Guide to the Human Genome
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Search of human proteins with 30840980

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]
         (498 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]              1027   0.0  
gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]              974   0.0  
gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens]              974   0.0  
gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]              955   0.0  
gi|56549649 nuclear factor I/X (CCAAT-binding transcription fact...   602   e-172
gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]               538   e-153
gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens]               512   e-145
gi|93004092 nuclear factor I/B [Homo sapiens]                         502   e-142
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             59   1e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    57   4e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    53   6e-07
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    52   1e-06
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    52   1e-06
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    52   1e-06
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    52   1e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    52   1e-06
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    52   1e-06
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             50   4e-06
gi|50345997 E1A binding protein p300 [Homo sapiens]                    49   8e-06
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               49   1e-05
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          49   1e-05
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          49   1e-05
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          49   1e-05
gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [...    48   2e-05
gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [...    48   2e-05
gi|124378039 SEC16 homolog A [Homo sapiens]                            48   2e-05
gi|47132519 Ras association and pleckstrin homology domains 1 is...    48   2e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    47   3e-05
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]        47   4e-05
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 47   5e-05

>gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]
          Length = 498

 Score = 1027 bits (2655), Expect = 0.0
 Identities = 498/498 (100%), Positives = 498/498 (100%)

Query: 1   MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60
           MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL
Sbjct: 1   MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60

Query: 61  LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120
           LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL
Sbjct: 61  LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120

Query: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180
           RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA
Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180

Query: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240
           YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT
Sbjct: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240

Query: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300
           GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS
Sbjct: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300

Query: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360
           PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS
Sbjct: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360

Query: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420
           PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN
Sbjct: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420

Query: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIK 480
           GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIK
Sbjct: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIK 480

Query: 481 VAASHHPPDRPPDPFSTL 498
           VAASHHPPDRPPDPFSTL
Sbjct: 481 VAASHHPPDRPPDPFSTL 498


>gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]
          Length = 554

 Score =  974 bits (2519), Expect = 0.0
 Identities = 477/494 (96%), Positives = 478/494 (96%)

Query: 1   MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60
           MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL
Sbjct: 46  MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 105

Query: 61  LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120
           LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL
Sbjct: 106 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 165

Query: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180
           RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA
Sbjct: 166 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 225

Query: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240
           YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT
Sbjct: 226 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 285

Query: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300
           GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS
Sbjct: 286 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 345

Query: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360
           PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS
Sbjct: 346 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 405

Query: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420
           PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN
Sbjct: 406 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 465

Query: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIK 480
           GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP       
Sbjct: 466 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 525

Query: 481 VAASHHPPDRPPDP 494
             A+      P DP
Sbjct: 526 SPANRFVSVGPRDP 539


>gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens]
          Length = 509

 Score =  974 bits (2519), Expect = 0.0
 Identities = 477/494 (96%), Positives = 478/494 (96%)

Query: 1   MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60
           MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL
Sbjct: 1   MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60

Query: 61  LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120
           LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL
Sbjct: 61  LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120

Query: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180
           RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA
Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180

Query: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240
           YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT
Sbjct: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240

Query: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300
           GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS
Sbjct: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300

Query: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360
           PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS
Sbjct: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360

Query: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420
           PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN
Sbjct: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420

Query: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIK 480
           GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP       
Sbjct: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 480

Query: 481 VAASHHPPDRPPDP 494
             A+      P DP
Sbjct: 481 SPANRFVSVGPRDP 494


>gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]
          Length = 501

 Score =  955 bits (2469), Expect = 0.0
 Identities = 468/485 (96%), Positives = 469/485 (96%)

Query: 10  DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 69
           DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ
Sbjct: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 61

Query: 70  KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 129
           KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 62  KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 121

Query: 130 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 189
           DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS
Sbjct: 122 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 181

Query: 190 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 249
           QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL
Sbjct: 182 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 241

Query: 250 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 309
           ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG
Sbjct: 242 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 301

Query: 310 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 369
           WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH
Sbjct: 302 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 361

Query: 370 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 429
           FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN
Sbjct: 362 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 421

Query: 430 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPD 489
           PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP         A+     
Sbjct: 422 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 481

Query: 490 RPPDP 494
            P DP
Sbjct: 482 GPRDP 486


>gi|56549649 nuclear factor I/X (CCAAT-binding transcription factor)
           [Homo sapiens]
          Length = 441

 Score =  602 bits (1553), Expect = e-172
 Identities = 311/422 (73%), Positives = 350/422 (82%), Gaps = 13/422 (3%)

Query: 1   MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60
           MYSP CLTQDEFHPFIEALLPHVRAF+YTWFNLQARKRKYFKKHEKRMSK+EERAVKDEL
Sbjct: 1   MYSPYCLTQDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL 60

Query: 61  LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120
           L EKPE+KQKWASRLLAKLRKDIRPE+REDFVLT+TGKKPPCCVLSNPDQKGK+RRIDCL
Sbjct: 61  LGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCL 120

Query: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180
           RQADKVWRLDLVMVILFKGIPLESTDGERL KSPQCSNPGLCVQPHHIGV++KELDLYLA
Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLA 180

Query: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240
           YFVH  +S QS+S +Q  DADIK  P NGHL FQD FVTSGV++VTELVRVSQTP+A  +
Sbjct: 181 YFVHTPESGQSDSSNQQGDADIKPLP-NGHLSFQDCFVTSGVWNVTELVRVSQTPVATAS 239

Query: 241 GPNFSLSDLESSSYYSMSPGAM-RRSLPSTSSTSSTKRLKSVED-EMDSPGEEPFYTGQG 298
           GPNFSL+DLES SYY+++   + RRS+ S  STS+TKR KS++D EM+SP ++ FY G G
Sbjct: 240 GPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTG 299

Query: 299 RSPGSG-SQSSGW-HEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITG 356
           RSP +G SQSSGW ++V+ G   P +LKKS K  F S   SQ SS   AFT H  PV+ G
Sbjct: 300 RSPAAGSSQSSGWPNDVDAG---PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAG 356

Query: 357 PR-ASPHATPSTLHFPTSPIIQQPGPYFSHPAIRY---HPQETLKEFVQLVCPD-AGQQA 411
            R  SP AT S LHFP++ IIQQ  PYF+HP IRY   H Q++LKEFVQ VC D +GQ  
Sbjct: 357 VRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQAT 416

Query: 412 GQ 413
           GQ
Sbjct: 417 GQ 418


>gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]
          Length = 499

 Score =  538 bits (1385), Expect = e-153
 Identities = 306/500 (61%), Positives = 357/500 (71%), Gaps = 44/500 (8%)

Query: 10  DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 69
           DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL EKPEVKQ
Sbjct: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 61

Query: 70  KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 129
           KWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 62  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 121

Query: 130 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 189
           DLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYFV   D+ 
Sbjct: 122 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 181

Query: 190 QSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 247
           QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GTGPNFSL 
Sbjct: 182 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 241

Query: 248 DLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQGRSPGSG 304
           +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT    SP S 
Sbjct: 242 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT----SPSSP 297

Query: 305 SQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI---TGPRA 359
           + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI   +G   
Sbjct: 298 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIAVHSGIAR 356

Query: 360 SPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQQAGQV 414
           SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A QQ G +
Sbjct: 357 SPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPL 415

Query: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPP--PPMARPVPLPVPDTKPPTTSTEGGAASPTS 472
                NGS Q K+ +  L   ML PPPP  P +A P     P TKP TTS EGGA SPTS
Sbjct: 416 -----NGSGQLKMPSHCLSAQMLAPPPPGLPRLALP-----PATKPATTS-EGGATSPTS 464

Query: 473 PILVPGIKVAASHHPPDRPP 492
           P          S+ PPD  P
Sbjct: 465 P----------SYSPPDTSP 474


>gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens]
          Length = 428

 Score =  512 bits (1318), Expect = e-145
 Identities = 278/430 (64%), Positives = 325/430 (75%), Gaps = 21/430 (4%)

Query: 3   SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLS 62
           SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL 
Sbjct: 4   SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLG 63

Query: 63  EKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQ 122
           EKPEVKQKWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQ
Sbjct: 64  EKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQ 123

Query: 123 ADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYF 182
           ADKVWRLDLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYF
Sbjct: 124 ADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYF 183

Query: 183 VHAADSSQSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240
           V   D+ QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GT
Sbjct: 184 VRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGT 243

Query: 241 GPNFSLSDLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQ 297
           GPNFSL +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT  
Sbjct: 244 GPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT-- 301

Query: 298 GRSPGSGSQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI- 354
             SP S + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI 
Sbjct: 302 --SPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIA 358

Query: 355 --TGPRASPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDA 407
             +G   SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A
Sbjct: 359 VHSGIARSPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPA 417

Query: 408 GQQAGQVGFL 417
            QQ G   +L
Sbjct: 418 SQQPGPSWYL 427


>gi|93004092 nuclear factor I/B [Homo sapiens]
          Length = 420

 Score =  502 bits (1292), Expect = e-142
 Identities = 274/421 (65%), Positives = 313/421 (74%), Gaps = 22/421 (5%)

Query: 1   MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60
           MYSP+CLTQDEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSK+EERAVKDEL
Sbjct: 2   MYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL 61

Query: 61  LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120
           LSEKPE+KQKWASRLLAKLRKDIR EYREDFVLTVTGKK PCCVLSNPDQKGK+RRIDCL
Sbjct: 62  LSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCL 121

Query: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180
           RQADKVWRLDLVMVILFKGIPLESTDGERL+KSP C+NP LCVQPHHI VSVKELDL+LA
Sbjct: 122 RQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLA 181

Query: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240
           Y+V   DS QS SPS    A  K+ P  G+L  +DSFV SGVF+V+ELVRVS+TPI  GT
Sbjct: 182 YYVQEQDSGQSGSPSHNDPA--KNPP--GYL--EDSFVKSGVFNVSELVRVSRTPITQGT 235

Query: 241 GPNFSLSDLESSSYY-SMSPGA-MRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQG 298
           G NF + ++ S  YY  M+ G  ++RSL S  S+   K + S+++ M+      FY    
Sbjct: 236 GVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTI-SIDENMEPSPTGDFYPSPS 294

Query: 299 RSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR 358
            SP +GS++  WHE +  M SPTT+KK EK  FSS SP  +S   + F QHH P I G  
Sbjct: 295 -SPAAGSRT--WHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVA 351

Query: 359 ASPHAT-----PSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAG 408
            S  +T     PS L FPT  I+   P  YFSHP IRY    +PQ+TLK +V    P + 
Sbjct: 352 HSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSP 411

Query: 409 Q 409
           Q
Sbjct: 412 Q 412


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 98/369 (26%), Positives = 131/369 (35%), Gaps = 29/369 (7%)

Query: 141  PLESTDGERLVKSPQCSNPGLCVQPHHIGVSV----KELDLYLAYFVHAADSSQSESPSQ 196
            P   + G     SP   +PG  + P +   S     +    Y       + +S S SP+ 
Sbjct: 1567 PTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTS 1626

Query: 197  PSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYYS 256
            PS +            +     TS  +S T       +P  + T P++S +   S SY  
Sbjct: 1627 PSYSPTSPNYSPTSPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPSYSPT---SPSYSP 1680

Query: 257  MSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPG 316
             SP     S PS S TS +    S      SP   P  T    SP S S S       P 
Sbjct: 1681 TSPSYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSP--TSPSYSPTSPSYSPTSPSYSPT 1737

Query: 317  MPS--PTTLKKSEKSGF---SSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFP 371
             PS  PT+   S  S     +SPS S TS   +  + ++ P  T P  SP  +PS  + P
Sbjct: 1738 SPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTP--TSPNYSP-TSPS--YSP 1792

Query: 372  TSPIIQQPGPYFSHPAIRYHPQE-TLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 430
            TSP      P +S  + RY PQ  T         P +   +       P   S       
Sbjct: 1793 TSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPE 1852

Query: 431  FLPTPMLPPPPPPPMARPVPL--PVPDTKPPTT---STEGGAASPTSPILVPGIKVAASH 485
            + PT     P  P  +   P   P   T  PTT   S      SPTSP+  P     +  
Sbjct: 1853 YTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPT 1912

Query: 486  HPPDRPPDP 494
             P   P  P
Sbjct: 1913 SPTYSPTSP 1921



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 84/307 (27%), Positives = 107/307 (34%), Gaps = 37/307 (12%)

Query: 188  SSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 247
            +S S SP+ PS +            +     TS  +S T       +P  + T PN+S +
Sbjct: 1695 TSPSYSPTSPSYSPTSPSYSPTSPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPNYSPT 1751

Query: 248  DLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQS 307
               S +Y   SP     S PS S TS      S      SP   P  T    SP S S S
Sbjct: 1752 ---SPNYTPTSPSYSPTS-PSYSPTSPNYTPTSPNYSPTSPSYSP--TSPSYSPTSPSYS 1805

Query: 308  SGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPST 367
                   P   SPT    S     SSPS S TS   T  +  + P      +SP  TP++
Sbjct: 1806 PSSPRYTP--QSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSP------SSPEYTPTS 1857

Query: 368  LHF-PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 426
              + PTSP      P +S  +  Y P                    +    +P  S    
Sbjct: 1858 PKYSPTSPKYSPTSPKYSPTSPTYSPTTP-----------------KYSPTSPTYSPTSP 1900

Query: 427  VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHH 486
            V+ P  P    P  P      P   P   T  PT S +G   SPTSP   P     +   
Sbjct: 1901 VYTPTSPK-YSPTSPTYSPTSPKYSPTSPTYSPT-SPKGSTYSPTSPGYSPTSPTYSLTS 1958

Query: 487  PPDRPPD 493
            P   P D
Sbjct: 1959 PAISPDD 1965



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 80/314 (25%), Positives = 110/314 (35%), Gaps = 27/314 (8%)

Query: 188  SSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 247
            +S S SP+ PS +            +     TS  +S T       +P  + T P++S +
Sbjct: 1660 TSPSYSPTSPSYSPTSPSYSPTSPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1716

Query: 248  DLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQS 307
               S SY   SP     S PS S TS +    S      SP   P  T    SP S S S
Sbjct: 1717 ---SPSYSPTSPSYSPTS-PSYSPTSPSYSPTSPNYSPTSPNYTP--TSPSYSPTSPSYS 1770

Query: 308  SGWHEVEPGMP--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATP 365
                   P  P  SPT+   S  S   SP+    S     +T    P  T P +  ++  
Sbjct: 1771 PTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQS-PTYT-PSSPSYSPS 1828

Query: 366  STLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQG 425
            S  + PTSP      P +S  +  Y P            P     + +    +P  S   
Sbjct: 1829 SPSYSPTSPKYTPTSPSYSPSSPEYTPTS----------PKYSPTSPKYSPTSPKYSPTS 1878

Query: 426  KVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAA---SPTSPILVPGIKVA 482
              ++P  P    P  P      PV  P      PT+ T    +   SPTSP   P     
Sbjct: 1879 PTYSPTTPK-YSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKG 1937

Query: 483  ASHHPPDRPPDPFS 496
            +++ P      P S
Sbjct: 1938 STYSPTSPGYSPTS 1951



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 66/265 (24%), Positives = 92/265 (34%), Gaps = 43/265 (16%)

Query: 232  SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEE 291
            + TP   G  P +        S   M+PGA   S PS +S +S            SPG  
Sbjct: 1516 AMTPWNQGATPAYGAWSPSVGS--GMTPGAAGFS-PSAASDASGF----------SPGYS 1562

Query: 292  PFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHR 351
            P ++    SPGS   SS      P +PSP         G  SPS S TS       +   
Sbjct: 1563 PAWSPTPGSPGSPGPSS------PYIPSP--------GGAMSPSYSPTSPA----YEPRS 1604

Query: 352  PVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 411
            P    P++  ++  S  + PTSP      P +S  +  Y P            P     +
Sbjct: 1605 PGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSP----------TSPSYSPTS 1654

Query: 412  GQVGFLNPNGSSQGKVHNPFLP--TPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAAS 469
                  +P+ S     ++P  P  +P  P   P   +     P      P+ S    + S
Sbjct: 1655 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1714

Query: 470  PTSPILVPGIKVAASHHPPDRPPDP 494
            PTSP   P     +   P   P  P
Sbjct: 1715 PTSPSYSPTSPSYSPTSPSYSPTSP 1739



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 54/197 (27%), Positives = 75/197 (38%), Gaps = 23/197 (11%)

Query: 219  TSGVFSVTELVRVSQTPIAAGTGPNFSLSD---LESSSYYSMSPGAMRRSLPSTSSTSST 275
            TS  +S T       +P  + T P++S S       S  Y+ S  +   S PS S TS  
Sbjct: 1779 TSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPK 1838

Query: 276  KRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMP--SPTTLKKSEKSGFSS 333
                S      SP   P  T    SP S   S    +  P  P  SPTT K S     +S
Sbjct: 1839 YTPTSPSYSPSSPEYTP--TSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSP----TS 1892

Query: 334  PSPSQTSSLGTAFTQHHRPVI------------TGPRASPHATPSTLHFPTSPIIQQPGP 381
            P+ S TS + T  +  + P              T P  SP +   + + PTSP      P
Sbjct: 1893 PTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSP 1952

Query: 382  YFSHPAIRYHPQETLKE 398
             +S  +    P ++ +E
Sbjct: 1953 TYSLTSPAISPDDSDEE 1969


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 73/280 (26%), Positives = 102/280 (36%), Gaps = 36/280 (12%)

Query: 232 SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRR-SLPSTSSTSSTKRLKSVEDEMDSPGE 290
           S  P     GP  S+S     S    SP A RR S        +++ L S    + SP  
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254

Query: 291 E-PFYTGQGRSPGSGSQSS--GWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFT 347
             P   G  R+P   SQ    G   + P   +P     +   G  S SP  T S   A  
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ 314

Query: 348 QHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDA 407
               P +    A+PH++  T    T   +  P P  + P+++  P            P A
Sbjct: 315 SQAPPTLP---ATPHSSSLTCQLATPLPLAPPSPS-APPSLQTLPS-----------PPA 359

Query: 408 GQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGA 467
              +     L   GS   +  + FLP+P L P   PP   P  L +P  + P +     A
Sbjct: 360 TPPSQATTSL---GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP---A 413

Query: 468 ASPTSPILVPGIK---------VAASHHPPDRPP--DPFS 496
           + P SP+  P  +         + A   PP  PP   PFS
Sbjct: 414 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 453



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 71/282 (25%), Positives = 105/282 (37%), Gaps = 55/282 (19%)

Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 317
           SP A   S  +TS  S T  L++    + SP   P  T   ++P + +       + P  
Sbjct: 356 SPPATPPSQATTSLGSPT--LQATHSFLPSPPLSPLATPPPQAPPALA-------LPPLQ 406

Query: 318 PSPTTLKKSEKSGFSSPSPSQTSSLGT-----AFTQHHRPVI-------TGPRASPHATP 365
             P+       S  ++PSP   ++L        F+    P +         P  SP ATP
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466

Query: 366 ST----------LHFPTSPIIQQP------GPYFSHPAIRYHPQETLKEFVQLVCPDAGQ 409
            +          L  P SP    P       P  + P +   P +  K   Q   P A  
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ--APPALA 524

Query: 410 QAGQVGFLNPNGSSQGKVHNPFLPTPMLP------PPP--PPPMARPVPLPVPDTKPPTT 461
                   +P  S  G+   PF P+  LP      PPP  PP +A P+ L VP + P + 
Sbjct: 525 TPPLQALPSPPASFPGQA--PFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASP 581

Query: 462 STEGGAASPT----SPILVPGIKVAASHHPPDRPP-DPFSTL 498
           + +     PT    + +  P + +A +  PP  P   P STL
Sbjct: 582 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 623



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 54/231 (23%), Positives = 76/231 (32%), Gaps = 53/231 (22%)

Query: 300 SPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR- 358
           S G+   +SG     PG PSP   ++S  +G     P    S         RP   GPR 
Sbjct: 157 SAGARRDTSG---PTPGTPSPAMARRSRAAGTEVGLPRPAPS------ARPRPPTEGPRK 207

Query: 359 ----ASPHAT----------PST---LHFPTSPIIQQPGPYFSHPA-----------IRY 390
               AS H+T          PS    L  P S  +       S PA              
Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 267

Query: 391 HPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVP 450
           HP +   + +Q + P           + P          P   +P+  P P   +    P
Sbjct: 268 HPSQPKPKGLQALRPPQ---------VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318

Query: 451 LPVPDTKPPTTSTEGGAA----SPTSPILVPGIKVAASHHPPDRPPDPFST 497
             +P T   ++ T   A     +P SP   P ++   S  PP  PP   +T
Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS--PPATPPSQATT 367


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 78/307 (25%), Positives = 106/307 (34%), Gaps = 67/307 (21%)

Query: 232 SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRR-SLPSTSSTSSTKRLKSVEDEMDSPGE 290
           S  P     GP  S+S     S    SP A RR S        +++ L S    + SP  
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245

Query: 291 E-PFYTGQGRSPGSGSQSS--GWHEVEPGMPSPT------TLKKSEKSGFSSPSPSQ--- 338
             P   G  R+P   SQ    G   + P   +P        L     S  ++PSPS    
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305

Query: 339 ---------------------TSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQ 377
                                T+SLG+   Q     +  P  SP ATP     P +P   
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP----PQAP--- 358

Query: 378 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 437
              P  + P ++  P            P A      +   +P   +   VH   L  P  
Sbjct: 359 ---PALALPPLQAPPS-----------PPASPPLSPLATPSPQAPNALAVH--LLQAPFS 402

Query: 438 PPPPPP---PMARPVPLPV-PDTKPPTTSTEGGAAS----PTSPILVPGIKVAASHHPPD 489
           PPP PP   P + P   PV P   PP+ +    AA     P SP   P +  +A+  PP 
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT--PPP 460

Query: 490 RPPDPFS 496
           + P P +
Sbjct: 461 QAPPPLA 467



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 71/281 (25%), Positives = 99/281 (35%), Gaps = 40/281 (14%)

Query: 250 ESSSYYSMSPGAMRRS---LPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 306
           E+    ++S GA R +    P T S +  +R ++   E+  P   P    +  + G    
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 199

Query: 307 SSGWHEVEPGMPSPTTLKK-SEKSGFSSPSPSQTSSLGTAFTQHHR--PVITG-PRASPH 362
            S   E     PSP   ++ S   G   P+    SS  T  +   R  P   G PRA  H
Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 259

Query: 363 AT---PSTLHFPTSPIIQQP--------GPYFSHPAIRYHPQ-----ETLKEFVQLVCPD 406
            +   P  L     P +  P        GP  S P     P              L  P 
Sbjct: 260 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPP 319

Query: 407 AGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGG 466
           A   +     L   GS   +  + FLP+P L P   PP   P  L +P  + P +     
Sbjct: 320 ATPPSQATTSL---GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP--- 373

Query: 467 AASPTSPILVPGIK---------VAASHHPPDRPP--DPFS 496
           A+ P SP+  P  +         + A   PP  PP   PFS
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 71/282 (25%), Positives = 105/282 (37%), Gaps = 55/282 (19%)

Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 317
           SP A   S  +TS  S T  L++    + SP   P  T   ++P + +       + P  
Sbjct: 317 SPPATPPSQATTSLGSPT--LQATHSFLPSPPLSPLATPPPQAPPALA-------LPPLQ 367

Query: 318 PSPTTLKKSEKSGFSSPSPSQTSSLGT-----AFTQHHRPVI-------TGPRASPHATP 365
             P+       S  ++PSP   ++L        F+    P +         P  SP ATP
Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 427

Query: 366 ST----------LHFPTSPIIQQP------GPYFSHPAIRYHPQETLKEFVQLVCPDAGQ 409
            +          L  P SP    P       P  + P +   P +  K   Q   P A  
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ--APPALA 485

Query: 410 QAGQVGFLNPNGSSQGKVHNPFLPTPMLP------PPP--PPPMARPVPLPVPDTKPPTT 461
                   +P  S  G+   PF P+  LP      PPP  PP +A P+ L VP + P + 
Sbjct: 486 TPPLQALPSPPASFPGQA--PFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASP 542

Query: 462 STEGGAASPT----SPILVPGIKVAASHHPPDRPP-DPFSTL 498
           + +     PT    + +  P + +A +  PP  P   P STL
Sbjct: 543 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 584


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 50/161 (31%), Positives = 58/161 (36%), Gaps = 18/161 (11%)

Query: 334 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 393
           PS   TSSL  + T    P +  P   P         P  P   Q  P   HPA    P 
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387

Query: 394 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 453
                 VQ   P   + A     +  +   QG+V         LPPPPPPP     PLP 
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434

Query: 454 PDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPPDP 494
           P  +P +  T    A P S  L P    A   H P  PP P
Sbjct: 435 PGIRPSSPVTVTALAHPPSG-LHPTPSTAPGPHVPLMPPSP 474



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 27/93 (29%), Positives = 32/93 (34%), Gaps = 17/93 (18%)

Query: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 462
           G +     S      P   +P  PPPPPP             M    P PVP   PP  +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361

Query: 463 TEGGAASPTSPI---LVPGIKVAASHHPPDRPP 492
                A P  P    + PG+   A   PP  PP
Sbjct: 362 ALQAPAVPPPPAPLQIAPGVLHPAP--PPIAPP 392



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 6/62 (9%)

Query: 433 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPP 492
           P  + P PPPPP   P  L     +   TST      P  P+  P    A +   P  PP
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTST------PPPPVPPPPPPPATALQAPAVPP 370

Query: 493 DP 494
            P
Sbjct: 371 PP 372



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 24/79 (30%), Positives = 29/79 (36%), Gaps = 23/79 (29%)

Query: 439 PPPPPPM-----ARPVPLPVPDT--------KPPTTSTEGGAASPTSPILVPGIKVA--- 482
           PPPPPPM     A+P+P  +           + P T       SPT P   P +  A   
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337

Query: 483 -------ASHHPPDRPPDP 494
                   S  PP  PP P
Sbjct: 338 SSLRASMTSTPPPPVPPPP 356


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 50/161 (31%), Positives = 58/161 (36%), Gaps = 18/161 (11%)

Query: 334 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 393
           PS   TSSL  + T    P +  P   P         P  P   Q  P   HPA    P 
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387

Query: 394 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 453
                 VQ   P   + A     +  +   QG+V         LPPPPPPP     PLP 
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434

Query: 454 PDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPPDP 494
           P  +P +  T    A P S  L P    A   H P  PP P
Sbjct: 435 PGIRPSSPVTVTALAHPPSG-LHPTPSTAPGPHVPLMPPSP 474



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 27/93 (29%), Positives = 32/93 (34%), Gaps = 17/93 (18%)

Query: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 462
           G +     S      P   +P  PPPPPP             M    P PVP   PP  +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361

Query: 463 TEGGAASPTSPI---LVPGIKVAASHHPPDRPP 492
                A P  P    + PG+   A   PP  PP
Sbjct: 362 ALQAPAVPPPPAPLQIAPGVLHPAP--PPIAPP 392



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 6/62 (9%)

Query: 433 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPP 492
           P  + P PPPPP   P  L     +   TST      P  P+  P    A +   P  PP
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTST------PPPPVPPPPPPPATALQAPAVPP 370

Query: 493 DP 494
            P
Sbjct: 371 PP 372



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 24/79 (30%), Positives = 29/79 (36%), Gaps = 23/79 (29%)

Query: 439 PPPPPPM-----ARPVPLPVPDT--------KPPTTSTEGGAASPTSPILVPGIKVA--- 482
           PPPPPPM     A+P+P  +           + P T       SPT P   P +  A   
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337

Query: 483 -------ASHHPPDRPPDP 494
                   S  PP  PP P
Sbjct: 338 SSLRASMTSTPPPPVPPPP 356


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 50/161 (31%), Positives = 58/161 (36%), Gaps = 18/161 (11%)

Query: 334 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 393
           PS   TSSL  + T    P +  P   P         P  P   Q  P   HPA    P 
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387

Query: 394 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 453
                 VQ   P   + A     +  +   QG+V         LPPPPPPP     PLP 
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434

Query: 454 PDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPPDP 494
           P  +P +  T    A P S  L P    A   H P  PP P
Sbjct: 435 PGIRPSSPVTVTALAHPPSG-LHPTPSTAPGPHVPLMPPSP 474



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 27/93 (29%), Positives = 32/93 (34%), Gaps = 17/93 (18%)

Query: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 462
           G +     S      P   +P  PPPPPP             M    P PVP   PP  +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361

Query: 463 TEGGAASPTSPI---LVPGIKVAASHHPPDRPP 492
                A P  P    + PG+   A   PP  PP
Sbjct: 362 ALQAPAVPPPPAPLQIAPGVLHPAP--PPIAPP 392



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 6/62 (9%)

Query: 433 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPP 492
           P  + P PPPPP   P  L     +   TST      P  P+  P    A +   P  PP
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTST------PPPPVPPPPPPPATALQAPAVPP 370

Query: 493 DP 494
            P
Sbjct: 371 PP 372



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 24/79 (30%), Positives = 29/79 (36%), Gaps = 23/79 (29%)

Query: 439 PPPPPPM-----ARPVPLPVPDT--------KPPTTSTEGGAASPTSPILVPGIKVA--- 482
           PPPPPPM     A+P+P  +           + P T       SPT P   P +  A   
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337

Query: 483 -------ASHHPPDRPPDP 494
                   S  PP  PP P
Sbjct: 338 SSLRASMTSTPPPPVPPPP 356


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 50/161 (31%), Positives = 58/161 (36%), Gaps = 18/161 (11%)

Query: 334 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 393
           PS   TSSL  + T    P +  P   P         P  P   Q  P   HPA    P 
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387

Query: 394 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 453
                 VQ   P   + A     +  +   QG+V         LPPPPPPP     PLP 
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434

Query: 454 PDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPPDP 494
           P  +P +  T    A P S  L P    A   H P  PP P
Sbjct: 435 PGIRPSSPVTVTALAHPPSG-LHPTPSTAPGPHVPLMPPSP 474



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 27/93 (29%), Positives = 32/93 (34%), Gaps = 17/93 (18%)

Query: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 462
           G +     S      P   +P  PPPPPP             M    P PVP   PP  +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361

Query: 463 TEGGAASPTSPI---LVPGIKVAASHHPPDRPP 492
                A P  P    + PG+   A   PP  PP
Sbjct: 362 ALQAPAVPPPPAPLQIAPGVLHPAP--PPIAPP 392



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 6/62 (9%)

Query: 433 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPP 492
           P  + P PPPPP   P  L     +   TST      P  P+  P    A +   P  PP
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTST------PPPPVPPPPPPPATALQAPAVPP 370

Query: 493 DP 494
            P
Sbjct: 371 PP 372



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 24/79 (30%), Positives = 29/79 (36%), Gaps = 23/79 (29%)

Query: 439 PPPPPPM-----ARPVPLPVPDT--------KPPTTSTEGGAASPTSPILVPGIKVA--- 482
           PPPPPPM     A+P+P  +           + P T       SPT P   P +  A   
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337

Query: 483 -------ASHHPPDRPPDP 494
                   S  PP  PP P
Sbjct: 338 SSLRASMTSTPPPPVPPPP 356


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 56/229 (24%), Positives = 76/229 (33%), Gaps = 22/229 (9%)

Query: 288 PGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFT 347
           P   P   G+   P  G +S         MP P     S+      P PS    + ++  
Sbjct: 140 PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH 199

Query: 348 QHHRPVITGPRASPHATPSTLHFPTS--------PIIQQP----GPYFSHPAIRYHPQET 395
               P + G    P   P+   FP +         I Q P     P+ + P +   P   
Sbjct: 200 NRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259

Query: 396 LKEFVQLVCPDAGQQAG-QVGFLNPNGSSQGKVHNPFLPTPMLP---PPPPPPMARPVPL 451
           L +      P  G +       + P      K   P  P P      PPPPPP +RP P 
Sbjct: 260 LDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP 319

Query: 452 PVP------DTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPPDP 494
           P+P      D  P         +S T P+  PG        P +RPP P
Sbjct: 320 PLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 35/223 (15%)

Query: 288 PGEEPFYTGQGRSPGSGS-------QSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTS 340
           P   PF   +G + G GS        SS +    P  P+P+     +      P  ++ S
Sbjct: 217 PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPS 276

Query: 341 SLGTAFT----QHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETL 396
               A      Q+++P +    ++P  + S+   P  P   +PGP    P+   + +   
Sbjct: 277 IHREAVPPPPPQNNKPPVP---STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET-- 331

Query: 397 KEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPP----PPMARPVPLP 452
                   P   Q+   +    P   S G+   P  P P   PPPP    P  + P+P P
Sbjct: 332 --------PRLPQRNLSLSSSTPPLPSPGR-SGPLPPPPSERPPPPVRDPPGRSGPLPPP 382

Query: 453 VPDTKPPTTSTEGGAASPTSPILV--PGIKVAASHHPPDRPPD 493
            P ++  +TS     A P +P L    G+    S   P  PPD
Sbjct: 383 PPVSRNGSTS----RALPATPQLPSRSGVDSPRSGPRPPLPPD 421



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 37/153 (24%), Positives = 47/153 (30%), Gaps = 26/153 (16%)

Query: 315 PGMPSPTTLKKSEKSGFSSPS-PSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTS 373
           P  P P  L  S      +P  P +  SL ++      P +  P  S    P     P  
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS-----TPPLPSPGRSGPLPPPPSERPPP 367

Query: 374 PIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLP 433
           P+   PG     P     P  +         P   Q   + G  +P             P
Sbjct: 368 PVRDPPGRSGPLPP---PPPVSRNGSTSRALPATPQLPSRSGVDSPRSG----------P 414

Query: 434 TPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGG 466
            P LPP  P   A P P       PP+TS   G
Sbjct: 415 RPPLPPDRPSAGAPPPP-------PPSTSIRNG 440


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 56/229 (24%), Positives = 76/229 (33%), Gaps = 22/229 (9%)

Query: 288 PGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFT 347
           P   P   G+   P  G +S         MP P     S+      P PS    + ++  
Sbjct: 140 PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH 199

Query: 348 QHHRPVITGPRASPHATPSTLHFPTS--------PIIQQP----GPYFSHPAIRYHPQET 395
               P + G    P   P+   FP +         I Q P     P+ + P +   P   
Sbjct: 200 NRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259

Query: 396 LKEFVQLVCPDAGQQAG-QVGFLNPNGSSQGKVHNPFLPTPMLP---PPPPPPMARPVPL 451
           L +      P  G +       + P      K   P  P P      PPPPPP +RP P 
Sbjct: 260 LDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP 319

Query: 452 PVP------DTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPPDP 494
           P+P      D  P         +S T P+  PG        P +RPP P
Sbjct: 320 PLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 35/223 (15%)

Query: 288 PGEEPFYTGQGRSPGSGS-------QSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTS 340
           P   PF   +G + G GS        SS +    P  P+P+     +      P  ++ S
Sbjct: 217 PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPS 276

Query: 341 SLGTAFT----QHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETL 396
               A      Q+++P +    ++P  + S+   P  P   +PGP    P+   + +   
Sbjct: 277 IHREAVPPPPPQNNKPPVP---STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET-- 331

Query: 397 KEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPP----PPMARPVPLP 452
                   P   Q+   +    P   S G+   P  P P   PPPP    P  + P+P P
Sbjct: 332 --------PRLPQRNLSLSSSTPPLPSPGR-SGPLPPPPSERPPPPVRDPPGRSGPLPPP 382

Query: 453 VPDTKPPTTSTEGGAASPTSPILV--PGIKVAASHHPPDRPPD 493
            P ++  +TS     A P +P L    G+    S   P  PPD
Sbjct: 383 PPVSRNGSTS----RALPATPQLPSRSGVDSPRSGPRPPLPPD 421



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 37/153 (24%), Positives = 47/153 (30%), Gaps = 26/153 (16%)

Query: 315 PGMPSPTTLKKSEKSGFSSPS-PSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTS 373
           P  P P  L  S      +P  P +  SL ++      P +  P  S    P     P  
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS-----TPPLPSPGRSGPLPPPPSERPPP 367

Query: 374 PIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLP 433
           P+   PG     P     P  +         P   Q   + G  +P             P
Sbjct: 368 PVRDPPGRSGPLPP---PPPVSRNGSTSRALPATPQLPSRSGVDSPRSG----------P 414

Query: 434 TPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGG 466
            P LPP  P   A P P       PP+TS   G
Sbjct: 415 RPPLPPDRPSAGAPPPP-------PPSTSIRNG 440


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 62/266 (23%), Positives = 95/266 (35%), Gaps = 28/266 (10%)

Query: 240  TGPNFSLSDLESSSYYSMSPGAMRRSLPS-----TSSTSSTKRLKSVEDEMDSPGEEPFY 294
            T P+F+LS  +SS   +++P      LP+     TS  S+   + S+    +   E    
Sbjct: 1065 TSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTT 1124

Query: 295  TGQGRSPGSGSQSSGWHEVEPG-MPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPV 353
                 +P S + S      +P   P PTT          + +P   ++L    T H  P 
Sbjct: 1125 PDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDP------TMAPDPITTLNPTVTPHF-PT 1177

Query: 354  ITGPRASPHATPST--LHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 411
               P  +PH T  T     P      QP    +H  +   P  T + F  +         
Sbjct: 1178 TPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHST 1237

Query: 412  GQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPT 471
                   P+ ++    H+  +P P   P P   M +P  +P P T P  T+T     +P 
Sbjct: 1238 TPHPTTTPHPTTI--THSTMIPDPTTTPQPFTTM-QPTTMPHPTTTPHPTTTPHPTTTP- 1293

Query: 472  SPILVPGIKVAASHHPPDRPPDPFST 497
             P   P          P   PDP +T
Sbjct: 1294 HPTTTP---------HPTMTPDPTTT 1310



 Score = 35.8 bits (81), Expect = 0.093
 Identities = 46/190 (24%), Positives = 66/190 (34%), Gaps = 35/190 (18%)

Query: 318  PSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQ 377
            P PTT      +   + +P  T++     T H  P    P ++P  T  T+  PTS   +
Sbjct: 1293 PHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPH--PTTPDPSSTPVIT--TVSLPTSLGTE 1348

Query: 378  QPGPYFSHPAIR--YHPQETLKEFVQLVCPDAGQQAGQVGFL--------NPNGSSQGKV 427
               P  + P ++   HPQ T         P       Q+  L        +P+ SS    
Sbjct: 1349 LSSPTLA-PTVKPSLHPQLTF------TAPAPHTSTSQIPTLEPSPALESSPSRSSTATS 1401

Query: 428  HNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHP 487
             +P       PP    P   P P   P +    T +     SPT+             HP
Sbjct: 1402 MDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTA-------------HP 1448

Query: 488  PDRPP-DPFS 496
             D PP DP +
Sbjct: 1449 LDHPPLDPLT 1458


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 52/169 (30%), Positives = 66/169 (39%), Gaps = 19/169 (11%)

Query: 300 SPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRA 359
           SP     S G H   P +P P   + S      SP PS+T       T HH P   G + 
Sbjct: 805 SPIMPPGSQGSHIHCPQLPQPALHQNSP-----SPVPSRTP------TPHHTPPSIGAQQ 853

Query: 360 SPHATPSTLHFPTSPIIQQPGPYFS--HPAIRYHPQETLKEFVQLVCPD--AGQQAGQVG 415
            P AT      PT P +  PGP     HP  R  P     +  Q V P   A   A Q  
Sbjct: 854 PP-ATTIPAPVPTPPAMP-PGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQ 911

Query: 416 FLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP-VPLPVPDTKPPTTST 463
              P          P    P+LPP P  P+++P V +    + PP+TS+
Sbjct: 912 -QQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSS 959



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 59/227 (25%), Positives = 86/227 (37%), Gaps = 34/227 (14%)

Query: 291 EPFYTGQGRSPG-SGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPS--PSQTSSLGTAFT 347
           +P  T  G  P  S  + S  +++ P +   + L +  +   + P   P QT  L     
Sbjct: 679 QPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPL----- 733

Query: 348 QHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDA 407
           QHH     G  A P A    + +   P +QQP            P + +      + P +
Sbjct: 734 QHH-----GQLAQPGALNPPMGY--GPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSS 786

Query: 408 GQQAGQVGFLN-----------PNGSSQGKVHNPFLPTPMLPP--PPPPPMARPVPLPVP 454
           GQ       ++           P GS    +H P LP P L    P P P   P P   P
Sbjct: 787 GQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTP 846

Query: 455 DT----KPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPPDPFST 497
            +    +PP T+    A  PT P + PG +  A H PP + P P +T
Sbjct: 847 PSIGAQQPPATTIP--APVPTPPAMPPGPQSQALHPPPRQTPTPPTT 891



 Score = 32.7 bits (73), Expect = 0.78
 Identities = 32/95 (33%), Positives = 40/95 (42%), Gaps = 11/95 (11%)

Query: 353  VITGPRASPHATPSTLHFPTSPIIQQPG-PYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 411
            V+   +  P  TP+T   PT+P  QQP  P    P  +  PQ T    +    P   Q A
Sbjct: 1840 VVGQQQGLPSPTPAT---PTTPTGQQPTTPQTPQPTSQ--PQPTPPNSMPPYLPRT-QAA 1893

Query: 412  GQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMA 446
            G V      G + G+V  P  P    PP P PP A
Sbjct: 1894 GPVS----QGKAAGQVTPPTPPQTAQPPLPGPPPA 1924


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 68/244 (27%), Positives = 88/244 (36%), Gaps = 62/244 (25%)

Query: 267 PSTSSTSSTKRLKSVEDEMDSP----GEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTT 322
           P  +S S   RL  ++D+  +P      +PF+ G    P   S         P  P P T
Sbjct: 432 PVPNSFSQPPRLP-LQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPT 490

Query: 323 LKKSEKSGFSSPSPSQT----SSLGTAFTQH-HRPVITGPRASPHATPSTLHFPTSPIIQ 377
           L  S     S P P+Q+    +  G AF Q   +PV    R            P  P +Q
Sbjct: 491 LLNS-----SHPVPTQSPLPFTQPGPAFNQQGQQPVFPRER------------PVRPALQ 533

Query: 378 QPGP----YFSHPAIRYHPQETLKEFV---QLVCPDAGQQAGQVGFL--NPNGSSQGKVH 428
            PGP    +FS P        T + F+   Q   P  GQ      FL  +   + QG +H
Sbjct: 534 PPGPVGILHFSQPG-----SATTRPFIPPRQPFLPGPGQP-----FLPTHTQPNLQGPLH 583

Query: 429 NPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPP 488
            P      LPPP  P   +P   P P  +PP          P  P   P        HPP
Sbjct: 584 PP------LPPPHQPQPQQPQQQPPPQHQPP-------HQPPHQP---PPQHQPPPQHPP 627

Query: 489 DRPP 492
             PP
Sbjct: 628 QHPP 631



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 48/160 (30%), Positives = 60/160 (37%), Gaps = 27/160 (16%)

Query: 343 GTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQ--PGPY---FSHPAIRYHPQETLK 397
           GT  T    P++  P + P        FP  P   Q  PGP    FS P     P+  L+
Sbjct: 393 GTVVTPVQVPLLPVP-SQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQP-----PRLPLQ 446

Query: 398 EFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPP----MARPVPL-- 451
           +  Q   P   Q      FL  +G  +   H  FL     PPPPPPP     + PVP   
Sbjct: 447 D--QWRAPPPPQDRDPF-FLGVSGEPRFPSHL-FLEQRSPPPPPPPPTLLNSSHPVPTQS 502

Query: 452 PVPDTKPPTTSTEGG------AASPTSPILVPGIKVAASH 485
           P+P T+P     + G         P  P L P   V   H
Sbjct: 503 PLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILH 542



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 31/111 (27%), Positives = 41/111 (36%), Gaps = 31/111 (27%)

Query: 385 HPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKV--HNP-FLPT-----PM 436
           H   RY  +   +    L+C   G Q  +        + +G++  H P  LPT     P 
Sbjct: 266 HKQGRYSSRRGGRRGGPLMCRGVGDQRRE-------STERGRMKDHRPALLPTQPPVVPQ 318

Query: 437 LPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHP 487
            PPPPPPP   P   P+     P          P  P+L     V   HHP
Sbjct: 319 APPPPPPP---PQQQPIRSLFQP---------QPLQPLL----PVQHPHHP 353


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 74/292 (25%), Positives = 102/292 (34%), Gaps = 57/292 (19%)

Query: 225 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 282
           + E +R S   +P AA T  N S ++    S   +   A   S P  S+    +++ S  
Sbjct: 48  INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 104

Query: 283 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 336
           +E D    +   T +   P S S+  G         + G   P  + +  +S   S PSP
Sbjct: 105 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 164

Query: 337 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 388
                   SS      Q   P +   TG   +P + P     P +P +  PGP  S  A+
Sbjct: 165 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 219

Query: 389 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 448
              PQ +         P A Q   Q     P   +    H      P L P  PP    P
Sbjct: 220 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 260

Query: 449 VPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPP----DRPPDPFS 496
            P P P   PP     G A  P++P          SH  P      PP P S
Sbjct: 261 HPPPHPSPHPPLQPLTGSAGQPSAP----------SHAQPPLHGQGPPGPHS 302



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 69/283 (24%), Positives = 90/283 (31%), Gaps = 35/283 (12%)

Query: 242 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 301
           P  + SD +SS+   M           T  T +         ++ +PG  P  T     P
Sbjct: 164 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 220

Query: 302 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSL----GTAF 346
             GS ++     +P  P+           P    +   S    P PS    L    G+A 
Sbjct: 221 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA- 279

Query: 347 TQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY--FSHPAIRYHPQETLKEFVQLVC 404
            Q   P    P       P        P++Q PGP   F  P      Q  L        
Sbjct: 280 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 339

Query: 405 PDAGQQ--AGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVP-LPVPDTK--PP 459
           P    Q  A Q        S Q     P  P P+  P   PP   P+P LP P     PP
Sbjct: 340 PHTSLQLPASQSALQ----SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP 395

Query: 460 TTSTEG----GAASPTSPILVPGIKVAASHHPPDRPPDPFSTL 498
             S        A  P  P L P +   ++HHPP   P P   +
Sbjct: 396 HLSGPSPFSMNANLPPPPALKP-LSSLSTHHPPSAHPPPLQLM 437



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 65/276 (23%), Positives = 87/276 (31%), Gaps = 75/276 (27%)

Query: 291 EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 336
           +P   GQG  PG  S  +G     PG P P  L      G +    SP+          P
Sbjct: 289 QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 347

Query: 337 SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-------------F 383
           +  S+L +      +P+   P A PH  P     PT+PI Q P P              F
Sbjct: 348 ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 403

Query: 384 S--------------------HPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLN----- 418
           S                    HP   + P   L    Q +     Q  G     N     
Sbjct: 404 SMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 463

Query: 419 ----PNGSSQGKVHNPFLPTPMLP-------PPPPPPMARPVPLPVPDTKPPTT------ 461
               P G  Q     PF   P +P       PP  P  + P   P    +PP +      
Sbjct: 464 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 523

Query: 462 -STEGGAASPTSPILVPGIKVAASHHPPDRPPDPFS 496
            S  GG++ P   + +    +  +  P   PP P S
Sbjct: 524 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRS 559


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 74/292 (25%), Positives = 102/292 (34%), Gaps = 57/292 (19%)

Query: 225 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 282
           + E +R S   +P AA T  N S ++    S   +   A   S P  S+    +++ S  
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 658

Query: 283 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 336
           +E D    +   T +   P S S+  G         + G   P  + +  +S   S PSP
Sbjct: 659 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 718

Query: 337 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 388
                   SS      Q   P +   TG   +P + P     P +P +  PGP  S  A+
Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 773

Query: 389 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 448
              PQ +         P A Q   Q     P   +    H      P L P  PP    P
Sbjct: 774 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 814

Query: 449 VPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPP----DRPPDPFS 496
            P P P   PP     G A  P++P          SH  P      PP P S
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAP----------SHAQPPLHGQGPPGPHS 856



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 69/283 (24%), Positives = 90/283 (31%), Gaps = 35/283 (12%)

Query: 242 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 301
           P  + SD +SS+   M           T  T +         ++ +PG  P  T     P
Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 774

Query: 302 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSL----GTAF 346
             GS ++     +P  P+           P    +   S    P PS    L    G+A 
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA- 833

Query: 347 TQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY--FSHPAIRYHPQETLKEFVQLVC 404
            Q   P    P       P        P++Q PGP   F  P      Q  L        
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 893

Query: 405 PDAGQQ--AGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVP-LPVPDTK--PP 459
           P    Q  A Q        S Q     P  P P+  P   PP   P+P LP P     PP
Sbjct: 894 PHTSLQLPASQSALQ----SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP 949

Query: 460 TTSTEG----GAASPTSPILVPGIKVAASHHPPDRPPDPFSTL 498
             S        A  P  P L P +   ++HHPP   P P   +
Sbjct: 950 HLSGPSPFSMNANLPPPPALKP-LSSLSTHHPPSAHPPPLQLM 991



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 65/276 (23%), Positives = 87/276 (31%), Gaps = 75/276 (27%)

Query: 291  EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 336
            +P   GQG  PG  S  +G     PG P P  L      G +    SP+          P
Sbjct: 843  QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901

Query: 337  SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-------------F 383
            +  S+L +      +P+   P A PH  P     PT+PI Q P P              F
Sbjct: 902  ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 957

Query: 384  S--------------------HPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLN----- 418
            S                    HP   + P   L    Q +     Q  G     N     
Sbjct: 958  SMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017

Query: 419  ----PNGSSQGKVHNPFLPTPMLP-------PPPPPPMARPVPLPVPDTKPPTT------ 461
                P G  Q     PF   P +P       PP  P  + P   P    +PP +      
Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 1077

Query: 462  -STEGGAASPTSPILVPGIKVAASHHPPDRPPDPFS 496
             S  GG++ P   + +    +  +  P   PP P S
Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRS 1113


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 74/292 (25%), Positives = 102/292 (34%), Gaps = 57/292 (19%)

Query: 225 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 282
           + E +R S   +P AA T  N S ++    S   +   A   S P  S+    +++ S  
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 658

Query: 283 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 336
           +E D    +   T +   P S S+  G         + G   P  + +  +S   S PSP
Sbjct: 659 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 718

Query: 337 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 388
                   SS      Q   P +   TG   +P + P     P +P +  PGP  S  A+
Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 773

Query: 389 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 448
              PQ +         P A Q   Q     P   +    H      P L P  PP    P
Sbjct: 774 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 814

Query: 449 VPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPP----DRPPDPFS 496
            P P P   PP     G A  P++P          SH  P      PP P S
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAP----------SHAQPPLHGQGPPGPHS 856



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 69/283 (24%), Positives = 90/283 (31%), Gaps = 35/283 (12%)

Query: 242 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 301
           P  + SD +SS+   M           T  T +         ++ +PG  P  T     P
Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 774

Query: 302 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSL----GTAF 346
             GS ++     +P  P+           P    +   S    P PS    L    G+A 
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA- 833

Query: 347 TQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY--FSHPAIRYHPQETLKEFVQLVC 404
            Q   P    P       P        P++Q PGP   F  P      Q  L        
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 893

Query: 405 PDAGQQ--AGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVP-LPVPDTK--PP 459
           P    Q  A Q        S Q     P  P P+  P   PP   P+P LP P     PP
Sbjct: 894 PHTSLQLPASQSALQ----SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP 949

Query: 460 TTSTEG----GAASPTSPILVPGIKVAASHHPPDRPPDPFSTL 498
             S        A  P  P L P +   ++HHPP   P P   +
Sbjct: 950 HLSGPSPFSMNANLPPPPALKP-LSSLSTHHPPSAHPPPLQLM 991



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 65/276 (23%), Positives = 87/276 (31%), Gaps = 75/276 (27%)

Query: 291  EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 336
            +P   GQG  PG  S  +G     PG P P  L      G +    SP+          P
Sbjct: 843  QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901

Query: 337  SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-------------F 383
            +  S+L +      +P+   P A PH  P     PT+PI Q P P              F
Sbjct: 902  ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 957

Query: 384  S--------------------HPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLN----- 418
            S                    HP   + P   L    Q +     Q  G     N     
Sbjct: 958  SMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017

Query: 419  ----PNGSSQGKVHNPFLPTPMLP-------PPPPPPMARPVPLPVPDTKPPTT------ 461
                P G  Q     PF   P +P       PP  P  + P   P    +PP +      
Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 1077

Query: 462  -STEGGAASPTSPILVPGIKVAASHHPPDRPPDPFS 496
             S  GG++ P   + +    +  +  P   PP P S
Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRS 1113


>gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3
           [Homo sapiens]
          Length = 650

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 54/196 (27%), Positives = 68/196 (34%), Gaps = 39/196 (19%)

Query: 318 PSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPV------ITGPRASPHATP---STL 368
           P PT L   E +  +  S S T +L    T  H  +      ++ P +SP   P   S L
Sbjct: 273 PLPTPLDPEEPTFPALSSSSSTGNLAANLT--HLGIGGAGQGMSTPGSSPQHRPAGVSPL 330

Query: 369 HFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQV--GFLNPNGSSQGK 426
              T    QQ  P  S           L    Q V  DA     Q+   F    GS Q  
Sbjct: 331 SLSTEARRQQASPTLS----------PLSPITQAVAMDALSLEQQLPYAFFTQAGSQQ-- 378

Query: 427 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTS--------PILVPG 478
                 P P   PPPPPP A   P P P  + P     GG   P++        P L   
Sbjct: 379 ------PPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVT 432

Query: 479 IKVAASHHPPDRPPDP 494
           +  +    PP+ P  P
Sbjct: 433 VPSSLPQSPPENPGQP 448


>gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1
           [Homo sapiens]
          Length = 634

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 54/196 (27%), Positives = 68/196 (34%), Gaps = 39/196 (19%)

Query: 318 PSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPV------ITGPRASPHATP---STL 368
           P PT L   E +  +  S S T +L    T  H  +      ++ P +SP   P   S L
Sbjct: 257 PLPTPLDPEEPTFPALSSSSSTGNLAANLT--HLGIGGAGQGMSTPGSSPQHRPAGVSPL 314

Query: 369 HFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQV--GFLNPNGSSQGK 426
              T    QQ  P  S           L    Q V  DA     Q+   F    GS Q  
Sbjct: 315 SLSTEARRQQASPTLS----------PLSPITQAVAMDALSLEQQLPYAFFTQAGSQQ-- 362

Query: 427 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTS--------PILVPG 478
                 P P   PPPPPP A   P P P  + P     GG   P++        P L   
Sbjct: 363 ------PPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVT 416

Query: 479 IKVAASHHPPDRPPDP 494
           +  +    PP+ P  P
Sbjct: 417 VPSSLPQSPPENPGQP 432


>gi|124378039 SEC16 homolog A [Homo sapiens]
          Length = 2357

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 71/293 (24%), Positives = 105/293 (35%), Gaps = 68/293 (23%)

Query: 231  VSQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGE 290
            VS   +   +G N SLS + +SS  S+S       LPS+ + S+                
Sbjct: 870  VSSWALGGDSGENTSLSGIPTSSVLSLS-------LPSSVAQSN---------------- 906

Query: 291  EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL----KKSEKSGFSSP----SPSQTSSL 342
              F  G G S    +Q +      P  P P  L    +K  K+G + P    SP+ ++S+
Sbjct: 907  --FPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSV 964

Query: 343  GTAFTQHHRPVITGPRASPHA----TPSTLHFPTSPIIQQPGPYF---------SHPAIR 389
                  H   V  G +A+  +    T   L F  S  ++ P   +         S  ++ 
Sbjct: 965  VLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVA 1024

Query: 390  YHPQET------LKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPP 443
             HP+++      L  F Q V  DA  Q G             +     +P      PP  
Sbjct: 1025 SHPRQSGPGAPNLDRFYQQVTKDAQGQPGLE-----------RAQQELVPPQQQASPPQL 1073

Query: 444  PMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPDRPPDPFS 496
            P A    L  P++ P     +  A SP S +LV      A    P RPP   S
Sbjct: 1074 PKAMFSELSNPESLPAQGQAQNSAQSPASLVLVD-----AGQQLPPRPPQSSS 1121



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 53/227 (23%), Positives = 81/227 (35%), Gaps = 26/227 (11%)

Query: 263 RRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS-PGSGSQSSGWHEVEPGMPSPT 321
           R++L ST   SS+K    V   +  P    F    G   P + ++ S     EP +P P 
Sbjct: 59  RQALQSTPLGSSSKSSPPV---LQGPAPAGFSQHPGLLVPHTHARDSSQGPCEP-LPGPL 114

Query: 322 TLKKSEKSGFSS---------PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 372
           T  ++  S FS          P  ++++ +G +     + +   P   P   P T H   
Sbjct: 115 TQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSH-GG 173

Query: 373 SPIIQQPGPYFSHPAIRYHPQE-TLKEFVQLVCPDAG-QQAGQVGFLNPNGSSQGKVHNP 430
            P    PG     P  R +P +  +        P  G Q  GQ G +       G+  +P
Sbjct: 174 HPHGNMPG--LDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSP 231

Query: 431 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVP 477
                   P  P P   P    VP    P+   +G      SP++ P
Sbjct: 232 C-------PEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAP 271



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 15/98 (15%)

Query: 407  AGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPT----TS 462
            AG +A  V  LNP+G+ + +      P   + P  P P+   + +P PD + P     T 
Sbjct: 2187 AGTRARYVDVLNPSGTQRSEP--ALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTG 2244

Query: 463  TEGGAA---------SPTSPILVPGIKVAASHHPPDRP 491
             EG AA         +P   +L     +  S  P  RP
Sbjct: 2245 REGPAAARGLANPEPAPEPKVLSSAASLPGSELPSSRP 2282


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 57/238 (23%), Positives = 84/238 (35%), Gaps = 18/238 (7%)

Query: 257 MSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPG 316
           + P A  + L +  + +STK +  V  +   P   P      + P   +         P 
Sbjct: 773 LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPP 832

Query: 317 MPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPII 376
           +P P      ++S  + P PS  S + +   Q     I      P   P+    P  P+ 
Sbjct: 833 VPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ-----IASQFPPPPTPPAMESQPLKPVP 887

Query: 377 QQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPM 436
               P  S PA++  P+      + +  PD      +   + P          P  P P 
Sbjct: 888 ANVAPQ-SPPAVKAKPKWQPSS-IPVPSPDFPPPPPESSLVFPPP--------PPSPVPA 937

Query: 437 LPPPPPP-PMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVA--ASHHPPDRP 491
            PPPPPP     P     P  K   TS+ GG   P +P     IK +  A H  P RP
Sbjct: 938 PPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRP 995



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 11/87 (12%)

Query: 417 LNPNGSSQGKVHNPFL---PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 473
           L P  S Q K+  P+    P+P LPPPPPP    P P P P   PP  S    +A   +P
Sbjct: 605 LVPPLSPQPKIVTPYTASQPSPPLPPPPPP--PPPPPPPPPPPPPPLPSQSAPSAGSAAP 662

Query: 474 ILVPGIKVA----ASHHPPD--RPPDP 494
           + V    +     AS H     +PP P
Sbjct: 663 MFVKYSTITRLQNASQHSGALFKPPTP 689



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/87 (35%), Positives = 37/87 (42%), Gaps = 20/87 (22%)

Query: 426 KVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPP--------TTSTE------GGAASPT 471
           K+H     T + PP PPPP   P+P P+P   PP         TST+        AA PT
Sbjct: 748 KIHQVQHITQVAPPTPPPP--PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805

Query: 472 SPILVPGIK----VAASHHPPDRPPDP 494
               VP  K      AS+ PP  P  P
Sbjct: 806 PTPPVPPAKKQPAFPASYIPPSPPTPP 832



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 33/117 (28%), Positives = 40/117 (34%), Gaps = 34/117 (29%)

Query: 413 QVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTST--------- 463
           Q   + P  +SQ     P  P P  PPPPPPP   P P P+P    P+  +         
Sbjct: 612 QPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP---PPPPPLPSQSAPSAGSAAPMFVKYS 668

Query: 464 -----------EGGAASPTSP-----------ILVPGIKVAASHHPPDRPPDPFSTL 498
                       G    P +P           ILVP   V     PP  PP P S +
Sbjct: 669 TITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAM 725



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 11/74 (14%)

Query: 430 PFLPTPMLPPP-----------PPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPG 478
           P  PTP +PP            PP P   PVP+P P      +       SP SP+    
Sbjct: 803 PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVV 862

Query: 479 IKVAASHHPPDRPP 492
            ++A+   PP  PP
Sbjct: 863 KQIASQFPPPPTPP 876



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 61/265 (23%), Positives = 90/265 (33%), Gaps = 34/265 (12%)

Query: 245 SLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSG 304
           S  D  S S  S+  G+   S+P + S  S +    V D       +P    + +S  S 
Sbjct: 522 SAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDT------QPAGHVRSQSIVSS 575

Query: 305 SQSSGWHEVEPGMPSPTTLKKSEKSGFSS--PSPSQTSSLGTAFTQHH-RPVITGPRASP 361
             S  W        S     +S    ++S  P  S    + T +T     P +  P   P
Sbjct: 576 VFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP 635

Query: 362 HATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNG 421
              P     P  P+  Q  P     A  +    T+         +A Q +G + F  P  
Sbjct: 636 PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRL-----QNASQHSGAL-FKPPTP 689

Query: 422 ---SSQGKVHNPFLPT-----PMLPPPPPP----PMARPVPLPVPDTKPPTTSTEGGAAS 469
               SQ       +P      P  PPPPPP     MA+  P P   + P         ++
Sbjct: 690 PVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQ-------FSA 742

Query: 470 PTSPILVPGIKVAASHHPPDRPPDP 494
           P  P+ +  ++      PP  PP P
Sbjct: 743 PPPPLKIHQVQHITQVAPPTPPPPP 767



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 47/175 (26%), Positives = 61/175 (34%), Gaps = 26/175 (14%)

Query: 315  PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTS- 373
            P  P PT     +KSG      S+TSS G       +P  T  R S   + S    P   
Sbjct: 939  PPPPPPTASPTPDKSGSPGKKTSKTSSPGGK-----KPPPTPQRNSSIKSSSGAEHPEPK 993

Query: 374  -PIIQQPGPYFSHPAIRYHP-QETLKEFVQLVCPDAGQ------------QAGQVGFLNP 419
             P +      F+ PA    P +ETL        P  G+            Q G V    P
Sbjct: 994  RPSVDSLVSKFTPPAESGSPSKETLPP--PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051

Query: 420  NGSSQGKVHNPFLPTPM----LPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASP 470
              S +GK      P+P      PPPPP       P+ +P      TS +    +P
Sbjct: 1052 VLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNP 1106


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 62/257 (24%), Positives = 95/257 (36%), Gaps = 27/257 (10%)

Query: 250 ESSSYYSMSPGAMRRS---LPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 306
           E+    ++S GA R +    P T S +  +R ++   E+  P   P    +  + G    
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208

Query: 307 SSGWHEVEPGMPSPTTLKK-SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATP 365
            S   E     PSP   ++ S   G   P+    SS  T  +    P  +GP A    TP
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS---PARSGPSA--RGTP 263

Query: 366 STLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQ-QAGQVGFLNPNGSSQ 424
                P+ P  +  G     P     P++          P  G   +  +   +P+G+  
Sbjct: 264 RAPAHPSQP--KPKGLQALRPPQVTPPRKD-------AAPALGPLSSSPLATPSPSGTKA 314

Query: 425 GKVHNPFLPTPMLPP--PPPPPMARPVPLPVPD-TKPPTTSTEGGAASPTSPILVPGIKV 481
             V  P      LP   PP PP+A P+PL  P  + PP+  T      P+ P   P    
Sbjct: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT-----LPSPPATPPSQAP 369

Query: 482 AASHHPPDRPPDPFSTL 498
            +   PP + P    T+
Sbjct: 370 PSMTTPPMQAPPSLQTI 386



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 51/194 (26%), Positives = 73/194 (37%), Gaps = 27/194 (13%)

Query: 311 HEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHF 370
           H   P  P+P  L+ +  S  ++P P   SS+ T   Q   P +  P      +P     
Sbjct: 557 HLETPPCPAPCPLQ-APPSPLTTPPPETPSSIATPPPQAP-PALASPPLQGLPSPPLSPL 614

Query: 371 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 430
            T P   Q  P  + P ++  P            P A      +   +P   +   VH  
Sbjct: 615 ATPP--PQAPPXLALPPLQAPPS-----------PPASPPLSPLATPSPQAPNALAVH-- 659

Query: 431 FLPTPMLPPPPPP---PMARPVPLPV-PDTKPPTTSTEGGAAS----PTSPILVPGIKVA 482
            L  P  PPP PP   P + P   PV P   PP+ +    AA     P SP   P +  +
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719

Query: 483 ASHHPPDRPPDPFS 496
           A+  PP + P P +
Sbjct: 720 AT--PPPQAPPPLA 731



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 47/178 (26%), Positives = 64/178 (35%), Gaps = 26/178 (14%)

Query: 331 FSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQ---QPGPYFSHPA 387
           F + SP QT +   + T   RP  T P + P   P +L  P SP +Q    P        
Sbjct: 429 FLTMSPRQTQA---SLTSPSRPASTPPDSPPLQAPLSL--PASPPLQTSLSPAVSPLSSP 483

Query: 388 IRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTP---MLPPP---- 440
           +  HP + L             QA     + P   +Q  +  P L TP   +  PP    
Sbjct: 484 LTIHPLQALSSLAS-----HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538

Query: 441 ----PPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAAS--HHPPDRPP 492
               PPP      PL  P  + P         +P SP+  P  +  +S    PP  PP
Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP 596



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 49/184 (26%), Positives = 64/184 (34%), Gaps = 22/184 (11%)

Query: 316 GMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS-------TL 368
           G+PSP        S  ++P P     L     Q        P  SP ATPS        +
Sbjct: 605 GLPSPPL------SPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 658

Query: 369 HFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH 428
           H   +P    P P    P   + P  +         P     +     L    S      
Sbjct: 659 HLLQAPFSPPPSPPVQAP---FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP- 714

Query: 429 NPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPP 488
            P  P+   PP  PPP+A P PL VP + PP +     +A+P  P  VP +  A     P
Sbjct: 715 -PMSPSATPPPQAPPPLAAP-PLQVPPS-PPASPPMSPSATP--PPRVPPLLAAPPLQVP 769

Query: 489 DRPP 492
             PP
Sbjct: 770 PSPP 773



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 57/225 (25%), Positives = 84/225 (37%), Gaps = 27/225 (12%)

Query: 287 SPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAF 346
           SP   P  T   ++P S +      +V P  P+   +  S      +P P     L    
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739

Query: 347 TQHHRPVITG-----PRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQ 401
           +    P ++      PR  P      L  P SP    P    + P  +  P         
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799

Query: 402 LVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLP-TPMLPPPP--PPPMARPVPLPVPDTKP 458
           L  P A    GQ  F +P+ S         LP +P+  PPP  PP +A P+ L VP + P
Sbjct: 800 LPSPPASFP-GQAPF-SPSAS---------LPMSPLATPPPQAPPVLAAPL-LQVPPSPP 847

Query: 459 PTTSTEGGAASPT----SPILVPGIKVAASHHPPDRPP-DPFSTL 498
            + + +     PT    + +  P + +A +  PP  P   P STL
Sbjct: 848 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 892


>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
          Length = 1488

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 44/143 (30%), Positives = 57/143 (39%), Gaps = 20/143 (13%)

Query: 357  PRASPHATPSTLHFPTSPI-IQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVG 415
            P+ +PH     LH PTSP+ +  P P    PA +  P+  +      + P AG   G   
Sbjct: 1351 PQFAPHGR-HPLHQPTSPLPLYSPAPQHP-PAHKQGPKHFIFSHHPQMMPAAGAAGGPGS 1408

Query: 416  FLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTK----PPTTSTEGGAASPT 471
               P G S    H+P  P     P PP P   P+P P P T     PPT        SP 
Sbjct: 1409 --RPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPT--------SPH 1458

Query: 472  SPILV---PGIKVAASHHPPDRP 491
             P+     PG     S +P  +P
Sbjct: 1459 GPLHASGPPGTANPPSANPKAKP 1481



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 24/87 (27%), Positives = 31/87 (35%), Gaps = 3/87 (3%)

Query: 408  GQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGA 467
            G   G +G L    S    +H  +   P   PPP  P  +P  LP P  +PP     G  
Sbjct: 1248 GHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQP-SLPPPPQQPPPLPQLG-- 1304

Query: 468  ASPTSPILVPGIKVAASHHPPDRPPDP 494
            + P  P   P +      H     P P
Sbjct: 1305 SIPPPPASAPPVGPHRHFHAHGPVPGP 1331



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 13/39 (33%), Positives = 22/39 (56%)

Query: 406  DAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPP 444
            DAG++  +    + + + +G V +   P   +PPPPPPP
Sbjct: 1149 DAGKRGRRNSVGSLDSTIEGSVISSPRPHQRMPPPPPPP 1187


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 72/317 (22%), Positives = 98/317 (30%), Gaps = 85/317 (26%)

Query: 184 HAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPN 243
           H A   + + P  P  A  K + +  +L                +  + + P+ A  G  
Sbjct: 287 HIASDCKFQRPGDPQSAQDKARMDKEYLSL--------------MAELGEAPVPASVGST 332

Query: 244 FSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGS 303
              +    +S  +  P A   + P  S  S+T+               P +   G  P  
Sbjct: 333 SGPATTPLAS--APRPAAPANNPPPPSLMSTTQ-------------SRPPWMNSG--PSE 375

Query: 304 GSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHA 363
                G H   PG P            F  P PS T   G    QH+      P   P  
Sbjct: 376 SRPYHGMHGGGPGGPG------GGPHSFPHPLPSLTGGHGGHPMQHN------PNGPP-- 421

Query: 364 TPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSS 423
            P  +  P  P+ Q P     HP   + P            P   Q  G      P GS 
Sbjct: 422 -PPWMQPPPPPMNQGP-----HPPGHHGP------------PPMDQYLGST----PVGSG 459

Query: 424 -----QGKVHNPFLPTPMLPPPPPPPMARPVPLP-------------VPDTKPPTTSTEG 465
                QGK   P  P  M+PPPPPPP  +P P P              P   PP++S   
Sbjct: 460 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMAS 519

Query: 466 GAASPTSPILVPGIKVA 482
               P     +P   +A
Sbjct: 520 STPLPWQQRSLPAAAMA 536


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,481,667
Number of Sequences: 37866
Number of extensions: 1589128
Number of successful extensions: 24035
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 461
Number of HSP's successfully gapped in prelim test: 879
Number of HSP's that attempted gapping in prelim test: 11241
Number of HSP's gapped (non-prelim): 7120
length of query: 498
length of database: 18,247,518
effective HSP length: 106
effective length of query: 392
effective length of database: 14,233,722
effective search space: 5579619024
effective search space used: 5579619024
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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