269 LQDRVNELQEEAQEADACQEELALKVEQLKAE-LVVFKGLMSNNLSELDTKIQEKAMKVD 327

Query: 322 SDVSRYIE 329
            D+ R I+
Sbjct: 328 MDICRRID 335


>gi|89213250 intermediate filament family orphan isoform 4 [Homo
           sapiens]
          Length = 563

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 265 LMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDF---EDDMIIT 321
           L +R+  LQEE ++ +A QEE++ + E+ K E L V  G   ++    D    E  M + 
Sbjct: 269 LQDRVNELQEEAQEADACQEELALKVEQLKAE-LVVFKGLMSNNLSELDTKIQEKAMKVD 327

Query: 322 SDVSRYIE 329
            D+ R I+
Sbjct: 328 MDICRRID 335


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 31/141 (21%), Positives = 58/141 (41%), Gaps = 6/141 (4%)

Query: 206 FVFGSGINPERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEAL 265
           F  G G  P ++ ++     L  + +  + D     +   +S + S  G  +   E E  
Sbjct: 231 FELGDGRKPVKEEKMEERDLLSDLQD--ISDSERKTSSAESSSAESGSGSEEEEEEEEEE 288

Query: 266 MER---MKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIITS 322
            E     +  +EE E+EE  +EE  +  E+  ++S   VS +        + E+ +++  
Sbjct: 289 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 348

Query: 323 DVSRYIEDPGFGYEDFARRGE 343
           + SR+  D G   E     GE
Sbjct: 349 E-SRFDRDSGESEEAEEEVGE 368



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 257 DSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFED 316
           D L +LE   ER ++++E+++ E+  Q+E   R E+ +KE          H     D+ D
Sbjct: 154 DRLEQLERKRERERKMREQQK-EQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 212


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 31/141 (21%), Positives = 58/141 (41%), Gaps = 6/141 (4%)

Query: 206 FVFGSGINPERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEAL 265
           F  G G  P ++ ++     L  + +  + D     +   +S + S  G  +   E E  
Sbjct: 241 FELGDGRKPVKEEKMEERDLLSDLQD--ISDSERKTSSAESSSAESGSGSEEEEEEEEEE 298

Query: 266 MER---MKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIITS 322
            E     +  +EE E+EE  +EE  +  E+  ++S   VS +        + E+ +++  
Sbjct: 299 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 358

Query: 323 DVSRYIEDPGFGYEDFARRGE 343
           + SR+  D G   E     GE
Sbjct: 359 E-SRFDRDSGESEEAEEEVGE 378



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 257 DSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFED 316
           D L +LE   ER ++++E+++ E+  Q+E   R E+ +KE          H     D+ D
Sbjct: 164 DRLEQLERKRERERKMREQQK-EQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 222


>gi|82830424 gon-4-like isoform a [Homo sapiens]
          Length = 2240

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 10/69 (14%)

Query: 236  DLANDNNIENASLSGSNFGIVDSLSELEALMERMKRLQEERE-------DEEASQEEMST 288
            DL  D   E +S S  +   V S+ EL+  ME++  L  ER        +EE SQEE S 
Sbjct: 1467 DLTQDEEDEMSSASEES---VLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSE 1523

Query: 289  RFEKEKKES 297
              E+E++E+
Sbjct: 1524 PEEEEEEEA 1532


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 31/141 (21%), Positives = 58/141 (41%), Gaps = 6/141 (4%)

Query: 206 FVFGSGINPERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEAL 265
           F  G G  P ++ ++     L  + +  + D     +   +S + S  G  +   E E  
Sbjct: 232 FELGDGRKPVKEEKMEERDLLSDLQD--ISDSERKTSSAESSSAESGSGSEEEEEEEEEE 289

Query: 266 MER---MKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIITS 322
            E     +  +EE E+EE  +EE  +  E+  ++S   VS +        + E+ +++  
Sbjct: 290 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 349

Query: 323 DVSRYIEDPGFGYEDFARRGE 343
           + SR+  D G   E     GE
Sbjct: 350 E-SRFDRDSGESEEAEEEVGE 369



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 257 DSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFED 316
           D L +LE   ER ++++E+++ E+  Q+E   R E+ +KE          H     D+ D
Sbjct: 155 DRLEQLERKRERERKMREQQK-EQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 213


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 31/141 (21%), Positives = 58/141 (41%), Gaps = 6/141 (4%)

Query: 206 FVFGSGINPERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEAL 265
           F  G G  P ++ ++     L  + +  + D     +   +S + S  G  +   E E  
Sbjct: 241 FELGDGRKPVKEEKMEERDLLSDLQD--ISDSERKTSSAESSSAESGSGSEEEEEEEEEE 298

Query: 266 MER---MKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIITS 322
            E     +  +EE E+EE  +EE  +  E+  ++S   VS +        + E+ +++  
Sbjct: 299 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 358

Query: 323 DVSRYIEDPGFGYEDFARRGE 343
           + SR+  D G   E     GE
Sbjct: 359 E-SRFDRDSGESEEAEEEVGE 378



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 257 DSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFED 316
           D L +LE   ER ++++E+++ E+  Q+E   R E+ +KE          H     D+ D
Sbjct: 164 DRLEQLERKRERERKMREQQK-EQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 222


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 31/141 (21%), Positives = 58/141 (41%), Gaps = 6/141 (4%)

Query: 206 FVFGSGINPERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEAL 265
           F  G G  P ++ ++     L  + +  + D     +   +S + S  G  +   E E  
Sbjct: 209 FELGDGRKPVKEEKMEERDLLSDLQD--ISDSERKTSSAESSSAESGSGSEEEEEEEEEE 266

Query: 266 MER---MKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIITS 322
            E     +  +EE E+EE  +EE  +  E+  ++S   VS +        + E+ +++  
Sbjct: 267 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 326

Query: 323 DVSRYIEDPGFGYEDFARRGE 343
           + SR+  D G   E     GE
Sbjct: 327 E-SRFDRDSGESEEAEEEVGE 346



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 257 DSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFED 316
           D L +LE   ER ++++E+++ E+  Q+E   R E+ +KE          H     D+ D
Sbjct: 132 DRLEQLERKRERERKMREQQK-EQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 190


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 31/141 (21%), Positives = 58/141 (41%), Gaps = 6/141 (4%)

Query: 206 FVFGSGINPERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEAL 265
           F  G G  P ++ ++     L  + +  + D     +   +S + S  G  +   E E  
Sbjct: 198 FELGDGRKPVKEEKMEERDLLSDLQD--ISDSERKTSSAESSSAESGSGSEEEEEEEEEE 255

Query: 266 MER---MKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIITS 322
            E     +  +EE E+EE  +EE  +  E+  ++S   VS +        + E+ +++  
Sbjct: 256 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 315

Query: 323 DVSRYIEDPGFGYEDFARRGE 343
           + SR+  D G   E     GE
Sbjct: 316 E-SRFDRDSGESEEAEEEVGE 335



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 257 DSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFED 316
           D L +LE   ER ++++E+++ E+  Q+E   R E+ +KE          H     D+ D
Sbjct: 121 DRLEQLERKRERERKMREQQK-EQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 179


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,203,670
Number of Sequences: 37866
Number of extensions: 806604
Number of successful extensions: 5630
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 5295
Number of HSP's gapped (non-prelim): 291
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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