Guide to the Human Genome
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Search of human proteins with 30425464

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30425464 transmembrane protein 105 [Homo sapiens]
         (129 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30425464 transmembrane protein 105 [Homo sapiens]                  275   7e-75
gi|239740845 PREDICTED: hypothetical protein XP_002344070 [Homo ...    35   0.021
gi|239740737 PREDICTED: hypothetical protein [Homo sapiens]            35   0.021
gi|239740652 PREDICTED: hypothetical protein [Homo sapiens]            35   0.021
gi|11138123 cholinergic receptor, nicotinic, alpha 10 [Homo sapi...    33   0.081
gi|4505349 necdin [Homo sapiens]                                       31   0.24 
gi|239754312 PREDICTED: hypothetical protein XP_002345955 [Homo ...    31   0.31 
gi|239748874 PREDICTED: hypothetical protein XP_002346837 [Homo ...    31   0.31 
gi|239742903 PREDICTED: hypothetical protein XP_002342672 [Homo ...    31   0.31 
gi|169204521 PREDICTED: hypothetical protein [Homo sapiens]            30   0.40 
gi|169205149 PREDICTED: hypothetical protein [Homo sapiens]            30   0.40 
gi|169204400 PREDICTED: hypothetical protein [Homo sapiens]            30   0.40 
gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 ...    30   0.53 
gi|89886237 cyclin I family, member 2 [Homo sapiens]                   30   0.53 
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  29   0.90 
gi|239755452 PREDICTED: hypothetical protein [Homo sapiens]            29   0.90 
gi|239749933 PREDICTED: hypothetical protein XP_002347217 [Homo ...    29   0.90 
gi|239744256 PREDICTED: hypothetical protein XP_002343085 [Homo ...    29   0.90 
gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]         28   1.5  
gi|98961138 ZXD family zinc finger C isoform 2 [Homo sapiens]          28   1.5  
gi|98961133 ZXD family zinc finger C isoform 1 [Homo sapiens]          28   1.5  
gi|58218966 hypothetical protein LOC339201 [Homo sapiens]              28   1.5  
gi|149944548 neurobeachin-like 2 [Homo sapiens]                        28   2.0  
gi|171460922 transmembrane protein 132D [Homo sapiens]                 28   2.6  
gi|20162568 melanoma antigen family C, 3 isoform 1 [Homo sapiens]      28   2.6  
gi|29294655 melanoma antigen family C, 3 isoform 2 [Homo sapiens]      28   2.6  
gi|87116681 lysophosphatidylcholine acyltransferase 4 [Homo sapi...    27   3.4  
gi|55956910 meningioma  1 [Homo sapiens]                               27   3.4  
gi|134031945 SCO-spondin [Homo sapiens]                                27   3.4  
gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]          27   3.4  

>gi|30425464 transmembrane protein 105 [Homo sapiens]
          Length = 129

 Score =  275 bits (703), Expect = 7e-75
 Identities = 129/129 (100%), Positives = 129/129 (100%)

Query: 1   MLLKVRRASLKPPATPHQGAFRAGNVIGQLIYLLTWSLFTAWLRPPTLLQGPRTSPQGSP 60
           MLLKVRRASLKPPATPHQGAFRAGNVIGQLIYLLTWSLFTAWLRPPTLLQGPRTSPQGSP
Sbjct: 1   MLLKVRRASLKPPATPHQGAFRAGNVIGQLIYLLTWSLFTAWLRPPTLLQGPRTSPQGSP 60

Query: 61  PRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAGGLHLVPSSLSLAACGVVRMKGLW 120
           PRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAGGLHLVPSSLSLAACGVVRMKGLW
Sbjct: 61  PRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAGGLHLVPSSLSLAACGVVRMKGLW 120

Query: 121 GRGAGIRGR 129
           GRGAGIRGR
Sbjct: 121 GRGAGIRGR 129


>gi|239740845 PREDICTED: hypothetical protein XP_002344070 [Homo
           sapiens]
          Length = 222

 Score = 34.7 bits (78), Expect = 0.021
 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 19  GAFRAGNVIGQLIYLLTWSLFTAWLRPPTLLQGPRTSPQGSPPRSPWG 66
           GA+R G V+G    LL W  +T  +R P   +GP    +    R PWG
Sbjct: 169 GAYRGGGVLGTKPRLLGWGRYTLRVRGPGATEGPAFG-RDPGKRRPWG 215


>gi|239740737 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 147

 Score = 34.7 bits (78), Expect = 0.021
 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 19  GAFRAGNVIGQLIYLLTWSLFTAWLRPPTLLQGPRTSPQGSPPRSPWG 66
           GA+R G V+G    LL W  +T  +R P   +GP    +    R PWG
Sbjct: 94  GAYRGGGVLGTKPRLLGWGRYTLRVRGPGATEGPAFG-RDPGKRRPWG 140


>gi|239740652 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 196

 Score = 34.7 bits (78), Expect = 0.021
 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 19  GAFRAGNVIGQLIYLLTWSLFTAWLRPPTLLQGPRTSPQGSPPRSPWG 66
           GA+R G V+G    LL W  +T  +R P   +GP    +    R PWG
Sbjct: 143 GAYRGGGVLGTKPRLLGWGRYTLRVRGPGATEGPAFG-RDPGKRRPWG 189


>gi|11138123 cholinergic receptor, nicotinic, alpha 10 [Homo
           sapiens]
          Length = 450

 Score = 32.7 bits (73), Expect = 0.081
 Identities = 15/35 (42%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 44  RPPTLLQGPRTSPQGSPPRSPWGDCAEPSCLCEMK 78
           RPP L   P++   G+ P  P G C EP CLC  +
Sbjct: 361 RPPELSPSPQSPEGGAGP--PAGPCHEPRCLCRQE 393


>gi|4505349 necdin [Homo sapiens]
          Length = 321

 Score = 31.2 bits (69), Expect = 0.24
 Identities = 14/43 (32%), Positives = 20/43 (46%)

Query: 51 GPRTSPQGSPPRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSG 93
          GP  +PQ +PP     D  +P  L +     R H+ P+  Q G
Sbjct: 47 GPTAAPQAAPPPQAPNDEGDPKALQQAAEEGRAHQAPSAAQPG 89


>gi|239754312 PREDICTED: hypothetical protein XP_002345955 [Homo
           sapiens]
          Length = 127

 Score = 30.8 bits (68), Expect = 0.31
 Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 16/69 (23%)

Query: 43  LRPPTLLQGPRT-----SPQGSPPRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAG 97
           L PP  L+G  T      PQ SPP            + E + +R R  GPA  +S F  G
Sbjct: 10  LNPPHTLEGATTLALTRGPQASPPG-----------ILEPREKRGRDHGPARPRSAFFPG 58

Query: 98  GLHLVPSSL 106
                P SL
Sbjct: 59  ERRCPPGSL 67


>gi|239748874 PREDICTED: hypothetical protein XP_002346837 [Homo
           sapiens]
          Length = 127

 Score = 30.8 bits (68), Expect = 0.31
 Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 16/69 (23%)

Query: 43  LRPPTLLQGPRT-----SPQGSPPRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAG 97
           L PP  L+G  T      PQ SPP            + E + +R R  GPA  +S F  G
Sbjct: 10  LNPPHTLEGATTLALTRGPQASPPG-----------ILEPREKRGRDHGPARPRSAFFPG 58

Query: 98  GLHLVPSSL 106
                P SL
Sbjct: 59  ERRCPPGSL 67


>gi|239742903 PREDICTED: hypothetical protein XP_002342672 [Homo
           sapiens]
          Length = 127

 Score = 30.8 bits (68), Expect = 0.31
 Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 16/69 (23%)

Query: 43  LRPPTLLQGPRT-----SPQGSPPRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAG 97
           L PP  L+G  T      PQ SPP            + E + +R R  GPA  +S F  G
Sbjct: 10  LNPPHTLEGATTLALTRGPQASPPG-----------ILEPREKRGRDHGPARPRSAFFPG 58

Query: 98  GLHLVPSSL 106
                P SL
Sbjct: 59  ERRCPPGSL 67


>gi|169204521 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 430

 Score = 30.4 bits (67), Expect = 0.40
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 1/72 (1%)

Query: 56  PQGSPPRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAGGLHLVPSSLSLAACGVVR 115
           P+G  P  P   C E       + RRR HEG A G+    A      P++ +  A G  R
Sbjct: 311 PRGLAPHGPHPSCGERRPGGRWQQRRRSHEGRARGRHRVEADAADAAPTAAARRA-GRAR 369

Query: 116 MKGLWGRGAGIR 127
            +G   R  G R
Sbjct: 370 PRGRRHREHGTR 381


>gi|169205149 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 430

 Score = 30.4 bits (67), Expect = 0.40
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 1/72 (1%)

Query: 56  PQGSPPRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAGGLHLVPSSLSLAACGVVR 115
           P+G  P  P   C E       + RRR HEG A G+    A      P++ +  A G  R
Sbjct: 311 PRGLAPHGPHPSCGERRPGGRWQQRRRSHEGRARGRHRVEADAADAAPTAAARRA-GRAR 369

Query: 116 MKGLWGRGAGIR 127
            +G   R  G R
Sbjct: 370 PRGRRHREHGTR 381


>gi|169204400 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 430

 Score = 30.4 bits (67), Expect = 0.40
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 1/72 (1%)

Query: 56  PQGSPPRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAGGLHLVPSSLSLAACGVVR 115
           P+G  P  P   C E       + RRR HEG A G+    A      P++ +  A G  R
Sbjct: 311 PRGLAPHGPHPSCGERRPGGRWQQRRRSHEGRARGRHRVEADAADAAPTAAARRA-GRAR 369

Query: 116 MKGLWGRGAGIR 127
            +G   R  G R
Sbjct: 370 PRGRRHREHGTR 381


>gi|239756926 PREDICTED: similar to TBC1 domain family, member 3
           [Homo sapiens]
          Length = 424

 Score = 30.0 bits (66), Expect = 0.53
 Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 13/60 (21%)

Query: 6   RRASLKPPATPHQGAFRAGNVIGQLIYLLTWSLFTAWLRPPTLLQGPRTSPQGSPPRSPW 65
           ++  L PPA P QG+  +  V              A     TL +G R +P G P R PW
Sbjct: 228 KQGDLPPPAKPEQGSSASRPV-------------PASRGGKTLCKGDRQAPPGPPARFPW 274


>gi|89886237 cyclin I family, member 2 [Homo sapiens]
          Length = 369

 Score = 30.0 bits (66), Expect = 0.53
 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%)

Query: 50  QGPRTSPQGSPPRSPWGDCAEPSCLCEMKIRRRRHEGPAW 89
           Q PR +PQ   PR+  GD  E   LC +++ + R E   W
Sbjct: 99  QAPRPAPQSRKPRNLEGDLDERRLLCHLQLAQDR-EARLW 137


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 29.3 bits (64), Expect = 0.90
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 49   LQGPRTSPQGSPPRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAGGLHLVPSSLSL 108
            L GP T    +  R P G+ A+P    E    R+R  GP+ G++G     L  V +S +L
Sbjct: 1066 LSGPVTGLLATARRGP-GESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATL 1124


>gi|239755452 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 171

 Score = 29.3 bits (64), Expect = 0.90
 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 12/49 (24%)

Query: 21  FRAGNVIG----QLIYLLTWSLFTAWLRPPTLLQGPRTSPQGSPPRSPW 65
           F  G V G    Q +YLL W        PP LL+G   + Q  P R+PW
Sbjct: 127 FPKGQVWGCWCPQHVYLLLW--------PPGLLRGEGVAIQPPPYRAPW 167


>gi|239749933 PREDICTED: hypothetical protein XP_002347217 [Homo
           sapiens]
          Length = 171

 Score = 29.3 bits (64), Expect = 0.90
 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 12/49 (24%)

Query: 21  FRAGNVIG----QLIYLLTWSLFTAWLRPPTLLQGPRTSPQGSPPRSPW 65
           F  G V G    Q +YLL W        PP LL+G   + Q  P R+PW
Sbjct: 127 FPKGQVWGCWCPQHVYLLLW--------PPGLLRGEGVAIQPPPYRAPW 167


>gi|239744256 PREDICTED: hypothetical protein XP_002343085 [Homo
           sapiens]
          Length = 171

 Score = 29.3 bits (64), Expect = 0.90
 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 12/49 (24%)

Query: 21  FRAGNVIG----QLIYLLTWSLFTAWLRPPTLLQGPRTSPQGSPPRSPW 65
           F  G V G    Q +YLL W        PP LL+G   + Q  P R+PW
Sbjct: 127 FPKGQVWGCWCPQHVYLLLW--------PPGLLRGEGVAIQPPPYRAPW 167


>gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]
          Length = 544

 Score = 28.5 bits (62), Expect = 1.5
 Identities = 28/100 (28%), Positives = 35/100 (35%), Gaps = 19/100 (19%)

Query: 47  TLLQGPRTSPQGSP----------------PRSPWGDCAEPSCLCEMKIRRRRHEGPAWG 90
           T +QGPR  PQ SP                PR       + + L   +      E P   
Sbjct: 381 TPVQGPRPRPQSSPGHDPAEHESPRAAKNVPRQNSAPLLQTALLGNGERPPGAKEAPPLT 440

Query: 91  QSGFLAGGLHLVPSSLSLAACGVVR---MKGLWGRGAGIR 127
            S     G    PS  S AA  V     ++G W RG G+R
Sbjct: 441 LSLVKPSGRGAAPSLTSQAAAQVANQALIRGDWNRGGGVR 480


>gi|98961138 ZXD family zinc finger C isoform 2 [Homo sapiens]
          Length = 710

 Score = 28.5 bits (62), Expect = 1.5
 Identities = 11/22 (50%), Positives = 13/22 (59%)

Query: 52  PRTSPQGSPPRSPWGDCAEPSC 73
           PR +PQ S P +P   C EP C
Sbjct: 161 PRRAPQASGPSTPGYRCPEPQC 182


>gi|98961133 ZXD family zinc finger C isoform 1 [Homo sapiens]
          Length = 858

 Score = 28.5 bits (62), Expect = 1.5
 Identities = 11/22 (50%), Positives = 13/22 (59%)

Query: 52  PRTSPQGSPPRSPWGDCAEPSC 73
           PR +PQ S P +P   C EP C
Sbjct: 161 PRRAPQASGPSTPGYRCPEPQC 182


>gi|58218966 hypothetical protein LOC339201 [Homo sapiens]
          Length = 193

 Score = 28.5 bits (62), Expect = 1.5
 Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 27/81 (33%)

Query: 49  LQGPRTSPQGS--PPRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAGGLHLVPSSL 106
           + GP ++PQG+   PRSP              +RR+  + P+WG  G         P++ 
Sbjct: 1   MSGPPSAPQGALAAPRSP-------------AVRRKGLQAPSWGSPG--------RPAAH 39

Query: 107 SLAACGVVRMKGLWGRGAGIR 127
           S  ACG       WG   G R
Sbjct: 40  SPWACGPPH----WGPQRGPR 56


>gi|149944548 neurobeachin-like 2 [Homo sapiens]
          Length = 2754

 Score = 28.1 bits (61), Expect = 2.0
 Identities = 15/33 (45%), Positives = 20/33 (60%), Gaps = 1/33 (3%)

Query: 40   TAWLRPPTLLQGPRTSPQGSPPRSPWGDCAEPS 72
            TA   PP+  + P TSP+ +PP+ P    AEPS
Sbjct: 1298 TAGSPPPSSPESP-TSPKPAPPKPPTESPAEPS 1329


>gi|171460922 transmembrane protein 132D [Homo sapiens]
          Length = 1099

 Score = 27.7 bits (60), Expect = 2.6
 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 11/42 (26%)

Query: 38  LFTAWLRPPTLLQGPRTS---PQGSP--------PRSPWGDC 68
           L ++W  PPT++ G R S   P+G+P        P    GDC
Sbjct: 198 LLSSWFSPPTVVAGRRKSVDQPEGTPVELYYTVHPGGERGDC 239


>gi|20162568 melanoma antigen family C, 3 isoform 1 [Homo sapiens]
          Length = 643

 Score = 27.7 bits (60), Expect = 2.6
 Identities = 12/23 (52%), Positives = 15/23 (65%), Gaps = 3/23 (13%)

Query: 52  PRTSPQG---SPPRSPWGDCAEP 71
           P+ SPQG   SPP+SP   C+ P
Sbjct: 400 PKISPQGPPQSPPQSPLDSCSSP 422


>gi|29294655 melanoma antigen family C, 3 isoform 2 [Homo sapiens]
          Length = 346

 Score = 27.7 bits (60), Expect = 2.6
 Identities = 12/23 (52%), Positives = 15/23 (65%), Gaps = 3/23 (13%)

Query: 52  PRTSPQG---SPPRSPWGDCAEP 71
           P+ SPQG   SPP+SP   C+ P
Sbjct: 102 PKISPQGPPQSPPQSPLDSCSSP 124


>gi|87116681 lysophosphatidylcholine acyltransferase 4 [Homo
           sapiens]
          Length = 524

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 11/27 (40%), Positives = 16/27 (59%)

Query: 38  LFTAWLRPPTLLQGPRTSPQGSPPRSP 64
           LF+ +LRPP   +G   +P  S P +P
Sbjct: 482 LFSTYLRPPHTSRGTSQTPNASSPGNP 508


>gi|55956910 meningioma  1 [Homo sapiens]
          Length = 1320

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 3/60 (5%)

Query: 45  PPTLLQGPRTSPQGSPPRSPWGDCAEPSCLCEMKIRRRRHEGPAWGQSGFLAGGLHLVPS 104
           PP   Q P+  PQ  PP  P     + SC   +    R  +G A   SG L  G  ++PS
Sbjct: 346 PPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALP---RPQQGEAGTPSGGLQDGGPMLPS 402


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 2/39 (5%)

Query: 63   SPWGDCAEPSCLCEMKIRRRRHEGPAWGQS-GFLAGGLH 100
            SPW  C+EP C   M  +R+ H     G++   L GGLH
Sbjct: 1757 SPWSVCSEP-CRGTMTRQRQCHSPQNGGRTCAALPGGLH 1794


>gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
          Length = 845

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 9/73 (12%)

Query: 2   LLKVRRASLKPPATPHQGAFRAGNVIGQLIYLLTWSLFTAWL-RPPTLLQGPRT--SPQG 58
           +++++ +  +PP+T    +  AG   G       W+  T+ + RPP   QGP T  S  G
Sbjct: 446 VIEIQVSEQEPPSTDVPPSPEAGGTTGP------WTSTTSEVPRPPEPSQGPSTTSSGGG 499

Query: 59  SPPRSPWGDCAEP 71
           + P  P G    P
Sbjct: 500 TGPHPPSGTTLRP 512


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.140    0.476 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,517,093
Number of Sequences: 37866
Number of extensions: 336989
Number of successful extensions: 1178
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 1140
Number of HSP's gapped (non-prelim): 80
length of query: 129
length of database: 18,247,518
effective HSP length: 90
effective length of query: 39
effective length of database: 14,839,578
effective search space: 578743542
effective search space used: 578743542
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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