Guide to the Human Genome
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Search of human proteins with 28916698

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28916698 transposon-derived Buster3 transposase-like [Homo
sapiens]
         (594 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28916698 transposon-derived Buster3 transposase-like [Homo sa...  1196   0.0  
gi|219521826 zinc finger, BED-type containing 5 [Homo sapiens]        346   3e-95
gi|49574210 zinc finger, BED-type containing 5 [Homo sapiens]         346   3e-95
gi|46195755 SCAN domain containing 3 [Homo sapiens]                   322   5e-88
gi|223633919 hypothetical protein LOC285550 [Homo sapiens]            319   5e-87
gi|115511046 zinc finger protein 258 [Homo sapiens]                   301   9e-82
gi|21495178 hypothetical protein LOC221786 [Homo sapiens]             290   2e-78
gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]           145   8e-35
gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]          145   1e-34
gi|7662294 EPM2A interacting protein 1 [Homo sapiens]                 101   2e-21
gi|55741653 hypothetical protein LOC57691 [Homo sapiens]               43   0.001
gi|149773449 zinc finger protein 862 [Homo sapiens]                    41   0.003
gi|115511057 hypothetical protein LOC256643 [Homo sapiens]             32   1.7  
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]           30   4.8  
gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]             30   4.8  
gi|33188443 microfilament and actin filament cross-linker protei...    30   4.8  
gi|33188445 microfilament and actin filament cross-linker protei...    30   4.8  
gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens]        30   4.8  
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]        30   4.8  
gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Hom...    30   6.3  
gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Hom...    30   6.3  
gi|21071067 TBP-associated factor 5 [Homo sapiens]                     30   6.3  
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...    30   6.3  
gi|157694513 leucine-rich repeat-containing G protein-coupled re...    30   6.3  
gi|88953346 PREDICTED: Tripartite motif-containing protein 43-li...    30   8.2  
gi|40805852 thrombospondin type I domain-containing 1 isoform 2 ...    30   8.2  
gi|8923894 thrombospondin type I domain-containing 1 isoform 1 [...    30   8.2  
gi|113205089 zinc finger, MYM domain containing 1 [Homo sapiens]       30   8.2  
gi|6912500 phosphatidylinositol glycan anchor biosynthesis, clas...    30   8.2  
gi|29029537 phosphatidylinositol glycan anchor biosynthesis, cla...    30   8.2  

>gi|28916698 transposon-derived Buster3 transposase-like [Homo
           sapiens]
          Length = 594

 Score = 1196 bits (3093), Expect = 0.0
 Identities = 594/594 (100%), Positives = 594/594 (100%)

Query: 1   MSKKRKWDDDYVRYWFTCTTEVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAG 60
           MSKKRKWDDDYVRYWFTCTTEVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAG
Sbjct: 1   MSKKRKWDDDYVRYWFTCTTEVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAG 60

Query: 61  HDLNSLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAEKLVKPCA 120
           HDLNSLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAEKLVKPCA
Sbjct: 61  HDLNSLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAEKLVKPCA 120

Query: 121 LEIAQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAETT 180
           LEIAQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAETT
Sbjct: 121 LEIAQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAETT 180

Query: 181 DMDDCSQLMAFVRYIKEREIVEEFLFCEPLQLSMKGIDVFNLFRDFFLKHKIALDVCGSV 240
           DMDDCSQLMAFVRYIKEREIVEEFLFCEPLQLSMKGIDVFNLFRDFFLKHKIALDVCGSV
Sbjct: 181 DMDDCSQLMAFVRYIKEREIVEEFLFCEPLQLSMKGIDVFNLFRDFFLKHKIALDVCGSV 240

Query: 241 CTDGASSMLGENSEFVAYVKKEIPHIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINF 300
           CTDGASSMLGENSEFVAYVKKEIPHIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINF
Sbjct: 241 CTDGASSMLGENSEFVAYVKKEIPHIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINF 300

Query: 301 IKGRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSN 360
           IKGRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSN
Sbjct: 301 IKGRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSN 360

Query: 361 LVDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIE 420
           LVDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIE
Sbjct: 361 LVDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIE 420

Query: 421 KRNFTNFPFLEEIIVSDNEGIFIAAEITLHLQQLSNFFHGYFSIGDLNEASKWILDPFLF 480
           KRNFTNFPFLEEIIVSDNEGIFIAAEITLHLQQLSNFFHGYFSIGDLNEASKWILDPFLF
Sbjct: 421 KRNFTNFPFLEEIIVSDNEGIFIAAEITLHLQQLSNFFHGYFSIGDLNEASKWILDPFLF 480

Query: 481 NIDFVDDSYLMKNDLAELRASGQILMEFETMKLEDFWCAQFTAFPNLAKTALEILMPFAT 540
           NIDFVDDSYLMKNDLAELRASGQILMEFETMKLEDFWCAQFTAFPNLAKTALEILMPFAT
Sbjct: 481 NIDFVDDSYLMKNDLAELRASGQILMEFETMKLEDFWCAQFTAFPNLAKTALEILMPFAT 540

Query: 541 TYLCELGFSSLLHFKTKSRSCFNLSDDIRVAISKKVPRFSDIIEQKLQLQQKSL 594
           TYLCELGFSSLLHFKTKSRSCFNLSDDIRVAISKKVPRFSDIIEQKLQLQQKSL
Sbjct: 541 TYLCELGFSSLLHFKTKSRSCFNLSDDIRVAISKKVPRFSDIIEQKLQLQQKSL 594


>gi|219521826 zinc finger, BED-type containing 5 [Homo sapiens]
          Length = 693

 Score =  346 bits (888), Expect = 3e-95
 Identities = 192/589 (32%), Positives = 311/589 (52%), Gaps = 9/589 (1%)

Query: 3   KKRKWDDDYVRYWFTCTTEVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAGHD 62
           K+RK+D+ Y+ + FT     D     QCVLC  + SN+ L PSKL  H   +H      D
Sbjct: 106 KRRKYDESYLSFGFTYFGNRDAPHA-QCVLCKKILSNSSLAPSKLRRHLETKHAAYKDKD 164

Query: 63  LNSLK-HMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAEKLVKPCAL 121
           ++  K H+ +P +         V +  ++  +ASY  +Y  A     HT+ E L+KPCA 
Sbjct: 165 ISFFKQHLDSPENNKPPTPKI-VNTDNESATEASYNVSYHIALSGEAHTIGELLIKPCAK 223

Query: 122 EIAQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAETTD 181
           ++   +      KK+  V LS+  +  RI +++ DI ++++  +K       +QL E+ D
Sbjct: 224 DVVMRMFDEQYSKKIDAVQLSNSTVARRIKDLAADIEEELVCRLKICD-GFSLQLDESAD 282

Query: 182 MDDCSQLMAFVRYIKEREIVEEFLFCEPLQLSMKGIDVFNLFRDFFLKHKIALDVCGSVC 241
           +   + L+ FVRY   + I E+ L CE LQ +  G ++FN    F  KH+I  + C  VC
Sbjct: 283 VSGLAVLLVFVRYRFNKSIEEDLLLCESLQSNATGEEIFNCINSFMQKHEIEWEKCVDVC 342

Query: 242 TDGASSMLGENSEFVAYVKKEIPHIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINFI 301
           +D + ++ G+ +E V  +K   P    +HCLL  HAL +K +PT L++ L   V++IN+I
Sbjct: 343 SDASRAVDGKIAEAVTLIKYVAPESTSSHCLLYRHALAVKIMPTSLKNVLDQAVQIINYI 402

Query: 302 KGRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSNL 361
           K R    RL +   EE+G +++ LL +TE+RWLSRG++L  +FE+  E+  F+   +  L
Sbjct: 403 KARPHQSRLLKILCEEMGAQHTALLLNTEVRWLSRGKVLVRLFELRRELLVFM-DSAFRL 461

Query: 362 VDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIEK 421
            D   N  + + LAYLAD+F  LNE++ SMQ   +   +  +K+S+ +RK  FW   +E+
Sbjct: 462 SDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEE 521

Query: 422 RNFTNFPFLEEIIVSDNEGI--FIAAEITLHLQQLSNFFHGYFSIGDLNEASKWILDPFL 479
            NF  FP L + +   N  +   I + I  HL+ L      YF +   N+ + W+ +PF 
Sbjct: 522 ENFDCFPTLSDFLTEINSTVDKDICSAIVQHLRGLRATLLKYFPV--TNDNNAWVRNPFT 579

Query: 480 FNIDFVDDSYLMKNDLAELRASGQILMEFETMKLEDFWCAQFTAFPNLAKTALEILMPFA 539
             +            L +L +  Q+   F  + L DFW +    +P++A+ A+ +L+PFA
Sbjct: 580 VTVKPASLVARDYESLIDLTSDSQVKQNFSELSLNDFWSSLIQEYPSIARRAVRVLLPFA 639

Query: 540 TTYLCELGFSSLLHFKTKSRSCFNLSDDIRVAISKKVPRFSDIIEQKLQ 588
           T +LCE GFS     KTK R   + +  +R+ +S   P    I ++K Q
Sbjct: 640 TMHLCETGFSYYAATKTKYRKRLDAAPHMRIRLSNITPNIKRICDKKTQ 688


>gi|49574210 zinc finger, BED-type containing 5 [Homo sapiens]
          Length = 693

 Score =  346 bits (888), Expect = 3e-95
 Identities = 192/589 (32%), Positives = 311/589 (52%), Gaps = 9/589 (1%)

Query: 3   KKRKWDDDYVRYWFTCTTEVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAGHD 62
           K+RK+D+ Y+ + FT     D     QCVLC  + SN+ L PSKL  H   +H      D
Sbjct: 106 KRRKYDESYLSFGFTYFGNRDAPHA-QCVLCKKILSNSSLAPSKLRRHLETKHAAYKDKD 164

Query: 63  LNSLK-HMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAEKLVKPCAL 121
           ++  K H+ +P +         V +  ++  +ASY  +Y  A     HT+ E L+KPCA 
Sbjct: 165 ISFFKQHLDSPENNKPPTPKI-VNTDNESATEASYNVSYHIALSGEAHTIGELLIKPCAK 223

Query: 122 EIAQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAETTD 181
           ++   +      KK+  V LS+  +  RI +++ DI ++++  +K       +QL E+ D
Sbjct: 224 DVVMRMFDEQYSKKIDAVQLSNSTVARRIKDLAADIEEELVCRLKICD-GFSLQLDESAD 282

Query: 182 MDDCSQLMAFVRYIKEREIVEEFLFCEPLQLSMKGIDVFNLFRDFFLKHKIALDVCGSVC 241
           +   + L+ FVRY   + I E+ L CE LQ +  G ++FN    F  KH+I  + C  VC
Sbjct: 283 VSGLAVLLVFVRYRFNKSIEEDLLLCESLQSNATGEEIFNCINSFMQKHEIEWEKCVDVC 342

Query: 242 TDGASSMLGENSEFVAYVKKEIPHIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINFI 301
           +D + ++ G+ +E V  +K   P    +HCLL  HAL +K +PT L++ L   V++IN+I
Sbjct: 343 SDASRAVDGKIAEAVTLIKYVAPESTSSHCLLYRHALAVKIMPTSLKNVLDQAVQIINYI 402

Query: 302 KGRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSNL 361
           K R    RL +   EE+G +++ LL +TE+RWLSRG++L  +FE+  E+  F+   +  L
Sbjct: 403 KARPHQSRLLKILCEEMGAQHTALLLNTEVRWLSRGKVLVRLFELRRELLVFM-DSAFRL 461

Query: 362 VDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIEK 421
            D   N  + + LAYLAD+F  LNE++ SMQ   +   +  +K+S+ +RK  FW   +E+
Sbjct: 462 SDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEE 521

Query: 422 RNFTNFPFLEEIIVSDNEGI--FIAAEITLHLQQLSNFFHGYFSIGDLNEASKWILDPFL 479
            NF  FP L + +   N  +   I + I  HL+ L      YF +   N+ + W+ +PF 
Sbjct: 522 ENFDCFPTLSDFLTEINSTVDKDICSAIVQHLRGLRATLLKYFPV--TNDNNAWVRNPFT 579

Query: 480 FNIDFVDDSYLMKNDLAELRASGQILMEFETMKLEDFWCAQFTAFPNLAKTALEILMPFA 539
             +            L +L +  Q+   F  + L DFW +    +P++A+ A+ +L+PFA
Sbjct: 580 VTVKPASLVARDYESLIDLTSDSQVKQNFSELSLNDFWSSLIQEYPSIARRAVRVLLPFA 639

Query: 540 TTYLCELGFSSLLHFKTKSRSCFNLSDDIRVAISKKVPRFSDIIEQKLQ 588
           T +LCE GFS     KTK R   + +  +R+ +S   P    I ++K Q
Sbjct: 640 TMHLCETGFSYYAATKTKYRKRLDAAPHMRIRLSNITPNIKRICDKKTQ 688


>gi|46195755 SCAN domain containing 3 [Homo sapiens]
          Length = 1325

 Score =  322 bits (826), Expect = 5e-88
 Identities = 195/589 (33%), Positives = 314/589 (53%), Gaps = 11/589 (1%)

Query: 5    RKWDDDYVRYWFTCTTEVDG-TQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAGHDL 63
            RK+D  Y+ + F     +DG   +PQC++C  V +N  ++PSKL  H   +H  ++    
Sbjct: 735  RKYDPSYIEFGFVAV--IDGEVLKPQCIICGDVLANEAMKPSKLKRHLYSKHKEISSQPK 792

Query: 64   NSLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAEKLVKPCALEI 123
               +   +   +S+  + F V+    + L+ASY+ A   AK K P+T+AE LVK C  E+
Sbjct: 793  EFFERKSSEL-KSQPKQVFNVSHINISALRASYKVALPVAKSKTPYTIAETLVKDCIKEV 851

Query: 124  AQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAETTDMD 183
               +LG  A KK+ QVPLS+D I  RI E++ D+  Q++E IK +     +QL E  D+ 
Sbjct: 852  CLEMLGESAAKKVAQVPLSNDTIARRIQELANDMEDQLIEQIKLAKY-FSLQLDECRDIA 910

Query: 184  DCSQLMAFVRYIKEREIVEEFLFCEPLQLSMKGIDVFNLFRDFFL-KHKIALDVCGSVCT 242
            +   L+ +VR+  + +I EEF F   L  +    +++   +++ + K  +    C  VC+
Sbjct: 911  NMIILLVYVRFEHDDDIKEEFFFSASLPTNTTSSELYEAVKNYIVNKCGLEFKFCVGVCS 970

Query: 243  DGASSMLGENSEFVAYVKKEIPHIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINFIK 302
            DGA+SM G++SE V  +K+  P    THC ++  +L +K +  +L   L  +V+++N+IK
Sbjct: 971  DGAASMTGKHSEVVTQIKELAPECKTTHCFIHRESLAMKKISAELNSVLNDIVKIVNYIK 1030

Query: 303  GRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSNLV 362
              + N RLF    + +  ++  LL H E+RWLSRG++L+ +FE+  E+  FL  K     
Sbjct: 1031 SNSLNSRLFSLLCDNMEADHKQLLLHAEIRWLSRGKVLSRMFEIRNELLVFLQGKKPMWS 1090

Query: 363  DGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIEKR 422
              F++  +   LAYL+D+F   N+L+ASMQ       S  +K+    +K   W+ RI   
Sbjct: 1091 QLFKDVNWTARLAYLSDIFSIFNDLNASMQGKNATYFSMADKVEGQKQKLEAWKNRISTD 1150

Query: 423  NFTNFPFLEEIIVSDNEGIFIA---AEITLHLQQLSNFFHGYF-SIGDLNEASKWILDPF 478
             +  F  L  II      + IA     I+ HL  L   F  YF S  D    + WI +PF
Sbjct: 1151 CYDMFHNLTTIINEVGNDLDIAHLRKVISEHLTNLLECFEFYFPSKEDPRIGNLWIQNPF 1210

Query: 479  LFNIDFVDDSYLMKNDLAELRASGQILMEFE-TMKLEDFWCAQFTAFPNLAKTALEILMP 537
            L + D ++ +  +++ L +L     + + FE T  L  FW      +P LA+ AL++L+ 
Sbjct: 1211 LSSKDNLNLTVTLQDKLLKLATDEGLKISFENTASLPSFWIKAKNDYPELAEIALKLLLL 1270

Query: 538  FATTYLCELGFSSLLHFKTKSRSCFNLSDDIRVAISKKVPRFSDIIEQK 586
            F +TYLCE GFS+L   KTK R+  N+   +RVA+S   PR   +  +K
Sbjct: 1271 FPSTYLCETGFSTLSVIKTKHRNSLNIHYPLRVALSSIQPRLDKLTSKK 1319


>gi|223633919 hypothetical protein LOC285550 [Homo sapiens]
          Length = 657

 Score =  319 bits (817), Expect = 5e-87
 Identities = 194/600 (32%), Positives = 326/600 (54%), Gaps = 25/600 (4%)

Query: 5   RKWDDDYVRYWFTCTTEVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAGHDLN 64
           R++++DY++Y F    +     RPQCV+CN++ +N  L+PSKL  H   QH  +    L 
Sbjct: 61  RRYNEDYLKYGFIKCEKPFENDRPQCVICNNILANESLKPSKLKRHLETQHAELIDKPLE 120

Query: 65  SLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAEKLVKPCALEIA 124
             +        S    +   A  E  LL +SY  AY  AKEK  +T AEK++ P  L++ 
Sbjct: 121 YFQRKKKDIKLSTQFLSCSTAVSEKALL-SSYLVAYRVAKEKIANTAAEKIILPACLDMV 179

Query: 125 QIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAETTDMDD 184
           + +    +  KL+ +P +D+ +  RI  +++ +   ++  ++ S +   IQL E+TD+  
Sbjct: 180 RTIFDDKSADKLKTIP-NDNTVSLRICTIAEHLETMLITRLQ-SGIDFAIQLDESTDIGS 237

Query: 185 CSQLMAFVRYIKEREIVEEFLFCEPLQLSMKGIDVFN-LFRDFFLKHKIALDVCGSVCTD 243
           C+ L+ +VRY  + + +E+FL    L   + G+D+F  L R    ++K+    C  + +D
Sbjct: 238 CTTLLVYVRYAWQDDFLEDFLCFLNLTSHLSGLDIFTELERRIVGQYKLNWKNCKGITSD 297

Query: 244 GASSMLGENSEFVAYVKKEIPHIVV-THCLLNPHALVIKTLPTKLRDALFTVVRVINFIK 302
           G ++M G++S  +  + +   +  V  HC ++   L  + +P  L + L   V+V+NFIK
Sbjct: 298 GTATMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLASREIPQNLMEVLKNAVKVVNFIK 357

Query: 303 GRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSNLV 362
           G + N RL + F  EIG  ++ LL+HT++RWLS+G+IL+ ++E+  EI+ FL  K S+L 
Sbjct: 358 GSSLNSRLLETFCSEIGTNHTHLLYHTKIRWLSQGKILSRVYELRNEIHFFLIEKKSHLA 417

Query: 363 DGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIEKR 422
             FE+  +   LAYL D+F  LNELS  +Q    +     E++  F +    WQ R++  
Sbjct: 418 SIFEDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSN 477

Query: 423 NFTNFPF------LEEIIVSDNEGIFIAAEITLHLQQLSNFFHGYF---SIGDLNEASKW 473
             + + F      +EE I+++N    I  EI LHL  LS  F+ +F       L E S W
Sbjct: 478 RPSYYMFPRFLQHIEENIINENILKEIKLEILLHLTSLSQTFNHFFPEEKFETLRENS-W 536

Query: 474 ILDPFLF-------NIDFVDDSYLMKNDLAELRASGQILMEFETMKLEDFWCAQFTAFPN 526
           + DPF F        ++ V +    +N+L +L +S  +  ++ET+ L  FW      FP 
Sbjct: 537 VKDPFAFRHPESIIELNLVPEE---ENELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPL 593

Query: 527 LAKTALEILMPFATTYLCELGFSSLLHFKTKSRSCFNLSDDIRVAISKKVPRFSDIIEQK 586
           L++ ++ +L+PF TT LCELGFS L   KTK R+  N +  +RVA+S  VP +++++ ++
Sbjct: 594 LSRKSVLLLLPFTTTSLCELGFSILTQLKTKERNGLNCAAVMRVALSSCVPDWNELMNRQ 653


>gi|115511046 zinc finger protein 258 [Homo sapiens]
          Length = 1325

 Score =  301 bits (772), Expect = 9e-82
 Identities = 183/600 (30%), Positives = 322/600 (53%), Gaps = 23/600 (3%)

Query: 2    SKKRK------WDDDYVRYWFT-CTTEVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQ 54
            SKK++      +D +Y++  F  C    + + RPQCV+C  + S+ +++P+ LS H   +
Sbjct: 733  SKKKRLGFFQTYDTEYLKVGFIICPGSKESSPRPQCVICGEILSSENMKPANLSHHLKTK 792

Query: 55   HGGVAGHDLNSLKHMPAPSD-QSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAE 113
            H  +    ++  +      + Q+ +LK   +   E +L++ASY  A+  A  K P ++AE
Sbjct: 793  HSELENKPVDFFEQKSLEMECQNSSLKKCLLV--EKSLVKASYLIAFQTAASKKPFSIAE 850

Query: 114  KLVKPCALEIAQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVG 173
            +L+KP  +E+   VLG  A  K++ +PLS+  I  RIDE+S DI  Q+++ ++ S     
Sbjct: 851  ELIKPYLVEMCSEVLGSSAGDKMKTIPLSNVTIQHRIDELSADIEDQLIQKVRESKW-FA 909

Query: 174  IQLAETTDMDDCSQLMAFVRYIKE--REIVEEFLFCEPLQLSMKGIDVFNLFRDFFLKHK 231
            +Q+ E++++ + + L+ ++R+I    R++ EE LFC  +   + G ++F L   +     
Sbjct: 910  LQIDESSEISNITLLLCYIRFIDYDCRDVKEELLFCIEMPTQITGFEIFELINKYIDSKS 969

Query: 232  IALDVCGSVCTDGASSMLGENSEFVAYVKKEIPHIVV-THCLLNPHALVIKTLPTKLRDA 290
            +    C  +CTDGA+SM G  S   A +++   +    THC ++   LV + L   L   
Sbjct: 970  LNWKHCVGLCTDGAASMTGRYSGLKAKIQEVAMNTAAFTHCFIHRERLVAEKLSPCLHKI 1029

Query: 291  LFTVVRVINFIKGRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEI 350
            L    ++++FIK  A N R+     EE+G E+  L  H E+RW+SRG++L  +FE+  EI
Sbjct: 1030 LLQSAQILSFIKSNALNSRMLTILCEEMGSEHVSLPLHAEVRWISRGRMLKRLFELRHEI 1089

Query: 351  NQFLHHKSSNLVDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVR 410
              FL  K S+L   F ++E+   LAYL+D+F  +NEL+ S+Q T     +   K+  F R
Sbjct: 1090 EIFLSQKHSDLAKYFHDEEWVGKLAYLSDIFSLINELNLSLQGTLTTFFNLCNKIDVFKR 1149

Query: 411  KFPFWQKRIEKRNFTNFPFLEEIIVSDNEGI---FIAAEITLHLQQLSNFFHGYF-SIGD 466
            K   W KR ++ ++  FP   E   S++ G+    I   I  HL+ LS  F   F    D
Sbjct: 1150 KLKMWLKRTQENDYDMFPSFSEF--SNSSGLNMTDITRIIFEHLEGLSQVFSDCFPPEQD 1207

Query: 467  LNEASKWILDPFLFNIDFVDDSYLMKNDLAELRASGQILMEFETMKLEDFWCAQFTAFPN 526
            L   + WI+ PF+ N    + +   +  L EL +   +   F+++ +  FW    T++P 
Sbjct: 1208 LRSGNLWIIHPFM-NHQNNNLTDFEEEKLTELSSDLGLQALFKSVSVTQFWINAKTSYPE 1266

Query: 527  LAKTALEILMPFATTYLCELGFSSLLHFKTKSRSCFNLSDDIRVAISKKVPRFSDIIEQK 586
            L + A++ L+PF+T YLC+  FS+L   ++K ++       +R+A++  +PR   ++++K
Sbjct: 1267 LHERAMKFLLPFSTVYLCDAAFSALT--ESKQKNLLGSGPALRLAVTSLIPRIEKLVKEK 1324


>gi|21495178 hypothetical protein LOC221786 [Homo sapiens]
          Length = 573

 Score =  290 bits (743), Expect = 2e-78
 Identities = 180/552 (32%), Positives = 298/552 (53%), Gaps = 31/552 (5%)

Query: 49  DHFNRQHGGVAGHDLNSLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNP 108
           DHF ++         N ++  P    +S T+         +  L +SY  AY  AKEK  
Sbjct: 34  DHFQKER--------NKVESSPQVLSRSTTMN--------ERALLSSYLVAYRVAKEKMA 77

Query: 109 HTVAEKLVKPCALEIAQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKAS 168
           HT AEK++ P  +++ + +    +  KL+ +PLSD+ I  RI  +++ +   ++  ++ S
Sbjct: 78  HTAAEKIILPACMDMVRTIFDDKSADKLRTIPLSDNTISRRICTIAKHLEAMLITRLQ-S 136

Query: 169 PLKVGIQLAETTDMDDCSQLMAFVRYIKEREIVEEFLFCEPLQLSMKGIDVFNLFRDFFL 228
            +   IQL E+TD+  C  L+ +VRY+ + + VE+ L C  L   + G+D+F    +  L
Sbjct: 137 GIDFAIQLDESTDIASCPTLLVYVRYVWQDDFVEDLLCCLNLNSHITGLDLFTELENCLL 196

Query: 229 -KHKIALDVCGSVCTDGASSMLGENSEFVAYVKKEIPHIVV-THCLLNPHALVIKTLPTK 286
            ++K+    C  + +DG ++M G++S     + +   +  V  HC ++  ALV K +   
Sbjct: 197 GQYKLNWKHCKGISSDGTANMTGKHSRLTEKLLEATHNNAVWNHCFIHREALVSKEISPS 256

Query: 287 LRDALFTVVRVINFIKGRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEM 346
           L D L   V+ +NFIKG + N RL + F  EIG+ ++ LLFHTE+RWLS+G++L+ ++E+
Sbjct: 257 LMDVLKNAVKTVNFIKGSSLNSRLLEIFCSEIGVNHTHLLFHTEVRWLSQGKVLSRVYEL 316

Query: 347 YEEINQFLHHKSSNLVDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLS 406
             EI  FL  K S+L + FE+  +   LAYL+D+F  LNELS  MQ    +     E + 
Sbjct: 317 RNEIYIFLVEKQSHLANIFEDDIWVTKLAYLSDIFGILNELSLKMQGKNNDIFQYLEHIL 376

Query: 407 AFVRKFPFWQKRIEKRNFTNFPF------LEEIIVSDNEGIFIAAEITLHLQQLSNFFHG 460
            F +    WQ R++    + + F      +EE I++++    I  EI LHL  LS  F+ 
Sbjct: 377 GFQKTLLLWQARLKSNRPSYYMFPTLLQHIEENIINEDCLKEIKLEILLHLTSLSQTFNY 436

Query: 461 YFSIGDLNEASK--WILDPFLF-NIDFVDDSYL---MKNDLAELRASGQILMEFETMKLE 514
           YF         +  W+ DPF F N + + +  L    +N+L +L +S  +   ++ + L 
Sbjct: 437 YFPEEKFESLKENIWMKDPFAFQNPESIIELNLEPEEENELLQLSSSFTLKNYYKILSLS 496

Query: 515 DFWCAQFTAFPNLAKTALEILMPFATTYLCELGFSSLLHFKTKSRSCFNLSDDIRVAISK 574
            FW      FP L++ ++ +L+PF TTYLCELGFS L   KTK R+  N + D+RVA+S 
Sbjct: 497 AFWIKIKDDFPLLSRKSILLLLPFTTTYLCELGFSILTRLKTKKRNRLNSAPDMRVALSS 556

Query: 575 KVPRFSDIIEQK 586
            VP + +++ ++
Sbjct: 557 CVPDWKELMNRQ 568


>gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]
          Length = 949

 Score =  145 bits (367), Expect = 8e-35
 Identities = 108/425 (25%), Positives = 206/425 (48%), Gaps = 20/425 (4%)

Query: 150 IDEMSQDILQQVLEDIKASPLKVGIQLAETTDMDDCSQLMAFVRYIKER-EIVEEFLFCE 208
           +++++ ++ +++ E I+ S +   I + E TD+++ +QL  F+R + E  ++ EE L   
Sbjct: 526 VEDLAGNLWEKLREKIR-SFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTV 584

Query: 209 PLQLSMKGIDVFNLFRDFFLKHKIALDVCGSVCTDGASSMLGENSEFVAYVKKEIP---- 264
           P+  +  G ++F+       K  I      SV + G  +M+  N+  V  +K  +     
Sbjct: 585 PMTGTKSGNEIFSRVEKSLKKFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCK 644

Query: 265 --HIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINFIKGRAPNHRLFQAFFEEIGIEY 322
              +    C+++P +L  + L  K+   +  VV+ +N+I  R  NH  F     E+  +Y
Sbjct: 645 GAELKSICCIIHPESLCAQKL--KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQY 702

Query: 323 SVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSNLVDGFENKEFKIHLAYLADLFK 382
             LL++TE++WLSRG +L   FE  EEI+ F+  +   L     + ++   LA+L D+  
Sbjct: 703 GSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQ-LSSIDWIRDLAFLVDMTM 761

Query: 383 HLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIEKRNFTNFPFLEEIIVSDNEGIF 442
           HLN L+ S+Q          + + AF+ K   W+  + + N  +FP L+    ++++G+ 
Sbjct: 762 HLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGLN 821

Query: 443 IAAEITLHLQQLSNFFHGYFSIGDLNEASKWIL-DPFLFNIDFVDDSYLMKNDLAELRAS 501
              +I     +L   F    S   L E+   +   PF   ID V +   M  ++ +L+ +
Sbjct: 822 YIPKIA----ELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQM--EVIDLQCN 875

Query: 502 GQILMEFETMKLEDFWCAQFTAFPNLAKTALEILMPFATTYLCELGFSSLLHFKTKSRSC 561
             +  +++ + + +F+   + ++P       +IL  F +TY+CE  FS +   KTK   C
Sbjct: 876 TVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTK--YC 933

Query: 562 FNLSD 566
             L D
Sbjct: 934 SQLKD 938


>gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]
          Length = 949

 Score =  145 bits (366), Expect = 1e-34
 Identities = 108/425 (25%), Positives = 206/425 (48%), Gaps = 20/425 (4%)

Query: 150 IDEMSQDILQQVLEDIKASPLKVGIQLAETTDMDDCSQLMAFVRYIKER-EIVEEFLFCE 208
           +++++ ++ +++ E I+ S +   I + E TD+++ +QL  F+R + E  ++ EE L   
Sbjct: 526 VEDLAGNLWEKLREKIR-SFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTV 584

Query: 209 PLQLSMKGIDVFNLFRDFFLKHKIALDVCGSVCTDGASSMLGENSEFVAYVKKEIP---- 264
           P+  +  G ++F        K  I      SV + G  +M+  N+  V  +K  +     
Sbjct: 585 PMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCK 644

Query: 265 --HIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINFIKGRAPNHRLFQAFFEEIGIEY 322
              +    C+++P +L  + L  K+   +  VV+ +N+I  R  NH  F     E+  +Y
Sbjct: 645 GAELKSICCIIHPESLCAQKL--KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQY 702

Query: 323 SVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSNLVDGFENKEFKIHLAYLADLFK 382
             LL++TE++WLSRG +L   FE  EEI+ F+  +   L     + ++   LA+L D+  
Sbjct: 703 GSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQ-LSSIDWIRDLAFLVDMTM 761

Query: 383 HLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIEKRNFTNFPFLEEIIVSDNEGIF 442
           HLN L+ S+Q          + + AF+ K   W+  + + N  +FP L+ +  ++++G+ 
Sbjct: 762 HLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLN 821

Query: 443 IAAEITLHLQQLSNFFHGYFSIGDLNEASKWIL-DPFLFNIDFVDDSYLMKNDLAELRAS 501
              +I     +L   F    S   L E+   +   PF   ID V +   M  ++ +L+ +
Sbjct: 822 YIPKIA----ELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQM--EVIDLQCN 875

Query: 502 GQILMEFETMKLEDFWCAQFTAFPNLAKTALEILMPFATTYLCELGFSSLLHFKTKSRSC 561
             +  +++ + + +F+   + ++P       +IL  F +TY+CE  FS +   KTK   C
Sbjct: 876 TVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTK--YC 933

Query: 562 FNLSD 566
             L D
Sbjct: 934 SQLKD 938


>gi|7662294 EPM2A interacting protein 1 [Homo sapiens]
          Length = 607

 Score =  101 bits (252), Expect = 2e-21
 Identities = 108/476 (22%), Positives = 210/476 (44%), Gaps = 26/476 (5%)

Query: 130 PDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLE---DIKASPLKVGIQLAETTDMDDCS 186
           P+    LQ V LS D+   RI  + +++  Q+     D KA  L +  Q     +    +
Sbjct: 134 PEHVSVLQGVDLSPDITRQRILSIDRNLRNQLFNRARDFKAYSLALDDQAFVAYE----N 189

Query: 187 QLMAFVRYI-KEREIVEEFLFCEPLQLSMKGIDVFNLFRDFFLKHKIALDVCGSVCTDGA 245
            L+ F+R +  E E+ E+ L    L        + +   +      ++L     + T   
Sbjct: 190 YLLVFIRGVGPELEVQEDLLTIINLTHHFSVGALMSAILESLQTAGLSLQRMVGLTTTHT 249

Query: 246 SSMLGENSEFVAYVKKEI--PHIV-VTHCLLNPHALVIKTLPTKLRDALFTVVRVINFIK 302
             M+GENS  V+Y++++   P+   V H     H  ++ +    +   + T+   I  IK
Sbjct: 250 LRMIGENSGLVSYMREKAVSPNCWNVIHYSGFLHLELLSSYDVDVNQIINTISEWIVLIK 309

Query: 303 GRAPNHRLFQAFFEEIGIEYSVLLFHTEMR-WLSRGQILTHIFEMYEEINQFLHHKSSNL 361
            R      FQ    E   E+   +    +  WL RG+ L  IF + +E+  FL    +  
Sbjct: 310 TRGVRRPEFQTLLTESESEHGERVNGRCLNNWLRRGKTLKLIFSLRKEMEAFLVSVGATT 369

Query: 362 VDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIEK 421
           V  F +K++     +L D+ +HL ELS  ++ + +   +A + +  F  K   +Q+ IE+
Sbjct: 370 VH-FSDKQWLCDFGFLVDIMEHLRELSEELRVSKVFAAAAFDHICTFEVKLNLFQRHIEE 428

Query: 422 RNFTNFPFLEEII------VSDNEGIFIAAEITLHLQQLSNFFHGYF-SIGDLNEASKWI 474
           +N T+FP L E++        ++E IF      + + +L   F  +F  +  + +  +  
Sbjct: 429 KNLTDFPALREVVDELKQQNKEDEKIFDPDRYQMVICRLQKEFERHFKDLRFIKKDLELF 488

Query: 475 LDPFLFNIDFVDDSYLMKNDLAELRASGQILMEFETMKLEDFWCA-QFTAFPNLAKTALE 533
            +PF F  ++   S  ++ +L +L+A+  +  E+    L  F+      ++P +   A +
Sbjct: 489 SNPFNFKPEYAPIS--VRVELTKLQANTNLWNEYRIKDLGQFYAGLSAESYPIIKGVACK 546

Query: 534 ILMPFATTYLCELGFSSLL---HFKTKSRSCFNLSDDIRVAISKKVPRFSDIIEQK 586
           +   F +  +CE  FS L    H  ++  +  +L    RVA ++  P + D++ ++
Sbjct: 547 VASLFDSNQICEKAFSYLTRNQHTLSQPLTDEHLQALFRVATTEMEPGWDDLVRER 602


>gi|55741653 hypothetical protein LOC57691 [Homo sapiens]
          Length = 787

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 41/183 (22%), Positives = 73/183 (39%), Gaps = 21/183 (11%)

Query: 241 CTDGASSMLGENSEFVAYVKKEIPHIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINF 300
           C+DGA+++LG  S     + +  P I++ +CL   H L +        D   + ++ IN 
Sbjct: 388 CSDGANTILGRKSGVATKLLENFPEIIIWNCL--NHRLQLSL------DDSISEIKQINH 439

Query: 301 IK---------GRAPNH---RLFQAFFEEIGIEYSVLLFHTEMRWLSRG-QILTHIFEMY 347
           +K            PN    +L     +E+  E   +      RW +   Q  T ++  Y
Sbjct: 440 LKIFIDKIYSIYHQPNKNQTKLLGTVAKELETEIIKIGRVMGPRWAACSLQAATAVWHAY 499

Query: 348 EEINQFLHHKSSNLVDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSA 407
             +     H  S L     N  F   LA + D+ +  + LS ++Q    N   A++ +  
Sbjct: 500 PILYMHFSHSYSGLAKRLANINFLQDLALMIDILEEFSVLSTALQSRSTNIKKAQKLIKR 559

Query: 408 FVR 410
            +R
Sbjct: 560 TIR 562


>gi|149773449 zinc finger protein 862 [Homo sapiens]
          Length = 1169

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 6/126 (4%)

Query: 150 IDEMSQDILQQVLEDIKASPLKVGIQLAETTDMDDCSQLMAFVRYIKEREIVEEFLFCEP 209
           I  +S+ + +++LED++ SP  V + L  +TD  + + +  ++RY K+ E+ E ++   P
Sbjct: 603 IKYISETLKREILEDVRNSPC-VSVLLDSSTDASEQACVGIYIRYFKQMEVKESYITLAP 661

Query: 210 LQLSMKGIDVFNLFRDFFLKHKIALDVCGSVC---TDGASSMLGENSEFVAYVKKEIPHI 266
           L  S      F        +  I     G V    TDG S+ML      V   ++ IP +
Sbjct: 662 L-YSETADGYFETIVSALDELDIPFRKPGWVVGLGTDG-SAMLSCRGGLVEKFQEVIPQL 719

Query: 267 VVTHCL 272
           +  HC+
Sbjct: 720 LPVHCV 725


>gi|115511057 hypothetical protein LOC256643 [Homo sapiens]
          Length = 682

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 12/123 (9%)

Query: 67  KHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAEKL-------VKPC 119
           K +    D  +T+  F VAS   T  Q S+    +  K +N H V E L        KP 
Sbjct: 409 KSLTVKVDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPT 468

Query: 120 ALEIAQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAET 179
             E AQ ++    Q K    P     +H R   M QDI +    D+   PL    ++   
Sbjct: 469 G-EFAQEIITIIHQVKANYFPSPGITLHERFSTM-QDIHK---ADVNEIPLNSDPEIHRR 523

Query: 180 TDM 182
            DM
Sbjct: 524 IDM 526


>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
          Length = 2986

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 5/162 (3%)

Query: 51  FNRQHGGVAGHDLNSLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHT 110
           F  +H GV G  L+  + +    D  E + A    ++ D LL+A+ Q A     E +P  
Sbjct: 559 FLSKHTGV-GKSLHRARALQKRHDDFEEV-AQNTYTNADKLLEAAEQLAQ--TGECDPEE 614

Query: 111 VAEKLVKPCALEIAQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPL 170
           +  K  +   + I   V   + +K L  + +S       +    +D+ +++LED+ A  +
Sbjct: 615 IY-KAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSV 673

Query: 171 KVGIQLAETTDMDDCSQLMAFVRYIKEREIVEEFLFCEPLQL 212
               +L +       + L A +  IKE E + + L   P  L
Sbjct: 674 DAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSL 715


>gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]
          Length = 1663

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 5/162 (3%)

Query: 51  FNRQHGGVAGHDLNSLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHT 110
           F  +H GV G  L+  + +    D  E + A    ++ D LL+A+ Q A     E +P  
Sbjct: 559 FLSKHTGV-GKSLHRARALQKRHDDFEEV-AQNTYTNADKLLEAAEQLAQ--TGECDPEE 614

Query: 111 VAEKLVKPCALEIAQIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPL 170
           +  K  +   + I   V   + +K L  + +S       +    +D+ +++LED+ A  +
Sbjct: 615 IY-KAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSV 673

Query: 171 KVGIQLAETTDMDDCSQLMAFVRYIKEREIVEEFLFCEPLQL 212
               +L +       + L A +  IKE E + + L   P  L
Sbjct: 674 DAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSL 715


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 15/97 (15%)

Query: 338  QILTHIFEMYEEINQFLHHKSSNLVDGFENKEFKI-----------HLAYLADLFKHLNE 386
            Q +TH F+  +E+N  +  +  NL D  E+   ++           H   + +L K   E
Sbjct: 2687 QDITHFFQQIQELNLEMEDQQENL-DTLEHLVTELSSCGFALDLCQHQDRVQNLRKDFTE 2745

Query: 387  LSASMQRTGMNTVSAREKLSAF---VRKFPFWQKRIE 420
            L  +++    +  S +E+L  F   VR F  W K  E
Sbjct: 2746 LQKTVKEREKDASSCQEQLDEFRKLVRTFQKWLKETE 2782


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 15/97 (15%)

Query: 338  QILTHIFEMYEEINQFLHHKSSNLVDGFENKEFKI-----------HLAYLADLFKHLNE 386
            Q +TH F+  +E+N  +  +  NL D  E+   ++           H   + +L K   E
Sbjct: 2185 QDITHFFQQIQELNLEMEDQQENL-DTLEHLVTELSSCGFALDLCQHQDRVQNLRKDFTE 2243

Query: 387  LSASMQRTGMNTVSAREKLSAF---VRKFPFWQKRIE 420
            L  +++    +  S +E+L  F   VR F  W K  E
Sbjct: 2244 LQKTVKEREKDASSCQEQLDEFRKLVRTFQKWLKETE 2280


>gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens]
          Length = 625

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 22/93 (23%), Positives = 45/93 (48%), Gaps = 7/93 (7%)

Query: 361 LVDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIE 420
           +      +EF+   A L +L  +  +LS  +++ G+   S R+K++   ++F   QK + 
Sbjct: 1   MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALS 60

Query: 421 KRNFTNFPFLEEIIVSDNEGIFIAAEITLHLQQ 453
           K          E+++S+NE +    +  LH Q+
Sbjct: 61  KSKKAQ---EVEVLLSENEML----QAKLHSQE 86


>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
          Length = 841

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 22/93 (23%), Positives = 45/93 (48%), Gaps = 7/93 (7%)

Query: 361 LVDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIE 420
           +      +EF+   A L +L  +  +LS  +++ G+   S R+K++   ++F   QK + 
Sbjct: 1   MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALS 60

Query: 421 KRNFTNFPFLEEIIVSDNEGIFIAAEITLHLQQ 453
           K          E+++S+NE +    +  LH Q+
Sbjct: 61  KSKKAQ---EVEVLLSENEML----QAKLHSQE 86


>gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Homo
           sapiens]
          Length = 1194

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 2/83 (2%)

Query: 156 DILQQVLEDIKASPLKVGIQLAETTDMDDCSQLMAFVRYIKEREIVEEFLFCEPLQLSMK 215
           ++ QQ +E +K    ++ +QL ETT   + ++L   ++    R+ V++    +PL  S K
Sbjct: 298 ELQQQTIESLKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKKVDKATMAQPLVFS-K 356

Query: 216 GIDVFNLFRDFFL-KHKIALDVC 237
            ++     RD  +  H   +D C
Sbjct: 357 VVEAVVQTRDQMVGSHMDLVDTC 379


>gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Homo
           sapiens]
          Length = 1352

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 2/83 (2%)

Query: 156 DILQQVLEDIKASPLKVGIQLAETTDMDDCSQLMAFVRYIKEREIVEEFLFCEPLQLSMK 215
           ++ QQ +E +K    ++ +QL ETT   + ++L   ++    R+ V++    +PL  S K
Sbjct: 456 ELQQQTIESLKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKKVDKATMAQPLVFS-K 514

Query: 216 GIDVFNLFRDFFL-KHKIALDVC 237
            ++     RD  +  H   +D C
Sbjct: 515 VVEAVVQTRDQMVGSHMDLVDTC 537


>gi|21071067 TBP-associated factor 5 [Homo sapiens]
          Length = 800

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 15/39 (38%), Positives = 27/39 (69%), Gaps = 2/39 (5%)

Query: 134 KKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKV 172
           KKL+ V  + D+  S ID+ S D+L++++++  AS LK+
Sbjct: 502 KKLRSVKQASDL--SLIDKESDDVLERIMDEKTASELKI 538


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 9/72 (12%)

Query: 48  SDHFNRQHGGVAGHDLNSLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKN 107
           S  +NR+HGG  G D + +      S+ +E +  F   + +++LL+  Y + +     + 
Sbjct: 5   SADYNREHGGPEGMDPDGV----IESNWNEIVDNFDDMNLKESLLRGIYAYGF-----EK 55

Query: 108 PHTVAEKLVKPC 119
           P  + ++ + PC
Sbjct: 56  PSAIQQRAIIPC 67


>gi|157694513 leucine-rich repeat-containing G protein-coupled
           receptor 4 [Homo sapiens]
          Length = 951

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 394 TGMNTVSAREKLSAFVRKFPFWQKRIEKRN---FTNFPFLEEIIVSDNEGIFIAAEITLH 450
           +G    +  E LSAF +        I +     F NFPFLEE+ ++ N+  FI  +    
Sbjct: 44  SGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSG 103

Query: 451 LQQL 454
           L++L
Sbjct: 104 LKEL 107


>gi|88953346 PREDICTED: Tripartite motif-containing protein 43-like
           protein 1 [Homo sapiens]
          Length = 446

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 13/55 (23%), Positives = 24/55 (43%)

Query: 308 HRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSNLV 362
           H+  +   E +  EY  +    +  W+   Q   H+ EMY+E+ +  H     L+
Sbjct: 191 HKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPEVELL 245


>gi|40805852 thrombospondin type I domain-containing 1 isoform 2
           [Homo sapiens]
          Length = 799

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 23/86 (26%), Positives = 34/86 (39%)

Query: 21  EVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAGHDLNSLKHMPAPSDQSETLK 80
           E  GT+ P   L  S      LR   L DH      G+   + +  +  P+PS +S + K
Sbjct: 661 EASGTRGPLNPLPKSYTLGQPLRKPDLGDHQAGLVAGIERTEPHRARRGPSPSHKSVSRK 720

Query: 81  AFGVASHEDTLLQASYQFAYLCAKEK 106
                S +D   + S      C K+K
Sbjct: 721 QSSPISPKDNYQRVSSLSPSQCRKDK 746


>gi|8923894 thrombospondin type I domain-containing 1 isoform 1
           [Homo sapiens]
          Length = 852

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 23/86 (26%), Positives = 34/86 (39%)

Query: 21  EVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAGHDLNSLKHMPAPSDQSETLK 80
           E  GT+ P   L  S      LR   L DH      G+   + +  +  P+PS +S + K
Sbjct: 714 EASGTRGPLNPLPKSYTLGQPLRKPDLGDHQAGLVAGIERTEPHRARRGPSPSHKSVSRK 773

Query: 81  AFGVASHEDTLLQASYQFAYLCAKEK 106
                S +D   + S      C K+K
Sbjct: 774 QSSPISPKDNYQRVSSLSPSQCRKDK 799


>gi|113205089 zinc finger, MYM domain containing 1 [Homo sapiens]
          Length = 1142

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 17/170 (10%)

Query: 141 LSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAETTDMDDCSQLMAFVRYIKERE- 199
           +  D+I     EM QDI+ ++ +    S     I   ET +     QL   VRY ++   
Sbjct: 617 IQSDIIEIIKTEMLQDIVNEINDSSAFS-----IICDETINSAMKEQLSICVRYPQKSSK 671

Query: 200 ---IVEEFLFCEPLQLSMKGIDVFNLFRDFFLKHKIALDVCGSVCTDGASSMLGENSEFV 256
              I E FL     +  M G  +    + +  +  + +D       D  +++  + ++  
Sbjct: 672 AILIKERFLGFVDTE-EMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIA 730

Query: 257 AYVKKEIPHIVVTHCLLNPHALVIKTL-----PTKLRDALFTVVRVINFI 301
           A  KKE P  +  HC    H L +  +       +LR AL T+  + N I
Sbjct: 731 AEFKKEEPRALYIHCY--AHFLDLSIIRFCKEVKELRSALKTLSSLFNTI 778


>gi|6912500 phosphatidylinositol glycan anchor biosynthesis, class N
           [Homo sapiens]
          Length = 931

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 194 YIKEREIVEEFLFCEPL-QLSMKGIDVFNLFRDFFLKHKIALDVCGSVCTDGASSMLGEN 252
           YIK R+  E    C+ L  L++KG+  ++ +  FFL   + +   G + +  +  ++  +
Sbjct: 408 YIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWI-SYASLLIIKSH 466

Query: 253 SEFVAYVKKEI 263
           S  +  V KE+
Sbjct: 467 SNLIKGVSKEV 477


>gi|29029537 phosphatidylinositol glycan anchor biosynthesis, class
           N [Homo sapiens]
          Length = 931

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 194 YIKEREIVEEFLFCEPL-QLSMKGIDVFNLFRDFFLKHKIALDVCGSVCTDGASSMLGEN 252
           YIK R+  E    C+ L  L++KG+  ++ +  FFL   + +   G + +  +  ++  +
Sbjct: 408 YIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWI-SYASLLIIKSH 466

Query: 253 SEFVAYVKKEI 263
           S  +  V KE+
Sbjct: 467 SNLIKGVSKEV 477


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,433,364
Number of Sequences: 37866
Number of extensions: 847070
Number of successful extensions: 2593
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2532
Number of HSP's gapped (non-prelim): 36
length of query: 594
length of database: 18,247,518
effective HSP length: 108
effective length of query: 486
effective length of database: 14,157,990
effective search space: 6880783140
effective search space used: 6880783140
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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