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Search of human proteins with 30795212
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
(579 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 1142 0.0
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 843 0.0
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 749 0.0
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 719 0.0
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 459 e-129
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 80 4e-15
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 76 7e-14
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 75 2e-13
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 75 2e-13
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 75 2e-13
gi|17402900 far upstream element-binding protein [Homo sapiens] 74 4e-13
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 73 8e-13
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 72 1e-12
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 71 3e-12
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 71 3e-12
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 70 4e-12
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 70 4e-12
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 70 4e-12
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 70 4e-12
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 70 4e-12
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 67 6e-11
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 66 8e-11
gi|4885409 high density lipoprotein binding protein [Homo sapiens] 63 8e-10
gi|42716280 high density lipoprotein binding protein [Homo sapiens] 63 8e-10
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 62 2e-09
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 61 2e-09
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 61 2e-09
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 61 2e-09
gi|13899354 RNA binding motif protein 4B [Homo sapiens] 57 6e-08
gi|93277122 RNA binding motif protein 4 [Homo sapiens] 56 8e-08
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 1142 bits (2955), Expect = 0.0
Identities = 579/579 (100%), Positives = 579/579 (100%)
Query: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK
Sbjct: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
Query: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA
Sbjct: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
Query: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS 180
VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS
Sbjct: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS 180
Query: 181 RQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA 240
RQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA
Sbjct: 181 RQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA 240
Query: 241 EKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLK 300
EKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLK
Sbjct: 241 EKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLK 300
Query: 301 KIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNL 360
KIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNL
Sbjct: 301 KIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNL 360
Query: 361 QAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAI 420
QAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAI
Sbjct: 361 QAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAI 420
Query: 421 IGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFV 480
IGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFV
Sbjct: 421 IGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFV 480
Query: 481 SPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKIT 540
SPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKIT
Sbjct: 481 SPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKIT 540
Query: 541 GHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK 579
GHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
Sbjct: 541 GHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK 579
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 843 bits (2179), Expect = 0.0
Identities = 433/585 (74%), Positives = 496/585 (84%), Gaps = 14/585 (2%)
Query: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
MNKLYIGNL+E+ P+DLE +F + KI SG FLVK+GYAFVDCPDE WA+KAIE SGK
Sbjct: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
Query: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
+EL GK +E+EHSVPK+QR RK+QIRNIPP L+WEVLDSLL QYG VE+CEQVNT+SETA
Sbjct: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
Query: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS 180
VVNVTYS+++Q RQA+ KLNG QLEN LKV+YIPDE A Q P RG G G RG
Sbjct: 121 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIA-QGPENGRRG--GFGSRGQP 177
Query: 181 RQGSP---GSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENA 237
RQGSP G+ +KQ+ D+PLRLLVPTQ+VGAIIGKEGATIRNITKQTQSKIDVHRKENA
Sbjct: 178 RQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENA 237
Query: 238 GAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGR 297
GAAEK+I++ STPEG S+ACK ILEIMHKEA+D K +E+PLKILAHNNFVGRLIGKEGR
Sbjct: 238 GAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGR 297
Query: 298 NLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIAS 357
NLKK+EQDT+TKITIS LQ+LTLYNPERTITVKG +E C +AE+EIMKK+RE+YEND+A+
Sbjct: 298 NLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAA 357
Query: 358 MNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMT--PPYPQFEQS-ETETVHLFIPA 414
M+LQ+HLIPGLNL A+GLFP +S PP PPS++T PY F Q+ E E V +FIPA
Sbjct: 358 MSLQSHLIPGLNLAAVGLFPASSSAVPP---PPSSVTGAAPYSSFMQAPEQEMVQVFIPA 414
Query: 415 LSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKI 474
+VGAIIGK+GQHIKQLSRFA ASIKIAP E PD+KVRMVIITGPPEAQFKAQGRIYGK+
Sbjct: 415 QAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKL 474
Query: 475 KEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQ 534
KEENF PKEEVKLE HIRVP+ AAGRVIGKGGKTVNELQNL++AEVVVPRDQTPDENDQ
Sbjct: 475 KEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQ 534
Query: 535 VVVKITGHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK 579
V+VKI GHFYA Q+AQRKI++IL QVKQ Q+ QS Q+RRK
Sbjct: 535 VIVKIIGHFYASQMAQRKIRDILAQVKQQHQKG--QSNQAQARRK 577
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 749 bits (1934), Expect = 0.0
Identities = 386/591 (65%), Positives = 466/591 (78%), Gaps = 29/591 (4%)
Query: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
MNKLYIGNLS DL +F D K+P++G L+K+GYAFVD PD++WA++AIE LSGK
Sbjct: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
Query: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
+ELHGK +EV++SV K+ R RK+QIRNIPPHLQWEVLD LL QYG VE+ EQVNTD+ETA
Sbjct: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
Query: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS 180
VVNVTY+++++A+ A++KL+G Q EN++ K++YIPDE + +P Q R G S
Sbjct: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQ----RAQRGDHSSR 177
Query: 181 RQG-SPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGA 239
QG +PG S+ + D PLR+LVPTQFVGAIIGKEG TI+NITKQTQS++D+HRKEN+GA
Sbjct: 178 EQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGA 237
Query: 240 AEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNL 299
AEK +TI +TPEGTS AC+ ILEIM KEA + K EEIPLKILAHN VGRLIGKEGRNL
Sbjct: 238 AEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNL 297
Query: 300 KKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMN 359
KKIE +T TKITIS LQ+L++YNPERTITVKG VE CA AE EIMKK+RE++END+ ++N
Sbjct: 298 KKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357
Query: 360 LQAHLIPGLNLNALGLF--------PPTS--GMPPPT--------SGPPSAMTP-----P 396
QA+LIPGLNL+ALG+F PP G PP SG S++ P P
Sbjct: 358 QQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGP 417
Query: 397 YPQFEQ-SETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVI 455
+P E E V+LFIP +VGAIIGK+G HIKQL+RFAGASIKIAPAE PD RMVI
Sbjct: 418 FPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVI 477
Query: 456 ITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQN 515
ITGPPEAQFKAQGRI+GK+KEENF +PKEEVKLEAHIRVPS AGRVIGKGGKTVNELQN
Sbjct: 478 ITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQN 537
Query: 516 LSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQ 566
L+SAEV+VPRDQTPDEN++V+V+I GHF+A Q AQRKI+EI+ QVKQ +Q+
Sbjct: 538 LTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQK 588
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 719 bits (1856), Expect = 0.0
Identities = 369/567 (65%), Positives = 445/567 (78%), Gaps = 24/567 (4%)
Query: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
MNKLYIGNLS DL +F D K+P++G L+K+GYAFVD PD++WA++AIE LSGK
Sbjct: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
Query: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
+ELHGK +EV++SV K+ R RK+QIRNIPPHLQWEVLD LL QYG VE+ EQVNTD+ETA
Sbjct: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
Query: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS 180
VVNVTY+++++A+ A++KL+G Q EN++ K++YIPDE + +P Q R G S
Sbjct: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQ----RAQRGDHSSR 177
Query: 181 RQG-SPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGA 239
QG +PG S+ + D PLR+LVPTQFVGAIIGKEG TI+NITKQTQS++D+HRKEN+GA
Sbjct: 178 EQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGA 237
Query: 240 AEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNL 299
AEK +TI +TPEGTS AC+ ILEIM KEA + K EEIPLKILAHN VGRLIGKEGRNL
Sbjct: 238 AEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNL 297
Query: 300 KKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMN 359
KKIE +T TKITIS LQ+L++YNPERTITVKG VE CA AE EIMKK+RE++END+ ++N
Sbjct: 298 KKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357
Query: 360 LQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGA 419
+ G F S + P P YP E E V+LFIP +VGA
Sbjct: 358 THS-----------GYF---SSLYPHHQFGPFPHHHSYP-----EQEIVNLFIPTQAVGA 398
Query: 420 IIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENF 479
IIGK+G HIKQL+RFAGASIKIAPAE PD RMVIITGPPEAQFKAQGRI+GK+KEENF
Sbjct: 399 IIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENF 458
Query: 480 VSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKI 539
+PKEEVKLEAHIRVPS AGRVIGKGGKTVNELQNL+SAEV+VPRDQTPDEN++V+V+I
Sbjct: 459 FNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRI 518
Query: 540 TGHFYACQVAQRKIQEILTQVKQHQQQ 566
GHF+A Q AQRKI+EI+ QVKQ +Q+
Sbjct: 519 IGHFFASQTAQRKIREIVQQVKQQEQK 545
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 459 bits (1181), Expect = e-129
Identities = 234/324 (72%), Positives = 274/324 (84%), Gaps = 8/324 (2%)
Query: 259 SILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQEL 318
+++ + + + + +E+PLKILAHNNFVGRLIGKEGRNLKK+EQDT+TKITIS LQ+L
Sbjct: 120 AVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDL 179
Query: 319 TLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPP 378
TLYNPERTITVKG +E C +AE+EIMKK+RE+YEND+A+M+LQ+HLIPGLNL A+GLFP
Sbjct: 180 TLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPA 239
Query: 379 TSGMPPPTSGPPSAMT--PPYPQFEQS-ETETVHLFIPALSVGAIIGKQGQHIKQLSRFA 435
+S PP PPS++T PY F Q+ E E V +FIPA +VGAIIGK+GQHIKQLSRFA
Sbjct: 240 SSSAVPP---PPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFA 296
Query: 436 GASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVP 495
ASIKIAP E PD+KVRMVIITGPPEAQFKAQGRIYGK+KEENF PKEEVKLE HIRVP
Sbjct: 297 SASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVP 356
Query: 496 SFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQE 555
+ AAGRVIGKGGKTVNELQNL++AEVVVPRDQTPDENDQV+VKI GHFYA Q+AQRKI++
Sbjct: 357 ASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRD 416
Query: 556 ILTQVKQHQQQKALQSGPPQSRRK 579
IL QVKQ Q+ QS Q+RRK
Sbjct: 417 ILAQVKQQHQKG--QSNQAQARRK 438
Score = 229 bits (583), Expect = 7e-60
Identities = 157/485 (32%), Positives = 238/485 (49%), Gaps = 86/485 (17%)
Query: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
MNKLYIGNL+E+ P+DLE +F + KI SG FLVK+GYAFVDCPDE WA+KAIE SGK
Sbjct: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
Query: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
+EL GK +E+EHSVPK+QR RK+QIRNIPP L+WEVLDSLL QYG VE+CEQVNT+SETA
Sbjct: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
Query: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS 180
VVNVTYS+++Q RQA + +P ++ A N + + G+ G +
Sbjct: 121 VVNVTYSNREQTRQADE----------------VPLKILAHNNFVGRLIGKEGRNLK-KV 163
Query: 181 RQGSPGSVSKQKPCDL----PLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN 236
Q + ++ DL P R + + E ++ + + ++ + ++
Sbjct: 164 EQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQS 223
Query: 237 ----------AGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNN 286
G S + + P + M Q++ +++
Sbjct: 224 HLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEM-------VQVFIPAQ 276
Query: 287 FVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKK 346
VG +IGK+G+++K++ + I I+P + T + R + + G E KA+ I K
Sbjct: 277 AVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPDSKVRMVIITGPPEAQFKAQGRIYGK 334
Query: 347 IRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETE 406
++E F P E+ + E
Sbjct: 335 LKEE-----------------------NFFGPK---------------------EEVKLE 350
Query: 407 TVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVI-ITGPPEAQFK 465
T H+ +PA + G +IGK G+ + +L A + + + PD ++++ I G A
Sbjct: 351 T-HIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQM 409
Query: 466 AQGRI 470
AQ +I
Sbjct: 410 AQRKI 414
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 80.5 bits (197), Expect = 4e-15
Identities = 75/302 (24%), Positives = 139/302 (46%), Gaps = 29/302 (9%)
Query: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
L +RLL+ + VG+IIGK+G T++ + +++ ++I++ + G + I ++ P T A
Sbjct: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI----SEGNCPERIVTITGP--TDA 99
Query: 256 ACKSILEIMHKEAQDI---------KFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
K+ I +K +DI + L+++ + G LIGK G +K+I + T
Sbjct: 100 IFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIREST 159
Query: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESY---------ENDIAS 357
++ ++ ++ + ER +T+ G + + ++I + E+Y D+
Sbjct: 160 GAQVQVAG--DMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTK 217
Query: 358 MN-LQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVH-LFIPAL 415
++ L P L P +P +S + + S + H L IP
Sbjct: 218 LHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPND 277
Query: 416 SVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIK 475
+G IIG+QG I ++ + +GA IKIA A ++ R + ITG P AQ I ++
Sbjct: 278 LIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSE-RQITITGTPANISLAQYLINARLT 336
Query: 476 EE 477
E
Sbjct: 337 SE 338
Score = 73.9 bits (180), Expect = 4e-13
Identities = 45/137 (32%), Positives = 73/137 (53%), Gaps = 8/137 (5%)
Query: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R+V ITGP +A F
Sbjct: 45 TLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIF 101
Query: 465 KAQGRIYGKIKEENFVS-----PKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
KA I K +E+ S + + + VP+ G +IGKGG + E++ + A
Sbjct: 102 KAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGA 161
Query: 520 EVVVPRDQTPDENDQVV 536
+V V D P+ ++ V
Sbjct: 162 QVQVAGDMLPNSTERAV 178
Score = 72.8 bits (177), Expect = 8e-13
Identities = 74/338 (21%), Positives = 125/338 (36%), Gaps = 103/338 (30%)
Query: 277 IPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETC 336
+ +++L H VG +IGK+G +KK+ +++ +I IS PER +T+ G +
Sbjct: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN-----CPERIVTITGPTDAI 100
Query: 337 AKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPP 396
KA I K E N +++ P TS PP
Sbjct: 101 FKAFAMIAYKFEEDIINSMSNS-------------------------PATSKPPV----- 130
Query: 397 YPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVII 456
T+ L +PA G++IGK G IK++ GA +++A P++ R V I
Sbjct: 131 ----------TLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
Query: 457 TGPPEA---------------------------------QFKAQGRIYGKIKEENFVSPK 483
+G P+A Q Q + + + N P
Sbjct: 181 SGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPG 240
Query: 484 EEVKLEA-----------------------HIRVPSFAAGRVIGKGGKTVNELQNLSSAE 520
E++ L + + +P+ G +IG+ G +NE++ +S A+
Sbjct: 241 EKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQ 300
Query: 521 VVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEILT 558
+ + Q+ ITG +AQ I LT
Sbjct: 301 IKIANATEGSSERQIT--ITGTPANISLAQYLINARLT 336
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 187 SVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITI 246
S + KP + LRL+VP G++IGK G+ I+ I + T +++ V + E+++TI
Sbjct: 122 SPATSKP-PVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
Query: 247 LSTPEGTSAACKSILEIMHKEAQDIKFTEEIP 278
TP+ K I +M EA I+ IP
Sbjct: 181 SGTPDAIIQCVKQICVVM-LEAYTIQGQYAIP 211
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 76.3 bits (186), Expect = 7e-14
Identities = 84/328 (25%), Positives = 142/328 (43%), Gaps = 55/328 (16%)
Query: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
L +RLL+ + VG+IIGK+G T++ + +++ ++I++ E+ +TI T A
Sbjct: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGNCPERIVTITGP---TDA 99
Query: 256 ACKSILEIMHKEAQDI---------KFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
K+ I +K +DI + L+++ + G LIGK G +K+I + T
Sbjct: 100 IFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIREST 159
Query: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES--------YENDIASM 358
++ ++ ++ + ER +T+ G + + ++I + ES Y AS
Sbjct: 160 GAQVQVA--GDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPAST 217
Query: 359 NL-----QAHLIPG----------LNLNALGL----FPPTSGMPPPTSG---PPSAMTPP 396
+ QA+ I G L+ L + FPP P G P +
Sbjct: 218 PVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEA 277
Query: 397 YPQFEQSE-------TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDA 449
QS T L IP +G IIG+QG I ++ + +GA IKIA A +
Sbjct: 278 QNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSS 337
Query: 450 KVRMVIITGPPEAQFKAQGRIYGKIKEE 477
+ R + ITG P AQ I ++ E
Sbjct: 338 E-RQITITGTPANISLAQYLINARLTSE 364
Score = 73.9 bits (180), Expect = 4e-13
Identities = 45/137 (32%), Positives = 73/137 (53%), Gaps = 8/137 (5%)
Query: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R+V ITGP +A F
Sbjct: 45 TLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIF 101
Query: 465 KAQGRIYGKIKEENFVS-----PKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
KA I K +E+ S + + + VP+ G +IGKGG + E++ + A
Sbjct: 102 KAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGA 161
Query: 520 EVVVPRDQTPDENDQVV 536
+V V D P+ ++ V
Sbjct: 162 QVQVAGDMLPNSTERAV 178
Score = 44.3 bits (103), Expect = 3e-04
Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 187 SVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITI 246
S + KP + LRL+VP G++IGK G+ I+ I + T +++ V + E+++TI
Sbjct: 122 SPATSKP-PVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
Query: 247 LSTPEGTSAACKSILEIM 264
TP+ K I +M
Sbjct: 181 SGTPDAIIQCVKQICVVM 198
Score = 39.3 bits (90), Expect = 0.010
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 9/93 (9%)
Query: 164 PLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITK 223
PL + L + S SP + + + L +P +G IIG++G I I +
Sbjct: 270 PLHSSEEAQNLMGQSSGLDASPPASTHE--------LTIPNDLIGCIIGRQGTKINEIRQ 321
Query: 224 QTQSKIDVHRKENAGAAEKSITILSTPEGTSAA 256
+ ++I + G++E+ ITI TP S A
Sbjct: 322 MSGAQIKI-ANATEGSSERQITITGTPANISLA 353
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/309 (24%), Positives = 139/309 (44%), Gaps = 33/309 (10%)
Query: 183 GSPGSVSKQKPCD--LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA 240
GS G + ++ L LR+L+ + VG+IIGK+G T++ I +Q+ ++I + + G+
Sbjct: 3 GSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI----SEGSC 58
Query: 241 EKSITILSTPEGTSAACKSILEIMHKEAQDI---------KFTEEIPLKILAHNNFVGRL 291
+ IT ++ T+A ++ I K +D+ + L+++ + G L
Sbjct: 59 PERITTIT--GSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSL 116
Query: 292 IGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES- 350
IGK G +K+I + T ++ ++ +L + ER +TV G + +I I ES
Sbjct: 117 IGKAGTKIKEIRETTGAQVQVA--GDLLPNSTERAVTVSGVPDAIILCVRQICAVILESP 174
Query: 351 -------YENDIASMNLQAHLIPGLNLNA-LGLFPP---TSGMPPPTSGPPSAMTPPYPQ 399
Y ++ + G ++ G P T + P A P
Sbjct: 175 PKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPG 234
Query: 400 FEQ-SETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITG 458
+ ++T + +P +G +IG+QG I ++ + +GA IKI +A A R V ITG
Sbjct: 235 LDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIG-NQAEGAGERHVTITG 293
Query: 459 PPEAQFKAQ 467
P + AQ
Sbjct: 294 SPVSIALAQ 302
Score = 63.9 bits (154), Expect = 4e-10
Identities = 61/227 (26%), Positives = 92/227 (40%), Gaps = 52/227 (22%)
Query: 277 IPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETC 336
+ L++L H VG +IGK+G +K+I + + +ITIS PER T+ G+
Sbjct: 18 LTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAV 72
Query: 337 AKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPP 396
A I K+ E L P G S PP
Sbjct: 73 FHAVSMIAFKLDED----------------------LCAAPANGGN---VSRPPV----- 102
Query: 397 YPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVII 456
T+ L IPA G++IGK G IK++ GA +++A P++ R V +
Sbjct: 103 ----------TLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTV 152
Query: 457 TGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVI 503
+G P+A +I I E SP + + H PS + G V+
Sbjct: 153 SGVPDAIILCVRQICAVILE----SPPKGATIPYH---PSLSLGTVL 192
Score = 62.4 bits (150), Expect = 1e-09
Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 8/141 (5%)
Query: 401 EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPP 460
E S T T+ + + VG+IIGK+G+ +K++ + A I I+ P+ R+ ITG
Sbjct: 13 ELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE---RITTITGST 69
Query: 461 EAQFKAQGRIYGKIKEENFVSPKE-----EVKLEAHIRVPSFAAGRVIGKGGKTVNELQN 515
A F A I K+ E+ +P + + +P+ G +IGK G + E++
Sbjct: 70 AAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRE 129
Query: 516 LSSAEVVVPRDQTPDENDQVV 536
+ A+V V D P+ ++ V
Sbjct: 130 TTGAQVQVAGDLLPNSTERAV 150
Score = 34.7 bits (78), Expect = 0.25
Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 472 GKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDE 531
G ++EE P+ + L + + G +IGK G+TV ++ SSA + + P+
Sbjct: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPER 61
Query: 532 NDQVVVKITGHFYACQVAQRKIQEIL 557
+ F+A + K+ E L
Sbjct: 62 ITTITGSTAAVFHAVSMIAFKLDEDL 87
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/309 (24%), Positives = 139/309 (44%), Gaps = 33/309 (10%)
Query: 183 GSPGSVSKQKPCD--LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA 240
GS G + ++ L LR+L+ + VG+IIGK+G T++ I +Q+ ++I + + G+
Sbjct: 3 GSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI----SEGSC 58
Query: 241 EKSITILSTPEGTSAACKSILEIMHKEAQDI---------KFTEEIPLKILAHNNFVGRL 291
+ IT ++ T+A ++ I K +D+ + L+++ + G L
Sbjct: 59 PERITTIT--GSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSL 116
Query: 292 IGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES- 350
IGK G +K+I + T ++ ++ +L + ER +TV G + +I I ES
Sbjct: 117 IGKAGTKIKEIRETTGAQVQVA--GDLLPNSTERAVTVSGVPDAIILCVRQICAVILESP 174
Query: 351 -------YENDIASMNLQAHLIPGLNLNA-LGLFPP---TSGMPPPTSGPPSAMTPPYPQ 399
Y ++ + G ++ G P T + P A P
Sbjct: 175 PKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPG 234
Query: 400 FEQ-SETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITG 458
+ ++T + +P +G +IG+QG I ++ + +GA IKI +A A R V ITG
Sbjct: 235 LDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIG-NQAEGAGERHVTITG 293
Query: 459 PPEAQFKAQ 467
P + AQ
Sbjct: 294 SPVSIALAQ 302
Score = 63.9 bits (154), Expect = 4e-10
Identities = 61/227 (26%), Positives = 92/227 (40%), Gaps = 52/227 (22%)
Query: 277 IPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETC 336
+ L++L H VG +IGK+G +K+I + + +ITIS PER T+ G+
Sbjct: 18 LTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAV 72
Query: 337 AKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPP 396
A I K+ E L P G S PP
Sbjct: 73 FHAVSMIAFKLDED----------------------LCAAPANGGN---VSRPPV----- 102
Query: 397 YPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVII 456
T+ L IPA G++IGK G IK++ GA +++A P++ R V +
Sbjct: 103 ----------TLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTV 152
Query: 457 TGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVI 503
+G P+A +I I E SP + + H PS + G V+
Sbjct: 153 SGVPDAIILCVRQICAVILE----SPPKGATIPYH---PSLSLGTVL 192
Score = 62.4 bits (150), Expect = 1e-09
Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 8/141 (5%)
Query: 401 EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPP 460
E S T T+ + + VG+IIGK+G+ +K++ + A I I+ P+ R+ ITG
Sbjct: 13 ELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE---RITTITGST 69
Query: 461 EAQFKAQGRIYGKIKEENFVSPKE-----EVKLEAHIRVPSFAAGRVIGKGGKTVNELQN 515
A F A I K+ E+ +P + + +P+ G +IGK G + E++
Sbjct: 70 AAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRE 129
Query: 516 LSSAEVVVPRDQTPDENDQVV 536
+ A+V V D P+ ++ V
Sbjct: 130 TTGAQVQVAGDLLPNSTERAV 150
Score = 34.7 bits (78), Expect = 0.25
Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 472 GKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDE 531
G ++EE P+ + L + + G +IGK G+TV ++ SSA + + P+
Sbjct: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPER 61
Query: 532 NDQVVVKITGHFYACQVAQRKIQEIL 557
+ F+A + K+ E L
Sbjct: 62 ITTITGSTAAVFHAVSMIAFKLDEDL 87
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 74.7 bits (182), Expect = 2e-13
Identities = 88/382 (23%), Positives = 159/382 (41%), Gaps = 70/382 (18%)
Query: 202 VPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSIL 261
VP + VG IIG+ G I I ++ KI + E++G E+ + TPE A + +
Sbjct: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQI-ASESSGIPERPCVLTGTPESIEQAKRLLG 142
Query: 262 EIMHKEAQDIKFTEEIPL-----KILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQ 316
+I+ + F +I +IL + VG +IG+ G +K++++ T K+ + +Q
Sbjct: 143 QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVM--IQ 200
Query: 317 ELTL-YNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGL 375
+ L ++ + + G+ +A E +++ IRE + D + G
Sbjct: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVR--------------GD 246
Query: 376 FPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFA 435
F G ++ + +P +VG +IG+ G+ IK++ A
Sbjct: 247 FNSRMG-----------------------GGSIEVSVPRFAVGIVIGRNGEMIKKIQNDA 283
Query: 436 GASIKIAPAEAPDAKVRMVIITGPPE---------------AQFK------AQGRIYGKI 474
G I+ P + + R + GPP+ AQ + A R G+
Sbjct: 284 GVRIQFKPDDGISPE-RAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRG 342
Query: 475 KEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQ 534
+ + V V+ E VP+ G VIGKGG+ + + S A V + R+ P+ +
Sbjct: 343 RGDWSVGAPGGVQ-EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPN 401
Query: 535 V-VVKITGHFYACQVAQRKIQE 555
+ I G +VA++ I E
Sbjct: 402 LRRFTIRGVPQQIEVARQLIDE 423
Score = 65.1 bits (157), Expect = 2e-10
Identities = 44/156 (28%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Query: 412 IPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIY 471
+P VG IIG+ G+ I ++ +G I+IA +E+ R ++TG PE+ +A+ R+
Sbjct: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIA-SESSGIPERPCVLTGTPESIEQAK-RLL 141
Query: 472 GKIKEENFVSPKEEVKLEAH-----IRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRD 526
G+I + P ++++ I +P+ G VIG+GG+T+ +LQ + ++V+ +D
Sbjct: 142 GQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQD 201
Query: 527 QTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQ 562
++ITG + Q A+ + EI+ + Q
Sbjct: 202 GPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQ 237
Score = 65.1 bits (157), Expect = 2e-10
Identities = 81/326 (24%), Positives = 133/326 (40%), Gaps = 40/326 (12%)
Query: 169 RGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSK 228
+ +R LGQ + PG + +L+P VG +IG+ G TI+ + ++T K
Sbjct: 136 QAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVK 195
Query: 229 -IDVHRKENAGAAEKSITILSTPEGTSAACKSILEIM-HKEAQDIK-----FTEEI---P 278
+ + A+K + I A + +LEI+ K+ D + F +
Sbjct: 196 MVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGS 255
Query: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338
+++ VG +IG+ G +KKI+ D +I P + +PER V G + C
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGI---SPERAAQVMGPPDRCQH 312
Query: 339 AEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYP 398
A I + I + E D L A G G + G P +
Sbjct: 313 AAHIISELILTAQERD-GFGGLAAARGRG------------RGRGDWSVGAPGGV----- 354
Query: 399 QFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIA--PAEAPDAKVRMVII 456
Q T TV PA G +IGK G++IK +++ +GA +++ P D +R I
Sbjct: 355 ---QEITYTV----PADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTI 407
Query: 457 TGPPEAQFKAQGRIYGKIKEENFVSP 482
G P+ A+ I K+ N +P
Sbjct: 408 RGVPQQIEVARQLIDEKVGGTNLGAP 433
Score = 49.7 bits (117), Expect = 7e-06
Identities = 66/296 (22%), Positives = 113/296 (38%), Gaps = 73/296 (24%)
Query: 285 NNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEE--- 341
+ VG +IG+ G + +I+ ++ KI I+ PER + G E+ +A+
Sbjct: 86 DKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI---PERPCVLTGTPESIEQAKRLLG 142
Query: 342 EIMKKIRES--YENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQ 399
+I+ + R + NDI
Sbjct: 143 QIVDRCRNGPGFHNDI-------------------------------------------- 158
Query: 400 FEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGAS-IKIAPAEAPDAKVRMVIITG 458
S + + IPA VG +IG+ G+ IKQL G + I P + + ITG
Sbjct: 159 --DSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITG 216
Query: 459 PPEAQFKAQGRIYGKIKEE----------NFVSPKEEVKLEAHIRVPSFAAGRVIGKGGK 508
+A+ + I+E+ +F S +E + VP FA G VIG+ G+
Sbjct: 217 DAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIE--VSVPRFAVGIVIGRNGE 274
Query: 509 TVNELQNLSSAEVVVPRDQ--TPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQ 562
+ ++QN + + D +P+ QV+ G CQ A I E++ ++
Sbjct: 275 MIKKIQNDAGVRIQFKPDDGISPERAAQVM----GPPDRCQHAAHIISELILTAQE 326
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 73.9 bits (180), Expect = 4e-13
Identities = 95/430 (22%), Positives = 173/430 (40%), Gaps = 82/430 (19%)
Query: 161 QQNPLQ---QPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGAT 217
Q+ PL+ QP ++ Q S P +Q + VP VG IIG+ G
Sbjct: 63 QKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQ 122
Query: 218 IRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTE-- 275
I I +++ KI + ++ G E+S + TPE +A + + +I+ K F
Sbjct: 123 ISRIQQESGCKIQI-APDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGD 181
Query: 276 ---EIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERT-----I 327
+I+ + G +IGK G +K++++ K+ + +Q+ P+ T +
Sbjct: 182 GPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVM--IQD----GPQNTGADKPL 235
Query: 328 TVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTS 387
+ G+ +A+E +++ IR+ G F
Sbjct: 236 RITGDPYKVQQAKEMVLELIRDQ-----------------------GGFREVRNEYGSRI 272
Query: 388 GPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAP 447
G + P P+F +VG +IG+ G+ IK++ AG I+ P +
Sbjct: 273 GGNEGIDVPIPRF---------------AVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGT 317
Query: 448 DAKVRMVIITGPPE-AQFKAQ--------------------GRIYGKIKEENFVSPKEEV 486
+ R+ ITGPP+ Q A+ GR G+ + + P +
Sbjct: 318 TPE-RIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGL 376
Query: 487 KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQV-VVKITGHFYA 545
+ E + VP+ G +IGKGG+T+ + S A + + R+ P+ + + + I G
Sbjct: 377 Q-EFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQ 435
Query: 546 CQVAQRKIQE 555
A++ I+E
Sbjct: 436 IDYARQLIEE 445
Score = 71.6 bits (174), Expect = 2e-12
Identities = 76/316 (24%), Positives = 126/316 (39%), Gaps = 41/316 (12%)
Query: 171 RRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKID 230
+R L Q + +PG P + +++P G +IGK G TI+ + ++ K+
Sbjct: 161 KRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMV 220
Query: 231 VHRK--ENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNF- 287
+ + +N GA +K + I P A + +LE++ + + E +I +
Sbjct: 221 MIQDGPQNTGA-DKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGID 279
Query: 288 -------VGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAE 340
VG +IG+ G +KKI+ D +I P T PER + G + C A
Sbjct: 280 VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTT---PERIAQITGPPDRCQHAA 336
Query: 341 EEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQF 400
E I +R + PG G G GPP +
Sbjct: 337 EIITDLLRSVQAGNPGG--------PGPGGRGRG-----RGQGNWNMGPPGGL------- 376
Query: 401 EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIA--PAEAPDAKVRMVIITG 458
+ + +P G IIGK G+ IK +S+ +GA I++ P D +++ I G
Sbjct: 377 -----QEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRG 431
Query: 459 PPEAQFKAQGRIYGKI 474
P+ A+ I KI
Sbjct: 432 TPQQIDYARQLIEEKI 447
Score = 71.2 bits (173), Expect = 2e-12
Identities = 51/185 (27%), Positives = 89/185 (48%), Gaps = 7/185 (3%)
Query: 378 PTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGA 437
P + P + PP Q + T +P VG IIG+ G+ I ++ + +G
Sbjct: 73 PDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGC 132
Query: 438 SIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSP-----KEEVKLEAHI 492
I+IAP ++ R ++TG PE+ A+ R+ +I E+ +P I
Sbjct: 133 KIQIAP-DSGGLPERSCMLTGTPESVQSAK-RLLDQIVEKGRPAPGFHHGDGPGNAVQEI 190
Query: 493 RVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRK 552
+P+ AG VIGKGG+T+ +LQ + ++V+ +D + ++ITG Y Q A+
Sbjct: 191 MIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEM 250
Query: 553 IQEIL 557
+ E++
Sbjct: 251 VLELI 255
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 72.8 bits (177), Expect = 8e-13
Identities = 80/318 (25%), Positives = 148/318 (46%), Gaps = 56/318 (17%)
Query: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
L +RLL+ + VG+IIGK+G +++ + +++ ++I++ + G + I L+ P T+A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAGP--TNA 67
Query: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
K+ I+ K +DI + + L+++ + G LIGK G +K+I + T
Sbjct: 68 IFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIREST 127
Query: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES-------------YEN 353
++ ++ ++ + ER IT+ G ++ + ++I + ES +
Sbjct: 128 GAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSS 185
Query: 354 DIASMNLQAHLIPG---------LNLNALGL----FPPTSGMPPPTSGPPSAMTPPYPQF 400
+ QA+ I G L+ L + FP T G ++G ++
Sbjct: 186 PVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDAS-------- 237
Query: 401 EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIA-PAEAPDAKVRMVIITGP 459
++T + L IP +G IIG+QG I ++ + +GA IKIA P E + R V ITG
Sbjct: 238 --AQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG--STDRQVTITGS 293
Query: 460 PEAQFKAQGRIYGKIKEE 477
+ AQ I ++ E
Sbjct: 294 AASISLAQYLINVRLSSE 311
Score = 70.5 bits (171), Expect = 4e-12
Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ + GP A F
Sbjct: 13 TLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIF 69
Query: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 70 KAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGA 129
Query: 520 EVVVPRDQTPDENDQVV 536
+V V D P+ ++ +
Sbjct: 130 QVQVAGDMLPNSTERAI 146
Score = 30.4 bits (67), Expect = 4.7
Identities = 16/59 (27%), Positives = 31/59 (52%), Gaps = 2/59 (3%)
Query: 492 IRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQ 550
+ +P+ G +IG+ G +NE++ +S A++ + + QV ITG + +AQ
Sbjct: 245 LTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVT--ITGSAASISLAQ 301
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 72.0 bits (175), Expect = 1e-12
Identities = 42/137 (30%), Positives = 72/137 (52%), Gaps = 8/137 (5%)
Query: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ +TGP A F
Sbjct: 13 TLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPE---RIITLTGPTNAIF 69
Query: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 70 KAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGA 129
Query: 520 EVVVPRDQTPDENDQVV 536
+V V D P+ ++ +
Sbjct: 130 QVQVAGDMLPNSTERAI 146
Score = 58.5 bits (140), Expect = 2e-08
Identities = 80/388 (20%), Positives = 157/388 (40%), Gaps = 72/388 (18%)
Query: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
L +RLL+ + VG+IIGK+G +++ I +++ ++I++ + G + I L+ P T+A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI----SEGNCPERIITLTGP--TNA 67
Query: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
K+ I+ K +DI + + L+++ G LIGK G +K+I + T
Sbjct: 68 IFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIREST 127
Query: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEI----MKKIRESYENDIASMNLQ- 361
++ ++ ++ + ER IT+ G ++ + ++I ++ + +S + + ++ Q
Sbjct: 128 GAQVQVA--GDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQP 185
Query: 362 -AHLIPGLNLNALGLFPPTSGMPPPT---SGPPSAMTPPYPQFEQSETETVHLFIPALSV 417
P + +G P T GPP + + H P
Sbjct: 186 MPASSPVICAGGQDRCSDAAGYPHATHDLEGPP---------LDAYSIQGQHTISP---- 232
Query: 418 GAIIGKQGQHIKQLSRFA----GASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGK 473
+ K Q +Q S FA G + +P+ K
Sbjct: 233 -LDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVK----------------------- 268
Query: 474 IKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDEND 533
+ S + + +P+ G +IG+ G +NE++ +S A++ +
Sbjct: 269 ---GYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGR 325
Query: 534 QVVVKITGHFYACQVAQRKIQEILTQVK 561
QV ITG + +AQ I L+ K
Sbjct: 326 QVT--ITGSAASISLAQYLINARLSSEK 351
Score = 33.5 bits (75), Expect = 0.55
Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 156 DEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGS-VSKQKPCDLPLRLLVPTQFVGAIIGKE 214
+++A QQ+ G G SS G S L +P +G IIG++
Sbjct: 239 NQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQ 298
Query: 215 GATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAA 256
GA I I + + ++I + G++ + +TI + S A
Sbjct: 299 GANINEIRQMSGAQIKIANPVE-GSSGRQVTITGSAASISLA 339
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 70.9 bits (172), Expect = 3e-12
Identities = 55/202 (27%), Positives = 94/202 (46%), Gaps = 12/202 (5%)
Query: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338
LK+L + G +IGK G+ + +++++T I +S ++ ER ++G VE
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 339 AEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYP 398
I +KIRE +N +A + L P +N P S P + + P
Sbjct: 112 VHGFIAEKIREMPQN-VAKTEPVSILQPQTTVN------PDRIKQTLPSSPTTTKSSPSD 164
Query: 399 QFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDA---KVRMVI 455
S V + +P + G IIGK G +K + +GA +++ ++ PD + R+V
Sbjct: 165 PMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQL--SQKPDGINLQERVVT 222
Query: 456 ITGPPEAQFKAQGRIYGKIKEE 477
++G PE KA I KI+E+
Sbjct: 223 VSGEPEQNRKAVELIIQKIQED 244
Score = 57.4 bits (137), Expect = 4e-08
Identities = 62/234 (26%), Positives = 92/234 (39%), Gaps = 45/234 (19%)
Query: 373 LGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLS 432
+ L PP S P PP A + + + + IP+ + G+IIGK GQ I QL
Sbjct: 18 IDLDPPDS-RKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQ 76
Query: 433 RFAGASIKIAPAEA--PDAKVRMVIITGPPEAQFKAQGRIYGKIKE-ENFVSPKEEVKL- 488
+ GA+IK++ ++ P R+ +I G EA G I KI+E V+ E V +
Sbjct: 77 KETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSIL 136
Query: 489 ------------------------------------EAHIRVPSFAAGRVIGKGGKTVNE 512
+ I VP+ AG +IGKGG TV
Sbjct: 137 QPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKA 196
Query: 513 LQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQ 566
+ S A V + + + VV ++G RK E++ Q Q Q
Sbjct: 197 VMEQSGAWVQLSQKPDGINLQERVVTVSGE----PEQNRKAVELIIQKIQEDPQ 246
Score = 56.2 bits (134), Expect = 8e-08
Identities = 55/235 (23%), Positives = 100/235 (42%), Gaps = 53/235 (22%)
Query: 156 DEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEG 215
D +++ PL+ P + GS+++ + G + L++L+P+ G+IIGK G
Sbjct: 21 DPPDSRKRPLEAPP------EAGSTKRTNTGEDGQYF-----LKVLIPSYAAGSIIGKGG 69
Query: 216 ATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKF 273
TI + K+T + I + + ++ G E+ I T E +A I E + + Q++
Sbjct: 70 QTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAK 129
Query: 274 TEEIPL---------------------------------------KILAHNNFVGRLIGK 294
TE + + KI+ N+ G +IGK
Sbjct: 130 TEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGK 189
Query: 295 EGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRE 349
G +K + + + + +S + + ER +TV G E KA E I++KI+E
Sbjct: 190 GGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTVSGEPEQNRKAVELIIQKIQE 243
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/145 (23%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Query: 134 QALDKLNGFQLENFTLKVAYIPDEMAAQQN-PLQQPRGRRGLGQRGSSRQGSPGSVSKQK 192
+AL+ ++GF E K+ +P +A + + QP+ + + SP + +K
Sbjct: 107 EALNAVHGFIAE----KIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSP-TTTKSS 161
Query: 193 PCDL-------PLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKSI 244
P D ++++VP G IIGK GAT++ + +Q+ + + + +K + E+ +
Sbjct: 162 PSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVV 221
Query: 245 TILSTPEGTSAACKSILEIMHKEAQ 269
T+ PE A + I++ + ++ Q
Sbjct: 222 TVSGEPEQNRKAVELIIQKIQEDPQ 246
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 20/138 (14%)
Query: 428 IKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVK 487
I+Q G I + P PD++ R + PPEA G K N E+ +
Sbjct: 7 IQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGEDGQ 49
Query: 488 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVV--PRDQTPDENDQVVVKITGHFYA 545
+ +PS+AAG +IGKGG+T+ +LQ + A + + +D P ++V + I G A
Sbjct: 50 YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTVEA 108
Query: 546 CQVAQRKIQEILTQVKQH 563
I E + ++ Q+
Sbjct: 109 LNAVHGFIAEKIREMPQN 126
Score = 40.0 bits (92), Expect = 0.006
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSA 255
+ + VP VGAI+GK G T+ + T ++I + +K G + +TI TP T A
Sbjct: 424 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 483
Query: 256 A 256
A
Sbjct: 484 A 484
Score = 39.7 bits (91), Expect = 0.008
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 406 ETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAE--APDAKVRMVIITGPPEAQ 463
+ V + +P VGAI+GK G+ + + GA I+I+ P + R V ITG P A
Sbjct: 422 DVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAAT 481
Query: 464 FKAQGRIYGKIKEENFV 480
AQ I +I E V
Sbjct: 482 QAAQYLITQRITYEQGV 498
Score = 37.7 bits (86), Expect = 0.029
Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 492 IRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPR--DQTPDENDQVVVKITGHFYACQVA 549
I VP G ++GKGGKT+ E Q L+ A + + + + P ++ V ITG A Q A
Sbjct: 426 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT-ITGTPAATQAA 484
Query: 550 QRKIQEILT 558
Q I + +T
Sbjct: 485 QYLITQRIT 493
Score = 37.0 bits (84), Expect = 0.050
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338
++I N VG ++GK G+ L + ++ T +I IS E R +T+ G
Sbjct: 424 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 483
Query: 339 AEEEIMKKIRESYENDIASMNLQ 361
A+ I ++I +YE + + N Q
Sbjct: 484 AQYLITQRI--TYEQGVRAANPQ 504
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 70.9 bits (172), Expect = 3e-12
Identities = 81/321 (25%), Positives = 146/321 (45%), Gaps = 49/321 (15%)
Query: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
L +RLL+ + VG+IIGK+G +++ + +++ ++I++ + G + I L+ P T+A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAGP--TNA 67
Query: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
K+ I+ K +DI + + L+++ + G LIGK G +K+I + T
Sbjct: 68 IFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIREST 127
Query: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES-------------YEN 353
++ ++ ++ + ER IT+ G ++ + ++I + ES +
Sbjct: 128 GAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSS 185
Query: 354 DIASMNLQAHLIPG---------LNLNALGL----FPPT---SGMPPPTSGPPSAMTPPY 397
+ QA+ I G L+ L + FP T +G S P
Sbjct: 186 PVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWA 245
Query: 398 PQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIA-PAEAPDAKVRMVII 456
++T + L IP +G IIG+QG I ++ + +GA IKIA P E + R V I
Sbjct: 246 GLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG--STDRQVTI 303
Query: 457 TGPPEAQFKAQGRIYGKIKEE 477
TG + AQ I ++ E
Sbjct: 304 TGSAASISLAQYLINVRLSSE 324
Score = 70.5 bits (171), Expect = 4e-12
Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ + GP A F
Sbjct: 13 TLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIF 69
Query: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 70 KAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGA 129
Query: 520 EVVVPRDQTPDENDQVV 536
+V V D P+ ++ +
Sbjct: 130 QVQVAGDMLPNSTERAI 146
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 70.5 bits (171), Expect = 4e-12
Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ + GP A F
Sbjct: 13 TLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIF 69
Query: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 70 KAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGA 129
Query: 520 EVVVPRDQTPDENDQVV 536
+V V D P+ ++ +
Sbjct: 130 QVQVAGDMLPNSTERAI 146
Score = 68.6 bits (166), Expect = 2e-11
Identities = 80/325 (24%), Positives = 146/325 (44%), Gaps = 53/325 (16%)
Query: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
L +RLL+ + VG+IIGK+G +++ + +++ ++I++ + G + I L+ P T+A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAGP--TNA 67
Query: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
K+ I+ K +DI + + L+++ + G LIGK G +K+I + T
Sbjct: 68 IFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIREST 127
Query: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESY--------------- 351
++ ++ ++ + ER IT+ G ++ + ++I + E+
Sbjct: 128 GAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPK 185
Query: 352 --ENDIASMNLQAHLIPG---------LNLNALGL----FPPT---SGMPPPTSGPPSAM 393
+ + QA+ I G L+ L + FP T +G S P
Sbjct: 186 PSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 245
Query: 394 TPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIA-PAEAPDAKVR 452
++T + L IP +G IIG+QG I ++ + +GA IKIA P E + R
Sbjct: 246 GYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG--STDR 303
Query: 453 MVIITGPPEAQFKAQGRIYGKIKEE 477
V ITG + AQ I ++ E
Sbjct: 304 QVTITGSAASISLAQYLINVRLSSE 328
Score = 65.5 bits (158), Expect = 1e-10
Identities = 56/232 (24%), Positives = 98/232 (42%), Gaps = 48/232 (20%)
Query: 277 IPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETC 336
+ +++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAI 68
Query: 337 AKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPP 396
KA I+ K+ E + + + T+ PP
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNS--------------------TAASRPPV---------- 98
Query: 397 YPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVII 456
T+ L +PA G++IGK G IK++ GA +++A P++ R + I
Sbjct: 99 ----------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITI 148
Query: 457 TGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGK 508
G P++ + +I + E SP + V + P ++ VI GG+
Sbjct: 149 AGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 70.5 bits (171), Expect = 4e-12
Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ + GP A F
Sbjct: 13 TLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIF 69
Query: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 70 KAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGA 129
Query: 520 EVVVPRDQTPDENDQVV 536
+V V D P+ ++ +
Sbjct: 130 QVQVAGDMLPNSTERAI 146
Score = 63.5 bits (153), Expect = 5e-10
Identities = 49/186 (26%), Positives = 82/186 (44%), Gaps = 45/186 (24%)
Query: 277 IPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETC 336
+ +++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAI 68
Query: 337 AKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPP 396
KA I+ K+ E DI+S + T+ PP
Sbjct: 69 FKAFAMIIDKL----EEDISS----------------SMTNSTAASRPPV---------- 98
Query: 397 YPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVII 456
T+ L +PA G++IGK G IK++ GA +++A P++ R + I
Sbjct: 99 ----------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITI 148
Query: 457 TGPPEA 462
G P++
Sbjct: 149 AGIPQS 154
Score = 56.6 bits (135), Expect = 6e-08
Identities = 88/350 (25%), Positives = 149/350 (42%), Gaps = 77/350 (22%)
Query: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
L +RLL+ + VG+IIGK+G +++ + +++ ++I++ + G + I L+ P T+A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAGP--TNA 67
Query: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
K+ I+ K +DI + + L+++ + G LIGK G +K+I + T
Sbjct: 68 IFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIREST 127
Query: 307 DTK---------------ITISPLQE-----------LTLYNPERTITVKGNVETCAKAE 340
+ ITI+ + + + L +P + +T+ + +
Sbjct: 128 GAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
Query: 341 EEIMKKIRESYENDIASMN----------------LQAHLIPG---------LNLNALGL 375
+ R S +D AS L+A+ I G L+ L +
Sbjct: 188 IFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAM 247
Query: 376 ----FPPTSGMPPPTSGPPSAM--TPPYPQFEQSETETVH-LFIPALSVGAIIGKQGQHI 428
FP T G SG S+ Y + S T H L IP +G IIG+QG I
Sbjct: 248 QQSHFPMTHGNTG-FSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKI 306
Query: 429 KQLSRFAGASIKIA-PAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEE 477
++ + +GA IKIA P E + R V ITG + AQ I ++ E
Sbjct: 307 NEIRQMSGAQIKIANPVEG--STDRQVTITGSAASISLAQYLINVRLSSE 354
Score = 36.2 bits (82), Expect = 0.085
Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 10/127 (7%)
Query: 139 LNGFQLENFTLKVAYI---PD-----EMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSK 190
L G LE +T++ Y PD ++A QQ+ G G SS G
Sbjct: 218 LEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGL 277
Query: 191 QKPCDLPLR-LLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILST 249
L +P +G IIG++GA I I + + ++I + G+ ++ +TI +
Sbjct: 278 DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVTITGS 336
Query: 250 PEGTSAA 256
S A
Sbjct: 337 AASISLA 343
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 70.5 bits (171), Expect = 4e-12
Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ + GP A F
Sbjct: 13 TLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIF 69
Query: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 70 KAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGA 129
Query: 520 EVVVPRDQTPDENDQVV 536
+V V D P+ ++ +
Sbjct: 130 QVQVAGDMLPNSTERAI 146
Score = 54.3 bits (129), Expect = 3e-07
Identities = 80/398 (20%), Positives = 154/398 (38%), Gaps = 106/398 (26%)
Query: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
L +RLL+ + VG+IIGK+G +++ + +++ ++I++ + G + I L+ P T+A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAGP--TNA 67
Query: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
K+ I+ K +DI + + L+++ + G LIGK G +K+I + T
Sbjct: 68 IFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIREST 127
Query: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIP 366
++ ++ ++ + ER IT+ G ++ + ++I + E+
Sbjct: 128 GAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLETL--------------- 170
Query: 367 GLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQ 426
+ PP +T PY P S +I GQ
Sbjct: 171 -------------------SQSPPKGVTIPYR--------------PKPSSSPVIFAGGQ 197
Query: 427 HIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGR----------------- 469
R++ S + + + GPP + QG+
Sbjct: 198 -----DRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQ 252
Query: 470 ------IYGKIKEENFVSPKEEVK----LEA-------HIRVPSFAAGRVIGKGGKTVNE 512
+G S EVK L+A + +P+ G +IG+ G +NE
Sbjct: 253 QSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINE 312
Query: 513 LQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQ 550
++ +S A++ + + QV ITG + +AQ
Sbjct: 313 IRQMSGAQIKIANPVEGSTDRQVT--ITGSAASISLAQ 348
Score = 36.2 bits (82), Expect = 0.085
Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 10/127 (7%)
Query: 139 LNGFQLENFTLKVAYI---PD-----EMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSK 190
L G LE +T++ Y PD ++A QQ+ G G SS G
Sbjct: 222 LEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGL 281
Query: 191 QKPCDLPLR-LLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILST 249
L +P +G IIG++GA I I + + ++I + G+ ++ +TI +
Sbjct: 282 DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVTITGS 340
Query: 250 PEGTSAA 256
S A
Sbjct: 341 AASISLA 347
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 70.5 bits (171), Expect = 4e-12
Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ + GP A F
Sbjct: 13 TLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIF 69
Query: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 70 KAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGA 129
Query: 520 EVVVPRDQTPDENDQVV 536
+V V D P+ ++ +
Sbjct: 130 QVQVAGDMLPNSTERAI 146
Score = 63.5 bits (153), Expect = 5e-10
Identities = 49/186 (26%), Positives = 82/186 (44%), Gaps = 45/186 (24%)
Query: 277 IPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETC 336
+ +++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAI 68
Query: 337 AKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPP 396
KA I+ K+ E DI+S + T+ PP
Sbjct: 69 FKAFAMIIDKL----EEDISS----------------SMTNSTAASRPPV---------- 98
Query: 397 YPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVII 456
T+ L +PA G++IGK G IK++ GA +++A P++ R + I
Sbjct: 99 ----------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITI 148
Query: 457 TGPPEA 462
G P++
Sbjct: 149 AGIPQS 154
Score = 56.2 bits (134), Expect = 8e-08
Identities = 84/350 (24%), Positives = 147/350 (42%), Gaps = 76/350 (21%)
Query: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
L +RLL+ + VG+IIGK+G +++ + +++ ++I++ + G + I L+ P T+A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAGP--TNA 67
Query: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
K+ I+ K +DI + + L+++ + G LIGK G +K+I + T
Sbjct: 68 IFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIREST 127
Query: 307 DTK---------------ITISPLQE-----------LTLYNPERTITVKGNVETCAKAE 340
+ ITI+ + + + L +P + +T+ + +
Sbjct: 128 GAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
Query: 341 EEIMKKIRESYENDIASMN----------------LQAHLIPG---------LNLNALGL 375
+ R S +D AS L+A+ I G L+ L +
Sbjct: 188 IFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAM 247
Query: 376 ----FPPT---SGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHI 428
FP T +G S P ++T + L IP +G IIG+QG I
Sbjct: 248 QQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKI 307
Query: 429 KQLSRFAGASIKIA-PAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEE 477
++ + +GA IKIA P E + R V ITG + AQ I ++ E
Sbjct: 308 NEIRQMSGAQIKIANPVEG--STDRQVTITGSAASISLAQYLINVRLSSE 355
Score = 35.8 bits (81), Expect = 0.11
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 17/131 (12%)
Query: 139 LNGFQLENFTLKVAYI---PD-----EMAAQQNPLQQPRGRRGLGQRGSSRQGSPG---- 186
L G LE +T++ Y PD ++A QQ+ G G SS G
Sbjct: 218 LEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAG 277
Query: 187 -SVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSIT 245
S Q L +P +G IIG++GA I I + + ++I + G+ ++ +T
Sbjct: 278 LDASAQTTSH---ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVT 333
Query: 246 ILSTPEGTSAA 256
I + S A
Sbjct: 334 ITGSAASISLA 344
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 70.5 bits (171), Expect = 4e-12
Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ + GP A F
Sbjct: 13 TLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIF 69
Query: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 70 KAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGA 129
Query: 520 EVVVPRDQTPDENDQVV 536
+V V D P+ ++ +
Sbjct: 130 QVQVAGDMLPNSTERAI 146
Score = 53.9 bits (128), Expect = 4e-07
Identities = 80/399 (20%), Positives = 154/399 (38%), Gaps = 107/399 (26%)
Query: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
L +RLL+ + VG+IIGK+G +++ + +++ ++I++ + G + I L+ P T+A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAGP--TNA 67
Query: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
K+ I+ K +DI + + L+++ + G LIGK G +K+I + T
Sbjct: 68 IFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIREST 127
Query: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIP 366
++ ++ ++ + ER IT+ G ++ + ++I + E+
Sbjct: 128 GAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLETL--------------- 170
Query: 367 GLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQ 426
+ PP +T PY P S +I GQ
Sbjct: 171 -------------------SQSPPKGVTIPYR--------------PKPSSSPVIFAGGQ 197
Query: 427 HIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGR----------------- 469
R++ S + + + GPP + QG+
Sbjct: 198 -----DRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQ 252
Query: 470 ------IYGKIKEENFVSPKEEVK-----LEA-------HIRVPSFAAGRVIGKGGKTVN 511
+G S EVK L+A + +P+ G +IG+ G +N
Sbjct: 253 QSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKIN 312
Query: 512 ELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQ 550
E++ +S A++ + + QV ITG + +AQ
Sbjct: 313 EIRQMSGAQIKIANPVEGSTDRQVT--ITGSAASISLAQ 349
Score = 39.3 bits (90), Expect = 0.010
Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 403 SETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIA-PAEAPDAKVRMVIITGPPE 461
++T + L IP +G IIG+QG I ++ + +GA IKIA P E + R V ITG
Sbjct: 286 AQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG--STDRQVTITGSAA 343
Query: 462 AQFKAQGRIYGKIKEE 477
+ AQ I ++ E
Sbjct: 344 SISLAQYLINVRLSSE 359
Score = 35.8 bits (81), Expect = 0.11
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 17/131 (12%)
Query: 139 LNGFQLENFTLKVAYI---PD-----EMAAQQNPLQQPRGRRGLGQRGSSRQGSPG---- 186
L G LE +T++ Y PD ++A QQ+ G G SS G
Sbjct: 222 LEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAG 281
Query: 187 -SVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSIT 245
S Q L +P +G IIG++GA I I + + ++I + G+ ++ +T
Sbjct: 282 LDASAQTTSH---ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVT 337
Query: 246 ILSTPEGTSAA 256
I + S A
Sbjct: 338 ITGSAASISLA 348
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 66.6 bits (161), Expect = 6e-11
Identities = 62/210 (29%), Positives = 92/210 (43%), Gaps = 21/210 (10%)
Query: 373 LGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLS 432
+ L PP S P PP A + + + + IP+ + G+IIGK GQ I QL
Sbjct: 18 IDLDPPDS-RKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQ 76
Query: 433 RFAGASIKIAPAEA--PDAKVRMVIITGPPEAQFKAQGRIYGKIKE-ENFVSPKEEVKL- 488
+ GA+IK++ ++ P R+ +I G EA G I KI+E V+ E V +
Sbjct: 77 KETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSIL 136
Query: 489 ------------EAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVV 536
+ I VP+ AG +IGKGG TV + S A V + + + V
Sbjct: 137 QPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERV 196
Query: 537 VKITGHFYACQVAQRKIQEILTQVKQHQQQ 566
V ++G RK E++ Q Q Q
Sbjct: 197 VTVSGE----PEQNRKAVELIIQKIQEDPQ 222
Score = 65.5 bits (158), Expect = 1e-10
Identities = 55/211 (26%), Positives = 100/211 (47%), Gaps = 29/211 (13%)
Query: 156 DEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEG 215
D +++ PL+ P + GS+++ + G + L++L+P+ G+IIGK G
Sbjct: 21 DPPDSRKRPLEAPP------EAGSTKRTNTGEDGQYF-----LKVLIPSYAAGSIIGKGG 69
Query: 216 ATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKF 273
TI + K+T + I + + ++ G E+ I T E +A I E + + Q++
Sbjct: 70 QTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAK 129
Query: 274 TEEIPL---------------KILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQEL 318
TE + + KI+ N+ G +IGK G +K + + + + +S +
Sbjct: 130 TEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD- 188
Query: 319 TLYNPERTITVKGNVETCAKAEEEIMKKIRE 349
+ ER +TV G E KA E I++KI+E
Sbjct: 189 GINLQERVVTVSGEPEQNRKAVELIIQKIQE 219
Score = 61.2 bits (147), Expect = 2e-09
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 36/202 (17%)
Query: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338
LK+L + G +IGK G+ + +++++T I +S ++ ER ++G VE
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 339 AEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYP 398
I +KIRE +N + P S + P T+ P +
Sbjct: 112 VHGFIAEKIREMPQN-------------------VAKTEPVSILQPQTTVNPDRI----- 147
Query: 399 QFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDA---KVRMVI 455
+ V + +P + G IIGK G +K + +GA +++ ++ PD + R+V
Sbjct: 148 -------KQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQL--SQKPDGINLQERVVT 198
Query: 456 ITGPPEAQFKAQGRIYGKIKEE 477
++G PE KA I KI+E+
Sbjct: 199 VSGEPEQNRKAVELIIQKIQED 220
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 20/138 (14%)
Query: 428 IKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVK 487
I+Q G I + P PD++ R + PPEA G K N E+ +
Sbjct: 7 IQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGEDGQ 49
Query: 488 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVV--PRDQTPDENDQVVVKITGHFYA 545
+ +PS+AAG +IGKGG+T+ +LQ + A + + +D P ++V + I G A
Sbjct: 50 YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTVEA 108
Query: 546 CQVAQRKIQEILTQVKQH 563
I E + ++ Q+
Sbjct: 109 LNAVHGFIAEKIREMPQN 126
Score = 40.0 bits (92), Expect = 0.006
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSA 255
+ + VP VGAI+GK G T+ + T ++I + +K G + +TI TP T A
Sbjct: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
Query: 256 A 256
A
Sbjct: 460 A 460
Score = 39.7 bits (91), Expect = 0.008
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 406 ETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAE--APDAKVRMVIITGPPEAQ 463
+ V + +P VGAI+GK G+ + + GA I+I+ P + R V ITG P A
Sbjct: 398 DVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAAT 457
Query: 464 FKAQGRIYGKIKEENFV 480
AQ I +I E V
Sbjct: 458 QAAQYLITQRITYEQGV 474
Score = 37.7 bits (86), Expect = 0.029
Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 492 IRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPR--DQTPDENDQVVVKITGHFYACQVA 549
I VP G ++GKGGKT+ E Q L+ A + + + + P ++ V ITG A Q A
Sbjct: 402 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT-ITGTPAATQAA 460
Query: 550 QRKIQEILT 558
Q I + +T
Sbjct: 461 QYLITQRIT 469
Score = 37.0 bits (84), Expect = 0.050
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338
++I N VG ++GK G+ L + ++ T +I IS E R +T+ G
Sbjct: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
Query: 339 AEEEIMKKIRESYENDIASMNLQ 361
A+ I ++I +YE + + N Q
Sbjct: 460 AQYLITQRI--TYEQGVRAANPQ 480
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 66.2 bits (160), Expect = 8e-11
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 11/180 (6%)
Query: 391 SAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAK 450
S + P +P S TE +P VG IIG+ G+ I ++ + +G ++I+P ++
Sbjct: 132 SQLGPIHPPPRTSMTEEYR--VPDGMVGLIIGRGGEQINKIQQDSGCKVQISP-DSGGLP 188
Query: 451 VRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKE--------EVKLEAHIRVPSFAAGRV 502
R V +TG PE+ KA+ + + P + + I +P+ AG V
Sbjct: 189 ERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLV 248
Query: 503 IGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQ 562
IGKGG+T+ +LQ + ++++ +D + + N ++I G Y Q A + +IL + Q
Sbjct: 249 IGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQ 308
Score = 62.8 bits (151), Expect = 8e-10
Identities = 74/298 (24%), Positives = 122/298 (40%), Gaps = 60/298 (20%)
Query: 285 NNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIM 344
+ VG +IG+ G + KI+QD+ K+ ISP PER++++ G E+ KA+ +
Sbjct: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL---PERSVSLTGAPESVQKAKMML- 208
Query: 345 KKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSE 404
+DI S GPP + +
Sbjct: 209 --------DDIVSRG--------------------------RGGPPGQF---HDNANGGQ 231
Query: 405 TETVH-LFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKV-RMVIITGPPEA 462
TV + IPA G +IGK G+ IKQL AG + + + + V + + I G P
Sbjct: 232 NGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYK 291
Query: 463 QFKAQGRIYGKIKEEN---FVSPKE---EVKLEAHIRVPSFAAGRVIGKGGKTVNELQNL 516
+A + ++E + F E + + VP + G VIG+ G+ + ++QN
Sbjct: 292 VQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQN- 350
Query: 517 SSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQKALQSGPP 574
A V + Q + + I G C+ A R I ++L ++L+SGPP
Sbjct: 351 -DAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLL---------QSLRSGPP 398
Score = 62.4 bits (150), Expect = 1e-09
Identities = 85/363 (23%), Positives = 143/363 (39%), Gaps = 80/363 (22%)
Query: 161 QQNPLQQPRGRR--------GLGQRGSSRQGSPGSVSKQKPC--DLPLR----------- 199
Q N +QQ G + GL +R S G+P SV K K D+ R
Sbjct: 166 QINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHD 225
Query: 200 ------------LLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGA-AEKSITI 246
+++P G +IGK G TI+ + ++ K+ + + + +K + I
Sbjct: 226 NANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285
Query: 247 LSTPEGTSAACKSILEIMHKEAQD---------IKFTEEIPLKILAHNNFVGRLIGKEGR 297
+ P AC+ +++I+ + Q + I + + H+ VG +IG+ G
Sbjct: 286 IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHS--VGVVIGRSGE 343
Query: 298 NLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIAS 357
+KKI+ D +I ++ PE+ + G + C A I ND
Sbjct: 344 MIKKIQNDAGVRI---QFKQDDGTGPEKIAHIMGPPDRCEHAARII---------ND--- 388
Query: 358 MNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAM---TPPYPQFEQSETETVHLFIPA 414
L+ L G P GMPP G PP + S IP
Sbjct: 389 ------LLQSLRSGPPGP-PGGPGMPPGGRGRGRGQGNWGPPGGEMTFS--------IPT 433
Query: 415 LSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAP--DAKVRMVIITGPPEAQFKAQGRIYG 472
G +IG+ G+++K +++ GA ++I+ P D ++ II G P+ A+ I
Sbjct: 434 HKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE 493
Query: 473 KIK 475
KI+
Sbjct: 494 KIE 496
Score = 57.8 bits (138), Expect = 3e-08
Identities = 85/402 (21%), Positives = 147/402 (36%), Gaps = 89/402 (22%)
Query: 167 QPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQ 226
QP ++ L +G S G + + VP VG IIG+ G I I + +
Sbjct: 117 QPESKK-LASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSG 175
Query: 227 SKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIM-----------HKEAQDIKFTE 275
K+ + ++ G E+S+++ PE A + +I+ H A +
Sbjct: 176 CKVQIS-PDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGT 234
Query: 276 EIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTK-ITISPLQELTLYNPERTITVKGNVE 334
+ I A G +IGK G +K++++ K I I + T N ++ + + G+
Sbjct: 235 VQEIMIPAGK--AGLVIGKGGETIKQLQERAGVKMILIQDGSQNT--NVDKPLRIIGDPY 290
Query: 335 TCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMT 394
+A E +M +RE + N I G G+ P
Sbjct: 291 KVQQACEMVMDILRERDQGGFGDRNEYGSRIGG-------------GIDVP--------- 328
Query: 395 PPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMV 454
+P SVG +IG+ G+ IK++ AG I+ + + ++
Sbjct: 329 -----------------VPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPE-KIA 370
Query: 455 IITGPPEAQFKAQ--------------------------GRIYGKIKEENFVSPKEEVKL 488
I GPP+ A GR G+ + N+ P E+
Sbjct: 371 HIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGR-GQGNWGPPGGEMTF 429
Query: 489 EAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPD 530
+P+ G VIG+GG+ V + + A V + R P+
Sbjct: 430 S----IPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPN 467
Score = 37.7 bits (86), Expect = 0.029
Identities = 66/303 (21%), Positives = 103/303 (33%), Gaps = 60/303 (19%)
Query: 140 NGFQLENFTLKVAYIPDEMAAQQN-----PLQQPRGRRGLGQRGSSRQGSPGSVSKQKPC 194
+G Q N + I D QQ + + R + G G R G +
Sbjct: 272 DGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGI------ 325
Query: 195 DLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTS 254
D+P VP VG +IG+ G I+ I +I + + G EK I+ P+
Sbjct: 326 DVP----VPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGP-EKIAHIMGPPDRCE 380
Query: 255 AACKSILEIMHKEAQDIKFTE------------------------EIPLKILAHNNFVGR 290
A + I +++ E+ I H G
Sbjct: 381 HAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHK--CGL 438
Query: 291 LIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES 350
+IG+ G N+K I Q T + IS + ++G+ + A++ I +KI
Sbjct: 439 VIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI--- 495
Query: 351 YENDIASMNL------QAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPP------YP 398
E + + A + N PP G PP GPP PP YP
Sbjct: 496 -EGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPP--GAPPHAGGPPPHQYPPQGWGNTYP 552
Query: 399 QFE 401
Q++
Sbjct: 553 QWQ 555
>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 62.8 bits (151), Expect = 8e-10
Identities = 94/392 (23%), Positives = 163/392 (41%), Gaps = 69/392 (17%)
Query: 202 VPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSIL 261
+P + +IGK G ++++ +T +KI + R ++ I I T EG A +L
Sbjct: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD---PSNQIKITGTKEGIEKARHEVL 213
Query: 262 EIMHKEAQDIKFTEEIPLKILAHNNFVG---RLIGKEGRNLKKIEQDTDTKITISPLQEL 318
I QD + E + ++ H G RL+G +I Q+T T+I I P
Sbjct: 214 LI--SAEQDKRAVERLEVEKAFHPFIAGPYNRLVG-------EIMQETGTRINIPP---- 260
Query: 319 TLYNPERT-ITVKGNVETCAKAEEEIMKKIRESYENDIASMNL-----QAHLIPGLNLNA 372
+ RT I G E A+A I KKI E + ++ + Q + G N+
Sbjct: 261 --PSVNRTEIVFTGEKEQLAQAVARI-KKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNS 317
Query: 373 LGLFPPTSG----MPPPTS--------GPP----SAMTPPYPQFEQSETETVHLFIPALS 416
L +G +PP S G P A+T Y + +V P+
Sbjct: 318 LQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSV--AAPSWL 375
Query: 417 VGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKE 476
IIGK+GQ++ ++++ + I E D + + GP E AQ +I G +K+
Sbjct: 376 HRFIIGKKGQNLAKITQ-QMPKVHIEFTEGED----KITLEGPTEDVNVAQEQIEGMVKD 430
Query: 477 ----ENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDEN 532
++V + K H+ IGK G +N +++ V +P PD
Sbjct: 431 LINRMDYVEINIDHKFHRHL----------IGKSGANINRIKDQYKVSVRIP----PDSE 476
Query: 533 DQVVVKITGHFYACQVAQRKIQEILTQVKQHQ 564
+++I G Q A+R++ E+ ++++ +
Sbjct: 477 KSNLIRIEGDPQGVQQAKRELLELASRMENER 508
Score = 61.2 bits (147), Expect = 2e-09
Identities = 76/358 (21%), Positives = 140/358 (39%), Gaps = 75/358 (20%)
Query: 200 LLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKS 259
L++ +F IIG++G IR I + I A + I L P+ C
Sbjct: 512 LIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDP---AQKSDIVQLRGPKNEVEKCTK 568
Query: 260 ILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELT 319
++ M + + ++ +P+ H N +IGK G N+KKI ++++TKI + P +
Sbjct: 569 YMQKMVADLVENSYSISVPIFKQFHKN----IIGKGGANIKKIREESNTKIDL-PAEN-- 621
Query: 320 LYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPT 379
+ TI + G C A I+ S + D+A++
Sbjct: 622 --SNSETIIITGKRANCEAARSRIL-----SIQKDLANI--------------------- 653
Query: 380 SGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASI 439
V + IPA ++IG +G+ I+ + G
Sbjct: 654 --------------------------AEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVH 687
Query: 440 KIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAA 499
P E + V+I GP KA+ ++ +E K+ IR
Sbjct: 688 IHFPVEGSGSDT--VVIRGPSSDVEKAKKQLLHLAEE------KQTKSFTVDIRAKPEYH 739
Query: 500 GRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEIL 557
+IGKGG + ++++ + A V+ P ++ DQ ++ I G A + AQ++++ ++
Sbjct: 740 KFLIGKGGGKIRKVRDSTGARVIFP---AAEDKDQDLITIIGKEDAVREAQKELEALI 794
Score = 50.8 bits (120), Expect = 3e-06
Identities = 83/374 (22%), Positives = 150/374 (40%), Gaps = 64/374 (17%)
Query: 210 IIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQ 269
+IG +G +++ I ++T +++ ++ +++ + PE A + A+
Sbjct: 310 VIGPKGNSLQEILERTGVSVEIPPSDSIS---ETVILRGEPEKLGQALTEVY------AK 360
Query: 270 DIKFTEEIPLKILAHNNFVGR-LIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTIT 328
FT + +A +++ R +IGK+G+NL KI Q P + E IT
Sbjct: 361 ANSFT----VSSVAAPSWLHRFIIGKKGQNLAKITQQM-------PKVHIEFTEGEDKIT 409
Query: 329 VKGNVETCAKAEEEIMKKIRESYEN-DIASMNLQ----AHLI--PGLNLNALGLFPPTSG 381
++G E A+E+I +++ D +N+ HLI G N+N + S
Sbjct: 410 LEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSV 469
Query: 382 MPPPTS---------GPPSAMTPPYPQF-----EQSETETVHLFIPALSVGAIIGKQGQH 427
PP S G P + + T L I IIG++G+
Sbjct: 470 RIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGER 529
Query: 428 IKQL-SRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKE--ENFVSPKE 484
I+++ +F I P K +V + GP K + + + EN S
Sbjct: 530 IREIRDKFPEVIINFPD---PAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYS--- 583
Query: 485 EVKLEAHIRVPSFAA--GRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGH 542
I VP F +IGKGG + +++ S+ ++ +P + + E + ITG
Sbjct: 584 -------ISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE----TIIITGK 632
Query: 543 FYACQVAQRKIQEI 556
C+ A+ +I I
Sbjct: 633 RANCEAARSRILSI 646
Score = 48.1 bits (113), Expect = 2e-05
Identities = 45/171 (26%), Positives = 76/171 (44%), Gaps = 14/171 (8%)
Query: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAAC 257
L + V ++ IIG++GA I I + I K++ + ITI + T AA
Sbjct: 1055 LSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAAR 1114
Query: 258 KSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKI--EQDTDTKITISPL 315
+IL I+ + Q + +E++PL H R+IG G+ ++KI E D + S
Sbjct: 1115 DAILRIVGELEQMV--SEDVPLDHRVH----ARIIGARGKAIRKIMDEFKVDIRFPQSGA 1168
Query: 316 QELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIP 366
+ +TV G E +A + I+ E + + S LQ ++ P
Sbjct: 1169 PD------PNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKP 1213
Score = 34.7 bits (78), Expect = 0.25
Identities = 26/132 (19%), Positives = 62/132 (46%), Gaps = 17/132 (12%)
Query: 422 GKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVS 481
G+Q + ++ + GA ++++ A+ + +++G +A KA+ I ++
Sbjct: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSI---MVSGKLDAVMKARKDIVARL------- 147
Query: 482 PKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITG 541
+ + A + +P VIGK G+ + +L+ ++ ++ +PR P +KITG
Sbjct: 148 ---QTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQ----IKITG 200
Query: 542 HFYACQVAQRKI 553
+ A+ ++
Sbjct: 201 TKEGIEKARHEV 212
Score = 33.9 bits (76), Expect = 0.42
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 16/125 (12%)
Query: 420 IIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITG---PPEAQFKAQGRIYGKIKE 476
IIG++G I Q+ +I+ + + + ITG EA A RI G++
Sbjct: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGEL-- 1124
Query: 477 ENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVV 536
E VS E+V L+ + R+IG GK + ++ + ++ P+ PD N
Sbjct: 1125 EQMVS--EDVPLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN---C 1173
Query: 537 VKITG 541
V +TG
Sbjct: 1174 VTVTG 1178
>gi|42716280 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 62.8 bits (151), Expect = 8e-10
Identities = 94/392 (23%), Positives = 163/392 (41%), Gaps = 69/392 (17%)
Query: 202 VPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSIL 261
+P + +IGK G ++++ +T +KI + R ++ I I T EG A +L
Sbjct: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD---PSNQIKITGTKEGIEKARHEVL 213
Query: 262 EIMHKEAQDIKFTEEIPLKILAHNNFVG---RLIGKEGRNLKKIEQDTDTKITISPLQEL 318
I QD + E + ++ H G RL+G +I Q+T T+I I P
Sbjct: 214 LI--SAEQDKRAVERLEVEKAFHPFIAGPYNRLVG-------EIMQETGTRINIPP---- 260
Query: 319 TLYNPERT-ITVKGNVETCAKAEEEIMKKIRESYENDIASMNL-----QAHLIPGLNLNA 372
+ RT I G E A+A I KKI E + ++ + Q + G N+
Sbjct: 261 --PSVNRTEIVFTGEKEQLAQAVARI-KKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNS 317
Query: 373 LGLFPPTSG----MPPPTS--------GPP----SAMTPPYPQFEQSETETVHLFIPALS 416
L +G +PP S G P A+T Y + +V P+
Sbjct: 318 LQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSV--AAPSWL 375
Query: 417 VGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKE 476
IIGK+GQ++ ++++ + I E D + + GP E AQ +I G +K+
Sbjct: 376 HRFIIGKKGQNLAKITQ-QMPKVHIEFTEGED----KITLEGPTEDVNVAQEQIEGMVKD 430
Query: 477 ----ENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDEN 532
++V + K H+ IGK G +N +++ V +P PD
Sbjct: 431 LINRMDYVEINIDHKFHRHL----------IGKSGANINRIKDQYKVSVRIP----PDSE 476
Query: 533 DQVVVKITGHFYACQVAQRKIQEILTQVKQHQ 564
+++I G Q A+R++ E+ ++++ +
Sbjct: 477 KSNLIRIEGDPQGVQQAKRELLELASRMENER 508
Score = 61.2 bits (147), Expect = 2e-09
Identities = 76/358 (21%), Positives = 140/358 (39%), Gaps = 75/358 (20%)
Query: 200 LLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKS 259
L++ +F IIG++G IR I + I A + I L P+ C
Sbjct: 512 LIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDP---AQKSDIVQLRGPKNEVEKCTK 568
Query: 260 ILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELT 319
++ M + + ++ +P+ H N +IGK G N+KKI ++++TKI + P +
Sbjct: 569 YMQKMVADLVENSYSISVPIFKQFHKN----IIGKGGANIKKIREESNTKIDL-PAEN-- 621
Query: 320 LYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPT 379
+ TI + G C A I+ S + D+A++
Sbjct: 622 --SNSETIIITGKRANCEAARSRIL-----SIQKDLANI--------------------- 653
Query: 380 SGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASI 439
V + IPA ++IG +G+ I+ + G
Sbjct: 654 --------------------------AEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVH 687
Query: 440 KIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAA 499
P E + V+I GP KA+ ++ +E K+ IR
Sbjct: 688 IHFPVEGSGSDT--VVIRGPSSDVEKAKKQLLHLAEE------KQTKSFTVDIRAKPEYH 739
Query: 500 GRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEIL 557
+IGKGG + ++++ + A V+ P ++ DQ ++ I G A + AQ++++ ++
Sbjct: 740 KFLIGKGGGKIRKVRDSTGARVIFP---AAEDKDQDLITIIGKEDAVREAQKELEALI 794
Score = 50.8 bits (120), Expect = 3e-06
Identities = 83/374 (22%), Positives = 150/374 (40%), Gaps = 64/374 (17%)
Query: 210 IIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQ 269
+IG +G +++ I ++T +++ ++ +++ + PE A + A+
Sbjct: 310 VIGPKGNSLQEILERTGVSVEIPPSDSIS---ETVILRGEPEKLGQALTEVY------AK 360
Query: 270 DIKFTEEIPLKILAHNNFVGR-LIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTIT 328
FT + +A +++ R +IGK+G+NL KI Q P + E IT
Sbjct: 361 ANSFT----VSSVAAPSWLHRFIIGKKGQNLAKITQQM-------PKVHIEFTEGEDKIT 409
Query: 329 VKGNVETCAKAEEEIMKKIRESYEN-DIASMNLQ----AHLI--PGLNLNALGLFPPTSG 381
++G E A+E+I +++ D +N+ HLI G N+N + S
Sbjct: 410 LEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSV 469
Query: 382 MPPPTS---------GPPSAMTPPYPQF-----EQSETETVHLFIPALSVGAIIGKQGQH 427
PP S G P + + T L I IIG++G+
Sbjct: 470 RIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGER 529
Query: 428 IKQL-SRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKE--ENFVSPKE 484
I+++ +F I P K +V + GP K + + + EN S
Sbjct: 530 IREIRDKFPEVIINFPD---PAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYS--- 583
Query: 485 EVKLEAHIRVPSFAA--GRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGH 542
I VP F +IGKGG + +++ S+ ++ +P + + E + ITG
Sbjct: 584 -------ISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE----TIIITGK 632
Query: 543 FYACQVAQRKIQEI 556
C+ A+ +I I
Sbjct: 633 RANCEAARSRILSI 646
Score = 48.1 bits (113), Expect = 2e-05
Identities = 45/171 (26%), Positives = 76/171 (44%), Gaps = 14/171 (8%)
Query: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAAC 257
L + V ++ IIG++GA I I + I K++ + ITI + T AA
Sbjct: 1055 LSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAAR 1114
Query: 258 KSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKI--EQDTDTKITISPL 315
+IL I+ + Q + +E++PL H R+IG G+ ++KI E D + S
Sbjct: 1115 DAILRIVGELEQMV--SEDVPLDHRVH----ARIIGARGKAIRKIMDEFKVDIRFPQSGA 1168
Query: 316 QELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIP 366
+ +TV G E +A + I+ E + + S LQ ++ P
Sbjct: 1169 PD------PNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKP 1213
Score = 34.7 bits (78), Expect = 0.25
Identities = 26/132 (19%), Positives = 62/132 (46%), Gaps = 17/132 (12%)
Query: 422 GKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVS 481
G+Q + ++ + GA ++++ A+ + +++G +A KA+ I ++
Sbjct: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLSI---MVSGKLDAVMKARKDIVARL------- 147
Query: 482 PKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITG 541
+ + A + +P VIGK G+ + +L+ ++ ++ +PR P +KITG
Sbjct: 148 ---QTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQ----IKITG 200
Query: 542 HFYACQVAQRKI 553
+ A+ ++
Sbjct: 201 TKEGIEKARHEV 212
Score = 33.9 bits (76), Expect = 0.42
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 16/125 (12%)
Query: 420 IIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITG---PPEAQFKAQGRIYGKIKE 476
IIG++G I Q+ +I+ + + + ITG EA A RI G++
Sbjct: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGEL-- 1124
Query: 477 ENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVV 536
E VS E+V L+ + R+IG GK + ++ + ++ P+ PD N
Sbjct: 1125 EQMVS--EDVPLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN---C 1173
Query: 537 VKITG 541
V +TG
Sbjct: 1174 VTVTG 1178
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 61.6 bits (148), Expect = 2e-09
Identities = 51/200 (25%), Positives = 87/200 (43%), Gaps = 19/200 (9%)
Query: 385 PTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPA 444
P PP + + + + IP+ + G+IIGK GQ I QL + GA+IK++ +
Sbjct: 12 PLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKS 71
Query: 445 E--APDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEV--------------KL 488
+ P R+ ++ G EA I K++E K EV
Sbjct: 72 KDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAK 131
Query: 489 EAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQV 548
+A + VP+ AG +IGKGG TV + S A V + + + VV ++G +
Sbjct: 132 QAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGE---PEQ 188
Query: 549 AQRKIQEILTQVKQHQQQKA 568
+ + I+ +V++ Q +
Sbjct: 189 VHKAVSAIVQKVQEDPQSSS 208
Score = 59.7 bits (143), Expect = 7e-09
Identities = 44/169 (26%), Positives = 80/169 (47%), Gaps = 18/169 (10%)
Query: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSA 255
L++L+P+ G+IIGK G TI + K+T + I + + ++ G E+ + T E +A
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 256 ACKSILEIMHKEAQDIKFTEEIPL---------------KILAHNNFVGRLIGKEGRNLK 300
I E + + Q + E + + K++ N+ G +IGK G +K
Sbjct: 95 VHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVK 154
Query: 301 KIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRE 349
+ + + + +S E + ER +TV G E KA I++K++E
Sbjct: 155 AVMEQSGAWVQLSQKPE-GINLQERVVTVSGEPEQVHKAVSAIVQKVQE 202
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/103 (33%), Positives = 48/103 (46%), Gaps = 5/103 (4%)
Query: 458 GPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLS 517
GP A A G G + E + E K I VP G ++GKGGKT+ E Q L+
Sbjct: 379 GPLVAAAAAAGAAGGFLTAEKLAA--ESAKELVEIAVPENLVGAILGKGGKTLVEYQELT 436
Query: 518 SAEVVVPR--DQTPDENDQVVVKITGHFYACQVAQRKIQEILT 558
A + + + + P ++ V ITG A Q AQ I + +T
Sbjct: 437 GARIQISKKGEFLPGTRNRRVT-ITGSPAATQAAQYLISQRVT 478
Score = 41.6 bits (96), Expect = 0.002
Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 2/89 (2%)
Query: 402 QSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAE--APDAKVRMVIITGP 459
+S E V + +P VGAI+GK G+ + + GA I+I+ P + R V ITG
Sbjct: 403 ESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGS 462
Query: 460 PEAQFKAQGRIYGKIKEENFVSPKEEVKL 488
P A AQ I ++ E V K+
Sbjct: 463 PAATQAAQYLISQRVTYEQGVRASNPQKV 491
Score = 38.5 bits (88), Expect = 0.017
Identities = 32/120 (26%), Positives = 56/120 (46%), Gaps = 17/120 (14%)
Query: 445 EAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIG 504
EAPD++ R + PPE + + EE + + +PS+AAG +IG
Sbjct: 4 EAPDSRKRP--LETPPEVVCTKRS------------NTGEEGEYFLKVLIPSYAAGSIIG 49
Query: 505 KGGKTVNELQNLSSAEVVV--PRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQ 562
KGG+T+ +LQ + A + + +D P ++V + + G A I E + ++ Q
Sbjct: 50 KGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-VQGTAEALNAVHSFIAEKVREIPQ 108
Score = 38.1 bits (87), Expect = 0.022
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSA 255
+ + VP VGAI+GK G T+ + T ++I + +K G + +TI +P T A
Sbjct: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
Query: 256 A 256
A
Sbjct: 469 A 469
Score = 36.6 bits (83), Expect = 0.065
Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Query: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338
++I N VG ++GK G+ L + ++ T +I IS E R +T+ G+
Sbjct: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
Query: 339 AEEEIMKKIRESYENDIASMNLQ 361
A+ I +++ +YE + + N Q
Sbjct: 469 AQYLISQRV--TYEQGVRASNPQ 489
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 61.2 bits (147), Expect = 2e-09
Identities = 43/161 (26%), Positives = 83/161 (51%), Gaps = 10/161 (6%)
Query: 408 VHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQ 467
+ + +P +V IIG+QG +IKQL + GA I + + D R+++I+G P KA+
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE--RVLLISGFPVQVCKAK 112
Query: 468 GRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQ 527
I+ + E VS + + VP + GR+IG+GG+T+ + S A++ ++
Sbjct: 113 AAIHQILTENTPVSEQ--------LSVPQRSVGRIIGRGGETIRSICKASGAKITCDKES 164
Query: 528 TPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQKA 568
++KI+G A+ I E +++ ++ +++ A
Sbjct: 165 EGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIA 205
Score = 60.8 bits (146), Expect = 3e-09
Identities = 49/160 (30%), Positives = 80/160 (50%), Gaps = 14/160 (8%)
Query: 195 DLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTS 254
D+ + + VP + V IIG++GA I+ + KQT ++IDV E+ G E+ + I P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVD-TEDVG-DERVLLISGFPVQVC 109
Query: 255 AACKSILEIMHKEAQDIKFTEEIPL--KILAHNNFVGRLIGKEGRNLKKIEQDTDTKITI 312
A +I +I+ TE P+ ++ VGR+IG+ G ++ I + + KIT
Sbjct: 110 KAKAAIHQIL---------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITC 160
Query: 313 SPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYE 352
E TL R I + G + A A+ I++K+ E E
Sbjct: 161 DKESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 37.4 bits (85), Expect = 0.038
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
Query: 469 RIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQT 528
R Y + +EE E+ +E +RVP A +IG+ G + +L+ + A + V T
Sbjct: 35 RRYRESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DT 90
Query: 529 PDENDQVVVKITGHFYACQVAQRKIQEILTQ 559
D D+ V+ I+G A+ I +ILT+
Sbjct: 91 EDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
Score = 36.6 bits (83), Expect = 0.065
Identities = 50/247 (20%), Positives = 96/247 (38%), Gaps = 64/247 (25%)
Query: 254 SAACKSILEIMHKEAQDIKFT----EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTK 309
SA IL ++E+++ + T ++I +++ V +IG++G N+K++ + T +
Sbjct: 26 SATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR 85
Query: 310 ITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLN 369
I + + ER + + G KA+ I + + E+
Sbjct: 86 IDV----DTEDVGDERVLLISGFPVQVCKAKAAIHQILTEN------------------- 122
Query: 370 LNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIK 429
TP Q L +P SVG IIG+ G+ I+
Sbjct: 123 ------------------------TPVSEQ----------LSVPQRSVGRIIGRGGETIR 148
Query: 430 QLSRFAGASIKI-APAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKL 488
+ + +GA I +E R++ I+G + A+ I K+ E+ + ++ +
Sbjct: 149 SICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL--RKRIAH 206
Query: 489 EAHIRVP 495
A RVP
Sbjct: 207 SAETRVP 213
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 61.2 bits (147), Expect = 2e-09
Identities = 43/161 (26%), Positives = 83/161 (51%), Gaps = 10/161 (6%)
Query: 408 VHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQ 467
+ + +P +V IIG+QG +IKQL + GA I + + D R+++I+G P KA+
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE--RVLLISGFPVQVCKAK 112
Query: 468 GRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQ 527
I+ + E VS + + VP + GR+IG+GG+T+ + S A++ ++
Sbjct: 113 AAIHQILTENTPVSEQ--------LSVPQRSVGRIIGRGGETIRSICKASGAKITCDKES 164
Query: 528 TPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQKA 568
++KI+G A+ I E +++ ++ +++ A
Sbjct: 165 EGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIA 205
Score = 60.8 bits (146), Expect = 3e-09
Identities = 49/160 (30%), Positives = 80/160 (50%), Gaps = 14/160 (8%)
Query: 195 DLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTS 254
D+ + + VP + V IIG++GA I+ + KQT ++IDV E+ G E+ + I P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVD-TEDVG-DERVLLISGFPVQVC 109
Query: 255 AACKSILEIMHKEAQDIKFTEEIPL--KILAHNNFVGRLIGKEGRNLKKIEQDTDTKITI 312
A +I +I+ TE P+ ++ VGR+IG+ G ++ I + + KIT
Sbjct: 110 KAKAAIHQIL---------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITC 160
Query: 313 SPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYE 352
E TL R I + G + A A+ I++K+ E E
Sbjct: 161 DKESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 37.4 bits (85), Expect = 0.038
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
Query: 469 RIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQT 528
R Y + +EE E+ +E +RVP A +IG+ G + +L+ + A + V T
Sbjct: 35 RRYRESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DT 90
Query: 529 PDENDQVVVKITGHFYACQVAQRKIQEILTQ 559
D D+ V+ I+G A+ I +ILT+
Sbjct: 91 EDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
Score = 36.6 bits (83), Expect = 0.065
Identities = 50/247 (20%), Positives = 96/247 (38%), Gaps = 64/247 (25%)
Query: 254 SAACKSILEIMHKEAQDIKFT----EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTK 309
SA IL ++E+++ + T ++I +++ V +IG++G N+K++ + T +
Sbjct: 26 SATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR 85
Query: 310 ITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLN 369
I + + ER + + G KA+ I + + E+
Sbjct: 86 IDV----DTEDVGDERVLLISGFPVQVCKAKAAIHQILTEN------------------- 122
Query: 370 LNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIK 429
TP Q L +P SVG IIG+ G+ I+
Sbjct: 123 ------------------------TPVSEQ----------LSVPQRSVGRIIGRGGETIR 148
Query: 430 QLSRFAGASIKI-APAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKL 488
+ + +GA I +E R++ I+G + A+ I K+ E+ + ++ +
Sbjct: 149 SICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL--RKRIAH 206
Query: 489 EAHIRVP 495
A RVP
Sbjct: 207 SAETRVP 213
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 61.2 bits (147), Expect = 2e-09
Identities = 43/161 (26%), Positives = 83/161 (51%), Gaps = 10/161 (6%)
Query: 408 VHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQ 467
+ + +P +V IIG+QG +IKQL + GA I + + D R+++I+G P KA+
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE--RVLLISGFPVQVCKAK 112
Query: 468 GRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQ 527
I+ + E VS + + VP + GR+IG+GG+T+ + S A++ ++
Sbjct: 113 AAIHQILTENTPVSEQ--------LSVPQRSVGRIIGRGGETIRSICKASGAKITCDKES 164
Query: 528 TPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQKA 568
++KI+G A+ I E +++ ++ +++ A
Sbjct: 165 EGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIA 205
Score = 60.8 bits (146), Expect = 3e-09
Identities = 49/160 (30%), Positives = 80/160 (50%), Gaps = 14/160 (8%)
Query: 195 DLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTS 254
D+ + + VP + V IIG++GA I+ + KQT ++IDV E+ G E+ + I P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVD-TEDVG-DERVLLISGFPVQVC 109
Query: 255 AACKSILEIMHKEAQDIKFTEEIPL--KILAHNNFVGRLIGKEGRNLKKIEQDTDTKITI 312
A +I +I+ TE P+ ++ VGR+IG+ G ++ I + + KIT
Sbjct: 110 KAKAAIHQIL---------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITC 160
Query: 313 SPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYE 352
E TL R I + G + A A+ I++K+ E E
Sbjct: 161 DKESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 37.4 bits (85), Expect = 0.038
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
Query: 469 RIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQT 528
R Y + +EE E+ +E +RVP A +IG+ G + +L+ + A + V T
Sbjct: 35 RRYRESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DT 90
Query: 529 PDENDQVVVKITGHFYACQVAQRKIQEILTQ 559
D D+ V+ I+G A+ I +ILT+
Sbjct: 91 EDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
Score = 36.6 bits (83), Expect = 0.065
Identities = 50/247 (20%), Positives = 96/247 (38%), Gaps = 64/247 (25%)
Query: 254 SAACKSILEIMHKEAQDIKFT----EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTK 309
SA IL ++E+++ + T ++I +++ V +IG++G N+K++ + T +
Sbjct: 26 SATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR 85
Query: 310 ITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLN 369
I + + ER + + G KA+ I + + E+
Sbjct: 86 IDV----DTEDVGDERVLLISGFPVQVCKAKAAIHQILTEN------------------- 122
Query: 370 LNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIK 429
TP Q L +P SVG IIG+ G+ I+
Sbjct: 123 ------------------------TPVSEQ----------LSVPQRSVGRIIGRGGETIR 148
Query: 430 QLSRFAGASIKI-APAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKL 488
+ + +GA I +E R++ I+G + A+ I K+ E+ + ++ +
Sbjct: 149 SICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL--RKRIAH 206
Query: 489 EAHIRVP 495
A RVP
Sbjct: 207 SAETRVP 213
>gi|13899354 RNA binding motif protein 4B [Homo sapiens]
Length = 359
Score = 56.6 bits (135), Expect = 6e-08
Identities = 55/196 (28%), Positives = 83/196 (42%), Gaps = 19/196 (9%)
Query: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
M KL+IGNL A ++ S+F+ + + Y FV D++ A AI L
Sbjct: 1 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDII--KNYGFVHIEDKTAAEDAIRNLH-H 57
Query: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
+LHG I VE S K + KL + NI P + L + +YG V C+
Sbjct: 58 YKLHGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECD--------I 109
Query: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLG-QRGS 179
V + + ++A A++ + G F K ++ Q + R G+G Q G
Sbjct: 110 VKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHV-------QLSTSRLRTAPGMGDQSGC 162
Query: 180 SRQGSPGSVSKQKPCD 195
R G G SK+ P D
Sbjct: 163 YRCGKEGHWSKECPVD 178
>gi|93277122 RNA binding motif protein 4 [Homo sapiens]
Length = 364
Score = 56.2 bits (134), Expect = 8e-08
Identities = 55/196 (28%), Positives = 83/196 (42%), Gaps = 19/196 (9%)
Query: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
M KL+IGNL A ++ S+F+ + + Y FV D++ A AI L
Sbjct: 1 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDII--KNYGFVHIEDKTAAEDAIRNLH-H 57
Query: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
+LHG I VE S K + KL + NI P + L + +YG V C+
Sbjct: 58 YKLHGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECD--------I 109
Query: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLG-QRGS 179
V + + ++A A++ + G F K ++ Q + R G+G Q G
Sbjct: 110 VKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHV-------QLSTSRLRTAPGMGDQSGC 162
Query: 180 SRQGSPGSVSKQKPCD 195
R G G SK+ P D
Sbjct: 163 YRCGKEGHWSKECPID 178
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,358,369
Number of Sequences: 37866
Number of extensions: 1122019
Number of successful extensions: 6154
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 129
Number of HSP's that attempted gapping in prelim test: 5385
Number of HSP's gapped (non-prelim): 699
length of query: 579
length of database: 18,247,518
effective HSP length: 108
effective length of query: 471
effective length of database: 14,157,990
effective search space: 6668413290
effective search space used: 6668413290
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.