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Search of human proteins with 29789443
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29789443 Ras association (RalGDS/AF-6) domain family 6
isoform a [Homo sapiens]
(337 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isofor... 669 0.0
gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isofor... 669 0.0
gi|25777677 Ras association domain family 2 [Homo sapiens] 229 2e-60
gi|7661964 Ras association domain family 2 [Homo sapiens] 229 2e-60
gi|23510360 Ras association domain family 4 [Homo sapiens] 196 2e-50
gi|25777684 Ras association domain family 1 isoform D [Homo sapi... 59 6e-09
gi|25777682 Ras association domain family 1 isoform C [Homo sapi... 59 6e-09
gi|20149588 Ras association domain family 1 isoform A [Homo sapi... 59 6e-09
gi|25777680 Ras association domain family 1 isoform B [Homo sapi... 59 6e-09
gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isofor... 56 4e-08
gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isofor... 56 4e-08
gi|30039698 Ras association (RalGDS/AF-6) domain family member 3... 41 0.002
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 36 0.043
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 35 0.073
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 34 0.21
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora... 34 0.21
gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isofor... 33 0.28
gi|157502184 kinesin family member 6 [Homo sapiens] 33 0.36
gi|55769587 probable nucleolar complex protein 14 [Homo sapiens] 33 0.47
gi|239755855 PREDICTED: hypothetical protein [Homo sapiens] 32 0.62
gi|239750363 PREDICTED: hypothetical protein XP_002347382 [Homo ... 32 0.62
gi|239744667 PREDICTED: hypothetical protein XP_002343220 [Homo ... 32 0.62
gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7... 32 0.62
gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7... 32 0.62
gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6... 32 0.62
gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5... 32 0.62
gi|148612801 KIAA1009 protein [Homo sapiens] 32 0.81
gi|4758646 kinesin family member 3B [Homo sapiens] 32 1.1
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 31 1.8
gi|169167074 PREDICTED: similar to SET translocation [Homo sapiens] 30 2.3
>gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isoform b
[Homo sapiens]
Length = 369
Score = 669 bits (1727), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 1 MTMMAHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGML 60
MTMMAHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGML
Sbjct: 33 MTMMAHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGML 92
Query: 61 DIFWGVKRPIQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMS 120
DIFWGVKRPIQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMS
Sbjct: 93 DIFWGVKRPIQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMS 152
Query: 121 EKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRAS 180
EKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRAS
Sbjct: 153 EKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRAS 212
Query: 181 INGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATG 240
INGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATG
Sbjct: 213 INGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATG 272
Query: 241 EQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLN 300
EQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLN
Sbjct: 273 EQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLN 332
Query: 301 EEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV 337
EEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV
Sbjct: 333 EEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV 369
>gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isoform a
[Homo sapiens]
Length = 337
Score = 669 bits (1727), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 1 MTMMAHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGML 60
MTMMAHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGML
Sbjct: 1 MTMMAHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGML 60
Query: 61 DIFWGVKRPIQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMS 120
DIFWGVKRPIQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMS
Sbjct: 61 DIFWGVKRPIQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMS 120
Query: 121 EKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRAS 180
EKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRAS
Sbjct: 121 EKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRAS 180
Query: 181 INGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATG 240
INGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATG
Sbjct: 181 INGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATG 240
Query: 241 EQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLN 300
EQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLN
Sbjct: 241 EQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLN 300
Query: 301 EEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV 337
EEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV
Sbjct: 301 EEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV 337
>gi|25777677 Ras association domain family 2 [Homo sapiens]
Length = 326
Score = 229 bits (585), Expect = 2e-60
Identities = 136/338 (40%), Positives = 215/338 (63%), Gaps = 20/338 (5%)
Query: 5 AHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGMLDIFW 64
+HQ S + + +I++ +L LKTYN++YE Q NL + + E ED + IVEG+L+I W
Sbjct: 4 SHQ-TSLVPCGQDKYISKNELLLHLKTYNLYYEGQ-NLQLRHREEED-EFIVEGLLNISW 60
Query: 65 GVKRPIQLKIQDE----KPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMS 120
G++RPI+L++QD+ +P S +S S ++G T +ISE+D P
Sbjct: 61 GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAP--PEG 118
Query: 121 EKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRAS 180
++ S D S LKP + D+P L RT S+ + R+ D++ +++R S
Sbjct: 119 DQMPSSTD-----SRGLKPL---QEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFS 170
Query: 181 INGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATG 240
INGHFYNH+TS+F PA+ S T VR+NS M T +V+K LL KFKIENS ++FAL+++ +G
Sbjct: 171 INGHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSG 230
Query: 241 EQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKD-AEEISSDVAQYINFHFSLLESILQRL 299
E+++LK TD PL+ R+LQGP E+ +++FLM+KD EE++ DVAQYI F +L+S +Q+L
Sbjct: 231 EKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKL 290
Query: 300 NEEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV 337
EEE RE+++++ K+ + +I + L+ + +T T+
Sbjct: 291 QEEEDREVKKLMRKYTVLRLMIRQRLEE--IAETPATI 326
>gi|7661964 Ras association domain family 2 [Homo sapiens]
Length = 326
Score = 229 bits (585), Expect = 2e-60
Identities = 136/338 (40%), Positives = 215/338 (63%), Gaps = 20/338 (5%)
Query: 5 AHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGMLDIFW 64
+HQ S + + +I++ +L LKTYN++YE Q NL + + E ED + IVEG+L+I W
Sbjct: 4 SHQ-TSLVPCGQDKYISKNELLLHLKTYNLYYEGQ-NLQLRHREEED-EFIVEGLLNISW 60
Query: 65 GVKRPIQLKIQDE----KPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMS 120
G++RPI+L++QD+ +P S +S S ++G T +ISE+D P
Sbjct: 61 GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAP--PEG 118
Query: 121 EKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRAS 180
++ S D S LKP + D+P L RT S+ + R+ D++ +++R S
Sbjct: 119 DQMPSSTD-----SRGLKPL---QEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFS 170
Query: 181 INGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATG 240
INGHFYNH+TS+F PA+ S T VR+NS M T +V+K LL KFKIENS ++FAL+++ +G
Sbjct: 171 INGHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSG 230
Query: 241 EQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKD-AEEISSDVAQYINFHFSLLESILQRL 299
E+++LK TD PL+ R+LQGP E+ +++FLM+KD EE++ DVAQYI F +L+S +Q+L
Sbjct: 231 EKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKL 290
Query: 300 NEEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV 337
EEE RE+++++ K+ + +I + L+ + +T T+
Sbjct: 291 QEEEDREVKKLMRKYTVLRLMIRQRLEE--IAETPATI 326
>gi|23510360 Ras association domain family 4 [Homo sapiens]
Length = 321
Score = 196 bits (499), Expect = 2e-50
Identities = 124/339 (36%), Positives = 197/339 (58%), Gaps = 42/339 (12%)
Query: 10 SWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGMLDIFWGVKRP 69
S + I++ I + +L LLKTYN ++E K+ + + E E+G LI+EG+L+I WG++RP
Sbjct: 9 SHVPISDSKSIQKSELLGLLKTYNCYHEG-KSFQLRHRE-EEGTLIIEGLLNIAWGLRRP 66
Query: 70 IQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMSEKRNSQEDY 129
I+L++QD++ + + S+ M R R P+ E + Q
Sbjct: 67 IRLQMQDDR--------EQVHLPSTSWMPR--------------RPSCPLKEP-SPQNGN 103
Query: 130 LSYHSNTLKPHAKDEP------------DSPVLYRTMSEAALVRKRMKPLMMDRKERQK- 176
++ +++P K E ++P L RT S+A+ + +R +P E Q+
Sbjct: 104 ITAQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQR-RPKCRAPGEAQRI 162
Query: 177 --NRASINGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALH 234
+R SINGHFYNH+TS+F PA+ S T VRVNS M T +V+ LL KF++E+ P +FAL+
Sbjct: 163 RRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALY 222
Query: 235 IIFATGEQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKD-AEEISSDVAQYINFHFSLLE 293
I+ +GE+ +LK + PL+ R+L GP EK ARIFLM+ D E+ +VAQYI F +L+
Sbjct: 223 IVHESGERTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLD 282
Query: 294 SILQRLNEEEKREIQRIVTKFNKEKAIILKCLQNKLVIK 332
S +++L EEE+REI ++ KF + +L+ L+ + K
Sbjct: 283 SFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEAK 321
>gi|25777684 Ras association domain family 1 isoform D [Homo
sapiens]
Length = 344
Score = 58.9 bits (141), Expect = 6e-09
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 15/139 (10%)
Query: 183 GHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ 242
G TS ++P ++ + V S R EVI+ LL+KF + + P+ FAL F E+
Sbjct: 199 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFAL---FERAER 254
Query: 243 ------RRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESIL 296
R+L + PL RLL GPS+K L + D+ E++ D F L + L
Sbjct: 255 HGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDA-----FSMPELHNFL 309
Query: 297 QRLNEEEKREIQRIVTKFN 315
+ L EE+ +++I+ K++
Sbjct: 310 RILQREEEEHLRQILQKYS 328
>gi|25777682 Ras association domain family 1 isoform C [Homo
sapiens]
Length = 270
Score = 58.9 bits (141), Expect = 6e-09
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 15/139 (10%)
Query: 183 GHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ 242
G TS ++P ++ + V S R EVI+ LL+KF + + P+ FAL F E+
Sbjct: 125 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFAL---FERAER 180
Query: 243 ------RRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESIL 296
R+L + PL RLL GPS+K L + D+ E++ D F L + L
Sbjct: 181 HGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDA-----FSMPELHNFL 235
Query: 297 QRLNEEEKREIQRIVTKFN 315
+ L EE+ +++I+ K++
Sbjct: 236 RILQREEEEHLRQILQKYS 254
>gi|20149588 Ras association domain family 1 isoform A [Homo
sapiens]
Length = 340
Score = 58.9 bits (141), Expect = 6e-09
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 15/139 (10%)
Query: 183 GHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ 242
G TS ++P ++ + V S R EVI+ LL+KF + + P+ FAL F E+
Sbjct: 195 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFAL---FERAER 250
Query: 243 ------RRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESIL 296
R+L + PL RLL GPS+K L + D+ E++ D F L + L
Sbjct: 251 HGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDA-----FSMPELHNFL 305
Query: 297 QRLNEEEKREIQRIVTKFN 315
+ L EE+ +++I+ K++
Sbjct: 306 RILQREEEEHLRQILQKYS 324
>gi|25777680 Ras association domain family 1 isoform B [Homo
sapiens]
Length = 189
Score = 58.9 bits (141), Expect = 6e-09
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 15/139 (10%)
Query: 183 GHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ 242
G TS ++P ++ + V S R EVI+ LL+KF + + P+ FAL F E+
Sbjct: 44 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFAL---FERAER 99
Query: 243 ------RRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESIL 296
R+L + PL RLL GPS+K L + D+ E++ D F L + L
Sbjct: 100 HGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDA-----FSMPELHNFL 154
Query: 297 QRLNEEEKREIQRIVTKFN 315
+ L EE+ +++I+ K++
Sbjct: 155 RILQREEEEHLRQILQKYS 173
>gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isoform C
[Homo sapiens]
Length = 265
Score = 56.2 bits (134), Expect = 4e-08
Identities = 39/130 (30%), Positives = 67/130 (51%), Gaps = 9/130 (6%)
Query: 190 TSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ---RRLK 246
TS ++P ++ ++ ++S EVI+ LL+KF + ++PQ FAL Q ++L
Sbjct: 125 TSFYLP-LDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLS 183
Query: 247 KTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKRE 306
D PL RLL GP + L + + E+ D F L++ L L +EE+ +
Sbjct: 184 IADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDA-----FSIPELQNFLTILEKEEQDK 238
Query: 307 IQRIVTKFNK 316
IQ++ K++K
Sbjct: 239 IQQVQKKYDK 248
>gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isoform A
[Homo sapiens]
Length = 418
Score = 56.2 bits (134), Expect = 4e-08
Identities = 39/130 (30%), Positives = 67/130 (51%), Gaps = 9/130 (6%)
Query: 190 TSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ---RRLK 246
TS ++P ++ ++ ++S EVI+ LL+KF + ++PQ FAL Q ++L
Sbjct: 278 TSFYLP-LDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLS 336
Query: 247 KTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKRE 306
D PL RLL GP + L + + E+ D F L++ L L +EE+ +
Sbjct: 337 IADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDA-----FSIPELQNFLTILEKEEQDK 391
Query: 307 IQRIVTKFNK 316
IQ++ K++K
Sbjct: 392 IQQVQKKYDK 401
>gi|30039698 Ras association (RalGDS/AF-6) domain family member 3
[Homo sapiens]
Length = 238
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 10/115 (8%)
Query: 203 VRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ---RRLKKTDIPLLQRLLQG 259
+ ++S EVI+ LL+KF + SP FAL+ +Q +L + PL RL+ G
Sbjct: 113 LHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAG 172
Query: 260 PSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQRIVTKF 314
P L + ++ ++ F L++ L+ L++EE ++Q + ++
Sbjct: 173 PRTDTLSFVLRE-------HEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRRY 220
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 36.2 bits (82), Expect = 0.043
Identities = 31/112 (27%), Positives = 61/112 (54%), Gaps = 11/112 (9%)
Query: 203 VRVNSNMRTEEVIKQLLQKFKIE----NSPQDFALHIIFATGEQRRLKKTDIPLLQRLLQ 258
+RV+S T++VI+ L +KF+ + +SP+ ++L+ + +GE RRL + PL+ +L
Sbjct: 60 IRVSSTATTQDVIETLAEKFRPDMRMLSSPK-YSLYEVHVSGE-RRLDIDEKPLVVQLNW 117
Query: 259 GPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQR----LNEEEKRE 306
++ R F++ + + I AQ E ++Q L+++EK+E
Sbjct: 118 NKDDREGR-FVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKE 168
>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
sapiens]
Length = 1367
Score = 35.4 bits (80), Expect = 0.073
Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 12/120 (10%)
Query: 111 ELDRTQIPMSEKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMD 170
E+ R +I MS + Q + + K KDEP++ V +T++EAA +R+R++ L
Sbjct: 993 EVAREKITMSRELG-QGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFL--- 1048
Query: 171 RKERQKNRASINGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFK--IENSP 228
N AS+ F H + V + T +K L+ + +EN+P
Sbjct: 1049 ------NEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNP 1102
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 33.9 bits (76), Expect = 0.21
Identities = 31/112 (27%), Positives = 59/112 (52%), Gaps = 12/112 (10%)
Query: 203 VRVNSNMRTEEVIKQLLQKFKIE----NSPQDFALHIIFATGEQRRLKKTDIPLLQRLLQ 258
+RV+S T++VI+ L +KF+ + +SP+ ++L+ + +GE RRL + PL+ +L
Sbjct: 60 IRVSSTATTQDVIETLAEKFRPDMRMLSSPK-YSLYEVHVSGE-RRLDIDEKPLVVQLNW 117
Query: 259 GPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQR----LNEEEKRE 306
++ R L K+ + AQ E ++Q L+++EK+E
Sbjct: 118 NKDDREGRFVL--KNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKE 167
>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 3 [Homo
sapiens]
Length = 1612
Score = 33.9 bits (76), Expect = 0.21
Identities = 31/112 (27%), Positives = 59/112 (52%), Gaps = 12/112 (10%)
Query: 203 VRVNSNMRTEEVIKQLLQKFKIE----NSPQDFALHIIFATGEQRRLKKTDIPLLQRLLQ 258
+RV+S T++VI+ L +KF+ + +SP+ ++L+ + +GE RRL + PL+ +L
Sbjct: 60 IRVSSTATTQDVIETLAEKFRPDMRMLSSPK-YSLYEVHVSGE-RRLDIDEKPLVVQLNW 117
Query: 259 GPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQR----LNEEEKRE 306
++ R L K+ + AQ E ++Q L+++EK+E
Sbjct: 118 NKDDREGRFVL--KNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKE 167
>gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isoform B
[Homo sapiens]
Length = 336
Score = 33.5 bits (75), Expect = 0.28
Identities = 16/44 (36%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Query: 190 TSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFAL 233
TS ++P ++ ++ ++S EVI+ LL+KF + ++PQ FAL
Sbjct: 278 TSFYLP-LDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFAL 320
>gi|157502184 kinesin family member 6 [Homo sapiens]
Length = 814
Score = 33.1 bits (74), Expect = 0.36
Identities = 39/166 (23%), Positives = 73/166 (43%), Gaps = 32/166 (19%)
Query: 187 NHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQRRLK 246
N + SI F + N + EE+ +L+ K +++ Q+ + TGEQR
Sbjct: 328 NLDESISTCRFAQRVALIKNEAVLNEEINPRLVIK-RLQKEIQELKDELAMVTGEQRTEA 386
Query: 247 KTDIPLLQRLLQGPSEKNARIFLMDKDAE---EISSDVAQYINFHFSLLESIL------- 296
T+ LLQ EK FL D+D++ E+ +D+ + ++ F L+ +L
Sbjct: 387 LTEAELLQ------LEKLITSFLEDQDSDSRLEVGADMRK-VHHCFHHLKKLLNDKKILE 439
Query: 297 --------------QRLNEEEKREIQRIVTKFNKEKAIILKCLQNK 328
+ L EEE R+++ I+ + + E I++ L+ +
Sbjct: 440 NNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEINILVNMLKKE 485
>gi|55769587 probable nucleolar complex protein 14 [Homo sapiens]
Length = 857
Score = 32.7 bits (73), Expect = 0.47
Identities = 40/175 (22%), Positives = 69/175 (39%), Gaps = 27/175 (15%)
Query: 154 MSEAALVRKRMKPLMMDRKERQKNRASINGHFYNHETSIFIPAFESETKVRVNSNMRTEE 213
+S A +RKR + L+ + KER K+ F + NSNM EE
Sbjct: 57 VSRARALRKRTQTLLKEYKERDKSN-----------------VFRDKRFGEYNSNMSPEE 99
Query: 214 VIKQLLQKFKIENSPQDFALHIIFATGEQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKD 273
+++++F +E + I+ E L L EK+ I D D
Sbjct: 100 ---KMMKRFALEQQ-RHHEKKSIYNLNEDEELTHYGQSL------ADIEKHNDIVDSDSD 149
Query: 274 AEEISSDVAQYINFHFSLLESILQRLNEEEKREIQRIVTKFNKEKAIILKCLQNK 328
AE+ + A+ HF +L + ++E E ++ ++ + +I K Q K
Sbjct: 150 AEDRGTLSAELTAAHFGGGGGLLHKKTQQEGEEREKPKSRKELIEELIAKSKQEK 204
>gi|239755855 PREDICTED: hypothetical protein [Homo sapiens]
Length = 250
Score = 32.3 bits (72), Expect = 0.62
Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Query: 249 DIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQ 308
D +LQ L + PS+++ ++L KDA E+ + + + + + + + L R ++
Sbjct: 136 DSRVLQELQERPSQRHQMLYLRQKDANELKT-ILRELKYRIGIQSAKLLR----HLKQKD 190
Query: 309 RIVTKFNKEKAIILKCLQ 326
R++ K + I+ CLQ
Sbjct: 191 RLLHKVQRNCDIVTACLQ 208
>gi|239750363 PREDICTED: hypothetical protein XP_002347382 [Homo
sapiens]
Length = 250
Score = 32.3 bits (72), Expect = 0.62
Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Query: 249 DIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQ 308
D +LQ L + PS+++ ++L KDA E+ + + + + + + + L R ++
Sbjct: 136 DSRVLQELQERPSQRHQMLYLRQKDANELKT-ILRELKYRIGIQSAKLLR----HLKQKD 190
Query: 309 RIVTKFNKEKAIILKCLQ 326
R++ K + I+ CLQ
Sbjct: 191 RLLHKVQRNCDIVTACLQ 208
>gi|239744667 PREDICTED: hypothetical protein XP_002343220 [Homo
sapiens]
Length = 250
Score = 32.3 bits (72), Expect = 0.62
Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Query: 249 DIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQ 308
D +LQ L + PS+++ ++L KDA E+ + + + + + + + L R ++
Sbjct: 136 DSRVLQELQERPSQRHQMLYLRQKDANELKT-ILRELKYRIGIQSAKLLR----HLKQKD 190
Query: 309 RIVTKFNKEKAIILKCLQ 326
R++ K + I+ CLQ
Sbjct: 191 RLLHKVQRNCDIVTACLQ 208
>gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7B
[Homo sapiens]
Length = 319
Score = 32.3 bits (72), Expect = 0.62
Identities = 22/98 (22%), Positives = 41/98 (41%), Gaps = 12/98 (12%)
Query: 142 KDEPDSPVLYRTMSEAALVRKRM------------KPLMMDRKERQKNRASINGHFYNHE 189
K+ PD + R + L K++ K M D+K+ ++NR N N +
Sbjct: 91 KEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNED 150
Query: 190 TSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENS 227
+ I +++ + + EEV K L+ + E+S
Sbjct: 151 LHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDS 188
>gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7
[Homo sapiens]
Length = 325
Score = 32.3 bits (72), Expect = 0.62
Identities = 22/98 (22%), Positives = 41/98 (41%), Gaps = 12/98 (12%)
Query: 142 KDEPDSPVLYRTMSEAALVRKRM------------KPLMMDRKERQKNRASINGHFYNHE 189
K+ PD + R + L K++ K M D+K+ ++NR N N +
Sbjct: 91 KEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNED 150
Query: 190 TSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENS 227
+ I +++ + + EEV K L+ + E+S
Sbjct: 151 LHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDS 188
>gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6
[Homo sapiens]
Length = 319
Score = 32.3 bits (72), Expect = 0.62
Identities = 22/98 (22%), Positives = 41/98 (41%), Gaps = 12/98 (12%)
Query: 142 KDEPDSPVLYRTMSEAALVRKRM------------KPLMMDRKERQKNRASINGHFYNHE 189
K+ PD + R + L K++ K M D+K+ ++NR N N +
Sbjct: 91 KEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNED 150
Query: 190 TSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENS 227
+ I +++ + + EEV K L+ + E+S
Sbjct: 151 LHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDS 188
>gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5
[Homo sapiens]
Length = 341
Score = 32.3 bits (72), Expect = 0.62
Identities = 22/98 (22%), Positives = 41/98 (41%), Gaps = 12/98 (12%)
Query: 142 KDEPDSPVLYRTMSEAALVRKRM------------KPLMMDRKERQKNRASINGHFYNHE 189
K+ PD + R + L K++ K M D+K+ ++NR N N +
Sbjct: 91 KEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNED 150
Query: 190 TSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENS 227
+ I +++ + + EEV K L+ + E+S
Sbjct: 151 LHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDS 188
>gi|148612801 KIAA1009 protein [Homo sapiens]
Length = 1403
Score = 32.0 bits (71), Expect = 0.81
Identities = 44/218 (20%), Positives = 85/218 (38%), Gaps = 23/218 (10%)
Query: 78 KPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQI----PMSEKRNSQEDYLSYH 133
K FS+ S D+ SK + + + L T++ + + + E LS
Sbjct: 523 KMFSTLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTR 582
Query: 134 SNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRASINGHFYNHETSIF 193
+ P E DS + ++T S + K L+M ++ ++ +
Sbjct: 583 KKSENP---TETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKAT 639
Query: 194 IPAFESETKVRVNSNMRTEE-----------VIKQLLQKFKIENSPQDFALHIIFA---- 238
E E + ++ + +E +++ L F+ N Q + LH A
Sbjct: 640 FSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRW-LHFGEAADPV 698
Query: 239 TGEQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEE 276
TGE+ + + +I + LLQG ++N R++ KD +E
Sbjct: 699 TGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQE 736
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 31.6 bits (70), Expect = 1.1
Identities = 42/206 (20%), Positives = 87/206 (42%), Gaps = 18/206 (8%)
Query: 138 KPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRASINGHFYNHETSIFIPAF 197
KP ++P +L E A ++ +++ + R++R++ R G E
Sbjct: 343 KPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEE------ 396
Query: 198 ESETKVRVNSNMRTEEVIKQLLQKFKIENSP--QDFALHIIFATGEQRRLKKTDIPL--L 253
E E + ++ ++ +K +IE +D H + A + R LK+ + + L
Sbjct: 397 EEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVED---HSLVAEEKMRLLKEKEKKMEDL 453
Query: 254 QRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEK--REIQRIV 311
+R A+I M+ ++ + N +LE Q + E+++ REIQ+ +
Sbjct: 454 RREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQM 513
Query: 312 TKFNKEKAII---LKCLQNKLVIKTE 334
++E + LQ ++ IKT+
Sbjct: 514 ESRDEETLELKETYSSLQQEVDIKTK 539
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 30.8 bits (68), Expect = 1.8
Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 19/71 (26%)
Query: 245 LKKTDIPLLQRLLQGPSEKNARIFLMDKD-----AEEISSDVAQYINFHFSLLESILQRL 299
LKKT+ L L +E AR L D D A E+ DVAQ RL
Sbjct: 1523 LKKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQQDVAQ--------------RL 1568
Query: 300 NEEEKREIQRI 310
+ KRE+Q++
Sbjct: 1569 QDSTKRELQKL 1579
>gi|169167074 PREDICTED: similar to SET translocation [Homo sapiens]
Length = 309
Score = 30.4 bits (67), Expect = 2.3
Identities = 16/57 (28%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 260 PSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQRIVTKFNK 316
P E +A + L K +E + H +++ + RLNE++ EI ++ K+NK
Sbjct: 50 PEETSASVGLPKKGEKEQQEAIE-----HIDEIQNEIDRLNEQDNEEILKVEQKYNK 101
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,139,799
Number of Sequences: 37866
Number of extensions: 457431
Number of successful extensions: 1705
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 1658
Number of HSP's gapped (non-prelim): 65
length of query: 337
length of database: 18,247,518
effective HSP length: 103
effective length of query: 234
effective length of database: 14,347,320
effective search space: 3357272880
effective search space used: 3357272880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.